MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Taurodeoxycholic acid | Taurodeoxycholate sodium salt is a bile salt-related anionic detergent. Taurodeoxycholic acid is formed in the liver by conjugation of deoxycholate with Taurine (HY-B0351). Taurodeoxycholic acid is used for isolation of membrane proteins including inner mitochondrial membrane proteins. Taurodeoxycholic acid (TDCA) exhibits anti-inflammatory and neuroprotective effects [1] [2] [3] [9] [10]. Uses: Scientific research. Group: Natural products. CAS No. 516-50-7. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-B1899. |  |
| Taurodeoxycholic acid sodium hydrate | Taurodeoxycholic acid sodium hydrate (Sodium taurodeoxycholate monohydrate), a bile acid, is an amphiphilic surfactant molecule synthesized from cholesterol in the liver. Taurodeoxycholic acid sodium hydrate activates the S1PR2 pathway in addition to the TGR5 pathway [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Sodium taurodeoxycholate monohydrate. CAS No. 110026-03-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1899A. | |
| Taurohyodeoxycholic acid | Taurohyodeoxycholic acid is the tauroconjugated form of Hyodeoxycholic acid (HDCA, a dihydroxylated natural bile acid). Taurohyodeoxycholic acid induces a biliary phospholipid secretion and suggests a hepatoprotective potential. Taurohyodeoxycholic acid also can promote gallstone dissolution [1] [1]. Uses: Scientific research. Group: Natural products. CAS No. 2958-4-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-114360. | |
| Taurohyodeoxycholic acid sodium | Taurohyodeoxycholic acid (THDCA) sodium is the taurine-conjugated form of the secondary bile acid hyodeoxycholic acid. Taurohyodeoxycholic acid can also reduce the activity and expression of myeloperoxidase TNF-α and IL-6, as well as colonic damage in TNBS-induced ulcerative colitis mouse model. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 38411-85-7. Pack Sizes: 50 mg; 100 mg. Product ID: HY-114360A. | |
| Taurolidine | Taurolidine is a potent antimicrobial and anticancer agent. Taurolidine inhibits cell proliferation. Taurolidine induces apoptosis and autophagy. Taurolidine rescues mice from sepsis-associated lethality [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 19388-87-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-W011522. | |
| Taurolithocholic acid | Taurolithocholic acid is a bile acid that has the activity of increasing cell viability, inducing the S phase of the cell cycle, and promoting DNA synthesis in a concentration-dependent manner in the intrahepatic cholangiocarcinoma cell line RMCCA-1. It can also increase the phosphorylation of EGFR and ERK 1/2 and the expression of cyclin D1 in RMCCA-1 cells, and its induced RMCCA-1 cell growth can be inhibited by specific antagonists and inhibitors. Uses: Scientific research. Group: Signaling pathways. CAS No. 516-90-5. Pack Sizes: 100 μg (206.74 μM * 1 mL in Methanol). Product ID: HY-113308. | |
| Taurolithocholic acid 3-sulfate disodium | Taurolithocholic Acid 3-sulfate (disodium) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: 3-Sulfotaurolithocholic acid disodium. CAS No. 64936-83-0. Pack Sizes: 1 mg. Product ID: HY-137255. | |
| Tauro-ω-muricholic acid sodium | Tauro-ω-muricholic acid sodium (TωMCA sodium) is a bile acid released by the liver and an analog of tauro-α-muricholic acid. Tauro-ω-muricholic acid sodium is investigated as a potential marker in plasma for early-onset neonatal sepsis (EOS) and cholestasis studies [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TωMCA sodium. CAS No. 2456348-84-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-136066. | |
| Tauroursodeoxycholate | Tauroursodeoxycholate (Tauroursodeoxycholic acid) is an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12. Tauroursodeoxycholate also inhibits ERK. Uses: Scientific research. Group: Natural products. Alternative Names: Tauroursodeoxycholic acid; TUDCA; UR 906. CAS No. 14605-22-2. Pack Sizes: 10 mM * 1 mL; 50 mg. Product ID: HY-19696. | |
