MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Protirelin acetate | Protirelin Acetate is a highly conserved neuropeptide that exerts the hormonal control of thyroid-stimulating hormone (TSH) levels as well as neuromodulatory functions. Uses: Scientific research. Group: Peptides. Alternative Names: Thyrotropin-releasing-hormone acetate; TRH acetate. CAS No. 120876-23-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-P0002A. |  |
| PROTO-1 | PROTO-1 is a hair cell protector and can be used in studies of ototoxicity-induced hair cell death [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 312951-85-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18673. | |
| Protoapigenone | Protoapigenone is an antineoplastic agent isolated from ferns. Protoapigenone has significant inhibitory activity against Hep G2, Hep 3B, MCF-7, A549 and MDAMB-231, with IC 50 s values of 1.60, 0.23, 0.78, 3.88 and 0.27 μg/mL respectively [1]. Uses: Scientific research. Group: Natural products. CAS No. 862884-32-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-134008. | |
| Protocatechualdehyde | Protocatechualdehyde (Catechaldehyde), a natural polyphenol compound isolated from the roots of radix Salviae Miltiorrhizae , is associated with a wide variety of biological activities and has been widely used in medicine as an antioxidant, anti-aging, an antibacterial and anti-inflammatory agent [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Catechaldehyde; Protocatechuic aldehyde; Rancinamycin IV. CAS No. 139-85-5. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-N0295. | |
| Protocatechuate 3,4-dioxygenase | Protocatechuate 3,4-dioxygenase is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Signaling pathways. CAS No. 9029-47-4. Pack Sizes: 25 U. Product ID: HY-P2915. | |
| Protocatechuic acid | Protocatechuic acid is a phenolic compound which exhibits neuroprotective effect. Uses: Scientific research. Group: Natural products. Alternative Names: 3,4-Dihydroxybenzoic acid. CAS No. 99-50-3. Pack Sizes: 10 mM * 1 mL; 200 mg; 1 g. Product ID: HY-N0294. | |
| Protocatechuic acid (Standard) | Protocatechuic acid (Standard) is the analytical standard of Protocatechuic acid. This product is intended for research and analytical applications. Protocatechuic acid is a phenolic compound which exhibits neuroprotective effect. Uses: Scientific research. Group: Natural products. CAS No. 99-50-3. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0294R. | |
| Protodioscin | Protodioscin, a major steroidal saponin in Trigonella foenum-graecum Linn., has been shown to exhibit multiple biological actions, such as anti-hyperlipidemia, anti-cancer, sexual effects and cardiovascular properties. Uses: Scientific research. Group: Natural products. CAS No. 55056-80-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0799. | |
| Protopine | Protopine (Corydinine), an isoquinoline alkaloid, is a specific reversible and competitive inhibitor of acetylcholinesterase. Protopine exhibits anti-inflammation, anti-microbial, anti-angiogenic and anti-tumour activity [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Corydinine. CAS No. 130-86-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0793. | |
| Protoporphyrin IX | Protoporphyrin IX is a final intermediate in the heme biosynthetic pathway, which acts as a radiation sensitizer enhancing ROS generation even in a hypoxic state and inducing DNA damage. Protoporphyrin IX also acts as a photo sensitizer undergoing photobleaching that occurs through direct degradation by light irradiation. Protoporphyrin IX is formed and accumulated following 5-aminolevulinic acid (5-ALA) (HY-W000450) administration in the tumor cells of rats. Protoporphyrin IX causes selective improvement of basal cell carcinoma when activated red fluorescence of a peak wavelength at 405 nm. Protoporphyrin IX is promising for research of sonodynamic and photodynamic agents for a wide range of cancers, such as bladder cancer and nodular basal cell carcinoma [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. CAS No. 553-12-8. Pack Sizes: 100 mg; 250 mg. Product ID: HY-B1247. | |
| (+)-proto-Quercitol | (+)-proto-Quercitol is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Quercitol. CAS No. 488-73-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-W145689. | |
| Protriptyline hydrochloride | Protriptyline hydrochloride is a tricyclic antidepressant (TCA), specifically a secondary amine, for the treatment of depression and ADHD. Uses: Scientific research. Group: Signaling pathways. CAS No. 1225-55-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-B0949. | |
