MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Ziltivekimab | Ziltivekimab (COR-001) is a humanized monoclonal antibody against IL-6 that effectively reduces serum CRP levels. Ziltivekimab possesses anti-inflammatory activity and can be used in research related to chronic systemic inflammation associated with chronic kidney disease (CKD) and cardiovascular diseases such as atherosclerosis [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: COR-001. CAS No. 2226654-05-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99505. |  |
| Zilucoplan | Zilucoplan (RA101495), a 15-amino acid macrocyclic peptide, is a potent complement component 5 (C5) inhibitor. Zilucoplan can be used in research of immune-mediated necrotising myopathy (IMNM) [1] [2]. Uses: Scientific research. Group: Peptides. Alternative Names: RA101495; RA3193. CAS No. 1841136-73-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P3502. | |
| Zilurgisertib | Zilurgisertib (INCB-000928; NBU-928) is a selective ALK 2 inhibitor for researching diseases such as cancer. Uses: Scientific research. Group: Signaling pathways. Alternative Names: INCB-000928; NBU-928. CAS No. 2173389-57-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145608. | |
| ZIM | ZIM, a norbornene derived from 4-Aminoantipyrine, is a potent inducer of DNA damage, causing genomic and chromosomal damage as well as inducing cell death and activating phagocytosis. ZIM has chemotherapeutic potential for use in cancer research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 301298-87-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-152246. | |
| Zimberelimab | Zimberelimab (GLS-010) is a fully human IgG4 anti- PD-1 monoclonal antibody with an EC 50 of 210 pM for human PD-1. Zimberelimab effectively blocks the binding of PD-L1 and PD-L2 to cell-surface PD-1 in CHO-S cells, with IC 50 values of 580 pM and 670 pM, respectively. Zimberelimab shows antitumor activities, and can be used for various cancers research, including cervical cancer, non-small cell lung cancer and classical Hodgkins lymphoma [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: GLS-010; AB-122; WBP-3055. CAS No. 2259860-24-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99109. | |
| Zimelidine dihydrochloride | Zimelidine dihydrochloride is a potent and selective inhibitor of serotonin 5-HT uptake and SERT. Zimelidine dihydrochloride is an antidepressant [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 60525-15-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110023. | |
| Zinc dethyldithiocarbamate | Zinc Diethyldithiocarbamate is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Ethyl ziram. CAS No. 14324-55-1. Pack Sizes: 25 g. Product ID: HY-101505. | |
| Zinc Gluconate | Zinc Gluconate has the potential for the research of common cold, cancer, and a nutrition supplement as a food additive [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 4468-2-4. Pack Sizes: 10 mM * 1 mL; 25 g. Product ID: HY-W145499. | |
| Zincon sodium | Zincon sodium is an excellent colorimetric reagent for the detection of zinc and copper ions in aqueous solution. Zincon sodium can be used for the determination of zinc, copper, and cobalt ions in metalloproteins [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 62625-22-3. Pack Sizes: 1 g; 5 g; 10 g. Product ID: HY-D0813. | |
| Zinc Protoporphyrin | Zinc Protoporphyrin (Zn(II)-protoporphyrin IX) is an orally active and competitive heme oxygenase-1 (HO-1) inhibitor and markedly attenuates the protective effects of Phloroglucinol (PG) against H 2 O 2 [1]. Zinc Protoporphyrin is used as a screening marker of iron deficiency in individual pregnant women and children, but also to assess population iron status in combination with haemoglobin concentration [2]. Zinc Protoporphyrin has anti-cancer activity [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Zn(II)-protoporphyrin IX; ZnPP; Zinc Protoporphyrin-9. CAS No. 15442-64-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-101193. | |
| Zinc Pyrithione | Zinc Pyrithione is an antifungal and antibacterial agent disrupting membrane transport by blocking the proton pump [1]. Zinc Pyrithione is also a copper ionophore that delivers copper into cells and is a useful tool for studying cuproptosis [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 13463-41-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0572. | |
