MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Vismodegib | Vismodegib (GDC-0449) is an orally active hedgehog pathway inhibitor with an IC 50 of 3 nM. Vismodegib also inhibits P-gp , ABCG2 with IC 50 values of 3.0 μM and 1.4 μM, respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GDC-0449. CAS No. 879085-55-9. Pack Sizes: 10 mM * 1 mL; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10440. |  |
| Visnagin | Visnagin, an antioxidant furanocoumarin derivative, possess anti-inflammatory and analgesic properties. Visnagin has substantial potential to prevent Cerulein induced acute pancreatitis (AP). Visnagin possess promising vasodilator effects in vascular smooth muscles [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 82-57-5. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-N1082. | |
| Vistusertib | Vistusertib (AZD2014) is an ATP competitive mTOR inhibitor with an IC 50 of 2.81 nM. AZD2014 inhibits both mTORC1 and mTORC2 complexes. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AZD2014. CAS No. 1009298-59-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15247. | |
| Visugromab | Visugromab (CTL-002) is a GDF-15 neutralizing IgG4 mAb. Visugromab has synergistic anticancer activity with the anti-PD1 antibody Nivolumab (HY-P9903) and can effectively act on PD-1/PD-L1 relapsed/refractory metastatic solid tumors [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: CTL-002. CAS No. 2556646-63-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99100. | |
| Vitamin A | Vitamin A (Vitamin A1) is an endogenous metabolite. Uses: Scientific research. Group: Natural products. Alternative Names: Vitamin A1; all-trans-Retinol. CAS No. 68-26-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-B1342. | |
| Vitamin B12 | Vitamin B12 is a vitamin. Vitamin B12 plays a key role in the normal functioning of the brain and nervous system, and for the formation of blood. Vitamin B12 is beneficial for many inflammatory diseases and also provides protection in oxidative-stress-associated pathologies [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Cyanocobalamin. CAS No. 68-19-9. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-B0315. | |
| Vitamin B1 monophosphate chloride | Vitamin B1 monophosphate (Thiamine monophosphate) chloride is a source of vitamin B1 and can be used in food supplements to enhance nutrition [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Thiamine monophosphate chloride. CAS No. 532-40-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-B1701. | |
| Vitamin B6 | Vitamin B6 is a potent antioxidant. Vitamin B6 is a suitable cofactor for many biochemical processes due to its water solubility and high reactivity when phosphorylated. Vitamin B6 is essential for the cellular metabolism and well-being of all living organisms [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 8059-24-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-150525. | |
| Vitamin D2 | Vitamin D2 (Ergocalciferol), drived from plant sources or dietary supplements, could be used as supplement of Vitamin D [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Ergocalciferol; Calciferol; Ercalciol. CAS No. 50-14-6. Pack Sizes: 500 mg; 1 g; 5 g; 10 g. Product ID: HY-76542. | |
| Vitamin D2-d3 | Vitamin D2-d 3 (Ergocalciferol-d 3 ) is the deuterium labeled vitamin D2. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: Ergocalciferol-d3; Calciferol-d3; VD2-d3. CAS No. 1217448-46-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-15330. | |
| Vitamin D3 | Vitamin D3 (Cholecalciferol; Colecalciferol) is a naturally occuring form of vitamin D. Vitamin D3 induces cell differentiation and prevents proliferation of cancer cells. Uses: Scientific research. Group: Natural products. Alternative Names: Cholecalciferol; Colecalciferol. CAS No. 67-97-0. Pack Sizes: 100 mg; 1 g; 5 g. Product ID: HY-15398. | |
| Vitamin D3-d3 | Vitamin D3-d 3 is the deuterium labeled Vitamin D3. Vitamin D3 (Cholecalciferol; Colecalciferol) is a naturally occuring form of vitamin D. Vitamin D3 induces cell differentiation and prevents proliferation of cancer cells. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: Cholecalciferol-d3; Colecalciferol-d3. CAS No. 80666-48-4. Pack Sizes: 100 μg; 1 mg. Product ID: HY-15398S3. | |
| Vitamin D4 | Vitamin D4 (22-Dihydroergocalciferol) is a Vitamin D derived from fungi. The precursor of Vitamin D4 is 22,23-dihydroergosterol [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 22-Dihydroergocalciferol. CAS No. 511-28-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-75958. | |
