MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Reproxalap | Reproxalap (ADX-102) is an active aldehyde sequestering agent that's being researched for dry eye syndrome, allergic conjunctivitis, and non-infectious anterior uveitis. Reproxalap has anti-inflammatory and pain-relieving effects [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ADX-102; NS-2. CAS No. 916056-79-6. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107150. |  |
| RepSox | RepSox (E-616452) is a potent and selective transforming growth factor-beta receptor I/activin like kinase 5 (TGF-β-RI/ALK5) inhibitor. RepSox inhibits ALK5 autophosphorylation with an IC 50 value of 4 nM. RepSox can be used for the research of obesity and associated metabolic diseases such as type 2 diabetes [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: E-616452; SJN 2511. CAS No. 446859-33-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13012. | |
| RepSox (GMP) | RepSox (E-616452) (GMP) is a RepSox (HY-13012) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. RepSox is a potent and selective TGF-?-RI/ALK5 inhibitor[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: E-616452 (GMP); SJN 2511 (GMP). CAS No. 446859-33-2. Pack Sizes: 10 mg; 50 mg; 100 mg. Product ID: HY-13012G. | |
| (R)-Equol | (R)-Equol is an agonist of both ERα and ERβ with K i s of 27.4 and 15.4 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (+)-Equol. CAS No. 221054-79-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-108414. | |
| Resatorvid | Resatorvid (TAK-242) is a selective Toll-like receptor 4 (TLR4) inhibitor. Resatorvid inhibits NO, TNF-? and IL-6 production with IC50s of 1.8 nM, 1.9 nM and 1.3 nM, respectively. Resatorvid downregulates expression of TLR4 downstream signaling molecules MyD88 and TRIF. Resatorvid inhibits autophagy and plays pivotal role in various inflammatory diseases[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TAK-242; CLI-095. CAS No. 243984-11-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-11109. | |
| Resazurin sodium | Resazurin sodium (Diazoresorcinol sodium) is a non-toxic, stable, membrane-permeable blue non-fluorescent dye (faintly fluorescent). Resazurin sodium is used as a redox indicator, can be reduced to pink, highly fluorescent Resorufin (Ex=530-560 nm, Em=590 nm) in living cells. Resazurin sodium can be used for the detection of cell viability, toxicity, proliferation, migration and invasion in cells (human, plant and animal, bacterial and fungal) [1] [2] [3]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Diazoresorcinol sodium. CAS No. 62758-13-8. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-111391. | |
| Resazurin (sodium), indicator | Resazurin sodium, indicator is a blue dye commonly used as a redox indicator in various chemical reactions, especially in microbiology and cell culture. Resazurin sodium, indicator has unique chemical properties that make it an effective tool for monitoring changes in the metabolic activity of cells and microorganisms. When reduced, Resazurin turns from blue to pink, providing a visual indication of metabolic activity. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Diazoresorcinol (sodium), indicator. CAS No. 62758-13-8. Pack Sizes: 1 g; 5 g. Product ID: HY-111391A. | |
| Reserpine | Reserpine is an inhibitor of the vesicular monoamine transporter 2 ( VMAT2 ). Uses: Scientific research. Group: Natural products. CAS No. 50-55-5. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-N0480. | |
| Reserpine hydrochloride | Reserpine hydrochloride is an inhibitor of the vesicular monoamine transporter 2 ( VMAT2 ). Uses: Scientific research. Group: Natural products. CAS No. 16994-56-2. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-N0480A. | |
| Resibufogenin | Resibufogenin is a component of cinobufogenin and has the function of inhibiting oxidative stress and tumor regeneration. Uses: Scientific research. Group: Natural products. Alternative Names: Bufogenin; Recibufogenin. CAS No. 465-39-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-N0815. | |
| Resigratinib | Resigratinib (KIN-3248) is an irreversible and orally active covalent inhibitor of FGFR1-4 that effectively inhibits wild-type and drug-resistant mutations (such as FGFR2 V565F, FGFR3 V555M). Resigratinib covalently binds to the Cys492 site of FGFR, blocks the FGFR signaling pathway, inhibits tumor cell proliferation and induces apoptosis. Resigratinib can be used for the study of FGFR2/3-driven solid tumors (such as cholangiocarcinoma and bladder cancer)[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KIN-3248. CAS No. 2750709-91-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156632. | |