| Zinc sulfate heptahydrate | Zinc sulfate heptahydrate is a hydrate that is the heptahydrate form of zinc sulfate. Zinc sulfate heptahydrate is a dietary supplement used for zinc deficiency and to prevent the condition in those at high risk [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 7446-20-0. Pack Sizes: 10 mM * 1 mL; 10 g; 50 g; 100 g. Product ID: HY-N3025. | |
| Zinc sulfate monohydrate | Zinc sulfate monohydrate is a biochemical reagent. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 7446-19-7. Pack Sizes: 50 mg; 100 mg. Product ID: HY-W094709. | |
| Zinc sulphate | Zinc sulphate is a biological molecule. Uses: Scientific research. Group: Signaling pathways. CAS No. 7733-02-0. Pack Sizes: 25 g; 50 g; 100 g. Product ID: HY-B1820. | |
| Zinc trifluoromethanesulfonate | Zinc trifluoromethanesulfonate (Zinc(II) Triflate) is a biological molecule. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Zinc(II) Triflate. CAS No. 54010-75-2. Pack Sizes: 100 g; 500 g; 1000 g. Product ID: HY-21170E. | |
| Zineb | Zineb is an agricultural fungicide of the dithiocarbamate class. Its toxicity is relatively low, and there is little evidence of human harm from exposure. Oxidative stress is one of the main factors contributing to diseases caused by Zineb. Zineb does not alter the activity of any superoxide dismutase enzymes. Catalase (CAT) activity was reduced only by Zineb. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Zinc ethylene-1, 2-bisdithiocarbamate. CAS No. 12122-67-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-W127739. | |
| Zingerone | Zingerone (Vanillylacetone) is a nontoxic methoxyphenol isolated from Zingiber officinale , with potent anti-inflammatory, antidiabetic, antilipolytic, antidiarrhoeic, antispasmodic and anti-tumor [3] properties [1]. Zingerone alleviates oxidative stress and inflammation, down-regulates NF-κB mediated signaling pathways [2]. Zingerone acts as an anti-mitotic agent, and inhibits the growth of neuroblastoma cells [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Vanillylacetone; Gingerone. CAS No. 122-48-5. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-14621. | |
| Zingiberene | Zingiberene (α-Zingiberene) is a monocyclic sesquiterpene which is the predominant constituent of ginger with oil content ( Zingiber officinale ). Neuroprotective potential [1]. Zingiberene triggers autophagy. Anticancer activity [2]. Uses: Scientific research. Group: Natural products. Alternative Names: α-Zingiberene; (-)-Zingiberene. CAS No. 495-60-3. Pack Sizes: 500 μg. Product ID: HY-14618. | |
| Zinlirvimab | Zinlirvimab is a human IgG1-λ2, HIV neutralising antibody targeting to HIV-1 gp120 envelope glycoprotein (IIIB gp120 V3 loop) [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: 10-1074. CAS No. 2417213-75-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99102. | |
| Zinpyr-1 | Zinpyr-1 is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Fluorescent dye. CAS No. 288574-78-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-D0155. | |
| Zinquin | Zinquin is a fluorescent sensor and used to observe reactive Zn 2+.λex/λem=368/490 nm. Uses: Scientific research. Group: Fluorescent dye. CAS No. 151606-29-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-D0982. | |
| Zinquin ethyl ester | Zinquin ethyl ester is a fluorescent derivative of Zinquin and is a fluorescent probe of cytosolic zinc ion. Zinquin ethyl ester is able to penetrate cell membranes and is lipophilic and zinc-sensitive. Zinquin ethyl ester can combine with Zn 2+ in the cell to produce blue fluorescence [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 181530-09-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-124171. | |
| Zinterol hydrochloride | Zinterol hydrochloride (MJ 9184 hydrochloride) is a potent and selective β2-adrenoceptor agonist [1]. Zinterol hydrochloride increases I Ca in a concentration-dependent manner with an EC 50 of 2.2 nM [2]. Zinterol hydrochloride induces ventricular arrhythmias in conscious heart failure rabbits [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MJ 9184 hydrochloride. CAS No. 38241-28-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-14304A. | |
| ZIP | ZIP is a selective peptide inhibitor of PKM&zeta. ZIP injections can block the impairment in morphine conditioned place preference induced [1]. Uses: Scientific research. Group: Peptides. CAS No. 863987-12-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1284. | |
| Zipalertinib | Zipalertinib (TAS6417; CLN-081) is a highly effective, orally active and pan-mutation-selective EGFR tyrosine kinase inhibitor with a unique scaffold fitting into the ATP-binding site of the EGFR hinge region, with IC 50 values ranging from 1.1-8.0 nM [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TAS6417; CLN-081. CAS No. 1661854-97-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112299. | |
