MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| RS102895 | RS102895 is a potent CCR2 antagonist, with an IC 50 of 360 nM, and shows no effect on CCR1. Uses: Scientific research. Group: Signaling pathways. CAS No. 300815-41-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-18611A. |  |
| RS102895 hydrochloride | RS102895 hydrochloride is a potent CCR2 antagonist, with an IC 50 of 360 nM, and shows no effect on CCR1. Uses: Scientific research. Group: Signaling pathways. CAS No. 1173022-16-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-18611. | |
| RS-127445 | RS-127445 is a selective, high affinity, orally bioavailable 5-HT 2B receptor antagonist with a pK i of 9.5. RS-127445 shows 1000 fold selectivity for this receptor as compared to numerous other receptor and ion channel binding sites [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 199864-87-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15419A. | |
| RS-127445 hydrochloride | RS-127445 hydrochloride is a selective, high affinity, orally bioavailable 5-HT 2B receptor antagonist with a pK i of 9.5. RS-127445 hydrochloride shows 1000 fold selectivity for this receptor as compared to numerous other receptor and ion channel binding sites [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 199864-86-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15419. | |
| RS17 | RS17 is an anti-tumor peptide designed to bind specifically to the CD47 molecule and block the interaction between CD47 and its ligand, SIRPα, on the surface membrane of macrophages. The main regulatory mechanism of RS17 is to prevent CD47 from transmitting selective phagocytosis signals to SIRPα by binding to CD47 , so that macrophages do not recognize tumor cells as their own tissue, but phagocytose them as foreign substances, thereby inhibiting immune escape of tumor cells. RS17 can be used to study the mechanism of anti-tumor response and immune escape [1]. Uses: Scientific research. Group: Peptides. CAS No. 2415545-08-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P10420. | |
| RS-246204 | RS-246204 is a R-spondin-1 substitute compound that is able initiate small intestinal organoids without the use of the R-spondin-1 protein. Uses: Scientific research. Group: Signaling pathways. CAS No. 878451-87-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112484. | |
| (R,S)-4-Hydroxy Cyclophosphamide-d4 Preparation Kit | (R,S)-4-Hydroxy Cyclophosphamide-d 4 Preparation Kit is the deuterium labeled (R,S)-4-Hydroxy Cyclophosphamide Preparation Kit. (R,S)-4-Hydroxy Cyclophosphamide is an isomer of 4-Hydroxycyclophosphamide, the active metabolite of the cytotoxic alkylating agent Cyclophosphamide (HY-17420) [1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 1329838-09-6. Pack Sizes: 2.5 mg. Product ID: HY-132451S. | |
| RS 504393 | RS 504393 is a selective CCR2 chemokine receptor antagonist ( IC 50 values are 89 nM and > 100 μM for inhibition of human recombinant CCR2 and CCR1 receptors respectively). Uses: Scientific research. Group: Signaling pathways. CAS No. 300816-15-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15418. | |
| RS 67333 hydrochloride | RS 67333 hydrochloride is a potent and selective 5-HT4 receptor (5-HT4R) partial agonist with a pK i of 8.7 in guinea-pig striatum. RS 67333 hydrochloride exhibits lower affinities at several other receptors including 5-HT1A, 5-HT1D, 5-HT2A, 5-HT2C, dopamine D1, D2 and muscarinic M1-M3 receptors. RS 67333 hydrochloride has neuroprotective effects, and can be used for Alzheimer's disease research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 168986-60-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101341. | |
| (R,S)-Anatabine | (R,S)-Anatabine is a a minor tobacco alkaloid found in the Solanaceae family of plants that can be used as a specific marker for the detection of tobacco use[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2743-90-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126047A. | |
