MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Tucidinostat | Tucidinostat (Chidamide) is a potent and orally bioavailable HDAC enzymes class I ( HDAC1/2/3 ) and class IIb ( HDAC10 ) inhibitor, with IC 50 s of 95, 160, 67 and 78 nM, less active on HDAC8 and HDAC11 ( IC 50 s, 733 nM, 432 nM, respectively), and shows no effect on HDAC4/5/6/7/9 [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Chidamide; HBI-8000; CS 055. CAS No. 1616493-44-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109015. |  |
| Tuftsin | Tuftsin is a tetrapeptide. Tuftsin is a macrophage/microglial activator. Uses: Scientific research. Group: Peptides. CAS No. 9063-57-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P0240. | |
| TUG-891 | TUG-891 is a potent and selective agonist for the long chain free fatty acid (LCFA) receptor 4 ( FFA4/GPR120 ) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1374516-07-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-100881. | |
| Tulathromycin A | Tulathromycin A (Tulathromycin), a macrolide antibiotic , inhibits protein synthesis (IC 50 =0.26 μM) by targeting bacterial ribosome. Tulathromycin A is used for the research of respiratory disease in cattle and swine. Immunomodulatory effects [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Tulathromycin; CP 472295. CAS No. 217500-96-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15662. | |
| Tulisokibart | Tulisokibart (PRA023) is a humanized IgG1-κ monoclonal antibody. Tulisokibart targets to TNFSF15 /TL1A. Tulisokibart can be used to study a variety of inflammatory/fibrotic diseases, such as Crohn's Disease (CD) and ulcerative colitis [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: PRA023; PRA-023. CAS No. 2648504-55-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990007. | |
| Tulobuterol | Tulobuterol (C-78 free base) is a long-acting β 2 -adrenoceptor agonist, which reduces the frequency of exacerbations of chronic obstructive pulmonary disease and bronchial asthma. Tulobuterol is also a sympathomimetic agent used as a transdermal patch, and increases normal diaphragm muscle strength [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: C-78 free base. CAS No. 41570-61-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B1810. | |
| Tulobuterol hydrochloride | Tulobuterol hydrochloride (C-78) is a long-acting β 2 -adrenoceptor agonist, which reduces the frequency of exacerbations of chronic obstructive pulmonary disease and bronchial asthma. Tulobuterol hydrochloride is also a sympathomimetic agent used as a transdermal patch, increases normal diaphragm muscle strength [1]. Tulobuterol hydrochloride inhibit rhinovirus replication and modulate airway inflammation [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: C-78. CAS No. 56776-01-3. Pack Sizes: 10 mM * 1 mL; 250 mg; 500 mg. Product ID: HY-W011733. | |
| Tunlametinib | Tunlametinib, an antineoplastic agent, is a MEK1/2 inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HL-085. CAS No. 1801756-06-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132844. | |
| Turanose | Turanose is an isomer of Sucrose that naturally exists in honey. Turanose has anti-inflammatory and regulates adipogenesis effect. Turanose has potential for obesity and related chronic diseases research [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 547-25-1. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-113334. | |
| Turkesterone | Turkesterone is a potent ecdysteroid. Turkesterone acts as an ecdysteroid receptor ( EcR ) agonist in some insect systems [1]. Uses: Scientific research. Group: Natural products. CAS No. 41451-87-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N2548. | |
| Tusamitamab | Tusamitamab is an IgG1 monoclonal antibody that targets CEACAM5. Tusamitamab can be used to synthesize Tusamitamab ravtansine (SAR408701), which is a first-in-class humanized antibody-drug conjugate (ADC) that combines Tusamitamab and DM4 (a potent maytansine derivative) [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2349294-95-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99054. | |
| Tusamitamab ravtansine | Tusamitamab ravtansine (SAR-408701) is a targeted ADC against tumor cells expressing CEACAM5 , composed of a humanized anti-CEACAM5 monoclonal antibody covalently linked to the potent cytotoxic agent, maytansinoid DM4 (HY-12454), via a cleavable linker. Tusamitamab ravtansine has an average drug-to-antibody ratio (DAR) of 3.8 [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: SAR-408701; HuMAb2-3-SPDB-DM4. CAS No. 2254086-60-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99542. | |
