MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Ulimorelin | Ulimorelin (TZP-101) is a ghrelin receptor (GRLN) agonist with an EC 50 of 29 nM and a K i of 16 nM. Ulimorelin is a prokinetic agent and causes vasorelaxation through competitive antagonist action at α1-adrenoceptors. Ulimorelin stimulates intestinal motility and is used for malnutrition [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TZP-101. CAS No. 842131-33-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-14903. |  |
| Ulinastatin | Ulinastatin (Uristatin) is a trypsin and serine protease inhibitor. Ulinastatin is the main protein binding inhibitor of various trypsin, chymotrypsin, and various pancreatic proteases. Ulinastatin shows neuroprotective, anti-inflammatory, anti-apoptotic, anti-oxidant effects [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Uristatin. CAS No. 80449-31-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134616. | |
| Ulipristal | Ulipristal (CDB 3236) is a selective progesterone receptor modulator (SPRM). Ulipristal binds to the progesteron receptor, thereby inhibiting PR-mediated gene expression, and interfering with progesterone activity in the reproductive system [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CDB-3236; Deacetyl CDB-2914. CAS No. 159811-51-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14959. | |
| Ulipristal acetate | Ulipristal acetate (CDB-2914) is an orally active, selective progesterone receptor modulator (SPRM). Ulipristal acetate stimulates the autophagic response selectively in leiomyoma cells. Ulipristal acetate has the potential for benign gynecological conditions treatment, such as uterine myoma [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CDB-2914. CAS No. 126784-99-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16508. | |
| Ulixacaltamide | Ulixacaltamide (Z944) is an orally available T-type calcium channel antagonist that can slow the progression of epilepsy. Ulixacaltamide effectively reduces tremor in a normal alkaline tremor animal model. Ulixacaltamide reverses thermal hyperalgesia and mediates pain relief [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Z944; PRAX-944. CAS No. 1199236-64-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120546. | |
| Ulixertinib | Ulixertinib (BVD-523; VRT752271) is a potent, orally active, highly selective, ATP-competitive and reversible covalent inhibitor of ERK1/2 kinases, with an IC 50 of <0.3 nM against ERK2. Ulixertinib (BVD-523; VRT752271) inhibits the phosphorylated ERK2 (pERK) and downstream kinase RSK (pRSK) in an A375 melanoma cell line [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BVD-523; VRT752271. CAS No. 869886-67-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-15816. | |
| Ulixertinib hydrochloride | Ulixertinib hydrochloride (BVD-523 hydrochloride) is a potent, orally active, highly selective, ATP-competitive and reversible covalent inhibitor of ERK1/2 kinases, with an IC 50 of <0.3 nM against ERK2. Ulixertinib hydrochloride inhibits the phosphorylated ERK2 (pERK) and downstream kinase RSK (pRSK) in an A375 melanoma cell line [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BVD-523 hydrochloride; VRT752271 hydrochloride. CAS No. 1956366-10-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15816A. | |
| ULK-101 | ULK-101 is a potent and selective ULK1 inhibitor, with IC 50 values of 1.6 nM and 30 nM for ULK1 and ULK2, respectively. ULK-101 suppresses autophagy and sensitizes cancer cells to nutrient stress [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2443816-45-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114490. | |
| Ulocuplumab | Ulocuplumab (Anti-Human CXCR4 Recombinant Antibody/BMS-936564/MDX1338) is a fully human IgG4 anti- CXCR4 antibody. Ulocuplumab induces apoptosis and inhibits CXCL12 mediated CXCR4 activation-migration of chronic lymphocytic leukemia (CLL). Ulocuplumab exhibits antitumor activity in established tumors including acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL), and multiple myeloma xenograft models [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BMS 936564; MDX 1338; Anti-Human CXCR4 Recombinant Antibody. CAS No. 1375830-34-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99272. | |