| RSL3 | RSL3 ((1S,3R)-RSL3) is an inhibitor of glutathione peroxidase 4 (GPX4) (ferroptosis activator), reduces the expression of GPX4 protein, and induces ferroptotic death of head and neck cancer cell. RSL3 increases the expression of p62 and Nrf2 and inactivates Keap1 in HN3-rslR cells[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (1S,3R)-RSL3. CAS No. 1219810-16-8. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100218A. | |
| RSM-932A | RSM-932A (TCD-717) is a specific ChoK? inhibitor with IC50s of 1 and 33 ?M for human recombinant ChoK? and ChoK? enzymes, respectively. RSM-932A acts as the first in humans compound targeting ChoK?. RSM-932A is potent in vitro anti-proliferative and in vivo anti-tumoral activity against human xenografts in mice, showing high efficacy with low toxicity profiles[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TCD-717. CAS No. 850807-63-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101144. | |
| (R)-Sulforaphane | (R)-Sulforaphane (L-Sulforaphane) is a orally active, potent inducer of the Keap1/Nrf2/ARE pathway, exhibiting antioxidant and anticancer activities. (R)-Sulforaphane primarily functions by upregulating phase II detoxifying enzymes in cells, aiding in the removal of carcinogens and combating oxidative stress. (R)-Sulforaphane is capable of modulating gene expression, influencing various signaling pathways, including Nrf2, NF-?B, and AP-1. (R)-Sulforaphane can be used in studies of tumor biology, antioxidant defense mechanisms, as well as inflammation and immune responses[1][2][3][4][5][6][7]. Uses: Scientific research. Group: Natural products. Alternative Names: L-Sulforaphane. CAS No. 142825-10-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-13755A. | |
| RSV-IN-1 | RSV-IN-1 is a human respiratory syncytical virus (hRSV) inhibitor, with an IC 50 of 0.11 μM. Uses: Scientific research. Group: Signaling pathways. CAS No. 861139-16-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-112673. | |
| (R)-(+)-tert-Butylsulfinamide | (R)-(+)-tert-Butylsulfinamide is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: (R)-2-Methylpropane-2-sulfinamide. CAS No. 196929-78-9. Pack Sizes: 10 mM * 1 mL; 25 g. Product ID: HY-40228. | |
| (R)-Tetrahydrofuran-2-carboxylic acid | (R)-(+)-2-Tetrahydrofuroic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: (R)-(+)-Tetrahydrofuran-2-carboxylic acid. CAS No. 87392-05-0. Pack Sizes: 5 g; 25 g. Product ID: HY-W005223. | |
| (R)-Thalidomide | (R)-Thalidomide ((R)-(+)-Thalidomide) is the R-enantiomer of Thalidomide. (R)-Thalidomide has psychomotor stabilizing properties [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (R)-(+)-Thalidomide. CAS No. 2614-6-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-14658B. | |
| RTI-7470-44 | RTI-7470-44 is a potent, selective and blood-brain barrier (BBB) penetrant human trace amine-associated receptor subtype 1 (hTAAR1) antagonist with an IC50 value of 8.4 nM and a Ki value of 0.3 nM. RTI-7470-44 has moderate metabolic stability, and a favorable preliminary off-target profile. RTI-7470-44 can increase the spontaneous firing rate of mouse ventral tegmental area (VTA) dopaminergic neurons. RTI-7470-44 can be used for researching schizophrenia, agent addiction, and Parkinsons disease (PD)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 825658-63-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-147319. | |
| rTRD01 | rTRD01 is a TDP-43 ligand that binds to TDP-43s RRM1 and RRM2 domains (Kd=89 uM for TDP-43102-269). rTRD01 partially disrupts TDP-43s interaction with the hexanucleotide RNA repeat of the disease-linked c9orf72 gene. rTRD01 can be used for the research of neurodegenerative diseases[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1332175-56-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-153898. | |
| (R)-Trolox | (R)-Trolox is a vitamin E analogue and a competitive tyrosinase inhibitor with a Ki value of 0.83 mM and a ID50 value of 1.88 mM[1]. The (R)-Trolox has stronger tyrosinase affinity than the (S) enantiomer (Ki value of 0.61 mM)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 53101-49-8. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-101445A. | |
