MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Tolterodine-d14 hydrochloride | Tolterodine-d 14 (hydrochloride) is the deuterium labeled Tolterodine hydrochloride[1]. Tolterodine hydrochloride is a potent muscarinic receptor antagonist[2][3]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: (R)-(+)-Tolterodine-d14 hydrochloride; (+)-Tolterodine-d14 hydrochloride; (R)-Tolterodine-d14 hydrochloride; PNU-200583-d14 hydrochloride. CAS No. 1217645-16-3. Pack Sizes: 1 mg. Product ID: HY-A0024S. |  |
| Tolterodine tartrate | Tolterodine Tartrate (Kabi-2234; PNU-200583E) is a potent muscarinic receptor antagonist and shows selectivity for the urinary bladder over salivary glands in vivo. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Kabi-2234; PNU-200583E. CAS No. 124937-52-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-90010. | |
| Toltrazuril | Toltrazuril (BAY-i 9142) is an antiprotozoal agent that acts upon Coccidia parasites. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY-i 9142. CAS No. 69004-03-1. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0175. | |
| Tolvaptan | Tolvaptan is a selective, competitive and orally active vasopressin receptor 2 ( V 2 R ) antagonist with an IC 50 of 1.28 μM for the inhibition of arginine vasopressin (AVP)-induced platelet aggregation. Tolvaptan induces cell apoposis and affects cell cycle. Tolvaptan can be used for the research of hyponatremia [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: OPC-41061. CAS No. 150683-30-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-17000. | |
| Tomaralimab | Tomaralimab (OPN-305) is a humanised anti-TLR2 IgG4 monoclonal antibody. Tomaralimab has the potential for the research of Myelodysplastic Syndromes (MDS) [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: OPN-305. CAS No. 1449294-76-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99555. | |
| Tomatidine | Tomatidine acts as an anti-inflammatory agent by blocking NF-κB and JNK signaling [1]. Tomatidine activates autophagy either in mammal cells or C elegans [2]. Uses: Scientific research. Group: Natural products. CAS No. 77-59-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N2149. | |
| Tomatidine hydrochloride | Tomatidine hydrochloride acts as an anti-inflammatory agent by blocking NF-κB and JNK signaling [1]. Tomatidine hydrochloride activates autophagy either in mammal cells or C elegans [2]. Uses: Scientific research. Group: Natural products. CAS No. 6192-62-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N2149A. | |
| Tomatine | Tomatine is a glycoalkaloid, found in the tomato plant ( Lycopersicon esculentum Mill.). Tomatine elicits neurotoxicity in RIP1 kinase and caspase-independent manner. Tomatine promotes the upregulation of nuclear apoptosis inducing factor (AIF) in neuroblastoma cells. Tomatine also inhibits 20S proteasome activity [1]. Uses: Scientific research. Group: Natural products. Alternative Names: α-Tomatine; Lycopersicin; Tomatin. CAS No. 17406-45-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 20 mg. Product ID: HY-N2166. | |
| Tomivosertib | Tomivosertib (eFT508) is a potent, highly selective, and orally active MNK1 and MNK2 inhibitor, with IC 50 s of 1-2 nM against both isoforms. Tomivosertib (eFT508) treatment leads to a dose-dependent reduction in eIF4E phosphorylation at serine 209 (IC 50 =2-16 nM) in tumor cell lines [1]. Tomivosertib (eFT508) also dramatically downregulates PD-L1 protein abundance [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: eFT508. CAS No. 1849590-01-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100022. | |
| Tonabersat | Tonabersat (SB-220453) is a gap-junction modulator. Tonabersat prevents inflammatory damage in the central nervous system [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SB-220453. CAS No. 175013-84-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15204. | |
| Toosendanin | Toosendanin, a triterpenoid extracted from the bark of fruit of Melia toosendan Sieb. et Zucc., possesses analgesic, insecticidal and anti-inflammatory activities [1]. Uses: Scientific research. Group: Natural products. CAS No. 58812-37-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0263. | |