| Resiniferatoxin | Resiniferatoxin ((+)-Resiniferatoxin), is a selective agonist of transient receptor potential vanilloid 1 (TRPV1) receptor agonist. Resiniferatoxin can be isolated from the Euphorbia resinifera plant. Resiniferatoxin eliminates TRPV1+ primary sensory afferents and blunt cardiac sympathetic afferent reflex for a relatively long period [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: (+)-Resiniferatoxin. CAS No. 57444-62-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N2333. | |
| Resiquimod | Resiquimod is a Toll-like receptor 7 and 8 ( TLR7/TLR8 ) agonist that induces the upregulation of cytokines such as TNF-α, IL-6 and IFN-&alpha. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R848; S28463. CAS No. 144875-48-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-13740. | |
| Reslizumab | Reslizumab (Sch 55700) is humanized monoclonal antibodies that target interleukin-5 (IL-5) for the treatment of eosinophilic asthma. Reslizumab is effective in neutralizing the function of IL-5. Reslizumab has high binding affinity for human IL-5 , with K D values of 109 pM and 4.3 pM in the the Biacore surface plasmon resonance and Kinetic Exclusion Assay, respectively [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Sch 55700. CAS No. 241473-69-8. Pack Sizes: 1 mg; 2 mg. Product ID: HY-P9949. | |
| Resmetirom | Resmetirom (MGL-3196) is a highly selective and orally active thyroid hormone receptor β ( THR-β ) agonist with an EC 50 value of 0.21 μM. Resmetirom can be used for the study of noncirrhotic nonalcoholic steatohepatitis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MGL-3196; VIA-3196. CAS No. 920509-32-6. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12216. | |
| Resminostat | Resminostat (RAS2410; 4SC-201) is a potent inhibitor of HDAC1 , HDAC3 and HDAC6 , with mean IC 50 values of 42.5, 50.1, 71.8 nM, respectively, and shows less potent activities against HDAC8, with an IC 50 of 877 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RAS2410; 4SC-201. CAS No. 864814-88-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14718. | |
| Resminostat hydrochloride | Resminostat hydrochloride is a potent inhibitor of HDAC1 , HDAC3 and HDAC6 , with mean IC 50 values of 42.5, 50.1, 71.8 nM, respectively, and shows less potent activities against HDAC8, with an IC 50 of 877 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RAS2410 hydrochloride; 4SC-201 hydrochloride. CAS No. 1187075-34-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14718A. | |
| Resolvin D1 | Resolvin D1 (RvD1), an endogenous pro-resolving mediator of inflammation, is derived from omega-3 docosahexaenoic acid during the resolution phase of acute inflammation. Resolvin D1 blocks proinflammatory neutrophil migration by regulating actin polymerization, reduces TNF-α - mediated inflammation in macrophages, and enhances phagocytosis of apoptotic cells by macrophages [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: RvD1. CAS No. 872993-05-0. Pack Sizes: 25 μg (265.6 μM * 250 μL in Ethanol). Product ID: HY-125527. | |
| Resolvin D2 | Resolvin D2 is a metabolite of docosahexaenoic acid (DHA), with anti-inflammatory, anti-infective activities. Resolvin D2 is a potent regulator of leukocytes and controls microbial sepsis. Resolvin D2 is a remarkably potent inhibitor of TRPV1 ( IC 50 = 0.1 nM) and TRPA1 ( IC 50 = 2 nM) in primary sensory neurons [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RvD2. CAS No. 810668-37-2. Pack Sizes: 25 μg (265.6 μM * 250 μL in Ethanol); 50 μg (265.6 μM * 500 μL in Ethanol). Product ID: HY-121636. | |
| Resolvin E1 | Resolvin E1 (RvE1), a potent endogenous pro-resolving mediator of inflammation, is derived from omega-3 fatty acid eicosapentaenoic acid (EPA). Resolvin E1 is endogenously biosynthesized from EPA in the presence of Aspirin during the spontaneous resolution phase of acute inflammation, where specific cell-cell interactions occur. Resolvin E1 possesses unique counterregulatory actions that inhibit polymorphonuclear leukocyte (PMN) transendothelial migration. Resolvin E1 also acts as a potent inhibitor of leukocyte infiltration, dendritic cell migration, and IL-12 production [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: RvE1. CAS No. 552830-51-0. Pack Sizes: 10 μg (285.3 μM * 100 μL in Ethanol); 25 μg (285.3 μM * 250 μL in Ethanol). Product ID: HY-114041. | |
| Resolvin E2 | Resolvin E2 ((-)-Resolvin E2), a proresolving lipid mediator, is useful as a lead for anti-inflammatory agent [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (-)-Resolvin E2. CAS No. 865532-70-3. Pack Sizes: 1 μg (149.50 μM * 20 μL in Ethanol); 5 μg (149.50 μM * 100 μL in Ethanol). Product ID: HY-133159. | |
| Resomelagon | Resomelagon (AP1189) is a potent, orally active melanocortin receptor (MR) agonist about MC 1 and MC 3. Resomelagon induces ERK1/2 phosphorylation and Ca 2+ mobilization. Resomelagon has anti-inflammatory activity. Resomelagon can be used for obesity and chronic inflammation research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AP1189. CAS No. 1809420-71-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147301. | |