| RU 24969 | RU 24969 is a preferential 5-HT1B agonist, with a Ki of 0.38 nM, but also displays appreciable affinity for the 5-HT1A receptor (Ki=2.5 nM), and has low affinity for other receptor sites in the brain. RU 24969 could decrease fluid consumption and increase forward locomotion[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 66611-26-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16688. | |
| RU.521 | RU.521 (RU320521) is a potent and selective cyclic GMP-AMP synthase (cGAS) inhibitor and inhibits cGAS-mediated interferon upregulation. RU.521 suppresses dsDNA-activated reporter activity with an IC 50 of 0.7 μM. RU.521 reduces constitutive expression of interferon in macrophages from a mouse model of Aicardi-Goutières syndrome (AGS) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RU320521. CAS No. 2262452-06-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114180. | |
| RU 58841 | RU 58841 (PSK-3841) is a specific androgen receptor antagonist or anti-androgen. RU 58841 has a dramatic effect on hair regrowth [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PSK-3841; HMR-3841. CAS No. 154992-24-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10561. | |
| Ru(acac)3 | Ru(acac)3 (Tris(acetylacetonato)ruthenium (III)) is a biochemical reagent that can be used as a biological material or organic compound for life science related research [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Tris(acetylacetonato)ruthenium (III). CAS No. 14284-93-6. Pack Sizes: 1 g. Product ID: HY-W020958. | |
| Rubiadin | Rubiadin is a dihydroxy anthraquinone isolated from Rubia cordifolia. Rubiadin has a potent antixidant activity [1]. Uses: Scientific research. Group: Natural products. CAS No. 117-02-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N0444. | |
| Rubiadin-1-methyl ether | Rubiadin-1-methyl ether is a natural anthraquinone isolated from Morinda officinalis How, and inhibits osteoclastic bone resorption via inhibition on the phosphorylation of NF-κB p65 and the degradation of IκBα as well as decrease in the nuclear translocation of p65 [1]. Uses: Scientific research. Group: Natural products. CAS No. 7460-43-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N1956. | |
| Rubitecan | Rubitecan (RFS 2000), a Camptothecin derivative, is an orally active topoisomerase I inhibitor with broad antitumor activity, and induces protein-linked DNA single-strand breaks, thereby blocking DNA and RNA synthesis in dividing cells [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: RFS 2000; 9-Nitrocamptothecin. CAS No. 91421-42-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13744. | |
| Ruboxistaurin | Ruboxistaurin (LY333531) is an orally active, selective PKC beta inhibitor ( K i =2 nM). Ruboxistaurin exhibits ATP dependent competitive inhibition of PKC beta I with an IC 50 of 4.7 nM. Ruboxistaurin inhibits PKC beta II with an IC 50 of 5.9 nM [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY333531. CAS No. 169939-94-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10195. | |
| Ruboxistaurin hydrochloride | Ruboxistaurin (LY333531) hydrochloride is an orally active, selective PKC beta inhibitor ( K i =2 nM). Ruboxistaurin hydrochloride exhibits ATP dependent competitive inhibition of PKC beta I with an IC 50 of 4.7 nM. Ruboxistaurin hydrochloride inhibits PKC beta II with an IC 50 of 5.9 nM [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY333531 hydrochloride. CAS No. 169939-93-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10195B. | |
| Ruboxistaurin mesylate | Ruboxistaurin (LY333531) mesylate is an orally active, selective and ATP competitive PKCβ inhibitor with IC 50 values of 4.7 and 5.9 nM for PKCβI and PKCβII, respectively. Ruboxistaurin mesylate can be used for the research of eye disorders, heart failure and diabetes [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY333531 mesylate. CAS No. 192050-59-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-10195A. | |
| Rucaparib | Rucaparib (AG014699) is an orally active, potent inhibitor of PARP proteins (PARP-1, PARP-2 and PARP-3) with a K i of 1.4 nM for PARP1. Rucaparib is a modest hexose-6-phosphate dehydrogenase (H6PD) inhibitor. Rucaparib has the potential for castration-resistant prostate cancer (CRPC) research [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AG014699; PF-01367338. CAS No. 283173-50-2. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10617A. | |
