MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Ticlopidine hydrochloride | Ticlopidine hydrochloride is an adenosine diphosphate (ADP) receptor inhibitor against platelet aggregation with IC50 of ~2 μM. Uses: Scientific research. Group: Signaling pathways. CAS No. 53885-35-1. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-B0153A. |  |
| Tidiacic | Tidiacic is a hepatoprotective agent that acts as an antioxidant and a sulfur donor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 30097-06-4. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-W024241. | |
| Tienilic acid | Tienilic acid (Ticrynafen; ANP 3624) acts as a diuretic hypotensive agent. However, Tienilic acid induces hepatotoxicity. Tienilic acid is converted into electrophilic metabolites by cytochrome P450 (CYP) in vitro [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ticrynafen; ANP 3624. CAS No. 40180-04-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-21065. | |
| Tifcemalimab | Tifcemalimab (JS004) is a humanized anti- BTLA (B and T lymphocyte attenuation factor) monoclonal antibody. Tifcemalimab blocks the interaction of HVEM-BTLA by binding to BTLA, and thus blocks the inhibitory signaling pathway mediated by BTLA. Tifcemalimab can be used in research of cancer [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: JS004. CAS No. 2236068-83-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99961. | |
| Tigatuzumab | Tigatuzumab (CS-1008) is a humanized IgG1 monoclonal antibody targets death receptor 5 ( DR5 ). Tigatuzumab induces cell apoptosis of cancer cells and inhibits tumor growth in vivo. Tigatuzumab can be used for the research of cancer [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: CS-1008; Anti-Human TRAIL-R2 Recombinant Antibody. CAS No. 918127-53-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99270. | |
| Tigecycline | Tigecycline (GAR-936) is a broad-spectrum glycylcycline antibiotic. The mean inhibitory concentration (MIC) of Tigecycline for E. coli (MG1655 strain) is approximately 125 ng/mL [1]. MIC 50 and MIC 90 are 1 and 2 mg/L for Acinetobacter baumannii ( A. baumannii ), respectively [2]. Uses: Scientific research. Group: Natural products. Alternative Names: GAR-936. CAS No. 220620-09-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-B0117. | |
| Tigecycline hydrate | Tigecycline (GAR-936) hydrate is a broad-spectrum glycylcycline antibiotic. The mean inhibitory concentration (MIC) of Tigecycline hydrate for E. coli (MG1655 strain) is approximately 125 ng/mL [1]. MIC 50 and MIC 90 are 1 and 2 mg/L for Acinetobacter baumannii ( A. baumannii ), respectively [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GAR-936 hydrate. CAS No. 1229002-07-6. Pack Sizes: 1 mg. Product ID: HY-B0117D. | |
| Tigilanol tiglate | Tigilanol tiglate (EBC-46) is a protein kinase C ( PKC )/ C1 domain activator. Tigilanol tiglate is associated with mitochondrial/endoplasmic reticulum (ER) dysfunction, leading to activation of the unfolded protein response (UPRmt/ER) and subsequent induction of ATP depletion, organelles expansion, Caspase activation, gasdermin E cleavage, and terminal necrosis. Tigilanol tiglate, as a small anti-tumor molecule with immunomodulatory effects, can be used in the study of head and neck squamous cell carcinoma and soft tissue sarcoma [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EBC-46. CAS No. 943001-56-7. Pack Sizes: 1 mg. Product ID: HY-109076. | |
| Tiglic acid | Tiglic acid is a monocarboxylic unsaturated organic acid found in croton oil and in several other natural products. Tiglic aci has a role as a plant metabolite [1]. Uses: Scientific research. Group: Natural products. CAS No. 80-59-1. Pack Sizes: 10 mM * 1 mL; 100 mg; 1 g. Product ID: HY-W012999. | |
| Tigogenin | Tigogenin, one of steroidal sapogenins, is widely used for synthesizing steroid agents. Tigogenin inhibits adipocytic differentiation and induces osteoblastic differentiation in mouse bone marrow stromal cells [1]. Uses: Scientific research. Group: Natural products. CAS No. 77-60-1. Pack Sizes: 5 mg; 10 mg; 20 mg. Product ID: HY-N1403. | |