| Pro-xylane (30% in water) | Pro-xylane (30% in water) (Hydroxypropyl tetrahydropyrantriol) is a biologically active C-glycoside in aqueous media, acts as an activator of glycosaminoglycans (GAGs) biosynthesis. Pro-xylane (30% in water) has potential skin anti-aging properties and is eco-friendly, biodegradable, and can be used in cosmetic research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Hydroxypropyl tetrahydropyrantriol. CAS No. 439685-79-7. Pack Sizes: 50 mg (1.56 M * 166.67 μL in Water); 100 mg (1.56 M * 333.33 μL in Water). Product ID: HY-108036. | |
| Proxyphylline | Proxyphylline is a methylxanthine derivative used as a cardiac stimulant, vasodilator and bronchodilator [1]. Uses: Scientific research. Group: Natural products. CAS No. 603-00-9. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-B1742. | |
| PRT062607 | PRT062607(P505-15; PRT-2607; BIIB-057) is a highly specific and potent inhibitor of Syk with IC50 of 1-2 nM; >80-fold selective for Syk than Fgr, Lyn, FAK, Pyk2 and Zap70. Uses: Scientific research. Group: Signaling pathways. Alternative Names: P505-15; PRT-2607; BIIB-057. CAS No. 1370261-96-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15322. | |
| PRT062607 Hydrochloride | PRT062607 (P505-15) Hydrochloride is an orally available Syk inhibitor (IC50: 1 nM) that inhibits inflammation and induction Apoptosis. PRT062607 Hydrochloride exerts potent antitumor activity in tumor xenograft mouse models[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: P505-15 Hydrochloride. CAS No. 1370261-97-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15323. | |
| PRT4165 | PRT4165 is a potent inhibitor of polycomb-repressive complex 1 (PRC1)-mediated H2A ubiquitylation. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NSC600157. CAS No. 31083-55-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-19817. | |
| Prucalopride | Prucalopride is an orally active, selective and specific 5-HT 4 receptor agonist (high affinity), with pK i s of 8.6 and 8.1 for human 5-HT4a/4b receptors , respectively. Prucalopride improves intestinal motility by promoting regeneration of the intestinal nervous system in rats. Prucalopride also shows anticancer activity by blocking of the PI3K/AKT/mTor signaling pathway. Prucalopride can be used in studies of chronic constipation, pseudo-intestinal obstruction and cancer [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 179474-81-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14151. | |
| Prucalopride succinate | Prucalopride succinate is an orally active, selective and specific 5-HT 4 receptor agonist (high affinity), with pK i s of 8.6 and 8.1 for human 5-HT4a/4b receptors , respectively. Prucalopride succinate improves intestinal motility by promoting regeneration of the intestinal nervous system in rats. Prucalopride succinate also shows anticancer activity by blocking of the PI3K/AKT/mTor signaling pathway. Prucalopride succinate can be used in studies of chronic constipation, pseudo-intestinal obstruction and cancer [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R-108512. CAS No. 179474-85-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-12694. | |
| Prulifloxacin | Prulifloxacin (NM441) is an orally active fluoroquinolone antibiotic with a broad spectrum of activity against Gram-positive and -negative bacteria. Prulifloxacin is a proagent of a thiazeto-quinoline carboxylic acid derivative Ulifloxacin (NM394). Prulifloxacin has the potential for lower urinary tract infections and exacerbations of chronic bronchitis [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NM441. CAS No. 123447-62-1. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0024. | |
| Prunasin | Prunasin is a inhibitor of DNA Polymerase β [1]. Uses: Scientific research. Group: Natural products. CAS No. 99-18-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N1548. | |
| Prunetin | Prunetin, an O-methylated isoflavone, possesses anti-inflammatory activity. Prunetin is a potent human aldehyde dehydrogenases inhibitor [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 552-59-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N2597. | |
| Prunin | Prunin is a potent inhibitor of human enterovirus A71 (HEVA71). Prunin shows strong inhibitory activity against protein tyrosine phosphatase 1B (PTP1B), with an IC 50 of 5.5 μM [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Naringenin 7-0-glucoside. CAS No. 529-55-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N1549. | |