| Ziprasidone | Ziprasidone (CP-88059), an orally active antipsychotic agent, is a combined 5-HT and dopamine receptor antagonist [1]. Ziprasidone mesylate trihydrate has affinities for Rat D 2 ( K i =4.8 nM), 5-HT 2A ( K i =0.42 nM) and 5-HT 1A ( K i =3.4 nM) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CP-88059. CAS No. 146939-27-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-14542. | |
| Ziprasidone hydrochloride monohydrate | Ziprasidone (CP-88059) hydrochloride monohydrate is an orally active combined 5-HT and dopamine receptor antagonist [1]. Ziprasidone hydrochloride monohydrate has affinities for Rat D 2 ( K i =4.8 nM), 5-HT 2A ( K i =0.42 nM) and 5-HT 1A ( K i =3.4 nM) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CP 88059 hydrochloride monohydrate. CAS No. 138982-67-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-17407. | |
| Ziresovir | Ziresovir (AK0529;RO-0529) is a potent, selective, and orally bioavailable respiratory syncytial virus (RSV) fusion (F) protein ( RSV F ) protein inhibitor. Ziresovir shows anti-RSV activity ( EC 50 =3 nM) and highlights pharmacokinetics in animal species [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AK0529; RO-0529. CAS No. 1422500-60-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109142. | |
| Ziritaxestat | Ziritaxestat (GLPG1690) is a first-in-class autotaxin (ATX) inhibitor, with an IC 50 of 131 nM and a K i of 15 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GLPG1690. CAS No. 1628260-79-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101772. | |
| Ziv-aflibercept | Ziv-aflibercept is a soluble inhibitor of vascular endothelial growth factor ( VEGF ). Ziv-aflibercept is an adaptive variant of Aflibercept (HY-108801), Ziv-aflibercept has a low PH value and high osmotic pressure when compared to Aflibercept. Ziv-aflibercept has potential applications in metastatic colorectal carcinoma and retinal diseases [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1609655-49-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-108798. | |
| (Z)-JQ1-TCO | JQ1-TCO (JQ1- trans -cyclooctene) is a derivative of JQ1 (HY-13030), an inhibitor of BET. JQ1-TCO is suitable for click chemistry and can be used as molecular probes in vitro and in vivo [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2087490-43-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148864A. | |
| ZK 93423 | ZK 93423 is a potent benzodiazepine GABAA receptor agonist with a certain cooling effect on rodents [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 83910-44-5. Pack Sizes: 1 mg. Product ID: HY-116813. | |
| ZL006 | ZL006 is a potent inhibitor of nNOS/PSD-95 interaction, and inhibits NMDA receptor -mediated NO synthesis. Uses: Scientific research. Group: Signaling pathways. CAS No. 1181226-02-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100456. | |
| ZL-2201 | ZL-2201 is a potent DNA-PK inhibitor with an IC 50 of 1 nM (WO2021104277A1, compound 5) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2865115-39-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-142471A. | |
| Z-Leu-Arg-AMC | Z-Leu-Arg-AMC is a 4-methylcoumarinyl-7-amide (Amc) leucine derivative with carboxybenzoyl (Z). Z-Leu-Arg-AMC is the active site of cysteine proteinase trypanopain-Tb from Trypanosoma brucei brucei [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 156192-32-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-142021. | |
| Z-Leu-Leu-Glu-AMC | Z-Leu-Leu-Glu-AMC is a substrate peptide, and can be used for determination of postacidic-like hydrolysing activity of 20S proteasome [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Z-LLE-AMC. CAS No. 348086-66-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-123053. | |
| (Z)-Ligustilide | (Z)-Ligustilide is extracted from Ligusticum chuanxiong Hort, has antimicrobial and antifungal activity, exhibits an average antifungal score of 5.6 [1]. (Z)-Ligustilide is orally active, it inhibits the expression of FATP5 and DGAT, inhibits fatty acid uptake and esterification in mice and has potential as therapeutics for nonalcoholic fatty liver disease (NAFLD) [2]. (Z)-Ligustilide is also able to reactivate ERα, has epigenetic regulation, and is used in the study of tamoxifen-resistant breast cancer [3]. Uses: Scientific research. Group: Natural products. CAS No. 81944-09-4. Pack Sizes: 5 mg; 10 mg; 20 mg. Product ID: HY-N0401A. | |
