MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| TAME hydrochloride | TAME hydrochloride is an inhibitor of anaphase-promoting complex/cyclosome (APC/C or APC) , which binds to APC/C and prevents its activation by Cdc20 and Cdh1, produces mitotic arrest. TAME hydrochloride is not cell permeable [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1784-03-8. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-13255A. |  |
| Tamibarotene | Tamibarotene is an orally active retinoic acid receptor α (RARα) agonist, showing high selectivity over RAR&gamma. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Am 80. CAS No. 94497-51-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-14652. | |
| Tamnorzatinib | Tamnorzatinib (ONO-7475) is a potent, selective, and orally active Axl/Mer inhibitor with IC50 values of 0.7 nM and 1.0 nM, respectively. Tamnorzatinib sensitizes AXL-overexpressing EGFR-mutant NSCLC cells to the EGFR-TKIs, suppresses the emergence and maintenance of tolerant cells. Tamnorzatinib combines with Osimertinib (HY-15772) provides a bright promise for the study of EGFR-mutated non-small cell lung cancer (NSCLC). Uses: Scientific research. Group: Signaling pathways. Alternative Names: ONO-7475. CAS No. 1646839-59-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114358. | |
| Tamoxifen | Tamoxifen (ICI 47699) is an orally active, selective estrogen receptor modulator ( SERM ) which blocks estrogen action in breast cells and can activate estrogen activity in other cells, such as bone, liver, and uterine cells [1] [2] [3]. Tamoxifen is a potent Hsp90 activator and enhances the Hsp90 molecular chaperone ATPase activity. Tamoxifen also potent inhibits infectious EBOV Zaire and Marburg (MARV) with IC 50 of 0.1 μM and 1.8 μM, respectively [5]. Tamoxifen activates autophagy and induces apoptosis [4]. Tamoxifen also can induce gene knockout of CreER transgenic mouse [6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ICI 47699; (Z)-Tamoxifen; trans-Tamoxifen. CAS No. 10540-29-1. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg; 1 g; 5 g. Product ID: HY-13757A. | |
| Tamoxifen Citrate | Tamoxifen Citrate (ICI 46474) is an orally active, selective estrogen receptor modulator ( SERM ) which blocks estrogen action in breast cells and can activate estrogen activity in other cells, such as bone, liver, and uterine cells [1] [2] [3].Tamoxifen Citrate is a potent Hsp90 activator and enhances the Hsp90 molecular chaperone ATPase activity. Tamoxifen Citrate also potent inhibits infectious EBOV Zaire and Marburg (MARV) with IC 50 of 0.1 μM and 1.8 μM, respectively [5]. Tamoxifen Citrate activates autophagy and induces apoptosis [4]. Tamoxifen Citrate also can induce gene knockout of CreER transgenic mouse [6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ICI 46474; (Z)-Tamoxifen Citrate; trans-Tamoxifen Citrate. CAS No. 54965-24-1. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-13757. | |
| Tamoxifen (Standard) | Tamoxifen (Standard) is the analytical standard of Tamoxifen (HY-13757A). This product is intended for research and analytical applications. Tamoxifen (ICI 47699) is an orally active, selective estrogen receptor modulator ( SERM ) which blocks estrogen action in breast cells and can activate estrogen activity in other cells, such as bone, liver, and uterine cells [1] [2] [3]. Tamoxifen is a potent Hsp90 activator and enhances the Hsp90 molecular chaperone ATPase activity. Tamoxifen also potent inhibits infectious EBOV Zaire and Marburg (MARV) with IC 50 of 0.1 μM and 1.8 μM, respectively [5]. Tamoxifen activates autophagy and induces apoptosis [4]. Tamoxifen also can induce gene knockout of CreER(T2) transgenic mouse [6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ICI 47699(Standard); (Z)-Tamoxifen(Standard); trans-Tamoxifen (Standard). CAS No. 10540-29-1. Pack Sizes: 10 mg; 25 mg; 50 mg. Product ID: HY-13757AR. | |
| TAMRA azide, 5-isomer | TAMRA azide, 5-isomer is a click chemical containing azide groups that can be used as a linker for the orange dye TAMRA. The azide group of TAMRA Azide, 5-isomer enables copper-catalyzed click chemical reactions with alkynes, DBCO, and BCN [1] [2]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. Uses: Scientific research. Group: Fluorescent dye. CAS No. 825651-66-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-151857. | |