| Tauroursodeoxycholate sodium | Tauroursodeoxycholate (Tauroursodeoxycholic acid; TUDCA) sodium is an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12. Tauroursodeoxycholate also inhibits ERK. Uses: Scientific research. Group: Natural products. Alternative Names: Tauroursodeoxycholic acid sodium; TUDCA sodium; UR 906 sodium. CAS No. 35807-85-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-19696A. | |
| Tavaborole | Tavaborole (AN-2690) is an antifungal agent with activity against Trichophyton species, in a topical solution formulation for the potential treatment of onychomycosis. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AN-2690. CAS No. 174671-46-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10980. | |
| Tavapadon | Tavapadon (PF-06649751) is an orally active and highly selective dopamine D1/D5 receptor partial agonist. Tavapadon is effective in enabling movement and reducing disability and has the potential for Parkinson's disease [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PF-06649751; CVL-751. CAS No. 1643489-24-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119486. | |
| Tavilermide | Tavilermide is a selective, partial agonist of TrkA , or a nerve growth factor (NGF) mimetic. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MIM-D3. CAS No. 263251-78-1. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17622. | |
| Taxifolin | Taxifolin ((+)-Dihydroquercetin) exhibits important anti- tyrosinase activity. Taxifolin exhibits significant inhibitory activity against collagenase with an IC 50 value of 193.3 μM [1]. Taxifolin is an important natural compound with antifibrotic activity. Taxifolin is a free radical scavenger with antioxidant capacity [2]. Uses: Scientific research. Group: Natural products. Alternative Names: (+)-Dihydroquercetin; (+)-Taxifolin. CAS No. 480-18-2. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-N0136. | |
| (-)-Taxifolin | (-)-Taxifolin is the less active enantiomer of Taxifolin. Taxifolin exhibits important anti- tyrosinase activity. Taxifolin exhibits significant inhibitory activity against collagenase with an IC 50 value of 193.3 μM [1]. Taxifolin is an important natural compound with antifibrotic activity. Taxifolin is a free radical scavenger with antioxidant capacity [2]. Uses: Scientific research. Group: Natural products. Alternative Names: (-)-Dihydroquercetin. CAS No. 111003-33-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N0136B. | |
| (±)-Taxifolin | (±)-Taxifolin ((±)-Dihydroquercetin) is the racemate of Taxifolin. Taxifolin exhibits important anti- tyrosinase activity. Taxifolin exhibits significant inhibitory activity against collagenase with an IC 50 value of 193.3 μM [1]. Taxifolin is an important natural compound with antifibrotic activity. Taxifolin is a free radical scavenger with antioxidant capacity [2]. Uses: Scientific research. Group: Natural products. Alternative Names: (±)-Dihydroquercetin. CAS No. 24198-97-8. Pack Sizes: 50 mg; 100 mg. Product ID: HY-N0136A. | |
| Tazarotene | Tazarotene (AGN 190168) is a selective retinoic acid receptor ( RAR ) agonist for the treatment of plaque psoriasis and acne vulgaris. Tazarotene is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AGN 190168. CAS No. 118292-40-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15388. | |
| Tazarotenic acid | Tazarotenic acid is the metabolite of Tazarotene. Tazarotenic acid binding to retinoic acid receptors (RARs) is the probable molecular target of retinoid action. Tazarotenic acid has the potential for the research of warty dyskeratoma [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AGN 190299. CAS No. 118292-41-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101108. | |
| Tazemetostat | Tazemetostat (EPZ-6438) is a potent, selective and orally available EZH2 inhibitor. Tazemetostat inhibits the activity of human polycomb repressive complex 2 (PRC2)-containing wild-type EZH2 with a K i value of 2.5 nM. Tazemetostat inhibits EZH2 with IC 50 s of 11 and 16 nM in peptide assay and nucleosome assay, respectively. Tazemetostat inhibits rat EZH2 with an IC 50 of 4 nM. Tazemetostat also inhibits EZH1 with an IC 50 of 392 nM. Tazemetostat induces apoptosis and differentiation specifically in SMARCB1-deleted MRT cells [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EPZ-6438; E-7438. CAS No. 1403254-99-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-13803. | |
