MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
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Xanthorrhizol
Xanthorrhizol, isolated from Curcuma xanthorrhiza Roxb, is a potential antibacterial agent. Uses: Scientific research. Group: Natural products. CAS No. 30199-26-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 1 mg. Product ID: HY-112657.
Xanthosine
Xanthosine is a nucleoside derived from xanthine and ribose. Xanthosine can increase mammary stem cell population and milk production in cattle and goats [1]. Uses: Scientific research. Group: Natural products. CAS No. 146-80-5. Pack Sizes: 10 mM * 1 mL; 50 mg. Product ID: HY-W011527.
Xanthurenic acid
Xanthurenic acid is a putative endogenous Group II metabotropic glutamate receptor agonist, on sensory transmission in the thalamus. Uses: Scientific research. Group: Natural products. CAS No. 59-00-7. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-W014666.
Xantphos
Xantphos (9,9-Dimethyl-4,5-bis(diphenylphosphino)xanthene) is a biochemical reagent that can be used as a biological material or organic compound for life science related research [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: 9,9-Dimethyl-4,5-bis(diphenylphosphino)xanthene. CAS No. 161265-03-8. Pack Sizes: 25 g. Product ID: HY-Y0091.
XAP044
XAP044 is a potent and selective antagonist of mGlu7. The metabotropic glutamate receptor subtype 7 (mGlu7) is an important presynaptic regulator of neurotransmission in the mammalian CNS. XAP044 demonstrates good brain exposure and wide spectrum anti-stress and antidepressant- and anxiolytic-like efficacy in rodent behavioral paradigms [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 196928-50-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-110146.
XAV-939
XAV-939 is a Tankyrase inhibitor. XAV-939 has inhibitory activity for TNKS1 and TNKS2 with IC 50 values of 5 nM and 2 nM, respectively. XAV-939 also is an enhancer of osteoblastic differentiation of hMSCs. XAV-939 can be used for the research of conditions associated with activated Wnt signaling, such as cancer, fibrotic diseases and conditions associated with low bone formation [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 284028-89-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-15147.
XCT790
XCT-790 is a potent and selective inverse agonist for ERRα with an IC 50 value of 0.37 μM. XCT-790 induces cell death in chemotherapeutic resistant cancer cells. XCT-790 (Compound 12) is inactive against ERRγ and the estrogen receptors ERα and ERβ [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 725247-18-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-10426.
XE991 dihydrochloride
XE991 dihydrochloride, a Kv7 (KCNQ) channels blocker, potently inhibits Kv7.1 (KCNQ1) , Kv7.2 (KCNQ2) , Kv7.2 + Kv7.3 (KCNQ3) channel, and M-current with IC 50 s of 0.75 μM, 0.71 μM, 0.6 μM, and 0.98 μM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 122955-13-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108577.
Xeligekimab
Xeligekimab (GR 1501) is an anti- human interleukin 17A (IL-17A) humanized monoclonal antibody. Xeligekimab inhibits the pro-inflammatory cascade [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: GR 1501. CAS No. 2382921-73-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99515.
Xenin
Xenin is a 25-amino acid peptide initially isolated from human gastric mucosa. Xenin is a gut hormone that can reduce food intake. Uses: Scientific research. Group: Peptides. CAS No. 144092-28-4. Pack Sizes: 500 μg; 5 mg; 10 mg. Product ID: HY-P0259.
Xentuzumab
Xentuzumab (Anti-Human IGF1 and IGF2 Recombinant Antibody; BI836845) is a recombinant a human monoclonal antibody that targets IGF ligands IGF1 and IGF2. Xentuzumab inhibits both of IGF1 and IGF2 growth-promoting signalling and suppresses AKT activation [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BI 836845; Anti-Human IGF1 and IGF2 Recombinant Antibody. CAS No. 1417158-65-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99274.
Xevinapant
Xevinapant (AT-406) is a potent and orally bioavailable Smac mimetic and an antagonist of IAPs , and it binds to XIAP, cIAP1, and cIAP2 proteins with K i of 66.4, 1.9, and 5.1 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AT-406; Debio 1143; SM-406. CAS No. 1071992-99-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15454.