| Resomelagon acetate | Resomelagon (AP1189) acetate is a potent, orally active melanocortin receptor (MR) agonist about MC 1 and MC 3. Resomelagon acetate induces ERK1/2 phosphorylation and Ca 2+ mobilization. Resomelagon acetate has anti-inflammatory activity. Resomelagon acetate can be used for obesity and chronic inflammation research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AP1189 acetate. CAS No. 1809420-72-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147301A. | |
| Resorufin | Resorufin (NSC 12097) is a highly fluorescent pink dye. Resorufin shows favorable properties such as water solubility, red-shifted absorption/emission signals. Resorufin is used for the detection of ROS/RNS and a second analyte [1] [2]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: NSC 12097. CAS No. 635-78-9. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-123533. | |
| Resorufin acetate | Resorufin acetate is a fluorescent dye that selectively detects hydrazine [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1152-14-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-118262. | |
| Resorufin butyrate | Resorufin butyrate is a fluorogenic substrate for triglyceride lipases and cholinesterase (Ex=570 nm, Em=580 nm) [1] [2] [3]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 15585-42-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-116583. | |
| Resveratrol | Resveratrol (trans-Resveratrol; SRT501), a natural polyphenolic phytoalexin that possesses anti-oxidant, anti-inflammatory, cardioprotective, and anti-cancer properties. Resveratrol (SRT 501) has a wide spectrum of targets including mTOR , JAK , β-amyloid , Adenylyl cyclase , IKKβ , DNA polymerase. Resveratrol also is a specific SIRT1 activator [1] [2] [3] [4]. Resveratrol is a potent pregnane X receptor (PXR) inhibitor [5]. Resveratrol is an Nrf2 activator, ameliorates aging-related progressive renal injury in mice model [6]. Resveratrol increases production of NO in endothelial cells [7]. Uses: Scientific research. Group: Natural products. Alternative Names: trans-Resveratrol; SRT501. CAS No. 501-36-0. Pack Sizes: 10 mM * 1 mL; 200 mg; 500 mg. Product ID: HY-16561. | |
| Resveratroloside | Resveratroloside (Resveratrol glycoside) is an orally active competitive inhibitor of ?-glucosidase. Resveratroloside has hypoglycemic and cardioprotective effects. Resveratroloside can be used for the research of diabetes and heart system diseases[1][2]. Uses: Scientific research. Group: Natural products. Alternative Names: Resveratrol glycoside; trans-Resveratrol 4'-O-?-D-glucopyranoside. CAS No. 38963-95-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N4195. | |
| Retagliptin | Retagliptin (SP2086) is a selective, competitive and orally active dipeptidyl peptidase-4 (DPP-4) inhibitor. Retagliptin can be used for type 2 diabetes mellitus (T2DM) research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SP2086. CAS No. 1174122-54-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-112668A. | |
| Retagliptin phosphate | Retagliptin phosphate (SP2086 phosphate) is a selective, competitive and orally active dipeptidyl peptidase-4 (DPP-4) inhibitor. Retagliptin phosphate can be used for type 2 diabetes mellitus (T2DM) research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SP2086 phosphate. CAS No. 1256756-88-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-112668. | |
| Retapamulin | Retapamulin (SB-275833) is a topical antibiotic that binds Staphylococcus aureus and E. coli ribosomes with a Kd of 3 nM. Retapamulin can be used in researches of atopic dermatitis and prostate cancer [1] [2] [8]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SB-275833. CAS No. 224452-66-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17010. | |
| Retaspimycin Hydrochloride | Retaspimycin Hydrochloride is a potent inhibitor of Hsp90 with EC 50 s of 119 nM for both Hsp90 and Grp9. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IPI-504. CAS No. 857402-63-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10210. | |
| Retatrutide | Retatrutide (LY3437943) is a triple agonist peptide of the glucagon receptor (GCGR), glucosedependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R). Retatrutide binds human GCGR, GIPR, and GLP-1R with EC 50 values of 5.79, 0.0643 and 0.775 nM, respectively. Retatrutide can be used for the research of obesity [1]. Uses: Scientific research. Group: Peptides. Alternative Names: LY3437943. CAS No. 2381089-83-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P3506. | |