| TAMRA azide, 6-isomer | TAMRA azide, 6-isomer is an isomer of TAMRA, a xanthene dye with orange emission. Uses: Scientific research. Group: Fluorescent dye. CAS No. 1192590-89-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D1306. | |
| TAMRA-PEG3-Azide | TAMRA-PEG3-Azide is a dye derivative of TAMRA (HY-135640) containing 3 PEG units. TAMRA-PEG3-Azide contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Group: Fluorescent dye. CAS No. 1228100-59-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-123629. | |
| Tamrintamab | Tamrintamab (SC-003 mAb, SC-Mab003, SC34.28ss1) is an ADC Antibody targeting to dipeptidase 3 ( DPEP3 or MBD3 ). DPEP3 is a glycosyl phosphatidylinositol anchored metallopeptidase that is overexpressed in ovarian tumors. Tamrintamab can specifically bind DPEP3-expressing cells to produce cytotoxicity. Tamrintamab can be used in ovarian cancer research [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: SC-003 mAb; SC-Mab003; SC34.28ss1. CAS No. 2148325-59-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99506. | |
| Tamsulosin | Tamsulosin ((R)-(-)-YM12617 free base) is an orally active antagonist of α 1 -adrenergic receptor. Tamsulosin induces Apoptosis. Tamsulosin is used for the research of prostatic hyperplasia. Tamsulosin attenuates abdominal aortic aneurysm growth and inhibits inflammation in animal models [1] [2] [3] [4] [5] [6] [7] [8]. Uses: Scientific research. Group: Natural products. Alternative Names: (R)-(-)-YM12617 free base; LY253351 free base. CAS No. 106133-20-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0661. | |
| Tamsulosin hydrochloride | Tamsulosin hydrochloride ((R)-(-)-YM12617 free base) is an orally active antagonist of α 1 -adrenergic receptor. Tamsulosin hydrochloride induces Apoptosis. Tamsulosin hydrochloride is used for the research of prostatic hyperplasia. Tamsulosin hydrochloride attenuates abdominal aortic aneurysm growth and inhibits inflammation in animal models [1] [2] [3] [4] [5] [6] [7] [8]. Uses: Scientific research. Group: Natural products. Alternative Names: (R)-(-)-YM12617; LY253351. CAS No. 106463-17-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0661A. | |
| Tandospirone | Tandospirone (SM-3997) is a potent and selective 5-HT 1A receptor partial agonist, with a K i of 27 nM. Tandospirone has anxiolytic and antidepressant activities. Tandospirone can be used for the research of the central nervous system disorders and the underlying mechanisms [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SM-3997. CAS No. 87760-53-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14558. | |
| Tandospirone citrate | Tandospirone citrate is a potent and selective 5-HT1A receptor partial agonist (Ki = 27 nM) that displays selectivity over SR-2, SR-1C, α1, α2, D1 and D2 receptors (Ki values ranging from 1300-41000 nM). Uses: Scientific research. Group: Signaling pathways. Alternative Names: SM-3997 citrate. CAS No. 112457-95-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0061. | |
| Tandutinib | Tandutinib (MLN518) is a potent and selective inhibitor of the FLT3 with an IC 50 of 0.22 μM, and also inhibits c-Kit and PDGFR with IC 50 s of 0.17 μM and 0.20 μM, respectively. Tandutinib can be used for acute myelogenous leukemia (AML) [1] [2]. Tandutinib has the ability to cross the blood-brain barrier [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MLN518; CT53518. CAS No. 387867-13-2. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-10202. | |
| Tandutinib hydrochloride | Tandutinib hydrochloride (MLN518 hydrochloride) is a potent and selective inhibitor of the FLT3 with an IC 50 of 0.22 μM, and also inhibits c-Kit and PDGFR with IC 50 s of 0.17 μM and 0.20 μM, respectively. Tandutinib hydrochloride can be used for acute myelogenous leukemia (AML) [1] [2]. Tandutinib hydrochloride has the ability to cross the blood-brain barrier [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MLN518 hydrochloride; CT53518 hydrochloride. CAS No. 2438900-70-8. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-10202A. | |