| Prussian blue insoluble | Prussian blue soluble is a good adsorbent to be used as antidotes for poisoning with cesium or thallium ions. Prussian blue soluble has anticancerous and antibacterial properties. Prussian blue soluble can be used as a contrast agent in photoacoustic and magnetic resonance imaging (MRI) [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Iron(III) ferrocyanide; Milori blue. CAS No. 14038-43-8. Pack Sizes: 100 mg; 500 mg; 1 g. Product ID: HY-106594A. | |
| Pruvanserin | Pruvanserin (EMD 281014 free acid) is a selective 5-HT2A receptor antagonist. Pruvanserin alleviates tactile allodynia in diabetic rats. Pruvanserin can also be used for research of insomnia [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EMD 281014 free acid; LY 2422347. CAS No. 443144-26-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106246. | |
| Pruvonertinib | YK-029A is an orally active inhibitor of mutant EGFR , targeting to both the T790M mutations (EGFR T790M ) and exon 20 insertion of EGFR (EGFRex20ins). YK-029A exhibits significant antitumor activity, and results tumor regression in EGFRex20ins-driven PDX models [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: YK-029A. CAS No. 2064269-82-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-155537. | |
| PRX-07034 hydrochloride | PRX-07034 hydrochloride is a highly selective and potent 5-HT6 receptor antagonist with a K i = 4-8 nM and an IC 50 of 19 nM. PRX-07034 can be used for the research of enhancing working memory and cognitive flexibility [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 903580-39-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14559. | |
| PRX-08066 | PRX-08066 is a selective 5-hydroxytryptamine receptor 2B (5-HT2BR, IC50= 3. Uses: Scientific research. Group: Signaling pathways. CAS No. 866206-54-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15472. | |
| PS10 | PS10 is a novel, potent and ATP-competitive pan- PDK inhibitor, inhibits all PDK isoforms with IC 50 of 0.8 μM, 0.76 μM, 2.1 μM and 21.3 μM for PDK2, PDK4, PDK1, and PDK3, respectively. PS10 shows high affinity for PDK2 ( K d = 239 nM) than for Hsp90 (K d = 47 μM) [1]. PS10 improves glucose tolerance, stimulates myocardial carbohydrate oxidation in diet-induced obesity. PS10 has the potential for the investigation of diabetic cardiomyopathy [2].PDK: pyruvate dehydrogenase kinase. Uses: Scientific research. Group: Signaling pathways. CAS No. 1564265-82-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-121744. | |
| PS-1145 | PS-1145 is an I?B kinase (IKK) inhibitor with an IC50 of 88 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 431898-65-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18008. | |
| PS121912 | PS121912 is a selective vitamin D receptor (VDR)-coregulator inhibitor. PS121912 has acceptable metabolic stability in vivo. PS121912 can be used for the research of cancer[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1529814-60-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103053. | |
| PS210 | PS210 is a potent and selective PDK1 activator with a K d of 3 μM and targets the PIF-binding pocket of PDK1. PS210 is inactive against other protein kinases, including PDK1 downstream signaling components such as S6K, PKB/Akt or GSK3. In cells, the prodrug of PS210 (PS423) acts as a substrate-selective inhibitor of PDK1 , inhibiting the phosphorylation and activation of S6K [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1221962-86-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-121629. | |
| PS423 | PS423 is a prodrug of PS210, acting as a substrate-selective inhibitor of PDK1 , inhibiting the phosphorylation and activation of S6K. PS210 is a potent and selective PDK1 activator targeting the PIF binding pocket of PDK1 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1221964-37-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-124060. | |
| PS47 | PS47 is an inactive E-isomer of PS48. PS48 is an activator of PDK1. PS47 can be used as a negative control for PS48 [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1180676-33-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13851. | |
| PS48 | PS48 is an activator of PDK1 with an AC 50 of 8 μM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1180676-32-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15967. | |
