MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Quisinostat dihydrochloride | Quisinostat dihydrochloride (JNJ-26481585 dihydrochloride) is an orally available, potent pan- HDAC inhibitor with IC 50 s of 0.11 nM, 0.33 nM, 0.64 nM, 0.46 nM, and 0.37 nM for HDAC1, HDAC2, HDAC4, HDAC10 and HDAC11, respectively. Quisinostat dihydrochloride has a broad spectrum antitumoral activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: JNJ-26481585 dihydrochloride. CAS No. 875320-31-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-15433A. |  |
| Quisovalimab | Quisovalimab (AVTX-002; AEVI 002; SAR 252067) is a human monoclonal antibody against LIGHT , a tumor necrosis factor (TNF)-related cytokine (TNFSF14) that plays an important role in acute respiratory distress syndrome (ARDS) and cytokine release syndrome (CRS) COVID-19. Quisovalimab can be used in COVID-19 acute respiratory distress syndrome and other studies [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: AVTX-002; AEVI 002; SAR 252067. CAS No. 2427667-03-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99810. | |
| Quisqualic acid | Quisqualic acid (L-Quisqualic acid), a natural analog of glutamate, is a potent and pan two subsets ( iGluR and mGluR ) of excitatory amino acid (EAA) agonist with an EC 50 of 45 nM and a K i of 10 nM for mGluR1R. Quisqualic acid is isolated from the fruits of Quisqualis indica [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: L-Quisqualic acid. CAS No. 52809-07-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg. Product ID: HY-12597. | |
| Quizartinib | Quizartinib (AC220) is an orally active, highly selective and potent second-generation type II FLT3 tyrosine kinase inhibitor, with a K d of 1.6 nM. Quizartinib inhibits wild-type FLT3 and FLT3-ITD autophosphorylation in MV4-11 cells with IC 50 s of 4.2 and 1.1 nM, respectively. Quizartinib can be linked to the VHL ligand via an optimized linker to form a PROTAC FLT3 degrader. Quizartinib induces apoptosis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AC220; AC708. CAS No. 950769-58-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-13001. | |
| Quizartinib dihydrochloride | Quizartinib dihydrochloride (AC220 dihydrochloride) is the dihydrochloride salt form of Quizartinib (HY-13001). Quizartinib dihydrochloride is an orally active, highly selective and potent second-generation type II FLT3 tyrosine kinase inhibitor, with a K d of 1.6 nM. Quizartinib dihydrochloride inhibits wild-type FLT3 and FLT3-ITD autophosphorylation in MV4-11 cells with IC 50 s of 4.2 and 1.1 nM, respectively. Quizartinib dihydrochloride can be linked to the VHL ligand via an optimized linker to form a PROTAC FLT3 degrader. Quizartinib dihydrochloride induces apoptosis [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AC220 dihydrochloride. CAS No. 1132827-21-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14217. | |
| Q-VD-OPh | Q-VD-OPh is an irreversible pan-caspase inhibitor with potent antiapoptotic properties; inhibits caspase 7 with an IC50 of 48 nM and 25-400 nM for other caspases including caspase 1, 3, 8, 9, 10, and 12. Q-VD-OPh can inhibits HIV infection. Q-VD-OPh is able to cross the blood-brain barrier. Uses: Scientific research. Group: Signaling pathways. Alternative Names: QVD-OPH; Quinoline-Val-Asp-Difluorophenoxymethylketone. CAS No. 1135695-98-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12305. | |
| QX-314 bromide | QX-314 bromide is a membrane-impermeable permanently charged sodium channel blocker [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 24003-58-5. Pack Sizes: 10 mM * 1 mL; 10 mg; 50 mg; 100 mg. Product ID: HY-101350. | |
| QX-314 chloride | QX-314 chloride is a membrane-impermeable permanently charged sodium channel blocker [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 5369-3-9. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-108505. | |
| R110 | R110 is a potent, competitive inhibitor of macrophage migration inhibitory factor 2 (MIF2) tautomerase with an IC 50 of 15 μM. R110 has the potential for the research of cancer diseases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1985622-33-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115887. | |
