MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Venlafaxine hydrochloride (Standard) | Venlafaxine (hydrochloride) (Standard) is the analytical standard of Venlafaxine (hydrochloride). This product is intended for research and analytical applications. Venlafaxine hydrochloride (Wy 45030 hydrochloride) is an orally active, potent serotonin (5-HT)/norepinephrine (NE) reuptake dual inhibitor. Venlafaxine is an antidepressant [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Wy 45030 hydrochloride (Standard). CAS No. 99300-78-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0196AR. |  |
| Vepdegestrant | Vepdegestrant (ARV-471) is an orally active PROTAC estrogen receptor degrader against breast cancer. Vepdegestrant is a hetero-bifunctional molecule that facilitates the interactions between estrogen receptor alpha and an intracellular E3 ligase complex. Vepdegestrant leads to the ubiquitylation and subsequent degradation of estrogen receptors via the proteasome. Vepdegestrant robustly degrades ER in ER-positive breast cancer cell lines with a half-maximal degradation concentration ( DC 50 ) of about 2 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ARV-471. CAS No. 2229711-68-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138642. | |
| Veralipride | Veralipride is a D2 receptor antagonist. It is an alternative antidopaminergic treatment for menopausal symptoms. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (±)-Veralipride; LIR166. CAS No. 66644-81-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101797. | |
| Verapamil | Verapamil ((±)-Verapamil) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor. Verapamil also inhibits CYP3A4. Verapamil has the potential for high blood pressure, heart arrhythmias and angina research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (±)-Verapamil; CP-16533-1. CAS No. 52-53-9. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-14275. | |
| Verapamil hydrochloride | Verapamil hydrochloride ((±)-Verapamil hydrochloride) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor. Verapamil hydrochloride also inhibits CYP3A4. Verapamil hydrochloride has the potential for high blood pressure, heart arrhythmias and angina research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (±)-Verapamil hydrochloride; CP-16533-1 hydrochloride. CAS No. 152-11-4. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-A0064. | |
| Veratraldehyde | Veratraldehyde is an important chemical used in perfumery, agrochemical, and pharmaceutical industries. Uses: Scientific research. Group: Natural products. CAS No. 120-14-9. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-N1096. | |
| Veratramine | Veratramine(NSC17821; NSC23880) is useful as a signal transduction inhibitor for treating tumors. Uses: Scientific research. Group: Natural products. Alternative Names: NSC17821; NSC23880. CAS No. 60-70-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0837. | |
| Veratric acid | Veratric acid (3,4-Dimethoxybenzoic acid) is an orally active phenolic compound derived from vegetables and fruits, has antioxidant [1] and anti-inflammatory activities [3]. Veratric acid also acts as a protective agent against hypertension-associated cardiovascular remodelling [2]. Veratric acid reduces upregulated COX-2 expression, and levels of PGE2, IL-6 after UVB irradiation [3]. Uses: Scientific research. Group: Natural products. Alternative Names: 3,4-Dimethoxybenzoic acid. CAS No. 93-07-2. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-N2007. | |
| Veratric acid (Standard) | Veratric acid (Standard) is the analytical standard of Veratric acid. This product is intended for research and analytical applications. Veratric acid (3,4-Dimethoxybenzoic acid) is an orally active phenolic compound derived from vegetables and fruits, has antioxidant [1] and anti-inflammatory activities [3]. Veratric acid also acts as a protective agent against hypertension-associated cardiovascular remodelling [2]. Veratric acid reduces upregulated COX-2 expression, and levels of PGE2, IL-6 after UVB irradiation [3]. Uses: Scientific research. Group: Natural products. CAS No. 93-07-2. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N2007R. | |
| Veratridine | Veratridine (3-Veratroylveracevine) is a plant neurotoxin, a voltage-gated sodium channels ( VGSCs ) agonist. Veratridine inhibits the peak current of Nav1.7, with an IC 50 of 18.39?μM. Veratridine regulates sodium ion channels mainly by activating sodium ion channels, preventing channel inactivation and increasing sodium ion flow [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: 3-Veratroylveracevine. CAS No. 71-62-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N6691. | |
| Veratrole | Veratrole is a key compound found widely in plants that attracts pollinators. Veratrole can be used as a safe fragrance ingredient with low acute and administration toxicity [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 91-16-7. Pack Sizes: 10 mM * 1 mL; 100 g. Product ID: HY-B1812. | |