| Reticuline | Reticuline shows anti-inflammatory effects through JAK2/STAT3 and NF-κB signaling pathways. Reticuline inhibits mRNA expressions of TNF-α, and IL-6 and reduces the phosphorylation levels of JAK2 and STAT3 [1]. Reticuline exhibits cardiovascular effects [2]. Uses: Scientific research. Group: Natural products. CAS No. 485-19-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N1356. | |
| (±)-Reticuline | (±)-Reticuline (compound 3f) is a natural product obtained from Peumus boldus Molina. (±)-Reticuline can be used to synthesize S-Reticuline [1]. Uses: Scientific research. Group: Natural products. CAS No. 1699-46-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-135489. | |
| Retifanlimab | Retifanlimab is an anti-programmed cell death protein 1 (anti-PD-1) monoclonal antibody (mAb). Retifanlimab can be used for the research of gastroesophageal adenocarcinoma (GEA) [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2079108-44-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99941. | |
| Retinoic acid | Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC 50 s of 14 nM for RARα/β/&gamma. Retinoic acid bind to PPARβ/δ with K d of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha. Uses: Scientific research. Group: Natural products. Alternative Names: Vitamin A acid; all-trans-Retinoic acid; ATRA. CAS No. 302-79-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-14649. | |
| Retinoic acid (GMP) | Retinoic acid (Vitamin A acid) (GMP) is Retinoic acid (HY-14649) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Retinoic acid is an agonist of RAR nuclear receptors[1][2][3][4][5][6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Vitamin A acid (GMP); all-trans-Retinoic acid (GMP); ATRA (GMP). CAS No. 302-79-4. Pack Sizes: 10 mg; 50 mg. Product ID: HY-14649G. | |
| Retinoic acid (Standard) | Retinoic acid (Standard) is the analytical standard of Retinoic acid. This product is intended for research and analytical applications. Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RAR?/?/?. Retinoic acid bind to PPAR?/? with Kd of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha. Uses: Scientific research. Group: Natural products. Alternative Names: Vitamin A acid (Standard); all-trans-Retinoic acid (Standard); ATRA (Standard). CAS No. 302-79-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-14649R. | |
| Retinyl acetate | Retinyl acetate is a synthetic acetate ester form derived from retinol and has potential antineoplastic and chemo preventive activities [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Retinol acetate; Vitamin A acetate. CAS No. 127-47-9. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg. Product ID: HY-N0679. | |
| Retinyl palmitate | Retinyl palmitate is an ester of Retinol and is the major form of vitamin A found in the epidermis. Retinyl palmitate has been widely used in pharmaceutical and cosmetic formulations. Uses: Scientific research. Group: Natural products. Alternative Names: Vitamin A palmitate; Retinol palmitate. CAS No. 79-81-2. Pack Sizes: 100 mg. Product ID: HY-B1384. | |
| Retosiban | Retosiban (GSK221149A) is a potent and selective oxytocin antagonist with a K i of 0.65 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GSK 221149; GSK 221149A. CAS No. 820957-38-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14778. | |
| RETRA | RETRA is a mutant p53-dependent activator of p73 that suppresses mutant p53-bearing cancer cells. RETRA increases the expression level of p73, and a release of p73 from the blocking complex with mutant p53, which produces tumor-suppressor effects [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1036069-26-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-108636. | |
| Retro-2 | Retro-2 is a selective inhibitor of retrograde protein trafficking at the endosome-trans-Golgi network interface. Retro-2 is an ebolavirus (EBOV) infection inhibitor with an EC 50 of 12.2 μM in HeLa cells. Retro-2 induces cell autophagy [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1201652-50-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122571. | |
| Reutericyclin | Reutericyclin (Reutericycline), a unique tetramic acid, is an antibiotic produced by some strains of Lactobacillus reuteri. Reutericyclin (Reutericycline) exhibits a broad inhibitory spectrum including Lactobacillus spp. , Bacillus subtilis , B. cereus , Enterococcus faecalis , Staphylococcus aureus , and Listeria innocua [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Reutericycline. CAS No. 303957-69-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103249. | |
| Reuterin | Reuterin is a broad-spectrum antimicrobial agent active against Gram positive and Gram negative bacteria, as well as yeasts, moulds and protozoa. Reuterin is produced by specific strains of Lactobacillus reuteri during anaerobic metabolism of glycerol. Reuterin also demonstrates potent antimicrobial activity against a broad panel of human and poultry meat campylobacter spp. Isolates[1][2]. Uses: Scientific research. Group: Natural products. Alternative Names: 3-Hydroxypropionaldehyde; 3-Hydroxypropanal. CAS No. 2134-29-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N8461. | |