| Tazobactam | Tazobactam (CL-298741) is a potent β-lactamases inhibitor and penicillin antibiotic. Tazobactam has antibacterial activity. Tazobactam can be used for pneumonia research [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: CL-298741; YTR-830H. CAS No. 89786-04-9. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-B1418. | |
| Tazobactam sodium | Tazobactam sodium is an antibiotic of the beta-lactamase inhibitor class. Ceftolozane combines with Tazobactam, extends the activity of ceftolozane against many ESBL-producing Enterobacteriaceae and some Bacteroides spp. Uses: Scientific research. Group: Signaling pathways. CAS No. 89785-84-2. Pack Sizes: 50 mg; 100 mg. Product ID: HY-W009168. | |
| TB5 | TB5 is a potent, selective and reversible inhibitor of hMAO-B with a K i value of 0.11±0.01 μM. Uses: Scientific research. Group: Signaling pathways. CAS No. 948841-07-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100975. | |
| TB500 | TB500 is a synthetic version of an active region of thymosin β 4. TB500 is claimed to promote endothelial cell differentiation, angiogenesis in dermal tissues, keratinocyte migration, collagen deposition and decrease inflammation [1]. Uses: Scientific research. Group: Peptides. CAS No. 885340-08-9. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P0170. | |
| TBAJ-876 | TBAJ-876 is the inhibitor of mycobacterium tuberculosis. TBAJ-876 is the analogue of the anti-tuberculosis agent Bedaquiline. TBAJ-876 has the potential for the research of tuberculosis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2332841-25-3. Pack Sizes: 1 mg. Product ID: HY-128866. | |
| TBB | TBB is a cell-permeable and ATP-competitive CK2 inhibitor with an IC 50 of 0.15 μM for rat liver CK2. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NSC 231634; Casein Kinase II Inhibitor I. CAS No. 17374-26-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14394. | |
| TBCA | TBCA is a highly selective CK2 (casein kinase II) inhibitor with an IC 50 of 110 nM and a K i of 77 nM. TBCA shows selectivity for CK2 over CK1, DYRK1A and a panel of 27 other kinases [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 934358-00-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110052. | |
| TBHQ | TBHQ (tert-Butylhydroquinone) is a widely used Nrf2 activator, protects against Doxorubicin (DOX)-induced cardiotoxicity through activation of Nrf2 [1]. TBHQ (tert-Butylhydroquinone) is also an ERK activator; rescues Dehydrocorydaline (DHC)-induced cell proliferation inhibitionin melanoma [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: tert-Butylhydroquinone. CAS No. 1948-33-0. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-100489. | |
| TBHQ (Standard) | TBHQ (Standard) is the analytical standard of TBHQ. This product is intended for research and analytical applications. TBHQ (tert-Butylhydroquinone) is a widely used Nrf2 activator, protects against Doxorubicin (DOX)-induced cardiotoxicity through activation of Nrf2 [1]. TBHQ (tert-Butylhydroquinone) is also an ERK activator; rescues Dehydrocorydaline (DHC)-induced cell proliferation inhibitionin melanoma [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: tert-Butylhydroquinone (Standard). CAS No. 1948-33-0. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-100489R. | |
| TBI-223 | TBI-223 is an orally bioavailable oxazolidinone antibiotic and an antimicrobial. TBI-223 shows activity against Mycobacterium tuberculosis (Mtb) [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2071265-08-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139398. | |
| tBID | tBID is a selective inhibitor of homeodomain-interacting protein kinase 2 ( HIPK2 ) with an IC 50 of ?0.33 μM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1639895-85-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-100464. | |
| TBPB | TBPB is an allosteric M1 mAChR agonist(EC50=289 nM) that regulates amyloid processing and produces antipsychotic-like activity in rats. Uses: Scientific research. Group: Signaling pathways. CAS No. 634616-95-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-14562. | |