| Tigolaner | Tigolaner (BAY-1272858) acts on γ-aminobutyric acid ( GABA ) and glutamate-gated chloride channels. Tigolaner has antiparasitic activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY-1272858. CAS No. 1621436-41-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109077. | |
| Tigulixostat | Tigulixostat (LC350189) is an orally active, non-purine selective xanthine oxidase inhibitor. Tigulixostat lowers the production of uric acid. Tigulixostat can be used for gout and hyperuricemia study [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LC350189. CAS No. 1287766-55-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139585. | |
| Tilavonemab | Tilavonemab (ABBV-8E12) is a humanized anti- tau antibody that targets the extracellular form of pathological tau protein aggregates by binding to the N-terminal 25-30 amino acid residues of tau protein. Tilavonemab blocks the ability of human and mouse neurons to take up tau aggregates, reduces the loss of brain volume, slows the progression of tau pathology, and improves cognitive abilities in transgenic mice expressing mutant human tau. Tilavonemab is used in Alzheimer's disease research [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ABBV-8E12; C2N-8E12. CAS No. 2096513-89-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99163. | |
| Tildacerfont | Tildacerfont is a potent and orally active corticotrophin-releasing factor type 1 (CRF1) receptort antagonis. Tildacerfont effectively reduces adrenocorticotropic hormone (ACTH) and adrenal androgen levels. Tildacerfont has favourable safety profile. Tildacerfont can be used for researching congenital adrenal hyperplasia [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SPR001; LY2371712. CAS No. 1014983-00-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113603. | |
| Tildipirosin | Tildipirosin, a long-acting macrolide, has antibiotic activity. Uses: Scientific research. Group: Signaling pathways. CAS No. 328898-40-4. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-A0071. | |
| Tildrakizumab | Tildrakizumab (SCH 900222) is a humanized anti- IL-23 (p19 subunit) monoclonal antibody. IL-23 is a critical cytokine to maintain the Th17 cell phenotype. Tildrakizumab has high-affinity for single-chain IL-23 ( K d : 136 pM). Tildrakizumab is effective against moderate to severe plaque psoriasis [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: SCH 900222; MK 3222; Anti-Human IL23 Recombinant Antibody. CAS No. 1326244-10-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99256. | |
| Tiliroside | Tiliroside, a glycosidic flavonoid, possesses anti-diabetic activities. Tiliroside is a noncompetitive inhibitor of α-amylase with a K i value of 84.2 μM. Tiliroside inhibits carbohydrate digestion and glucose absorption in the gastrointestinal tract [1]. Uses: Scientific research. Group: Natural products. CAS No. 20316-62-5. Pack Sizes: 5 mg; 10 mg; 20 mg. Product ID: HY-N1425. | |
| Tilmicosin | Tilmicosin (LY-177370) is an orally active calcium channel antagonist and macrolide antibiotic with antimicrobial activity. Tilmicosin mainly acts on the 50S subunit of bacterial ribosomes, inhibiting protein synthesis. Tilmicosin is effective in the treatment of respiratory diseases in livestock such as cattle, sheep and pigs. In addition, Tilmicosin has immunomodulatory and anti-inflammatory effects [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY-177370; EL-870. CAS No. 108050-54-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0905. | |
| Tilmicosin phosphate | Tilmicosin (LY-177370) phosphate is an orally active calcium channel antagonist and macrolide antibiotic with antimicrobial activity. Tilmicosin phosphate mainly acts on the 50S subunit of bacterial ribosomes, inhibiting protein synthesis. Tilmicosin phosphate is effective in the treatment of respiratory diseases in livestock such as cattle, sheep and pigs. In addition, Tilmicosin phosphate has immunomodulatory and anti-inflammatory effects [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY-177370 phosphate; EL-870 phosphate. CAS No. 137330-13-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0905A. | |
