MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Ptaquiloside | Ptaquiloside is a sesquiterpene glycoside isolated from Pteridium aquilinum var.latiusculum and has carcinogenic activity [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Braxin C; Aquilide A. CAS No. 87625-62-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N7882. |  |
| PTBP1-RNA-binding inhibitor P6 TFA | PTBP1-RNA-binding inhibitor P6 (PTBP1 ?3-helix derived peptide P6) TFA is a stapled peptide inhibitor of the splicing factor PTBP1, which inhibits alternative splicing events regulated by PTBP1. PTBP1 binds RNA through its RNA recognition motif[1]. Uses: Scientific research. Group: Peptides. Alternative Names: PTBP1 ?3-helix derived peptide P6 TFA. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P5960. | |
| PTC-028 | PTC-028 is an orally bioavailable inhibitor of stem cell factor BMI-1 in ovarian cancer. PTC-028 selectively inhibits cancer cells whereas normal cells remain unaffected. PTC-028 downregulates BMI-1, inducing caspase-mediated apoptosis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1782970-28-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103696. | |
| PTC-209 | PTC-209 is a specific BMI-1 inhibitor with an IC 50 of 0.5 μM in HEK293T cell line. PTC-209 irreversibly impairs colorectal cancer-initiating cells (CICs). PTC-209 shows potent anti-myeloma activity and impairs the tumor microenvironment [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 315704-66-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15888. | |
| PTC-209 hydrobromide | PTC-209 hydrobromide is a specific BMI-1 inhibitor with an IC 50 of 0.5 μM in HEK293T cell line. PTC-209 hydrobromide irreversibly impairs colorectal cancer-initiating cells (CICs). PTC-209 hydrobromide shows potent anti-myeloma activity and impairs the tumor microenvironment [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1217022-63-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15888A. | |
| PTC258 | PTC258 is a specific and orally active splicing modulator of Elongator complex protein 1 gene (ELP1). PTC258 increases the expression of ELP1 in vitro and in vivo. PTC258 is well tolerated in mouse model[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2476724-74-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-148772. | |
| PTC299 | PTC299 is an orally active inhibitor of VEGFA mRNA translation that selectively inhibits VEGF protein synthesis at the post-transcriptional level. PTC299 is also a potent inhibitor of dihydroorotate dehydrogenase (DHODH). PTC299 shows good oral bioavailability and lack of off-target kinase inhibition and myelosuppression. PTC299 can be useful for the research of hematologic malignancies [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1256565-36-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-124593. | |
| PTCDA | PTCDA is an organic dye molecule and an organic semiconductor [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 128-69-8. Pack Sizes: 100 g. Product ID: HY-W011009. | |
| PtdIns-(345)-P3 (12-dipalmitoyl) (sodium) | PtdIns-(345)-P3 (12-dipalmitoyl) sodium (Phosphatidylinositol tris-3,4,5-phosphate, 1,2-dipalmitoyl sodium) is a phosphatidylinositol 3,4,5-trisphosphate (PIP3) analog. PtdIns-(345)-P3 (12-dipalmitoyl) sodium can be incorporated in liposomes establish a backdrop of membrane phospholipids that closely mirrors in vivo conditions [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Phosphatidylinositol tris-3,4,5-phosphate, 1,2-dipalmitoyl sodium. CAS No. 1628353-02-5. Pack Sizes: 100 μg; 500 μg; 1 mg. Product ID: HY-148971A. | |
| Pterin-6-carboxylic acid | Pterin-6-carboxylic acid serves as a precursor for the formation of folate, which plays a critical role in cell growth, development, and repair. Pterine-6-carboxylic acid has been studied for its potential as a fluorescent dye [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 948-60-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-W037823. | |
| Pteroic acid | Pteroic acid is an active compound. Uses: Scientific research. Group: Signaling pathways. CAS No. 119-24-4. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-79139. | |
| Pterostilbene | Pterostilbene is a stilbenoid isolated from blueberries and Pterocarpus marsupium [1]. Shows anti-oxidant, anti-inflammatory, anti-carcinogenic, anti-diabetic and anti-obesity properties [1] [4]. Pterostilbene blocks ROS production [3] , also exhibits inhibitory activity against various free radicals such as DPPH, ABTS, hydroxyl, superoxide and hydrogen peroxide [4]. Uses: Scientific research. Group: Natural products. CAS No. 537-42-8. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-N0828. | |