| Tuspetinib | Tuspetinib (HM43239) is an orally active and selective FLT3 inhibitor with IC 50 s of 1.1 nM, 1.8 nM and 1.0 nM for FLT3 WT, FLT3 internal tandem duplication (ITD) and FLT3 D835Y kinases, respectively. Tuspetinib inhibits the kinase activity of FLT3 as a reversible type I inhibitor and modulates p-STAT5, p-ERK, SYK, JAK1/2, and TAK1. Tuspetinib inhibits the proliferation and induces the apoptosis of leukemic cells [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HM43239. CAS No. 2294874-49-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145015. | |
| Tuvusertib | Tuvusertib (M1774; ATR inhibitor 1) is a selective and orally active ATR inhibitor extracted from patent WO2015187451A1, compound I-l, with a K i value below 1 μΜ [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: M1774; ATR inhibitor 1. CAS No. 1613200-51-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111451. | |
| TW-37 | TW-37 is a potent Bcl-2 inhibitor with K i values of 260, 290 and 1110 nM for Mcl-1 , Bcl-2 and Bcl-xL , respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 877877-35-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-12020. | |
| Tween 20 | Tween 20 (Polysorbate 20) is a polyoxyethylene (POE)-type nonionic surfactant [1] [2] [3]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Polysorbate 20. CAS No. 9005-64-5. Pack Sizes: 100 mL. Product ID: HY-141415. | |
| Tween 80 | Tween 80 (Polysorbate 80), a surfactant, has been widely used as a solvent for pharmacological experiments. Tween 80 can also reduce bacterial attachment and inhibit biofilm formation. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Polysorbate 80. CAS No. 9005-65-6. Pack Sizes: 50 mL; 100 mL. Product ID: HY-Y1891. | |
| TWS119 | TWS119 is an inhibitor of GSK-3β , with an IC 50 of 30 nM, and activates the wnt/β-catenin pathway. Uses: Scientific research. Group: Signaling pathways. CAS No. 601514-19-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10590. | |
| TXA707 | TXA707, the active metabolite of TXA-709, is an FtsZ inhibitor with antibacterial activity. TXA707 is promising for research of S. aureus infections [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1609670-89-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153695. | |
| Tyk2-IN-19 | Tyk2-IN-19 (compound 1) is an orally active and blood-brain barrier (BBB) permeable Tyk2 inhibitor. Tyk2-IN-19 can be used for study of neurodegenerative diseases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2866415-98-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-161683. | |
| Tylosin | Tylosin (Tylosin A) is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin is widely used as a feed additive for promoting animal growth. Tylosin is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 1401-69-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0519A. | |
| Tylosin phosphate | Tylosin phosphate is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin tartrate exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin phosphate is widely used as a feed additive for promoting animal growth. Tylosin phosphate is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 1405-53-4. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-B0519B. | |
| Tylosin tartrate | Tylosin tartrate is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin tartrate exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin tartrate is widely used as a feed additive for promoting animal growth. Tylosin tartrate is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 74610-55-2. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B0519. | |
| Tyloxapol | Tyloxapol is a nonionic liquid polymer of the alkyl aryl polyether alcohol type, used as a surface active stabilizer. Tyloxapol is used to induce hyperlipidemia in animals [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 25301-02-4. Pack Sizes: 500 mg; 1 g. Product ID: HY-B1068. | |
| Tylvalosin | Tylvalosin (Acetylisovaleryltylo sin) is an orally active, broad-spectrum macrolide antibiotic with antimicrobial activity. Tylvalosin is an antiviral agent used to study PRRSV infection. Tylvalosin induces apoptosis. Tylvalosin also has anti-inflammatory activity, alleviates oxidative stress, and alleviates acute lung injury by inhibiting NF-κB activation [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Acetylisovaleryltylo?sin. CAS No. 63409-12-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-128423A. | |
