MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Fenoterol hydrobromide | Fenoterol hydrobromide (Th-1165a), a sympathomimetic agent, is a selective and orally active β2-adrenoceptor agonist. Fenoterol hydrobromide is an effective bronchodilator and can be used for bronchospasm associated with asthma, bronchitis and other obstructive airway diseases research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Th-1165a; Phenoterol hydrobromide. CAS No. 1944-12-3. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B0976A. |  |
| Fenoverine | Fenoverine (Spasmopriv) is an antispasmodic agent and inhibits calcium channel currents [1]. Fenoverine induces rhabdomyolysis [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Spasmopriv. CAS No. 37561-27-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107349. | |
| Fenoxaprop-P-ethyl | Fenoxaprop-P-ethyl is a phenoxy propionic acid herbicide with a heterocyclic epoxide structure. Uses: Scientific research. Group: Signaling pathways. CAS No. 71283-80-2. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g; 10 g. Product ID: HY-B2013. | |
| Fenoxaprop-P-ethyl (Standard) | Fenoxaprop-P-ethyl (Standard) is the analytical standard of Fenoxaprop-P-ethyl. This product is intended for research and analytical applications. Uses: Scientific research. Group: Signaling pathways. CAS No. 71283-80-2. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-B2013R. | |
| Fenoxycarb | Fenoxycarb, a juvenile hormone, is an insecticide and can be used for agricultural pest control [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 72490-01-8. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-122062. | |
| Fenpropathrin | Fenpropathrin is a synthetic pyrethroid insecticide in agriculture. Fenpropathrin may induces parkinsonian symptoms progressively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 39515-41-8. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-123178. | |
| Fenpropidin | Fenpropidin is a sterol biosynthesis inhibitor fungicide [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 67306-00-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126200. | |
| Fenpropimorph | Fenpropimorph is a fungicide that inhibits the sterol pathway. Fenpropimorph inhibits δ8-δ7-sterol isomerase in yeast at low concentrations, with δ14-sterol reductase being blocked at higher levels, preventing the biosynthesis of ergosterol. Fenpropimorph also inhibits sterol synthesis in certain plants and mammalian cells [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 67564-91-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-128033. | |
| Fenretinide | Fenretinide (4-HPR) is a synthetic retinoid deriverative, binding to the retinoic acid receptors ( RAR ) at concentrations necessary to induce cell death. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 4-HPR. CAS No. 65646-68-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15373. | |
| Fenspiride hydrochloride | Fenspiride, an orally active non-steroidal antiinflammatory agent, is an antagonist of H1-histamine receptor. Fenspiride inhibites phosphodiesterase 3 (PDE3), phosphodiesterase 4 (PDE4) and phosphodiesterase 5 (PDE5) activities with -log IC 50 values of 3.44, 4.16 and approximately 3.8, respectively. Fenspiride can be used for the research of respiratory diseases [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 5053-8-7. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-A0027. | |
| Fentiazac | Fentiazac, alkanoic acid derivative, is an orally active non-steroidal anti-inflammatory agent, with analgesic, antipyretic and platelet anti-aggregation activity. Fentiazac can be used to research inflammatory diseases such as rheumatoid arthritis, osteoarthritis and tendinitis [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 18046-21-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-118752. | |
| Fenticonazole Nitrate | Fenticonazole Nitrate is an antifungal imidazole ring derivative. Fenticonazole Nitrate operates via hindering ergosterol integration, and sequentially destructing the cytoplasmatic outer membrane. Fenticonazole Nitrate is effective against Gram-positive bacteria, mycoses, and vaginal candidiasis [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: REC 15-1476. CAS No. 73151-29-8. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0359. | |
| Fentonium bromide | Fentonium bromide is an anti-ulcerogenic, anticholinergic and antispasmodic agent. Fentonium bromide can be used in the research of neurological conditions [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 5868-6-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122520. | |
