MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Pralsetinib | Pralsetinib (BLU-667) is a highly potent, selective RET inhibitor. Pralsetinib (BLU-667) inhibits WT RET, RET mutants V804L, V804M, M918T and CCDC6-RET fusion with IC 50 s of 0.4, 0.3, 0.4, 0.4, and 0.4 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BLU-667. CAS No. 2097132-94-8. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-112301. |  |
| Pramipexole | Pramipexole is a selective and blood-brain barrier (BBB) penetrant dopamine D2-type receptor agonist, with K i s of 2.2 nM, 3.9 nM, 0.5 nM and 1.3 nM for D2-type receptor, D 2 , D 3 and D 4 receptors, respectively. Pramipexole can be used for the research of Parkinson's disease (PD) and restless legs syndrome (RLS) [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 104632-26-0. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-B0410. | |
| Pramipexole dihydrochloride | Pramipexole dihydrochloride is a selective and blood-brain barrier (BBB) penetrant dopamine D2-type receptor agonist, with K i s of 2.2 nM, 3.9 nM, 0.5 nM and 1.3 nM for D2-type receptor, D 2 , D 3 and D 4 receptors, respectively. Pramipexole dihydrochloride can be used for the research of Parkinson's disease (PD) and restless legs syndrome (RLS) [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 104632-25-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17355. | |
| Pramipexole dihydrochloride hydrate | Pramipexole dihydrochloride hydrate is a selective and blood-brain barrier (BBB) penetrant dopamine D2-type receptor agonist, with K i s of 2.2 nM, 3.9 nM, 0.5 nM and 1.3 nM for D2-type receptor, D 2 , D 3 and D 4 receptors, respectively. Pramipexole dihydrochloride hydrate can be used for the research of Parkinson's disease (PD) and restless legs syndrome (RLS) [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 191217-81-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-B0410A. | |
| Pramiracetam | Pramiracetam (CI-879 free base) is a PREP (prolyl endopeptidase) inhibitor. Pramiracetam improves cognitive impairment caused by traumatic brain injury. Pramiracetam can be used in the study of neurodegenerative diseases [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CI-879 free base. CAS No. 68497-62-1. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-17455. | |
| Pramlintide | Pramlintide is a polypeptide analogue of human amylin. Pramlintide, an antidiabetic agent, is antineoplastic in colorectal cancer [1]. Uses: Scientific research. Group: Peptides. CAS No. 151126-32-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P0058. | |
| Pramlintide acetate | Pramlintide acetate is a polypeptide analogue of human amylin. Pramlintide acetate, an antidiabetic agent, is antineoplastic in colorectal cancer [1]. Uses: Scientific research. Group: Peptides. CAS No. 187887-46-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P0058B. | |
| Pramocaine hydrochloride | Pramocaine hydrochloride decreases the permeability of neuronal membranes to sodium ions, blocking both initiation and conduction of nerve impulses. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Pramoxine hydrochloride. CAS No. 637-58-1. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-B1319. | |
| Pranazepide | Pranazepide (FR120480) is a cholecystokinin-A receptor antagonist [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FR120480. CAS No. 150408-73-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-105257. | |
| Pranidipine | Pranidipine (OPC-13340) is a potent, long acting 1,4-dihydropyridine calcium channel blocker with antihypertensive activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: OPC-13340. CAS No. 99522-79-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19664. | |
| Pranlukast | Pranlukast is a highly potent, selective and competitive antagonist of peptide leukotriene s. Pranlukast inhibits [ 3 H]LTE 4 , [ 3 H]LTD 4 , and [ 3 H]LTC 4 bindings to lung membranes with K i s of 0.63±0.11, 0.99±0.19, and 5640±680 nM, respectively. Uses: Scientific research. Group: Natural products. Alternative Names: ONO-1078. CAS No. 103177-37-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0290. | |
| Pranoprofen | Pranoprofen is a non-steroidal anti-inflammatory agent ( NSAID ) for the research of keratitis or other ophthalmology diseases. Pranoprofen inhibit COX-1 and COX-2 enzymes, thus blocking arachidonic acid converted to eicosanoids and reducing prostaglandins synthesis [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 52549-17-4. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B0336. | |
| Prasinezumab | Prasinezumab (PRX 002) is a humanized IgG1 monoclonal antibody directed against aggregated α-synuclein. Prasinezumab has the potential for Parkinson's disease research [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: PRX 002; RG 7935; RO 7046015. CAS No. 1960462-19-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99405. | |
