MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| RBN012759 | RBN012759 is a potent, selective and orally active inhibitor of PARP14, with an IC50 of <3 nM. RBN012759 displays 300-fold selectivity over the monoPARPs and 1000-fold selectivity over the polyPARPs. RBN012759 decreases pro-tumor macrophage function and elicits inflammatory responses in tumor explants[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2360851-29-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136979. |  |
| RBN013209 | RBN013209 is an orally active small molecule inhibitor of CD38 with an IC50 of 0.01 to 0.1 ?M for human CD38. RBN013209 prevents the conversion of extracellular NAD+ to ADPR or cADPR in tumor cells and PBMCs. RBN013209 can be used in the study of tumor. In addition, RBN013209 enables CAR-T cells to maintain the naive state and central memory state, and decreases the expression of cell activation markers and exhaustion-related inhibitory receptors[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2597933-17-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144987. | |
| RBN-2397 | RBN-2397 is a potent, accross species and orally active NAD+ competitive inhibitor of PARP7 (IC50<3 nM). RBN-2397 selectively binds to PARP7 (Kd=0.001 ?M) and restores IFN signaling. RBN-2397 has the potential for the study of advanced or metastatic solid tumors[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2381037-82-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136174. | |
| RBN-3143 | RBN-3143 is a potent and NAD+-competitive catalytic PARP14 inhibitor with an IC50 value of 4 nM. RBN-3143 inhibits PARP14-mediated ADP-ribosylation and stabilizes PARP14 in cell lines. RBN-3143 can be used in research of lung inflammation[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2360853-16-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-150207. | |
| RBPJ Inhibitor-1 | RBPJ Inhibitor-1 (RIN1), the first RBPJ inhibitor, blocks the functional interaction of RBPJ with SHARP. RBPJ Inhibitor-1 (RIN1) inhibits NOTCH-dependent tumor cell proliferation[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RIN1. CAS No. 2682114-39-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137471. | |
| (R)-BPO-27 | (R)-BPO-27, the R enantiomer of BPO-27, is a potent, orally active and ATP-competitive CFTR inhibitor with an IC50 of 4 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1415390-47-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-19778. | |
| RC-3095 TFA | RC-3095 TFA is a selective bombesin/gastrin releasing peptide receptor (GRPR) antagonist[1]. RC-3095 TFA exerts protective effects by reducing gastric oxidative injury in the arthritic mice[2]. Uses: Scientific research. Group: Peptides. CAS No. 1217463-61-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0107A. | |
| (R)-Carvedilol | (R)-Carvedilol ((R)-BM 14190), the R-enantiomer of Carvedilol, is a non-selective ?/?-1 blocker. (R)-Carvedilol exerts protection against the vascular or cardiac toxicity of Doxorubicin (DOX)[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (R)-BM 14190. CAS No. 95093-99-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0006C. | |
| (R)-Citalopram oxalate | (R)-Citalopram oxalate is an anticonvulsant, antidepressant and muscle relaxant. (R)-Citalopram oxalate is at least 20-fold weaker than S-citalopram (Escitalopram; HY-14258) as inhibitor of the 5-HT transporter (SERT). (R)-Citalopram oxalate functionally antagonises S-citalopram in vivo and in vitro. (R)-Citalopram oxalate has an effect on the association of Escitalopram with the high affinity primary site, and on its dissociation from the 5-HT transporter, via an allosteric mechanism [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 219861-53-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-110289. | |
| RCM-1 | RCM-1 is a forkhead box M1 (FOXM1) inhibitor with an EC50 of 0.72 ?M in U2OS cells. RCM-1 blocks the nuclear localization and increased the proteasomal degradation of FOXM1. RCM-1 can be used for asthma and other chronic airway diseases research[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 339163-65-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19979. | |
