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Pictilisib dimethanesulfonate
Pictilisib dimethanesulfonate (GDC-0941 dimethanesulfonate) is a potent inhibitor of PI3Kα/δ with IC 50 of 3 nM, with modest selectivity against p110β (11-fold) and p110γ (25-fold). Uses: Scientific research. Group: Signaling pathways. Alternative Names: GDC-0941 dimethanesulfonate; GDC-0941 2 MeSO3H salt. CAS No. 957054-33-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-20180.
Pidotimod
Pidotimod is an orally active dipeptide immunostimulant with immunomodulatory properties on the adaptive and the innate immune responses. Pidotimod increases macrophage activity and humoral immune functions. Pidotimod can be used for the research of chronic bronchitis, chronic obstructive pulmonary disease (COPD), bronchiectasis, and chronic idiopathic urticaria,et al [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 121808-62-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0944.
Piericidin A
Piericidin A (AR-054) is a natural mitochondrial NADH-ubiquinone oxidoreductase (complex I) inhibitor. Piericidin A is a potent neurotoxin and inhibits mitochondrial respiration by disrupting the electron transport system through its action on NADH-ubiquinone reductase. Piericidin A is also a potential quorum-sensing inhibitor that suppresses the expression of the virulence genes of Erwinia carotovora subsp. atroseptica (Eca). Piericidin A is an ADC cytotoxin and has anti-bacterial, anticancer, insecticidal activity[1][2][2]. Uses: Scientific research. Group: Natural products. Alternative Names: AR-054. CAS No. 2738-64-9. Pack Sizes: 1 mg (12.03 mM * 200 ?L in Ethanol). Product ID: HY-114936.
Pifithrin-α hydrobromide
Pifithrin-α hydrobromide is a p53 inhibitor which blocks its transcriptional activity and prevents cells from apoptosis. Pifithrin-α hydrobromide is also an aryl hydrocarbon receptor (AhR) agonist. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Pifithrin hydrobromide; PFTα hydrobromide. CAS No. 63208-82-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15484.
Pifithrin-β hydrobromide
Pifithrin-β hydrobromide (PFT β hydrobromide) is a potent p53 inhibitor with an IC 50 of 23 μM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PFT β hydrobromide; Cyclic Pifithrin-α hydrobromide. CAS No. 511296-88-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16702A.
Piflufolastat
Piflufolastat (DCFPYL) can be used to the preparation of piflufolastat F 18 (DCFPyL F-18). piflufolastat F 18. Piflufolastat F-18 is an 18F-labelled diagnostic imaging agent. Piflufolastat F-18 can be used for positron emission tomography (PET) that targets prostate-specific membrane antigen (PSMA) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DCFPYL. CAS No. 1423758-00-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117756.
Pifusertib hydrochloride
Pifusertib (TAS-117) hydrochloride is a potent, selective, orally active allosteric Akt inhibitor (with IC 50 s of 4.8, 1.6, and 44 nM for Akt1, 2, and 3, respectively). Pifusertib hydrochloride triggers anti-myeloma activities and enhances fatal endoplasmic reticulum (ER) stress induced by proteasome inhibition. Pifusertib hydrochloride induces apoptosis and autophagy [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TAS-117 hydrochloride. CAS No. 2930090-28-9. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-19934A.
Pigment red 170
Pigment Red 170 is a commonly used commercial dye for bulk coloring of plastics and synthetic fibers and for surface coatings such as paints and inks. Uses: Scientific research. Group: Fluorescent dye. CAS No. 2786-76-7. Pack Sizes: 500 mg; 1 g. Product ID: HY-D0278.
Pigment Yellow 14
Pigment Yellow 14 is a fluorescent dye [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 5468-75-7. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-D0281.
Pigment Yellow 83
Pigment Yellow 83 is a yellow colorant [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 5567-15-7. Pack Sizes: 500 mg; 1 g. Product ID: HY-D0283.