| Verbascoside | Verbascoside is isolated from Acanthus mollis , acts as an ATP-competitive inhibitor of PKC , with an IC 50 of 25 μM, and has antitumor, anti-inflammatory and antineuropathic pain activity. Uses: Scientific research. Group: Natural products. Alternative Names: Acteoside; Kusaginin; TJC160. CAS No. 61276-17-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0021. | |
| Verbenalin | Verbenalin is Verbena glycoside, with anti-inflammatory, anti-fungal anti-virus activities. Verbenalin can be used for the research of prostatitis. Verbenalin can reduce cerebral ischemia-reperfusion injury [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 548-37-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N2014. | |
| Verbenone | Verbenone ((-)-Verbenone) is a natural terpene in leaves of the tree, Verbena officinalis [1]. Verbenone has anti-aggregation pheromone and interrupts the attraction of bark beetles to their aggregation pheromones [2]. Uses: Scientific research. Group: Natural products. Alternative Names: (-)-Verbenone. CAS No. 1196-01-6. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-N6661. | |
| Verdinexor | Verdinexor(KPT-335) is a novel, orally bioavailable selective inhibitor of nuclear export (SINE), inhibits nuclear export protein Exportin 1(XPO1/CRM1) against canine tumor cell lines; also reduce influenza virus replication in vitro and in vivo. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KPT-335. CAS No. 1392136-43-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15970. | |
| Verdiperstat | Verdiperstat (AZD3241) is a selective, irreversible and orally active myeloperoxidase (MPO) inhibitor, with an IC 50 of 630 nM, and can be used in the research of neurodegenerative brain disorders. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AZD3241. CAS No. 890655-80-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17646. | |
| Verekitug | Verekitug is an anti- CRLF2 human IgG1 κ monoclonal antibody [1]. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001). Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2768386-15-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990774. | |
| Vericiguat | Vericiguat (BAY1021189) is a potent, orally available and soluble guanylate cyclase stimulator. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY1021189. CAS No. 1350653-20-1. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16774. | |
| Verinurad | Verinurad (RDEA3170) is a highly potent and specific URAT1 inhibitor with an IC 50 of 25 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RDEA3170. CAS No. 1352792-74-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16733. | |
| Vernakalant Hydrochloride | Vernakalant hydrochloride is a mixed voltage- and frequency-dependent Na + and atria-preferred K + channel blocker. IC 50 for block by Vernakalant of wild-type and mutant Kv1.5 channels Fractional block is 13.35±0.93 μM, 0.61±0.03 μM, and 1.63±0.09 μM for Kv1.5 channel wt , Kv1.5 channel I508F , Kv1.5 channel T479A , respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RSD1235 hydrochloride. CAS No. 748810-28-8. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14183. | |
| Verrucarin A | Verrucarin A (Muconomycin A), a Type D macrocyclic mycotoxin derived from the pathogen fungus Myrothecium verrucaria , is an inhibitor of protein synthesis. Verrucarin A inhibits growth of leukemia cell lines and activates caspases and apoptosis and inflammatory signaling in macrophages. Verrucarin A effectively increased the phosphorylation of p38 MAPK and diminished the phosphorylation of ERK/Akt. Verrucarin A caused cell cycle deregulation through the induction of p21 and p53 [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Muconomycin A. CAS No. 3148-9-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-107426. | |
| Verteporfin | Verteporfin (CL 318952) is a photosensitizer for photodynamic therapy to eliminate the abnormal blood vessels in the eye associated with conditions such as age-related macular degeneration. Verteporfin is a YAP inhibitor which disrupts YAP-TEAD interactions. Verteporfin induces cell apoptosis [1]. Verteporfinis an autophagy inhibitor that blocks autophagy at an early stage by inhibiting autophagosome formation [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CL 318952. CAS No. 129497-78-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0146. | |
| Verubecestat | Verubecestat (MK-8931) is an orally active, high-affinity BACE1 and BACE2 inhibitor with K i values of 2.2 nM and 0.38 nM. Verubecestat effectively reduces Aβ40 and has the potential for Alzheimer's Disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-8931. CAS No. 1286770-55-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16759. | |