| (R)-CPP | (R)-CPP is a highly potent NMDA receptor antagonist [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 126453-07-4. Pack Sizes: 1 mg. Product ID: HY-100814. | |
| (R)-CR8 | (R)-CR8, a second-generation analog of Roscovitine, is a potent CDK1/2/5/7/9 inhibitor. (R)-CR8 inhibits CDK1/cyclin B (IC50=0.09 ?M), CDK2/cyclin A (0.072 ?M), CDK2/cyclin E (0.041 ?M), CDK5/p25 (0.11 ?M), CDK7/cyclin H (1.1 ?M), CDK9/cyclin T (0.18 ?M) and CK1?/? (0.4 ?M). (R)-CR8 induces apoptosis and has neuroprotective effect[1][2]. (R)-CR8 acts as a molecular glue degrader that depletes cyclin K[3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CR8, (R)-Isomer. CAS No. 294646-77-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18340. (R)?-?CR8 | |
| (R)-Donepezil | (R)-Donepezil is a R-enantiomer of Donepezil (HY-14566). Donepezil is a specific and potent AChE inhibitor [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (R)-E2020 free base. CAS No. 142698-19-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136838. | |
| Reactive Blue 19 | Reactive Blue 19 is an anthraquinone dye used in the textile industry as a starting material to produce polymeric dye [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 2580-78-1. Pack Sizes: 100 mg; 500 mg; 1 g. Product ID: HY-D0331. | |
| Reactive Blue 4 | Reactive Blue 4 is an anthraquinone dye, as a single colorimetric chemosensor for sequential determination of multiple analytes with different optical responses in aqueous media. Reactive Blue 4 is phytotoxic, cytotoxic and genotoxic. Reactive Blue 4 [1] [2]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 13324-20-4. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-125815. | |
| Rebamipide | Rebamipide (OPC12759) is an orally active gastroprotective agent that enhances the production of endogenous PGs (especially intragastric PGE2 ) by inducing COX-2 expression, thereby protecting the gastric mucosa from injury. Rebamipide exerts anti-proliferative activity against gastric cancer cells. Rebamipide can be used in studies of mucosal protection, gastroduodenal ulcer, gastritis and gastric cancer [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: OPC12759; Proamipide. CAS No. 90098-04-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0360. | |
| Rebastinib | Rebastinib (DCC-2036) is an orally active, non-ATP-competitive Bcr-Abl inhibitor for Abl1WT and Abl1T315I with IC50s of 0.8 nM and 4 nM, respectively. Rebastinib also inhibits SRC, KDR, FLT3, and Tie-2, and has low activity to seen towards c-Kit. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DCC-2036. CAS No. 1020172-07-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-13024. | |
| Rebaudioside A | Rebaudioside A is a steviol glycoside with high sweetness potency and is a potent α-glucosidase inhibitor with an IC 50 value of 35.01 ug/mL. Rebaudioside A directly stimulates insulin secretion from pancreatic beta cells via inhibition of ATP-sensitive K + -channels [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. CAS No. 58543-16-1. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-N0466. | |
| Rebaudioside C | Rebaudioside C (Dulcoside B) is a natural sweetener that can be used in controlled diets for diabetic patients. Uses: Scientific research. Group: Natural products. Alternative Names: Dulcoside B. CAS No. 63550-99-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0467. | |
| Rebaudioside D | Rebaudioside D is a glycoside found in the leaves of Stevia rebaudiana and acts as a sweetener [1]. Uses: Scientific research. Group: Natural products. CAS No. 63279-13-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N0468. | |
| Rebaudioside M | Rebaudioside M, a glycoside of the ent-kaurene diterpenoid aglycone, is a non-calorie sweetener isolated from Stevia rebaudiana. Rebaudioside M has antidiabetics, antihypertension, anti-inflammatory, antioxidant, anticaries and anticancer benefits. Rebaudioside M is more than 350 times sweeter than sucrose. Rebaudioside M can be used in food and beverage [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Natural products. CAS No. 1220616-44-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N6833. | |