Xevinapant hydrochloride
Xevinapant (AT-406) hydrochloride is a potent and orally bioavailable Smac mimetic and an antagonist of the inhibitor of apoptosis proteins (IAPs). Xevinapant hydrochloride binds to XIAP, cIAP1, and cIAP2 proteins with K i s of 66.4, 1.9, and 5.1 nM, respectively. Xevinapant hydrochloride effectively antagonizes XIAP BIR3 protein in a cell-free functional assay, induces rapid degradation of cellular cIAP1 protein, and inhibits cancer cell growth in various human cancer cell lines. Xevinapant hydrochloride is highly effective in induction of apoptosis in xenograft tumors [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AT-406 hydrochloride; Debio 1143 hydrochloride; SM-406 hydrochloride. CAS No. 1071992-57-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-13208.
X-GAL
X-GAL (BCIG) is a widely used chromogenic β-galactosidase substrate. X-GAL is a colorless compound until cleaved by β-galactosidase, at which point X-GAL turns to an insoluble and detectable blue compound, making X-GAL particularly useful in techniques such as blue-white screening for cloning in bacteria. X-GAL can also be used for detection of β-galactosidase activity [1] [2]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: BCIG. CAS No. 7240-90-6. Pack Sizes: 200 mg; 500 mg; 1 g; 2 g. Product ID: HY-15934.
X-Gluc cyclohexanamine
X-Gluc cyclohexanamine is a dye reagent for the detection of β-glucuronidase ( GUS ), an enzyme produced by E. coli. X-Gluc cyclohexanamine can be used to detect E. coli contamination in food, water and the urinary tract ( GUS as a specific detection indicator). X-Gluc cyclohexanamine is also widely used in molecular biology experiments to label and detect the expression of target genes (reacts with the GUS gene , appears blue) [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 114162-64-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15935B.
X-Gluc Dicyclohexylamine
X-Gluc Dicyclohexylamine is a dye reagent for the detection of β-glucuronidase, an enzyme produced by Escherichia coli. X-Gluc sodium can be used to detect E. coli contamination in food, water and the urinary tract. X-Gluc sodium is also widely used in molecular biology experiments to label and detect the expression of target genes (GUS reporter system) [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 18656-96-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-15935.
X-Gluc sodium
X-Gluc sodium is a dye reagent for the detection of β-glucuronidase ( GUS ), an enzyme produced by E. coli. X-Gluc sodium can be used to detect E. coli contamination in food, water and the urinary tract ( GUS as a specific detection indicator). X-Gluc sodium is also widely used in molecular biology experiments to label and detect the expression of target genes (reacts with the GUS gene , appears blue) [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 129541-41-9. Pack Sizes: 50 mg; 100 mg. Product ID: HY-15935C.
Ximelagatran
Ximelagatran (H 376/95) is an orally active thrombin inhibitor that selectively and competitively inhibits both free and clot-bound thrombin. Ximelagatran is an anticoagulant agent with a rapid onset of anticoagulant effect, predictable, dose-dependent pharmcokinetics and pharmacodynamics [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: H 376/95. CAS No. 192939-46-1. Pack Sizes: 10 mM * 1 mL; 500 μg; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10787.
Xipamide
Xipamide is a sulfonamide-based diuretic. Xipamide is an antihypertensive agent able to selectively inhibit the anion exchanger (AE) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 14293-44-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-W042301.
XL44
XL44, an hRpn13 binder, induces hRpn13-dependent apoptosis and also restricts cell viability by a PCLAF-dependent mechanism. XL44 induces ubiquitin-dependent loss of hRpn13 Pru and ubiquitin-independent loss of select KEN box containing proteins [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2637949-91-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-162393.
XL 999
XL999 is a multi-target tyrosine kinase inhibitor. XL999 has IC 50 values for KDR , Flt-1 , FGFR1 and PDGFRα of 4 nM, 20 nM, 4 nM and 2 nM, respectively. XL999 can be used in the research of cancer [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Tyrosine kinase-IN-1. CAS No. 705946-27-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100315.
XMD-17-51 TFA
XMD-17-51 TFA is a pyrimido-diazepinone compound that is able to modulate protein kinases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2436579-93-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-117291A.
XMD8-92
XMD8-92 is a potent ERK5 (BMK1)/BRD4 inhibitor with K d s of 80 and 190 nM, respectively. XMD8-92 inhibits DCAMKL2, PLK4 and TNK1 with K d s of 190, 600 and 890 nM, respectively. Anti-cancer activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1234480-50-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14443.