| R112 | R112 is a fast and reversible inhibitor of spleen tyrosine kinase ( Syk ) kinase. R112 inhibits Syk kinase activity with an IC 50 value of 226 nM and a Ki value of 96 nM. R112 inhibits IgE-FcεRI signaling pathway. R112 can be used for the research of allergic rhinitis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 575474-82-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16420. | |
| (R)-[1,1'-Binaphthalene]-2,2'-diamine | (R)-[1, 1'-Binaphthalene]-2, 2'-diamine is the isomer of (S)-[1, 1'-Binaphthalene]-2, 2'-diamine (HY-W007978A), and can be used as an experimental control. (S)-[1, 1'-Binaphthalene]-2, 2'-diamine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R-(-)-2,2-Diamino-1,1-binaphthyl. CAS No. 18741-85-0. Pack Sizes: 250 mg; 1 g; 5 g. Product ID: HY-W007978. | |
| (R)-1,1'-Binaphthyl-2,2'-diyl hydrogenphosphate | (R)-(-)-1,1'-Binaphthyl-2,2'-diyl Hydrogenphosphate is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 39648-67-4. Pack Sizes: 10 g; 25 g. Product ID: HY-I0718. | |
| R121919 | R121919 (NBI30775) is a potent and selective CRF1R antagonist with a Ki of 2 to 5 nM. R121919 has antidepressant and anxiolytic effects. R121919 alleviates defensive withdrawal in rats[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NBI30775. CAS No. 195055-03-9. Pack Sizes: 10 mM * 1ML; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14127. | |
| (R)-(-)-1,2-Propanediol | (R)-(-)-1,2-Propanediol is a (R)-enantiomer of 1,2-Propanediol that produced from glucose in Escherichia coli expressing NADH-linked glycerol dehydrogenase genes [1]. Uses: Scientific research. Group: Natural products. CAS No. 4254-14-2. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-Z0031. | |
| (R)-(-)-1,3-Butanediol | (R)-(-)-1,3-Butanediol is the R-enantiomer of 1,3-Butanediol (HY-77490A). (R)-(-)-1,3-Butanediol exhibits anti-diabetic property in rats. (R)-(-)-1,3-Butanediol can be used as flavoring and fragrance agents. (R)-(-)-1,3-Butanediol is used to regulate the metabolism of carbohydrate and lipid. [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 6290-3-5. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-77490. | |
| R162 | R162 is a potent inhibitor of glutamate dehydrogenase 1 (GDH1/GLUD1), with anti-cancer properties. Uses: Scientific research. Group: Signaling pathways. CAS No. 64302-87-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103096. | |
| (R)-1-Amino-2-propanol | (R)-1-aminopropan-2-ol is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 2799-16-8. Pack Sizes: 10 mM * 1 mL; 10 g; 25 g. Product ID: HY-W002295. | |
| (R)-1-Boc-3-aminopyrrolidine | (R)-1-Boc-3-aminopyrrolidine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 147081-49-0. Pack Sizes: 5 g; 10 g. Product ID: HY-40097. | |
| (R)-1-Boc-3-methyl-piperazine | (R)-1-Boc-3-methyl-piperazine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 163765-44-4. Pack Sizes: 25 g. Product ID: HY-40041. | |
| R-1 Methanandamide Phosphate | R-1 Methanandamide Phosphate is a water-soluble prodrug analog of arachidonylethanolamide (AEA). AEA is an endogenous cannabinoid compound [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 649569-33-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-126719. | |
| (R,1R)-Tenofovir amibufenamide | (R,1R)-Tenofovir amibufenamide ((R,1R)-HS-10234) can be used for the purifying a tenofovir prodrug. Tynofovir (tenofovir) is a nucleoside acids reverse transcriptase inhibitors [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (R,1R)-HS-10234. CAS No. 1571076-37-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-137453C. | |
| R243 | R243 is a potent and selective CCR8 antagonist. R243 inhibits CCL1/CCR8 interaction and inhibits CCR8 signaling and chemotaxis. R243 has antinociceptive and anti-inflammatory effects[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 688352-84-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122219. | |
| R-268712 | R-268712 is an orally active and selective ALK-5 inhibitor, with an IC50 of 2.5 nM. R-268712 inhibits the phosphorylation of Smad3 in a dose-dependent manner with an IC50 of 10.4 nM. R-268712 suppresses glomerulonephritis as well as glomerulosclerosis by inhibiting TGF-? signaling, which can be used in studies of renal fibrosis and cancer[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 879487-87-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12953. | |