| Prasugrel | Prasugrel (PCR 4099), a thienopyridine and proagent, inhibits platelet function. Prasugrel is an orally active and potent P2Y12 receptor antagonist, and inhibits ADP-induced platelet aggregation [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PCR 4099. CAS No. 150322-43-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-15284. | |
| Prasugrel hydrochloride | Prasugrel hydrochloride (PCR 4099 hydrochloride), a thienopyridine and proagent, inhibits platelet function. Prasugrel hydrochloride is an orally active and potent P2Y12 receptor antagonist, and inhibits ADP-induced platelet aggregation [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PCR 4099 hydrochloride. CAS No. 389574-19-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-15284A. | |
| Pravastatin sodium | Pravastatin sodium (CS-514 sodium) is an HMG-CoA reductase inhibitor against sterol synthesis with IC 50 of 5.6 μM. Uses: Scientific research. Group: Natural products. Alternative Names: CS-514 sodium. CAS No. 81131-70-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-B0165A. | |
| Pravastatin (sodium) (Standard) | Pravastatin (sodium) (Standard) is the analytical standard of Pravastatin (sodium). This product is intended for research and analytical applications. Pravastatin sodium (CS-514 sodium) is an HMG-CoA reductase inhibitor against sterol synthesis with IC 50 of 5.6 μM. Uses: Scientific research. Group: Natural products. Alternative Names: CS-514 (sodium) (Standard). CAS No. 81131-70-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0165AR. | |
| Praziquantel | Praziquantel is a broadly effective trematocide and cestocide, the initial effect of praziquantel on the schistosome may be an interaction of the drug with lipid constituents of the tegumental membrane. Praziquantel is used for the research of schistosomiasis [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 55268-74-1. Pack Sizes: 10 mM * 1 mL; 500 mg; 5 g. Product ID: HY-B0244. | |
| Prazobind | Prazobind (SZL 49), a prazosin analog, is a potent alpha 1-adrenoceptor blocker. Prazobind competes for alpha 1-adrenoceptor binding sites with a similar potency (IC 50 =1 nM) in tissues enriched in both the alpha 1A (hippocampus) and alpha 1B (liver) subtypes [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SZL 49. CAS No. 107021-36-3. Pack Sizes: 1 mg. Product ID: HY-118335. | |
| Prazosin | Prazosin is an α-adrenergic receptor antagonist. Prazosin can reduce inflammation, relieve anxiety, alleviate panic, prevent memory decline, and modulate the pain-relieving effects of opioids. Prazosin can be used in the study of hypertension and Alzheimers disease [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 19216-56-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-B0193. | |
| Prazosin-d8 | Prazosin-d 8 is the deuterium labeled Prazosin. Prazosin is an alpha-adrenergic blocker and is a sympatholytic drug used to treat high blood pressure and anxiety, PTSD, and panic disorder. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 1006717-55-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-B0193S. | |
| Prazosin-d8 hydrochloride | Prazosin-d8 hydrochloride is the deuterium labeled Prazosin hydrochloride. Prazosin hydrochloride is an alpha-adrenergic blocker [1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 1189508-34-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-B0193AS. | |
| Prazosin hydrochloride | Prazosin hydrochloride is a well-tolerated, CNS-active α1-adrenergic receptor antagonist for the research of high blood pressure and alcohol use disorders [1]. Prazosin hydrochloride potently inhibits Norepinephrine (NE)-stimulated 45Ca efflux with an IC 50 of 0.15 nM [2].Prazosin hydrochloride inhibits organic cation transporters OCT-1 and OCT-3 with IC 50 s of 1.8, and 13 μM, respectively [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 19237-84-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg. Product ID: HY-B0193A. | |
| PRDX1-IN-1 | PRDX1-IN-1 is a selective inhibtor of PRDX1 with an IC50 value of 0.164 ?M. PRDX1-IN-1 can be used in researches related to cancer.PRDX1-IN-1 promots intracellular ROS accumulation, and inhibits the proliferation, invasion and migration of cancer cells besides inducing apoptosis. PRDX1-IN-1 could be used in cancer research[1]. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 5 mg; 10 mg. Product ID: HY-149394. | |
| PRE-084 hydrochloride | PRE-084 hydrochloride is a highly selective σ1 receptor ( S1R ) agonist, with an IC 50 of 44 nM. PRE-084 hydrochloride exhibits good neuroprotective effects, can improve motor function and motor neuron survival in mice. PRE-084 hydrochloride also can ameliorate myocardial ischemia-reperfusion injury in rats by activating the Akt-eNOS pathway [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 75136-54-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-18100A. | |