| Rucaparib monocamsylate | Rucaparib (AG014699) monocamsylate is an orally active, potent inhibitor of PARP proteins (PARP-1, PARP-2 and PARP-3) with a K i of 1.4 nM for PARP1. Rucaparib monocamsylate is a modest hexose-6-phosphate dehydrogenase (H6PD) inhibitor. Rucaparib monocamsylate has the potential for castration-resistant prostate cancer (CRPC) research [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AG014699 monocamsylate; PF-01367338 monocamsylate. CAS No. 1859053-21-6. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-102003. | |
| Rucaparib phosphate | Rucaparib (AG014699) phosphate is an orally active, potent inhibitor of PARP proteins (PARP-1, PARP-2 and PARP-3) with a K i of 1.4 nM for PARP1. Rucaparib phosphate is a modest hexose-6-phosphate dehydrogenase (H6PD) inhibitor. Rucaparib phosphate has the potential for castration-resistant prostate cancer (CRPC) research [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AG-014699 phosphate; PF-01367338 phosphate. CAS No. 459868-92-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10617. | |
| Rufinamide | Rufinamide (E 2080; CGP 33101; RUF 331) is a novel anticonvulsant compound that can inhibit Na + current activation, and be used in the research of Lennox-Gastaut syndrome. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CGP 33101; E 2080; RUF 331. CAS No. 106308-44-5. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0042. | |
| Rufloxacin hydrochloride | Rufloxacin hydrochloride (MF-934 hydrochloride) is a fluoroquinolone antibacterial, inhibits B-cell differentiation in human mononuclear cells, inhibits Topo. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MF-934 hydrochloride. CAS No. 106017-08-7. Pack Sizes: 50 mg; 100 mg. Product ID: HY-B0902A. | |
| Rugocrixan | AZD8797 (KAND567) is an allosteric non-competitive and orally active antagonist of the human CX3CR1 receptor; antagonizes CX3CR1 and CXCR2 with Kis of 3.9 and 2800 nM, respectively[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AZD8797; KAND567. CAS No. 911715-90-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13848. | |
| Runcaciguat | Runcaciguat is an orally active stimulator of soluble guanylate cyclase , and is used in the research of cardiovascular and renal diseases combined with selective partial adenosine A1 receptor agonists [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 1101042. CAS No. 1402936-61-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109136. | |
| Runimotamab | Runimotamab is an IgG1-κ humanized chimeric antibody targeting CD3E and HER2 [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2361325-98-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99896. | |
| Rupatadine | Rupatadine (UR-12592) is a potent, orally active and long-lasting dual PAF/H1 antagonist, with K i s of 0.55 μM and 0.1 μM, respectively. Rupatadine can be used for the research of allergic rhinitis and urticaria [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: UR-12592. CAS No. 158876-82-5. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-13511. | |
| Rupatadine Fumarate | Rupatadine (UR-12592) Fumarate is a potent, orally active and long-lasting dual PAF/H1 antagonist, with K i s of 0.55 μM and 0.1 μM, respectively. Rupatadine Fumarate can be used for the research of allergic rhinitis and urticaria [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: UR-12592 Fumarate. CAS No. 182349-12-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-13511A. | |
| RuPhos | RuPhos is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 787618-22-8. Pack Sizes: 5 g; 10 g; 25 g. Product ID: HY-W007432. | |
| Rupintrivir | Rupintrivirvr (AG7088), an antiviral agent, is a potent, selective and irreversible inhibitor of human rhinovirus (HRV) 3C protease. Rupintrivirvr inhibits replication of a panel of 48 different HRV serotypes in H1-HeLA and MRC-5 cell protection assays, with a mean EC 50 of 0.023 μM. Rupintrivirvr shows immune-modulatory effect [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AG7088. CAS No. 223537-30-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-106161. | |