| Reboxetine mesylate | Reboxetine mesylate (FCE20124 mesylate) is a potent, selective, and specific noradrenaline reuptake inhibitor (NARI) for the research of depression. Reboxetine mesylate inhibits the uptake of norepinephrine, with a K i of 8 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FCE20124 mesylate; PNU155950E mesylate. CAS No. 98769-84-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-14560C. | |
| Recainam | Recainam (Wy-42362) is an orally active anti-arrhythmic agent with Class I electrophysiological properties. Recainam suppresses complex ventricular arrhythmias. Racainam exhibits a good pharmacokinetic character in Sprague Dawley rats [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Wy-42362. CAS No. 74738-24-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-105454. | |
| Recaticimab | Recaticimab (SHR-1209) is an orally active humanized monoclonal antibody targeting PCSK9. Recaticimab binds PCSK9 with high affinity, increases the level of low density lipoprotein receptor on the surface of liver cells, and decreases the level of low density lipoprotein cholesterol in plasma. Recaticimab can be used in the study of hypercholesterolemia and hyperlipidemia [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: SHR-1209. CAS No. 2361290-85-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99822. | |
| Recifercept | Recifercept (TA-46) is a soluble, recombinant fibroblast growth factor receptor 3 (FGFR3) molecule. Recifercept can be used as a decoy/ligand trap to decrease the amount of fibroblast growth factors that can bind to mutant FGFR3 receptors. Recifercept can be used for the research of achondroplasia [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: TA-46; sFGFR3. CAS No. 2226238-09-9. Pack Sizes: 500 μg; 1 mg; 5 mg; 10 mg. Product ID: HY-P99823. | |
| Recilisib | Recilisib (ON 01210) is a radioprotectant, which can activate AKT, PI3K activities in cells[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ON 01210. CAS No. 334969-03-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101625. | |
| Recombinant DNase I (RNase-free) | Recombinant DNase I (RNase-free) is a recombinant deoxyribonuclease that degrades DNA. Recombinant DNase I is essential for limiting inflammatory responses and maintaining homeostasis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 9003-98-9. Pack Sizes: 200 U; 500 U; 1 KU. Product ID: HY-108882A. | |
| Recombinant enterokinase | Recombinant enterokinase (rEK) is a serine protease and functions as the physiological activator of trypsinogen. Recombinant enterokinase plays a role of turning trypsinogen to its active form trypsin [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: rEK. CAS No. 9014-74-8. Pack Sizes: 100 U. Product ID: HY-E70202. | |
| Recombinant Human Serum Albumin(rHSA) | Recombinant Human Serum Albumin (rHSA) is an active compound and possesses an identical conformation to plasma derived HSA. Recombinant Human Serum Albumin (rHSA) has no difference between rHSA and plasma derived HSA. The main physiological function of Recombinant Human Serum Albumin (rHSA) is to regulate plasma pH and maintain plasma osmotic pressure[1]. Uses: Scientific research. Group: Biochemical assay reagents. Pack Sizes: 500 mg; 1 g; 5 g. Product ID: HY-150097. | |
| Recombinant Kex2 protease | Recombinant Kex2 protease is a membrane-bound, Ca 2+ -dependent serine protease. Recombinant Kex2 protease specifically recognize and cleave the carboxyl-terminal peptide bonds of dibasic amino acids [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 99676-46-7. Pack Sizes: 1 mg. Product ID: HY-E70200. | |
| Redafamdastat | Redafamdastat (PF-04457845) is a highly efficacious and selective FAAH inhibitor with IC50 values is 7.2±0.63 nM and 7.4±0.62 nM for hFAAH and rFAAH, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PF-04457845. CAS No. 1020315-31-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14376. | |
| Redaporfin | Redaporfin (LUZ11) acts as a potent photosensitizer. Redaporfin causes direct antineoplastic effects as well as indirect immune-dependent destruction of malignant lesions [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LUZ11; F2BMet. CAS No. 1224104-08-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-17644. | |