| TbPTR1 inhibitor 2 | TbPTR1 inhibitor 2 (Compound 3a) is a PTR1 enzyme inhibitor, with IC 50 s of 34.2 and 32.9 μM for Tb PTR1 and Lm PTR1. TbPTR1 inhibitor 2 has anti-parasitic activity against T. brucei ( IC 50 : 34.2 μM) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 17557-67-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W009689. | |
| TC11 | TC11 is a MCL1 degrader and Caspase-9 and CDK1 activator. TC11 functions as a phenylacetylamide derivative and is structurally related to immunomodulatory active molecules. TC11 induces degradation of MCL1 leading to apoptotic death [1] [2] during prolonged mitotic arrest. Uses: Scientific research. Group: Signaling pathways. CAS No. 100823-03-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129478. | |
| TCB2 | TCB2 is an agonist of serotonin 5-HT 2A receptor. Uses: Scientific research. Group: Signaling pathways. CAS No. 912342-28-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103102. | |
| TC-E 5003 | TC-E 5003 is a selective protein arginine methyltransferase 1 ( PRMT1 ) inhibitor with an IC 50 of 1.5 μM against hPRMT1. TC-E 5003 modulates the lipopolysaccharide (LPS) (HY-D1056)-induced AP-1 and NF-κB signaling pathways with anti-inflammatory properties. TC-E 5003 also upregulates the expression of Ucp1 and Fgf21, activates protein kinase A signaling and lipolysis in primary subcutaneous adipocytes from both mouse and humans. TC-E 5003 is promising for research of obesity and associated metabolic disorders, oxidative stress, inflammation and cancers [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 17328-16-4. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-107574. | |
| TCEP hydrochloride | TCEP hydrochloride (Tris(2-carboxyethyl)phosphine hydrochloride) is a non-thiol reducing agent that is more stable and produces a faster S-S reductive reaction than other chemical reductants. TCEP hydrochloride is a trialkylphosphine, selectively reduces protein disuldes without altering the properties or interacting with thiol-directed agents in the reaction mixture. TCEP hydrochloride is also a commonly used reducing agent in the DNA/AuNP chemistry [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Tris(2-carboxyethyl)?phosphine hydrochloride. CAS No. 51805-45-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-W011500. | |
| TCID | TCID (4,5,6,7-Tetrachloroindan-1,3-dione) is a potent and selective neuronal ubiquitin C-terminal hydrolase (UCH-L3) inhibitor with an IC 50 of 0.6 μM [1]. TCID diminishes glycine transporter GlyT2 ubiquitination in brainstem and spinal cord primary neurons [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 4,5,6,7-Tetrachloroindan-1,3-dione. CAS No. 30675-13-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-18638. | |
| TC LPA5 4 | TC LPA5 4 is a LPA 5 (GPR92) -specific non-lipid antagonist. TC LPA5 4 inhibits LPA-induced aggregation of isolated human platelet (LPA 5 -RH7777 cell line) with an IC 50 of 800 nM. TC LPA5 4 displays selectivity for LPA 5 over 80 other screened agent targets [1]. TC LPA5 4 inhibits cell proliferation and migration of thyroid cancer cells [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1393814-38-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107615. | |
| TCMCB07 | TCMCB07, a cyclic nonapeptide peptide, is an orally active and brain-penetrant melanocortin receptor 4 (MC4R) antagonist. TCMCB07 plays an important role in cachexia [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Mifomelatide. CAS No. 1456699-27-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P5971. | |
| TCMDC-135051 | TCMDC-135051 is a highly selective and potent protein kinase Pf CLK3 inhibitor with low off-target toxicity. TCMDC-135051 prevents trophozoite-to-schizont transition, disrupts transcription and reduces transmission to the mosquito vector. TCMDC-135051 has antiparasiticidal activity (EC 50 =320 nM) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2413716-15-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126323. | |