| Ruplizumab | Ruplizumab (BG 9588) is a humanized monoclonal anti- CD40L (TNF Receptor) IgG1κ antibody. Ruplizumab has the potential for systemic lupus erythematosus disease research [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BG 9588; Anti-Human CD40L Recombinant Antibody. CAS No. 220651-94-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99315. | |
| Rusalatide acetate | Rusalatide acetate (TP508 amide acetate), a regenerative peptide, mitigates radiation-induced gastrointestinal damage by activating stem cells and preserving crypt integrity [1]. Uses: Scientific research. Group: Peptides. Alternative Names: TP508 amide acetate. CAS No. 875455-82-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-105069A. | |
| Ruscogenin | Ruscogenin, an important steroid sapogenin derived from Ophiopogon japonicus , attenuates cerebral ischemia-induced blood-brain barrier dysfunction by suppressing TXNIP/NLRP3 inflammasome activation and the MAPK pathway. Ruscogenin exerts significant anti-inflammatory and anti-thrombotic activities. Ruscogenin has orally bioactivity [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 472-11-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg. Product ID: HY-N0496. | |
| Rusfertide | Rusfertide is a peptide mimetic of natural hepcidin, which targets and degrades ferroportin , reduces serum iron and transferrin-saturation, and thus regulates the production of red blood cells. Rusfertide ameliorates the polycythemia vera, β-thalassemia and hereditary hemochromatosis [1] [2]. Uses: Scientific research. Group: Peptides. Alternative Names: PTG-300. CAS No. 1628323-80-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P10272. | |
| RU-SKI 43 hydrochloride | RU-SKI 43 hydrochloride is a potent and selective Hedgehog acyltransferase (Hhat) inhibitor with an IC 50 of 850 nM. RU-SKI 43 hydrochloride reduces Gli-1 activation through Smoothened-independent non-canonical signaling and decreases Akt and mTOR pathway activity. RU-SKI 43 hydrochloride has anti-cancer activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1782573-67-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-18366A. | |
| Rutaecarpine | Rutaecarpine, an alkaloid of Evodia rutaecarpa , is an inhibitor of COX-2 with an IC 50 value of 0.28 μM. Uses: Scientific research. Group: Natural products. Alternative Names: Rutecarpine. CAS No. 84-26-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0147. | |
| Ruthenium red | Ruthenium red (Ammoniated ruthenium oxychloride) is a polycationic dye widely used for electron microscopy (EM) of cells, tissues and vegetative bacteria. Ruthenium red strongly reacts with phospholipids and fatty acids and binds to acidic mucopolysaccharides. Ruthenium red is a L-type calcium current (ICa) blocker[1][2]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Ammoniated ruthenium oxychloride. CAS No. 11103-72-3. Pack Sizes: 100 mg; 500 mg. Product ID: HY-103311. | |
| Rutin | Rutin (Rutoside) is a flavonoid found in many plants and shows a wide range of biological activities including anti-inflammatory, antidiabetic, antioxidant, neuroprotective, nephroprotective, hepatoprotective and reducing Aβ oligomer activities. Rutin is also a CBR1 inhibitor, which can cross the blood brain barrier. Rutin attenuates vancomycin-induced renal tubular cell apoptosis via suppression of apoptosis, mitochondrial dysfunction, and oxidative stress [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. Alternative Names: Rutoside; Quercetin 3-O-rutinoside. CAS No. 153-18-4. Pack Sizes: 10 mM * 1 mL; 500 mg; 5 g; 10 g. Product ID: HY-N0148. | |
| Rutin hydrate | Rutin (Rutoside) hydrate is a flavonoid found in many plants and shows a wide range of biological activities including anti-inflammatory, antidiabetic, antioxidant, neuroprotective, nephroprotective, hepatoprotective and reducing Aβ oligomer activities. Rutin hydrate can cross the blood brain barrier. Rutin hydrate attenuates vancomycin-induced renal tubular cell apoptosis via suppression of apoptosis, mitochondrial dysfunction, and oxidative stress [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Rutoside hydrate; Quercetin 3-O-rutinoside hydrate. CAS No. 207671-50-9. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-N0148A. | |