| Vitamin K | Vitamin K, the blood-clotting vitamin, is important for the function of numerous proteins within the body, such as the coagulation factors, osteocalcin and matrix-Gla protein. Uses: Scientific research. Group: Natural products. CAS No. 12001-79-5. Pack Sizes: 5 mg; 10 mg; 50 mg. Product ID: HY-B2172. | |
| Vitamin K1 | Vitamin K1 a naturally occurring vitamin required for blood coagulation and bone and vascular metabolism. Uses: Scientific research. Group: Natural products. Alternative Names: Phylloquinone; Phytomenadione. CAS No. 84-80-0. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-N0684. | |
| Vitamin K1 2,3-epoxide | Vitamin K1 2,3-epoxide is an inactive metabolite form of Vitamin K1 (HY-N0684), which is reduced to active vitamin by microsomal epoxide reductase in the vitamin K epoxide cycle. Vitamin K1 2,3-epoxide is involved in blood clotting [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 25486-55-9. Pack Sizes: 1 mg. Product ID: HY-113164. | |
| Vitamin U chloride | Vitamin U (S-Methylmethionine sulfonium) chloride is an orally active anti-ulcer agent with antioxidant activity. Vitamin U inhibits adipocyte differentiation. Vitamin U promotes skin wound healing.Vitamin U can be used in the research of gastrointestinal ulceration [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. Alternative Names: S-Methylmethionine sulfonium chloride. CAS No. 1115-84-0. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-N2551. | |
| Vitexin | Vitexin is a c-glycosylated flavone, and is found in various medicinal plants species such as Trigonella foenum-graecum Linn. Vitexin has a wide range of pharmacological effects, including anti-oxidant, anti-cancer, anti-inflammatory, anti-hyperalgesic, and neuroprotective effects [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 3681-93-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0013. | |
| Vitexin-2'-O-rhamnoside | Vitexin-2"-O-rhamnoside, a main flavonoid glycoside of the leaves of Cratagus pinnatifida Bge, contributes to the protection against H 2 O 2 -mediated oxidative stress damage and has potential to treat cardiovascular system diseases [1]. Uses: Scientific research. Group: Natural products. CAS No. 64820-99-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N0534. | |
| Vitexin-4''-O-glucoside | Vitexin-4''-O-glucoside is a kind of flavonoid fraction from the leaves of Crataegus pinnatifida [1]. Uses: Scientific research. Group: Natural products. Alternative Names: 4''-O-Glucosylvitexin. CAS No. 178468-00-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N5073. | |
| Vixarelimab | Vixarelimab (KPL-716) is a human anti-oncostatin M ( OSM ) monoclonal antibody that binds to the beta chain of the OSM receptor and inhibits IL-31 and OSM signalling. Vixarelimab can be used in studies of inflammatory skin diseases such as atopic dermatitis and itchy nodular rash [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: KPL-716. CAS No. 2243320-83-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99519. | |
| VK-2019 | VK-2019 is an oral active, selective EBNA1 ((Epstein-Barr Nuclear Antigen 1) inhibitor and can be used for study of EBV-associated carcinomas [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2044520-06-9. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-W725179. | |
| VK-28 | VK-28, a brain-permeable iron chelator, inhibits both basal and Fe/ascorbate-induced mitochondrial membrane lipid peroxidation, with an IC 50 of 12.7 μM. VK-28 exhibits significant neuroprotective effects on ICV-6-OHDA. VK-28 can be used for the research of Parkinsons disease and other neurodegenerative diseases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 312611-92-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-W686216. | |
| VKGILS-NH2 | VKGILS-NH2 is a reversed amino acid sequence control peptide for SLIGKV-NH2 (protease-activated receptor 2 (PAR2) agonist). VKGILS-NH2 has no effect on DNA synthesis in cells [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 942413-05-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1310. | |
| VLX600 | VLX600 is an iron-chelating inhibitor of oxidative phosphorylation (OXPHOS). VLX600 causes mitochondrial dysfunction and induces a strong shift to glycolysis. VLX600 displays selective cytotoxic activity against malignant cell and induces autophagy. Anticancer activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 327031-55-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-12406. | |
| Voacamine | Voacamine, an indole alkaloid, exhibits potent cannabinoid CB1 receptor antagonistic activity [1]. Voacamine also inhibits P-glycoprotein ( P-gp ) action in multidrug-resistant tumor cells [1]. Uses: Scientific research. Group: Natural products. CAS No. 3371-85-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N6932. | |
