MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Raf inhibitor 1 | Raf inhibitor 1 is a potent Raf kinase inhibitor with Kis of 1 nM, 1 nM, and 0.3 nM for B-RafWT, B-RafV600E, and C-Raf, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1093100-40-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14177. |  |
| Raf inhibitor 2 | Raf inhibitor 2 is a potent raf kinase (IC 50 <1.0 μM) inhibitor, compound 32, extracted from patent EP1003721B1. Raf inhibitor 2 can be used for cancer research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 220904-99-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-109574. | |
| Rafoxanide | Rafoxanide is a poent, orally active halogenated salicylaniline agent with antiparasitic activity. Rafoxanide interferes with energy metabolism in trematodes by uncoupling oxidative phosphorylation. Rafoxanide is also found to be a potent inhibitor of the BRAF V600E mutant protein , which is important in colorectal cancer. Rafoxanide can be used for the control of infestation with Hemonchus species or Fasciola species in sheep and cattle as well as Oestrus ovis in sheep. Rafoxanide can also be used for cancer research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 22662-39-1. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-17598. | |
| RAGE 229 | RAGE 229 is an orally active ctRAGE-DIAPH1 inhibitor. RAGE 229 can inhibit the intracellular RAGE signaling by inhibiting the interaction between the cytoplasmic tail of RAGE(ctRAGE) and Diaphanous-1(DIAPH1)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2143072-85-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147329. | |
| RAGE antagonist peptide | RAGE antagonist peptide is an advanced glycation end products (RAGE) antagonist. RAGE antagonist peptide prevents RAGE from binding with several of its most important ligands, including HMGB-1, S100P, and S100A4. RAGE antagonist peptide (RAP) possesses anti-tumor and anti-inflammatory activities [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 1092460-91-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P2268. | |
| Raleukin | Raleukin (AMG-719) is a recombinant, nonglycosylated human interleukin-1 receptor (IL-1R) antagonist. Raleukin significantly reduces neutrophil accumulation in blood vessels and brain infarct volume as well as improves motor coordination performance in ischemic stroke mice model. Anakinra can be used to study chronic inflammatory disorders like rheumatoid arthritis and cardiovascular recurrence post-myocardial infarction[1][2][3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Kineret; Anakinra. CAS No. 143090-92-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-108841. | |
| Ralfinamide | Ralfinamide (FCE-26742A) is an orally available Na + blocker derived from α-aminoamide, with function of suppressing pain [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FCE-26742A. CAS No. 133865-88-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-101437. | |
| Ralimetinib dimesylate | Ralimetinib dimesylate (LY2228820 dimesylate) is a selective, ATP-competitive inhibitor of p38 MAPK ?/? with IC50s of 5.3 and 3.2 nM, respectively. Ralimetinib (LY2228820) selectively inhibits phosphorylation of MK2 (Thr334), with no effect on phosphorylation of p38a MAPK, JNK, ERK1/2, c-Jun, ATF2, or c-Myc. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY2228820 dimesylate. CAS No. 862507-23-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13241. | |
| Ralinepag | Ralinepag is a potent, orally bioavailable and non-prostanoid prostacyclin (IP) receptor agonist, with EC 50 s of 8.5 nM, 530 nM and 850 nM for human and rat IP receptor and human DP1 receptor, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: APD811. CAS No. 1187856-49-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16751. | |
| Ralometostat | TNG908 is a MTAP synergistic PRMT5 inhibitor. TNG908 crosses the blood-brain barrier and is orally active. TNG908 could be used in cancer research[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TNG908. CAS No. 2760481-53-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148419. | |
| Raloxifene | Raloxifene (Keoxifene) is a benzothiophene-derived selective estrogen receptor modulator (SERM). Raloxifene has estrogen-agonistic effects on bone and lipids and estrogen-antagonistic effects on the breast and uterus. Raloxifene is used for breast cancer and osteoporosis research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Keoxifene; LY156758 free base; LY139481. CAS No. 84449-90-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-13738. | |