| Tanespimycin | Tanespimycin (17-AAG) is a potent HSP90 inhibitor with an IC 50 of 5 nM, having a 100-fold higher binding affinity for tumour cell derived HSP90 than normal cell derived HSP90 [1] [5]. Tanespimycin depletes cellular STK38/NDR1 and reduces STK38 kinase activity. Tanespimycin also downregulates the stk38 gene expression [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 17-AAG; NSC 330507; CP 127374. CAS No. 75747-14-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 100 mg; 200 mg. Product ID: HY-10211. | |
| Tanezumab | Tanezumab (RN-624) is a humanized anti- NGF mAb with high affinity and specificity. Tanezumab blocks NGF binding to its receptors, p75 and TrkA , in the peripheral nervous system. Tanezumab can be used in studies of acute and chronic pain such as osteoarthritis, knee and neuralgia, as well as post-herpetic neuralgia [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: RN-624; PF 4383119. CAS No. 880266-57-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99221. | |
| Tangeretin | Tangeretin (Tangeritin), a flavonoid from citrus fruit peels, has been proven to play an important role in anti-inflammatory responses and neuroprotective effects in several disease models, and is a Notch-1 inhibitor. Uses: Scientific research. Group: Natural products. Alternative Names: Tangeritin; NSC53909; NSC618905. CAS No. 481-53-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0133. | |
| Taniborbactam hydrochloride | Taniborbactam hydrochloride (VNRX-5133 hydrochloride) is a reversible and selective boronic acid-containing pan-spectrum β-lactamase inhibitor with IC 50 s of 8-530 nM. Taniborbactam hydrochloride has IC 50 s of 30 nM, 32 nM, 42 nM, 20 nM for KPC-2, AmpC, OXA-48, and VIM-2. Taniborbactam hydrochloride is against Gram-negative bacteria [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: VNRX-5133 hydrochloride. CAS No. 2244235-49-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-109124A. | |
| Tanimilast | Tanimilast (CHF-6001) is a novel highly potent and selective phosphodiesterase 4 inhibitor( IC 50 =0.026 ± 0.006 nM) with robust anti-inflammatory activity and suitable for topical pulmonary administration.Tanimilast is used for the research of obstructive lung diseases [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CHF-6001. CAS No. 1239278-59-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19929. | |
| Tannase | Tannase, also known as tanninyl hydrolase, is an enzyme that can hydrolyze ester bonds and tannic acid side bonds, releasing glucose and gallic acid, and is outstanding in clarifying wine and fruit juice [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 9025-71-2. Pack Sizes: 1 g; 5 g. Product ID: HY-P2877. | |
| Tannic acid | Tannic acid is a novel hERG channel blocker with IC 50 of 3.4 μM. Uses: Scientific research. Group: Natural products. CAS No. 1401-55-4. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B2136. | |
| tans-4-Hydroxy-D-proline hydrochloride | tans-4-Hydroxy-D-proline hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). tans-4-Hydroxy-D-proline hydrochloride is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PR. Uses: Scientific research. Group: Signaling pathways. CAS No. 142347-81-7. Pack Sizes: 1 g; 5 g. Product ID: HY-W003511. | |
| Tanshinone I | Tanshinone I is an inhibitor of type IIA human recombinant sPLA 2 ( IC 50 =11 μM) and rabbit recombinant cPLA 2 ( IC 50 =82 μM). Uses: Scientific research. Group: Natural products. Alternative Names: Tanshinone A. CAS No. 568-73-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0134. | |
| Tanshinone IIA | Tanshinone IIA (Tan IIA) is one of the main compositions in the root of Salvia miltiorrhiza Bunge. Tanshinone IIA may suppress angiogenesis by targeting the protein kinase domains of VEGF / VEGFR2. Uses: Scientific research. Group: Natural products. Alternative Names: Dan Shen ketone. CAS No. 568-72-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N0135. | |
| Tanshinone IIA sulfonate sodium | Tanshinone IIA sulfonate (sodium) is a derivative of tanshinone IIA, which acts as an inhibitor of store-operated Ca 2+ entry (SOCE), and is used to treat cardiovascular disorders. Uses: Scientific research. Group: Natural products. Alternative Names: Sodium Tanshinone IIA sulfonate; Tanshinone IIA sodium sulfonate. CAS No. 69659-80-9. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-N1370. | |