| p-Terphenyl | p-Terphenyl is a p-terphenyl that can be isolated from Aspergillus of the genus Thelephora. p-Terphenyl showed significant anti-tumor and anti-metastatic effects in xenograft models of gastric and pancreatic cancer. Derivatives of p-Terphenyl also have anti-inflammatory or anti-proliferative effects [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 92-94-4. Pack Sizes: 5 g; 25 g. Product ID: HY-W013973. | |
| pTH (1-34) amide (human) | pTH (1-34) amide (human) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development [1]. Uses: Scientific research. Group: Peptides. CAS No. 83139-29-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P4821. | |
| pTH (39-84) (human) | pTH (39-84) (human) is a parathyroid hormone (PTH) C-terminal fragment. pTH (39-84) (human) stimulates osteoclast formation [1]. Uses: Scientific research. Group: Peptides. CAS No. 90880-43-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P10078. | |
| pTH-Related Protein (1-34) (human,mouse,rat) | pTH-Related Protein (1-34) (human, mouse, rat), a fragment of parathyroid hormone-related protein, is an anabolic agent. pTH-Related Protein (1-34) (human, mouse, rat) can be used for postmenopausal osteoporosis study [1]. Uses: Scientific research. Group: Peptides. Alternative Names: pTHrP (1-34). CAS No. 112540-82-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P3075. | |
| PTIO | PTIO is a specific scavenger of NO and redox mediator. PTIO reacts with NO to form the corresponding imino nitroxides and NO 2. PTIO enhances organic contaminants oxidation by permanganate [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 18390-00-6. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-131898. | |
| p-Tolualdehyde | p-Tolualdehyde is the active small molecule, that could used as drug intermediate [1]. Uses: Scientific research. Group: Natural products. CAS No. 104-87-0. Pack Sizes: 10 mM * 1 mL; 10 g; 25 g. Product ID: HY-W012860. | |
| p-Toluenesulfonamide | p-Toluenesulfonamide is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 70-55-3. Pack Sizes: 100 g. Product ID: HY-79602. | |
| p-Toluenesulfonic acid monohydrate | p-Toluenesulfonic acid (PTSA) monohydrate, a strong organic acid, acts as organic catalyst used in organic synthesis [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PTSA monohydrate. CAS No. 6192-52-5. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-W015175. | |
| p-Toluic acid | p-Toluic acid (4-Methylbenzoic acid), coumarin, is a substituted benzoic acid. p-Toluic acidis synthetic p-aminomethylbenzoic acid (PAMBA), intermediates such as p-toluonitrile. p-Toluic acidMay have potential reproductive toxicity, press 1g/kgRepeated administration of doses can produce a variety of adverse effects on the epididymis [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: 4-Methylbenzoic acid. CAS No. 99-94-5. Pack Sizes: 10 mM * 1 mL; 5 g. Product ID: HY-76547. | |
| p-Tolylmaleimide | p-Tolylmaleimide (compound 9) is a naphthalimide derivative that has cytotoxic effects on cancer cells. p-Tolylmaleimide can arrest the cell cycle of human acute myeloid leukemia cells K562 in the sub-G0/G1 phase and induce apoptosis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1631-28-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129592. | |
| PTP1B-IN-2 | PTP1B-IN-2 is a potent protein tyrosine phosphatase 1B (PTP1B) inhibitor with an IC50 of 50 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1919853-46-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100462. | |
| PTP1B-IN-3 | PTP1B-IN-3 is a potent and orally active PTP1B inhibitor with IC 50 s of 120 nM for both PTP1B and TCPTP. PTP1B-IN-3 has antidiabetic and anticancer effects [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 809272-64-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-15133. | |
| PTP1B-IN-3 diammonium | PTP1B-IN-3 diammonium is a potent and orally active PTP1B inhibitor with IC 50 s of 120 nM for both PTP1B and TCPTP. PTP1B-IN-3 diammonium has antidiabetic and anticancer effects [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2702673-78-5. Pack Sizes: 1 mg. Product ID: HY-15133A. | |