| Refametinib | Refametinib (BAY 869766; RDEA119) is an orally available, potent, non-ATP-competitive, selective, allosteric MEK1/MEK2 inhibitor with IC50s of 19 nM and 47 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 869766; RDEA119. CAS No. 923032-37-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14691. | |
| Regadenoson | Regadenoson (CVT-3146) is a selective A2A adenosine receptor agonist and vasodilator that increases coronary blood flow, can be used in study of myocardial perfusion imaging. Regadenoson also increases the permeability of the blood-brain barrier (BBB) in rodents, can be used to study increased delivery of agents to the human CNS [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CVT-3146. CAS No. 313348-27-5. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0168. | |
| Regaloside B | Regaloside B is a phenylpropanoid isolated from Lilium longiflorum. Regaloside B can inhibit the expression of iNOS and COX-2. Regaloside B has anti-inflammatory activity[1][2]. Uses: Scientific research. Group: Natural products. CAS No. 114420-67-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N7688. | |
| Regdanvimab | Regdanvimab (CT-P59) is a human monoclonal antibody that targets the receptor-binding domain of SARS-CoV-2 spike protein, blocking interaction with ACE2 for viral entry. Regdanvimab can be used for the research of COVID-19 [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: CT-P59. CAS No. 2444308-95-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99346. | |
| Regorafenib | Regorafenib (BAY 73-4506) is an orally active and potent multi-targeted receptor tyrosine kinase inhibitor, with IC 50 values of 13/4.2/46, 22, 7, 1.5 and 2.5 nM for VEGFR1/2/3 , PDGFRβ , Kit , RET and Raf-1 , respectively. Regorafenib shows very robust antitumor and antiangiogenic activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 73-4506. CAS No. 755037-03-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-10331. | |
| Regorafenib Hydrochloride | Regorafenib Hydrochloride (BAY 73-4506 hydrochloride) is a multi-target inhibitor for VEGFR1/2/3 , PDGFRβ , Kit , RET and Raf-1 with IC 50 s of 13/4.2/46, 22, 7, 1.5 and 2.5 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 73-4506 hydrochloride. CAS No. 835621-07-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13308. | |
| Regorafenib monohydrate | Regorafenib (BAY 73-4506) monohydrate is an orally active and potent multi-targeted receptor tyrosine kinase inhibitor, with IC 50 values of 13/4.2/46, 22, 7, 1.5 and 2.5 nM for VEGFR1/2/3 , PDGFRβ , Kit , RET and Raf-1 , respectively. Regorafenib monohydrate shows very robust antitumor and antiangiogenic activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 73-4506 monohydrate. CAS No. 1019206-88-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10331A. | |
| Rehmannioside D | Rehmannioside D is a carotenoid glycoside. Uses: Scientific research. Group: Natural products. CAS No. 81720-08-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0912. | |
| Relacatib | Relacatib (SB-462795) is a novel, potent, and orally active inhibitor of human cathepsins K, L, and V with Ki values of 41 pM, 68 pM, and 53 pM, respectively. Relacatib inhibits endogenous cathepsin K in situ in human osteoclasts and human osteoclast-mediated bone resorption with IC50 values of 45 nM and 70 nM, respectively. Relacatib inhibits bone resorption in vitro in human tissue as well as in cynomolgus monkeys in vivo[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SB-462795. CAS No. 362505-84-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-10294. | |
| Relacorilant | Relacorilant is a potent, selective and orally bioavailable glucocorticoid receptor antagonist, with a K i of 7.2 nM in HepG2 TAT assay, and also shows K i s of 12, 81.2, 210 nM for rat, human and monkey glucocorticoid receptor in cell-based assay, respectively. Relacorilant has the potential for Cushings syndrome treatment. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CORT 125134. CAS No. 1496510-51-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109042. | |