| (R)-(-)-2-Butanol | (R)-(-)-2-Butanol is the isomer of 2-Butanol, which is found in the females of the white grub beetle, Dasylepida ishigakiensis , to attract males. (R)-(-)-2-Butanol is an intermediate of pharmaceutical synthesis by coupling [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 14898-79-4. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-W087952. | |
| (R)-2-Methylpiperazine | (R)-(-)-2-Methylpiperazine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 75336-86-6. Pack Sizes: 25 g. Product ID: HY-34767. | |
| (R)-3-(Boc-amino)pyrrolidine | tert-butyl N-[(3R)-pyrrolidin-3-yl]carbamate is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 122536-77-0. Pack Sizes: 5 g; 10 g. Product ID: HY-W002421. | |
| (R)-3-Fluoropyrrolidine hydrochloride | (R)-3-Fluoropyrrolidine hydrochloride is a derivative of fluorinated pyrrolidines. The amide series of fluorinated pyrrolidines are inhibitors of dipeptidyl peptidase DP-IV. Novel α4β2 receptor ligands characterized by a 3-Fluoropyrrolidine core [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 136725-55-8. Pack Sizes: 1 g; 5 g. Product ID: HY-40421. | |
| (R)-3-Hydroxybutanoic acid | (R)-3-Hydroxybutanoic acid is a metabolite, and converted from acetoacetic acid catalyzed by 3-hydroxybutyrate dehydrogenase. (R)-3-Hydroxybutanoic acid has applications as a nutrition source and as a precursor for vitamins, antibiotics and pheromones [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: (R)-(-)-3-Hydroxybutanoic acid; (R)-3-Hydroxybutyric acid. CAS No. 625-72-9. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-W051723. | |
| (R)-3-Hydroxybutanoic acid sodium | (R)-3-Hydroxybutanoic acid ((R)-3-Hydroxybutyric acid) sodium is a metabolite converted from acetoacetic acid catalyzed by 3-hydroxybutyrate dehydrogenase. (R)-3-Hydroxybutanoic acid sodium can function as a nutrition source, and as a precursor for vitamins, antibiotics and pheromones [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: (R)-(-)-3-Hydroxybutanoic acid sodium; (R)-3-Hydroxybutyric acid sodium. CAS No. 13613-65-5. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-W015851. | |
| (R)-3-Hydroxytetradecanoic acid | (R)-3-Hydroxytetradecanoic acid is an ester product. Uses: Scientific research. Group: Signaling pathways. CAS No. 28715-21-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W288375. | |
| R406 | R406 is an orally available and competitive Syk/FLT3 inhibitor for ATP binding with a Ki of 30 nM, potently inhibits Syk kinase activity in vitro with an IC50 of 41 nM, measured at an ATP concentration corresponding to its Km value. R406 reduces immune complex-mediated inflammation[1]. R406 also inhibits Lyn (IC50=63 nM) and Lck (IC50=37 nM)[2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 841290-81-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12067. | |
| R406 free base | R406 free base is an orally available and competitive Syk/FLT3 inhibitor for ATP binding with a Ki of 30 nM, potently inhibits Syk kinase activity in vitro with an IC50 of 41 nM, measured at an ATP concentration corresponding to its Km value. R406 free base reduces immune complex-mediated inflammation[1]. R406 free base also inhibits Lyn (IC50=63 nM) and Lck (IC50=37 nM)[2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 841290-80-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-11108. | |
| (R)-4-Amino-3-hydroxybutyric acid | (R)-4-Amino-3-hydroxybutyric acid ((R)-GABOB) is a 4-aminobutyric acids ( GABAB ) agonist. (R)-4-Amino-3-hydroxybutyric acid is promising for research of nervous disorders [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (-)-γ-Amino-β-hydroxybutyric acid; (R)-GABOB; (-)-β-Hydroxy-GABA. CAS No. 7013-7-2. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-W005749. | |
| (R)-4-Benzyl-2-oxazolidinone | (R)-4-Benzyl-2-oxazolidinone is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 102029-44-7. Pack Sizes: 10 mM * 1 mL; 5 g; 10 g. Product ID: HY-W007664. | |
| (R)-4-Isopropyloxazolidin-2-one | (R)-4-Isopropyloxazolidin-2-one is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 95530-58-8. Pack Sizes: 10 g; 25 g. Product ID: HY-W002320. | |
| R547 | R547 is a potent, selective and orally active ATP-competitive CDK inhibitor, with Kis of 2 nM, 3 nM and 1 nM for CDK1/cyclin B, CDK2/cyclin E and CDK4/cyclin D1, respectively[1][2][3][4][5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 741713-40-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-10014. | |