XMU-MP-2
XMU-MP-2 is a BRK inhibitor with significant inhibitory activity on BRK-positive cells. XMU-MP-2 inhibits oncogenic BRK-driven tumor growth in a mouse xenograft model. XMU-MP-2 also synergizes with HER2 inhibitors or endoplasmic reticulum (ER) blockade to exert antiproliferative activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2031152-10-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-122664.
XO44
XO44 (PF-6808472) is a broad-spectrum covalent kinase probe. XO44 can bind in CDK 2 and CDK 1. XO44 also labels CDK4 proteins in cells [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PF-6808472. CAS No. 2088112-70-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122609.
XP-59
XP-59 is a potent inhibitor of the SARS-CoV M pro , with a K i of 0.1 μM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 890402-73-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-136284.
XPhos
XPhos (2-(Dicyclohexylphosphino)-2',4',6'-triisopropylbiphenyl) is a biochemical reagent that can be used as a biological material or organic compound for life science related research [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: 2-(Dicyclohexylphosphino)-2',4',6'-triisopropylbiphenyl. CAS No. 564483-18-7. Pack Sizes: 10 g; 25 g. Product ID: HY-Y0006.
XR5944
XR5944 is an anti-tumor compound with DNA-targeting activity. As a topoisomerase inhibitor, XR5944 can effectively inhibit the activities of topoisomerase I and II. XR5944 shows excellent anti-tumor activity against human and mouse tumor cells in vitro and in vivo. XR5944 exhibits significant potency in multiple cell lines, with IC 50 values of 0.04-0.4 nM. XR5944 is not affected by atypical drug resistance in cells and remains significantly active even in cells overexpressing P-glycoprotein or multidrug resistance-related proteins. XR5944 showed anti-tumor efficacy in human tumor models of H69 small cell lung cancer and HT29 colon cancer, inducing tumor regression in most animals in the HT29 model. XR5944 can be used to study biological processes related to colon and lung cancer [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 343247-32-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-118899.
XT2
XT2 is a potent, orally active, and selective inhibitor of NF-κB-inducing kinase ( NIK ) with an IC 50 of 9.1 nM. XT2 suppresses CCl4-induced upregulation of ALT, a key biomarker of acute liver injury. XT2 also decreases immune cell infiltration into the injured liver tissue. XT2 has the potential for the research of liver inflammatory diseases [1]. XT2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 2582816-37-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145801.
XTT sodium
XTT (sodium) is used to assess cell viability as a function of redox potential. Actively respiring cells convert the water-soluble XTT to a water-soluble, orange colored formazan product. Uses: Scientific research. Group: Signaling pathways. CAS No. 111072-31-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122131.
XY101
XY101 is a potent, selective, metabolically stable and orally available RORγ inverse agonist with an IC 50 of 30 nM and a K d of 380 nM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2349368-16-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128604.
Xylan
Xylan represents the main hemicellulose component in the secondary plant cell walls of flowering plants. Xylan is a polysaccharide made from units of xylose and contains predominantly β-D-xylose units linked as in cellulose [1]. Uses: Scientific research. Group: Natural products. CAS No. 9014-63-5. Pack Sizes: 500 mg; 1 g; 5 g. Product ID: HY-107846.
Xylene Cyanol FF
Xylene Cyanol FF is an acid triphenylmethane dye. Xylene Cyanol FF can be used for histochemical staining of hemoglobin peroxidase or as a tracking dye for DNA sequencing in electrophoresis. Xylene Cyanol FF will be catalyzed by Fe and Al to accelerate oxidation under the addition of double oxidant hydrogen peroxide and potassium periodate. Xylene Cyanol FF thus enables the spectrophotometric determination of Fe and Al in the solution to be tested [1] [2]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 2650-17-1. Pack Sizes: 1 g; 5 g; 10 g. Product ID: HY-D0945.
Xylitol
Xylitol can be classified as a polyol and sugar alcohol, exhibiting inhibitory activity on cancer cell proliferation. It induces autophagy ( Autophagy ) and cell death in A549 cells by activating the autophagy signaling pathway, as evidenced by the increased expression of LC3-II and Atg5-Atg12 upon Xylitol treatment. Additionally, Xylitol inhibits acetaldehyde production by Candida species, thereby reducing their carcinogenic potential. In vivo, Xylitol induces alterations in the gut microbiota of mice, which may enhance cholesterol accumulation and upregulate hepatic ChREBP, while also slowing tumor growth in the B16F10 melanoma C57BL/6 mouse model [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Xylite. CAS No. 87-99-0. Pack Sizes: 10 mM * 1 mL; 1 g. Product ID: HY-N0538.