| TCMDC-135051 hydrochloride | TCMDC-135051 hydrochloride is a highly selective and potent protein kinase Pf CLK3 inhibitor with low off-target toxicity. TCMDC-135051 hydrochloride prevents trophozoite-to-schizont transition, disrupts transcription and reduces transmission to the mosquito vector. TCMDC-135051 hydrochloride has antiparasiticidal activity (EC 50 =320 nM) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2705545-47-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-126323B. | |
| TCMTB | TCMTB is one of the so-called emerging contaminants (EC). TCMTB is also an antifouling agent [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 21564-17-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101425. | |
| TCO-NHS ester | TCO-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs [1]. TCO-NHS ester is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1191901-33-3. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-141165. | |
| TCO-PEG3-maleimide | TCO-PEG3-maleimide (TCO-PEG3-NEM) is a click chemistry reagent. TCO-PEG3-maleimide efficiently binds TCO (trans-cyclooctene) moiety to thiol-containing molecules (such as antibodies, cysteine-containing peptides) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1809356-72-6. Pack Sizes: 5 mg. Product ID: HY-151696. | |
| TCO-PEG4-NHS ester | TCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs [1]. TCO-PEG4-NHS ester is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1621096-79-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141167A. | |
| TCS-OX2-29 | TCS-OX2-29 is a potent, high affinities and selective orexin-2 receptor (OX 2 R) antagonist with an IC 50 value of 40 nM and a pK I value of 7.5. TCS-OX2-29 displays ~250-fold selectivity for OX 2 over OX 1 [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 372523-75-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100452. | |
| TCTDSTNCYKAT | TCTDSTNCYKAT is an engineered-variant peptide of antifreeze protein (AFP) [1]. Uses: Scientific research. Group: Peptides. CAS No. 1621188-94-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P3158. | |
| tcY-NH2 TFA | tcY-NH2 ((trans-Cinnamoyl)-YPGKF-NH2) TFA is a potent selective PAR4 antagonist peptide. tcY-NH2 TFA inhibits thrombin- and AY-NH 2 -induced platelet aggregation and endostatin release, and can be used in the research of inflammation, immunology [1] [2] [6]. Uses: Scientific research. Group: Peptides. Alternative Names: (trans-Cinnamoyl)-YPGKF-NH2 TFA. CAS No. 1262750-73-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1263A. | |
| TD-165 | TD-165 is a PROTAC-based cereblon ( CRBN ) degrader. TD-165 comprises a cereblon (CRBN) ligand binding group, a linker and an von Hippel-Landau (VHL) binding group [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2305936-56-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130714. | |
| TD52 | TD52, an Erlotinib (HY-50896) derivative, is an orally active, potent cancerous inhibitor of protein phosphatase 2A (CIP2A) inhibitor. TD52 mediates the apoptotic effect in triple-negative breast cancer (TNBC) cells via regulating the CIP2A/PP2A/p-Akt signalling pathway. TD52 indirectly reduced CIP2A by disturbing Elk1 binding to the CIP2A promoter. TD52 has less p-EGFR inhibition and has potent anti-cancer activity [1]. TD52 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1798328-24-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135699. | |
| TDCPP | TDCPP is a chlorinated analog of tris(2,3-dibromopropyl)phosphate (Tris) which is one of the most detected organophosphorus flame retardants (OPFRs) in the environment. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Tris(1,3-dichloroisopropyl)phosphate. CAS No. 13674-87-8. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-108712. | |
| TDZD-8 | TDZD-8 is an inhibitor of GSK-3β , with an IC 50 of 2 μM; TDZD-8 shows less potent activities against Cdk-1/cyclin?B, CK-II, PKA, and PKC, with all IC 50 s of >100 μM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GSK-3β Inhibitor I; NP 01139. CAS No. 327036-89-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-11012. | |
| Tea polyphenol | Tea polyphenol is the floorboard of phenolic compounds in tea. Tea polyphenol exhibits biological activity including antioxidant and anti-cancer activities, inhibition of cell proliferation, induction of apoptosis, cell cycle arrest and modulation of carcinogen metabolism [1]. Uses: Scientific research. Group: Natural products. CAS No. 84650-60-2. Pack Sizes: 1 g. Product ID: HY-N1925. | |