PIK-75
PIK-75 is a reversible DNA-PK and p110α -selective inhibitor, which inhibits DNA-PK, p110α and p110γ with IC 50 s of 2, 5.8 and 76 nM, respectively. PIK-75 inhibits p110α >200-fold more potently than p110β (IC 50 =1.3 μM) [1] [2]. PIK-75 induces apoptosis [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 372196-67-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107834.
PIK-75 hydrochloride
PIK-75 hydrochloride is a reversible DNA-PK and p110α -selective inhibitor, which inhibits DNA-PK, p110α and p110γ with IC 50 s of 2, 5.8 and 76 nM, respectively. PIK-75 hydrochloride inhibits p110α >200-fold more potently than p110β (IC 50 =1.3 μM) [1] [2]. PIK-75 hydrochloride induces apoptosis [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 372196-77-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13281.
PIK-90
PIK-90 is a DNA-PK and PI3K inhibitor, which inhibits p110?, p110? and DNA-PK with IC50s of 11, 18 and 13 nM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 677338-12-4. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12030.
PIK-93
PIK-93 is the first potent, synthetic PI4K (PI4KIII?) inhibitor with IC50 of 19 nM, and also inhibits PI3K? and PI3K? with IC50 of 16 nM and 39 nM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 593960-11-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12046.
Piketoprofen
Piketoprofen is a non-steroidal anti-inflammatory reagent that can be used as a cream preparation for the study of soft tissue rheumatism. Piketoprofen-amide is a prodrug of COX-2 inhibitor [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 60576-13-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108297.
PIKfyve-IN-1
PIKfyve-IN-1 is a highly potent and cell-active chemical probe that inhibits phosphatidylinositol-3phosphate 5-kinase (PIKfyve) with IC50 value of 6.9 nM. PIKfyve-IN-1 can be used for the research of PIKfyve in virology[1]. PIKfyve-IN-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 2857982-26-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-151473.
Pilaralisib
Pilaralisib (XL147; SAR245408) is a potent and highly selective class I PI3K s inhibitor with IC 50 s of 39 nM, 383 nM, 23 nM and 36 nM for PI3Kα, PI3Kβ, PI3Kγ, and PI3K&delta. Uses: Scientific research. Group: Signaling pathways. Alternative Names: XL-147; SAR245408. CAS No. 934526-89-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16526.
Pilocarpine
Pilocarpine is a selective M3-type muscarinic acetylcholine receptor ( M3 muscarinic receptor ) agonist. Uses: Scientific research. Group: Signaling pathways. CAS No. 92-13-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-B0726A.
Pilocarpine Hydrochloride
Pilocarpine Hydrochloride is a potent M3-type muscarinic acetylcholine receptor ( M3 muscarinic receptor ) agonist. Uses: Scientific research. Group: Natural products. CAS No. 54-71-7. Pack Sizes: 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B0726.
Pilsicainide hydrochloride (SUN-1165) is an orally active sodium channel blocker and potent class Ic antiarrhythmic agent [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: SUN-1165; Pilzicainide(hydrochloride). CAS No. 88069-49-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-101245.
Pim1/AKK1-IN-1
Pim1/AKK1-IN-1 is a potent multi-kinase inhibitor with Kd values of 35 nM/53 nM/75 nM/380 nM for Pim1/AKK1/MST2/LKB1 respectively, and also inhibits MPSK1 and TNIK. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LKB1/AAK1 dual inhibitor. CAS No. 1093222-27-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-10371.
PIM1-IN-1
PIM1-IN-1 is a potent and highly selective PIM1/3 inhibitor, with IC 50 s of 7, 5530 and 70 nM for PIM1, PIM2, and PIM3, respectively, inhibits the phosphorylation of BAD, a downstream target of PIM, with an EC 50 of 262 nM. PIM1-IN-1 shows no obvious effect on FLT3 or hERG binding. Antiproliferative and anti-cancer activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1417630-95-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111552.