Xylobiose
Xylobiose (1,4-β-D-Xylobiose; 1,4-D-Xylobiose) is a disaccharide of xylose monomers with a β-1, 4 bond between monomers [1]. Uses: Scientific research. Group: Natural products. Alternative Names: 1,4-β-D-Xylobiose; 1,4-D-Xylobiose. CAS No. 6860-47-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N2468.
Xylometazoline hydrochloride
Xylometazoline hydrochloride is an α-adrenergic receptor agonist ( K i =0.05-1.7 μM). Xylometazoline hydrochloride can constrict nasal blood vessels and increase nasal airflow. Xylometazoline hydrochloride can be used in nose stuffiness and runny nose research [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1218-35-5. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-B0475.
Xylose
Xylose (D-(+)-Xylose) is a natural pentose sugar that is catalyzed by xylose isomerase to form xylulose, which is a key step in the anaerobic ethanol fermentation of Xylose. Xylose can be used by microorganisms to produce fuels, chemicals, and bulk industrial enzymes. Xylose provides the substances and energy for cells, as a carbon source for the biosynthesis of high-value chemicals and biofuel. Xylose can be used to fully explore lignocellulose resources and provide a new direction for microbia fermentation [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: D-(+)-Xylose; (+)-Xylose; Wood sugar. CAS No. 58-86-6. Pack Sizes: 10 mM * 1 mL; 50 g; 100 g. Product ID: HY-N0537.
Xylotriose
Xylotriose is a natural xylooligosaccharide, acts as a bifidogenic factor [1]. Uses: Scientific research. Group: Natural products. CAS No. 47592-59-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 20 mg. Product ID: HY-N2469.
Y11
Y11 inhibits FAK1 autophosphorylation by blocking phosphorylation of Y397 and decreases tumor growth [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1086639-59-9. Pack Sizes: 1 mg. Product ID: HY-103471.
Y16
Y16 is a specific inhibitor of Leukemia-associated Rho guanine nucleotide exchange factor (LARG) with a K d value of 76 nM. Y16 is active in blocking the interaction of LARG and related G-protein-coupled Rho GEFs with RhoA. Y16 shows no detectable effect on other diffuse B-cell lymphoma (Dbl) family Rho GEFs, Rho effectors, or a RhoGAP [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 429653-73-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-12649.
Y1 receptor antagonist 1
Y1 receptor antagonist 1 (H 409-22 isomer) is a neuropeptide Y1 receptor antagonist. Uses: Scientific research. Group: Signaling pathways. Alternative Names: H 409-22 (isomer). CAS No. 221697-09-2. Pack Sizes: 1 mg. Product ID: HY-101704.
Y-27632
Y-27632 is an orally active, ATP-competitive inhibitor of ROCK-I and ROCK-II , with K i s of 220 and 300 nM, respectively. Y-27632 attenuates Doxorubicin-induced apoptosis of human cardiac stem cells. Y-27632 also suppresses dissociation-induced apoptosis of murine prostate stem/progenitor cells. Y-27632 primes human induced pluripotent stem cells (hIPSCs) to selectively differentiate towards mesendodermal lineage via epithelial-mesenchymal transition-like modulation [1] [2] [3] [4] [5] [6] [7]. Uses: Scientific research. Group: Signaling pathways. CAS No. 146986-50-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-10071.
Y-27632 dihydrochloride
Y-27632 dihydrochloride is an orally active and ATP-competitive ROCK ( Rho-kinase ) inhibitor (ROCK-I K i =220 nM; ROCK-II K i =300 nM). Y-27632 dihydrochloride shows antiepileptic effects [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 129830-38-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10583.
Y-27632 (dihydrochloride) (Standard)
Y-27632 (dihydrochloride) (Standard) is the analytical standard of Y-27632 (dihydrochloride). Y-27632 dihydrochloride is an orally active and ATP-competitive ROCK ( Rho-kinase ) inhibitor (ROCK-I K i =220 nM; ROCK-II K i =300 nM). Y-27632 dihydrochloride shows antiepileptic effects [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 129830-38-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10583R.