| Raloxifene hydrochloride | Raloxifene hydrochloride (Keoxifene hydrochloride) is a second generation selective and orally active estrogen receptor modulator. Raloxifene hydrochloride produces estrogen-agonistic effects on bone and lipid metabolism and estrogen-antagonistic effects on uterine endometrium and breast tissue [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Keoxifene hydrochloride; LY156758; LY139481 hydrochloride. CAS No. 82640-04-8. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-13738A. | |
| Raloxifene (hydrochloride) (Standard) | Raloxifene (hydrochloride) (Standard) is the analytical standard of Raloxifene (hydrochloride). This product is intended for research and analytical applications. Raloxifene hydrochloride (Keoxifene hydrochloride) is a second generation selective and orally active estrogen receptor modulator. Raloxifene hydrochloride produces estrogen-agonistic effects on bone and lipid metabolism and estrogen-antagonistic effects on uterine endometrium and breast tissue [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Keoxifene (hydrochloride)(Standard); LY156758(Standard); LY139481 (hydrochloride) (Standard). CAS No. 82640-04-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13738AR. | |
| (R)-(-)-α-Methylhistamine dihydrochloride | (R)-(-)-α-Methylhistamine dihydrochloride is a potent, selective and brain-penetrant agonist of H3 histamine receptor, with a K d of 50.3 nM [1] [2]. (R)-(-)-α-Methylhistamine dihydrochloride can enhance memory retention, attenuates memory impairment in rats [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 75614-89-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-W014941. | |
| (R)-(-)-α-Phellandrene | (R)-(-)-α-Phellandrene ((-)-α-Phellandrene) is an the (R)-(-)-stereoisomer of α-phellandrene. α-phellandrene is an orally active cyclic monoterpene that attenuates inflammatory response, and induces DNA damage [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: (-)-α-Phellandrene. CAS No. 4221-98-1. Pack Sizes: 1 mL. Product ID: HY-N9487. | |
| Raltegravir | Raltegravir is a potent integrase (IN) inhibitor, used to treat HIV infection. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-0518. CAS No. 518048-05-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-10353. | |
| Raltegravir potassium | Raltegravir (MK 0518) potassium is a potent integrase (IN) inhibitor, used to treat HIV infection. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK 0518 potassium. CAS No. 871038-72-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10353A. | |
| Raltitrexed | Raltitrexed is an antimetabolite agent used in chemotherapy, acting by inhibiting thymidylate synthase. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ZD1694; D1694; ICI-D1694. CAS No. 112887-68-0. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10821. | |
| Raludotatug | Raludotatug is a humanized immunoglobulin G1-kappa, anti-CDH6 monoclonal antibody. Raludotatug is an antineoplastic [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2610074-56-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990028. | |
| Raludotatug Deruxtecan | Raludotatug Deruxtecan (DS-6000) is a novel antibody conjugate (ADC) targeting CDH6. Raludotatug Deruxtecan is conjugated with Raludotatug (HY-P990028) and Deruxtecan (HY-13631E). Raludotatug Deruxtecan can be used in the research of ovarian cancer and renal cancer. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R-DXd; DS-6000. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-164734. | |
| Ramatroban | Ramatroban is a selective thromboxane A 2 ( TxA 2 , IC 50 =14 nM) antagonist, which also antagonizes CRTH2 ( IC 50 =113 nM) by inhibiting PGD 2 binding. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY u3405. CAS No. 116649-85-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0745. | |
| Ramelteon | Ramelteon is a potent, highly selective, and orally active agonist of MT1/MT2 with Ki values of 14 and 112 pM, respectively. Ramelteon has the potential for the research of insomnia. Ramelteon consistently reduces sleep onset after long-term treatment, with no next-morning residual effects or rebound insomnia or withdrawal symptoms upon discontinuation [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TAK-375. CAS No. 196597-26-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-A0014. | |
| (R)-Aminocarnitine | (R)-Aminocarnitine (Emeriamine) is a fatty acid oxidation inhibitor. (R)-Aminocarnitine reduces hyperglycaemia and ketosis. (R)-Aminocarnitine can be used in the study of metabolic diseases [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Emeriamine. CAS No. 98063-21-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-126221A. | |