| Psalmotoxin 1 | Psalmotoxin 1 (PcTx1) is a protein toxin that can bind at subunit-subunit interfaces of acid-sensing ion channel 1a (ASIC1a). Psalmotoxin 1 is a potent and slective ASIC1a inhibitor (IC 50 : 0.9 nM) by increasing the apparent affinity for H + of ASIC1a. Psalmotoxin 1 can induce cell apoptosis , also inhibits cell migration, proferliration and invasion of cancer cells. Psalmotoxin 1 can be used in the research of cancers, or neurological disease [1] [3] [4] [6]. Uses: Scientific research. Group: Peptides. Alternative Names: PcTx1; Psalmopoeus cambridgei toxin-1. CAS No. 880107-52-8. Pack Sizes: 100 μg. Product ID: HY-P1411. | |
| PSB-0739 | PSB-0739 is a high-affinity potent, competitive, nonselective platelet P2Y12 receptor antagonist with a Ki values of 24.9 nM. The P2Y12 receptor plays a crucial role in platelet aggregation. Antithrombotic effect[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1052087-90-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108660. | |
| PSB-1115 | PSB-1115 is a selective A2B Adenosine Receptor antagonist. PSB-1115 inhibits the 2,4,6-trinitrobenzenesulfonic acid (TNBS)-induced contraction inhibition of acetylcholine (ACh)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 152529-79-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103182. | |
| PSB-12379 | PSB-12379, a nucleotide analogue, is a potent Ecto-5'-Nucleotidase (CD73) inhibitor with Kis of 9.03 nM (rat) and 2.21 nM (human)[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1802226-78-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-100747. | |
| PSB-603 | PSB-603 is a potent and highly selective A 2B adenosine receptor antagonist exhibiting a K i value of 0.553 nM and virtually no affinity for the human and rat A 1 and A 2A and the human A 3 receptors up to a concentration of 10 μM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1092351-10-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103166. | |
| PSB-CB5 | PSB-CB5 is a potent and selective antagonist of GRP18. PSB-CB5 has the potential for the research of metabolic disease and obesity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1627710-30-8. Pack Sizes: 1 mg. Product ID: HY-44154. | |
| p-SCN-Bn-DOTA | p-SCN-Bn-DOTA is a bifunctional chelating agent. p-SCN-Bn-DOTA can simultaneously chelate radionuclides and link monoclonal antibody for radioimmunoresearch of tumor[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 127985-74-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114377. | |
| Pseudoginsenoside F11 | Pseudoginsenoside F11 (Ginsenoside A1), a component of Panax quinquefolium (American ginseng), has been demonstrated to antagonize the learning and memory deficits induced by scopolamine, morphine and methamphetamine in mice. Uses: Scientific research. Group: Natural products. Alternative Names: Ginsenoside A1. CAS No. 69884-00-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-N0541. | |
| Pseudoginsenoside RT5 | Pseudoginsenoside RT5 is isolated from Panax quinquefolium [1]. Uses: Scientific research. Group: Natural products. CAS No. 98474-78-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N0542. | |
| Pseudohypericin | Pseudohypericin and its congener Hypericin are the major hydroxylated phenanthroperylenediones present in Hypericum species. Pseudohypericin shows anti-HIV activity [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 55954-61-5. Pack Sizes: 1 mg. Product ID: HY-N0685. | |
| Pseudomonas quinolone signal | Pseudomonas Quinolone Signal (Compound C), a signaling molecule produced by Pseudomonas aeruginosa, can activate lasB. Pseudomonas Quinolone Signal can be used in the study of virulence regulation in Pseudomonas aeruginosa [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PQS. CAS No. 108985-27-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128200. | |
| Pseudomonic acid C | Pseudomonic acid C, an antibiotic, possesses antibacterial activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 71980-98-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-133056. | |
| Pseudopelletierine | Pseudopelletierine is an alkaloid compound that can be used as a enzyme substrate [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 552-70-5. Pack Sizes: 10 mM * 1 mL; 250 mg; 500 mg; 1 g. Product ID: HY-W017353. | |