| PTPN22-IN-1 | PTPN22-IN-1 is a potent PTPN22 inhibitor (IC50=1.4 μM; Ki=0.50 μM). PTPN22-IN-1 exhibits >7-10 fold selectivity for PTPN22 over similar phosphatases. PTPN22-IN-1 augments antitumor immune responses[1]. From WO2021007491A1 compound L-1. Uses: Scientific research. Group: Signaling pathways. CAS No. 2580935-57-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139693. | |
| p-Tyramine-d4 hydrochloride | p-Tyramine-d4 (hydrochloride) is the deuterium labeled Tyramine hydrochloride. Tyramine hydrochloride is an amino acid that helps regulate blood pressure. Tyramine hydrochloride occurs naturally in the body, and it's found in certain foods[1][2]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 1189884-47-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-W016823S. | |
| PU139 | PU139 is a potent pan-histone acetyltransferase (HAT) inhibitor. PU139 blocks the HATs Gcn5, p300/CBP-associated factor (PCAF), CREB (cAMP response element-binding) protein (CBP) and p300 with IC50s of 8.39, 9.74, 2.49 and 5.35 ?M, respectively[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 158093-65-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-124696. | |
| PU.1-IN-1 | PU.1-IN-1 (compound A11) is a potent PU.1 inhibitor with an IC50 of 2 nM. PU.1-IN-1 has anti-inflammatory properties[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 873588-27-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-W176171. | |
| PU 23 | PU 23 is a non-carboxylic multidrug resistance protein 4 ( MRP4 ) inhibitor as an active agent reducing resistance to anticancer agent 6-Mercaptopurine [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 817635-93-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136217. | |
| Pucotenlimab | Pucotenlimab (HX008) is a humanized immunoglobulin G4 (IgG4) anti programmed cell death protein 1 (anti-PD-1) monoclonal antibody. Pucotenlimab can be used for the research of tumor [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: HX008. CAS No. 2403647-03-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99938. | |
| Puerarin | Puerarin is an isoflavone extracted from Pueraria root and is a 5-HT2C receptor antagonist. Puerarin inhibits the dorsal motor nucleus of the vagus (DMV)-vagus nerve pathway, which in turn leads to decreased fat absorption [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. CAS No. 3681-99-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0145. | |
| Pulcherriminic acid | Pulcherriminic acid is a cyclic dipeptide antimicrobial agent with high affinity for Fe3+, found mainly in Bacillus and yeast. Pulcherriminic acid chelates iron ions through a non-enzymatic reaction to form the extracellular red pigment pulcherrimin, which competes for iron nutrition and thus achieves an antibacterial effect. Pulcherriminic acid has great applications in food, agriculture and medical industries[1][2]. Uses: Scientific research. Group: Natural products. CAS No. 957-86-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N10473. | |
| Pulegone | Pulegone, the major chemical constituent of Nepeta cataria essential oil which is an aromatic herb, is one of avian repellents [1]. The molecular target for the repellent action of Pulegone in avian species is nociceptive TRP ankyrin 1 (TRPA1). Pulegone stimulates both TRPM8 and TRPA1 channel in chicken sensory neurons and suppresses the former but not the latter at high concentrations [2]. Uses: Scientific research. Group: Natural products. CAS No. 89-82-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-N1500. | |
| Pullulanase | Pullulanase (R-enzyme) is a starch debranching enzyme, is often used in biochemical studies. Pullulanase hydrolyses the α-1,6 glucosidic linkages in starch, amylopectin, pullulan, and related oligosaccharides. Pullulanase converts polysaccharide into small fermentative sugars during saccharification [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R-enzyme. CAS No. 9075-68-7. Pack Sizes: 1 g; 5 g; 10 g. Product ID: HY-P3173. | |
| Pullulan, Viscosity(10%):15-180mPa.s | Pullulan (Pullulan standard 5800) (Mw 362-480 kDa; Mn 100-200 kDa) is a class of orally active and water-soluble linear glucosic polysaccharide. Pullulan can be isolated from the polymorphic fungus Aureobasidium pullulans. Pullulan is composed of maltotriose repeating units linked by ?-1,6 linkages and is an amorphous slime matter. Pullulan is widely used in food, environment, pharmaceutical, manufacturing, and electronics[1][2][3][4]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 9057-2-7. Pack Sizes: 10 g; 25 g. Product ID: HY-W145522. | |