| (R)-(+)-Aminoglutethimide | (R)-(+)-Aminoglutethimide is a potent and orally active aromatase inhibitor. (R)-(+)-Aminoglutethimide has the potential for the research of breast cancer [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: d-Aminoglutethimide. CAS No. 55511-44-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W392925. | |
| Ramipril | Ramipril (HOE-498) is an angiotensin-converting enzyme (ACE) inhibitor with IC 50 of 5 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HOE-498. CAS No. 87333-19-5. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-B0279. | |
| (R)-Amlodipine-d4 | (R)-Amlodipine-d 4 is the deuterium labeled (R)-Amlodipine[1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 1346616-97-4. Pack Sizes: 500 μg; 1 mg. Product ID: HY-B0317DS. | |
| Ramoplanin | Ramoplanin is a broad-spectrum lipoglycodepsipeptide antibiotic derived from the Actinoplanes spp with with activity against gram-positive bacteria [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 76168-82-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129034. | |
| Ramosetron Hydrochloride | Ramosetron (YM060 free base) Hydrochloride is an orally active 5-HT 3 antagonist that improves dysphoria, interference with activity and food avoidance. Ramosetron Hydrochloride is promising for research of irritable bowel syndrome with diarrhea [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: YM060. CAS No. 132907-72-3. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B0595. | |
| Ramucirumab (anti-VEGFR) | Ramucirumab (anti-VEGFR) is a human VEGFR-2 antagonist for the treatment of solid tumors. Ramucirumab (anti-VEGFR) is a recombinant human immunoglobulin G1 monoclonal antibody that binds to the extracellular binding domain of VEGFR-2 and prevents the binding of VEGFR ligands: VEGF-A, VEGF-C, and VEGF-D. Ramucirumab (anti-VEGFR) is also an angiogenesis inhibitor [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 947687-13-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P9920A. | |
| Ranibizumab (anti-VEGF) | Ranibizumab (RG-6321) (anti-VEGF) is a humanized anti-VEGF monoclonal antibody fragment and can recognize all VEGF-A isoforms (VEGF110, VEGF121, and VEGF165) [1]. Ranibizumab (anti-VEGF) slows vision loss in vivo and is used for wet age-related macular degeneration (AMD) research [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: RG-6321 (anti-VEGF). CAS No. 347396-82-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9951A. | |
| Ranitidine | Ranitidine is a potent, selective and orally active histamine H2-receptor antagonist with an IC 50 of 3.3 μM that inhibits gastric secretion. Ranitidine is a weak inhibitor of CYP2C19 and CYP2C9 [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 66357-35-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-B0693. | |
| Ranitidine-d6 hydrochloride | Ranitidine-d 6 (hydrochloride) is the deuterium labeled Ranitidine hydrochloride. Ranitidine hydrochloride is a potent, selective and orally active histamine H2-receptor antagonist with an IC50 of 3.3 μM that inhibits gastric secretion. Ranitidine hydrochloride is a weak inhibitor of CYP2C19 and CYP2C9[1][2]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 1185238-09-8. Pack Sizes: 1 mg. Product ID: HY-B0281AS. | |
| Ranitidine hydrochloride | Ranitidine hydrochloride is a potent, selective and orally active histamine H2-receptor antagonist with an IC 50 of 3.3 μM that inhibits gastric secretion. Ranitidine hydrochloride is a weak inhibitor of CYP2C19 and CYP2C9 [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 66357-59-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0281A. | |
| Ranolazine | Ranolazine (CVT 303) is an anti-angina drug that achieves its effects by inhibiting the late phase of inward sodium current ( I Na and I Kr with IC 50 values of 6 μM and 12 μM, respectively) without affecting heart rate or blood pressure (BP) [1] [2]. Ranolazine is also a partial fatty acid oxidation (FAO) inhibitor [3]. Antianginal agent. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CVT 303; RS 43285-003. CAS No. 95635-55-5. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg. Product ID: HY-B0280. | |
| Ranolazine dihydrochloride | Ranolazine dihydrochloride (CVT 303 dihydrochloride) is an anti-angina agent that achieves its effects by inhibiting the late phase of inward sodium current ( I Na and I Kr with IC 50 values of 6 μM and 12 μM, respectively) without affecting heart rate or blood pressure (BP) [1] [2]. Ranolazine dihydrochloride is also a partial fatty acid oxidation inhibitor [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CVT 303 dihydrochloride; RS 43285. CAS No. 95635-56-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg; 1 g; 5 g. Product ID: HY-17401. | |