PIM447
PIM447 (LGH447) is a potent, orally available, and selective pan- PIM kinase inhibitor, with K i values of 6, 18, and 9 pM for PIM1, PIM2, and PIM3, respectively. PIM447 displays dual antimyeloma and bone-protective effects. PIM447 induces apoptosis [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LGH447. CAS No. 1210608-43-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-19322.
PIM-447 dihydrochloride
PIM447 dihydrochloride (LGH447 dihydrochloride) is a potent, orally available, and selective pan- PIM kinase inhibitor, with K i values of 6, 18, and 9 pM for PIM1, PIM2, and PIM3, respectively. PIM447 dihydrochloride displays dual antimyeloma and bone-protective effects. PIM447 dihydrochloride induces apoptosis [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LGH447 dihydrochloride. CAS No. 1820565-69-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-19322B.
Pimasertib
Pimasertib (AS703026) is a highly selective, ATP non-competitive allosteric orally available MEK1/2 inhibitor [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AS703026; MSC1936369B. CAS No. 1236699-92-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12042.
Pimavanserin
Pimavanserin is a selective inverse agonist of the 5-HT2A receptor with pIC 50 and pK d of 8.73 and 9.3, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ACP-103. CAS No. 706779-91-1. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14557.
Pimavanserin hemitartrate
Pimavanserin (ACP-103) hemitartrate is a potent 5-HT 2A receptor inverse agonist with pIC 50 and pK i of 8.73 and 9.3, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ACP-103 hemitartrate. CAS No. 706782-28-7. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14557A.
Pimecrolimus
Pimecrolimus (SDZ-ASM 981) is a potent, nonsteroid and orally active calcineurin inhibitor with a K i of 117 nM. Pimecrolimus shows anti-inflammatory activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SDZ-ASM 981. CAS No. 137071-32-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-13723.
Pimelic acid
Pimelic acid is the organic compound and its derivatives are involved in the biosynthesis of the amino acid called lysine.Pimelic acid can be used in keratoconus research [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Heptanedioic acid; 1,5-Pentanedicarboxylic acid; 1,7-Heptanedioic acid. CAS No. 111-16-0. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-Y1139.
Pimeloyl-CoA
Pimeloyl-CoA is a biotin precursor of Escherichia coli. Pimeloyl-CoA can be used for the research of the pathway of de novo biotin biosynthesis in Escherichia coli [1]. Uses: Scientific research. Group: Natural products. CAS No. 18907-20-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-142080.
Pimethixene maleate
Pimethixene maleate is antihistamine and antiserotonergic compound, acts as an antimigraine agent. Pimethixene maleate is a highly potent antagonist of 5-HT 1A , 5-HT 2A , 5-HT 2B , 5-HT 2C , histamine H 1 , dopamine D 2 and D 4.4 as well as muscarinic M 1 and M 2 receptors, with pK i s of 7.63, 10.22, 10.44, 8.42, 10.14, 8.19, 7.54, 8.61 and 9.38, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Pimetixene maleate. CAS No. 13187-06-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-B1101A.
Pimicotinib
Pimicotinib is a CSF1R inhibitor with antitumor activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABSK021. CAS No. 2253123-16-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153920.
Pimitespib
Pimitespib (TAS-116) is an oral bioavailable, ATP-competitive, highly specific HSP90α/HSP90β inhibitor ( K i s of 34.7 nM and 21.3 nM, respectively) without inhibiting other HSP90 family proteins such as GRP94 [1]. Pimitespib demonstrates less ocular toxicity [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TAS-116. CAS No. 1260533-36-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15785.
Pimobendan
Pimobendan (UD-CG115) is a selective inhibitor of PDE3 with IC 50 of 0.32 μM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: UD-CG115. CAS No. 74150-27-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-B0204.
Pimodivir
Pimodivir (VX-787) is an orally bioavailable inhibitor of influenza A virus polymerases through interaction with the viral PB2 subunit. Uses: Scientific research. Group: Signaling pathways. Alternative Names: VX-787. CAS No. 1629869-44-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12353A.