| Tylvalosin tartrate | Tylvalosin (Acetylisovaleryltylosin) tartrate is an orally active, broad-spectrum macrolide antibiotic with antimicrobial activity. Tylvalosin tartrate is an antiviral agent useful in studying PRRSV infection. Tylvalosin tartrate induces apoptosis. Tylvalosin tartrate also has anti-inflammatory activity, relieves oxidative stress, and alleviates acute lung injury by inhibiting NF-κB activation [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Acetylisovaleryltylo?sin tartrate. CAS No. 63428-13-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg. Product ID: HY-128423. | |
| [Tyr8]-Substance P | [Tyr8]-Substance P is an active peptide. [Tyr8]-Substance P can be used for the research of various biochemical [1]. Uses: Scientific research. Group: Peptides. CAS No. 55614-10-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P2784. | |
| TYRA-300 | TYRA-300 is an orally active, selective inhibitor for FGFR3 with an IC 50 of 11 nM in Ba/F3. TYRA-300 exhibits antitumor efficacy against urothelial cancers and solid tumors [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2800223-30-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-159642. | |
| Tyramine | Tyramine is an amino acid that helps regulate blood pressure. Tyramine occurs naturally in the body, and it's found in certain foods [1]. Uses: Scientific research. Group: Natural products. CAS No. 51-67-2. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-W007606. | |
| Tyramine hydrochloride | Tyramine hydrochloride is an amino acid that helps regulate blood pressure. Tyramine hydrochloride occurs naturally in the body, and it's found in certain foods [1]. Uses: Scientific research. Group: Natural products. CAS No. 60-19-5. Pack Sizes: 10 mM * 1 mL; 250 mg; 500 mg. Product ID: HY-W016823. | |
| Tyrosinase-IN-12 | Non-competitive tyrosinase inhibitor (Tyrosinase-IN-12) is a potent, non-competitive tyrosinase inhibitor with an IC 50 value of 49.33 ± 2.64 μM and K i value of 31.25 ± 0.25 μM. Non-competitive tyrosinase inhibitor (Tyrosinase-IN-12) have the highest radical scavenging activity to reduce the production of reactive oxygen species ( ROS ) with an IC 50 value of 25.39 ± 0.77 μM. Non-competitive tyrosinase inhibitor (Tyrosinase-IN-12) can be used for anti-browning substances in the food and agricultural sectors [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1860779-42-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-149404. | |
| Tyrosinase, Mushroom | Tyrosinase (EC 1.14.18.1) (Polyphenol oxidase) is a rate-limiting enzyme that controls the production of melanin and is encoded by TYR gene. Tyrosinase is mainly found in melanosomes synthesized by skin melanocytes [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Polyphenol oxidase. CAS No. 9002-10-2. Pack Sizes: 1 KU; 5 KU. Product ID: HY-125860. | |
| Tyrosine decarboxylase, Microorganism | Tyrosine decarboxylase, Microorganism (TDC) widely exists in plants, insects and different microorganisms, and is often used in biochemical research. Tyrosine decarboxylase is a pyridoxal 5'-phosphate (PLP)-dependent decarboxylase that catalyzes the removal of carboxyl groups from tyrosine to produce tyramine and carbon dioxide [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TDC; TyrDC. CAS No. 9002-9-9. Pack Sizes: 25 U. Product ID: HY-P2825. | |
| Tyrosine kinase-IN-7 | Tyrosine kinase-IN-7 (compound 13h) is an inhibitor of the tyrosine kinase EGFR. The IC 50 s for inhibiting EGFR(WT) and EGFR(T790M) are 0.630 μM and 0.956 μM respectively. Tyrosine kinase-IN-7 has antitumor activity against four cancer cell lines (HepG2, HCT-116, MCF-7, and A431) with IC 50 s of 13.02 μM, 10.14 μM, 12.68 μM, and 47.05 μM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 345615-74-9. Pack Sizes: 10 mg. Product ID: HY-156912. | |
| Tyrosine kinase inhibitor | Tyrosine kinase inhibitor is a potent tyrosine kinase inhibitor. Uses: Scientific research. Group: Signaling pathways. CAS No. 1021950-26-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-10421. | |
| Tyrosol | Tyrosol is a derivative of phenethyl alcohol. Tyrosol attenuates pro-inflammatory cytokines from cultured astrocytes and NF-κB activation. Anti-oxidative and anti-inflammatory effects [1]. Uses: Scientific research. Group: Natural products. CAS No. 501-94-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg. Product ID: HY-N0474. | |