| (-)-Vesamicol | (-)-Vesamicol (AH5183) is an inhibitor of acetylcholine transport into synaptic vesicles, with the IC 50 of 75 nM [1]. (-)-Vesamicol can be used for release and recycling of synaptic vesicles study [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AH5183. CAS No. 112709-59-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113995. | |
| Vesatolimod | Vesatolimod (GS-9620) is a potent, selective and orally active agonist of Toll-Like Receptor (TLR7) with an EC 50 of 291 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GS-9620. CAS No. 1228585-88-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15601. | |
| Vesnarinone | Vesnarinone (OPC-8212) is an orally active phosphodiesterase 3 ( PDE3 ) inhibitor. Vesnarinone can increase in calcium flux and decrease in potassium flux. Vesnarinone shows dose-dependent positive inotropic activity. Vesnarinone can be used in heart failure research [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: OPC-8212. CAS No. 81840-15-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15297. | |
| Vestitol | Vestitol is the compound isolated from leaves of Trifolium arvense [1]. Uses: Scientific research. Group: Natural products. Alternative Names: (±)-Vestitol. CAS No. 56701-24-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N8744. | |
| VGX-1027 | VGX-1027 is an orally active isoxazole compound that exhibits various immunomodulatory properties. VGX-1027 targets macrophages, reducing the production of the proinflammatory mediators TNF-α, IL-1β, IL-10. VGX-1027 has antidiabetogenic effects by limiting cytokine-mediated immunoinflammatory events [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GIT 27. CAS No. 6501-72-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15507. | |
| Vialinin A | Vialinin A (Terrestrin A) is a p-terphenyl compound with antioxidant properties [1]. Vialinin A is a potent inhibitor of TNF-α, USP4, USP5, and sentrin/SUMO-specific protease 1 (SENP1). Vialinin A (Terrestrin A) can be used for autoimmune diseases and cancer research [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Terrestrin A. CAS No. 858134-23-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-103435. | |
| Vibecotamab | Vibecotamab (XmAb14045) is a potent bispecific antibody against CD123 and CD3 that stimulates T cell-mediated targeted killing of CD123-expressing cells. Vibecotamab has antitumor activity and can be used in acute myeloid leukaemia studies [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: XmAb14045. CAS No. 2138442-13-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99521. | |
| Vibegron | Vibegron (MK-4618) is a potent, highly selective and orally active β 3 -adrenoceptor agonist ( EC 50 =1.1 nM). Vibegron can be used for severe urgency urinary incontinence related to overactive bladder [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-4618. CAS No. 1190389-15-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19933. | |
| Vibostolimab | Vibostolimab is an anti-TIGIT ( T cell immunoglobulin and ITIM domain ) monoclonal antibody. Vibostolimab shows antitumor activity, and can be used in non-small cell lung cancer (NSCLC) and melanoma research [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2231305-30-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99202. | |
| Vicagrel | Vicagrel is a potent, safe and orally active antiplatelet agent, which works by irreversibly inhibiting P2Y12 receptor. Vicagrel can be used for the research of blood clots in coronary artery disease, peripheral vascular disease, and cerebrovascular disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1314081-53-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-118284. | |
| Vicenin 2 | Vicenin 2, a flavonoid, is an orally active angiotensin-converting enzyme (ACE) inhibitor ( IC 50 of 43.83 μM) [1]. Vicenin 2 has radioprotective, anti-nociceptive effects, anti-glycation anti-inflammatory, antioxidant, anticancer, antiangiogenic properties [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 23666-13-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N2165. | |
| Vicine | Vicine, an alkaloid glycoside found mainly in fava beans, is toxic in individuals who have a hereditary loss of the enzyme glucose-6-phosphate dehydrogenase and may cause haemolytic anaemia.Vicine is an inactive compound that is hydrolysed by the intestinal microflora to a highly reactive free radical generating compound, the aglycone divicine when Vicine enters the body through food [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 152-93-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N2093. | |
| Vicriviroc maleate | Vicriviroc maleate (SCH-417690 maleate; SCH-D maleate) is a potent, selective, oral bioavailable and CNS penetrated antagonist of CCR5 , with a K i of 2.5 nM, and also inhibits HIV-1 in PBMC cells, with IC 90 s of 3.3 nM (JrFL), 2.8 nM (ADA-M), 1.8 nM (301657), 4.9 nM (JV1083) and 10 nM (RU 570). Uses: Scientific research. Group: Signaling pathways. Alternative Names: SCH-417690 maleate; SCH-D maleate. CAS No. 599179-03-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17377. | |