| Pumaprazole | Pumaprazole is a reversible proton pump antagonist. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BY-841. CAS No. 158364-59-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19223. | |
| Pumitamig | Pumitamig is a bispecific antibody that targets both PD-L1 and VEGF-A. Pumitamig can be used for the study of solid tumors[1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: PM-8002; BNT-327. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P991097. | |
| Pumosetrag Hydrochloride | Pumosetrag Hydrochloride (MKC-733; DDP-733) is an orally available 5-HT3 partial agonist developed for the treatment of irritable bowel syndrome and gastroesophageal reflux disease. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MKC-733; DDP-733. CAS No. 194093-42-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19650. | |
| Punicalagin | Punicalagin is a polyphenol ingredient isolated from Pomegranate ( Punica granatum L.) or the leaves of Terminalia catappa L. Punicalagin is a reversible and non-competitive 3CL pro inhibitor and inhibits SARS-CoV-2 replication in vitro. Punicalagin is an anti-hepatitis B virus (HBV) agent and has antioxidant, anti-inflammatory, and anticancer effects. Punicalagin has the potential for the research of COVID-19 [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 65995-63-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 20 mg. Product ID: HY-N0063. | |
| Punicalin | Punicalin is a species that can be isolated from the leaves of Punica granatum. Punicalin is an active molecule against hepatitis b virus (HBV). Punicalin can induce pyroptosis. Punicalin is a Carbonic anhydrase inhibitor. Punicalin blocks the binding of S-glycoprotein and ACE2 receptors. Pnuicalin has anti-inflammatory, antioxidant and antiviral activity[1][2][3][4][5][6][7]. Uses: Scientific research. Group: Natural products. CAS No. 65995-64-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N0639. | |
| Punicic acid | Punicic acid is a bioactive compound of pomegranate seed oil. Punicic acid is an isomer of conjugated α-linolenic acid and ω-5 polyunsaturated fatty acids. Punicic acid has anti-inflammatory and antioxidant activities and can inhibit the expression of inflammatory mediators such as tumor necrosis factor α ( TNF-α ). Punicic acid can also reduce the formation of β-amyloid deposits and hyperphosphorylation of tau by increasing the expression of GLUT4 protein and inhibiting the overactivation of calpain , and is used to prevent and treat neurodegenerative diseases. In addition, punicic acid also has breast cancer inhibitor properties that depend on lipid peroxidation and PKC pathways [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Trichosanic acid. CAS No. 544-72-9. Pack Sizes: 1 mg (35.92 mM * 100 μL in Methanol). Product ID: HY-139066. | |
| Purine | Purine is an endogenous metabolite. Purine bases are the building blocks of the nucleic acids. Purine inhibits the activation of PARP. Purine protects against oxidant-induced cell injury. Purine can be used in the research of cancer and nervous system diseases [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Purine (6CI,8CI); 3,5,7-Triazaindole; 3H-Imidazo[4,5-d]pyrimidine; 6H-Imidazo[4,5-d]pyrimidine; 7H-Purine; Isopurine; NSC 753; β-Purine. CAS No. 120-73-0. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-34431. | |
| Purine nucleoside phosphorylase, Microorganism | Purine nucleoside phosphorylase, Microorganism (PNP) is a key enzyme in purine metabolism, which is involved in the purine rescue pathway. The deficiency of Purine nucleoside phosphorylase resulted in impaired T cell function. In the presence of inorganic orthophosphate as the second substrate, Purine nucleoside phosphorylase catalyzes the breaking of the glycosidic bond between ribose and deoxyribonucleoside to generate purine base and ribose (deoxyribose) -1-phosphate [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PNP. CAS No. 9030-21-1. Pack Sizes: 100 U. Product ID: HY-P2724. | |
| Purmorphamine | Purmorphamine is a smoothened/Smo receptor agonist with an EC 50 of 1 μM. Uses: Scientific research. Group: Signaling pathways. CAS No. 483367-10-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-15108. | |
| Puromycin | Puromycin dihydrochloride is the dihydrochloride salt of puromycin. Puromycin is an aminoglycoside antibiotic that inhibits protein synthesis. Uses: Scientific research. Group: Natural products. Alternative Names: CL13900. CAS No. 53-79-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg. Product ID: HY-B1743. | |