| (R)-5,7-Dimethoxyflavanone | (R)-5,7-Dimethoxyflavanone shows potent antimutagenic activity against MeIQ mutagenesis in Ames test using the S. typhimurium TA100 and TA98 strains [1]. And (R)-5,7-Dimethoxyflavanone significantly and dose-dependently inhibits the inflammatory mediato [1]. Uses: Scientific research. Group: Natural products. CAS No. 1277188-85-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N5054. | |
| R 59-022 | R 59-022 (DKGI-I) is a DGK inhibitor (IC50: 2.8 μM). R 59-022 inhibits the phosphorylation of OAG to OAPA. R 59-022 is a 5-HT Receptor antagonist, and activates protein kinase C (PKC). R 59-022 potentiates thrombin-induced diacylglycerol production in platelets and inhibits phosphatidic acid production in neutrophils[1][2][3][4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DKGI-I; Diacylglycerol kinase inhibitor I. CAS No. 93076-89-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107613. | |
| R59949 | R59949 is a pan diacylglycerol kinase (DGK) inhibitor with an IC50 of 300 nM. R59949 strongly inhibits the activity of type I DGK ? and ? and moderately attenuates the activity of type II DGK ? and ?. R59949 activates protein kinase C (PKC) by enhancing the levels of the endogenous ligand diacyl glycerol[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 120166-69-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108355. | |
| R-7050 | R-7050 (TNF-? Antagonist III) is a tumor necrosis factor receptor (TNFR) antagonist with greater selectivity toward TNF?. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TNF-? Antagonist III. CAS No. 303997-35-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110203. | |
| R715 | R715 is a selective bradykinin B1 receptor antagonist. R715 significantly attenuates the hyperalgesic effect developed in Streptozotocin(HY-13753)-diabetic mice [1]. Uses: Scientific research. Group: Peptides. CAS No. 185052-09-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-103290. | |
| R-96544 | R-96544 is an orally active 5-HT 2A receptor antagonist. R-96544 can inhibit platelet aggregation in vitro [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 167144-80-1. Pack Sizes: 5 mg. Product ID: HY-103136. | |
| RA190 | RA190, a bis-benzylidine piperidon, inhibits proteasome function by covalently binding to cysteine 88 of ubiquitin receptor RPN13. Uses: Scientific research. Group: Signaling pathways. CAS No. 1617495-03-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100739. | |
| Rabacfosadine | Rabacfosadine (GS-9219), a novel proagent of the nucleotide analogue PMEG, is designed as a cytotoxic agent that preferentially targets lymphoid cells. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GS-9219; VDC-1101. CAS No. 859209-74-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13640. | |
| Rabeprazole | Rabeprazole (LY307640) is a second-generation proton pump inhibitor ( PPI ) that irreversibly inactivates gastric H + /K + -ATPase. Rabeprazole induces apoptosis. Rabeprazole acts as an uridine nucleoside ribohydrolase ( UNH ) inhibitor with an IC 50 of 0.3 μM. Rabeprazole can be used for the research of gastric ulcerations and gastroesophageal reflux [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY307640. CAS No. 117976-89-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-B0656. | |
| Rabeprazole-d4 | Rabeprazole-d 4 is a deuterium labeled Rabeprazole. Rabeprazole is a second-generation proton pump inhibitor (PPI) that irreversibly inactivates gastric H+/K+-ATPase. Rabeprazole induces apoptosis. Rabeprazole acts as an uridine nucleoside ribohydrolase (UNH) inhibitor with an IC50 of 0.3 μM. Rabeprazole can be used for the research of gastric ulcerations and gastroesophageal reflux[1][2][3]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: LY307640-d4. CAS No. 934295-48-4. Pack Sizes: 1 mg. Product ID: HY-B0656S. | |
| Rabeprazole sodium | Rabeprazole sodium (LY307640 sodium) is a second-generation proton pump inhibitor ( PPI ) that irreversibly inactivates gastric H + /K + -ATPase. Rabeprazole sodium induces apoptosis. Rabeprazole sodium acts as an uridine nucleoside ribohydrolase ( UNH ) inhibitor with an IC 50 of 0.3 μM. Rabeprazole sodium can be used for the research of gastric ulcerations and gastroesophageal reflux [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY307640 sodium. CAS No. 117976-90-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0656A. | |
