MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| VU0364770 hydrochloride | VU0364770 hydrochloride is a selective and potent positive allosteric modulator ( PAM ) of mGlu4. VU0346770 hydrochloride exhibits EC 50 s of 290 nM and 1.1 μM at rat mGlu4 and human mGlu4 receptor , respectively. VU0364770 hydrochloride exhibits antagonist activity at mGlu5 with a potency of 17.9 μM and PAM activity at mGlu6 with a potency of 6.8 μM. VU0364770 hydrochloride also possesses activity at MAO with K i values of 8.5 and 0.72 μM for human MAO-A and human MAO-B, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1414842-70-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100588A. |  |
| VU0486321 | VU0486321 is a compound in a class of mGlu1 positive allosteric modulators (PAMs). VU0486321 maintains acceptable mGlu1 PAM potency, DMPK profile, CNS permeability, and mGluR selectivity. Uses: Scientific research. Group: Signaling pathways. CAS No. 1816301-67-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-118179. | |
| VU0486846 | VU0486846 is an orally active and selective muscarinic acetylcholine receptor M1 positive allosteric modulator (PAM) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1788055-11-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-121806. | |
| VU-29 | VU-29 is a positive allosteric modulator of metabotropic glutamate 5 (mGlu5) receptor ( EC 50 =9 nM and K i =244 nM for rmGluR5). VU-29 is selective for mGluR5 relative to other mGluR subtypes (EC 50 : rmGluR1/rmGluR2=557 nM/1.5 μM; hmGluR4=154 nM) [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 890764-36-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107508. | |
| VU590 | VU590 is a potent and moderately selective ROMK (Kir1.1) inhibitor, with an IC 50 of 290 nM. VU590 also inhibits Kir7.1 , with an IC 50 of 8 μM. VU590 is not a good probe of ROMK function in the kidney [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 313505-85-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108595. | |
| VU6036720 | VU6036720 is a potent and specific in vitro inhibitor of Kir4.1/5.1. VU6036720 can inhibit Kir4.1/5.1 channels with an IC 50 value of 0.24 μM. VU6036720 can be used for the research of brain and kidney [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3026597-12-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-148304. | |
| Vudalimab | Vudalimab is a potent dual PD-1 and CTLA-4 inhibitor as a fully humanized bispecific monoclonal antibody. Vudalimab targets immune checkpoint receptors PD-1 and CTLA-4 and promotes tumor-selective T-cell activation [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2329669-72-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99166. | |
| VUF10166 | VUF10166 is a potent and high-affinity 5-HT 3 receptor antagonist, with K i values of 0.04 nM (5-HT 3 A) and 22 nM (5-HT 3 AB). VUF10166 inhibits 5-HT-induced responses at 5-HT 3 A and 5-HT 3 AB receptors at nanomolar concentrations. At 5-HT 3 receptor , VUF10166 at higher concentrations also acts as a partial agonist, with an EC 50 of 5.2 μM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 155584-74-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100552. | |
| VUF 8430 dihydrobromide | VUF 8430 (dihydrobromide) is a potent and selective histamine H4 receptor agonist with a K i of 31.6 nM and an EC 50 of 50 nM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 100130-32-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-107555. | |
| Vunakizumab | Vunakizumab (Anti-Human IL17A Recombinant Antibody) is a recombinant human IgGκ monoclonal antibody that targets IL-17A and inhibits its interaction with the IL-17 receptor. Vunakizumab can be used to study autoimmune diseases such as psoriatic arthritis, ankylosing spondylitis, multiple sclerosis and inflammatory arthritis [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-Human IL17A Recombinant Antibody. CAS No. 1792181-33-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99335. | |
| VUT-MK142 | VUT-MK142 is a potent new cardiomyogenic synthetic agent promoting the differentiation of pre-cardiac mesoderm into cardiomyocytes, which may be useful to differentiate stem cells into cardiomyocytes for cardiac repair [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1313491-22-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122610. | |
| W-13 hydrochloride | W-13 hydrochloride is a calmodulin antagonist. W-13 hydrochloride can inhibit Tamoxifen (HY-13757A)-resistant human breast cancer cell growth [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 88519-57-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100910. | |