| Revaprazan hydrochloride | Revaprazan hydrochloride is a novel acid pump antagonist ( APA ). Revaprazan hydrochloride reduces COX-2 expression and has significant anti-inflammatory actions activities in H. pylori infection [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 178307-42-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N7067. | |
| Revefenacin | Revefenacin (TD-4208; GSK1160724) is a potent mAChR antagonist; has a high affinity on M3 receptor with a K i of 0.18 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TD-4208; GSK1160724. CAS No. 864750-70-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15851. | |
| Reveromycin A | Reveromycin A, a benzoquinoid antibiotic isolated from the genus Streptomyces , is a selective inhibitor of protein synthesis in eukaryotic cells. Reveromycin A inhibits bone resorption by inducing apoptosis specifically in osteoclasts. Reveromycin A has antiproliferative activity against tumor cell lines and antifungal activity [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 134615-37-5. Pack Sizes: 1 mg. Product ID: HY-129337. | |
| Reversan | Reversan (CBLC4H10) is a potent and nontoxic multidrug resistance-associated protein 1 (MRP1) and P-glycoprotein (Pgp) inhibitor[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CBLC4H10. CAS No. 313397-13-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107643. | |
| Reverse T3 | Reverse T3 is a thyroid hormone that can be generated by deiodination of the prohormone thyroxine [1]. Reverse T3 inhibits the increase of sodium current generated by other thyroid hormone analogs in neonatal rat myocytes [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 3,5,3-Triiodothyronine. CAS No. 5817-39-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-W010696. | |
| Reverse transcriptase-IN-1 | Reverse transcriptase-IN-1 (Compound 12z), a diarylbenzopyrimidine (DABP) analogue, is a potent, orally active HIV-1 nonnucleoside reverse transcriptase inhibitor. Reverse transcriptase-IN-1 has antiviral activity with EC 50 values of 3.4 nM, 4.3 nM and 3.6 nM for HIV-1 III B , E138K and K103N mutants, respectively. Reverse transcriptase-IN-1 also has an IC 50 of 13.7 nM against HIV-1 reverse transcriptase enzyme [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2380001-43-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130241. | |
| Reversine | Reversine is a novel class of ATP-competitive Aurora kinase inhibitor with IC 50 s of 400, 500 and 400 nM for Aurora A , Aurora B and Aurora C , respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 656820-32-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14711. | |
| Revumenib | Revumenib (SNDX-5613) is a potent and specific Menin-MLL inhibitor with a binding K i of 0.149 nM and a cell based IC 50 of 10-20 nM. Revumenib can be used for the research of MLL-rearranged (MLL-r) acute leukemias, including acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SNDX-5613. CAS No. 2169919-21-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136175. | |
| Rezafungin acetate | Rezafungin acetate (Biafungin acetate) is a next-generation, broad-spectrum, and long-lasting echinocandin. Rezafungin acetate shows potent antifungal activity against Candida spp. , Aspergillus spp. , and Pneumocystis spp. [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Biafungin acetate; CD101 acetate; SP-3025 acetate. CAS No. 1631754-41-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108009A. | |
| Rezatapopt | Rezatapopt (PC14586) is an orally active antineoplastic agent. Rezatapopt binds to a pocket created by the TP53 Y220C mutation. Rezatapopt restores p53 tumor suppressor functions by stabilization of the p53 protein structure. Rezatapopt demonstrates tumor inhibition and regression in mouse models with established human tumor xenografts harboring the TP53 Y220C mutation [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PC14586. CAS No. 2636846-41-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156633. | |
| Rezorstobart | Rezorstobart is an anti- KLRB1 human IgG1 κ monoclonal antibody [1]. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001). Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2762201-86-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990760. | |
| Rezvilutamide | Rezvilutamide (SHR3680) is an orally active androgen receptor antagonist. Rezvilutamide (SHR3680) is used for the study of prostate cancer [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SHR3680. CAS No. 1572045-62-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-137448. | |