| Pseudoprotodioscin | Pseudoprotodioscin, a furostanoside, inhibits SREBP1/2 and microRNA 33a/b levels and reduces the gene expression regarding the synthesis of cholesterol and triglycerides [1]. Uses: Scientific research. Group: Natural products. CAS No. 102115-79-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 20 mg; 50 mg. Product ID: HY-N0686. | |
| Pseudouridine | Pseudouridine is an isomer of uridine and the most abundant modified nucleoside in non-coding RNA. It fine-tunes and stabilizes regional structures in rRNA and tRNA, maintaining their functions in mRNA decoding, ribosome assembly, processing, and translation. Pseudouridine-modified tRNA fragments can inhibit aberrant protein synthesis and hold promise for research on myelodysplastic syndrome (MDS)-related leukemia. [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. CAS No. 1445-07-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113061. | |
| Pseudouridine 5'-triphosphate trisodium solution (100mM) | Pseudouridine 5'-triphosphate (Pseudo-UTP) trisodium solution (100 mM) is a modified ribonucleoside triphosphate. Pseudouridine 5'-triphosphate trisodium solution (100 mM) is substituted for UTP to improve the stability and translation efficiency of mRNA and reduce immunogenicity[1][2][3][4]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Pseudo-UTP trisodium solution (100mM). Pack Sizes: 5.5 mg (100 mM * 100 ?L in Water). Product ID: HY-141567A. | |
| PSI | PSI (Proteasome Inhibitor 1) is a potent proteasome inhibitor. PSI inhibits the proliferation of primary effusion lymphoma (PEL) cells. PSI has the potential for the research of Kaposis sarcoma-associated herpesvirus (KSHV) infection and KSHV-associated lymphomas [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Proteasome Inhibitor 1; Z-Ile-Glu(OtBu)-Ala-Leu-CHO. CAS No. 158442-41-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1258. | |
| PSMA-1007 | PSMA-1007 is a prostate-specific membrane antigen ( PSMA ) ligand. 18 F-labeled PSMA-1007 can be used as a PET tracer for prostate cancer imaging [1]. PSMA-1007 can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs). Uses: Scientific research. Group: Peptides. CAS No. 2226894-58-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-153550. | |
| PSMA-11 | PSMA-11 is a small molecule ligand that targets prostate-specific membrane antigen (PSMA) and has the ability to inhibit PSMA activity. PSMA-11 can be used to synthesize 68 Ga-PSMA-11, a positron emission tomography (PET) tracer that can be used to image advanced prostate cancer [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HBED-CC-PSMA. CAS No. 1366302-52-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125399. | |
| PSMA-BCH | PSMA-BCH (NOTA-PSMA) is a NOTA-conjugated precursor. NOTA is a bifunctional chelate which acts as the framework to construct PET imaging tools [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NOTA-PSMA. CAS No. 1703768-73-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-155483. | |
| PSMA I&T | PSMA I&T is an effective inhibitor of prostate-specific membrane antigen ( PSMA ). PSMA I&T can be used for SPECT/CT imaging and radionuclide studies in triple-negative breast cancer and prostate cancer (PCa) [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2192281-54-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-148761. | |
| PSMα3 | PSMα3 is a peptide for manipulating DCs to become tolerogenic for DC vaccination strategies. PSMα3 penetrates and modulates human monocyte-derived DCs by altering the TLR2- or TLR4-induced maturation, inhibiting pro- and anti-inflammatory cytokine production and reducing antigen uptake. PSMα3 is an important toxin released by the most virulent strains of methicillin-resistant Staphylococcus aureus (MRSA) [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 1001405-52-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P2358. | |
| PSN 375963 | PSN 375963 is a potent GPR119 agonist, with EC 50 s of 8.4 and 7.9 μM for human and mouse GPR119, respectively. PSN 375963 shows similar potency to the endogenous agonist oleoylethanolamide (OEA) [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 388575-52-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108258. | |
| PSNCBAM-1 | PSNCBAM-1 is a selective CB1 receptor allosteric antagonist with an EC 50 of 0.1 μM. PSNCBAM-1 can be used in the researches of obesity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 877202-74-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110179. | |