| W-5 hydrochloride | W-5 hydrochloride is a calmodulin antagonist. W-5 hydrochloride inhibits phosphodiesterase activation with an IC 50 value of 240 μM. W-5 hydrochloride can be used as a negative control for W-7 (HY-100912) [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 61714-25-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100911. | |
| W-7 hydrochloride | W-7 hydrochloride is a selective calmodulin antagonist. W-7 hydrochloride inhibits the Ca 2+ -calmodulin -dependent phosphodiesterase and myosin light chain kinase with IC 50 values of 28 μM and 51 μM, respectively [1] [2]. W-7 hydrochloride induces apoptosis and has antitumor activity [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 61714-27-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100912. | |
| W-84 dibromide | W-84 (dibromide) is a potent allosteric modulator of M2-cholinoceptors , which retards [ 3 H]N-methylscopolamine dissociation. W-84 dibromide can stabilize cholinergic antagonist-receptor complexes. W-84 (dibromide) is a non-competitive muscarinic acetylcholine receptors antagonist with allosteric effects. W-84 (dibromide) protects over additively against an organophosphate-intoxication when applied in combination with atropine [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HDMPPA. CAS No. 21093-51-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100979. | |
| Water-17O | Water- 17 O is the 17 O labeled Water [1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 13768-40-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108872S1. | |
| Water-18O | Water- 18 O is the 18 O-labeled Water [1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 14314-42-2. Pack Sizes: 100 mg; 250 mg. Product ID: HY-108872S. | |
| Watermelon ketone | Watermelon ketone is fragrance chemical compound with special odorant which has been widely used in the fragrance industry, extracted from patent CN 103058984 A. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 7-Methyl-2H-1,5-benzodioxepin-3(4H)-one. CAS No. 28940-11-6. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-W016622. | |
| WAY-100135 dihydrochloride | WAY-100135 dihydrochloride is a selective antagonist at presynaptic and postsynaptic 5-HT 1A receptor, with an IC 50 of 34 nM at the rat hippocampal 5-HT 1A receptor. WAY-100135 dihydrochloride has potential antipsychotic properties [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 149055-79-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-117575A. | |
| WAY-100635 | WAY-100635 is a potent and selective 5-HT 1A Receptor antagonist with a pIC 50 of 8.87, an apparent pA 2 of 9.71. WAY-100635 is a potent and selective 5-hydroxytryptamine 1A (5-HT1A) receptor antagonist with an IC 50 value of 0.91 nM and K i value of 0.39 nM. WAY-100635 has pIC 50 values for 5-HT1A and α1-adrenergic receptors of 8.9 and 6.6, respectively. WAY-100635 is also a potent dopamine D 4 receptor agonist [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 162760-96-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10349. | |
| WAY-100635 maleate | WAY-100635 maleate is a potent and selective 5-hydroxytryptamine 1A (5-HT1A) receptor antagonist with an IC 50 value of 0.91 nM and K i value of 0.39 nM. WAY-100635 maleate has pIC 50 values for 5-HT1A and α1-adrenergic receptors of 8.9 and 6.6, respectively. WAY-100635 maleate is also a potent dopamine D 4 receptor agonist [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1092679-51-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10349A. | |
| WAY-181187 | WAY-181187 (SAX-187) is a potent and selective full 5-HT6 receptor agonist with a K i of 2.2 nM and an EC 50 of 6.6 nM [1]. WAY181187 mediates 5-HT6 receptor-dependent signal pathways, such as cAMP, Fyn and ERK1/2 kinase, as specific agonist [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SAX-187. CAS No. 554403-49-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-14340. | |
| WAY-200070 | WAY-200070 is a selective estrogen receptor β ( ERβ ) agonist with an IC 50 of 2.3 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 440122-66-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101271. | |
| WAY208466 dihydrochloride | WAY 208466 dihydrochloride is a potent and selective 5-HT 6 receptor agonist ( EC 50 =7.3 nM for the human 5-HT 6 receptor). WAY-208466 dihydrochloride elevates cortical GABA levels in rat frontal cortex [1]. WAY 208466 dihydrochloride exhibits antidepressant and anxiolytic-like effects [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1207064-61-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-103133. | |