| Preclamol hydrochloride | Preclamol hydrochloride ((-)-3-PPP hydrochloride) is a selective dopamine autoreceptor agonist. Preclamol hydrochloride has the potential for the research of schizophrenia [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (-)-3-PPP hydrochloride. CAS No. 88768-67-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108698. | |
| Prednicarbate | Prednicarbate is a topical corticosteroid agent. Prednicarbate can be used for the research of inflammatory skin diseases, such as atopic dermatitis [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 73771-04-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1365. | |
| Prednisolone | Prednisolone is a potent, orally active corticosteroid and a glucocorticoid. Prednisolone possesses about four times the anti-inflammatory activity of hydrocortisone while causing less salt and water retention. Prednisolone can be used for ocular, anti-inflammatory research [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 50-24-8. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-17463. | |
| Prednisolone acetate | Prednisolone acetate (Prednisolone 21-acetate) is an adrenocortical hormone active molecule with various pharmacological effects such as anti-inflammatory, anti-allergic, and immune suppression. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Prednisolone 21-acetate. CAS No. 52-21-1. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg; 500 mg. Product ID: HY-B1214. | |
| Prednisolone hemisuccinate | Prednisolone hemisuccinate is a synthetic glucocorticoid, a derivative of cortisol, which is used to treat a variety of inflammatory and auto-immune conditions. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Prednisolone 21-hemisuccinate. CAS No. 2920-86-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 250 mg. Product ID: HY-B1087. | |
| Prednisolone (Standard) | Prednisolone (Standard) is the analytical standard of Prednisolone. This product is intended for research and analytical applications. Prednisolone is a potent, orally active corticosteroid and a glucocorticoid. Prednisolone possesses about four times the anti-inflammatory activity of hydrocortisone while causing less salt and water retention. Prednisolone can be used for ocular, anti-inflammatory research [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 50-24-8. Pack Sizes: 100 mg; 250 mg. Product ID: HY-17463R. | |
| Prednisolone Tebutate | Prednisolone tebutate is a synthetic glucocorticoid used as an antiinflammatory and immunosuppressant. Uses: Scientific research. Group: Signaling pathways. CAS No. 7681-14-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-U00098. | |
| Prednisone | Prednisone (Adasone) is a corticosteroid agent with anti-inflammatory and immunosuppressive effects that can be used to study diseases related to systemic lupus erythematosus [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Dehydrocortisone. CAS No. 53-03-2. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0214. | |
| Prednisone acetate | Prednisone acetate (Prednisone 21-acetate), a glucocorticoid, is an orally active Notch inhibitor. Prednisone acetate has anti-inflammatory activity and can enhance the immune response [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Prednisone 21-acetate. CAS No. 125-10-0. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-B1832. | |
| Pregn-5-en-3β-ol | Pregn-5-en-3β-ol, a steroid compound, when formulated as the biscarboxylic acid hemiesters along with androst-5-en-3β-ol, serves as a potent positive allosteric modulator of NMDA (N-methyl-D-aspartate) receptors, making it applicable for research into psychiatric disorders [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2862-58-0. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-W882667. | |
| Pregnanediol | Pregnanediol is the major metabolite of progesterone and can be excreted via urine. Pregnanediol offers an indirect way to measure progesterone levels in vivo [1]. Uses: Scientific research. Group: Natural products. Alternative Names: NSC 1612; NSC 47462. CAS No. 80-92-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-107850. | |
| Pregnanediol 3-glucuronide | Pregnanediol 3-glucuronide is the major terminal metabolite of progesterone, playing an important role in physiological processes, such as the female menstrual cycle, pregnancy (supports gestation), embryogenesis and maternal immune response of humans and other species [1]. Uses: Scientific research. Group: Natural products. CAS No. 1852-49-9. Pack Sizes: 5 mg. Product ID: HY-W040047. | |