| Topiramate | Topiramate (McN 4853) is a broad-spectrum antiepileptic agent. Topiramate is a GluR5 receptor antagonist. Topiramate produces its antiepileptic effects through enhancement of GABAergic activity, inhibition of kainate/AMPA receptors, inhibition of voltage-sensitive sodium and calcium channels , increases in potassium conductance, and inhibition of carbonic anhydrase [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: McN 4853; RWJ 17021. CAS No. 97240-79-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0122. | |
| Topiroxostat | Topiroxostat (FYX-051) is a potent and orally active xanthine oxidoreductase (XOR) inhibitor with an IC 50 value of 5.3 nM and a K i value of 5.7 nM. Topiroxostat exhibits weak CYP3A4 -inhibitory activity (18.6%). Topiroxostat has the potential for hyperuricemia treatment [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FYX-051. CAS No. 577778-58-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14874. | |
| Topoisomerase II inhibitor 14 | Topoisomerase II inhibitor 14 (compound 2f) is a potent inhibtor of Topoisomerase II, with anticancer activity. Topoisomerase II inhibitor 14 induces apoptosis, and arrests cell cycle at S phase. Topoisomerase II inhibitor 14 exhibits antioxidant effect and decreases the level of GSH, MDA, and NO [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 305343-00-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-W278582. | |
| Topotecan | Topotecan (SKF 104864A; NSC 609669) is an orally active and potent Topoisomerase I inhibitor. Topotecan induces cell cycle arrest in G0/G1 and S phases and promotes apoptosis. Topotecan shows anticancer activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SKF 104864A; NSC 609669. CAS No. 123948-87-8. Pack Sizes: 1 mg. Product ID: HY-13768. | |
| Topotecan hydrochloride | Topotecan Hydrochloride (SKF 104864A Hydrochloride) is a Topoisomerase I inhibitor with potent antineoplastic activities. Uses: Scientific research. Group: Natural products. Alternative Names: SKF 104864A hydrochloride; NSC 609669 hydrochloride. CAS No. 119413-54-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13768A. | |
| TO-PRO-3 iodide | TO-PRO-3 iodide is a highly efficient blue fluorescent dye that can stain cytoplasm as a cell tracer. Uses: Scientific research. Group: Fluorescent dye. CAS No. 157199-63-8. Pack Sizes: 671 μg (5 mM * 200 μL in DMSO). Product ID: HY-117070. | |
| TOPS | TOPS is a highly water-soluble aniline derivative widely used in diagnostics and biological experiments. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 40567-80-4. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-15933. | |
| Torcetrapib | Torcetrapib (CP-529414) is a selective, potent cholesteryl ester transfer protein ( CETP ) inhibitor. A typical inhibition curve for whole human plasma, having a CETP concentration of 37 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CP-529414. CAS No. 262352-17-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-12089. | |
| Toreforant | Toreforant is a potent and selective histamine H 4 receptor ( H4R ) antagonist, with a K i at the human receptor of 8.4 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: JNJ-38518168. CAS No. 952494-46-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16756. | |
| Toremifene | Toremifene (Z-Toremifene) is a second-generation selective estrogen-receptor modulator (SERM) in development for the prevention of osteoporosis. Toremifene also potent inhibits infectious EBOV Zaire and Marburg (MARV) with IC 50 of 0.07 μM and 2.6 μM, respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Z-Toremifene; NK 622 free base; FC-1157a free base. CAS No. 89778-26-7. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg. Product ID: HY-B0005A. | |
| Toremifene citrate | Toremifene citrate (Z-Toremifene citrate) is a second-generation selective estrogen-receptor modulator (SERM) in development for the prevention of osteoporosis. Toremifene citrate also potent inhibits infectious EBOV Zaire and Marburg (MARV) with IC 50 of 0.07 μM and 2.6 μM, respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Z-Toremifene citrate; NK 622; FC-1157a. CAS No. 89778-27-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0005. | |
| Torin 1 | Torin 1 is a potent inhibitor of mTOR with an IC 50 of 3 nM. Torin 1 inhibits both mTORC1 / 2 complexes with IC 50 values between 2 and 10 nM. Torin 1 is an effective inducer of autophagy. Uses: Scientific research. Group: Signaling pathways. CAS No. 1222998-36-8. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13003. | |