| Voacangine | Voacangine is an antagonist for TRPV1 and TRPM8 but as an agonist for TRPA1 ( EC 50 =8 μM). Voacangine competitively blockes capsaicin binding to TRPV1 ( IC 50 =50 μM). Voacangine competitively inhibits the binding of menthol to TRPM8 ( IC 50 =9 μM) and it shows noncompetitive inhibition against icilin ( IC 50 =7 μM). Voacangine selectively abrogates chemical agonist-induced TRPM8 activation and did not affect cold-induced activation. Voacangine is an alkaloid isolated from the root bark of Voacanga africana [1]. Uses: Scientific research. Group: Natural products. CAS No. 510-22-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N7536. | |
| Vobarilizumab | Vobarilizumab (ALX-0061) is a humanized bispecific anti- IL-6R and anti-human serum albumin (ALB) monoclonal antibody (mAb) ( K d : 0.19 pM). Vobarilizumab consists of an anti-IL-6R domain and an anti-human serum albumin domain. Vobarilizumab can be used in the research of inflammatory autoimmune diseases, such as rheumatoid arthritis [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ALX-0061. CAS No. 1628814-88-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99385. | |
| Vobramitamab | Vobramitamab is a humanized B7-H3 monoclonal antibody (mAb). Vobramitamab conjugated with prodrug seco-DUBA (HY-132180A) via a cleavable linker, to form antibody-drug conjugate (ADC), the MGC018. MGC018 displays potent antitumor activity in preclinical tumor models of breast, ovarian, and lung cancer, as well as melanoma [1] [2] [3] [4]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: AEX-4089. CAS No. 2490556-50-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99101. | |
| Voclosporin | Voclosporin (ISAtx-247) is a calcineurin (PP2B) (CN) inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ISAtx-247. CAS No. 515814-01-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106638. | |
| Vofopitant | Vofopitant is potent tachykinin NK 1 receptor antagonist, with pK i s of 10.6, 9.5, and 9.8 for human, rat and ferret NK 1 receptor, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GR 205171. CAS No. 168266-90-8. Pack Sizes: 5 mg. Product ID: HY-12142. | |
| Vofopitant dihydrochloride | Vofopitant dihydrochloride (GR 205171A) is a potent, selective and orally available tachykinin neurokinin 1(NK1) receptor antagonist, inhibits [ 3 H]SP binding to the NK1 receptor with pK i values of 9.5 and 10.6 in rat and human membranes respectively, acts as a potential broad-spectrum anti-emetic agent [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GR 205171A. CAS No. 168266-51-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12143. | |
| Voglibose | Voglibose is an orally active alpha-glucosidase inhibitor that prevents the development of colorectal precancerous lesions induced by obesity and diabetes. Voglibose reduces oxidative stress in an inflammatory environment and inhibits the insulin-like growth factor/insulin-like growth factor-1 receptor (IGF/IGF-1R) functional axis [1]. Uses: Scientific research. Group: Natural products. CAS No. 83480-29-9. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B0025. | |
| Volagidemab | Volagidemab is an antagonistic glucagon receptor (GCGR) monoclonal antibody (mAb). Volagidemab can be used in the research of type 1 diabetes (T1D) [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: REMD-477; AMG-477. CAS No. 1233956-13-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99383. | |
| Volasertib | Volasertib (BI 6727) is an orally active, highly potent and ATP-competitive Polo-like kinase 1 (PLK1) inhibitor with an IC 50 of 0.87 nM. Volasertib inhibits PLK2 and PLK3 with IC 50 s of 5 and 56 nM, respectively. Volasertib induces mitotic arrest and apoptosis. Volasertib, a dihydropteridinone derivative, shows marked antitumor activity in multiple cancer models [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BI 6727. CAS No. 755038-65-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12137. | |
| Volinanserin | Volinanserin is a potent and selective antagonist of 5-HT 2 receptor , with a K i of 0.36 nM, and shows 300-fold selectivity for 5-HT 2 receptor over 5-HT 1c , alpha-1 and DA D 2 receptors. Volinanserin has antipsychotic activity. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MDL100907; M 100907. CAS No. 139290-65-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14940. | |
| Volixibat | Volixibat (SHP626) is a highly selective, minimally absorbed, and competitive apical sodium-dependent bile acid transporter (ASBT) inhibitor. Volixibat has potential for treatment for non-alcoholic steatohepatitis (NASH) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SHP626; LUM002. CAS No. 1025216-57-2. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-101190. | |