| Relamorelin TFA | Relamorelin (RM-131) TFA, a pentapeptide ghrelin analog, is a selective ghrelin/growth hormone secretagogue receptor (GHSR) agonist with a K i of 0.42 nM for GHS-1a receptor. Relamorelin TFA is centrally penetrant. Relamorelin TFA increases growth hormone levels and accelerates gastric emptying. Relamorelin TFA has the potential for cachexia, gastroparesis, and gastric/intestinal dysmobility disorders research [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Peptides. Alternative Names: RM-131 TFA; BIM-28131 TFA. CAS No. 2863659-22-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19884B. | |
| Relatlimab | Relatlimab (BMS-986016) is a human monoclonal antibody anti-LAG-3 antibody generated by immunization of transgenic mice bearing human immunoglobulin miniloci with recombinant LAG-3 protein. Relatlimab blocks LAG-3/MHC II interaction with an IC 50 value of 0.67 nM and LAG-3/FGL1 interaction with an IC 50 value of 0.019 nM. Relatlimab can be used in research of cancer [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BMS-986016. CAS No. 1673516-98-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99156. | |
| (rel)-β-Tocopherol | (rel)-β-Tocopherol is a relative configuration of β -Tocopherol.(±)-β -Tocopherol is a lipid-soluble form of vitamin E with antioxidant activity. β-Tocopherol can inhibit tyrosinase activity and melanin synthesis. β-Tocopherol also can prevent the inhibition of cell growth and of PKC activity caused by d-alpha-tocopherol [1]. Uses: Scientific research. Group: Natural products. CAS No. 148-03-8. Pack Sizes: 1 mg (119.99 mM * 20 μL in Hexane); 5 mg (119.99 mM * 100 μL in Hexane); 10 mg (119.99 mM * 200 μL in Hexane). Product ID: HY-113068. | |
| Reldesemtiv | Reldesemtiv (CK-2127107) is a selective, orally active and next-generation fast skeletal muscle troponin activator (FSTA). Reldesemtiv selectively activates fast skeletal myofibrils with an EC 50 of 3.4 μM. Reldesemtiv increases exercise performance in a heart failure model [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CK-2127107. CAS No. 1345410-31-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109121. | |
| Relebactam | Relebactam is a diazabicyclooctane inhibitor with activity against a wide spectrum of β-lactamases , including class A (extended-spectrum β-lactamases and KPC) and class C (AmpC) enzymes. Relebactam shows antibacterial activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-7655. CAS No. 1174018-99-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16752. | |
| (rel)-ML-SI3 | (rel)-ML-SI3 is one of the active ingredients of ML-SI3 (HY-139426) (another component is (cis)-ML-SI3) that targets three isoforms of TRPML. (rel)-ML-SI3 is an inhibitor of TRPML1 and TRPML3 (IC50=3.1 ?M/28.5 ?M), and a potent activator of TRPML2 (EC50=3.3 ?M)[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: trans-ML-SI3. CAS No. 2108567-79-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139426A. | |
| Relugolix | Relugolix (TAK-385) is a potent, orally active, nonpeptidic gonadotropin-releasing hormone (GnRH) antagonist. Relugolix possesses high affinity and potent antagonistic activity for human receptor (binding IC 50 =0.33 nM) and monkey receptor ( IC 50 =0.32 nM) compared with TAK-013 (HY-100209) [1]. Relugolix is used for the study of sex-hormone-dependent diseases, such as including endometriosis, uterine fibroids and prostate cancer et al [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TAK-385. CAS No. 737789-87-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16474. | |
| Relutrigine | Relutrigine (PRAX-562) is an orally active inhibitor of persistent sodium channel. Relutrigine potently and preferentially inhibits persistent INa induced by ATX-II (Nav 1.5 activator) or the SCN8A mutation N1768D with IC50 values of 141 nM and 75 nM, respectively. Relutrigine exhibits potent use-dependent block and reduces neuronal intrinsic excitability. Relutrigine has effective anticonvulsant activity[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PRAX-562. CAS No. 2392951-29-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-148792. | |
| Remacemide | Remacemide (FPL 12924) is an orally active, non-competitive, low-affinity NMDA receptor antagonist. Remacemide shows neuroprotection activity in animal models of hypoxia and ischemic stroke. Remacemide is also an anticonvulsant, and can be used in Parkinson's disease and Huntington's disease research [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FPL 12924; PR 934-423; FPL 13592. CAS No. 128298-28-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-160604. | |