| Tebapivat | Tebapivat (PKR activator 2) is a potent pyruvate kinase-R (PKR) activator extracted from patent WO2019035863A1, compound 385 [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AG-946; PKR activator 2. CAS No. 2283422-04-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-135884. | |
| Tebentafusp | Tebentafusp (IMCgp100) is a bispecific fusion protein to target gp100 peptide-HLA-A*02:01 (a melanoma-associated antigen). Tebentafusp guides T cells to kill gp100 -expressing tumor cells via a high affinity T-cell receptor (TCR) binding domain and an anti-CD3 T-cell engaging domain. Tebentafusp leads to inflammatory cytokines and cytolytic proteins production, resulting in the direct lysis of tumour cells [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: IMCgp100. CAS No. 1874157-95-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99339. | |
| Tebipenem | Tebipenem is an orally available carbapenem antibiotic, shows broad-spectrum activity against Gram-positive and -negative bacteria, except for Pseudomonas aeruginosa. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LJC 11036. CAS No. 161715-21-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0076. | |
| Tebipenem pivoxil | Tebipenem pivoxil (L084) is an orally active antibiotic against a variety of pathogenic bacteria. Tebipenem pivoxil binds penicillin-binding protein (PBP), thereby inhibiting cell wall synthesis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: L084. CAS No. 161715-24-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0396. | |
| Tebotelimab | Tebotelimab (MGD-013) is a humanized IgG4κ bispecific PD-1/LAG-3 dual-affinity re-targeting (DART) antibody. Tebotelimab binds cell-surface expressed PD-1 and LAG-3 with EC 50 s of 1.65 nM and 0.41 nM in NS0 cells, respectively. Tebotelimab blocks PD-1/PD-L1, PD-1/PD-L2 and LAG-3/HLA (MHC-II) interactions and PD-1 signaling. Tebotelimab restores exhausted T-cell responses and and enhances antitumour immunity [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MGD-013. CAS No. 2245725-04-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99573. | |
| Tebuconazole | Tebuconazole is an orally active agricultural azole fungicide which can also inhibit CYP51 with IC 50 s of 0.9 and 1.3 μM for Candida albicans CYP51 ( CaCYP51 ) and truncated Homo sapiens CYP51 ( Δ60HsCYP51 ), respectively. Tebuconazole induces lipid accumulation and oxidative stress in HepG2 Cells. Tebuconazole decreases MAC-T cells viability and proliferation, induces ER-stress-mediated apoptosis and increases oxidative stress levels in MAC-T cells [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. CAS No. 107534-96-3. Pack Sizes: 10 mM * 1 mL; 200 mg; 1 g. Product ID: HY-B0852. | |
| Tebuconazole (Standard) | Tebuconazole (Standard) is the analytical standard of Tebuconazole. This product is intended for research and analytical applications. Tebuconazole is an orally active agricultural azole fungicide which can also inhibit CYP51 with IC 50 s of 0.9 and 1.3 μM for Candida albicans CYP51 ( CaCYP51 ) and truncated Homo sapiens CYP51 ( Δ60HsCYP51 ), respectively. Tebuconazole induces lipid accumulation and oxidative stress in HepG2 Cells. Tebuconazole decreases MAC-T cells viability and proliferation, induces ER-stress-mediated apoptosis and increases oxidative stress levels in MAC-T cells [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. CAS No. 107534-96-3. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0852R. | |
| Tebufenozide | Tebufenozide is a nonsteroidal ecdysone agonist used to control pest. Tebufenozide has cytotoxic and induces apoptosis in HeLa and insect Tn5B1-4 cells [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 112410-23-8. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-B2054. | |
| Tebufenpyrad | Tebufenpyrad can induce mitochondrial dysfunction and oxidative damage. Tebufenpyrad induces dose-dependent cell death on N27 cells, with an EC 50 value of 3.98 μM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 119168-77-3. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-B1914. | |