| Vidarabine | Vidarabine (Ara-A) an antiviral agent which is active against herpes simplex and varicella zoster viruses [1] [2]. Vidarabine has IC 50 s of 9.3 μg/ml for HSV-1 and 11.3 μg/ml for HSV-2 [2]. Vidarabine also has anti- orthopoxvirus activity [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Ara-A; Adenine Arabinoside; 9-β-D-Arabinofuranosyladenine. CAS No. 5536-17-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-B0277. | |
| Vidarabine monohydrate | Vidarabine monohydrate is an adenine arabinoside. Vidarabine monohydrate an antiviral agent which is active against herpes simplex viruses ( HSV ) and varicella zoster viruses [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 24356-66-9. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-N6666. | |
| Vidarabine phosphate | Vidarabine phosphate (Ara-AMP), an antiviral agent, inhibits chronic HBV infection [1] [2]. Vidarabine phosphate also against herpes simplex and varicella zoster viruses [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ara-AMP; ara-A 5'-monophosphate. CAS No. 29984-33-6. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0277A. | |
| Vidofludimus | Vidofludimus is an orally active inhibitor for dihydroorotate dehydrogenase (DHODH) and also is a novel modulator for farnesoid X receptor (FXR). Vidofludimus, as an immunomodulatory agent, can be used for the research of autoimmune disorders such as inflammatory bowel disease (IBD). Vidofludimus also can be used for the research of fatty liver by targeting FXR [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 4sc-101; SC12267. CAS No. 717824-30-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14908. | |
| Vigabatrin | Vigabatrin (γ-Vinyl-GABA), an inhibitory neurotransmitter GABA vinyl-derivative, is an orally active and irreversible GABA transaminase inhibitor. Vigabatrin is an antiepileptic agent, which acts by increasing GABA levels in the brain by inhibiting the catabolism of GABA by GABA transaminase [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: γ-Vinyl-GABA. CAS No. 68506-86-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15399. | |
| Vigabatrin hydrochloride | Vigabatrin hydrochloride (γ-Vinyl-GABA hydrochloride), a inhibitory neurotransmitter GABA vinyl-derivative, is an orally active and irreversible GABA transaminase inhibitor. Vigabatrin hydrochloride is an antiepileptic agent, which acts by increasing GABA levels in the brain by inhibiting the catabolism of GABA by GABA transaminase [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: γ-Vinyl-GABA hydrochloride. CAS No. 1391054-02-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-B0033. | |
| Vilanterol | Vilanterol (GW642444) is a long-acting β 2 -adrenoceptor (β 2 -AR) agonist with 24 h activity. The pEC 50 s for β 2 -AR,β 1 -AR and β 3 -AR is 10.37±0.05, 6.98±0.03 and 7.36±0.03, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GW642444. CAS No. 503068-34-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14300. | |
| Vilanterol trifenatate | Vilanterol trifenatate (GW642444 trifenatate) is a long-acting β 2 -adrenoceptor (β 2 -AR) agonist with inherent 24-hour activity. The pEC 50 s for β 2 -AR, β 1 -AR and β 3 -AR are 10.37, 6.98 and 7.36, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GW642444 trifenatate. CAS No. 503070-58-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14300A. | |
| Vilaprisan | Vilaprisan is a selective progesterone receptor modulator (SPRM), which targets progesterone receptors. Vilaprisan can inhibit cell proliferation and stimulate apoptosis. Vilaprisan has oral efficacy and anti-proliferative activity against uterine leiomyoma (UF [1] ). Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 1002670. CAS No. 1262108-14-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-16775. | |
| Vilastobart | Vilastobart is an anti- CTLA4 human IgG1 κ monoclonal antibody [1]. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001). Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2760549-50-4. Pack Sizes: 1 mg. Product ID: HY-P990775. | |
| Vilazodone | Vilazodone (EMD 68843; SB 659746A) is a potent, selective and orally active serotonin reuptake inhibitor (SSRI) and partial 5-HT 1 A receptor agonist. Vilazodone exhibits antidepressant efficacy in vivo can be used for the research of major depressive disorder (MDD) and affective disorders [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EMD 68843; SB659746A. CAS No. 163521-12-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-14262. | |