| Rapacuronium bromide | Rapacuronium bromide (Org 9487), a non-depolarizing neuromuscular blocker, is an allosteric modulator of muscarinic acetylcholine receptor (mAChR) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Org 9487. CAS No. 156137-99-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16423. | |
| RapaLink-1 | RapaLink-1, the third-generation bivalent mTOR inhibitor, combines Rapamycin (HY-10219) with MLN0128 (HY-13328, a second-generation mTOR kinase inhibitor) by an inert chemical linker. RapaLink-1 shows better efficacy than Rapamycin or mTOR kinase inhibitors (TORKi), potently blocking cancer-derived, activating mutants of mTOR. RapaLink-1 can cross the blood-brain barrier. RapaLink-1 binding to FKBP12 results in targeted and durable inhibition of mTORC1. RapaLink-1 plays an antithrombotic role in antiphospholipid syndrome by improving autophagy. Anticancer activity[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1887095-82-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-111373. | |
| Rapamycin | Rapamycin (Sirolimus; AY 22989) is a potent and specific mTOR inhibitor with an IC 50 of 0.1 nM in HEK293 cells. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1 [1]. Rapamycin is an autophagy activator, an immunosuppressant [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Sirolimus; AY-22989. CAS No. 53123-88-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g; 2 g; 5 g. Product ID: HY-10219. | |
| Rapamycin-d3 | Rapamycin-d 3 is the deuterium labeled Rapamycin. Rapamycin is a potent and specific mTOR inhibitor with an IC 50 of 0.1 nM in HEK293 cells. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1. Rapamycin is an autophagy activator, an immunosuppressant [1] [2]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: Sirolimus-d3; AY-22989-d3. CAS No. 392711-19-2. Pack Sizes: 500 μg; 1 mg. Product ID: HY-10219S. | |
| Rapastinel Trifluoroacetate | Rapastinel Trifluoroacetate (GLYX-13 Trifluoroacetate) is an NMDA receptor modulator with glycine-site partial agonist properties. Rapastinel Trifluoroacetate has the potential for major depressive disorder treatment. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GLYX-13 Trifluoroacetate. CAS No. 1435786-04-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-16728B. | |
| Raphin1 | Raphin1 is an orally bioavailable, selective inhibitor of the regulatory phosphatase PPP1R15B (R15B). Raphin1 binds strongly to the R15B-PP1c holophosphatase (Kd=33 nM), and shows ~30-fold selective in binding R15B-PP1c over R15A-PP1c. Raphin1 crosses the blood-brain barrier, and reduces organismal and molecular deficits in a mouse model of a protein misfolding disease[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2022961-17-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123960. | |
| Raptinal | Raptinal, a agent that directly activates caspase-3, initiates intrinsic pathway caspase-dependent apoptosis. Raptinal is able to rapidly induce cancer cell death by directly activating the effector caspase-3, bypassing the activation of initiator caspase-8 and caspase-9[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1176-09-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-121320. | |
| Rasagiline | Rasagiline (R-AGN1135) is a highly potent selective irreversible mitochondrial monoamine oxidase ( MAO ) inhibitor with IC 50 s of 4.43 nM and 412 nM for rat brain MAO B and A activity, respectively [1]. Rasagiline is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (R)-AGN1135; TVP1012. CAS No. 136236-51-6. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 250 mg. Product ID: HY-14605A. | |
| Rasagiline mesylate | Rasagiline (R-AGN1135) mesylate is a highly potent selective irreversible mitochondrial monoamine oxidase ( MAO ) inhibitor with IC 50 s of 4.43 nM and 412 nM for rat brain MAO B and A activity, respectively [1]. Rasagiline (mesylate) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (R)-AGN1135 mesylate; TVP1012 mesylate. CAS No. 161735-79-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14605. | |
| Rasburicase | Rasburicase is a recombinant urate oxidase and a hyperuricemia inhibitor. Rasburicase converts uric acid into allantoin, making it easier to be cleared by the kidneys and improving the elevated level of uric acid in the blood [1]. Uses: Scientific research. Group: Natural products. CAS No. 134774-45-1. Pack Sizes: 1 mg. Product ID: HY-108844. | |