| Psoralen | Psoralen (Ficusin) is a coumarin isolated from the seeds of Fructus Psoraleae. Psoralen exhibits a wide range of biological properties, including anti-cancer, antioxidant, antidepressant, anticancer, antibacterial, and antiviral, et al [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Ficusin. CAS No. 66-97-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0053. | |
| Psoralidin | Psoralidin is a dual inhibitor of COX-2 and 5-LOX , regulates ionizing radiation (IR)-induced pulmonary inflammation.Anti-cancer, anti-bacterial, and anti-inflammatory properties [1]. Psoralidin significantly downregulates NOTCH1 signaling. Psoralidin also greatly induces ROS generation [2]. Uses: Scientific research. Group: Natural products. CAS No. 18642-23-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-N0232. | |
| Psoromic acid | Psoromic acid is a potent and selective RabGGTase (Rab geranylgeranyl transferase) inhibitor with an IC 50 value of 1.3 μM. Psoromic acid is an antioxidative agent. Psoromic acid exhibits a competitive type of HMGR inhibition and mixed type of ACE (angiotensin converting enzyme) inhibition [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Parellic acid. CAS No. 7299-11-8. Pack Sizes: 500 μg. Product ID: HY-130199. | |
| Psychosine | Psychosine (Galactosylsphingosine), a substrate of the galactocerebrosidase (GALC) enzyme, is a potential biomarker for Krabbe disease [1]. Psychosine is a highly cytotoxic lipid, capable of inducing cell death in a wide variety of cell types including, most relevantly to globoid cell leukodystrophy (GLD), oligodendrocytes. Psychosine causes cell death at least in part via apoptosis. Psychosine also is an inhibitor of PKC [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Galactosylsphingosine. CAS No. 2238-90-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-136490. | |
| PT1 | PT1 is an AMPKα1 activator that directly activates the inactive truncated forms of AMPKα1 monomers [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 331002-70-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103239. | |
| PT-179 | PT-179 is an orthogonal Thalidomide (HY-14658) derivative that targets cereblon without causing off-target degradation effects. PT-179 is able to specifically bind CRBN, form a ternary complex with a target protein fused to a zinc finger (ZF) degron, and mediate the degradation of the tagged protein. For example, PT-179 binds to the ubiquitin ligase substrate receptor cereblon by forming a complex with SD40 and efficiently degrades proteins N- or C-terminally fused to SD40 or SD36 (DC50 for eGFP: 4.5 nM and 14.3 nM). PT-179 can be used to develop compact protein degradation tagging platforms[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2924858-25-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-160695. | |
| PT-2385 | PT-2385 is a selective HIF-2? inhibitor with a Ki of less than 50 nM[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1672665-49-4. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12867. | |
| PT2399 | PT2399 is a potent and selective HIF-2α antagonist, which directly binds to HIF-2α PAS B domain with an IC 50 of 6 nM. PT2399 displays potent antitumor activity in vivo [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1672662-14-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-108697. | |
| PT-262 | PT-262 is a potent ROCK inhibitor with an IC 50 value of around 5 μM. PT-262 induces the loss of mitochondrial membrane potential and elevates the caspase-3 activation and apoptosis. PT-262 inhibits the ERK and CDC2 phosphorylation via a p53-independent pathway. PT-262 blocks cytoskeleton function and cell migration. PT-262 has anti-cancer activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 86811-36-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100035. | |
| PT-65 | PT-65 is a potent and selective GSK3 PROTAC degrader with the highest degradation capacity of GSK3α ( DC 50 = 28.3 nM) and GSK3β ( DC 50 = 34.2 nM) in SH-SY5Y cells. PT-65 can be used in Alzheimer's disease research [1].(Pink: GSK3 inhibitor (HY-15761); Black: linker; Blue: CRBN Ligand (HY-10984)). Uses: Scientific research. Group: Signaling pathways. CAS No. 2721998-87-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-153166. | |
| PT-91 | PT-91 is an agonist of GPR27. PT-91 exhibits high metabolic stability and brain exposure in mice [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3037561-48-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-163087. | |
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