| Umbelliferone | Umbelliferone (7-Hydroxycoumarin), a natural orally active product of the coumarin family, is a fluorescing compound which can be used as a sunscreen agent. Umbelliferone induces cell cycle arrest, apoptosis and DNA fragmentation in HepG2 cells. Umbelliferone exhibits significant anticancer effects. Umbelliferone attenuates the alteration characteristics of allergic airway inflammation. Umbelliferone displays the neuroprotective effects and cross the blood-brain barrier. Umbelliferone exhibits anti-inflammatory and antioxidant effects in chronic alcohol-fed rats [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: 7-Hydroxycoumarin; Hydrangin; NSC 19790. CAS No. 93-35-6. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-N0573. | |
| Umbelliprenin | Umbelliprenin, a prenylated coumarin, is an antioxidant with anticancer, anti-inflammatory and immunomodulatory effects. Umbelliprenin inhibits lipoxygenase managing the inflammation pathways. In inflammatory macrophages, Umbelliprenin suppresses nitric oxide production as well as inducible nitric oxide synthase (NO synthase) [1]. Uses: Scientific research. Group: Natural products. CAS No. 23838-17-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-127029A. | |
| Umbralisib | Umbralisib (TGR-1202) is an orally active, potent and selective dual PI3Kδ and casein kinase-1-ε ( CK1ε ) inhibitor, with EC 50 of 22.2 nM and 6.0 μM, respectively. Umbralisib exhibits unique immunomodulatory effects on chronic lymphocytic leukemia (CLL) T cells. Umbralisib can be used for haematological malignancies reseach [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TGR-1202; RP5264. CAS No. 1532533-67-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12279. | |
| Umbralisib hydrochloride | Umbralisib (TGR-1202) hydrochloride is an orally active, potent and selective dual PI3Kδ and casein kinase-1-ε ( CK1ε ) inhibitor, with EC 50 of 22.2 nM and 6.0 μM, respectively. Umbralisib hydrochloride exhibits unique immunomodulatory effects on chronic lymphocytic leukemia (CLL) T cells. Umbralisib hydrochloride can be used for haematological malignancies reseach [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TGR-1202 hydrochloride; RP5264 hydrochloride. CAS No. 1532533-78-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12279C. | |
| Umeclidinium bromide | Umeclidinium bromide is a novel mAChR antagonist. The affinity ( K i ) of Umeclidinium bromide for the cloned human M1-M5 mAChRs ranges from 0.05 to 0.16 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GSK573719A. CAS No. 869113-09-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-12100. | |
| Umifenovir | Umifenovir is a potent, orally active broad-spectrum antiviral agent with activity against a number of enveloped and non-enveloped viruses. Umifenovir is used as an anti-influenza virus agent. Umifenovir could effectively inhibit the fusion of virus with host cells [1] [2]. Umifenovir is an efficient inhibitor of SARS-CoV-2 in vitro [2]. Umifenovir shows anti-inflammatory activity [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 131707-25-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14904. | |
| Umifenovir hydrochloride | Umifenovir hydrochloride is a potent, orally active broad-spectrum antiviral with activity against a number of enveloped and non-enveloped viruses. Umifenovir hydrochloride is used as an anti-influenza virus agent. Umifenovir hydrochloride could effectively inhibit the fusion of virus with host cells [1] [2]. Umifenovir hydrochloride is an efficient inhibitor of SARS-CoV-2 in vitro. Anti-inflammatory activity [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 131707-23-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-14904A. | |
| Umirolimus | Umirolimus, a macrocyclic triene lactone Rapamycin derivative, is powerful immunosuppressant and anti-inflammatory agent. Umirolimus has highly lipophilicity and can be used agent-eluting stent (DES) applications [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 851536-75-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122402. | |
| UNBS5162 | UNBS5162 is a pan-antagonist of CXCL chemokine expression, with anti-tumor activity. Uses: Scientific research. Group: Signaling pathways. CAS No. 956590-23-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16509. | |
| UNC0379 | UNC0379 is a selective, substrate-competitive inhibitor of lysine methyltransferase SETD8 ( KMT5A ) with an IC 50 of 7.3 μM, K D value of 18.3 μM. UNC0379 can be used in the research of inflammation and cancers, such as pulmonary fibrosis, ovarian cancer, neuroblastoma [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1620401-82-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12335. | |