| Remdesivir | Remdesivir (GS-5734), a nucleoside analogue with effective antiviral activity, has EC 50 s of 3.3 μM, 4.7 μM, 32 μM, 3.7 μM and 9.2 μM for SARS-CoV-2 and its variants alpha, beta, gamma and delta, respectively. Remdesivir is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GS-5734. CAS No. 1809249-37-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-104077. | |
| Remdesivir (Standard) | Remdesivir (Standard) is the analytical standard of Remdesivir. This product is intended for research and analytical applications. Remdesivir (GS-5734), a nucleoside analogue with effective antiviral activity, has EC 50 s of 3.3 μM, 4.7 μM, 32 μM, 3.7 μM and 9.2 μM for SARS-CoV-2 and its variants alpha, beta, gamma and delta, respectively. Remdesivir is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1809249-37-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-104077R. | |
| Remibrutinib | Remibrutinib, is a potent and orally active bruton tyrosine kinase (BTK) inhibitor with an IC 50 value of 1 nM. Remibrutinib inhibits BTK activity with an IC 50 value of 0.023 μM in blood [1]. Remibrutinib has the potential for Chronic urticaria (CU) treatment [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LOU064. CAS No. 1787294-07-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-128757. | |
| Remodelin | Remodelin is an orally active and selective inhibitor of acetyltransferase NAT10. Remodelin inhibits NAT10 activitity and slows DNA replication and suppresses growth of prostate cancer cells. Remodelin inhibits the growth of prostate cancer and hepatocellular carcinoma in xenograft model. Remodelin enhances the healthspan in hutchinson-gilford progeria syndrome (HGPS) mouse model[1][2][3][4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 949912-58-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16706. | |
| Remodelin hydrobromide | Remodelin hydrobromide is an orally active and selective inhibitor of acetyltransferase NAT10. Remodelin hydrobromide inhibits NAT10 activitity and slows DNA replication and suppresses growth of prostate cancer cells. Remodelin hydrobromide inhibits the growth of prostate cancer and hepatocellular carcinoma in xenograft model. Remodelin hydrobromide enhances the healthspan in hutchinson-gilford progeria syndrome (HGPS) mouse model[1][2][3][4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1622921-15-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-16706A. | |
| Remogliflozin | Remogliflozin is a potent and selective inhibitor of SGLT2 (sodium-glucose cotransporter 2) with K i s of 12.4 and 26 nM for human and rat SGLT2, respectively. Remogliflozin is the active form of Remogliflozin etabonate(HY-14945) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Remogliflozin A. CAS No. 329045-45-6. Pack Sizes: 5 mg. Product ID: HY-13414. | |
| Remogliflozin etabonate | Remogliflozin etabonate (GSK189075) is an orally active, selective and low-affinity sodium glucose cotransporter (SGLT2) inhibitor with K i values of 1.95 μM, 2.14 μM, 43.1 μM, 8.57 μM for hSGLT2, rSGLT2, hSGLT1, rSGLT1, respectively. Remogliflozin etabonate is a proagent based on benzylpyrazole glucoside and is metabolized to its active form, Remogliflozin, in the body. Remogliflozin etabonate exhibits antidiabetic efficacy in rodent models [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GSK189075. CAS No. 442201-24-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14945. | |
| Remternetug | Remternetug is a human immunoglobulin G1-kappa, anti-APP (amyloid beta A4 precursor protein) Aβ42 N3pGlu peptide monoclonal antibody. Remternetug recognizes a pyroglutamated form of A&beta. Remternetug results in rapid and robust amyloid plaque reduction. Remternetug can be used for Alzheimer's disease research [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: LY3372993. CAS No. 2571940-41-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990078. | |