Pimonidazole
Pimonidazole is a novel hypoxia marker for complementary study of tumor hypoxia and cell proliferation in tumor [1]. Pimonidazole accumulates in hypoxic cells via covalent binding with macromolecules or by forming reductive metabolites after reduction of its nitro group, it can be used for qualitative and quantitative assessment of tumor hypoxia [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 70132-50-2. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-105129A.
Pimonidazole hydrochloride
Pimonidazole is a novel hypoxia marker for complementary study of tumor hypoxia and cell proliferation in tumor [1]. Pimonidazole accumulates in hypoxic cells via covalent binding with macromolecules or by forming reductive metabolites after reduction of its nitro group, it can be used for qualitative and quantitative assessment of tumor hypoxia [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 70132-51-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-105129.
Pimozide
Pimozide is a dopamine receptor antagonist, with K i s of 1.4 nM, 2.5 nM and 588 nM for dopamine D2, D3 and D1 receptors, respectively, and also has affinity at α1-adrenoceptor , with a K i of 39 nM; Pimozide also inhibits STAT3 and STAT5. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R6238. CAS No. 2062-78-4. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-12987.
Pinacidil
Pinacidil is a potent activator of potassium channel. Pinacidil is an antihypertensive agent which hyperpolarises vascular smooth muscle by opening K + -channels. Pinacidil significantly improves the reperfusion function and cardiac compliance. Pinacidil has direct cardioprotective efficacy [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: P-1134. CAS No. 60560-33-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14290.
Pinacidil monohydrate
Pinacidil (P-1134) monohydrate, an antihypertensive agent, is a potassium channel activator. Uses: Scientific research. Group: Natural products. Alternative Names: P-1134 monohydrate. CAS No. 85371-64-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14290A.
Pinaverium bromide
Pinaverium bromide is an L-type calcium channel blocker with selectivity for the gastrointestinal tract, effectively relieves pain, diarrhea and intestinal discomfort, provides good therapeutic efficacies without significant adverse effects on Irritable bowel syndrome (IBS) patients [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 53251-94-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111613.
Pindolol
Pindolol (LB-46) is a nonselective β-blocker with partial beta-adrenergic receptor agonist activity, also functions as a 5-HT1A receptor weak partial antagonist (Ki=33nM). Uses: Scientific research. Group: Signaling pathways. Alternative Names: LB-46. CAS No. 13523-86-9. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B0982.
Pinealon
Pinealon is a 3-amino acid peptide and shows neuroprotective properties. Pinealon prevents reactive oxygen species (ROS) accumulation and suppresses the activation of ERK 1/2. Pinealon stimulates the functional activity of the main cellular elements of brain tissue, reduces the level of spontaneous cell death. Pinealon protects the rat offspring from prenatal hyperhomocysteinemia [1] [2] [3]. Uses: Scientific research. Group: Peptides. CAS No. 175175-23-2. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-P4052.
Pinobanksin
Pinobanksin has apoptotic induction in a B-cell lymphoma cell line [1]. Uses: Scientific research. Group: Natural products. Alternative Names: 3,5,7-Trihydroxyflavanone. CAS No. 548-82-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N3062.
Pinocembrin
Pinocembrin ((+)-Pinocoembrin) is a flavonoid found in propolis, acts as a competitive inhibitor of histidine decarboxylase , and is an effective anti-allergic agent, with antioxidant, antimicrobial and anti-inflammatory properties [1]. Uses: Scientific research. Group: Natural products. Alternative Names: (+)-Pinocoembrin; Dihydrochrysin; Galangin flavanone. CAS No. 480-39-7. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg. Product ID: HY-N0575.
(±)-Pinocembrin
(±)-Pinocembrin ((±)-5,7-Dihydroxyflavanone) is a GPR120 ligand able to promote wound healing in HaCaT cell line [1]. Uses: Scientific research. Group: Natural products. Alternative Names: (±)-5,7-Dihydroxyflavanone; NSC 43318. CAS No. 68745-38-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N2540.