| Fenvalerate | Fenvalerate is a potent protein phosphatase 2B (calcineurin) inhibitor with an IC 50 of 2-4 nM for PP2B-A&alpha. Fenvalerate is a pyrethroid ester insecticide and acaricide [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 51630-58-1. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-B2006. | |
| Feprazone | Feprazone (DA2370; Prenazone), an analogue of Phenylbutazone (HY-B0230), is a nonsteroidal anti-inflammatory agent with analgesic and antipyretic activities. Feprazone acts by inhibiting the activity of cyclooxygenase (COX)-2. Feprazone ameliorates free fatty acid (FFA)-induced oxidative stress by reducing the production of mitochondrial reactive oxygen species (ROS). Feprazone can decrease the expression of MMP-2 and MMP-9. Besides, Feprazone can suppress adipogenesis and increase lipolysis in differentiating 3 T3-L1 cells. Feprazone also can be used to research atherosclerosis and obesity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DA2370; Prenazone; Zepelin. CAS No. 30748-29-9. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-114911. | |
| Ferric citrate | Ferric citrate (Iron(III) citrate), an orally active iron supplement, is an efficacious phosphate binder. Ferric citratee can be used for iron deficiency anemia and chronic kidney disease (CKD) research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Iron(III) citrate; Zerenex. CAS No. 3522-50-7. Pack Sizes: 100 mg. Product ID: HY-N1428C. | |
| Ferric citrate hydrate | Ferric citrate hydrate, an orally active iron supplement, is an efficacious phosphate binder. Ferric citrate hydrate can be used for iron deficiency anemia and chronic kidney disease (CKD) research [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 2338-5-8. Pack Sizes: 25 g; 50 g; 100 g. Product ID: HY-47030. | |
| Ferric maltol | Ferric maltol is an orally active monovalent iron (Fe 3+ ) complex. Ferric maltol is used in the study of iron deficiency anemia in inflammatory bowel disease [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 33725-54-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108017. | |
| Ferric nitrilotriacetate | Ferric nitrilotriacetate (Fe-NTA), a complexation of nitriloacetic acid with iron, is a highly reactive compound used to induce degenerative disorders through oxidative stress (OS). Ferric nitrilotriacetate is also used in several studies to induce hyperglycemia, glycosuria, and both renal and liver carcinogenesis[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 16448-54-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145157. | |
| Ferric pyrophosphate | Ferric pyrophosphate is a kind of biological materials or organic compounds that are widely used in life science research [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 10058-44-3. Pack Sizes: 25 g. Product ID: HY-B1648. | |
| Ferron | Ferron (8-Hydroxy-7-iodo-5-quinolinesulfonic acid) has antiseptic and antifungal activity. Ferron can prevent skin and mucosa bacterial irritations and inflammations [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 8-Hydroxy-7-iodo-5-quinolinesulfonic acid. CAS No. 547-91-1. Pack Sizes: 10 mM * 1 mL; 100 mg; 5 g. Product ID: HY-W103183. | |
| FerroOrange | FerroOrange is a Fe2+ selective probe with an excitation wavelength of 543 nm and an emission wavelength of 580 nm. FerroOrange emits fluorescence after binding to intracellular Fe2+, thereby achieving specific labeling of Fe2+. FerroOrange is used to detect the content and distribution of Fe2+ in cells[1]. Uses: Scientific research. Group: Fluorescent dye. Pack Sizes: 24 ?g. Product ID: HY-D1913. | |
| Ferroportin-IN-1 | Ferroportin-IN-1 is a ferroportin inhibitor extracted from patent WO2020123850A1 compound 23. Ferroportin-IN-1 can be used for the research of diseases caused by a lack of hepcidin or iron metabolism disorders [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2443432-65-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-145965. | |
| Ferroquine | Ferroquine (Ferrochloroquine), a ferrocenyl analogue of Chloroquine, is an antimalarial agent. Ferroquine shows parasiticidal effect on Plasmodium by inducing oxidative stress and the subsequent destruction of the membrane [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ferrochloroquine; SSR97193. CAS No. 185055-67-8. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19364. | |