| Toripalimab | Toripalimab is the first domestic anti-tumor PD-1 antibody in China. Toripalimab is a selective, recombinant, humanized monoclonal antibody against PD-1. Toripalimab is able to bind to PD-1 and block the interaction with its ligands. Toripalimab has exhibited primary anti-tumor effects in tumors such as melanoma, lung cancer, digestive tract tumors, hepatobiliary and pancreatic tumors, neuroendocrine neoplasms, nasopharyngeal carcinoma and urothelial carcinoma [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1924598-82-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P9978. | |
| Torsemide | Torsemide (Torasemide) is an orally active loop diuretic. Torsemide has anti-aldosterone and vasodilatory effects. Torsemide also can be used for the research of heart failure, renal disease and hepatic cirrhosis [1] [1] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Torasemide. CAS No. 56211-40-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 100 mg. Product ID: HY-B0247. | |
| Torudokimab | Torudokimab is a humanized antibody expressed in CHO, targeting IL-33. Torudokimab has a huIgG4SP type heavy chain and a huκ type light chain, with a predicted molecular weight (MW) of 145.22 kDa. The isotype control for Torudokimab can refer to Human IgG4 kappa, Isotype Control (HY-P99003). Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2241728-76-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990669. | |
| Tosedostat | Tosedostat (CHR-2797) is an orally active aminopeptidase inhibitor. CHR-2797 exerts antiproliferative effects against a range of tumor cell lines [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CHR-2797. CAS No. 238750-77-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14807. | |
| Tositumomab | Tositumomab is a murine IgG2a lambda monoclonal antibody directed against the CD20 antigen, which is found on the surface of normal and malignant B lymphocytes [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-Human CD20 Recombinant Antibody. CAS No. 192391-48-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99326. | |
| Tos-PEG3 | Tos-PEG3 is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Tos-PEG3 (structure 1) can be used for the synthesis of 3'-aminooxy oligonucleotides solid supports [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 77544-68-4. Pack Sizes: 1 g; 5 g; 10 g; 25 g. Product ID: HY-23408. | |
| Tos-PEG3-CH2COOtBu | Tos-PEG3-CH2COOtBu is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1530778-24-5. Pack Sizes: 100 mg; 1 g; 5 g; 10 g. Product ID: HY-45018. | |
| Tosufloxacin tosylate hydrate | Tosufloxacin tosylate hydrate (A-61827) is an orally active fluoroquinolone antibiotic. Tosufloxacin shows a broad spectrum of antibacterial activity against gram-positive and gram-negative bacteria [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: A-61827 tosylate hydrate; T-3262. CAS No. 1400591-39-0. Pack Sizes: 10 mM * 1 mL; 200 mg; 1 g; 5 g; 10 g. Product ID: HY-B1802A. | |
| (+)-Totarol | (+)-Totarol is a diterpenoid compound isolated from Podocarpus spp. (+)-Totarol is a potent antioxidant and antibacterial agent [1]. Uses: Scientific research. Group: Natural products. CAS No. 511-15-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N1136. | |
| Tovorafenib | Tovorafenib (TAK-580, MLN 2480) is an orally active and selective inhibitor of pan-Raf kinase. Tovorafenib can be used for the study of glioma [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TAK-580; MLN 2480; BIIB-024. CAS No. 1096708-71-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15246. | |
| Toxoflavin | Toxoflavin (Xanthothricin) is an antagonist of transcription factor 4 (TCF4)/β-catenin complex , also acts as an inhibitor of KDM4A , with antitumor and antibiotic activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Xanthothricin; Toxoflavine; PKF-118-310. CAS No. 84-82-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-100760. | |
| Tozadenant | Tozadenant is an adenosine A 2A receptor antagonist, with K i of 11.5 nM on human A 2A and 6 nM on rhesus A 2A. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SYN115. CAS No. 870070-55-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10995. | |