| Tyrosol (Standard) | Tyrosol (Standard) is the analytical standard of Tyrosol. This product is intended for research and analytical applications. Tyrosol is a derivative of phenethyl alcohol. Tyrosol attenuates pro-inflammatory cytokines from cultured astrocytes and NF-κB activation. Anti-oxidative and anti-inflammatory effects [1]. Uses: Scientific research. Group: Natural products. CAS No. 501-94-0. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-N0474R. | |
| Tyrosylleucine | Tyrosylleucine (Tyr-Leu, YL), an orally active dipeptide, exhibits a potent antidepressant-like activity [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Tyr-Leu. CAS No. 17355-10-1. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122794. | |
| Tyrosylleucine TFA | Tyrosylleucine (Tyr-Leu, YL) TFA, an orally active dipeptide, exhibits a potent antidepressant-like activity [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Tyr-Leu TFA. CAS No. 66852-01-5. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122794A. | |
| Tyrothricin | Tyrothricin is a polypeptide antibiotic mixture isolated from Bacillus brevis and consists of tyrocidines and gramicidins. Tyrothricin shows activity against bacteria , fungi and some viruses. Tyrothricin containing formulations are used in sore throat agents and in agents for the healing of infected superficial and small-area wounds [1]. Uses: Scientific research. Group: Natural products. CAS No. 1404-88-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-120435. | |
| Tyrphostin A51 | Tyrphostin A51 is a potent protein tyrosine kinase (PTK) inhibitor. Tyrphostin A51 inhibits the volume-dependent release of [ 3 H]taurine in a dose-dependent manner. Tyrphostin A51 markedly reduces cellular tyrosyl phosphorylation level. Tyrphostin A51 inhibits both basal and EGF-induced human bone cell proliferation [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AG-183. CAS No. 126433-07-6. Pack Sizes: 1 mg. Product ID: HY-101960A. | |
| Tyrphostin AG 879 | Tyrphostin AG 879 (AG 879) is a tyrosine kinase inhibitor that inhibits TrKA phosphorylation ( IC 50 of 10 μM), but not TrKB and TrKC. Tyrphostin AG 879 is also a selective ErbB2 tyrosine kinase inhibitor with an IC 50 of 1 μM, and has at least 500-fold higher selectivity to ErbB2 than EGFR. Tyrphostin AG 879 has anticancer activity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AG 879. CAS No. 148741-30-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-20878. | |
| U0124 | U0124, an inactive U0126 analog, has no effect on c-Fos and c-Jun protein or mRNA levels. U0126 is a MEK inhibitor. U0124 does not inhibit MEK at concentrations up to 100 μM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 108923-79-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107621. | |
| U0126 | U0126 is a potent, non-ATP competitive and selective MEK1 and MEK2 inhibitor, with IC 50 s of 72 nM and 58 nM, respectively. U0126 is an autophagy and mitophagy inhibitor [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 109511-58-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-12031A. | |
| U-46619 | U-46619 (9,11-Methanoepoxy PGH2) is a stable analogue of Thromboxane A2 (HY-113350) (TXA2) and acts as a potent TXA2 (TP) agonist. U-46619 also is a RhoA agonist. U-46619 stimulates the activation of RhoA through TXA2 receptor activation [1] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 9,11-Methanoepoxy PGH2. CAS No. 56985-40-1. Pack Sizes: 1 mg (28.5 mM * 100 μL in Methyl acetate); 5 mg (28.5 mM * 500 μL in Methyl acetate). Product ID: HY-108566. | |
| (-)-U-50488 hydrochloride | (-)-U-50488 hydrochloride ((-)-Trans-(1S,2S)-U-50488 hydrochloride) is a selective kappa-opioid receptor (KOR) agonist (b>K d=2.2 nM) over μ-opioid receptor (MOR) (b>K d =430 nM). (-)-U-50488 hydrochloride is a more active enantiomer than (+) trans-(1R,2R) U-50488 (HY-15997A) or the (±) trans-racemic mixture U-50488 (HY-15997B). (-)-U-50488 hydrochloride has a potent and sustained anti- HIV effect in fected blood monocyte-derived macrophages (MDM) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (-)-Trans-(1S,2S)-U-50488 hydrochloride. CAS No. 114528-79-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-15997. | |
| (±)-U-50488 hydrochloride | (±)-U-50488 ((±)-Trans-(1R,2R)-U-50488) hydrochloride is a selective κ opioid receptor (KOR) agonist [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (±)-Trans-(1R,2R)-U-50488 hydrochloride. CAS No. 67197-96-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-15997B. | |