| WAY-262611 | WAY-262611 is a Wnt / β-Catenin agonist that increases bone formation rate with an EC 50 of 0.63 μM in TCF-Luciferase assay. WAY-262611 is also a Dkk1 inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1123231-07-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-11035. | |
| WAY-621089 | WAY-621089 is an active molecule for the study of amyloid diseases and synucleinopathies [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 303790-92-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-47595. | |
| Wedelolactone | Wedelolactone suppresses LPS-induced caspase-11 expression by directly inhibits the IKK Complex. Wedelolactone also inhibits 5-lipoxygenase ( 5-Lox ) with an IC 50 of 2.5 μM. Wedelolactone induces caspase-dependent apoptosis in prostate cancer cells via downregulation of PKCε without inhibiting Akt. Wedelolactone can extract from Eclipta alba, and it can be used for the research of cancer [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 524-12-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0551. | |
| WEHI-345 | WEHI-345 is a potent and selective RIPK2 kinase inhibitor with an IC 50 of 0.13 μM, which delays RIPK2 ubiquitylation and NF-κB activation on oligomerization domain (NOD) stimulation [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1354825-58-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18937. | |
| WEHI-345 analog | WEHI-345 analog is the analog of WEHI-345. WEHI-345 is a potent and selective RIPK2 kinase inhibitor with an IC 50 of 0.13 μM, which delays RIPK2 ubiquitylation and NF-κB activation on oligomerization domain (NOD) stimulation [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1354825-62-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-100112. | |
| Werner syndrome RecQ helicase-IN-4 | Werner syndrome RecQ helicase-IN-4 is a potent and orally active werner syndrome recQ helicase (WRN) inhibitor with an IC 50 value of 0.06 μM. Werner syndrome RecQ helicase-IN-4 shows antiproliferative activity. Werner syndrome RecQ helicase-IN-4 shows anticancer activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2869954-53-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-148741. | |
| WH-15 | WH-15 is a fluorogenic PLC reporter with K m value of 49; 30, 86.1 μM for PLC-γ1, PLC-δ1, PLC-β2, respectively. WH-15 can be cleaved in a cascade reaction to generate fluorescent 6-aminoquinoline. WH-15 can be used to respond to imaging PLC activity in live cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1264748-47-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-135799. | |
| WHI-P180 | WHI-P180 (Janex 3) is a multi-kinase inhibitor; inhibits RET , KDR and EGFR with IC 50 s of 5 nM, 66 nM and 4 μM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Janex 3. CAS No. 211555-08-7. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15769. | |
| White mineral oil | White mineral oil is the highly refined mineral oil, and is composed of saturated aliphatic and alicyclic nonpolar hydrocarbons. White mineral oil is biologically and chemically stable, and doesnt support pathogenic bacterial growth. White mineral oil can resist moisture, extend, soften, smoothen, and lubricate [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Paraffin oil. CAS No. 8042-47-5. Pack Sizes: 5 mL. Product ID: HY-139411. | |
| Win 18446 | Win 18446 is an orally active testes-specific enzyme ALDH1a2 inhibitor, with an IC 50 of 0.3 μM. Win 18446 reversibly inhibits spermatogenesis in many species and inhibits Retinoic acid (HY-14649) biosynthesis from Retinol (HY-B1342) within the testes [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1477-57-2. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-W011094. | |
| Withaferin A | Withaferin A is a steroidal lactone isolated from Withania somnifera , inhibits NF-kB activation and targets vimentin , with potent antiinflammatory and anticancer activities. Withaferin A is an inhibitor of endothelial protein C receptor (EPCR) shedding. Uses: Scientific research. Group: Natural products. CAS No. 5119-48-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg. Product ID: HY-N2065. | |
| Withanolide A | Withanolide A is an orally active extract from the Indian herb Ashwagandha. Withanolide A can induce apoptosis. Withanolide A has anti-inflammatory and antitumor activity. Withanolide A can be used in the study of neurodegenerative diseases [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 32911-62-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N7028. | |
