MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Imazapic | Imazapic is a selective herbicide used to control perennial grasses and some broadleaf weeds. Uses: Scientific research. Group: Signaling pathways. CAS No. 104098-48-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B1860. |  |
| Imazethapyr | Imazethapyr is an imidazolinone herbicide used in crops. Imazethapyr can protect crops from damage by weeds and annual grasses [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 81335-77-5. Pack Sizes: 10 mM * 1 mL; 50 mg. Product ID: HY-133188. | |
| IMD-0354 | IMD-0354 (IKK2 Inhibitor V) is a selective IKKβ inhibitor which inhibits NF-κB activity [1]. IMD0354 inhibits TNF-α induced NF-κB transcription activity with an IC 50 of 1.2 uM [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IKK2 Inhibitor V. CAS No. 978-62-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10172. | |
| Imdevimab | Imdevimab (REGN10987) is a human monoclonal antibody to target SARS-CoV-2 virus, which causes COVID-19. Imdevimab lacks efficacy against COVID-19 variants. Imdevimab can be used in combination with Casirivimab (HY-P99341), it reduces viral load and improves diseases [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: REGN10987. CAS No. 2415933-40-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99342. | |
| Imeglimin hydrochloride | Imeglimin hydrochloride (EMD 387008) is an oral glucose-lowering agent. Imeglimin also reduces reactive oxygen species ( ROS ) production, increases mitochondrial DNA and improves mitochondrial function [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EMD 387008 hydrochloride. CAS No. 775351-61-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14771A. | |
| Imepitoin | Imepitoin (AWD 131-138) is a new low-affinity partial benzodiazepine receptor agonist with potent anticonvulsant and anxiolytic properties in rodent models. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AWD 131-138. CAS No. 188116-07-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14953. | |
| Imexon | Imexon (BM 06002) is an iminopyrrolidone aziridine with anti-cancer activity. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BM 06002. CAS No. 59643-91-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-15385. | |
| Imgatuzumab | Imgatuzumab (RG 7160) is a humanized monoclonal antibody against the EGFR. Imgatuzumab acts as an immunomodulator. Imgatuzumab can be used in research of cancer [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: RG 7160; RO 5083945; Anti-EGFR Recombinant Antibody. CAS No. 959963-46-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99295. | |
| Imidacloprid | Imidacloprid is an effective and widely used neonicotinoid pesticide to control pests of cereals, vegetables, tea and cotton. Uses: Scientific research. Group: Signaling pathways. CAS No. 138261-41-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg. Product ID: HY-B0838. | |
| Imidafenacin | Imidafenacin (KRP-197; ONO-8025) is a potent and selective inhibitor of M3 receptors. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KRP-197; ONO-8025. CAS No. 170105-16-5. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0662. | |
| Imidapril | Imidapril (TA-6366 free base) is an orally active angiotensin-converting enzyme (ACE) and MMP-9 inhibitor. Imidapril suppresses the conversion of angiotensin I to angiotensin II and thereby reduces total peripheral resistance and systemic blood pressure. Imidapril can be used for hypertension, type 1 diabetic, nephropathy and chronic heart failure research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TA-6366 free base. CAS No. 89371-37-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-B1451A. | |
| Imidapril hydrochloride | Imidapril hydrochloride (TA-6366) is an orally active angiotensin-converting enzyme (ACE) and MMP-9 inhibitor. Imidapril hydrochloride suppresses the conversion of angiotensin I to angiotensin II and thereby reduces total peripheral resistance and systemic blood pressure. Imidapril hydrochloride can be used for hypertension, type 1 diabetic, nephropathy and chronic heart failure research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TA-6366. CAS No. 89396-94-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1451. | |
| Imidazenil | Imidazenil is a partial positive allosteric modulator of GABA A receptors with anxiolytic, antipanic and anticonvulsant activities. Uses: Scientific research. Group: Signaling pathways. CAS No. 151271-08-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-121393. | |