| Tecadenoson | Tecadenoson (CVT-510) is a selective A1 adenosine receptor agonist. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CVT-510. CAS No. 204512-90-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19661. | |
| Tecarfarin | Tecarfarin (ATI-5923) is an orally active and non-competitive vitamin K epoxide reductase ( VKOR ) antagonist, and impairs the activation of the vitamin K-dependent clotting factors II, VII, IX and X [1]. Tecarfarin has the antithrombotic activity [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ATI-5923. CAS No. 867257-26-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14854. | |
| Tecastemizole | Tecastemizole (Norastemizole), a major metabolite of Astemizole, is a potent and selective H1 receptor antagonist. Tecastemizole shows anti-inflammatory activities [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Norastemizole. CAS No. 75970-99-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-105014. | |
| Teclistamab | Teclistamab is a human bispecific antibody to BCMA and CD3 that recognizes BCMA on target cells and CD3 on T cells and induces T cell-mediated cytotoxicity leading to T cell activation and subsequent target cell lysis. Teclistamab can be used in studies of diseases related to multiple myeloma (MM) [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2119595-80-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99392. | |
| Teclozan | Teclozan (WIN 13146) is an antiprotozoal agent, class in benzylamine derivatives. Teclozan intervenes in the phospholipid metabolism preventes the formation of arachidonic acid. Teclozan acts in the intestinal lumen being effective in Anti- G. intestinalis. Teclozan can be used for the research of protozoan infections [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: WIN 13146. CAS No. 5560-78-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19594. | |
| Tecnazene | Tecnazene (2,3,5,6-Tetrachloronitrobenzene) is a fungicide and is used as a sprout inhibitor on stored potatoes [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 117-18-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-121935. | |
| Tecovirimat | Tecovirimat (ST-246) is an orally bioavailable and selective compound against orthopoxviruses including vaccinia, monkeypox, camelpox, cowpox, ectromelia (mousepox), smallpox and variola viruses. Tecovirimat is evaluated against vaccinia, cowpox virus, ectromelia virus with EC 50 values of 0.01 μM, 0.48 μM and 0.05 μM, respectively. Tecovirimat targets the orthopoxvirus protein VP37 which is necessary for membrane envelopment of intracellular mature virus particles to form enveloped virus. Tecovirimat exerts antiviral activity on the target of the cowpox virus V061 gene , which is homologous to vaccinia virus F13L , encoding a major envelope protein (p37) required for production of extracellular virus [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ST-246. CAS No. 869572-92-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14805. | |
| Tecovirimat monohydrate | Tecovirimat (ST-246) monohydrate is the monohydrate form of Tecovirimat (HY-14805). Tecovirimat monohydrate is an orally bioavailable and selective compound against orthopoxviruses [including vaccinia, monkeypox, camelpox, cowpox, ectromelia (mousepox), smallpox and variola viruses]. Tecovirimat monohydrate is evaluated against vaccinia, cowpox virus, ectromelia virus with EC 50 values of 0.01 μM, 0.48 μM and 0.05 μM, respectively. Tecovirimat monohydrate targets the orthopoxvirus protein VP37 which is necessary for membrane envelopment of intracellular mature virus particles to form enveloped virus. Tecovirimat monohydrate exerts antiviral activity on the target of the cowpox virus V061 gene , which is homologous to vaccinia virus F13L , encoding a major envelope protein (p37) required for production of extracellular virus. Tecovirimat monohydrate could be used in the study for orthopoxvirus-induced diseases [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ST-246 monohydrate. CAS No. 1162664-19-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14805A. | |
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