| (Z-LL)2 ketone | (Z-LL)2 ketone is an inhibitor of ketone with an IC 50 value of 50 nM. (Z-LL)2 ketone promotes the release of an N-terminal fragment into the cytosol [1]. Uses: Scientific research. Group: Peptides. CAS No. 313664-40-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1425. | |
| ZLN024 hydrochloride | ZLN024 hydrochloride is an AMPK allosteric activator. ZLN024 directly activates recombinant AMPK α1β1γ1, AMPK α2β1γ1, AMPK α1β2γ1 and AMPK α2β2γ1 heterotrimer with EC 50 s of 0.42 μM, 0.95 μM, 1.1 μM and 0.13 μM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1883548-91-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16708A. | |
| Z-L-Val-OH | Z-L-Val-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: N-Cbz-L-valine. CAS No. 1149-26-4. Pack Sizes: 25 g. Product ID: HY-W008753. | |
| Z-Lys-OH | Z-Lys-OH is a lysine derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 2212-75-1. Pack Sizes: 10 g; 25 g; 100 g; 500 g. Product ID: HY-W009337. | |
| ZM323881 hydrochloride | ZM323881 hydrochloride is a potent and selective VEGFR2 inhibitor with an IC 50 of less than 2 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 193000-39-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15467A. | |
| ZM 336372 | ZM 336372 is a potent inhibitor of the protein kinase c-Raf. The IC 50 value is 0.07 μM in the standard assay, which contains 0.1 mM ATP. Uses: Scientific research. Group: Signaling pathways. CAS No. 208260-29-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-13343. | |
| ZM-447439 | ZM-447439 is an aurora kinase inhibitor with IC 50 s of 110 and 130 nM for aurora A and B, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 331771-20-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10128. | |
| ZM 449829 | ZM 449829 is a potent, selective and ATP competitive inhibitor of JAK3 , with a pIC 50 of 6.8. ZM 449829 will be useful pharmacological tools for the investigation of the JAK3 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 4452-6-6. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-13450. | |
| Zn(II) Mesoporphyrin IX | Zn(II) Mesoporphyrin IX (ZnMP) is a specific activator of ABCB10 , significantly increasing its ATPase activity and acting as a substrate for ABCB10 in heme synthesis. Zn(II) Mesoporphyrin IX may promote the transcription of hemoglobinization genes by facilitating the degradation of the Bach1 repressor. Zn(II) Mesoporphyrin IX aids in studying the potential roles of ABCB10 in heme synthesis, oxidative stress protection, hepatitis C, and other areas [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: ZnMP. CAS No. 14354-67-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-W583212. | |
| Zofenopril | Zofenopril is an angiotensin-converting enzyme ( ACE ) inhibitor with an IC 50 of 81 μM. Uses: Scientific research. Group: Signaling pathways. CAS No. 81872-10-8. Pack Sizes: 5 mg. Product ID: HY-108321. | |
| Zofenopril calcium | Zofenopril Calcium (SQ26991) is an orally active angiotensin-converting enzyme ( ACE ) inhibitor with antioxidant activity and cardioprotective effects. Zofenopril Calcium reduces ROS production and GSH consumption and helps inhibit foam cell formation, thus slowing the progression of atherosclerosis. Zofenopril Calcium prevents cardiac damage caused by chronic Doxorubicin (HY-15142A). Uses: Scientific research. Group: Signaling pathways. Alternative Names: SQ26991. CAS No. 81938-43-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0655. | |
| Zolbetuximab | Zolbetuximab (IMAB362) is a monoclonal antibody targeting Claudin-18.2. Zolbetuximab mediates specific killing of Claudin-18.2-positive cells through immune effector mechanisms. Zolbetuximab can be used for the research of gastrointestinal adenocarcinomas and pancreatic tumors [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: IMAB362. CAS No. 1496553-00-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99058. | |
| Zoldonrasib | RMC-9805 (KRAS G12D inhibitor 18) is a potent and orally active KRAS G12D inhibitor. RMC-9805 induces apoptosis in KRAS G12D mutant cancer cells. RMC-9805 has the potential for the research of KRAS G12D mutant cancer [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RMC-9805; KRAS G12D inhibitor 18. CAS No. 2922732-54-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156819. | |