| Imidazol-1-yl-acetic acid | Imidazol-1-yl-acetic acid is an endogenous metabolite. Uses: Scientific research. Group: Natural products. CAS No. 22884-10-2. Pack Sizes: 500 mg; 1 g. Product ID: HY-W010448. | |
| Imidazole | Imidazole (Glyoxaline; 1,3-Diaza-2,4-cyclopentadiene) is a heterocyclic aromatic compound. Imidazole bearing molecules have been used as corrosion, acetylcholinesterase (AChEI) and xanthine oxidase (XO) inhibitors, performing biological activities such as antifungal, antituberculosis, anti-inflammatory, antioxidant, and analgesic, amongst many others. Imidazole inhibits the enzymatic conversion of the endoperoxides (PGG 2 and PGH 2 ) to thromboxane A2 by platelet microsomes. Imidazole derivatives exhibits inhibition on SARS-CoV-2 3CL Pro enzyme, which is promising for research in the field of Alzheimers disease, gout, COVID-19 and thrombo-embolic disease [1] [2] [3]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Glyoxaline; 1,3-Diaza-2,4-cyclopentadiene. CAS No. 288-32-4. Pack Sizes: 10 mM * 1 mL; 5 g. Product ID: HY-D0837. | |
| Imidazoleacetic acid | Imidazoleacetic acid is an endogenous ligand that stimulates imidazole receptors. Uses: Scientific research. Group: Natural products. Alternative Names: Imidazolyl-4-acetic acid. CAS No. 645-65-8. Pack Sizes: 10 mg; 25 mg; 50 mg. Product ID: HY-113413. | |
| Imidazoleacetic acid hydrochloride | Imidazoleacetic acid hydrochloride is a γ-aminobutyric acid receptor agonist. Imidazoleacetic acid hydrochloride inhibits GABA-T in a non-competitive manner, with a K i value of 0.34 mM. Imidazoleacetic acid hydrochloride increases total free GABA in brain [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Imidazolyl-4-acetic acid hydrochloride. CAS No. 3251-69-2. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-W007686. | |
| Imidazolidinyl urea | Imidazolidinyl urea is a commonly used antibacterial preservative in cosmetics and pharmaceuticals that releases formaldehyde through decomposition. Imidazolidinyl urea can also be used in the preparation of multifunctional hydrogels for the care of infectious wounds. Imidazolidinyl urea has broad-spectrum antibacterial activity, which mainly inhibits the reproduction of gram-negative bacteria and gram-positive bacteria, and restricts the growth of yeast and mold to a certain extent. Imidazolidinyl urea can induce non-histaminergic allergy by MRGPRX2 activation of mast cells [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 39236-46-9. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-B1158. | |
| Imidocarb | Imidocarb is a potent antiprotozoal agent. Imidocarb is active against the parasite B. bovis with an IC 50 of 87 μg/mL [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 27885-92-3. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135611. | |
| Imidocarb dipropionate | Imidocarb dipropionate is a potent antiprotozoal agent. Imidocarb dipropionate is active against the parasite B. bovis with an IC 50 of 87 μg/mL [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 55750-06-6. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-107496. | |
| Iminodiacetic acid | Iminodiacetic acid (IDA) is a chelating agent that strongly binds transition metals [1]. Iminodiacetic acid can be used for removal of toxic metal ions from water [2]. Iminodiacetic acid can serve as a biomarker to potentially predict the severity of ARDS (acute respiratory distress syndrome) [3]. Uses: Scientific research. Group: Natural products. CAS No. 142-73-4. Pack Sizes: 10 mM * 1 mL; 5 g; 10 g. Product ID: HY-W012683. | |
| Iminodibenzyl | Iminodibenzyl is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 494-19-9. Pack Sizes: 10 mM * 1 mL; 25 g. Product ID: HY-B2131. | |
| Iminostilbene | Iminostilbene is a chemical precursor of carbamazepine. Additionally, Iminostilbene is an orally active inhibitor of PKM2 (Pyruvate Kinase M2) and COX2 (Cyclooxygenase-2). Iminostilbene exerts its effects by inhibiting PKM2 and its interaction with HIF-1α and STAT3 , reducing COX2 and iNOS expression, and decreasing LPS-induced release of IL-1β , IL-6 , TNF-α , and MCP-1 , thereby suppressing macrophage-mediated inflammatory responses and improving myocardial ischemia/reperfusion (MI/R) injury. Iminostilbene holds promise for research in inflammation regulation, cardiovascular diseases (such as MI/R injury), and macrophage-mediated immune-related diseases [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 256-96-2. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-N7064. | |