| Rabusertib | Rabusertib (LY2603618) is a potent and selective inhibitor of Chk1 with an IC50 of 7 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY2603618; IC-83. CAS No. 911222-45-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14720. | |
| (Rac)-1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol sodium | (Rac)-1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol (sodium) is an anionic phospholipid, can be used for drug delivery and the synthesis of liposomes [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 124011-52-5. Pack Sizes: 50 mg; 100 mg. Product ID: HY-112307A. | |
| Rac1-IN-3 | Rac1-IN-3 (Compound 2) is a Rac1 inhibitor with an IC 50 of 46.1 μM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 380470-06-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-156668. | |
| rac-BHFF | rac-BHFF is a potent and orally active allosteric enhancer of GABA B receptor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 123557-91-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103519. | |
| (Rac)-BINAP | (Rac)-BINAP is the isomer of (R)-BINAP (HY-W017757), and can be used as an experimental control. (R)-BINAP is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Signaling pathways. CAS No. 98327-87-8. Pack Sizes: 5 g; 10 g. Product ID: HY-Y0003. | |
| Racecadotril | Racecadotril (Acetorphan) is a neutral endopeptidase ( NEP ) inhibitor. Racecadotril and its active metabolite Thiorphan inhibits purified NEP activity from mouse brain with K i s of 4500 and 6.1 nM, , respectively. Antidiarrheal agent [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Acetorphan. CAS No. 81110-73-8. Pack Sizes: 10 mM * 1 mL; 200 mg; 1 g. Product ID: HY-17399. | |
| (Rac)-JBJ-04-125-02 | (Rac)-JBJ-04-125-02 is the racemate of JBJ-04-125-02. JBJ-04-125-02 is a potent, mutant-selective, allosteric and orally active EGFR inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2140807-05-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135805A. | |
| Raclopride | Raclopride is a dopamine D 2 / D 3 receptor antagonist with potential antipsychotic effects. Raclopride binds to D 2 and D 3 receptor s with K i s of 1.8 nM and 3.5 nM, respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 84225-95-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-103414. | |
| (Rac)-Minzasolmin | (Rac)-Minzasolmin ((Rac)-UCB0599; NPT200-11) is a blood-brain barrier penetrated alpha-synuclein (ASYN) misfolding inhibitor. (Rac)-Minzasolmin acts on the early stage of ASYN aggregation process, by replacing the membrane-bound oligomers ASYN, allowing them to revert to the monomeric form, while preventing pathological aggregation. (Rac)-Minzasolmin effectively improves the ASYN deposition in the retina and the neuro-pathological indicators in two ?-synuclein transgenic mouse models. (Rac)-Minzasolmin can be used for the studies of Parkinson's disease (PD) and dementia with Lewy bodies (DLB)[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (Rac)-UCB0599; NPT200-11. CAS No. 1802518-63-3. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-125287. | |
| (Rac)-Nebivolol | (Rac)-Nebivolol ((Rac)-R 065824) is a racemic isomer of Nebivolol. Nebivolol is a selective β1-adrenergic receptor antagonist with an IC 50 value of 0.8 nM. Nebivolol can prevent up-regulation of Nox2/NADPH oxidase and lipoperoxidation in the early stages of ethanol-induced cardiac toxicity. Vasodilatory activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (Rac)-R 065824. CAS No. 99200-09-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-B0203B. | |
| Racotumomab | Racotumomab (Anti-Human NGcGM3 Recombinant Antibody) is an anti-idiotype monoclonal antibody (MAb). Racotumomab reacts to Neu-glycolyl (NeuGc)-containing gangliosides, sulfatides, and other antigens expressed in tumors. Racotumomab is an active anticancer agent for lung cancer [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: 1E10. CAS No. 946832-34-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99254. | |
| (Rac)-Pyrotinib | (Rac)-Pyrotinib ((Rac)-SHR-1258) is the racemic form of Pyrotinib (HY-104065). Pyrotinib is a potent and selective dual EGFR/HER2 receptor inhibitor. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (Rac)-SHR-1258. CAS No. 1246089-97-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-104065A. | |