| UNC0638 | UNC0638 selectively inhibits G9a and GLP histone methyltransferases with IC 50 of 15 nM and 19 nM, respectively. UNC0638 inhibits TNBC cell invasion and migration in vitro. UNC0638 is also an inhibitor of EHMT1/2 and induces fetal hemoglobin ( HbF ) expression in human erythroid progenitor cell culture. In addition, UNC0638 has anti- FMDV (foot-and-mouth disease virus) and anti- VSV (vesicular stomatitis virus) activities, with excellent potency and selectivity against multiple epigenetic and non-epigenetic targets [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1255580-76-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15273. | |
| UNC-2170 | UNC-2170 is a functionally active, fragment-like ligand for 53BP1 ( IC 50 =29 μM; K d =22 μM). UNC-2170 shows at least 17-fold selectivity for 53BP1 as compared to nine other methyl-lysine (Kme) reader proteins. 53BP1 is a Kme binding protein that plays a central role in DNA Damage Repair (DDR) pathways and is recruited to sites of double-strand breaks (DSB) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1648707-58-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115531. | |
| UNC6934 | UNC6934, a chemical probe targeting the PWWP domain, alters NSD2 nucleolar localization. Uses: Scientific research. Group: Signaling pathways. CAS No. 2561494-77-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145103. | |
| UNC8153 TFA | UNC8153 TFA is a potent and selective nuclear receptor-binding SET domain-containing 2 (NSD2) -targeted degrader with a K d of 24 nM. UNC8153 TFA reduces the cellular levels of both NSD2 protein and the H3K36me2 chromatin mark. UNC8153 TFA contains a simple warhead that confers proteasome-dependent degradation of NSD2 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2929304-61-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-157251. | |
| Undecane | Undecane has anti-allergic and anti-inflammatory activities on sensitized rat basophilic leukemia (RBL-2H3) mast cells and HaCaT keratinocytes. In sensitized mast cells, Undecane inhibits degranulation and the secretion of histamine and TNF-α [. Uses: Scientific research. Group: Natural products. CAS No. 1120-21-4. Pack Sizes: 10 mM * 1 mL; 10 g; 25 g. Product ID: HY-N8593. | |
| Undecanedioic acid | Undecanedioic acid is associated with intercellular matrix macromolecules and specifically with elastin. Uses: Scientific research. Group: Natural products. CAS No. 1852-04-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 1 g. Product ID: HY-W014125. | |
| Undecanoic acid | Undecanoic acid (Undecanoate) is a monocarboxylic acid with antimycotic property, which inhibits the production of exocellular keratinase, lipase and the biosynthesis of several phospholipids in T. rubrum [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Undecanoate; Hendecanoic acid. CAS No. 112-37-8. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-W004282. | |
| Undecylenate sodium | Undecylenate SodiumIt is an organic compound belonging to the class of carboxylates. It is formed by the reaction of undecylenic acid and sodium hydroxide. Undecylenate SodiumIt has a variety of applications in the cosmetic and personal care industries, especially as an antifungal agent in products such as face creams, lotions and shampoos. In addition, it can be used as a preservative in various formulations. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 3398-33-2. Pack Sizes: 5 g; 10 g; 25 g. Product ID: HY-W127452. | |
| Unesbulin | Unesbulin (PTC596) is an orally active and selective B-cell-specific Moloney murine leukemia virus integration site 1 ( BMI-1 ) inhibitor. Unesbulin downregulates MCL-1 and induces p53-independent mitochondrial apoptosis in acute myeloid leukemia (AML) cells. Unesbulin has anti-leukemic activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PTC596. CAS No. 1610964-64-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112041. | |
| Uniconazole | Uniconazole, a plant growth retardant, is a potent inhibitor of abscisic acid (ABA) catabolism with an IC 50 of 68 nM against ABA 8-hydroxylase. Uniconazole is a potent competitive inhibitor of CYP707A3 activity with a K i of 8 nM. Uniconazole evidently inhibits gibberellin biosynthesis, and brassinosteroid biosynthesis is also inhibited to some extent [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 83657-22-1. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-B0873. | |