| U-69593 | U-69593 is a potent and selective κ1-opioid receptor agonist [1]. U-69593 attenuates addictive agent-induced behavioral sensitization in the rat [2]. U-69593 reduces anxiety and enhances spontaneous alternation memory in mice [3]. U-69593 reduces calcium-dependent dialysate levels of dopamine and glutamate in the ventral striatum [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 96744-75-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-12363. | |
| U-73122 | U-73122 is a phospholipase C (PLC) and 5-LO (5-lipoxygenase) inhibitor with an IC 50 of 1-2.1 μM for PLC. Uses: Scientific research. Group: Signaling pathways. CAS No. 112648-68-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13419. | |
| U-73343 | U-73343, works as a protonophore, is an inactive analog of U-73122 and can be used as a negative control. U-73343 dose-dependently inhibits acid secretion irrespective of the stimulant. U-73122 is a phospholipase C (PLC) and 5-LO (5-lipoxygenase) inhibitor with an IC 50 of 1-2.1 μM for PLC [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 142878-12-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-108630. | |
| U-74389G | U-74389G (PNU74389G meleate) is an antioxidant , can inhibit lipid peroxidation reactions. U-74389G can protect against ischemia-reperfusion injury and be widely used in animal models of ischemic injury and hypertension. U-74389G shows anti-inflammatory activity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PNU74389G (meleate). CAS No. 153190-29-5. Pack Sizes: 10 mg; 25 mg. Product ID: HY-106592A. | |
| U-83836E | U-83836E (PNU-83836E) is a compound with anti-inflammatory and antioxidant activities that reduces lung inflammation inhibiting oxidative stress and ROS production. U-83836E has shown potential for treating asthma and lung inflammation in animal models [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PNU-83836E. CAS No. 137018-55-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-117762. | |
| U-99194 maleate | U-99194 maleate is a potent and selective Dopamine3 Receptor (D3 receptor) antagonist. U-99194 maleate also enhances prolactin secretion and striatal dopamine synthesis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: U-99194A; PNU-99194A maleate; JPC-211 maleate. CAS No. 234757-41-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-12701A. | |
| UAU | UAU (UpApU) is a trinucleotide that is identified as the RNA codon for tyrosine, which is involved in protein synthesis. UAU can be used in research about the interaction between RNA codons, tRNAs, and ribosomes [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: UpApU. CAS No. 752-71-6. Pack Sizes: 1 mg. Product ID: HY-159807. | |
| Ubamatamab | Ubamatamab (REGN4018) is a humanized bispecific antibody targeted against Mucin 16 (MUC16) and CD3. Ubamatamab demonstrates potent antitumor activity [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: REGN4018. CAS No. 2305629-50-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99539. | |
| Ublituximab | Ublituximab (LFB-R603; TG-1101; TGTX-1101) is a next-generation, type 1 chimeric monoclonal antibody targeting a unique epitope on the CD20 antigen. Ublituximab has anticancer effects [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: LFB-R603; TG-1101; TGTX-1101. CAS No. 1174014-05-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99538. | |
| Ubrogepant | Ubrogepant (MK-1602) is an orally active and selective antagonist of calcitonin gene-related peptide receptor ( CGRP ). Ubrogepant has high affinity for CGRP receptors in human and rhesus monkeys, and can effectively block the cAMP response stimulated by α-CGRP. Ubrogepant can be used in the study of acute migraine [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-1602. CAS No. 1374248-77-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12366. | |
| Ucenprubart | Ucenprubart is an anti- CD200R1 human IgG4κ monoclonal antibody [1]. Recommend Isotype Controls: Human IgG4 kappa, Isotype Control (HY-P99003). Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2414559-57-0. Pack Sizes: 1 mg. Product ID: HY-P990770. | |
| Ucf-101 | Ucf-101 is a selective and competitive inhibitor of pro-apoptotic protease Omi/HtrA2 , with an IC 50 of 9.5 μM for His-Omi. Ucf-101 exhibits very little activity against various other serine proteases (IC 50 >200 μM). Ucf-101 has a natural red fluorescence at 543 nm that is used to monitor its ability to enter mammalian cells. Ucf-101 has a significant cardioprotective effect against MI/R injury and also has certain neuroprotective effect [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 313649-08-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-125959. | |