| Volociximab | Volociximab (M200) is a chimeric human/murine IgG4 antibody IIA1 targeting integrin α5β1 ( EC 50 =0.2 nM). Integrin α5β1 is a major fibronectin receptor involved in angiogenesis. Volociximab has antiangiogenic and antitumor activities and inhibits the proliferation of human umbilical vein vascular endothelial cells (HUVECs) [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: M200; Eos 200-4. CAS No. 558480-40-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99333. | |
| Vonafexor | Vonafexor (EYP001) is an orally active, non-steroidal and selective FXR agonist. Vonafexor shows significant HBsAg reduction when combined with Peg-IFN&alpha. Vonafexor can be used for anti- HBV research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EYP001. CAS No. 1192171-69-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109197. | |
| Vonoprazan | Vonoprazan (TAK-438 free base), a proton pump inhibitor (PPI), is a potent and orally active potassium-competitive acid blocker (P-CAB) , with antisecretory activity. Vonoprazan inhibits H + ,K + -ATPase activity in porcine gastric microsomes with an IC 50 of 19 nM at pH 6.5. Vonoprazan is developed for the research of acid-related diseases, such as gastroesophageal reflux disease and peptic ulcer disease. Vonoprazan can be used for eradication of Helicobacter pylori [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TAK-438 free base. CAS No. 881681-00-1. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg. Product ID: HY-100007. | |
| Vonoprazan Fumarate | Vonoprazan Fumarate (TAK-438), a proton pump inhibitor (PPI), is a potent and orally active potassium-competitive acid blocker (P-CAB) , with antisecretory activity. Vonoprazan Fumarate inhibits H + ,K + -ATPase activity in porcine gastric microsomes with an IC 50 of 19 nM at pH 6.5. Vonoprazan Fumarate is developed for the research of acid-related diseases, such as gastroesophageal reflux disease and peptic ulcer disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TAK-438. CAS No. 881681-01-2. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-15295. | |
| VO-Ohpic trihydrate | VO-Ohpic trihydrate is a highly potent inhibitor of PTEN with an IC 50 of 46±10 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 476310-60-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-13074. | |
| Vopratelimab | Vopratelimab (JTX-2011) is a humanized immunoglobulin G1-kappa agonist monoclonal antibody that pecifically binds to the Inducible CO-Stimulator of T cells (ICOS). Vopratelimab retains species cross-reactivity with affinities of 0.93 nM to hICOS, 0.46 nM to cynomolgus ICOS, 3.7 nM to rat ICOS, and 0.64 nM to mICOS. Vopratelimab has antitumor immune response [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: JTX 2011. CAS No. 2039148-04-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99382. | |
| Vorapaxar | Vorapaxar (SCH 530348), an antiplatelet agent, is a selective, orally active, and competitive thrombin receptor protease-activated receptor (PAR-1) antagonist ( K i =8.1 nM). Vorapaxar (SCH 530348) inhibits thrombin receptor-activating peptide (TRAP)-induced platelet aggregation in a dose-dependent manner [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SCH 530348. CAS No. 618385-01-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10119. | |
| Vorapaxar sulfate | Vorapaxar sulfate (SCH 530348 sulfate), an antiplatelet agent, is a selective, orally active, and competitive thrombin receptor protease-activated receptor (PAR-1) antagonist ( K i =8.1 nM). Vorapaxar sulfate inhibits thrombin receptor-activating peptide (TRAP)-induced platelet aggregation in a dose-dependent manner [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SCH 530348 sulfate. CAS No. 705260-08-8. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10119A. | |
| Vorasidenib | Vorasidenib (AG-881) is an orally available, brain penetrant second-generation dual mutant isocitrate dehydrogenases 1 and 2 (mIDH1/2) inhibitor. Vorasidenib (AG-881) exhibits nanomolar inhibition of (D)-2-hydroxyglutarate (D-2-HG), and the IC 50 ranges of 0.04~22 nM against IDH1 R132C, IDH1 R132G, IDH1 R132H and IDH1 R132S and 7~14 nM against IDH2 R140Q and 130 nM against IDH2 R172K. Vorasidenib can be used for the study of grade 2 astrocytoma or oligodendroglioma with a susceptible IDH1/2 mutation [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AG-881. CAS No. 1644545-52-7. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-104042. | |
| Voreloxin | Voreloxin (SNS-595; Vosaroxin; AG 7352) is a first-in-class topoisomerase II inhibitor that intercalates DNA and induces site-selective DNA DSB, G2 arrest, and apoptosis. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SNS-595; Vosaroxin; AG 7352. CAS No. 175414-77-4. Pack Sizes: 5 mg; 10 mg; 50 mg. Product ID: HY-10534. | |