| Tilorone | Tilorone is an orally active antiviral agent and interferon inducer that also has potential antineoplastic, immunomodulatory, and metabolic modulating effects. Tilorone induces an abnormally delayed interferon response and primarily stimulates interferon production in lymphoid tissue. Thus, Tilorone exerts antiviral effects and can be used as a chemotherapeutic agent. Tilorone has the potential to inhibit type 2 diabetes by increasing glucose uptake in vivo and in skeletal muscle cells by enhancing Akt2/AS160 signaling and glucose transporter levels [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 27591-97-5. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1080A. | |
| Tilorone dihydrochloride | Tilorone dihydrochloride is an orally active interferon (IFN) inducer with broad-spectrum antiviral activities. Tilorone dihydrochloride possesses robust anti-Severe fever with thrombocytopenia syndrome virus (SFTSV) activity in vitro and in vivo through stimulation of host innate immunity. Tilorone dihydrochloride can penetrate the blood-brain barrier to activate HIF in the CNS [1] [2] [3].Tilorone dihydrochloride exhibits an inhibitory activity with EC 50 of 230 nM against Ebola virus (EBOV) [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 27591-69-1. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B1080. | |
| Tiludronate disodium | Tiludronate (Tiludronic Acid) disodium, an orally active bisphosphonate, can act an osteoregulator. Tiludronate is used for the research of the metabolic bone disorders. Tiludronate is a potent inhibitor of the osteoclast vacuolar H(+)-ATPase. Antiresorptive and anti-inflammatory properties [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Tiludronic acid disodium. CAS No. 149845-07-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-A0213A. | |
| Timonacic | Timonacic (1,3-Thiazolidine-4-carboxylic acid) is a thiol antioxidant. Timonacic has anti-aging and anti-hepatotoxic effects, and it can be used to study acute illnesses and liver diseases, by inducing reversal, it is also used in research on certain cancer cases [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 1,3-Thiazolidine-4-carboxylic acid. CAS No. 444-27-9. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-B1169. | |
| Timosaponin AIII | Timosaponin AIII could inhibit acetylcholinesterase (AChE) activity, with an IC 50 of 35.4 μM. Uses: Scientific research. Group: Natural products. CAS No. 41059-79-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N0810. | |
| Tinengotinib | Tinengotinib is the modulator of one or more protein kinases such as Aurora kinase and VEGFR kinase. Tinengotinib has the potential for the research of these kinase abnormalities diseases mediated, especially cancer-related diseases (extracted from patent WO2018108079A1) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TT 00420. CAS No. 2230490-29-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145601. | |
| Tinidazole | Tinidazole, an orally available antibacterial agent, is a 5-nitroimidazole with selective activity against anaerobic bacteria and protozoa [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 19387-91-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 1 g; 5 g. Product ID: HY-B0177. | |
| Tinidazole (Standard) | Tinidazole (Standard) is the analytical standard of Tinidazole. This product is intended for research and analytical applications. Tinidazole, an orally available antibacterial agent, is a 5-nitroimidazole with selective activity against anaerobic bacteria and protozoa [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 19387-91-8. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-B0177R. | |
| Tin(II) chloride dihydrate | Tin(II) chloride dihydrate (Tinchloridedihydrate) is a kind of biological materials or organic compounds that are widely used in life science research [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Tinchloridedihydrate. CAS No. 10025-69-1. Pack Sizes: 25 g; 100 g. Product ID: HY-Y0481A. | |
| Tin(II) oxalate | Tin(II) oxalate (Stannous oxalate) is a kind of biological materials or organic compounds that are widely used in life science research [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Stannous oxalate. CAS No. 814-94-8. Pack Sizes: 10 g. Product ID: HY-W105856. | |