Yamogenin
Yamogenin (Neodiosgenin) is a diastereomer of diosgenin. Yamogenin (Neodiosgenin) antagonizes the activation of the liver X receptor (LXR) in luciferase ligand assay. Yamogenin (Neodiosgenin) inhibits triacylglyceride (TG) accumulation through the suppression of gene expression of fatty acid synthesis in HepG2 hepatocytes [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Neodiosgenin. CAS No. 512-06-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N2078.
Yangonin
Yangonin exhibits affinity for the human recombinant cannabinoid CB1 receptor with an IC 50 and a K i of 1.79 μM and 0.72 μM, respectively. Uses: Scientific research. Group: Natural products. CAS No. 500-62-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N0919.
YCT529
YCT529 is a potent, selective and orally active RAR-α inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2863670-67-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153122A.
Yeast extract
Yeast extract is a concentrate of the soluble part of yeast, especially Saccharomyces cerevisiae. The main nutritional components of yeast extract include partly hydrolyzed protein with 35-40% of free amino acid, and it also contain B vitamins and some trace elements. Yeast extract can be used as nutrients for bacterial culture media [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 8013-1-2. Pack Sizes: 50 g; 100 g. Product ID: HY-153126.
YF-2
YF-2 is a highly selective, blood-brain-barrier permeable histone acetyltransferase activator, acetylates H3 in the hippocampus, with EC 50 s of 2.75 μM, 29.04 μM and 49.31 μM for CBP, PCAF, and GCN5, respectively, shows no effect on HDAC. Anti-cancer and anti-Alzheimer's disease [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1311423-89-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16531.
YF-2 hydrochloride
YF-2 hydrochloride is a highly selective, blood-brain-barrier permeable histone acetyltransferase activator, acetylates H3 in the hippocampus, with EC 50 s of 2.75 μM, 29.04 μM and 49.31 μM for CBP, PCAF, and GCN5, respectively, shows no effect on HDAC. Anti-cancer and anti-Alzheimer's disease [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1312005-62-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-16531A.
YIGSR
YIGSR is a peptide that can inhibit the tumour growth and metastasis of leukaemic cells [1]. YIGSR blocks the cellular binding to laminin I via a 67-kDa laminin-binding protein, and inhibits shear-induced increase in eNOS expression of laminin cells [2]. Uses: Scientific research. Group: Peptides. Alternative Names: Laminin Fragment 929-933. CAS No. 110590-64-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0132.
YIL781
YIL781 is a potent and orally active ghrelin receptor (GHSR) antagonist. YIL781 produces a greater improvement in glucose homeostasis in rats. YIL781 inhibits the calcium response induced by ghrelin with pIC 50 values of 7.90 and 8.27, respectively [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 875258-85-8. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-13964.
YIL781 hydrochloride
YIL781 hydrochloride is a potent and orally active ghrelin receptor (GHSR) antagonist. YIL781 hydrochloride produces a greater improvement in glucose homeostasis in rats. YIL781 hydrochloride inhibits the calcium response induced by ghrelin with pIC 50 values of 7.90 and 8.27, respectively [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1640226-17-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-13964A.
YK11
YK11 is a partial agonist of androgen receptor , with osteogenic activity. Uses: Scientific research. Group: Signaling pathways. CAS No. 1370003-76-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-107480.
YK-2168
YK-2168 is a differentiated selective inhibitor of CDK9 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2571068-74-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-162919.
YK-4-279
YK-4-279 blocks RNA Helicase A (RHA) binding with EWS-FLI1 (oncogenic protein). YK-4-279 induces apoptosis and shows anti-proliferation activities towards various cancer cells. YK-4-279 has a chiral center and it can be separated into two enantiomers. YK-4-279 can be used for the research of cancer [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1037184-44-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14507.
YM-298198 hydrochloride
YM-298198 hydrochloride is a high-affinity, selective, orally active, and non-competitive antagonist of metabotropic glutamate receptor type 1 (mGluR1). YM-298198 hydrochloride can be used for the research of neurological disorders [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1216398-09-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-103568.
Yoda 1
Yoda 1 is a potent and selective Piezo1 agonist. Yoda 1 activates purified Piezo1 channels. Yoda 1 potently inhibits macropinocytosis induced by epidermal growth factor (EGF). Yoda 1 enhances Ca 2+ influx followed by activation of the calcium-activated potassium channel KCa3.1 and inhibition of Rac1 activation [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 448947-81-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18723.