| Puromycin aminonucleoside | Puromycin aminonucleoside (NSC 3056) is the aminonucleoside portion of the antibiotic puromycin, and used in nephrosis animal models [1]. Puromycin aminonucleoside induces apoptosis [2]. Puromycin aminonucleoside is a reversible inhibitor of dipeptidyl peptidase II and cytosol alanyl aminopeptidase [3]. Puromycin aminonucleoside induces secretion of cell migrasome [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NSC 3056. CAS No. 58-60-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-15695. | |
| Puromycin dihydrochloride | Puromycin dihydrochloride (CL13900 dihydrochloride), an aminonucleoside antibiotic, inhibits protein synthesis [1]. Uses: Scientific research. Group: Natural products. Alternative Names: CL13900 dihydrochloride. CAS No. 58-58-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-B1743A. | |
| Purpurin | Purpurin is a natural anthraquinone compound from Rubia cordifolia L. Purpurin has antidepressant-like effects [1]. Uses: Scientific research. Group: Natural products. CAS No. 81-54-9. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-N0571. | |
| Purpurogallin | Purpurogallin is a naturally phenol extracted from the plants of Quercus spp, has potent xanthine oxidase (XO) inhibitory activity with an IC 50 of 0.2 μM. Purpurogallin has antioxidant and anti-inflammatory effects [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 569-77-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-12136. | |
| Purvalanol A | Purvalanol A is a potent CDK inhibitor, which inhibits cdc2-cyclin B, cdk2-cyclin A, cdk2-cyclin E, cdk4-cyclin D1, and cdk5-p35 with IC50s of 4, 70, 35, 850, 75 nM, resepctively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NG-60. CAS No. 212844-53-6. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18299A. | |
| Purvalanol B | Purvalanol B (NG 95) is a potent, selective, reversible and ATP-competitive inhibitor CDK, with IC50s of 6 nM, 6 nM, 9 nM, 6 nM for cdc2-cyclin B, CDK2-cyclin A, CDK2-cyclin E and CDK5-p35, respectively. Purvalanol B shows selectivity for CDK over a range of other protein kinases (IC50>1000 nM). Purvalanol B inhibits the growth a chloroquine-resistant strain of P. falciparum[1][1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NG 95. CAS No. 212844-54-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-18299. | |
| PU-WS13 | PU-WS13 is a selective Grp94 inhibitor, with an EC50 of 0.22 ?M. Uses: Scientific research. Group: Signaling pathways. CAS No. 1454619-14-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-18680. | |
| Puxitatug | Puxitatug is an immunoglobulin G1-?, anti-[Homo sapiens VTCN1 (Vset domain containing T cell activation inhibitor 1, B7 family member H4, B7H4, B7-H4)] Homo sapiens monoclonal antibody[1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: INT-016. CAS No. 2760250-47-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990059. | |
| PW0787 | PW0787 is a potent, selective, orally active, and brain-penetrant GPR52 agonist (EC50=135 nM). PW0787 suppresses psychostimulant behavior[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2624131-45-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138639. | |
| PX-12 | PX-12(IV-2) is an irreversible inhibitor of Thioredoxin-1 (Trx-1); inhibits the growth of MCF-7 and HT-29 cells with IC50 values of 1.9 and 2.9 ?M, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IV-2. CAS No. 141400-58-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13734. | |
| PX-478 | PX-478 is an orally active HIF-1α inhibitor with potent antitumor activities. PX-478 can cross the blood-brain barrier [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 685898-44-6. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10231. | |
| PXS-5505 anhydrous | PXS-5505 anhydrous (LOX-IN-3 dihydrochloride) is an orally active lysyl oxidase (LOX) inhibitor. PXS-5505 anhydrous can be used for fibrosis, cancer and angiogenesis research[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LOX-IN-3 dihydrochloride. CAS No. 2409964-23-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138625A. | |
| PXYC1 | PXYC1 is a ribosomal protein S1 ( RpsA ) antagonist with K d s of 0.81 and 0.31 μM for RpsA-CTD and RpsA-CTD Δ438A, respectively. RpsA plays an important role in the trans-translation process of Mycobacterium Tuberculosis (Mtb) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 865098-81-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-146446. | |