| Ferrostatin-1 | Ferrostatin-1 (Fer-1), a potent and selective ferroptosis inhibitor, suppresses Erastin-induced ferroptosis in HT-1080 cells (EC50=60 nM). Ferrostatin-1, a synthetic antioxidant, acts via a reductive mechanism to prevent damage to membrane lipids and thereby inhibits cell death. Ferrostatin-1 exhibits antifungal activity[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Fer-1. CAS No. 347174-05-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100579. | |
| Ferrous bisglycinate | Ferrous bisglycinate is an orally active iron fortificants and therapeutic iron supplements. Ferrous bisglycinate can be used for the research of iron deficiency anemia [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 20150-34-9. Pack Sizes: 500 mg. Product ID: HY-130078. | |
| Ferrozine | Ferrozine is a spectrophotometric reagent for iron ions, can react with divalent Fe to form a stable magenta complex species. The complex has an absorption peak at 562 nm[1][2]. Ferrozine-based colorimetric assays can quantify iron in cells[3]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 69898-45-9. Pack Sizes: 100 mg; 250 mg; 500 mg. Product ID: HY-137805. | |
| Fertirelin | Fertirelin is a GnRH and LH-RH analogue. Fertirelin can be used of the study for reversing cow follicular cysts [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 38234-21-8. Pack Sizes: 2 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-P0053. | |
| Ferulenol | Ferulenol, a sesquiterpene prenylated coumarin derivative, specifically inhibits succinate ubiquinone reductase at the level of the ubiquinonecycle. Ferulenol shows good antimycobacterial activity and haemorrhagic action [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 6805-34-1. Pack Sizes: 5 mg. Product ID: HY-129605. | |
| Ferulic acid | Ferulic acid is a novel fibroblast growth factor receptor 1 ( FGFR1 ) inhibitor with IC 50 s of 3.78 and 12.5 μM for FGFR1 and FGFR2 , respectively. Uses: Scientific research. Group: Natural products. Alternative Names: Coniferic acid. CAS No. 1135-24-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 1 g; 5 g. Product ID: HY-N0060. | |
| Ferulic acid methyl ester | Ferulic acid methyl ester (Methyl ferulate) is a derivative of ferulic acid, isolated from Stemona tuberosa , with anti-inflammatory and antioxidant properties [1] [2]. Ferulic acid methyl ester is a cell membrane and brain permeable compound, shows free radical scavenging ability, used in the research of neurodegenerative disorders [1]. Ferulic acid methyl ester inhibits COX-2 expression, blocks p-p38 and p-JNK in primary bone marrow derived-macrophages [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Methyl ferulate. CAS No. 2309-7-1. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-W018643. | |
| Ferulic acid sodium | Ferulic acid sodium is a novel fibroblast growth factor receptor 1 ( FGFR1 ) inhibitor with IC 50 s of 3.78 and 12.5 μM for FGFR1 and FGFR2 , respectively. Uses: Scientific research. Group: Natural products. Alternative Names: Coniferic acid sodium. CAS No. 24276-84-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 1 g; 5 g. Product ID: HY-N0060A. | |
| Ferutinin | Ferutinin, a natural terpenoid compound, is an estrogen receptor ERα agonist and estrogen ERβ-receptor agonist/antagonist with IC 50 s of 33.1 nM and 180.5 nM, respectively. Ferutinin acts as an electrogenic Ca 2+ -ionophore that increases calcium permeability of lipid bilayer membranes, mitochondria. Ferutinin possesses estrogenic, antitumor, antibacterial and antiinflammatory activities [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 41743-44-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-125703. | |
| Fesoterodine | Fesoterodine is an orally active, nonsubtype selective, competitive muscarinic receptor (mAChR) antagonist with pK i values of 8.0, 7.7, 7.4, 7.3, 7.5 for M1, M2, M3, M4, M5 receptors, respectively. Fesoterodine is used for the overactive bladder (OAB) [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 286930-02-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-70053. | |
| Fesoterodine fumarate | Fesoterodine Fumarate is an orally active, nonsubtype selective, competitive muscarinic receptor (mAChR) antagonist with pK i values of 8.0, 7.7, 7.4, 7.3, 7.5 for M1, M2, M3, M4, M5 receptors, respectively. Fesoterodine Fumarate is used for the overactive bladder (OAB) [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 286930-03-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-A0030. | |
| Fesoterodine L-mandelate | Fesoterodine L-mandelate is an orally active, nonsubtype selective, competitive muscarinic receptor (mAChR) antagonist with pK i values of 8.0, 7.7, 7.4, 7.3, 7.5 for M1, M2, M3, M4, M5 receptors, respectively. Fesoterodine L-mandelate is used for the overactive bladder (OAB) [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1206695-46-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-70053A. | |