| Tinoridine | Tinoridine (Y-3642) is an orally active non-steroidal anti-inflammatory agent with potent antiperoxidative ability and radical scavenger activity. Tinoridine acts function by inhibiting COX enzyme, involves in hepatotoxicity inhibition. [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Y-3642. CAS No. 24237-54-5. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W032848. | |
| Tinoridine hydrochloride | Tinoridine hydrochloride is a nonsteroidal anti-inflammatory agent and also has potent radical scavenger and antiperoxidative activity. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Y-3642 hydrochloride. CAS No. 25913-34-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111354. | |
| Tinostamustine | Tinostamustine (EDO-S101) is a pan HDAC inhibitor; inhibits HDAC6 , HDAC1 , HDAC2 and HDAC3 with IC 50 values of 6 nM, 9 nM, 9 nM and 25 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EDO-S101; NL-101. CAS No. 1236199-60-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101780. | |
| Tin protoporphyrin IX dichloride | Tin protoporphyrin IX dichloride (SnPPIX) is a potent Heme oxygenase-1 (HO-1) inhibitor. Tin protoporphyrin IX dichloride sensitizes pancreatic ductal adenocarcinoma (PDAC) tumors to chemotherapy in mice model [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Tin-protoporphyrin IX; Sn-Protoporphyrin; SnPPIX. CAS No. 14325-05-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-101194. | |
| Tioconazole | Tioconazole (UK-20349) is a broad-spectrum antifungal imidazole derivative. Tioconazole inhibits several dermatophytes and yeasts, with MIC 50 values of less than 3.12 mg/L and 9 mg/L, respectively. Additionally, Tioconazole exhibits anti-parasitic activity. Tioconazole exerts anticancer activity by inhibiting the PI3K/AKT/mTOR signaling pathway and blocking autophagy. Tioconazole is applicable for research in the fields of anti-infection and anticancer therapy [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: UK-20349. CAS No. 65899-73-2. Pack Sizes: 10 mM * 1 mL; 500 mg; 5 g; 10 g. Product ID: HY-B0319. | |
| Tiopronin | Tiopronin is a diffusible antioxidant, an antidote to heavy metal poisoning and a radioprotective agent. Tiopronin can control the rate of cystine precipitation and excretion and has the potential for cystinuria, rheumatoid arthritis and hepatic disorders [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 1953-2-2. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-B0373. | |
| Tiopronin-cysteine disulfide | Tiopronin-cysteine disulfide is a disulfide formed by Tiopronin (HY-B0373) and cysteine [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 77591-18-5. Pack Sizes: 1 mg. Product ID: HY-131516. | |
| Tiotropium Bromide | Tiotropium Bromide (BA679 BR) is a muscarinic acetylcholine receptor (mAChR) antagonist that blocks the binding of the acetylcholine ligand and subsequent opening of the ligand-gated ion channel. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BA679 BR. CAS No. 136310-93-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-17360. | |
| Tiotropium bromide monohydrate | Tiotropium bromide (BA-679 BR) monohydrate is a long-acting muscarinic receptor antagonist [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BA-679 BR monohydrate. CAS No. 411207-31-3. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B0460. | |
| Tioxolone | Tioxolone is an inhibitor of the metalloenzyme carbonic anhydrase I and has anti-acne activity. Uses: Scientific research. Group: Signaling pathways. CAS No. 4991-65-5. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-B0483. | |
| Tipelukast | Tipelukast (KCA 757) is a sulfidopeptide leukotriene receptor antagonist, an orally bioavailable anti-inflammatory agent and used for the treatment of asthma. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KCA 757; MN 001. CAS No. 125961-82-2. Pack Sizes: 1 mg. Product ID: HY-14938. | |
| Tipepidine hydrochloride | Tipepidine hydrochloride reversibly inhibits dopamine (DA) D 2 receptor-mediated GIRK currents (I DA(GIRK) ) with an IC 50 of 7.0 μM. Tipepidine hydrochloride subsequently activates VTA dopamine neuron [1]. Tipepidine hydrochloride, a non-narcotic antitussive, exerts an antidepressant-like effect [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1449686-84-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-121685A. | |