| Tozasertib | Tozasertib (VX 680; MK-0457) is an inhibitor of Aurora A/B/C kinases with K i s of 0.6, 18, 4.6 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: VX 680; MK-0457. CAS No. 639089-54-6. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 250 mg. Product ID: HY-10161. | |
| Tozorakimab | Tozorakimab (MEDI-3506) is a human immunoglobulin G1 monoclonal antibody targeting interleukin-33. Tozorakimab reduces inflammation and epithelial dysfunction. Tozorakimab can be used to research chronic obstructive pulmonary disease [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MEDI-3506. CAS No. 2376858-66-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99550. | |
| TP-020 | TP-020 (MGAT2-IN-1) is an orally active inhibitor of monoacylglycerol acyltransferase (MGAT2) with IC 50 of 7.8 and 2.4 nM for human and mouse MGAT2, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MGAT2-IN-1. CAS No. 1800025-30-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101857. | |
| TP-021 | TP-021 (BCL6-IN-8c) is a potent and orally active B-cell lymphoma 6 (BCL6)-corepressor interaction inhibitor with an IC 50 of 0.10 μM in cell-free enzyme-linked immunosorbent assay [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BCL6-IN-8c. CAS No. 2130878-25-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119402. | |
| TP-024 | TP-024 (FTBMT) is a selective GPR52 agonist with an EC 50 of 75 nM [1]. TP-024 has antipsychotic and procognitive properties [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FTBMT. CAS No. 1358575-02-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101787. | |
| TP-040 | TP-040 (O-GlcNAcase-IN-1) is a potent and novel OGA inhibitor with an IC 50 value of 46 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: O-GlcNAcase-IN-1. CAS No. 2757254-99-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-131979. | |
| TP0427736 hydrochloride | TP0427736 hydrochloride is a potent inhibitor of ALK5 kinase activity with an IC 50 of 2.72 nM and this effect is 300-fold higher than the inhibitory effect on ALK3 (IC 50 =836 nM). TP0427736 hydrochloride also inhibits Smad2/3 phosphorylation in A549 cells induced by TGF-β1 with an IC 50 value of 8.68 nM. TP0427736 hydrochloride can be used for the research of androgenic alopecia (AGA) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2459963-17-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-118528A. | |
| TP0463518 | TP0463518 is a potent hypoxia-inducible factor prolyl hydroxylases ( PHD s) inhibitor with a K i value of 5.3 nM for human PHD2. TP0463518 also inhibits human PHD1 / PHD3 with IC 50 s of 18 and 63 nM as well as monkey PHD2 with an IC 50 value of 22 nM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1558021-37-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112144. | |
| TP-060 | Glucosylceramide synthase-IN-1 (T-036) a potent, brain-penetrant and orally active glucosylceramide synthase (GCS) inhibitor with IC 50 s of 31 nM and 51 nM for human GCS and mouse GCS, respectively. Glucosylceramide synthase-IN-1 can be used for Gaucher's disease research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Glucosylceramide synthase-IN-1. CAS No. 2601393-20-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144266. | |
| TP-064 | TP-064 is a potent and selective proteinarginine methyltransferase 4 (PRMT4; CARM1) inhibitor ( IC 50 <10 nM). TP-064 inhibits dimethylation of BAF155 ( IC 50 of 340 nM) and MED12 ( IC 50 of 43 nM). TP-064 is inactive against the other family members except for PRMT6 (IC 50 of 1.3 μM). TP-064 has anticancer activities [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2080306-20-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-114965. | |
| TP-1287 | TP-1287, a prodrug of Alvocidib (HY-10005), is an orally active CDK9 inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2044686-42-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153260. | |
| TP-238 hydrochloride | TP-238 hydrochloride is a potent and selective dual CECR2/BPTF probe with IC 50 values of 30 nM and 350 nM, respectively. TP-238 hydrochloride also inhibits BRD9 with a pIC 50 of 5.9 and is less active against other 338 kinases [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2415263-05-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114205A. | |
| TP-3654 | TP-3654 is a second-generation Pim kinase inhibitor with K i values of 5 and 42 nM for Pim-1 and Pim-3, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1361951-15-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101126. | |