| Raspberry ketone | Raspberry ketone is a major aromatic compound of red raspberry, widely used as a fragrance in cosmetics and as a flavoring agent in foodstuff; also shows PPAR-α agonistic activity. Uses: Scientific research. Group: Natural products. Alternative Names: Frambione; 4-(4-Hydroxyphenyl)-2-butanone. CAS No. 5471-51-2. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-N1426. | |
| Rat CGRP-(8-37) | Rat CGRP-(8-37) (VTHRLAGLLSRSGGVVKDNFVPTNVGSEAF) is a highly selective CGRP receptor antagonist. Uses: Scientific research. Group: Peptides. CAS No. 129121-73-9. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-P0209. | |
| (R)-(+)-Atenolol | (R)-(+)-Atenolol is the less active enantiomer of the (R,S)-atenolol. (R,S)-atenolol is a β-adrenergic receptor antagonist [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 56715-13-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-B2111. | |
| Rat IgG2a kappa, Isotype Control | Rat IgG2a kappa, Isotype Control is a monoclonal antibody derived from rats, representing the immunoglobulin G2a (IgG2a) subclass with a kappa light chain. Rat IgG2a kappa, Isotype Control exhibits high efficiency in inducing K cell mediated cytotoxicity. Rat IgG2a kappa, Isotype Control is utilized in research investigating the roles of different immunoglobulin subclasses in tumor immunology[1]. Uses: Scientific research. Group: Inhibitory antibodies. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990679. | |
| Rat IgG2b kappa, Isotype Control | Rat IgG2b kappa, Isotype Control is a rat IgG2b ? antibody isotype control that can be used to exclude or reduce false positive results caused by nonspecific binding[1]. Uses: Scientific research. Group: Inhibitory antibodies. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P990682. | |
| Rauwolscine | Rauwolscine is a selective α2-adrenoceptor antagonist that inhibits tumor growth and induces apoptosis [1]. Uses: Scientific research. Group: Natural products. Alternative Names: α-Yohimbine; Corynanthidine; Isoyohimbine. CAS No. 131-03-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-12710. | |
| Rauwolscine hydrochloride | Rauwolscine hydrochloride is a potent and specific α2 adrenergic receptor antagonist with a K i of 12 nM. Uses: Scientific research. Group: Natural products. Alternative Names: α-Yohimbine hydrochloride; Corynanthidine hydrochloride; Isoyohimbine hydrochloride. CAS No. 6211-32-1. Pack Sizes: 1 mg. Product ID: HY-12710A. | |
| Ravagalimab | Ravagalimab (ABBV-323) is a CD40 antagonist ( EC 50 : 3.7?nM). Ravagalimab can be used for research of Crohn's disease [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ABBV-323. CAS No. 2050816-56-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99821. | |
| Ravidasvir hydrochloride | Ravidasvir hydrochloride (PPI-668 hydrochloride) is a pan-genotypic inhibitor for hepatitis C virus (HCV) NS5A protein. Ravidasvir hydrochloride inhibits the replication of HCV, with EC 50 of 0.12, 0.01 and 1.14 nM, for HCV gt-1a, gt-1b, and gt-3a replicons, respectively. Ravidasvir hydrochloride exhibits good pharmacokinetic characters in rats [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PPI-668 hydrochloride. CAS No. 1303533-81-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124191. | |
| Ravoxertinib | Ravoxertinib (GDC-0994) is an orally active ERK kinase inhibitor with an IC50 of 6.1 nM and 3.1 nM for ERK1 and ERK2, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GDC-0994. CAS No. 1453848-26-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15947. | |
| Ravuconazole | Ravuconazole (BMS-207147;ER-30346) is an orally available triazole antifungle agent that potently inhibits a wide range of fungi. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-207147; ER-30346. CAS No. 182760-06-1. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-14272. | |
| Ravulizumab | Ravulizumab (ALXN1210) is a humanized monoclonal antibody that specifically binds with high affinity to the human complement protein C5. Ravulizumab can be used for the research of paroxysmal nocturnal hemoglobinuria, atypical hemolytic uremic syndrome, and myasthenia gravis [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ALXN1210. CAS No. 1803171-55-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99365. | |
| Raxibacumab | Raxibacumab (ABthrax) is a human IgG1 monoclonal antibody against Bacillus anthracis protective antigen ( PA ). Raxibacumab blocks the toxins deleterious effects by preventing binding of the protective antigen component of the anthrax toxin to its receptors in host cells, thereby blocking the toxins deleterious effects. Raxibacumab can be used for anti-anthrax research [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ABthrax. CAS No. 565451-13-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9957. | |