| Voreloxin Hydrochloride | Voreloxin Hydrochloride is a first-in-class topoisomerase II inhibitor that intercalates DNA and induces site-selective DNA DSB, G2 arrest, and apoptosis. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SNS-595 Hydrochloride; Vosaroxin Hydrochloride; AG 7352 Hydrochloride. CAS No. 175519-16-1. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16518. | |
| Voriconazole | Voriconazole (UK-109496) is a second-generation, broad-spectrum triazole antifungal agent that inhibits fungal ergosterol biosynthesis. Voriconazole exerts its antifungal activity by inhibition of 14-α-lanosterol demethylation, which is mediated by fungal cytochrome P450 enzymes [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: UK-109496. CAS No. 137234-62-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-76200. | |
| (±)-Voriconazole | (±)-Voriconazole ((±)-UK-109496) is a relative configuration of Voriconazole (HY-76200). Voriconazole is an antifungal agent [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (±)-UK-109496. CAS No. 188416-29-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W337569. | |
| Voriconazole-d3 | Voriconazole-d 3 is the deuterium labeled Voriconazole. Voriconazole (UK-109496) is a second-generation, broad-spectrum triazole antifungal agent that inhibits fungal ergosterol biosynthesis. Voriconazole exerts its antifungal activity by inhibition of 14-α-lanosterol demethylation, which is mediated by fungal cytochrome P450 enzymes[1][2]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: UK-109496-d3. CAS No. 1217661-14-7. Pack Sizes: 500 μg; 1 mg. Product ID: HY-76200S. | |
| Voriconazole N-oxide | Voriconazole N-oxide (Voriconazole oxynitride) is a potent antifungal agent. Voriconazole N-oxide has phototoxicity and photocarcinogenicity. Voriconazole N-oxide does not sensitize keratinocytes to ultraviolet B (UVB) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Voriconazole oxynitride. CAS No. 618109-05-0. Pack Sizes: 1 mg. Product ID: HY-137989. | |
| Vorinostat | Vorinostat (SAHA) is a potent and orally active pan-inhibitor of HDAC1 , HDAC2 and HDAC3 (Class I) , HDAC6 and HDAC7 (Class II) and HDAC11 (Class IV) , with ID 50 values of 10 nM and 20 nM for HDAC1 and HDAC3, respectively. Vorinostat induces cell apoptosis [1] [4]. Vorinostat is also an effective inhibitor of human papillomaviruse (HPV)-18 DNA amplification [7]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SAHA; Suberoylanilide hydroxamic acid. CAS No. 149647-78-9. Pack Sizes: 10 mM * 1 mL; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-10221. | |
| Vornorexant | Vornorexant (ORN-0829; TS-142) is a potent dual OX1R and OX2R antagonist with IC50 values of 1.05 nM and 1.27 nM, respectively. Vornorexant exhibits potent sleep-promoting effects in vivo and can be used for insomnia research research. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ORN-0829; TS-142. CAS No. 1517965-94-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139559. | |
| Vorolanib | Vorolanib (CM082) is an orally active, potent multikinase VEGFR/PDGFR inhibitor. Vorolanib is a potent ATP-binding cassette (ABC) transporter inhibitor. Vorolanib is an angiogenesis inhibitor and has antitumor activity combined with ZD1839 (HY-50895) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CM082; X-82. CAS No. 1013920-15-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109019. | |
| Vortioxetine | Vortioxetine (Lu AA 21004) is an antagonist of 5-HT 3A and 5-HT 7 receptors ( K i : 3.7 nM, 19 nM) and an inhibitor of serotonin transporter ( SERT ) ( K i : 1.6 nM), as well as a 5-HT 1A agonist and a partial agonist of 5-HT 1B ( K i : 15 nM, 33 nM) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Lu AA 21004. CAS No. 508233-74-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-15414. | |
| Vortioxetine hydrobromide | Vortioxetine (Lu AA 21004) hydrobromide is an antagonist of 5-HT 3A and 5-HT 7 receptors (K i : 3.7 nM, 19 nM) and an inhibitor of 5-hydroxytryptamine transporter (SERT) (K i : 1.6 nM), as well as a 5-HT 1A agonist and a partial 5-HT 1B agonist (K i : 15 nM, 33 nM) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Lu AA21004 hydrobromide. CAS No. 960203-27-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-15414A. | |
| Voruciclib | Voruciclib is an orally active and selective CDK inhibitor with K i values of 0.626 nM-9.1 nM. Voruciclib potently blocks CDK9, the transcriptional regulator of MCL-1. Voruciclib represses expression of MCL-1 in multiple models of diffuse large B-cell lymphoma (DLBCL) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1000023-04-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-12422. | |