| FeTMPyP | FeTMPyP is an orally active peroxynitrite (ONOO ) scavenger. FeTMPyP reduces nitrative stress and increases autophagy. FeTMPyP reduces PARP over-activation and neuroinflammation in chronic constriction injury (CCI)-induced rats, and ameliorates functional, behavioral and biochemical deficits [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 133314-07-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-120380. | |
| FeTPPS | FeTPPS, a 5,10,15,20-tetrakis (4-sulfonatophenyl) porphyrin iron III chloride peroxynitrite decomposition catalyst, possesses evident neuroprotective effects in a experimental model of spinal cord damage [1]. FeTPPS acts as a peroxynitrite scavenger and anti-nitrating agent in vivo. FeTPPS reduces nitric oxide ( NO ) production and apoptosis process [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 90384-82-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-131697. | |
| Fevipiprant | Fevipiprant (QAW039, NVP-QAW039) is s an orally active, selective, reversible prostaglandin D2 (DP2) receptor antagonist with an K d value of 1.14 nM. Fevipiprant has the potential for the research of bronchial asthma [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: QAW039; NVP-QAW039. CAS No. 872365-14-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16768. | |
| Fexagratinib | Fexagratinib (AZD4547; ADSK091) is a potent inhibitor of the FGFR family with IC50s of 0.2 nM, 2.5 nM, 1.8 nM, and 165 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AZD4547; ADSK091. CAS No. 1035270-39-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-13330. | |
| Fexaramine | Fexaramine is a potent and selective FXR agonist with an EC 50 of 25 nM. Fexaramine has no activity against hRXRα, hPPARαγδ, mPXR, hPXR, hLXRα, hTRβ, hRARβ, mCAR, mERRγ, and hVDR receptors [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 574013-66-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-10912. | |
| Fexinidazole | Fexinidazole (HOE 239) is an orally active, potent nitroimidazole antitrypanosomal agent. Fexinidazole shows trypanocidal activity against T. brucei subspecies and strains with IC 50 s of 0.7-3.3 μM (0.2-0.9 μg/ml). Fexinidazol has the potential for human sleeping sickness (HAT) caused by infection with T. brucei [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HOE 239. CAS No. 59729-37-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13801. | |
| Fexofenadine | Fexofenadine (MDL-16455) is an orally active and nonsedative H1 receptor antagonist. Fexofenadine can be used in allergic rhinitis and chronic idiopathic urticarial research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MDL-16455; Terfenadine carboxylate. CAS No. 83799-24-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0801. | |
| Fexofenadine hydrochloride | Fexofenadine (MDL-16455) hydrochloride is an orally active and nonsedative H 1 receptor antagonist. Fexofenadine hydrochloride can be used in allergic rhinitis and chronic idiopathic urticarial research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MDL-16455 hydrochloride; Terfenadine carboxylate hydrochloride. CAS No. 153439-40-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0801A. | |
| Fezagepras | Fezagepras (Setogepram) acts as an orally active agonist for GPR40 and as an antagonist or inverse agonist for GPR84 [1]. Fezagepras decreases renal, liver and pancreatic fibrosis [1] [2]. Fezagepras exerts anti-fibrotic, anti-inflammatory and anti-proliferative actions [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Setogepram; PBI-4050. CAS No. 1002101-19-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100775A. | |
| Fezagepras sodium | Fezagepras (Setogepram) sodium acts as an orally active agonist for GPR40 and as an antagonist or inverse agonist for GPR84 [1]. Fezagepras sodium decreases renal, liver and pancreatic fibrosis [1] [2]. Fezagepras sodium exerts anti-fibrotic, anti-inflammatory and anti-proliferative actions [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Setogepram sodium; PBI-4050 sodium. CAS No. 1254472-97-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100775. | |
| Fezakinumab | Fezakinumab is an interleukin-22 (IL-22) monoclonal antibody. Fezakinumab can be used for the research of inflammatory disease, such as psoriasis and rheumatoid arthritis [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ILV 094. CAS No. 1007106-86-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99244. | |