| UniPR1331 | UniPR1331 is a 3β-hydroxy-Δ5-choline acid derivative that inhibits Eph-ephrin interactions. UniPR1331 interacts with VEGFR2 and blocks the interaction of VEGFR2 with its natural ligand vascular endothelial growth factor and subsequent autophosphorylation, signaling, and pro-angiogenic activation of endothelial cells in vitro. UniPR1331 also inhibits tumor cell-driven angiogenesis in zebrafish [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1809170-59-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-123927. | |
| Unoprostone | Unoprostone, a prostaglandin F2α analogs (PGAs), activates BK channels to reduce oxidative stress- and light-induced retinal cell death, and phagocytotic dysfunction. Unoprostone reduces intraocular pressure and is used topically for glaucoma or ocular hypertension [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 120373-36-6. Pack Sizes: 1 mg (26.14 mM * 100 μL in Methyl acetate). Product ID: HY-106916. | |
| Upacicalcet sodium | Upacicalcet sodium is an intravenous calcimimetic agent. Upacicalcet suppresses excessive parathyroid hormone (PTH) secretion, thereby lowering blood PTH levels, by acting directly on parathyroid cell membrane calcium-sensing receptors. Upacicalcet can be used for researching the disease of secondary hyperparathyroidism (SHPT) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2052969-18-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109106A. | |
| Upadacitinib | Upadacitinib (ABT-494) is a potent, orally active and selective Janus kinase 1 ( JAK1 ) inhibitor ( IC 50 =43 nM). Upadacitinib (ABT-494) displays approximately 74 fold selective for JAK1 over JAK2 (200 nM) in cellular assays dependent on specific, relevant cytokines. Upadacitinib (ABT-494) can be used for several autoimmune disorders research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABT-494. CAS No. 1310726-60-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-19569. | |
| Upamostat | Upamostat (WX-671) is a serine protease inhibitor. Upamostat is the orally available prodrug of the WX-UK1, which is a urokinase plasminogen activator (uPA) inhibitor. Uses: Scientific research. Group: Signaling pathways. Alternative Names: WX-671. CAS No. 590368-25-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16511. | |
| Upidosin | Upidosin (Rec 15/2739) is an α-1 adrenoceptor ( α-1 AR ) antagonist. Upidosin shows moderate selectivity for the α-1A AR subtype. Upidosin shows uroselectivity in urethra and prostate with a K b value of 2-3 nM higher than in ear artery and aorta with a K b value of 20-100 nM. Upidosin inhibits [3H]prazosin binding to cloned human α-1A adrenergic receptor. Upidosin can be used for the research of urethral obstruction [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Rec 15/2739; Recordati 15/2739; SB 216469. CAS No. 152735-23-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106954. | |
| Upifitamab | Upifitamab is an ADC Antibody (a naked antibody of upifitamab rilsodotin), which can be used for antibody-coupled agent (ADC) synthesis. Upifitamab rilsodotin is an ADC targeting NaPi2b and is used in ovarian cancer research, particularly in platinum-resistant recurrent ovarian cancer [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2254118-43-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99229. | |
| Uplarafenib | Uplarafenib (B-Raf IN 10) (Compound C09) is a BRAF inhibitor with an IC 50 between 50 and 100 nM. Uplarafenib shows antitumor activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: B-Raf IN 10. CAS No. 1425485-87-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148059. | |
| Uprifosbuvir | Uprifosbuvir is an antiviral agent. Uprifosbuvir is a NS5b inhibitor developed for the research of chronic hepatitis C virus [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IDX21437; MK-3682. CAS No. 1496551-77-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103487. | |
| Uprosertib | Uprosertib (GSK2141795) is a potent and selective pan-Akt inhibitor with IC 50 values of 180/328/38 nM for Akt1/Akt2/Akt3, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GSK2141795. CAS No. 1047634-65-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15965. | |