| Imipenem | Imipenem (MK0787), a stable crystalline derivative of thienamycin, is an antibiotic and has the excellent activity against a broad range of gram-positive and gram-negative aerobic and anaerobic bacteria. Imipenem can be used for the research of carbapenem-nonsusceptible and P. aeruginosa biofilm infections [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: N-Formimidoyl thienamycin; MK0787. CAS No. 64221-86-9. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-B1369A. | |
| Imipenem monohydrate | Imipenem monohydrate, a stable crystalline derivative of thienamycin, is an antibiotic and has the excellent activity against a broad range of gram-positive and gram-negative aerobic and anaerobic bacteria. Imipenem monohydrate can be used for the research of carbapenem-nonsusceptible and P. aeruginosa biofilm infections [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: N-Formimidoyl thienamycin monohydrate; MK0787 monohydrate. CAS No. 74431-23-5. Pack Sizes: 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-B1369. | |
| Imipramine | Imipramine is an orally active tertiary amine tricyclic antidepressant. Imipramine is a Fascin1 inhibitor with antitumor activities. Imipramine also inhibits serotonin transporter with an IC 50 value of 32 nM. Imipramine stimulates U-87MG glioma cells autophagy and induces HL-60 cell apoptosis. Imipramine shows neuroprotective and immunomodulatory effects [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 50-49-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1490A. | |
| Imipramine-d4 hydrochloride | Imipramine-d 4 (hydrochloride) is the deuterium labeled Imipramine hydrochloride. Imipramine hydrochloride is an orally active tertiary amine tricyclic antidepressant. Imipramine hydrochloride is a Fascin1 inhibitor with antitumor activities. Imipramine hydrochloride also inhibits serotonin transporter with an IC50 value of 32 nM. Imipramine hydrochloride stimulates U-87MG glioma cells autophagy and induces HL-60 cell apoptosis. Imipramine hydrochloride shows neuroprotective and immunomodulatory effects[1][2][3][4][5][6]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 61361-33-9. Pack Sizes: 1 mg. Product ID: HY-B1490S. | |
| Imipramine hydrochloride | Imipramine hydrochloride is an orally active tertiary amine tricyclic antidepressant. Imipramine hydrochloride is a Fascin1 inhibitor with antitumor activities. Imipramine hydrochloride also inhibits serotonin transporter with an IC 50 value of 32 nM. Imipramine hydrochloride stimulates U-87MG glioma cells autophagy and induces HL-60 cell apoptosis. Imipramine hydrochloride shows neuroprotective and immunomodulatory effects [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 113-52-0. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B1490. | |
| Imiquimod | Imiquimod (R 837), an immune response modifier, is a selective toll like receptor 7 (TLR7) agonist. Imiquimod exhibits antiviral and antitumor effects in vivo. Imiquimod can be used for the research of external genital, perianal warts, cancer and COVID-19 [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R 837. CAS No. 99011-02-6. Pack Sizes: 100 mg; 200 mg; 500 mg. Product ID: HY-B0180. | |
| Imiquimod hydrochloride | Imiquimod hydrochloride (R 837 hydrochloride), an immune response modifier, is a selective toll like receptor 7 (TLR7) agonist. Imiquimod hydrochloride exhibits antiviral and antitumor effects in vivo. Imiquimod hydrochloride can be used for the research of external genital, perianal warts, cancer and COVID-19 [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R 837 hydrochloride. CAS No. 99011-78-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg. Product ID: HY-B0180A. | |
| Imiquimod maleate | Imiquimod maleate (R 837 maleate), an immune response modifier, is a selective toll like receptor 7 (TLR7) agonist. Imiquimod maleate exhibits antiviral and antitumor effects in vivo. Imiquimod maleate can be used for the research of external genital, perianal warts, cancer and COVID-19 [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R 837 maleate. CAS No. 896106-16-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg. Product ID: HY-B0180B. | |
| Imlunestrant | Imlunestrant (LY-3484356) is an orally active, potent and selective estrogen receptor degrader (SERD) with pure antagonistic properties. Imlunestrant results in sustained inhibition of ER-dependent gene transcription and cell growth. Imlunestrant can be used for the research of ER-positive (ER+) advanced breast cancer (aBC) and endometrial endometrioid cancer (EEC) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY-3484356. CAS No. 2408840-26-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-145572. | |