| Zoledronic Acid | Zoledronic Acid (Zoledronate) is a third-generation bisphosphonate (BP), with potent anti-resorptive activity. Zoledronic Acid inhibits the differentiation and apoptosis of osteoclasts. Zoledronic Acid also has anti-cancer effects [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Zoledronate; CGP 42446; CGP42446A; ZOL 446. CAS No. 118072-93-8. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-13777. | |
| Zoledronic acid monohydrate | Zoledronic acid monohydrate (Zoledronate monohydrate) is a third-generation bisphosphonate (BP), with potent anti-resorptive activity. Zoledronic acid monohydrate inhibits the differentiation and apoptosis of osteoclasts. Zoledronic acid monohydrate also has anti-cancer effects [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Zoledronate monohydrate; CGP 42446 monohydrate; CGP42446A monohydrate; ZOL 446 monohydrate. CAS No. 165800-06-6. Pack Sizes: 50 mg; 100 mg. Product ID: HY-13777A. | |
| Zoliflodacin | Zoliflodacin (ETX0914;AZD0914) is a novel spiropyrimidinetrione bacterial DNA gyrase/topoisomerase inhibitor. Zoliflodacin has potent in vitro antibacterial activity against Gram-positive and Gram-negative organisms, including S. aureus with the MIC 90 of 0.25 μg/mL. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ETX0914; AZD0914. CAS No. 1620458-09-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17647. | |
| Zolimidine | Zolimidine, a derivate of imidazopyridine, is an orally active antiulcer agent. Zolimidine stimulates mucus secretion in intestinal mucosal cells and enhacnes intestinal wall more resistant to ulceration. Zolimidine exhibits gastroprotective effect in duodenal ulcer research [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1222-57-7. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-108278. | |
| Zolmitriptan | Zolmitriptan (BW-311C90; 311C90) is a 5-HT1B/1D receptor partial agonist with K i s of 5.01 nM, 0.63 nM, and 63.09 nM for 5-HT1B, 5-HT1D, 5-HT1F receptor, respectively. Zolmitriptan can be used for the research of migraine [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: BW-311C90; 311C90. CAS No. 139264-17-8. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg. Product ID: HY-B0229. | |
| Zomiradomide | KT-413 (example I-3) is an orally active PROTAC-class IRAK degrader [1]. KT-413 consists of a target protein ligand (red part) PROTAC IRAK4 ligand-5 (HY-168311), an E3 ubiquitin ligase ligand (blue part) Thalidomide-4-Br (HY-W039116), and a PROTAC linker (black part) 2-(2-Azaspiro[3.3]heptan-6-yl)ethanamine (HY-168313). E3 ubiquitin ligase and linker can form Thalidomide-NH-C2-2-azaspiro[3.3]heptane (HY-168312). The active control for the target protein ligand is RSL3-4-Me (HY-169375). Uses: Scientific research. Group: Signaling pathways. Alternative Names: KT-413. CAS No. 2655656-99-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153368. | |
| Zongertinib | Zongertinib (BI 1810631) is a potent and selective HER2 and EGFR tyrosine kinase inhibitor with IC 50 values of 13 nM and 579 nM, respectively. Zongertinib has antitumor activity and can be used in the study of multiple solid tumors [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BI 1810631. CAS No. 2728667-27-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-148810. | |
| Zoniporide | Zoniporide (CP-597396) is a potent and selective NHE-1 inhibitor with cardioprotective activity. Zoniporide inhibits 22 Na + uptake by human NHE-1 -expressing fibroblasts in a concentration-dependent manner ( IC 50 =14 nM). Zoniporide inhibits platelet swelling in vitro with an IC 50 of 0.059 μM. Zoniporide can be used in the study of cardiovascular disease [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CP-597396. CAS No. 241800-98-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-105064. | |
| Zoniporide hydrochloride hydrate | Zoniporide (CP-597396) hydrochloride hydrate is a potent and selective inhibitor of sodium-hydrogen exchanger type 1 (NHE-1). Zoniporide hydrochloride hydrate inhibits human NHE-1 ( IC 50=14 nM), and has >150-fold selectivity versus other NHE isoforms. Zoniporide hydrochloride hydrate potently inhibits ex vivo NHE-1-dependent swelling of human platelets (IC 50 =59 nM) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CP-597396 hydrochloride hydrate. CAS No. 863406-85-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-105064D. | |
| Zonisamide | Zonisamide (AD 810) is an orally active carbonic anhydrase inhibitor, with K i s of 35.2 and 20.6 nM for hCA II and hCA V , respectively. Zonisamide exerts neuroprotective effects through anti- apoptosis and upregulating MnSOD levels. Zonisamide also increases the expression of Hrd1 , thereby improving cardiac function in AAC rats. Zonisamide can be used in studies of seizure, parkinsons disease and cardiac hypertrophy [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AD 810; CI 912. CAS No. 68291-97-4. Pack Sizes: 10 mM * 1 mL; 200 mg; 500 mg. Product ID: HY-B0124. | |