| Withanone | Withanone is an active constituent from Withania somnifera roots with multifunctional neuroprotective effect in alleviating cognitive dysfunction. Withanone affords protection against N-methyl-D-aspartate (NMDA) -induced excitotoxicity in Neuron-like cells [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 27570-38-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-129692. | |
| WM-662 | WM-662 is a WDR5-MYC interaction inhibitor, with an IC 50 of 18 μM. WM-662 has potential for the research of cancer, aging, and neurodegenerative disorders [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1308257-47-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-154847. | |
| Wnt-C59 | Wnt-C59 (C59) is a highly potent and oral porcupine (PORCN) inhibitor with an IC 50 of 74 pM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: C59. CAS No. 1243243-89-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15659. | |
| WNTinib | WNTinib (APS-8-100-2) is a multi-kinase inhibitor that selectively antagonizes β-catenin (CTNNB1) mutated hepatocellular carcinoma (HCC). WNTinib downregulates oncogenic Wnt signaling by inhibiting KIT/MAPK and downstream EZH2 activation [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: APS-8-100-2. CAS No. 2770091-44-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-160765. | |
| Wnt pathway inhibitor 3 | Wnt pathway inhibitor 3 is a potent wnt inhibitor with an IC 50 value of 45 nM. Wnt pathway inhibitor 3 shows antiproliferative activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 663213-98-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-153750. | |
| Wnt pathway inhibitor 4 | Wnt pathway inhibitor 4 (compound 16D) is an anticancer agent that has anti-proliferative activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 663214-57-1. Pack Sizes: 10 mg. Product ID: HY-153753. | |
| Wogonin | Wogonin is a naturally occurring mono-flavonoid, can inhibit the activity of CDK8 and Wnt , and exhibits anti-inflammatory and anti-tumor effects. Uses: Scientific research. Group: Natural products. CAS No. 632-85-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-N0400. | |
| Wogonoside | Wogonoside, a flavonoid glycoside isolated from Huangqin, possesses anti-inflammatory effects. Wogonoside induces autophagy in breast cancer cells by regulating MAPK-mTOR pathway [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 51059-44-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 20 mg. Product ID: HY-N0399. | |
| Wortmannin | Wortmannin (SL-2052; KY-12420) is a potent, selective and irreversible PI3K inhibitor with an IC 50 of 3 nM. Wortmannin also blocks autophagy formation, and potently inhibits Polo-like kinase 1 (PlK1) and Plk3 with IC 50 s of 5.8 and 48 nM, respectively [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: SL-2052; KY-12420. CAS No. 19545-26-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10197. | |
| WP1066 | WP1066 is an inhibitor of JAK2 and STAT3 , and also shows effect on STAT5 and ERK1/2, without affecting JAK1 and JAK3. Uses: Scientific research. Group: Signaling pathways. CAS No. 857064-38-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15312. | |
| WP9QY | WP9QY, TNF-a Antagonist, TNF-a Antagonist is a biological active peptide. (This cyclic peptide is designed to mimic the most critical tumor necrosis factor (TNF) recognition loop on TNF receptor I. It prevents interactions of TNF with its receptor. This TNF antagonist is a useful template for the development of small molecular inhibitors to prevent both inflammatory bone destruction and systemic bone loss in rheumatoid arthritis.). Uses: Scientific research. Group: Peptides. CAS No. 199999-60-5. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-P2612. | |
| Wright's stain | Wright's stain is a hematologic stain that facilitates the differentiation of blood cell types. Wright's stain is classically a mixture of eosin (red) and methylene blue dyes. It is used primarily to stain peripheral blood smears, urine samples, and bone marrow aspirates. Wright's stain provides a manual or automated stain for bone marrow and peripheral blood smears [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 68988-92-1. Pack Sizes: 5 g; 10 g. Product ID: HY-W088068. | |
| WRN inhibitor 8 | WRN inhibitor 8 (Example 224) is a WRN helicase inhibitor with IC 50 value of 48 nM. WRN inhibitor 8 can be used in cancer research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3026502-95-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-160859. | |