| Tanuxiciclib | Tanuxiciclib is a cyclin dependent kinase (CDK) inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1983983-64-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145599. | |
| TAPI-0 | TAPI-0 is a TACE (TNF-α converting enzyme; ADAM17) inhibitor with an IC 50 of 100 nM. TAPI-0 is a MMP inhibitor and also attenuates TNF-α processing [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 163958-73-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-118694. | |
| TAPI-2 | TAPI-2 (TNF Protease Inhibitor 2) is a broad-spectrum inhibitor of matrix metalloprotease ( MMP ), tumour necrosis factor α -converting enzyme ( TACE ) and a disintegrin and metalloproteinase ( ADAM ), with an IC 50 of 20 μM for MMP [1]. TAPI-2 blocks the entry of infectious SARS-CoV [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TNF Protease Inhibitor 2. CAS No. 187034-31-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100211. | |
| Tapinarof | Tapinarof (WBI-1001) is a natural aryl hydrocarbon receptor ( AhR ) agonist with an EC 50 of 13 nM. Tapinarof resolves skin inflammation in mice [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: WBI-1001; Benvitimod; GSK2894512. CAS No. 79338-84-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-109044. | |
| Taplucainium chloride | Taplucainium chloride is a Sodium Channel blocker. Taplucainium chloride exhibits 70-95% inhibition at 10μM. Taplucainium chloride can be used as an analgesic agent [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2489565-37-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148802. | |
| TAPS | TAPS is a biological buffer, remain lysozyme native structure intact and prevents thermal denaturation against high temperatures. TAPS exhibits pK a value of 8.1, while the half-maximum values of connexin channel activity is 8.5 (pH) [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 29915-38-6. Pack Sizes: 25 g; 50 g. Product ID: HY-D0877. | |
| TAPSO | TAPSO is a common biological buffer, a pH stabilization reagent, with effective pH ranging from 7-8, and pKa values ranging from 7.5 - 9.0. TAPSO contains Tris groups and exhibits quite reactive activity with zwitterionic glycine peptides [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 68399-81-5. Pack Sizes: 25 g; 100 g. Product ID: HY-D0878. | |
| Taq DNA polymerase | Taq DNA polymerase is a thermostable DNA polymerase that can be used in PCR [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2304873-37-6. Pack Sizes: 500 U. Product ID: HY-E70086. | |
| Taraxasterol | Taraxasterol is a pentacyclic triterpenoid compound isolated from Taraxacum mongolicum. Taraxasterol is an LXRα activator, with metabolic and anti-inflammatory effects. Taraxasterol may be used in research on immune-inflammatory diseases [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 1059-14-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N1178. | |
| Taraxasteryl acetate | Taraxasteryl acetate is isolated from P. sagittalis ,and has a broad spectrum of anti-inflammatory activity. Taraxasterol acetate promotes RNF31 degradation by activating autophagy. Taraxasteryl acetate relieves dextran, zymosan and arachidonic acid induced rat hind-paw edema. Taraxasteryl acetate can be used for the topical inflammation treatment [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 6426-43-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N2478. | |
| Taraxerol | Taraxerol is isolated from Taraxacum mongolicum , and has anti-inflammtory and anti-cancer effects. Taraxerol attenuates acute inlammation through inhibition of NF-κB signaling pathway. Taraxerol induces cell apoptosis [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 127-22-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N2477. | |
| Taraxerone | Taraxerone is isolated from Sedum sarmentosum. Taraxerone enhances effects on alcohol dehydrogenase ( ADH ) and acetaldehyde dehydrogenase ( ALDH ) activities with EC 50 values of 512.42 and 500.16 μM, respectively [1]. Uses: Scientific research. Group: Natural products. CAS No. 514-07-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N1177. | |