Pinolenic acid
Pinolenic acid (PNLA) is a polyunsaturated fatty acid that can be isolated from Pinus orientalis and Pinus pinaster seed oil. Pinolenic acid has anti-inflammatory and lipid-lowering activities [1]. Uses: Scientific research. Group: Natural products. Alternative Names: PNLA. CAS No. 16833-54-8. Pack Sizes: 5 mg (35.92 mM * 500μL in Ethanol); 10 mg (35.92 mM * 1mL in Ethanol). Product ID: HY-119546.
Pinometostat
Pinometostat (EPZ-5676) is a potent DOT1L histone methyltransferase inhibitor with a K i of 80 pM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EPZ-5676. CAS No. 1380288-87-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15593.
Pinoresinol
Pinoresinol is a lignol of plant origin serving for defense in a caterpillar. Pinoresinol drastically sensitizes cancer cells against TNF-related apoptosis-inducing ligand (TRAIL) -induced apoptosis [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: (+)-Pinoresinol. CAS No. 487-36-5. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-N6253.
Pinoresinol Diglucoside
Pinoresinol Diglucoside is one of the major lignans with various pharmacological activities which could be isolated from Duzhong and other plant species. Uses: Scientific research. Group: Natural products. CAS No. 63902-38-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0657.
Pinostrobin
Pinostrobin is a flavonoid with anti-cancer, antioxidant, antiviral and neuroprotective activities. Pinostrobin has oral activity. Pinostrobin is a potent PCSK9 inhibitor that inhibits the catalytic activity of PCSK9. Pinostrobin can be used in the research of viral infections, cancer, leukemia, cardiovascular and cerebrovascular diseases, cirrhosis, inflammation and neurological diseases [1] [2] [3] [4] [5] [6] [7] [8]. Uses: Scientific research. Group: Natural products. CAS No. 480-37-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N2127.
Pinosylvin
Pinosylvin is a pre-infectious stilbenoid toxin isolated from the heartwood of Pinus species, has anti-bacterial activities [1]. Pinosylvin is a resveratrol analogue, can induce cell apoptosis and autophapy in leukemia cells [2]. Uses: Scientific research. Group: Natural products. CAS No. 22139-77-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N2387.
Pioglitazone
Pioglitazone (U 72107) is an orally active and selective PPARγ (peroxisome proliferator-activated receptor) agonist with high affinity binding to the PPARγ ligand-binding domain with EC 50 of 0.93 and 0.99 μM for human and mouse PPARγ, respectively. Pioglitazone can be used in diabetes research [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: U 72107. CAS No. 111025-46-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-13956.
Pioglitazone hydrochloride
Pioglitazone hydrochloride is a potent and selective PPARγ agonist with EC 50 s of 0.93 and 0.99 μM for human and mouse PPARγ, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: U 72107A; AD 4833. CAS No. 112529-15-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-14601.
PIP-199
PIP-199 is a selective inhibitor of RMI (RecQ-mediated genome instability protein) core complex/MM2 interaction, with an IC50 of 36 ?M. PIP-199 can be used for the research of sensitizing resistant tumors to DNA crosslinking chemotherapeutics[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 622795-76-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-124325.
PIP5K1C-IN-1
PIP5K1C-IN-1 (Compound 30) is a potent PIP5K1C inhibitor, with an IC 50 of 0.80 nM. PIP5K1C-IN-1 exhibits low total clearance in mice and high levels of kinase selectivity. PIP5K1C-IN-1 can be used for the research of cancer and chronic pain [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3060954-15-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-163476.
Pipamperone
Pipamperone (Floropipamide; McN-JR 3345; R 3345) is a high-affinity antagonist of 5-HT 2A receptor ( pK i =8.2) and D 4 receptor ( pK i =8.0) and a low-affinity antagonist of D 2 receptor (pK i =6.7) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Floropipamide; McN-JR 3345; R 3345. CAS No. 1893-33-0. Pack Sizes: 10 mM * 1 mL; 5 mg. Product ID: HY-100703.