| Fezolinetant | Fezolinetant is an antagonist of the neurokinin 3 receptor (NK3R) , used for the treatment of menopausal hot flushes. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ESN-364. CAS No. 1629229-37-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19632. | |
| FFN511 | FFN511 is a potent fluorescent false neurotransmitters (FFNs) that targets neuronal vesicular monoamine transporter 2 (VMA T2). FFN511 inhibits serotonin binding to VMA T2 -containing membranes with an IC 50 of 1 μM. FFN511 directly images the dynamics of release during exocytosis, can be used to label dopamine terminals in live cortical-striatalacute slices [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1004548-96-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103465. | |
| FG-2216 | FG-2216 (IOX3) is a potent and orally active inhibitor of HIF prolyl hydroxylase-2 (PHD2) , with an IC 50 of 3.9 μM. FG-2216 induces robust erythropoietin and modest fetal hemoglobin in vivo [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IOX3; YM311. CAS No. 223387-75-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15641. | |
| FG-3019 | FG-3019 (Pamrevlumab) is a recombinant human antibody that binds to connective tissue growth factor (CTGF). FG-3019 can be used for the research of idiopathic pulmonary fibrosis (IPF)[1][2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Pamrevlumab; Anti-Human CTGF Recombinant Antibody. CAS No. 946415-13-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99288. | |
| FG 7142 | FG 7142 (ZK 39106; LSU-65), a non-selectively benzodiazepine inverse agonist, has high affinity for the α1 subunit-containing GABAA receptor ( K i =91 nM). FG 7142 (ZK 39106; LSU-65) also modulates GABA-induced chloride flux at GABAA receptors expressing the α1 subunit ( EC 50 = 137 nM). FG 7142 (ZK 39106; LSU-65) can increase tyrosine hydroxylation and cause upregulation of β-adrenoceptors in mouse cerebral cortex [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ZK 39106; LSU-65. CAS No. 78538-74-6. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-100991. | |
| FGFR2-IN-2 | FGFR2-IN-2 (Compound 38) is a selective FGFR2 inhibitor with IC50s of 389, 29, and 758 nM for FGFR1, FGFR2, and FGFR3, respectively[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2677709-81-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145231. | |
| FGFR-IN-1 | FGFR-IN-1 is a potent FGFR inhibitor with an IC 50 of <100 nM for FGFR1, FGFR2, and FGFR3, respectively (patent US20130338134A1, example 219) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1513860-41-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145043. | |
| FGIN 1-27 | FGIN 1-27, an indoleacetamide, is a specific peripheral benzodiazepine receptor (PBR) ligand with a K i of 5.0 nM. FGIN 1-27 can penetrate the blood brain barrier (BBB). FGIN 1-27 inhibits the onset of Isoniazid-induced convulsions [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 142720-24-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101059. | |
| FGTI-2734 | FGTI-2734 is a RAS C-terminal mimetic dual farnesyl transferase (FT) and geranylgeranyl transferase-1 (GGT-1) inhibitor with IC50s of 250 nM and 520 nM for FT and GGT-1, respectively. FGTI-2734 can prevent membrane localization of KRAS, hence solving KRAS resistance problem and thwarting mutant KRAS patient-derived pancreatic tumors[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1247018-19-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128350. | |
| FH1 | FH1 (NSC 12407) enhances hepatocyte functions, and promotes the differentiation of induced pluripotent stem (iPS)-derived hepatocytes toward a phenotype more mature and the maturation of well-differentiated cultures of hepatocyte-like cells (iHeps) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NSC 12407; BRD-K4477. CAS No. 2719-5-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12346. | |
| FH535 | FH535 is an inhibitor of Wnt/?-catenin and PPAR with anti-tumor activities[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 108409-83-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15721. | |
| FHD-609 | FHD-609 is a PROTAC degrader and inhibitor of BRD9 ( Bromodomain-containing protein 9 ). FHD-609 targets to ncBAF , can be used for research of wide range of cancers that contain a mutation in a BAF complex subunit. FHD-609 in combination with Telomelysin or INO5401, may play a role in adrenocortical carcinoma (ACC) treatment. (Blue: BRD9 ligand-6 (HY-49393), Black: linker (HY-168309); Pink: (S)-Deoxy-thalidomide-Br (HY-168308) ) [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2676211-64-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153367. | |