| WRW4 | WRW4, a specific formyl peptide receptor-like 1 (FPRL1) antagonist, inhibits WKYMVm binding to FPRL1 with an IC 50 of 0.23 μM. WRW4 specifically inhibits the increase in intracellular calcium by the FPRL1 agonists MMK-1, amyloid beta42 (Abeta42) peptide, and F peptide [1]. Uses: Scientific research. Group: Peptides. CAS No. 878557-55-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P1119. | |
| WS6 | WS6 is an IkB kinase and EBP1 inhibitor, with IC 50 values of 0.24 nM, 0.21 nM, and 40.48 nM in MV4-11, MOLM13, and K562 cells, respectively. WS6 promotes the proliferation of alpha and beta cells in the pancreas, has antioxidant and anti-inflammatory activities, and can alleviate depression like behavior in rats [1][2][4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1421227-53-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-12461. | |
| WST-1 | WST-1 is a kind of water-soluble tetrazolium salt. WST induces the intracellular mitochondrial dehydrogenase to conduct NADH-dependent enzyme digestion reaction, releasing the water-soluble methyl benzene product. WST-1 can be used for the detection of cell proliferation and cytotoxicity, via the determination of the light absorption value at 450 nm [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 150849-52-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136976. | |
| WST-3 | WST-3 is a water-soluble tetrazolium dye. In the presence of an electron mediator, WST-3 is reduced to WST-3 formazan by NADH and displays an absorption maxima of 433 nM [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 515111-36-1. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-125921. | |
| WST-8 | WST-8 is a water-soluble tetrazolium dye, WST-8 enhances sensitivity of the WST-8-based assay over the conventional MTS-based assay. Uses: Scientific research. Group: Fluorescent dye. CAS No. 193149-74-5. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-D0831. | |
| WZB117 | WZB117 is a glucose transporter 1 ( Glut1 ) inhibitor, which downregulates glycolysis, induces cell-cycle arrest, and inhibits cancer cell growth in vitro and in vivo. Uses: Scientific research. Group: Signaling pathways. CAS No. 1223397-11-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19331. | |
| X-34 | X-34 is a lipophilic and bright yellow-green fluorescent derivative of Congo red (HY-D0236). X-34 can be used to stain neuritic and diffuse plaques, neurofibrillary tangles (NFTs), neuropil threads, and cerebrovascular amyloid in the brain. X-34 can be used for research of Alzheimers disease [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 215294-98-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-125962. | |
| Xaliproden hydrochloride | Xaliproden hydrochloride (SR57746A) is a potent, selective and orally active agonist of 5-HT 1A receptor , shows a high affinity for 5-HT 1A specific binding sites in the rat hippocampus ( IC 50 =3 nM). Xaliproden hydrochloride is also a selective antagonist of dopamine D 2 receptor , has moderate affinity ( IC 50 =0.1-1 μM). Xaliproden hydrochloride exhibits anti-depression and anti-anxiety effects, and it may possess therapeutic potential for the research of neurodegenerative diseases [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SR57746A; SR57746 hydrochloride. CAS No. 90494-79-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14604. | |
| X-alpha-Gal | X-alpha-Gal is a chromogenic substrate that is used to screen colonies with high activity of β-galactopyranoside [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 107021-38-5. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114522. | |
| Xaluritamig | Xaluritamig is an anti- CD3E/STEAP1 monoclonal antibody [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2460399-39-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990688. | |
| Xamoterol hemifumarate | Xamoterol hemifumarate is a selective and potent agonist of beta1-adrenergic receptor. Xamoterol hemifumarate has the potential for the research of arrhythmogenesis. Xamoterol hemifumarate has the potential for the investigating the relationship between β1-adrenergic stimulation and IKr [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Corwin hemifumarate; ICI 118587 hemifumarate. CAS No. 73210-73-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101327A. | |
| Xanomeline | Xanomeline, as an effective and selective muscarinic type 1 and type 4 ( M1/M4 ) receptor agonist, increases neuronal excitability. Xanomeline can be used for the research of neurological disorders, such as schizophrenia [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY-246708. CAS No. 131986-45-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-105182. | |