Yohimbine Hydrochloride
Yohimbine hydrochloride is an alpha-2 renal adenomatase receptor inhibitor, blocking pre- and post-contact alpha-2 renal adenomatase receptors, causing the release of renal adenoma and multiple sclerosis. Uses: Scientific research. Group: Natural products. CAS No. 65-19-0. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-N0127.
YQA14
YQA14 is a high affinity dopamine D3 receptor antagonist. YQA14 is anti-opioid addiction agent. YQA14 inhibits Morphine/Cocaine-induced conditioned place preference (CPP) in animals [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1221408-42-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-116181.
YS 035 hydrochloride
YS 035 hydrochloride is a Ca 2+ antagonist on cellular uptake and mitochondrial efflux of calcium ions. YS 035 hydrochloride inhibits Ca 2+ uptake by muscle cells and inhibits Na + /Ca 2+ exchange ( K i =28 μM). YS 035 hydrochloride is a useful tool for research on the mitochondrial Ca 2+ transport [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 89805-39-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-100928.
(Z)-3-Butylidenephthalide
(Z)-3-Butylidenephthalide is an antihyperglycemic agent by inhibiting the activity of intestinal and yeast R-glucosidases (IC 50 =2.35 mM; K i =4.86 mM) [1]. Uses: Scientific research. Group: Natural products. Alternative Names: (Z)-Butylidenephthalide. CAS No. 72917-31-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N0336A.
(Z)-9-Tricosene
(Z)-9-Tricosene (cis-9-Tricosene) is an insect pheromone present in flies of the order Diptera (such as the housefly) and can be used as an insecticide [1]. Uses: Scientific research. Group: Natural products. Alternative Names: cis-9-Tricosene. CAS No. 27519-02-4. Pack Sizes: 100 mg; 500 mg. Product ID: HY-W009165.
Zabadinostat
Zabadinostat (CXD101) is a potent, selective and orally active class I HDAC inhibitor with IC 50 s of 63 nM, 570 nM and 550 nM for HDAC1 , HDAC2 and HDAC3 , respectively. Zabadinostat has no activity against HDAC class II. Zabadinostat has antitumor activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CXD101. CAS No. 934828-12-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100748.
Zabofloxacin hydrochloride
Zabofloxacin hydrochloride (DW-224a) is a potent and seletive inhibitor of the bacterial type II and IV topoisomerases. Zabofloxacin hydrochloride has excellent activity against gram-positive pathogens including Steptococcus aureus , Streptococcus pyogenes and S.pneumonia. Zabofloxacin hydrochloride is a novel fluoronaphthyridone quinolone that is considered as an alternative antibiotic for treatment of quinolone-susceptible (QSSP) and quinolone-resistant gonorrhea (QRSP) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DW-224a. CAS No. 623574-00-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106410A.
Zacopride hydrochloride
Zacopride hydrochloride is an orally active 5-HT 3 receptor ( K i of 0.38 nM) antagonist and 5-HT 4 receptor ( K i of 373 nM) agonist. Zacopride hydrochloride exhibits multiple activities, such as regulating gastrointestinal motility, affecting cardiac function, and exerting anxiolytic and antiemetic effects. Zacopride hydrochloride is currently mainly used in the research of gastrointestinal diseases, cardiovascular diseases, and psychiatric diseases such as anxiety [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [11]. Uses: Scientific research. Group: Signaling pathways. CAS No. 101303-98-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103137.
Z-AEVD-FMK
Z-AEVD-FMK is a cleavable ADC linker for the synthesis of antibody active molecule conjugates (ADCs). Uses: Scientific research. Group: Signaling pathways. CAS No. 1135688-47-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125305.
Zafirlukast
Zafirlukast (ICI 204219) is a potent orally active leukotriene D 4 ( LTD 4 ) receptor antagonist. Zafirlukast shows anti-asthmatic, anti-inflammatory and anti-bacterial effects. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ICI 204219. CAS No. 107753-78-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-17492.
Zagotenemab
Zagotenemab (LY3303560) is a humanised anti- tau antibody that selectively binds and neutralises tau deposits in the brain. Zagotenemab can be used in Alzheimer's disease research [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: LY33003560. CAS No. 2019133-28-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99164.
Z-Ala-Ala-OH
Z-Ala-Ala-OH is a non-polar amino acid that can be used in enzymatic peptide synthesis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 16012-70-7. Pack Sizes: 1 g; 5 g. Product ID: HY-133803.