| Imlunestrant tosylate | Imlunestrant (LY-3484356) tosylate is an orally active, potent and selective estrogen receptor degrader (SERD) with pure antagonistic properties. Imlunestrant tosylate results in sustained inhibition of ER-dependent gene transcription and cell growth. Imlunestrant tosylate can be used for the research of ER-positive (ER+) advanced breast cancer (aBC) and endometrial endometrioid cancer (EEC) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY-3484356 tosylate. CAS No. 2408840-41-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-145572A. | |
| IMM-01 | IMM-01 is a mammalian Diaphanous (mDia)-related formins agonist that inhibits DID-DAD (diaphanous inhibitory domain-diaphanous autoregulatory domain) binding with an IC 50 of 140 nM. IMM-01 acts by disrupting the autoinhibitory bond between the DID and DAD domain and thus activates formins. IMM-01 shows anticancer effects [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 218795-74-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124808. | |
| Immepip dihydrobromide | Immepip dihydrobromide is a H3 agonist. Immepip dihydrobromide can reduce cortical histamine release. Immepip dihydrobromide can be used for the research of neurological diseases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 164391-47-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-101321A. | |
| Imofinostat | MPT0E028 is an orally active and selective HDAC inhibitor with IC 50 s of 53.0 nM, 106.2 nM, 29.5 nM for HDAC1, HDAC2 and HDAC6, respectively [1]. MPT0E028 reduces the viability of B-cell lymphomas by inducing apoptosis and possesses potent direct Akt targeting ability and reduces Akt phosphorylation in B-cell lymphoma. MPT0E028 has good anticancer activity [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MPT0E028. CAS No. 1338320-94-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124295. | |
| Imperatorin | Imperatorin is an effective of NO synthesis inhibitor ( IC 50 =9.2 μmol), which also is a BChE inhibitor ( IC 50 =31.4 μmol). Imperatorin is a weak agonist of TRPV1 with EC 50 of 12.6±3.2 μM. Uses: Scientific research. Group: Natural products. Alternative Names: Ammidin. CAS No. 482-44-0. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-N0285. | |
| Importazole | Importazole is a small molecule inhibitor of the nuclear transport receptor importin-&beta. Uses: Scientific research. Group: Signaling pathways. CAS No. 662163-81-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-101091. | |
| IMR-1 | IMR-1 is a novel class of Notch inhibitor targeting the transcriptional activation with an IC 50 of 26 μM. IMR-1 prevents the recruitment of Mastermind-like 1 (Maml1) to the Notch Ternary Complex (NTC) on chromatin, inhibits Notch target gene transcription and dramatically inhibits tumor growth [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 310456-65-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100431. | |
| IMR-1A | IMR-1A, a acid metabolite of IMR-1, is a Notch inhibitor with an IC 50 of 0.5 μM. IMR-1A has a 50-fold increase in potency with respect to IMR-1. IMR-1 can metabolize in vivo to IMR-1A [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 331862-41-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100431A. | |
| Imrecoxib | Imrecoxib (BAP-909) is a novel and selective cyclooxygenase 2 ( COX-2 ) inhibitor with an IC 50 value of 18 nM, it also inhibits COX1- activity with an IC 50 value of 115 nM. Imrecoxib (BAP-909) has anti-inflammatory effect [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAP-909. CAS No. 395683-14-4. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-114200. | |
| IMS2186 | IMS2186 is an anti-choroidal neovascularization (CNV) agent that inhibits angiogenesis upstream of VEGF. IMS2186 can arrest cancer cell cycle in G2/M phase, thus exerting anti-proliferation and anti-angiogenesis effects. IMS2186 has no intraocular toxicity and reduces the amount of eye leakage and diseased cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1031206-36-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-101990. | |