| RF9 | RF9 is a potent and selective Neuropeptide FF receptor antagonist, with K i values of 58 and 75 nM for hNPFF1R and hNPFF2R , respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 876310-60-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-107382. | |
| RFRP-1(human) | RFRP-1(human) is a gonadotropin-inhibitory hormone (GnIH) homolog. RFRP-1(human) targets human gonadotropin-releasing hormone (GnRH) neurons and gonadotropes and potently inhibits gonadotropin. RFRP-1(human) is a potent Neuropeptide FF (NPFF) receptor agonist with EC50s of 0.0011 nM and 29 nM for NPFF2 and NPFF1 , respectively [1] [2] [3]. Uses: Scientific research. Group: Peptides. CAS No. 311309-25-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1428. | |
| RFRP-3(human) | RFRP-3 (Neuropeptide VF(124-131))(human), a human GnIH peptide homolog, is a potent inhibitor of gonadotropin secretion by inhibiting Ca 2+ mobilization. RFRP-3(human) is a NPFF1 receptor agonist, it inhibits forskolin-induced production of cAMP with an IC 50 of 0.7 nM [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Neuropeptide VF(124-131)(human); Neuropeptide NPVF (human). CAS No. 311309-27-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1250. | |
| RG100204 | RG100204 is a selective, orally available inhibitor of the aquaporin AQP9. RG100204 directly inhibits AQP9 channel function, preventing the transmembrane transport of water, glycerol, and H2O2. RG100204 reduces the activation of the NLRP3 inflammasome and p38 MAPK signaling pathways, thereby alleviating inflammation and pyroptosis. RG100204 reduces multi-organ dysfunction in a mouse sepsis model and shows glucose-regulating effects in diabetic db/db mice[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2140901-88-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-161834. | |
| RG108 | RG108 (N-Phthalyl-L-tryptophan) is a non-nucleoside DNA methyltransferases (DNMTs) inhibitor (IC50=115 nM) that blocks the DNMTs active site. RG108 (N-Phthalyl-L-tryptophan) causes demethylation and reactivation of tumor suppressor genes, but it does not affect the methylation of centromeric satellite sequences[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: N-Phthalyl-L-tryptophan. CAS No. 48208-26-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-13642. | |
| RG2833 | RG2833 is a brain-penetrant HDAC inhibitor with IC50s of 60 nM and 50 nM for HDAC1 and HDAC3, respectively. The Ki values for HDAC1 and HDAC3 are 32 and 5 nM, respectively[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RGFP109. CAS No. 1215493-56-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-16425. | |
| RG7112 | RG7112 is a potent, selective, first clinical, orally active and blood-brain barrier crossed MDM2-p53 inhibitor, with an IC50 of 18 nM and a KD of 11 nM for binding to MDM2[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RO5045337. CAS No. 939981-39-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10959. | |
| RG7800 | RG7800 is a SMN2 splicing modifier. RG7800 has the potential for spinal muscular atrophy treatment. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RO6885247. CAS No. 1449598-06-4. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-101792. | |
| RG7800 tetrahydrochloride | RG7800 hydrochloride is an orally active SMN2 splicing modulator, with EC1.5xs of 23 nM and 87 nM for SMN2 splicing and SMN protein; RG7800 hydrochloride has the potential to treat spinal muscular atrophy. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RO6885247 tetrahydrochloride. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-101792A. | |
| RG7834 | RG7834 (RO 7020322) is a highly selective and orally bioavailable HBV inhibitor, potently inhibits HBV antigens (both HBsAg and HBeAg) and HBV DNA, with IC50s of 2.8, 2.6, and 3.2 nM, respectively, in dHepaRG Cells[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RO 7020322. CAS No. 2072057-17-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-117650A. | |
| RGB-1 | RGB-1 is a polycyclic aromatic hydrocarbon molecule and a stabilizer of RNA G-quadruplexes. RGB-1 can promote the inhibition of RNA translation and reduce the expression of NRAS proto-oncogene in breast cancer cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 930455-91-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-156228. | |
| RGB-286638 | RGB-286638 is a CDK inhibitor that inhibits the kinase activity of cyclin T1-CDK9, cyclin B1-CDK1, cyclin E-CDK2, cyclin D1-CDK4, cyclin E-CDK3, and p35-CDK5 with IC50s of 1, 2, 3, 4, 5 and 5 nM, respectively; also inhibits GSK-3?, TAK1, Jak2 and MEK1, with IC50s of 3, 5, 50, and 54 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 784210-87-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15504. | |
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