| Rencofilstat | Rencofilstat (CRV431) is a pan-cyclophilin inhibitor with IC 50 values of 2.5 nM, 3.1 nM, 2.8 nM, 7.3 nM for Cyp A, CypB, Cyp D and Cyp G, respectively. Rencofilstat reduces fibrosis and tumor growth in models of chronic liver disease [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CRV431. CAS No. 1383420-08-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-135644. | |
| Rennin | Rennin, also known as Chymosin, is a pepsin-related proteolytic enzyme synthesized by cells in the stomach of certain animals that efficiently converts liquid milk into a semi-solid, allowing it to remain in the stomach for longer. The natural substrate of Rennin is K-casein, which is specifically cleaved at the peptide bond between amino acid residues 105 and 106, phenylalanine and methionine, and is widely used in cheese production [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EC 3.4.23.4. CAS No. 9001-98-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P2810. | |
| Renzapride | Renzapride (BRL 24924), a substituted benzamide, is a full 5-HT 4 receptor agonist with a K i value of 115 nM. Renzapride (BRL 24924) is also a 5HT2b and 5HT3 receptor antagonist [1]. Renzapride could be used for constipation predominant irritable bowel syndrome (C-IBS) study [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BRL 24924. CAS No. 112727-80-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14147. | |
| Repaglinide | Repaglinide is an insulin secretagogue for the treatment of type-2 diabetes mellitus [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AG-EE 623ZW. CAS No. 135062-02-1. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-15209. | |
| Repaglinide (Standard) | Repaglinide (Standard) is the analytical standard of Repaglinide. This product is intended for research and analytical applications. Repaglinide is an insulin secretagogue for the treatment of type-2 diabetes mellitus [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AG-EE 623ZW (Standard). CAS No. 135062-02-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15209R. | |
| Reparixin | Reparixin is a non-competitive allosteric inhibitor of the chemokine receptors CXCR1 and CXCR2 activation with IC 50 s of 1 and 100 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Repertaxin; DF 1681Y. CAS No. 266359-83-5. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15251. | |
| Reparixin L-lysine salt | Reparixin L-lysine salt is an allosteric inhibitor of chemokine receptor 1/2 (CXCR1/2) activation. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Repertaxin L-lysine salt. CAS No. 266359-93-7. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-15252. | |
| Repinotan hydrochloride | Repinotan hydrochloride (BAY x 3702) is a potent, selective, brain-penetrant and orally active 5-HT1A receptor agonist, with K i values of 0.19 nM (calf hippocampus), 0.25 nM (rat and human cortex), and 0.59 nM (rat hippocampus Repinotan hydrochloride has a weak affinity for other related receptors. Repinotan hydrochloride has pronounced neuroprotective effects [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY x 3702. CAS No. 144980-77-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-12959A. | |
| Repirinast | Repirinast (MY-5116) is an orally active anti-allergic agent. Repirinast inhibits histamine release. Repirinast can be used in the research of bronchial asthma [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MY-5116. CAS No. 73080-51-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109544. | |
| Repotrectinib | Repotrectinib (TPX-0005) is a potent ROS1 ( IC 50 =0.07 nM) and TRK ( IC 50 =0.83/0.05/0.1 nM for TRKA/B/C) inhibitor. Repotrectinib potently inhibits WT ALK ( IC 50 =1.01 nM). Repotrectinib has anti-cancer activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TPX-0005. CAS No. 1802220-02-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-103022. | |
| Reproterol | Reproterol is a dual acting β2-adrenoceptor agonist and PDE inhibitor. The theophylline constituent of Reproterol inhibits phosphodiesterase activity induced by adenylyl cyclase. Reproterol has the potential for asthma research [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 54063-54-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-135490. | |
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