| Imsidolimab | Imsidolimab (ANB 019) is a high-affinity, humanized monoclonal antibody of anti- IL-36R. Imsidolimab antagonizes IL-36 cytokine signal transduction. Imsidolimab has potential application in generalized pustular psoriasis (GPP) and other inflammatory skin diseases [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ANB 019. CAS No. 2102543-86-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99659. | |
| Inarigivir ammonium | Inarigivir (ORI-9020) ammonium is a dinucleotide antiviral drug that can significantly reduce liver HBV DNA in transgenic mice expressing hepatitis B virus. Inarigivir (ORI-9020) ammonium acts as a RIG-I (Retinoic acid-inducible gene-I) agonist to activate cellular innate immune responses [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ORI-9020 ammonium; SB-9000 ammonium. CAS No. 2172788-92-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-101954A. | |
| Inavolisib | Inavolisib (GDC-0077) is a potent, orally active, and selective PI3Kα inhibitor ( IC 50 =0.038 nM). Inavolisib exerts its activity by binding to the ATP binding site of PI3K, thereby inhibiting the phosphorylation of PIP2 to PIP3. Inavolisib is more selective for mutant versus wild-type PI3K&alpha. Inavolisib can be used for the study of breast cancer [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GDC-0077; RG6114. CAS No. 2060571-02-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101562. | |
| Inaxaplin | Inaxaplin (VX-147) is an orally active apolipoprotein L1 ( APOL1 ) function inhibitor (WO2020131807, compound 2). Inaxaplin can be used for the research of kidney disease [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: VX-147. CAS No. 2446816-88-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132820. | |
| Inbakicept | Inbakicept is a dimeric human IL-15 receptor alpha (IL-15 Ra) sushi domain/human IgG1 Fc fusion protein and is an IL-15 superagonist complex. Inbakicept is able to form complex N-803 (Nogapendekin alfa inbakicept) with the IL-15 antibody Nogapendekin alfa in a 1:2 ratio. N-803 mimics the function of IL-15 and amplifies anti-CD20 mAb-mediated NK cell responses and antibody-dependent cellular cytotoxicity (ADCC). N-803 also increases degranulation and IFNγ production in cells [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2135939-52-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99661. | |
| Incadronic acid | Incadronic acid inhibits growth of Dictyostelium discoideum with an IC 50 of 1.6 μM. Incadronic acid binds the farnesyl diphosphate synthase ( FPPS ) in Leishmania major with the K i of 23 nM. Incadronic acid inhibits the bone resorption and reduces bone loss, that can be used in osteoporosis research. Incadronic acid inhibits the proliferation of cells RAW264.7, PC-3 and MCF-7 with IC 50 of 48 to 228.6 μM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 124351-85-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-149149. | |
| INCB054329 | INCB054329 is a potent BET inhibitor. Uses: Scientific research. Group: Signaling pathways. CAS No. 1628607-64-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112504. | |
| INCB086550 | INCB086550 is a potent, oral, small-molecule PD-L1 inhibitor with IC 50s value of 3.1, 4.9 and 1.9 nM for human, cynomolgus, and rat, respectively. INCB086550 promotes the dimerization of cell-surface PD-L1 and induces PD-L1 entry into Golgi vesicles then traffick to the nucleus. INCB086550 can be used for multiple cancers research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PD-1/PD-L1-IN-8. CAS No. 2230911-59-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134884. | |
| Incensole | Incensole, a 14-membered diterpenoid, is isolated from both essential oils and resins of frankincense. Incensole has shown anti-inflammatory and anti-depression activities due to their ability to activate ion channels in the brain to alleviate anxiety or depression [1]. Uses: Scientific research. Group: Natural products. CAS No. 22419-74-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N4097. | |
| Incensole Acetate | Incensole acetate is a main constituent of Boswellia carterii resin , has neuroprotective effects against neuronal damage in traumatic and ischemic head injury. Incensole acetate reduces Aβ25 - 35-triggered apoptosis in hOBNSCs [1]. Uses: Scientific research. Group: Natural products. CAS No. 34701-53-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N4098. | |
| Inclacumab | Inclacumab (Anti-Human selectin P Recombinant Antibody) is a human monoclonal IgG4 antibody selectively targets P-selectin with a K d value of 9.9 nM. Inclacumab inhibits P-selectin glycoprotein ligand 1 (PSGL-1) mimetic peptide bind with P-selectin with an IC 50 value of 1.9 μg/mL and strongly inhibits cell adhesion [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-Human selectin P Recombinant Antibody. CAS No. 1256258-86-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99263. | |