| (R)-Azetidine-2-carboxylic acid | (R)-Azetidine-2-carboxylic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). (R)-Azetidine-2-carboxylic acid is also a alkyl chain-based PROTAC linker that can be. Uses: Scientific research. Group: Signaling pathways. CAS No. 7729-30-8. Pack Sizes: 1 g; 5 g. Product ID: HY-W017755. | |
| Razoxane | Razoxane (ICRF 159) is an antiangiogenic topoisomerase II inhibitor, can be used for the research of renal cell carcinoma (RCC) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ICRF 159. CAS No. 21416-67-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119425. | |
| Razuprotafib | Razuprotafib (AKB-9778) is a potent and selective inhibitor of the catalytic activity of VE-PTP (vascular endothelial protein tyrosine phosphatase) with an IC50of 17 pM. Razuprotafib promotes TIE2 activation, enhances ANG1-induced TIE2 activation, and stimulates phosphorylation of signaling molecules in the TIE2 pathway, including AKT, eNOS, and ERK. Razuprotafib inhibits the structurally related phosphatase PTP1B with an IC50 of 780 nM. Razuprotafib shows excellent selectivity for VE-PTP versus a variety of phosphatases, with the exception of HPTP? (IC50=36 pM) and HPTP? (100 pM)[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AKB-9778. CAS No. 1008510-37-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109041. | |
| RB-3 | RB-3, a polycomb repressive complex 1 (PRC1) inhibitor, binds to RING1B-BMI1f, with a Kd of 2.8 ?M[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2396639-11-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139514. | |
| (R)-Baclofen | (R)-Baclofen (Arbaclofen) is a selective GABAB receptor agonist [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Arbaclofen; STX209. CAS No. 69308-37-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-17354. | |
| (R)-BAY1238097 | (R)-BAY1238097 is the R-isomer with lower activity of BAY1238097. BAY1238097 is a potent and selective inhibitor of BET binding to histones and has strong anti-proliferative activity in different AML (acute myeloid leukemia) and MM (multiple myeloma) models through down-regulation of c-Myc levels and its downstream transcriptome [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1564269-85-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-112316A. | |
| (R)-BAY-85-8501 | (R)-BAY-85-8501 is the less active Enantiomer of BAY-85-8501. BAY-85-8501 is a selective and potent inhibitor of Human Neutrophil Elastase (HNE) , with an IC 50 of 65 pM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2446175-39-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19908B. | |
| RBC10 | RBC10 is an anti-cancer agent. RBC10 inhibits the binding of Ral to its effector RALBP1. RBC10 also inhibits Ral-mediated cell spreading of murine embryonic fibroblasts and anchorage-independent growth of human cancer cell lines [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 362503-73-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123464. | |
| RBC6 | RBC6 is an inhibitor of GTPases RalA. RBC6 inhibits binding of Ral to its effector RALBP1. RBC6 also inhibits Ral-mediated cell spreading of murine embryonic fibroblasts, as well as anchorage-independent growth of human cancer celllines [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 381186-64-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125987. | |
| RBC8 | RBC8 is a selective and allosteric RALA and RALB inhibitor. RBC8 stabilizes the inactive GDP-bound state of Ral, preventing its activation. RBC8 promotes the phosphorylation of proteins related to the MAPK/JNK pathway. RBC8 has the activity of inhibiting tumor cell proliferation, migration and invasion. RBC8 is used in the study of various cancers such as lung cancer, gastric cancer, and multiple myeloma [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 361185-42-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12873. | |
| Rbin-2 | Rbin-2 is a potent, reversible and selective inhibitor of Midasin (Mdn1), an enzyme belonging to the AAA+ (ATPases associated with diverse cellular activities) protein family. Rbin-2 inhibits eukaryotic ribosome biogenesis and is a powerful probe for the eukaryotic ribosome assembly [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2032282-97-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100817. | |
| (R)-BINAP | (R)-BINAP is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 76189-55-4. Pack Sizes: 5 g; 10 g. Product ID: HY-W017757. | |
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