| FHT-1015 | FHT-1015 is a selective SMARCA4 (IC50 = 4 nM) and SMARCA2 (IC50 = 5 nM) (also known as BRG1 and BRM) inhibitor. FH-1015 is an allosteric inhibitor that causes conformation change in the BRG1/BRM protein upon interaction with an allosteric site, inhibiting ATPase activity. FH-1015 interferes with tumor cell growth and migration. FH-1015 can be studied in research for uveal melanoma and hematologic cancer[1][2][3][4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2368903-18-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144896. | |
| FHT-2344 | FHT-2344 is a SMARCA4/SMARCA2 ATPase inhibitor with IC 50 values of 0.026 μM and 0.013 μM, respectively. FHT-2344 has anticancer activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2468058-90-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-149458. | |
| Fialuridine | Fialuridine is a nucleoside analog with antiviral activity [1]. Fialuridine shows anti-orthopoxvirus activity [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FIAU; DRG-0098; NSC 678514. CAS No. 69123-98-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-118122. | |
| Fianlimab | Fianlimab (REGN3767) is a human monoclonal antibody that targets the immune checkpoint receptor LAG-3 on T cells and has anti-tumour activity [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: REGN3767. CAS No. 2126132-98-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99617. | |
| Fiboflapon | Fiboflapon (GSK2190915; AM-803) is a potent and orally bioavailable 5-lipoxygenase-activating protein ( FLAP ) inhibitor with a potency of 2.9 nM in FLAP binding, an IC 50 of 76 nM for inhibition of LTB4 in human blood [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GSK2190915; AM-803. CAS No. 936350-00-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15874. | |
| Fiboflapon sodium | Fiboflapon sodium (GSK2190915; AM-803) is a potent and orally bioavailable 5-lipoxygenase-activating protein ( FLAP ) inhibitor with a potency of 2.9 nM in FLAP binding, an IC 50 of 76 nM for inhibition of LTB4 in human blood [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GSK2190915 sodium salt; AM-803 sodium. CAS No. 1196070-26-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15874A. | |
| Fibrin | Fibrin, isolated from bovine blood, is an insoluble protein produced in response to bleeding. Fibrin is the major component of the blood clot and is used for coagulation [1]. Uses: Scientific research. Group: Natural products. CAS No. 9001-31-4. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-B0665. | |
| Fibrinogen Binding Inhibitor Peptide | Fibrinogen Binding Inhibitor Peptide is a dodecapeptide (HHLGGAKQAGDV, H12), which is a fibrinogen γ-chain carboxy-terminal sequence (γ400-411). Fibrinogen Binding Inhibitor Peptide is a specific binding site of the ligand for activated glycoprotein (GP) IIb/IIIa. Uses: Scientific research. Group: Peptides. CAS No. 89105-94-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1507. | |
| Fibrinogen-Binding Peptide | Fibrinogen-Binding Peptide (designed by anticomplementarity hypothesis) is a presumptive peptide mimic of the vitronectin binding site on the fibrinogen receptor. Fibrinogen-Binding Peptide binds fibrinogen and inhibits both the adhesion of platelets to fibrinogen and platelet aggregation, and also inhibits the adhesion of platelets to vitronectin [1]. Uses: Scientific research. Group: Peptides. CAS No. 137235-80-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1741. | |
| Fibrinogen (Bovine) | Fibrinogen (Bovine) is a selective proteolytic molecule that can be activated by thrombin to assemble fibrin clots. Fibrinogen can regulate the activation of NF-KB in endothelial cells and upregulate the expression of inflammatory chemokines MCP-1 and MCP-1. Fibrinogen plays a key role in blood clotting, thrombosis, atherosclerosis and the pathological development of venous grafts, and can be used in the study of blood clotting and vascular diseases [1] [2] [3]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 9001-32-5. Pack Sizes: 50 mg; 100 mg. Product ID: HY-125864. | |
| Fibrinopeptide A, human TFA | Fibrinopeptide A, human TFA is a 16-residue short polypeptide cleaved from fibrinogen by thrombin. Fibrinopeptide A, human locates at the NH 2 -termini of the Aα chain [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Human fibrinopeptide A TFA. CAS No. 61533-47-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1538A. | |
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