| Rutin (Standard) | Rutin (Standard) is the analytical standard of Rutin. This product is intended for research and analytical applications. Rutin (Rutoside) is a flavonoid found in many plants and shows a wide range of biological activities including anti-inflammatory, antidiabetic, antioxidant, neuroprotective, nephroprotective, hepatoprotective and reducing Aβ oligomer activities. Rutin is also a CBR1 inhibitor, which can cross the blood brain barrier. Rutin attenuates vancomycin-induced renal tubular cell apoptosis via suppression of apoptosis, mitochondrial dysfunction, and oxidative stress [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. CAS No. 153-18-4. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-N0148R. | |
| Rutin trihydrate | Rutin (Rutoside) trihydrate is a multifunctional natural flavonoid glycoside. Rutin trihydrate has been demonstrating excellent antioxidant, anti-inflammatory, anti-diabetic, and anti-carcinogenic properties. Cardioprotective and neuroprotective activities [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Rutoside trihydrate; Quercetin 3-O-rutinoside trihydrate. CAS No. 250249-75-3. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-W013075. | |
| Ruxolitinib | Ruxolitinib (INCB18424) is an orally active and selective JAK1/2 inhibitor with IC 50 s of 3.3 nM and 2.8 nM in cell-free assays, and has 130-fold selectivity for JAK1/2 over JAK3 [1]. Ruxolitinib induces autophagy and kills tumor cells through toxic mitophagy [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: INCB18424. CAS No. 941678-49-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-50856. | |
| Ruxolitinib phosphate | Ruxolitinib phosphate (INCB018424 phosphate) is a potent JAK1/2 inhibitor with IC 50 s of 3.3 nM/2.8 nM, respectively, showing more than 130-fold selectivity over JAK3. Uses: Scientific research. Group: Signaling pathways. Alternative Names: INCB018424 phosphate. CAS No. 1092939-17-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-50858. | |
| Ruxolitinib (S enantiomer) | Ruxolitinib (S enantiomer) (S-Ruxolitinib) is the S-enantiomer of Ruxolitinib (HY-50856). Ruxolitinib (S enantiomer) is an orally active, potent JAK inhibitor[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: S-Ruxolitinib; S-INCB18424. CAS No. 941685-37-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-50856A. | |
| (R)-Verapamil hydrochloride | (R)-Verapamil hydrochloride ((R)-(+)-Verapamil hydrochloride) is an orally active P-Glycoprotein inhibitor. (R)-Verapamil hydrochloride blocks MRP1 mediated transport. (R)-Verapamil hydrochloride induces Apoptosis and inhibits L-type calcium channels BZPcc, DHPcc and PLLcc. (R)-Verapamil hydrochloride has anti-septic shock and anti-diabetic effects [1] [2] [3] [4] [5] [6] [7]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (R)-(+)-Verapamil hydrochloride. CAS No. 38176-02-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-135336. | |
| RVX-297 | RVX-297 is a potent, orally active BET bromodomain inhibitor with selectivity for BD2. RVX-297 shows IC50s of 0.08, 0.05, and 0.02 ?M for BRD2(BD2), BRD3(BD2), and BRD4(BD2), respectively. RVX-297 suppresses inflammatory gene expression in multiple immune cell types. RVX-297 is effective in acute inflammation and autoimmunity models[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1044871-04-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114504. | |
| RW3 | RW3 is a small cationic hexapeptide with amphiphilic properties. RW3 targets the plasma membrane of bacteria and works by inhibiting cell respiration and cell wall synthesis. RW3 shows high biological activity against gram-positive bacteria and does not show significant cytotoxic or hemolytic effects in previous studies. RW3 quickly kills 97% of the initial colony forming units (CFU) within 10 minutes at twice the minimum inhibitory concentration ( MIC ). RW3 can be used in antimicrobial and antifungal studies [1]. Uses: Scientific research. Group: Peptides. CAS No. 359632-11-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P10281. | |