| (Rac)-Rhododendrol | (Rac)-Rhododendrol ((Rac)-Betuligenol) is an aromatic compound with pro-oxidant activity. (Rac)-Rhododendrol may be useful in the suppression of liver diseases. (Rac)-Rhododendrol can be toxic to melanocytes, leading to cell death. The metabolite of (Rac)-Rhododendrol, RD-quinone, is cytotoxic and causes enzyme inactivation and endoplasmic reticulum stress by binding to thiol proteins. (Rac)-Rhododendrol-derived melanin exhibits potent pro-oxidant activity and may cause oxidative stress [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (Rac)-Betuligenol. CAS No. 69617-84-1. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-136913. | |
| RAD51-IN-3 | RAD51-IN-3 is a Rad51 inhibitor extracted from patent WO2019051465A1, compound Example 66A [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2301084-99-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136604. | |
| RAD51 Inhibitor B02 | RAD51 Inhibitor B02 (B02) is an inhibitor of human RAD51 with an IC50 of 27.4 ?M. Uses: Scientific research. Group: Signaling pathways. Alternative Names: B02. CAS No. 1290541-46-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101462. | |
| Radafaxine hydrochloride | Radafaxine hydrochloride (GW-353162A) is a DAT (dopamine transporter) and NET(norepinephrine transporter) transporters inhibitor, and nAChR family modulator. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (S,S)-Hydroxybupropion hydrochloride; GW-353162A; BW-306U. CAS No. 106083-71-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-17590. | |
| Rademikibart | Rademikibart (CBP-201) is a human monoclonal antibody targeting IL-4Rα with a KD of 20.7 pM when binding to human IL-4Rα epitopes. Rademikibart does not bind to IL-4Rα from other species. Rademikibart inhibits IL-4 and IL-13-mediated STAT6 signaling, TF-1 cell proliferation and TARC production in PBMCs. Rademikibart has the potential for moderate-to-severe Th2 inflammatory diseases research [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: CBP-201. CAS No. 2648260-80-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990090. | |
| Radicicol | Radicicol is an inhibitor of Hsp90 with an IC 50 value < 1 μM, and leads to proteasomal degradation [1]. Radicicol exhibits inhibition on PDK with IC 50 s of 230 μM ( PDK1 ) and 400 μM ( PDK3 ). Radicicol is an antifungal and antimalarial antibiotic, impairs mitochondrial replication by targeting P. falciparum topoisomerase VIB [2]. Radicicol is also an inhibitor of fat mass and obesity-associated protein ( FTO ), with an IC 50 value of 16.04 μM [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Monorden. CAS No. 12772-57-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N6769. | |
| Radiprodil | Radiprodil (RGH-896) is an orally active and selective NMDA NR2B antagonist. A potential therapeutic agent in treatment of neuropathic pain and possibly other chronic pain conditions [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RGH-896. CAS No. 496054-87-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14777. | |
| Radotinib | Radotinib(IY-5511) is a novel and selective BCR-ABL1 tyrosine kinase inhibitor with IC50 of 34 nM for wild-type BCR-ABL1 kinase. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IY-5511. CAS No. 926037-48-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15728. | |
| RAF265 | RAF265 is a potent and orally active RAF/VEGFR2 inhibitor. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CHIR-265. CAS No. 927880-90-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-10248. | |
| Raffinose | Raffinose (Melitose), a non-digestible short-chain oligosaccharide, is a trisaccharide composed of galactose, glucose, and fructose and can be found in many plants. Raffinose (Melitose) can be hydrolyzed to D-galactose and sucrose by the enzyme α-galactosidase (α-GAL) [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Melitose. CAS No. 512-69-6. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-N7088. | |
| Rafigrelide | Rafigrelide is a platelet-lowering agent, and also has antithrombotic properties. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 3,3-Dimethylanagrelide. CAS No. 1029711-88-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-U00383. | |
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