| Tipifarnib | Tipifarnib (IND 58359) binds to and inhibits farnesyltransferase (FTase) with an IC 50 of 0.86 nM. Antineoplastic activity and antiparasitic activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IND 58359; R115777. CAS No. 192185-72-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10502. | |
| Tipiracil | Tipiracil is a thymidine phosphorylase ( TPase ) inhibitor. Uses: Scientific research. Group: Signaling pathways. CAS No. 183204-74-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-A0063A. | |
| Tipiracil hydrochloride | Tipiracil (hydrochloride) is a thymidine phosphorylase inhibitor (TPI), used for cancer research. Uses: Scientific research. Group: Signaling pathways. CAS No. 183204-72-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-A0063. | |
| Tipranavir | Tipranavir (PNU-140690) inhibits the enzymatic activity and dimerization of HIV-1 protease , exerts potent activity against multi-protease inhibitor (PI)-resistant HIV-1 isolates with IC 50 s of 66-410 nM [1] [2]. Tipranavir inhibits SARS-CoV-2 3CL pro activity [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PNU-140690. CAS No. 174484-41-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-15148. | |
| Tirabrutinib | Tirabrutinib (ONO-4059) is an orally active Brutons Tyrosine Kinase ( BTK ) inhibitor (can cross the blood-brain barrier (BBB)), with an IC 50 of 6.8 nM. Tirabrutinib irreversibly and covalently binds to BTK and inhibits aberrant B cell receptor signaling. Tirabrutinib can be used in studies of autoimmune diseases and hematological malignancies [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ONO-4059; GS-4059. CAS No. 1351636-18-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15771. | |
| Tirabrutinib hydrochloride | Tirabrutinib (ONO-4059) hydrochloride is an orally active Brutons Tyrosine Kinase ( BTK ) inhibitor (can cross the blood-brain barrier (BBB)), with an IC 50 of 6.8 nM. Tirabrutinib hydrochloride irreversibly and covalently binds to BTK and inhibits aberrant B cell receptor signaling. Tirabrutinib hydrochloride can be used in studies of autoimmune diseases and hematological malignancies [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ONO-4059 hydrochloride; GS-4059 hydrochloride. CAS No. 1439901-97-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15771A. | |
| Tiragolumab | Tiragolumab is an immune checkpoint inhibitor binding to T-cell immunoglobulin and ITIM domain ( TIGIT ). Tiragolumab, alone or in combination with the PD-L1 inhibitor Atezolizumab (HY-P9904), may be effective against multiple solid malignancies-most notably non-small cell lung cancer (NSCLC) [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MTIG-7192A; RG-6058. CAS No. 1918185-84-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9986. | |
| Tirapazamine | Tirapazamine (SR259075) is an anticancer agent that shows selective cytotoxicity for hypoxic cells in solid tumors, thereby inducing single-and double-strand breaks in DNA, base damage, and cell death. Tirapazamine is an anticancer and bioreductive agent.Tirapazamine (SR259075) can enhance the cytotoxic effects of ionizing radiation in hypoxic cells [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SR259075; SR4233; Win59075; SML 0552; SR 259075; Tirazone. CAS No. 27314-97-2. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg. Product ID: HY-13767. | |
| Tirasemtiv | Tirasemtiv is an activator of the fast skeletal muscle troponin complex. Tirasemtiv is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CK-2017357. CAS No. 1005491-05-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15964. | |
| Tiratricol | Tiratricol is an orally available thyroid hormone analog that inhibits pituitary thyroid-stimulating hormone secretion. Tiratricol is an intracellular toxin neutralizer that inhibits LPS and lipid A cytotoxicity with IC 50 s of 20 μM and 32 μM, respectively. Tiratricol reduces TNF production in lipopolysaccharide-stimulated macrophages. Tiratricol also has antiviral activity and is an inhibitor of yellow fever virus (Flavivirus). It can bind to the RdRp domain of the viral NS5 protein to hinder YFV replication. [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 3,3',5-Triiodothyroacetic acid. CAS No. 51-24-1. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B1201. | |