| Vilazodone Hydrochloride | Vilazodone Hydrochloride (EMD 68843 Hydrochloride) is a serotonin transporter (SER) inhibitor and 5-HT 1A receptor partial agonist. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EMD 68843 Hydrochloride; SB659746A Hydrochloride. CAS No. 163521-08-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-14261. | |
| Vildagliptin | Vildagliptin (LAF237) is a potent, stable, selective dipeptidyl peptidase IV ( DPP-IV ) inhibitor with an IC 50 of 3.5 nM in human Caco-2 cells. Vildagliptin possesses excellent oral bioavailability and potent antihyperglycemic activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LAF237; NVP-LAF 237. CAS No. 274901-16-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-14291. | |
| Villocarine A | Villocarine A is a natural vasorelaxant indole alkaloid [1]. Uses: Scientific research. Group: Natural products. CAS No. 1319743-81-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N11478. | |
| Vilobelimab | Vilobelimab (CaCP-29, IFX-1) is a monoclonal anti- C5a antibody to the allergen C5a, a pro-inflammatory complement division product that plays a central role in mediating organ dysfunction. Vilobelimab acts as a C5a inhibitor, inhibiting neutrophil activation, chemotaxis, and reducing inflammatory signalling, and may be used in studies related to sepsis, COVID-19, etc [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: CaCP-29, IFX-1. CAS No. 2250440-41-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99520. | |
| Viloxazine | Viloxazine (Viloxazin) is a norepinephrine reuptake inhibitor, also a potent 5-HT 2C agonist and 5-HT 2B antagonist with an EC 50 of 32 μM and an IC 50 of 27 μM for 5-HT 2C and 5-HT 2B , respectively. The mechanism of action of Viloxazine predominantly involves serotonergic and noradrenergic pathways. Viloxazine can be used for researching depression [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Viloxazin; Emovit. CAS No. 46817-91-8. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W380450. | |
| Viloxazine hydrochloride | Viloxazine hydrochloride is a non-brain-penetrant, selective norepinephrine transporter (NET) inhibitor ( IC 50 =0.26 μM) and 5-HT receptor modulator. Viloxazine antagonizes 5-HT2B receptors ( K i =4.2 μM) and agonizes 5-HT2C receptors ( EC 50 =32 μM), respectively, and enhances 5-HT neurotransmission by modulating 5-HT2B/C receptors. Viloxazine also competitively inhibits NET from increasing NE and DA levels in the synaptic cleft, and can be used in the study of attention deficit hyperactivity disorder (ADHD) [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Viloxazin hydrochloride; Emovit hydrochloride. CAS No. 35604-67-2. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125784. | |
| Vimseltinib | Vimseltinib (DCC-3014) is a c-FMS ( CSF-IR ) and c-Kit dual inhibitor extracted from patent WO2014145025A2, Compound Example 10, has IC 50 s of <0.01 μM and 0.1-1 μM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DCC-3014. CAS No. 1628606-05-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136256. | |
| Vinblastine sulfate | Vinblastine sulfate is a cytotoxic alkaloid used against various cancer types. Vinblastine sulfate inhibits the formation of microtubule and suppresses nAChR with an IC 50 of 8.9 μM. Uses: Scientific research. Group: Natural products. Alternative Names: Vincaleukoblastine sulfate salt. CAS No. 143-67-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13780. | |
| Vinburnine | Vincamone is a vinca alkaloid and a metabolite of vincamine, is a vasodilator. Uses: Scientific research. Group: Natural products. Alternative Names: (-)-Eburnamonine; (-)-Vincamone. CAS No. 4880-88-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg. Product ID: HY-B1180. | |
| Vincamine | Vincamine is a monoterpenoid indole alkaloid extracted from the Madagascar periwinkle. Vincamine is a peripheral vasodilator and exerts a selective vasoregulator action on the brain microcapilar circulation [1]. Vincamine is a GPR40 agonist and acts as a β-cell protector by ameliorating β-cell dysfunction and promoting glucose-stimulated insulin secretion (GSIS). Vincamine improves glucose homeostasis in vivo , and has the potential for the type 2 diabetes mellitus (T2DM) research [2]. Uses: Scientific research. Group: Natural products. CAS No. 1617-90-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B1021. | |
| Vincristine sulfate | Vincristine sulfate is an antitumor vinca alkaloid which inhibits microtubule formation in mitotic spindle, resulting in an arrest of dividing cells at the metaphase stage. It binds to microtubule with a K i of 85 nM. Uses: Scientific research. Group: Natural products. Alternative Names: Leurocristine sulfate; NSC-67574 sulfate; 22-Oxovincaleukoblastine sulfate. CAS No. 2068-78-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-N0488. | |
| Vindesine sulfate | Vindesine sulfate is a potent tubulin inhibitor with an K i of 0.110 μM. Vindesine sulfate shows anti-proliferation effect in vitro. Vindesine sulfate shows antitumor effect in vivo [1]. Uses: Scientific research. Group: Natural products. CAS No. 59917-39-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129071. | |