| PY159 | PY159 is a humanized antibody expressed in CHO cells, targeting TREM1/CD354. PY159 carries a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 143.66 kDa. The isotype control for PY159 can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001). Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2359413-58-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990650. | |
| PY-60 | PY-60 is a robust and specific activator of YAP transcriptional activity that targets annexin A2 (ANXA2) with a Kd of 1.4 μM. PY-60 directly binds to ANXA2 and antagonizes its normal cellular function of repressing YAP activity[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2765218-56-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141644. | |
| PYBG | PYBG acts as a versatile precursor to be facilely conjugated with various fluorescent dyes through ‘Click chemistry and Sonogashira coupling reactions [1]. PYBG is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Fluorescent dye. CAS No. 680622-71-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-23926. | |
| PYCR1-IN-1 | PYCR1-IN-1 (compound 4) is a pyrroline-5-carboxylate reductase 1 (PYCR1) inhibitor with an IC50 of 8.8 μM. PYCR1-IN-1 has anticancer effects[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 709-85-3. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126271. | |
| pyCTZ | pyCTZ (Pyridyl CTZ), a pyridyl Coelenterazine (CTZ) analog, and is an ATP-independent pyridyl substrate of LumiLuc luciferase. pyCTZ generates strong blue bioluminescence in the presence of luciferases. pyCTZ can be used for aequorin-based calcium sensing [1]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Pyridyl CTZ. CAS No. 2125486-34-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135367. | |
| Pymetrozine | Pymetrozine is a feeding inhibitor of Homoptera, in preventing transmission of cauliflower mosaic caulimovirus by the aphid species Myzus persicae (Sulzer). Uses: Scientific research. Group: Signaling pathways. Alternative Names: CGA 215944. CAS No. 123312-89-0. Pack Sizes: 10 mM * 1 mL; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-B0821. | |
| Pyocyanin | Pyocyanin (Pyocyanine) is a toxic, quorum sensing (QS) controlled metabolite produced by Pseudomonas aeruginosa. Pyocyanin is a REDOX active compound that promotes the production of reactive oxygen species (ROS). Pyocyanin has antibacterial and anti-inflammatory activity [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Pyocyanine; Sanazin; Sanasin. CAS No. 85-66-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111278. | |
| Pyoluteorin | Pyoluteorin is an antibiotic that inhibits Oomycete fungi , including the plant pathogen Pythium ultimum , and suppresses plant diseases caused by this fungus [1]. Pyoluteorin induces human triple-negative breast cancer MDA-MB-231 cells apoptosis in vitro. Pyoluteorin can be used for the research of human triple-negative breast cancer [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 25683-07-2. Pack Sizes: 1 mg. Product ID: HY-114979. | |
| PYR01 | PYR01 is a non-nucleoside reverse transcriptase inhibitor and a killing activator targeting HIV infected cells. PYR01 has cytokilling and antiviral properties of HIV-1 infection with the IC50 values of 27.5nM and 39.7nM, respectively. PYR01 leads to selective cytotoxicity by promoting HIV-1 Gag-Pol dimerization and HIV-1 protease intracellular activation. PYR01 can be used in the study of HIV[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2560576-15-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-153225. | |
| Pyr10 | Pyr10 is a pyrazole derivative and a selective TRP cation 3 (TRPC3) inhibitor. Pyr10 inhibits Ca2+ influx in carbachol-stimulated TRPC3-transfected HEK293 cells with an IC50 of 0.72 ?M (IC50 of 13.08 ?M for store operated Ca2+ entry in BRL-2H3 cells). Pyr10 has the ability to distinguish between receptor-operated TRPC3 and native stromal interaction molecule 1 (STIM1)/Orai1 channels[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1315323-00-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-19408. | |
| [Pyr1]-Apelin-13 | [Pyr1]-Apelin-13 is a highly potent, selective endogenous apelin receptor (APJ) agonist. Uses: Scientific research. Group: Peptides. Alternative Names: [pGlu1]-Apelin-13. CAS No. 217082-60-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1033. | |
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