| Tarcocimab | Tarcocimab (OG1953) is a humanized anti- VEGFA monoclonal antibody (IgG1 type). Tarcocimab is available for research in retinal vein occlusion (RVO) and wet age-related macular degeneration (AMD). Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: OG1953. CAS No. 2408661-40-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99576. | |
| Tarenflurbil | Tarenflurbil ((R)-Flurbiprofen) is the R-enantiomer of the racemate NSAID Flurbiprofen, Tarenflurbil ((R)-Flurbiprofen) inhibits the binding of [ 3 H]9-cis-RA to RXRα LBD with IC 50 of 75 μM. Tarenflurbil can be used for Alzheimer's disease research. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (R)-Flurbiprofen; MPC7869. CAS No. 51543-40-9. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-10291. | |
| Tarextumab | Tarextumab (OMP-59R5) is an anti- Notch2/3 fully human IgG2 monoclonal antibody. Tarextumab shows anti-tumor activity [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: OMP 59R5; Anti-Human NOTCH2 Recombinant Antibody. CAS No. 1359940-55-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99320. | |
| Taribavirin hydrochloride | Taribavirin hydrochloride is an orally active inosine monophosphate dehydrogenase inhibitor, has activity against a wide range of viruses, especially the hepatitis C virus and influenza virus. Taribavirin hydrochloride is a Ribavirin proagent, is designed to concentrate within the liver to target HCV-infected hepatocytes while minimizing distribution within red blood cells (RBCs) and the development of hemolytic anemia [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 40372-00-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10545A. | |
| Tarlatamab | Tarlatamab (AMG-757) is a bispecific T-cell engager (BiTE) antibody targeting delta-like ligand 3 (DLL3). DLL3 is a target that is selectively expressed in small-cell lung cancer (SCLC) tumors, but with minimal normal tissue expression. Tarlatamab has the K D s of 0.64 nM and 0.50 nM for human and nonhuman primate (NHP) DLL3, respectively. Tarlatamab has the K D s of 14.9 nM and 12 nM for human and NHP CD3, respectively. Tarlatamab is a first-in-class HLE BiTE immuno-oncology therapy targeting DLL3 and has the potential for SCLC research [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: AMG-757. CAS No. 2307488-83-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99575. | |
| Tarloxotinib bromide | Tarloxotinib bromide (TH-4000) is an irreversible EGFR/HER2 inhibitor. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TH-4000. CAS No. 1636180-98-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17632. | |
| Tartrazine | Tartrazine (Acid Yellow 23; FD&C Yellow No. 5) is an orally active azo acid dye, orange-yellow powder, soluble in water and turns yellow. Tartrazine is mainly used as a synthetic lemon yellow azo dye for food coloring. Tartrazine is the most stable colorant.Tartrazine induces mitochondria-mediated Apoptosis. Tartrazine can cause neurodevelopmental toxicity, cytotoxicity, and genotoxicity [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [11]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Acid Yellow 23; FD&C Yellow No. 5. CAS No. 1934-21-0. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-D0257. | |
| TAS-119 | TAS-119 is a potent, selective and orally active Aurora A inhibitor with an IC 50 of 1.0 nM. TAS-119 shows high selectivity for Aurora A over other protein kinases, including Aurora B ( IC 50 of 95 nM). TAS-119 has potent antitumor activites [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1453099-83-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137377. | |
| TAS4464 | TAS4464 is a highly potent and selective inhibitor of NEDD8 activating enzyme (NAE) , with an IC 50 of 0.955 nM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1848959-10-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-128586. | |
| TAS4464 hydrochloride | TAS4464 (hydrochloride) is a highly potent and selective inhibitor of NEDD8 activating enzyme (NAE) , with an IC 50 of 0.955 nM [1]. TAS4464 (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1848959-11-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128586A. | |