| Zorifertinib | Zorifertinib (AZD3759) is a potent, orally active, central nervous system-penetrant, EGFR inhibitor. At K m ATP concentrations, the IC 50 s are 0.3, 0.2, and 0.2 nM for EGFR wt , EGFR L858R , and EGFR exon 19Del , respectively. Zorifertinib induces cancer cell apoptosis. Zorifertinib has antitumor activity, and can be used for NSCLC, HCC etc. research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AZD3759. CAS No. 1626387-80-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18750. | |
| Zosuquidar | Zosuquidar (LY335979) is a P-glycoprotein (P-gp) inhibitor ( K i =59 nM). Zosuquidar shows anti-tumor activities, and can be used in acute myelogenous leukemia (AML) research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RS 33295-198; LY-335979. CAS No. 167354-41-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-15255. | |
| Zosurabalpin | Zosurabalpin is a polypeptide antibiotic targeting LPS transporter (LptB 2 FGC complex), which can block the transport of LPS and lead to endotoxin accumulation in cells, and has shown excellent antibacterial activity against Carbapenem-resistant Acinetobacter baumanni (CRAB) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Abx MCP; RG6006. CAS No. 2379336-76-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147429. | |
| Zotarolimus | Zotarolimus (ABT-578) is a derivative of Rapamycin (HY-10219), with anti-proliferative activity. Zotarolimus is an immunosuppressant. Zotarolimus is developed specifically for local delivery from stents for the prevention of coronary artery restenosis [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABT-578; A 179578. CAS No. 221877-54-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-12424. | |
| Zotatifin | Zotatifin (eFT226) is a potent, selective, and well-tolerated eIF4A inhibitor. Zotatifin promotes eIF4A binding to specific mRNA sequences with recognition motifs in the 5-UTRs ( IC 50 =2 nM) and interferes with the assembly of the eIF4F initiation complex [1]. Zotatifin shows robust antiviral effects, it effectively reduces viral infectivity by inhibiting SARS-CoV-2 NP protein biogenesis ( IC 90 =37 nM) [2]. Zotatifin induces cell apoptosis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: eFT226. CAS No. 2098191-53-6. Pack Sizes: 1 mg; 2 mg; 5 mg; 10 mg. Product ID: HY-112163. | |
| Zotepine | Zotepine, an antipsychotic agent, is a potent antagonist of 5-HT 2A , 5-HT 2C , Histamine H 1 , α 1 -adrenergic and Dopamine D 2 receptors , with K d s of 2.6 nM, 3.2 nM, 3.3 nM, 7.3 nM and 8 nM, respectively. Zotepine exhibits antidepressive and anxiolytic effects in vivo [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 26615-21-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-103093. | |
| Zotizalkib | Zotizalkib (TPX-0131) is a potent, selective, CNS-penetrant and orally active inhibitor of wild-type ALK ( IC 50 of 1.4 nM) and ALK-resistant mutation , e.g. G1202R ( IC 50 of 0.3 nM), L1196M ( IC 50 of 0.3 nM). Zotizalkib has strong antitumor activities [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TPX-0131. CAS No. 2648641-36-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-139279. | |
| Zoxazolamine | Zoxazolamine is widely used for a pharmacologic test that serves as a convenient indicator of changes in cytochrome P-450 activity in rodents. Uses: Scientific research. Group: Signaling pathways. CAS No. 61-80-3. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B1307. | |
| Z-Phe-Leu-Glu-pNA | Z-Phe-Leu-Glu-pNA is a chromogenic substrate for glutamyl endopeptidases. Z-Phe-Leu-Glu-pNA has been used as a synthetic substrate in the study of proteolytic enzymes, including trypsin treatment, subtilisin and chymotrypsin. Z-Phe-Leu-Glu-pNA plays an important role in hormone disorders such as prostate cancer and breast cancer [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 104634-10-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P4516. | |
| Z-Pyr-OH | Z-Pyr-OH (Cbz-L-pyroglutamic acid) can be used as a biochemical assay reagent [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Cbz-L-pyroglutamic acid. CAS No. 32159-21-0. Pack Sizes: 25 g; 50 g; 100 g. Product ID: HY-W011750. | |
Would you like to list your products on USA Chemical Suppliers?
Our database is helping our users find suppliers everyday.