| Pregnant mare serum gonadotropin | Pregnant mare serum gonadotropin (PMSG) is a gonadotropin used to promote follicular development and ovulation in animals. PMSG exerts its regulatory effects by stimulating changes in blood hormones, gonadotropins, and cytoplasmic estradiol receptors in the anterior pituitary and hypothalamus. PMSG is commonly used in livestock to improve reproductive efficiency and can also be utilized for research on estrous cycle regulation [1]. Uses: Scientific research. Group: Natural products. Alternative Names: PMSG. CAS No. 9002-70-4. Pack Sizes: 1 KU. Product ID: HY-N12634. | |
| Pregnenolone | Pregnenolone (3β-Hydroxy-5-pregnen-20-one) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone acts as a signaling-specific inhibitor of cannabinoid CB1 receptor , inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone can protect the brain from cannabis intoxication [1] [2]. Pregnenolone is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels [3]. Uses: Scientific research. Group: Natural products. Alternative Names: 3β-Hydroxy-5-pregnen-20-one. CAS No. 145-13-1. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0151. | |
| Pregnenolone 16α-carbonitrile | Pregnenolone 16α-carbonitrile is an orally active prototypical and effective rodent-PXR activator. Pregnenolone 16α-carbonitrile, a synthetic steroid, induces cytochrome P450 3A expression. Pregnenolone 16α-carbonitrile exhibits increased resistance to subsequent stressful insults [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1434-54-4. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-131723. | |
| Pregnenolone monosulfate sodium | Pregnenolone monosulfate sodium (3?-Hydroxy-5-pregnen-20-one monosulfate sodium) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone monosulfate sodium acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone monosulfate sodium can protect the brain from cannabis intoxication[1][2]. Pregnenolone monosulfate sodium is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels[3]. Uses: Scientific research. Group: Natural products. Alternative Names: 3?-Hydroxy-5-pregnen-20-one monosulfate sodium. CAS No. 1852-38-6. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110189. | |
| Pregnenolone (Standard) | Pregnenolone (Standard) is the analytical standard of Pregnenolone. This product is intended for research and analytical applications. Pregnenolone (3β-Hydroxy-5-pregnen-20-one) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone acts as a signaling-specific inhibitor of cannabinoid CB1 receptor , inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone can protect the brain from cannabis intoxication [1] [2]. Pregnenolone is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels [3]. Uses: Scientific research. Group: Natural products. Alternative Names: 3β-Hydroxy-5-pregnen-20-one (Standard). CAS No. 145-13-1. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0151R. | |
| Preladenant | Preladenant is a potent and competitive antagonist of the human adenosine A2A receptor with a K i of 1.1 nM and has over 1000-fold selectivity over other adenosine receptors. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SCH-420814. CAS No. 377727-87-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10889. | |
| Prenalterol | Prenalterol is a selective β1-adrenergic receptor agonist. Prenalterol has no effect on gut smooth muscle contractile activity. Prenalterol can be used for researching cardiovascular disease [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 57526-81-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-112071. | |
| Prepro-Atrial Natriuretic Factor (26-55) (human) | Prepro-Atrial Natriuretic Factor (26-55) (human) is a polypeptide that increases renal cortical and medullary cyclic GMP levels. Prepro-Atrial Natriuretic Factor (26-55) (human) increases renal guanylate cyclase activity [1]. Uses: Scientific research. Group: Peptides. CAS No. 112160-82-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P4811. | |
| preQ1 dihydrochloride | preQ1 dihydrochloride is a modified, guanine-derived nucleobase and a precursor of Queuine (HY-N10574) biosynthesis. preQ1 dihydrochloride binds to the aptamer of PreQ1 riboswitch with high affinity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 86694-45-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115642. | |
| Presatovir | Presatovir (GS-5806) is an orally bioavailable RSV fusion inhibitor with a mean EC 50 value of 0.43 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GS-5806. CAS No. 1353625-73-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16727. | |
| Pretilachlor | Pretilachlor is a herbicide used to control the the most common weeds found in paddy rice crops [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 51218-49-6. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B2035. | |