| Udenafil | Udenafil (DA8159) is a potent, selective and orally active phosphodiesterase type 5 (PDE5) inhibitor. Udenafil also inhibits cGMP hydrolysis and can be used for erectile dysfunction research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DA8159. CAS No. 268203-93-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18253. | |
| Udonitrectag | Udonitrectag (REC 0559), a low molecular weight compound that mimics NGF, aims to address the issue of NGF stability [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: REC 0559. CAS No. 1458063-04-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109194. | |
| UDP-Galactose disodium | UDP-Galactose disodium is a natural agonist of the P2Y 14 receptor with an EC 50 of 0.67 μM for the hP2Y 14 receptor. UDP-Galactose disodium is a substrate for the transferase beta-1, 4 galactosyltransferase V ( B4GALT5 ). In addition, UDP-Galactose disodium is required for the biosynthesis of several abundant glycoconjugates that form the surface glycocalyx of Leishmania major [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 137868-52-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114364. | |
| UDP-GalNAc disodium | UDP-GalNAc (UDP-N-acetyl-D-galactosamine) disodium is a sugar nucleotide and a substrate of EpsC115. EpsC115 is an exopolymeric substances (EPS) N-terminal deletion mutant with the residue 1-115 deletion. UDP-GalNAc UDP-GalNAc is the donor substrate of many N-acetylgalactosaminyltransferases, enzymes which transfer GalNAc from the nucleotide sugar to a saccharide or peptide acceptor [1]. Uses: Scientific research. Group: Natural products. Alternative Names: UDP-N-acetyl-D-galactosamine disodium. CAS No. 108320-87-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-114365. | |
| UDP-GlcNAz disodium | UDP-GlcNAz disodium is a substrate for UDP-GlcNAc:polypeptidyltransferase [1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 1611490-64-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145934A. | |
| UGT1A1-IN-1 | UGT1A1-IN-1 (compound 2) is a non-competitive inhibitor of UGT1A1 , which can inhibit the 1-O-glucuronidation process mediated by UGT1A1 with a K i value of 5.02 μM. UGT1A1-IN-1 (compound 2) can bind on UGT1A1 at the same ligand-binding site as bilirubin (HY-N0323). UGT1A1-IN-1 can serve as a turn-on fluorescent probe substrate for UGT1A1 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2097024-37-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-160250. | |
| UK122 | UK122 is a potent and selective urokinase-type plasminogen activator (uPA) inhibitor with an IC 50 of 0.2 μM. UK122 shows no or little inhibition of tissue-type PA (tPA), plasmin, thrombin, and trypsin (all IC 50 >100 μM). UK122, 4-oxazolidinone analogue, is an anticancer agent and inhibits cancer cell migration and invasion [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 940290-58-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111056. | |
| UK-5099 | UK-5099 (PF-1005023) is a potent inhibitor of the mitochondrial pyruvate carrier ( MPC ). UK-5099 (PF-1005023) inhibits pyruvate-dependent O 2 consumption with an IC 50 of 50 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PF-1005023. CAS No. 56396-35-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15475. | |
| UK-78282 hydrochloride | UK-78282, a novel piperidine, potent and selective Kv1.3 blocker with an IC 50 of 200 nM. UK-78,282 effectively suppresses human T-lymphocyte activation in vitro. UK-78,282 binds to residues at the inner surface of the channel overlapping the site of action of verapamil [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 136647-02-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-W013727. | |
| Ulifloxacin | Ulifloxacin is a broad-spectrum quinolone antibiotic. Ulifloxacin is the active metabolite of Prulifloxacin (HY-B0024). Ulifloxacin has anti-bacterial activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 112984-60-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-108279. | |
| Uliledlimab | Uliledlimab is a potent against CD73 humanizedized monoclonal antibody. Uliledlimab inhibits the conversion of extracellular adenosine monophosphate (AMP) to adenosine. Uliledlimab can be used in research of cancer [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: TJ004309. CAS No. 2378407-27-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99169. | |
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