| Uracil | Uracil is a pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA. Uracil is a frequently occurring DNA base damage that results from the spontaneous or chemically induced deamination of cytosine and is mutagenic at the level of replication. Uracil could potentially alter transcriptional fidelity, resulting in production of mutant proteins [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. CAS No. 66-22-8. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g; 10 g. Product ID: HY-I0960. | |
| Urapidil | Urapidil is an α1 adrenoreceptor antagonist and a 5-HT 1A receptor agonist. Uses: Scientific research. Group: Signaling pathways. CAS No. 34661-75-1. Pack Sizes: 10 mM * 1 mL; 50 mg. Product ID: HY-B0716. | |
| Urapidil hydrochloride | Urapidil hydrochloride is an orally active α1-adrenoceptor antagonist and 5-HT 1A receptor agonist with a p IC 50 of 6.13 and 4.38 against α1- and α2-adrenoceptor, respectively. Urapidil hydrochloride shows antihypertensive effect [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 64887-14-5. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B0354A. | |
| Urapidil (hydrochloride) (Standard) | Urapidil (hydrochloride) (Standard) is the analytical standard of Urapidil (hydrochloride). This product is intended for research and analytical applications. Urapidil hydrochloride is an orally active α1-adrenoceptor antagonist and 5-HT 1A receptor agonist with a p IC 50 of 6.13 and 4.38 against α1- and α2-adrenoceptor, respectively. Urapidil hydrochloride shows antihypertensive effect [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 64887-14-5. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0354AR. | |
| URAT1 inhibitor 8 | URAT1 inhibitor 8 (example 247) is a potent URAT1 inhibitor, with an IC 50 of 0.001 μM. URAT1 inhibitor 8 can be used for gout research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1632005-33-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153971. | |
| URAT1&XO inhibitor 1 | URAT1&XO inhibitor 1 (compound 29) is a dual inhibitor of both URAT1 ( IC 50 =~10 μM) and Xanthine Oxidase ( IC 50 =1.01 μM). URAT1&XO inhibitor 1 results hypouricemic effect in potassium oxonate-induced hyperuricemia rat model. URAT1&XO inhibitor 1 is used for hyperuricemia research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2669726-78-5. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-153968. | |
| URAT1&XO inhibitor 2 | URAT1&XO inhibitor 2 (Compound BDEO) is a dual inhibitor of xanthine oxidase and URAT1 , with IC 50 of 3.3 μM for xanthine oxidase. URAT1&XO inhibitor 2 blocks uptake of uric acid in HEK293 cells expressing URAT1, with a K i value of 0.145 μM. URAT1&XO inhibitor 2 decreases serum urate level and uric acid excretion in hyperuricemic mice. URAT1&XO inhibitor 2 can be used for research of hyperuricemia [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1239488-96-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153972. | |
| Urate oxidase, Microorganism | Urate oxidase, Microorganism (Uox), i.e., uricase, is often used in biochemical studies. Urate oxidase is a peroxisomal enzyme that catalyzes the oxidation of uric acid to allantoin in most mammals [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Uox. CAS No. 9002-12-4. Pack Sizes: 1 KU; 5 KU. Product ID: HY-P2921. | |
| URB-597 | URB-597 (KDS-4103) is an orally bioavailable and selective FAAH inhibitor. URB-597 inhibits FAAH activity with an IC 50 s of approximately 5 nM in rat brain membranes, 0.5 nM in intact rat neurons, 3 nM in human liver microsomes. Antidepressant-like effects. Analgesic activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KDS-4103. CAS No. 546141-08-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10864. | |
| Urea | Urea is a powerful protein denaturant via both direct and indirect mechanisms [1]. A potent emollient and keratolytic agent [2]. Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function [3]. Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry. Uses: Scientific research. Group: Natural products. Alternative Names: Carbonyl diamide. CAS No. 57-13-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 5 g. Product ID: HY-Y0271. | |
| Urea-13C | Urea- 13 C is the 13 C labelled urea. The Urea- 13 C breath test ( 13 C-UBT) is one of the best methods for the diagnosis of Helicobacter pylori infection[1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 58069-82-2. Pack Sizes: 1 mg; 50 mg; 100 mg. Product ID: HY-118877. | |