| Pretomanid | Pretomanid (PA-824) is an antibiotic used for the research of multi-drug-resistant tuberculosis affecting the lungs. Pretomanid exhibits a sub-micromolar MIC against M. tuberculosis (MTB). The MIC values of PA-824 against a panel of MTB pan-sensitive and Rifampin mono-resistant clinical isolates range from 0.015 to 0.25 μg/mL. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PA-824; (S)-PA 824. CAS No. 187235-37-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10844. | |
| Prexasertib | Prexasertib (LY2606368) is a selective, ATP-competitive second-generation checkpoint kinase 1 (CHK1) inhibitor with a K i of 0.9 nM and an IC 50 of <1 nM. Prexasertib inhibits CHK2 (IC 50 =8 nM) and RSK1 (IC 50 =9 nM). Prexasertib causes double-stranded DNA breakage and replication catastrophe resulting in apoptosis. Prexasertib shows potent anti-tumor activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY2606368. CAS No. 1234015-52-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18174. | |
| Prexasertib dihydrochloride | Prexasertib dihydrochloride (LY2606368 dihydrochloride) is a selective, ATP-competitive second-generation checkpoint kinase 1 (CHK1) inhibitor with a K i of 0.9 nM and an IC 50 of <1 nM. Prexasertib dihydrochloride inhibits CHK2 (IC 50 =8 nM) and RSK1 (IC 50 =9 nM). Prexasertib dihydrochloride causes double-stranded DNA breakage and replication catastrophe resulting in apoptosis. Prexasertib dihydrochloride shows potent anti-tumor activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY2606368 dihydrochloride. CAS No. 1234015-54-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18174A. | |
| Prezalumab | Prezalumab (AMG 557) is a humanized IgG2 monoclonal antibody targeting ICOSL. Prezalumab inhibits T cell activation and related immune responses by binding to ICOSL and blocking the interaction between ICOS and ICOSL. Prezalumab can be used in the research of autoimmune diseases and inflammatory diseases such as systemic lupus erythematosus. Recommend Isotype Controls: Human IgG2 kappa, Isotype Control (HY-P99002)[1][2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: AMG 557. CAS No. 1523164-68-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99414. | |
| Pridinol mesylate | Pridinol mesylate is an orally active, blood-brain permeable, muscarinic acetylcholine receptor (mAChR) -directed muscle relaxant. Pridinol mesylate reduces the conduction of impulses to spinal motor neurons and exerts muscle relaxant activity. Pridinol mesylate inhibits skeletal muscle contractures in diseases of both central and peripheral origin and can be used in research in the field of musculoskeletal diseases [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 6856-31-1. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B1343. | |
| Pridopidine | Pridopidine, a dopamine ( DA ) stabilizer, acts as a low affinity dopamine D2 receptor ( D2R ) antagonist. Pridopidine exerts high affinity towards sigma 1 receptor ( S1R ) with K i between 70 and 80 nM, which is ~100× higher than its affinity toward D2R. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ACR16; ASP2314; FR310826. CAS No. 346688-38-8. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10684. | |
| Prifetrastat | KAT6-IN-1 (compound E) is a potent inhibitor of histone acetyltransferases KAT6A and KAT6B. KAT6-IN-1 can be used in cancer research[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2569008-99-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153444. | |
| Prilocaine | Prilocaine, an amino amide, is a Na/K-ATPase inhibitor. Prilocaine has neurotoxic effects [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 721-50-6. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B0137. | |
| PRIMA-1 | PRIMA-1 (NSC-281668) is a mutant p53 reactivator, restores the sensitivity of TP53 mutant-type thyroid cancer cells to the histone methylation inhibitor 3-Deazaneplanocin A. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NSC-281668. CAS No. 5608-24-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-19980A. | |
| Primaquine | Primaquine is a potent antimalaria agent and a potent gametocytocide in falciparum malaria. Primaquine prevents relapse in vivax and ovale malaria [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 90-34-6. Pack Sizes: 10 mM * 1 mL; 50 mg. Product ID: HY-12651A. | |
| Primidone | Primidone is the orally active inhibitor for TRPM3 ( IC 50 = 0.6 μM), RIP kinase and voltage-gated sodium channel , and the antagonist for GABA receptor. Primidone can be used as the analgesic and anticonvulsant agent [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 125-33-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B0339. | |