Pipazethate
Pipazethate (SKF 70230A), a pyridobenzothiazine derivative, is a potent GABA antagonist. Pipazethate has antitussive activity. Pipazethate can be used in research in cough supressant [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SKF 70230A; SQ 15874; Pipazetate. CAS No. 2167-85-3. Pack Sizes: 1 mg. Product ID: HY-B2090.
Pipecolic acid
Pipecolic acid is a metabolite of lysine and an immunomodulator, which can induce systemic acquired resistance (SAR) in plants. Pipecolic acid inhibits ferroptosis in diabetic retinopathy through the YAP-GPX4 signaling pathway. Pipecolic acid can induce apoptosis in neuronal cells. In addition, Pipecolic acid can be used as a diagnostic marker for pyridoxin-dependent epilepsy [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 535-75-1. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-Y0669.
Pipecuronium bromide
Pipecuronium bromide is a potent long-acting nondepolarizing steroidal neuromuscular blocking agent (NMBA), and a bisquaternary ammonium compound. Pipecuronium bromide is a powerful competitive nAChR antagonist with a K d of 3.06 μM [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 52212-02-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0743A.
Pipemidic acid
Pipemidic acid , a derivative of Piromidic acid, is an antibacterial agent. Pipemidic acid inhibits DNA gyrase. Pipemidic acid is active against gram-negative bacteria including Pseudomonas aeruginosa as well as some gram-positive bacteria. Pipemidic acid can be used for the research of intestinal, urinary, and biliary tract infections [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 51940-44-4. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-B1210.
Pipemidic acid trihydrate
Pipemidic acid trihydrate, a derivative of Piromidic acid, is an antibacterial agent. Pipemidic acid trihydrate inhibits DNA gyrase. Pipemidic acid trihydrate is active against gram-negative bacteria including Pseudomonas aeruginosa as well as some gram-positive bacteria. Pipemidic acid trihydrate can be used for the research of intestinal, urinary, and biliary tract infections [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 72571-82-5. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-W013766.
Pipequaline
Pipequaline (PK 8165) is a partial benzodiazepine receptor agonist with anxiolytic activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PK-8165. CAS No. 77472-98-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100140.
Piperacetazine
Piperacetazine is a precursor of an antipsychotic agent used in research related to schizophrenia. Uses: Scientific research. Group: Signaling pathways. CAS No. 3819-00-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B1152.
Piperacillin
Piperacillin is a semisynthetic broad-spectrum β-lactam antibiotic which exhibits potent bactericidal activity against Gram-negative bacteria as well as select Gram-positive strains through penicillin-binding proteins. Piperacillin is most commonly used in combination with the β-lactamase inhibitor Tazobactam [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Pipracil. CAS No. 61477-96-1. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B1923.
Piperacillin sodium
Piperacillin sodium is a semisynthetic broad-spectrum β-lactam antibiotic which exhibits potent bactericidal activity against Gram-negative bacteria as well as select Gram-positive strains through penicillin-binding proteins. Piperacillin is most commonly used in combination with the β-lactamase inhibitor Tazobactam [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Sodium piperacillin. CAS No. 59703-84-3. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B1286.
Piperaquine phosphate
Piperaquine phosphate is a bisquinoline antimalarial agent. Piperaquine phosphate can be used in antimalarial research in combination with Artemisinin [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 85547-56-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1896A.
Piperaquine tetraphosphate tetrahydrate
Piperaquine tetraphosphate tetrahydrate is a bisquinoline antimalarial agent. Piperaquine tetraphosphate tetrahydrate can be used in antimalarial research in combination with Artemisinin [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 915967-82-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-B1896B.
Piperazin-2-one
Piperazin-2-one is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 5625-67-2. Pack Sizes: 25 g; 100 g. Product ID: HY-20128.