| Xanomeline oxalate | Xanomeline oxalate (LY246708 oxalate) is a potent and selective muscarinic receptor agonist (SMRA) and stimulates phosphoinositide hydrolysis in vivo. Xanomeline oxalate can be used for the research of Alzheimers disease [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY246708 oxalate. CAS No. 141064-23-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13410. | |
| Xanomeline tartrate | Xanomeline (LY 246708) is the potent agonist of muscarinic M1/M4 receptor with antipsychotic-like activity. Xanomeline (LY 246708) increases neuronal excitability. Xanomeline (LY 246708) can be used for the research of schizophrenia [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY 246708 tartrate. CAS No. 152854-19-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-105182A. | |
| Xanthan gum | Xanthan gum is a microbial polysaccharide produced by Xanthomonas campestris. The structure of xanthan gum is based on a cellulose backbone of β-(1-4)-linked glucose units with a trisaccharide side of mannose-glucuronic acid-mannose attached to every other glucose unit in the backbone chain. Some terminal mannose units are pyruvated and some internal mannose units are acetylated. Due to its unique rheology and gelling properties, it is widely used as a food additive, thickener and stabilizer in the food and petroleum industries. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 11138-66-2. Pack Sizes: 500 g. Product ID: HY-A0103. | |
| Xanthine | Xanthine, a plant alkaloid found in tea, coffee, and cocoa, is a mild stimulant of the central nervous system. Xanthine also acts as an intermediate product on the pathway of purine degradation [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 69-89-6. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-W017389. | |
| Xanthine (Standard) | Xanthine (Standard) is the analytical standard of Xanthine. This product is intended for research and analytical applications. Xanthine, a plant alkaloid found in tea, coffee, and cocoa, is a mild stimulant of the central nervous system. Xanthine also acts as an intermediate product on the pathway of purine degradation [1] [2] [3]. In Vitro: A number of stimulants are derived from Xanthine including caffeine and theobromine. Xanthine is a product on the pathway of purine degradation. Xanthine is subsequently converted to uric acid by the action of the Xanthine oxidase enzyme. Uses: Scientific research. Group: Natural products. CAS No. 69-89-6. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-W017389R. | |
| Xanthinol Nicotinate | Xanthinol Nicotinate (Xanthinol Niacinate), a vasodilator, can act directly on the smooth muscle of small arteries and capillaries. Xanthinol Nicotinate expands blood vessels, improves blood rheology and reduces peripheral vascular resistance [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Xanthinol Niacinate. CAS No. 437-74-1. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-B1815. | |
| Xanthohumol | Xanthohumol is one of the principal flavonoids isolated from hops, the inhibitor of diacylglycerol acetyltransferase ( DGAT ), COX-1 and COX-2, and shows anti-cancer and anti-angiogenic activities. Xanthohumol also has antiviral activity against bovine viral diarrhea virus (BVDV) , rhinovirus , HSV-1 , HSV-2 and cytomegalovirus (CMV). Uses: Scientific research. Group: Natural products. CAS No. 6754-58-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-N1067. | |
| Xanthone | Xanthone is isolated from Mangosteen and is known to control cell division and growth, apoptosis, inflammation, and metastasis in different stages of carcinogenesis. Xanthone has anti-oxidant, anti-tumor, anti-allergic, anti-inflammatory, anti-bacterial, anti-fungal, and anti-viral activities [1]. Uses: Scientific research. Group: Natural products. CAS No. 90-47-1. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-N0126. | |
| Xanthone (Standard) | Xanthone (Standard) is the analytical standard of Xanthone. This product is intended for research and analytical applications. Xanthone is isolated from Mangosteen and is known to control cell division and growth, apoptosis, inflammation, and metastasis in different stages of carcinogenesis. Xanthone has anti-oxidant, anti-tumor, anti-allergic, anti-inflammatory, anti-bacterial, anti-fungal, and anti-viral activities [1]. Uses: Scientific research. Group: Natural products. CAS No. 90-47-1. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0126R. | |
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