| Urea-13C,15N2 | Urea- 13 C, 15 N 2 is the 13 C and 15 N labeled Urea[1]. Urea is a powerful protein denaturant via both direct and indirect mechanisms[1]. A potent emollient and keratolytic agent[2]. Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function[3]. Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 58069-83-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-Y0271S2. | |
| Urease, Jack bean | Urease, Jack bean is derived from jack bean and Catalyzes hydrolysis of urea to carbon dioxide and ammonia. Urease, Jack bean is useful in the determination of urea in body fluids. Uses: Scientific research. Group: Signaling pathways. CAS No. 9002-13-5. Pack Sizes: 10 KU; 20 KU. Product ID: HY-P2767. | |
| Ureidopropionic acid | Ureidopropionic acid (3-Ureidopropionic acid) is an intermediate in the metabolism of uracil. Uses: Scientific research. Group: Natural products. Alternative Names: 3-Ureidopropionic acid. CAS No. 462-88-4. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-113285. | |
| Urethane | Urethane (Ethyl carbamate), the ethyl ester of carbamic acid, is a byproduct of fermentation found in various food products. Urethane has the ability to suppress bacterial , protozoal , sea urchin egg, and plant tissue growth in vitro [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Ethyl carbamate; Carbamic acid ethyl ester; Ethylurethane. CAS No. 51-79-6. Pack Sizes: 10 mM * 1 mL; 5 g; 10 g. Product ID: HY-B1207. | |
| Uric acid | Uric acid, scavenger of oxygen radical , is a very important antioxidant that help maintains the stability of blood pressure and antioxidant stress. Uric acid can remove reactive oxygen species (ROS) such as singlet oxygen and peroxynitrite, inhibiting lipid peroxidation [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 69-93-2. Pack Sizes: 500 mg; 1 g. Product ID: HY-B2130. | |
| Uric acid sodium | Uric acid sodium (Monosodium urate), scavenger of oxygen radical , is a very important antioxidant that help maintains the stability of blood pressure and antioxidant stress. Uric acid sodium can remove reactive oxygen species (ROS) such as singlet oxygen and peroxynitrite, inhibiting lipid peroxidation [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Monosodium urate. CAS No. 1198-77-2. Pack Sizes: 200 mg. Product ID: HY-B2130A. | |
| Uric acid (Standard) | Uric acid (Standard) is the analytical standard of Uric acid. This product is intended for research and analytical applications. Uric acid, scavenger of oxygen radical, is a very important antioxidant that help maintains the stability of blood pressure and antioxidant stress. Uric acid can remove reactive oxygen species (ROS) such as singlet oxygen and peroxynitrite, inhibiting lipid peroxidation [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 69-93-2. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B2130R. | |
| Uricase (Recombinant) | Uricase, Arthrobacter globiformis is a peroxidase enzyme responsible for catalyzing the oxidative reaction of uric acid, converting it into the soluble product allantoin. Uricase, Arthrobacter globiformis can be used for the determination of uric acid levels in serum. The lack of uricase in mammals can lead to kidney diseases caused by the accumulation of uric acid. Uricase, Arthrobacter globiformis can be utilized in research on gout and hyperuricemia [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Uox (Recombinant). CAS No. 9002-12-4. Pack Sizes: 1 KU. Product ID: HY-P2921C. | |
| Uridine | Uridine (β-Uridine) is a nucleoside compound composed of uracil and a ribose ring, which are connected by a β-N1-glycosidic bond [1]. Uses: Scientific research. Group: Natural products. Alternative Names: β-Uridine. CAS No. 58-96-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B1449. | |
| Uridine-5'-diphosphate disodium salt | Uridine-5'-diphosphate disodium salt is a potent, selective P2Y 6 receptor native agonist ( EC 50 =300 nM; pEC 50 =6.52 for human P2Y 6 receptor). Uridine-5'-diphosphate disodium salt, an endogenous metabolite , catalyzes the glucuronidation of a wide array of substrates and is used in nucleic acid (RNA) biosynthesis [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 27821-45-0. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-W010832. | |