| Taselisib | Taselisib (GDC-0032) is a potent PI3K inhibitor targets PIK3CA mutations, with K i s of 0.12 nM, 0.29 nM, 0.97 nM, and 9.1 nM for PI3Kδ, PI3Kα, PI3Kγ and PI3Kβ, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GDC-0032; RG-7604. CAS No. 1282512-48-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-13898. | |
| Tasimelteon | Tasimelteon (BMS-214778) is an orally active and selective dual melatonin receptor agonist (DMRA). Tasimelteon has 2.1-4.4 times greater affinity for the MT2 receptor than for the MT1 receptor. Tasimelteon is a circadian regulator and has the potential for Non-24-Hour Sleep-Wake Disorder (Non-24) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-214778; VEC-162. CAS No. 609799-22-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14803. | |
| Tasipimidine sulfate | Tasipimidine sulfate is an orally active and selective α2A-adrenoceptor agonist with a p EC 50 of 7.57 against human α2A-adrenoceptor. Tasipimidine sulfate can be used for situational anxiety and fear research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1465908-73-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109075A. | |
| Tasosartan | Tasosartan is a long-acting angiotensin II ( AngII ) receptor antagonist. Uses: Scientific research. Group: Signaling pathways. Alternative Names: WAY-ANA 756. CAS No. 145733-36-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-A0250. | |
| Taspine | Taspine is a natural product with anti-inflammatory activity. Taspine suppresses P2X4 receptor activity via PI3K inhibition. Taspine inhibits pro-inflammatory signalling via inhibition of P2X4 receptors in macrophage [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 602-07-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-131502. | |
| Taspoglutide | Taspoglutide is a long-acting glucagon-like peptide 1 ( GLP-1 ) receptor agonist developed for treatment of type 2 diabetes, with an EC 50 value of 0.06 nM. Uses: Scientific research. Group: Peptides. Alternative Names: ITM077; R1583; BIM51077. CAS No. 275371-94-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P0165. | |
| Tasquinimod | Tasquinimod is an oral antiangiogenic agent, which has the potential for castration-resistant prostate cancer treatment. Tasquinimod binds to the regulatory Zn 2+ binding domain of HDAC4 with K d of 10-30 nM. Tasquinimod also is a S100A9 inhibitor [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABR-215050. CAS No. 254964-60-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10528. | |
| TAT-14 | TAT-14 is a 14-mer peptide that acts as Nrf2 activator with an anti-inflammatory effect. TAT-14 has no effect on Nrf2 mRNA expression, but increases Nrf2 protein level due to targeting the Nrf2 binding site on Keap1 [1]. Uses: Scientific research. Group: Peptides. CAS No. 1362661-34-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1328. | |
| TAT-cyclo-CLLFVY | TAT-cyclo-CLLFVY is a cyclic peptide inhibitor of HIF-1 heterodimerization that inhibits hypoxia signaling in cancer cells. TAT-cyclo-CLLFVY disrupts HIF-1α/HIF-1β protein-protein interaction with an IC 50 of 1.3 μM [1]. Uses: Scientific research. Group: Peptides. CAS No. 1446322-66-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1420. | |
| Taurine | Taurine, a sulphur-containing amino acid and an organic osmolyte involved in cell volume regulation, provides a substrate for the formation of bile salts, and plays a role in the modulation of intracellular free calcium concentration. Taurine has the ability to activate autophagy in adipocytes [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: 2-Aminoethanesulfonic acid. CAS No. 107-35-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0351. | |
| Tauro-α-muricholic acid sodium | Tauro-α-muricholic acid (T-α-MCA) sodium is a FXR ( Farnesoid X receptor ) antagonist ( IC 50 =28μM). Tauro-α-muricholic acid sodium is also a endogenous metabolite that can be found in cecal [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: T-α-MCA sodium. CAS No. 2260905-08-4. Pack Sizes: 1 mg. Product ID: HY-133890A. | |
| Tauro-β-muricholic acid sodium | Tauro-β-muricholic Acid sodium (T-βMCA sodium), a endogenous metabolite, is a competitive and reversible farnesoid X receptor (FXR) antagonist, with an IC 50 of 40 μM [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: T-βMCA sodium. CAS No. 145022-92-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135103. | |