| TP-5801 | TP-5801 is an orally active TNK1 ( non-receptor tyrosine kinase ) inhibitor ( IC 50 =1.40 nM), and shows anti-tumor activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2574474-81-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-147316. | |
| TP-808 | TP-808 is an intermediate used in tetracycline antibiotic synthesis with antimicrobial activity. TP-808 binds to the 30S ribosome subunit of the bacteria, preventing aminoacyl-trNA from entering the A site, thereby inhibiting the extension of the protein chain. TP-808 can be used in antibiotic drug development research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 852821-06-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13952. | |
| TPBM | TPBM is a potent estrogen receptor α (ERα) inhibitor with an IC 50 value of 9 μM for 17β-estradiol (E2)-ER&alpha. TPBM reduces E2·ERα recruitment to an endogenous estrogen-responsive gene. TPBM inhibits E2-dependent growth of ERα-positive cancer cells (IC 50 =5 μM). TPBM is not toxic to cells and does not affect estrogen-independent cell growth [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 6466-43-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-131404. | |
| TPI-287 | TPI-287, a blood-brain barrier-permeable microtubule stabilizer, can significantly reduce metastatic colonization of breast cancer in the brain [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 849213-15-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-126899. | |
| TPMPA | TPMPA, a hybrid of isoguvacine and 3-APMPA, is the first selective antagonist for a GABA C receptor ( K B = 2.1 μM), but not to interact with GABA A ( K B = 320 μM) or GABA B receptors ( EC 50 = 500 μM). TPMPA has the potential for the research of suppressing orientation selectivity in ganglion cells [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 182485-36-5. Pack Sizes: 10 mg. Product ID: HY-101359. | |
| TPP-1 | TPP-1 is a potent inhibitor of the PD-1/PD-L1 interaction. TPP-1 binds specifically to PD-L1 with a high affinity ( K D =95 nM). TPP-1 inhibits human tumor growth in vivo via reactivating T-cell function [1]. Uses: Scientific research. Group: Peptides. CAS No. 2426685-25-6. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P3139. | |
| TPPS | TPPS can be used as a non-cytotoxic probe for detecting tumor location [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 35218-75-8. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-W075353. | |
| TPT-260 Dihydrochloride | TPT-260 Dihydrochloride (NSC55712) is a thiourea derivative. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NSC55712; TPU-260 Dihydrochloride. CAS No. 2076-91-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13769A. | |
| TQS | TQS is a α7 nicotinic acetylcholine receptor ( nAChR ) positive allosteric modulator. TQS can be used for the research of neuroinflammatory pain [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 353483-92-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107682. | |
| TR-100 | TR-100 is a small molecule inhibitor of tumor-associated troponin ( Tpm ). TR-100 affects the interaction of Tpm3.1 with actin filaments by binding to the C-terminal of Tpm3.1 , thereby affecting the stability and function of the actin filaments. This mechanism of action allows TR-100 to specifically affect actin filaments in cancer cells without compromising heart muscle function. TR-100 can be used to study the role of Tpm3.1 in cancer cell proliferation and survival and the effects of Tpm3.1 on insulin-stimulated glucose uptake and insulin secretion [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1128165-86-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-124689. | |
| Trabodenoson | Trabodenoson (INO-8875), an adenosine mimetic, is a highly selective Adenosine A1 receptor agonist. Trabodenoson (INO-8875) is used in the study for Primary Open-Angle Glaucoma [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: INO-8875. CAS No. 871108-05-3. Pack Sizes: 10 mM * 1 mL; 5 mg. Product ID: HY-106007. | |