| Uridine 5'-monophosphate | Uridine 5'-monophosphate (5'-Uridylic acid) is an orally active mitochondrial ATP-dependent potassium channel activator that has a protective effect on the heart. Uridine 5'-monophosphate can promote the synthesis of CDP-choline and induce apoptosis in intestinal epithelial cells, which is beneficial for gut development and reduces diarrhea [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: 5'-Uridylic acid. CAS No. 58-97-9. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-101981. | |
| Uridine 5'-monophosphate disodium salt | Uridine 5'-monophosphate disodium salt is component used for RNA synthesis. Uses: Scientific research. Group: Natural products. CAS No. 3387-36-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 1 g; 5 g. Product ID: HY-W013175. | |
| Uridine 5'-monophosphate (Standard) | Uridine 5'-monophosphate (Standard) is the analytical standard of Uridine 5'-monophosphate. This product is intended for research and analytical applications. Uridine 5'-monophosphate (5'-Uridylic acid) is an orally active mitochondrial ATP-dependent potassium channel activator that has a protective effect on the heart. Uridine 5'-monophosphate can promote the synthesis of CDP-choline and induce apoptosis in intestinal epithelial cells, which is beneficial for gut development and reduces diarrhea. Uses: Scientific research. Group: Natural products. Alternative Names: 5'-Uridylic acid (Standard). CAS No. 58-97-9. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101981R. | |
| Uridine (Standard) | Uridine (Standard) is the analytical standard of Uridine. This product is intended for research and analytical applications. Uses: Scientific research. Group: Natural products. CAS No. 58-96-8. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1449R. | |
| Uridine triacetate | Uridine triacetate (Tri-O-acetyl uridine) is an orally active proagent of Uridine (HY-B1449). Uridine triacetate is quickly absorbed in the gut, and is rapidly deacetylated in the circulation to yield free uridine. Uridine triacetate is used for the research of 5-fluorouracil (5-FU) and capecitabine toxicity, or early-onset cardiac or central nervous system (CNS) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Tri-O-acetyl uridine. CAS No. 4105-38-8. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-14905. | |
| Urocanic acid | Urocanic acid, produced in the upper layers of mammalian skin, is a major absorber of ultraviolet radiation (UVR). Uses: Scientific research. Group: Natural products. CAS No. 104-98-3. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-113008. | |
| Urocortin, human | Urocortin, human, a 40-aa neuropeptide, acts as a selective agonist of endogenous CRF 2 receptor , with K i s of 0.4, 0.3, and 0.5 nM for hCRF 1 , rCRF 2α and mCRF 2β , respectively. Uses: Scientific research. Group: Peptides. Alternative Names: Urocortin (human); Human urocortin; Human urocortin 1; Human urocortin I. CAS No. 176591-49-4. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-P1295. | |
| Urokinase, Human urine | Urokinase (peptidolytic) (EC 3.4.21.73) is a serine protease, an inactive form (zymogen) of the serine protease plasminogen. Activation of plasmin triggers a proteolytic cascade reaction, which in turn participates in thrombolysis or extracellular matrix degradation, implicated in vascular disease and cancer-related research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Urokinase-type plasminogen activator; Uronase; Win 22005; Win-Kinase. CAS No. 9039-53-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-108904. | |
| Urolithin A | Urolithin A, a gut-microbial metabolite of ellagic acid, exerts anti-inflammatory, antiproliferative, and antioxidant properties. Urolithin A induces autophagy and apoptosis , suppresses cell cycle progression, and inhibits DNA synthesis [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 1143-70-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100599. | |
| Urolithin B | Urolithin B is one of Ellagitannins' slow microbial products, and has anti-inflammatory and anti-inflammatory effects. Urolithin B suppresses NF-κB activity. Urolithin B suppresses JNK , ERK and Akt 's oxidation, and increases AMPK 's oxidation. Urolithin B is also a quantitative change factor for bone and skin quality [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 1139-83-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-126307. | |
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