| Primidone-d5 | Primidone-d 5 is the deuterium labeled Primidone. Primidone is a potent anticonvulsant agent of the barbiturate class. Primidone is a neuronal voltage-gated sodium channel (VGSC) blocker and can be used for the study of epilepsy, essential tremor, and Psychiatric disorders[1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 73738-06-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-B0339S. | |
| Primidone (Standard) | Primidone (Standard) is the analytical standard of Primidone. This product is intended for research and analytical applications. Primidone is a potent anticonvulsant agent of the barbiturate class. Primidone is a neuronal voltage-gated sodium channel (VGSC) blocker and can be used for the study of epilepsy, essential tremor, and Psychiatric disorders [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 125-33-7. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-B0339R. | |
| Prim-O-glucosylcimifugin | Prim-O-glucosylcimifugin exerts anti-inflammatory effects through the inhibition of iNOS and COX-2 expression by through regulating JAK2/STAT3 signaling. Uses: Scientific research. Group: Natural products. CAS No. 80681-45-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N0635. | |
| Pristane | Pristane (Norphytane) is a naturally occurring hydrocarbon oil found in small quantities in many plants, in various marine organisms, and as the most active component of mineral oil [1]. Pristane is a non-antigenic adjuvant, and induces MHC class II-restricted, arthritogenic T cells in the rat [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Norphytane. CAS No. 1921-70-6. Pack Sizes: 1 mL; 10 mM * 1 mL; 5 mL; 10 mL. Product ID: HY-N7819. | |
| Pristanic acid | Pristanic acid is an endogenous metabolite present in Blood that can be used for the research of Alpha Methylacyl CoA Racemase Deficiency and Zellweger Syndrome [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 1189-37-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-113024. | |
| Pristimerin | Pristimerin is a potent and reversible monoacylglycerol lipase ( MGL ) inhibitor with an IC 50 of 93 nM. Uses: Scientific research. Group: Natural products. Alternative Names: Celastrol methyl ester. CAS No. 1258-84-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N1937. | |
| Pristinamycin | Pristinamycin, produced by Streptomyces pristinaespiralis , is an orally active streptogramin-like antibiotic consisting of two chemically unrelated components: Pristinamycin I (PI) and Pristinamycin II (PII). Pristinamycin is highly active against many antibiotic-resistant pathogens, particularly Gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus (MRSA), Vancomycin-resistant S. aureus (VRSA) and Enterococcus faecium (VREF) [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Pristinamycine. CAS No. 270076-60-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-A0279. | |
| Pritelivir | Pritelivir (AIC316), an inhibitor of the viral helicase-primase complex , exhibits antiviral activity in vitro and in animal models of herpes simplex virus ( HSV ) infection. Pritelivir is active against herpes simplex virus types 1 and 2 ( HSV-1 and HSV-2 ) with the IC 50 of 0.02 μM against HSV1-2 [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AIC316; BAY 57-1293. CAS No. 348086-71-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15303. | |
| Pritelivir mesylate | Pritelivir mesylate (BAY 57-1293 mesylate), an inhibitor of the viral helicase-primase complex , exhibits antiviral activity in vitro and in animal models of herpes simplex virus ( HSV ) infection. Pritelivir mesylate is active against herpes simplex virus types 1 and 2 ( HSV-1 and HSV-2 ) with the IC 50 of 0.02 μM against HSV1-2 [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AIC316 mesylate; BAY 57-1293 mesylate. CAS No. 1428333-96-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15303A. | |
| Pritumumab | Pritumumab is a natural human IgG1kappa mAb originally isolated from a regional draining lymph node of a patient with cervical carcinoma. Pritumumab recognizes vimentin expressing on the cell surface of the malignant tumor. Pritumumab can be used for glioblastoma research [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 499212-74-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99806. | |
| PRLX-93936 dihydrochloride | PRLX-93936 dihydrochloride (Compound 16) is a HIF-1α inhibitor with anticancer activity. PRLX-93936 can inhibit the activated Ras pathway and can be used in the study of relapsed or refractory multiple myeloma [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1094210-96-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-119264A. | |
Would you like to list your products on USA Chemical Suppliers?
Our database is helping our users find suppliers everyday.