| Tracazolate hydrochloride | Tracazolate (ICI 136753) hydrochloride is a potent GABA A receptor modulator. Tracazolate hydrochloride has selectivity for β3 and potentiates α1β1γ2s (EC 50 =13.2 μM), α1β3γ2 (EC 50 =1.5 μM). Tracazolate hydrochloride has the potency (EC 50 ) determined by the nature of the third subunit (γ1-3, δ, ε) within the receptor complex. Tracazolate hydrochloride possesses anxiolytic and anticonvulsant activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ICI 136753 hydrochloride. CAS No. 1135210-68-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-B1803A. | |
| Tradipitant | Tradipitant (VLY-686) is a neurokinin-1 ( NK-1 ) antagonist. Uses: Scientific research. Group: Signaling pathways. Alternative Names: VLY-686; LY686017. CAS No. 622370-35-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-16732. | |
| Tragacanth gum | Tragacanth gum is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 9000-65-1. Pack Sizes: 5 g; 10 g; 25 g; 50 g. Product ID: HY-W250121. | |
| Tralokinumab | Tralokinumab, a fully human IgG4 monoclonal antibody, specifically binds with high affinity to IL-13 alone, preventing its interaction with the receptor and subsequent downstream signalling. Tralokinumab can be used for the research of the atopic dermatitis (AD) [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1044515-88-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99053. | |
| TRAM-39 | TRAM-39 is a selective blocker of intermediate conductance Ca 2+ -activated K + ( IK Ca ) channels. TRAM-39 inhibits KCa3.1 channel with an IC 50 value of 60 nM. TRAM-39 can be used for the research of ataxia, epilepsy, memory disorders, schizophrenia and Parkinsons disease [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 197525-99-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103308. | |
| Trametinib | Trametinib (GSK1120212; JTP-74057) is an orally active MEK inhibitor that inhibits MEK1 and MEK2 with IC 50 s of about 2 nM. Trametinib activates autophagy and induces apoptosis [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GSK1120212; JTP-74057. CAS No. 871700-17-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-10999. | |
| Trametinib (Standard) | Trametinib (Standard) is the analytical standard of Trametinib. This product is intended for research and analytical applications. Trametinib (GSK1120212; JTP-74057) is an orally active MEK inhibitor that inhibits MEK1 and MEK2 with IC 50 s of about 2 nM. Trametinib activates autophagy and induces apoptosis [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 871700-17-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10999R. | |
| Tramiprosate | Tramiprosate (Homotaurine), an orally active and brain-penetrant natural amino acid found in various species of red marine algae. Tramiprosate binds to soluble Aβ and maintains Aβ in a non-fibrillar form. Tramiprosate is also a GABA analog and possess neuroprotection, anticonvulsion and antihypertension effects [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Homotaurine; 3-Amino-1-propanesulfonic acid. CAS No. 3687-18-1. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-14602. | |
| Trandolapril | Trandolapril (RU44570) is a nonsulfhydryl proagent that is hydrolysed to the active diacid Trandolaprilat. Trandolapril is an orally administered angiotensin converting enzyme ( ACE ) inhibitor that has been used in the treatment of hypertension and congestive heart failure (CHF), and after myocardial infarction (MI) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RU44570. CAS No. 87679-37-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0592. | |
| Trandolaprilate hydrate | Trandolaprilate hydrate is a potent angiotensin-converting enzyme ( ACE ) inhibitor. Trandolaprilate hydrate partially inhibits angiotensin-I-mediated c-fos induction. Trandolaprilate is main bioactive metabolite of Trandolapril. Trandolaprilate shows high lipophilicity [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Trandolaprilat hydrate; RU 44403 hydrate. CAS No. 951393-55-8. Pack Sizes: 1 mg. Product ID: HY-A0116A. | |
| Tranexamic acid | Tranexamic acid (cyclocapron), a cyclic analog of lysine, is an orally active antifibrinolytic agent. Tranexamic acid attenuates the effects of severe trauma, inhibits urokinase plasminogen activator and ameliorates dry wrinkles. Tranexamic acid can used for the research of hemostasis [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: cyclocapron. CAS No. 1197-18-8. Pack Sizes: 10 mM * 1 mL; 500 mg; 5 g; 10 g. Product ID: HY-B0149. | |
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