| Tirbanibulin | Tirbanibulin (KX2-391) is an inhibitor of Src that targets the peptide substrate site of Src, with GI 50 of 9-60 nM in cancer cell lines. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KX2-391; KX-01. CAS No. 897016-82-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10340. | |
| Tirbanibulin dihydrochloride | Tirbanibulin (dihydrochloride) (KX2-391 (dihydrochloride)) is an inhibitor of Src that targets the peptide substrate site of Src, with GI 50 of 9-60 nM in cancer cell lines. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KX2-391 dihydrochloride; KX-01 dihydrochloride. CAS No. 1038395-65-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10340A. | |
| Tirbanibulin Mesylate | Tirbanibulin Mesylate (KX2-391 Mesylate) is an inhibitor of Src that targets the peptide substrate site of Src, with GI 50 of 9-60 nM in cancer cell lines. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KX2-391 Mesylate; KX01 Mesylate. CAS No. 1080645-95-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10340B. | |
| Tirilazad | Tirilazad is a nonglucocorticoid, 21-aminosteroid that inhibits lipid peroxidation. Tirilazad can attenuate brain or spinal cord injury caused by trauma, stroke, ischemia and reperfusion injury. Tirilazad has antiviral activities against nCoV. Tirilazad is neuroprotective for ischaemic stroke, can be used for subarachnoid hemorrhage research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: U 74006F free base. CAS No. 110101-66-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-132280. | |
| Tirnovetmab | Tirnovetmab (KIND-016) is an antibody. Tirnovetmab can be used for experiment research. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: KIND-016. CAS No. 2364504-80-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99557. | |
| Tirofiban | Tirofiban (L700462) is a selective and reversible platelet integrin receptor ( Gp IIb/IIIa ) antagonist that inhibits fibrinogen binding to this receptor and has antithrombotic activity. Tirofiban induces proliferation and migration on endothelial cell by inducing production of VEGF. Tirofiban can significantly reduces myocardial no-reflow and ischemia-reperfusion injury by alleviating myocardial microvascular structural and endothelial dysfunction in the ischemic area [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: L700462; MK383. CAS No. 144494-65-5. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17369B. | |
| Tirofiban hydrochloride monohydrate | Tirofiban (L700462) hydrochloride monohydrate is a selective and reversible platelet integrin receptor ( Gp IIb/IIIa ) antagonist that inhibits fibrinogen binding to this receptor and has antithrombotic activity. Tirofiban hydrochloride monohydrate induces proliferation and migration on endothelial cell by inducing production of VEGF. Tirofiban hydrochloride monohydrate can significantly reduces myocardial no-reflow and ischemia-reperfusion injury by alleviating myocardial microvascular structural and endothelial dysfunction in the ischemic area [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: L700462 hydrochloride monohydrate; MK383 hydrochloride monohydrate. CAS No. 150915-40-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17369. | |
| Tiron | Tiron is a non-toxic chelator of a variety of metals. Tiron is cell permeable analog of vitamin E and function as hydroxyl radical and superoxide scavenger. Tiron is an orally active antioxidant. Tiron can be used to alleviate acute metal overload in animals [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 149-45-1. Pack Sizes: 10 mM * 1 mL; 10 g; 25 g. Product ID: HY-D0261. | |
| Tislelizumab | Tislelizumab is a monoclonal antibody that specifically binds to programmed cell death receptor 1 (PD-1), blocking its interaction with programmed death ligand 1 (PD-L1) and programmed death ligand 2 (PD-L2). Tislelizumab can reactivate immune cells such as T lymphocytes and enhance anti-tumor activity. Tislelizumab can be used for the research of a variety of tumors including typical Hodgkin's lymphoma, urothelial carcinoma, non-small cell lung cancer and hepatocellular carcinoma [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1858168-59-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99052. | |