| RX-3117 | RX-3117 (TV-1360) is a potent and orally active anticancer and antimetabolite agent. RX-3117 inhibits DNA methyltransferase 1 (DNMT1). RX-3117 shows antiproliferative and anti-tumour activity. RX-3117 induces cell cycle arrest at S phase and apoptosis [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TV-1360; Fluorocyclopentenylcytosine. CAS No. 865838-26-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-15228. | |
| Ryanodine | Ryanodine is a cell permeant ryanodine receptor modulator. Ryanodine can either stimulate or inhibit Ryanodine-mediated Ca 2+ release depending on its concentrations. Poisonous diterpenoid found in Ryania speciosa. Uses: Scientific research. Group: Natural products. CAS No. 15662-33-6. Pack Sizes: 1 mg. Product ID: HY-103306. | |
| S0456 | S0456 is a raw material that plays a crucial role in the construction of the folate receptor-targeted near-infrared dye OTL 38 (HY-139579). S0456 is connected to the modified folic acid to form OTL 38, endowing OTL 38 with good optical properties, high affinity, and specificity. S0456 can be used in the research of tumor optical imaging agents[1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 1252007-83-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-D1716. | |
| S07-2010 | S07-2010 is a potent pan-AKR1C (aldo-keto reductase family 1 member C) inhibitor, with IC50 values of 0.19, 0.36, 0.47, and 0.73 ?M for AKR1C3, AKR1C4, AKR1C1 and AKR1C2, respectively. S07-2010 induces apoptosis in A549/DDP cells. S07-2010 strengthens the cytotoxicity of chemotherapeutic agents in drug-resistant cells. S07-2010 significantly inhibits the proliferation of drug-resistant cells[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1223194-71-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-150644. | |
| (S)-10-Hydroxycamptothecin | (S)-10-Hydroxycamptothecin (10-HCPT;10-Hydroxycamptothecin) is a DNA topoisomerase I inhibitor of isolated from the Chinese plant Camptotheca accuminata. (S)-10-Hydroxycamptothecin exhibits a remarkable apoptosis -inducing effect. (S)-10-Hydroxycamptothecin has the potential for hepatoma, gastric carcinoma, colon cancer and leukaemia treatment [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: 10-HCPT; 10-Hydroxycamptothecin. CAS No. 19685-09-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-N0095. | |
| (S)-[1,1'-Binaphthalene]-2,2'-diamine | (S)-[1, 1'-Binaphthalene]-2, 2'-diamine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: S-(-)-2,2-Diamino-1,1-binaphthyl. CAS No. 18531-95-8. Pack Sizes: 250 mg; 1 g; 5 g. Product ID: HY-W007978A. | |
| S12 | S12 is a mutant RAS peptide containing the Gly (G) to Ser (S12) substitution. The sequence of the peptide is KLVVVGASGVGKS [1]. Uses: Scientific research. Group: Peptides. CAS No. 257872-93-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P2361. | |
| (S)-(+)-1,2-Propanediol | (S)-(+)-1,2-Propanediol is an endogenous metabolite. Uses: Scientific research. Group: Natural products. CAS No. 4254-15-3. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-79334. | |
| S130 | S130 is a high affinity, selective inhibitor of ATG4B (a major cysteine protease) with an IC 50 of 3.24 μM. S130 suppresses autophagy flux [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1160852-22-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-112818. | |
| S-14506 hydrochloride | S-14506 hydrochloride is a potent 5-HT1A agonist, as well as 5-HT 2A/2C antagonist. S-14506 hydrochloride displays dopamine antagonist properties by blocking dopamine D2 receptors. S-14506 hydrochloride inhibits the in vivo binding of [3H]raclopride in striatum and olfactory bulbs. S-14506 hydrochloride has the potential for the research of anxiolytic agent [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 286369-38-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110024. | |
| S-15535 | S-15535 is a highly selective 5-HT 1A receptor ligand. S-15535 is an antagonist of postsynaptic 5-HT 1A receptors and an agonist of presynaptic 5-HT 1A receptors. S-15535 can be used in research on psychiatric disorders, such as anti-anxiety [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 146998-34-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116076. | |
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