| Taurochenodeoxycholic acid | Taurochenodeoxycholic acid (12-Deoxycholyltaurine) is one of the main bioactive substances of animals' bile acid. Taurochenodeoxycholic acid induces apoptosis and shows obvious anti-inflammatory and immune regulation properties [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: 12-Deoxycholyltaurine. CAS No. 516-35-8. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-N2027. | |
| Taurochenodeoxycholic acid sodium | Taurochenodeoxycholic acid (12-Deoxycholyltaurine) sodium is one of the main bioactive substances of animals' bile acid. Taurochenodeoxycholic acid sodium induces apoptosis and shows obvious anti-inflammatory and immune regulation properties [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: 12-Deoxycholyltaurine sodium. CAS No. 6009-98-9. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-N1429. | |
| Taurochenodeoxycholic acid (sodium) (Standard) | Taurochenodeoxycholic acid (sodium) (Standard) is the analytical standard of Taurochenodeoxycholic acid (sodium). This product is intended for research and analytical applications. Taurochenodeoxycholic acid (12-Deoxycholyltaurine) sodium is one of the main bioactive substances of animals' bile acid. Taurochenodeoxycholic acid sodium induces apoptosis and shows obvious anti-inflammatory and immune regulation properties [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 6009-98-9. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N1429R. | |
| Taurocholic acid | Taurocholic acid (N-Choloyltaurine) has marked bioactive effects such as an inhibitory potential against hepatic artery ligation induced biliary damage by upregulation of VEGF-A expression. Taurocholic acid has immunoregulation effect [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Taurocholic Acid. CAS No. 81-24-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1788. | |
| Taurocholic acid-d4 | Taurocholic acid-d 4 is deuterium labeled Taurocholic acid. Taurocholic acid (N-Choloyltaurine) is a bile acid involved in the emulsification of fats. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: N-Choloyltaurine-d4. CAS No. 252030-90-3. Pack Sizes: 100 μg (192.41 μM * 1 mL in Methanol); 1 mg; 5 mg. Product ID: HY-B1788S1. | |
| Taurocholic acid-d4 sodium | Taurocholic acid-d 4 (sodium) is the deuterium labeled Taurocholic acid. Taurocholic acid (N-Choloyltaurine) is a bile acid involved in the emulsification of fats. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: N-Choloyltaurine-d4 sodium. CAS No. 2410279-93-3. Pack Sizes: 500 μg; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-B1788S. | |
| Taurocholic acid sodium | Taurocholic acid sodium (Sodium taurocholate) has marked bioactive effects such as an inhibitory potential against hepatic artery ligation induced biliary damage by upregulation of VEGF-A expression. Taurocholic acid sodium has immunoregulation effect [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Sodium taurocholate; N-Choloyltaurine sodium. CAS No. 145-42-6. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-N0545. | |
| Taurocholic acid sodium salt hydrate | Taurocholic acid sodium salt hydrate (Sodium taurocholate hydrate) is a bile acid involved in the emulsification of fats. Uses: Scientific research. Group: Natural products. Alternative Names: Sodium taurocholate hydrate; N-Choloyltaurine sodium salt hydrate. CAS No. 345909-26-4. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-B1131. | |
| Taurodeoxycholate sodium salt | Taurodeoxycholate sodium salt is a bile salt-related anionic detergent. Taurodeoxycholate sodium salt is formed in the liver by conjugation of deoxycholate with Taurine (HY-B0351). Taurodeoxycholate sodium salt is used for isolation of membrane proteins including inner mitochondrial membrane proteins. Taurodeoxycholate (TDCA) exhibits anti-inflammatory and neuroprotective effects [1] [2] [3] [9] [10]. Uses: Scientific research. Group: Natural products. CAS No. 1180-95-6. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-128853. | |
Would you like to list your products on USA Chemical Suppliers?
Our database is helping our users find suppliers everyday.