| Tisolagiline | Tisolagiline (KDS2010) is a reversible MAO-B inhibitor used in Parkinson's disease research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KDS2010. CAS No. 1894207-44-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-127109. | |
| Tisotumab | Tisotumab (Anti-Human F3 Recombinant Antibody) is a human IgG1 monoclonal antibody and ADC antibody. Tisotumab targets tissue factor ( TF ). Tisotumab can be used for the research of solid tumors [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-Human F3 Recombinant Antibody. CAS No. 1418628-81-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99271. | |
| Tisotumab vedotin | Tisotumab vedotin is an antibody drug conjugate (ADC) targeting tissue factor (TF), formed by covalently linking a fully human monoclonal antibody (TF-011) against TF with the microtubule disruptor Monomethyll Auristatin E (MMAE) (HY-15162). Tisotumab vedotin has immunomodulatory and anti-tumor activities, and can be used in the study of advanced or metastatic solid tumors such as cervical cancer [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1418731-10-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-152963. | |
| Tivantinib | Tivantinib is a highly selective c-Met tyrosine kinase inhibitor with a K i of 355 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ARQ 197; (3R,4R)-ARQ 198. CAS No. 905854-02-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-50686. | |
| Tivozanib | Tivozanib (AV-951; KRN951) is a selective, orally active inhibitor for vascular endothelial growth factor receptor ( VEGFR )-1, 2 3, with IC 50 s of 30, 6.5 and 15 nM, respectively. Tivozanib exhibits antitumor efficacy [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AV-951; KRN951. CAS No. 475108-18-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10977. | |
| Tivozanib hydrate | Tivozanib hydrate (AV-951 hydrate; KRN951 hydrate) is the hydrate form of Tivozanib (HY-10977). Tivozanib hydrate is a selective, orally active inhibitor for vascular endothelial growth factor receptor ( VEGFR )-1, 2 3, with IC 50 s of 30, 6.5 and 15 nM, respectively. Tivozanib hydrate exhibits antitumor efficacy [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AV-951 hydrate; KRN951 hydrate. CAS No. 682745-40-0. Pack Sizes: 1 mg. Product ID: HY-112467. | |
| Tivozanib hydrochloride hydrate | Tivozanib hydrochloride hydrate is the hydrate hydrochloride form of Tivozanib (HY-10977). Tivozanib hydrochloride hydrate is a selective, orally active inhibitor for vascular endothelial growth factor receptor ( VEGFR )-1, 2 3, with IC 50 s of 30, 6.5 and 15 nM, respectively. Tivozanib hydrochloride hydrate exhibits antitumor efficacy [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AV-951 hydrochloride hydrate; KRN951 hydrochloride hydrate. CAS No. 682745-41-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10977A. | |
| Tivumecirnon | Tivumecirnon (FLX475) is an orally active, selective CCR4 antagonist. Tivumecirnon blocks the binding of CCR4 to its ligands, CCL17 and CCL22 , thereby reducing Treg infiltration into the tumor microenvironment. Tivumecirnon has antitumor activity [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FLX475. CAS No. 2174938-78-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148494. | |
| Tixagevimab | Tixagevimab (AZD8895) is a human monoclonal antibody that targets the SARS-CoV-2 receptor binding domain (RBD). It exhibits neutralizing activity against SARS-CoV-2 by binding to the RBD and the S-glycoprotein ectodomain and blocking S-glycoprotein-mediated binding to the receptor [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: AZD8895. CAS No. 2420564-02-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99556. | |
| Tizanidine | Tizanidine is an α2-adrenergic receptor agonist and inhibits neurotransmitter release from CNS noradrenergic neurons. Uses: Scientific research. Group: Signaling pathways. CAS No. 51322-75-9. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0194. | |
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