| Vindoline | Vindoline, a vinca alkaloid extracted from the leaves of Catharanthus roseus , weakly inhibits tubulin self-assembly [1]. Uses: Scientific research. Group: Natural products. CAS No. 2182-14-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 20 mg. Product ID: HY-N0687. | |
| Vinorelbine ditartrate | Vinorelbine (ditartrate) is an anti-mitotic agent which inhibits the proliferation of Hela cells with IC 50 of 1.25 nM. Uses: Scientific research. Group: Natural products. Alternative Names: KW-2307; Nor-5'-anhydrovinblastine ditartrate. CAS No. 125317-39-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-12053A. | |
| Vinpocetine | Vinpocetine (Ethyl apovincaminate) is a derivative of the alkaloid Vincamine that blocks voltage-gated Na + channels. The IC 50 value of Vinpocetine on direct IKK inhibition in the cell-free system is 17.17 μM. Vinpocetine is a phosphodiesterase (PDE) inhibitor and inhibits NF-κB -dependent inflammatory responses by directly targeting IκB kinase complex (IKK) , and has been widely used for the treatment of cerebrovascular disorders [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Ethyl apovincaminate. CAS No. 42971-09-5. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-13295. | |
| Vinyl-L-NIO hydrochloride | Vinyl-L-NIO hydrochloride is a potent nitric oxide synthase (NOS) inhibitor. Vinyl-L-NIO hydrochloride inhibits the activity of NOS, reducing the production of nitric oxide [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 728944-69-2. Pack Sizes: 5 mg. Product ID: HY-130579. | |
| Violuric acid | Violuric acid is a redox mediator used in the laccase system. The violuric acid assay is a method to ascertain that the high-redox potential of laccase is not lost during directed evolution [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 87-39-8. Pack Sizes: 1 g; 5 g; 10 g. Product ID: HY-W097009. | |
| VIP(Guinea pig) | VIP Guinea pig (Vasoactive intestinal peptide), a trophic and mitogenic factor, stimulates growth in whole cultured embryos. VIP Guinea pig functions as a simple gastrointestinal hormone and suggest a possible neurotransmitter function [1] [2]. Uses: Scientific research. Group: Peptides. Alternative Names: Vasoactive Intestinal Peptide, guinea pig. CAS No. 96886-24-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1015. | |
| Vipivotide tetraxetan | Vipivotide tetraxetan (PSMA-617) is a high potent prostate-specific membrane antigen (PSMA) inhibitor, with a K i of 0.37 nM. Vipivotide tetraxetan (PSMA-617) is designed consisting of three components: the pharmacophore Glutamate-urea-Lysine, the chelator DOTA able to complex both 68Ga or 177Lu, and a linker connecting these two entities. Glutamate-urea-Lysine is the selective pharmacophore to bind to prostate specific membrane antigen. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PSMA-617. CAS No. 1702967-37-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-117410. | |
| Virginiamycin M1 | Virginiamycin M1 (Pristinamycin IIA; Ostreogrycin A), produced by Streptomyces virginiae , is an polyunsaturated macrocyclic lactone antibiotic and acts as a component of Virginiamycin (HY-112665) [1]. Virginiamycin M1 alone is against Staphylococcus aureus with a MIC of 0.25 μg/mL. Uses: Scientific research. Group: Natural products. Alternative Names: Pristinamycin IIA; Ostreogrycin A. CAS No. 21411-53-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N6686. | |
| Virodhamine | Virodhamine is an endocannabinoid, it regulates neurotransmission by activating the cannabinoid (CB) receptors. Virodhamine is an antagonist of CB1 receptor and an agonist of CB2 receptor. Virodhamine induces megakaryocytic differentiation by triggering MAPK signaling and ROS production. Virodhamine can be used for the research of various neurological disorders such as Alzheimer's and Parkinson's diseases [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 287937-12-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116418. | |
| Virstatin | Virstatin inhibits the pili system synthesis and prevents A. baumannii biofilm formation. Virstatin also inhibits dimerization of the transcriptional activator ToxT [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 88909-96-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-127041. | |
| Visilizumab | Visilizumab (Anti-Human CD3E Recombinant Antibody) is a humanized low-Fc receptor binding anti-CD3 monoclonal IgG2 antibody. Visilizumab can be used for ulcerative colitis and Crohn's disease research [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-Human CD3E Recombinant Antibody; HuM291. CAS No. 219716-33-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99332. | |
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