| Voruciclib hydrochloride | Voruciclib hydrochloride is an orally active and selective CDK inhibitor with K i values of 0.626 nM-9.1 nM. Voruciclib hydrochloride potently blocks CDK9, the transcriptional regulator of MCL-1. Voruciclib hydrochloride represses expression of MCL-1 in multiple models of diffuse large B-cell lymphoma (DLBCL) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1000023-05-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12422A. | |
| Voxelotor | Voxelotor (GBT 440) is a potent inhibitor of haemoglobin S (HbS) polymerization. Voxelotor has the potential for sickle cell disease (SCD) treatment [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GBT 440. CAS No. 1446321-46-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-18681. | |
| Voxilaprevir | Voxilaprevir (GS-9857) is a noncovalent, reversible inhibitor of HCV NS3/4A protease inhibitor (PI) with pangenotypic antiviral activity [1]. Voxilaprevir inhibits genotype 1b and 3a wild-type NS3 proteases with K i values of 0.038 nM and 0.066 nM, respectively [1]. Voxilaprevir is an orally active direct-acting antiviral agent ( DAA ) and can be used for HCV infection research [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GS-9857. CAS No. 1535212-07-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-19840. | |
| VPM peptide | VPM peptide is a dithiol protease-cleavable peptide cross-linker. VPM peptide can be incorporated into the backbone of the PEG-diacrylate (PEG-DA) macromer to form PEG hydrogel [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 1428885-83-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P3159. | |
| VSPPLTLGQLLS | VSPPLTLGQLLS is a small peptide FGFR3 inhibitor, peptide P3, inhibits FGFR3 phosphorylation. VSPPLTLGQLLS inhibits 9-cisRA-induced tracheal lymphangiogenesis and blocks lymphatic endothelial cell (LEC) proliferation, migration, and tubule formation [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 1206896-24-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P3695. | |
| VT-1598 | VT-1598 is an orally active and selective fungal inhibitor targeting CYP51. VT-1598 shows anti-fungal activity against Candida auris [1] [2]. VT-1598 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 2089320-99-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123777. | |
| VTP-27999 Hydrochloride | VTP-27999 Hcl is an alkyl amine Renin inhibitor; VTP-27999 is useful for Hypertension and End-Organ Diseases. Uses: Scientific research. Group: Signaling pathways. CAS No. 1264191-73-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-76652. | |
| VTP-27999 TFA | VTP-27999 TFA is an alkyl amine Renin inhibitor; VTP-27999 TFA is useful for Hypertension and End-Organ Diseases. Uses: Scientific research. Group: Signaling pathways. CAS No. 1013937-63-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-50769. | |
| VU0134992 hydrochloride | VU0134992 hydrochloride is the first subtype-preferring, orally active and selective Kir4.1 potassium channel pore blocker, with an IC 50 of 0.97 μM. VU0134992 hydrochloride is 9-fold selective for homomeric Kir4.1 over Kir4.1/5.1 concatemeric channels (IC 50 =9 μM) at -120 mV [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1052515-91-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-122560A. | |
| VU0360172 | VU0360172 is a potent and selective mGlu5 receptor positive allosteric modulator with an EC 50 value of 16 nM and a K i of 195 nM, respectively. VU0360172 stimulates polyphosphoinositide (PI) hydrolysis in vivo , which is abrogated in mGlu5 receptors gene deleted mice [1]. VU0360172 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1310012-12-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-120589. | |
| VU0364289 | VU0364289 is a highly selective mGlu5 positive allosteric modulator (PAM) (binds to the MPEP (HY-14609A) site), with an EC 50 of 1.6 μM. VU0364289 can reverse amphetamine-induced hyperlocomotion in a dose-dependent manner, which can be used for schizophrenia and other psychiatric research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1242443-29-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120727. | |
| VU0364770 | VU0364770 is a selective and potent positive allosteric modulator ( PAM ) of mGlu4. VU0346770 exhibits EC 50 s of 290 nM and 1.1 μM at rat mGlu4 and human mGlu4 receptor , respectively. VU0364770 exhibits antagonist activity at mGlu5 with a potency of 17.9 μM and PAM activity at mGlu6 with a potency of 6.8 μM. VU0364770 also possesses activity at MAO with K i values of 8.5 and 0.72 μM for human MAO-A and human MAO-B, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 61350-00-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100588. | |
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