| Incyclinide | Incyclinide (CMT-3, COL-3) is a matrix metalloproteinase ( MMP ) inhibitor and inhibiting angiogenesis, tumor growth and invasion, and metastasis. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CMT-3; COL-3. CAS No. 15866-90-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13648. | |
| Indacaterol | Indacaterol is an orally active ultra-long-acting β2 adrenergic receptor ( ADRB2 ) agonist. Indacaterol inhibits NF-κB activity in a β-arrestin2 -dependent manner, preventing further lung damage and improving lung function in COPD (chronic obstructive pulmonary disorder). Indacaterol can also be used in cardiovascular disease research [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 312753-06-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-14299. | |
| Indacaterol maleate | Indacaterol maleate (QAB149) is an orally active ultra-long-acting β2 adrenergic receptor ( ADRB2 ) agonist. Indacaterol maleate inhibits NF-κB activity in a β-arrestin2 -dependent manner, preventing further lung damage and improving lung function in COPD (chronic obstructive pulmonary disorder). Indacaterol maleate can also be used in cardiovascular disease research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: QAB149. CAS No. 753498-25-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-14299A. | |
| Indacaterol (maleate) (Standard) | Indacaterol (maleate) (Standard) is the analytical standard of Indacaterol (maleate). This product is intended for research and analytical applications. Indacaterol maleate (QAB149) is an orally active ultra-long-acting β2 adrenergic receptor ( ADRB2 ) agonist. Indacaterol maleate inhibits NF-κB activity in a β-arrestin2 -dependent manner, preventing further lung damage and improving lung function in COPD (chronic obstructive pulmonary disorder). Indacaterol maleate can also be used in cardiovascular disease research [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 753498-25-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14299AR. | |
| Indapamide | Indapamide is an orally active sulphonamide diuretic agent, that can reduce blood pressure by decreasing vascular reactivity and peripheral vascular resistance. Indapamide is also can reduce left ventricular hypertrophy [1] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 26807-65-8. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0259. | |
| Indatuximab | Indatuximab is a CHO-expressed, VHH-Fc (huIgG1) type chimeric antibody that targets Syndecan-1/CD138. The predicted molecular weight (MW) of Indatuximab is 146.1 kDa. The isotype control for Indatuximab can refer to Human IgG4 kappa, Isotype Control (HY-P99003). Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1238517-16-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990607. | |
| Indatuximab ravtansine | Indatuximab ravtansine (BT-062) is an antibody-drug conjugate (ADC) ( Antibody-Drug Conjugates (ADCs) ) based on a murine/human chimeric form of B-B4 (specific for CD138), linked to the maytansinoid agent DM4 by disulphide bonds. Indatuximab ravtansine shows anti-tumor activities [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BT-062; nBT062-DM4. CAS No. 1238517-16-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-141607. | |
| Indazole | Indazole, also called isoindazole, a heterocyclic aromatic organic compound. Its derivatives display a broad variety of biological activities including anti-inflammatory, antibacterial, anti-HIV, antiarrhythmic, antifungal and antitumour properties. Indazole and its derivatives can be used for research of cancer, neurological disorders, cardiovascular diseases, gastrointestinal diseases [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 271-44-3. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-40294. | |
| Indazole-3-carboxylic acid | Indazole-3-carboxylic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 4498-67-3. Pack Sizes: 25 g. Product ID: HY-W002518. | |
| Indeno[1,2,3-cd]pyrene | Indeno[1,2,3-cd]pyrene is a polycyclic aromatic hydrocarbon with moderate cytotoxicity in human pulmonary alveolar epithelial cells HPAEpiC. Indeno[1,2,3-cd]pyrene enhances allergic lung infammation via aryl hydrocarbon receptor [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 193-39-5. Pack Sizes: 1 mg (4.08 μg/mL * 1 mL in Methanol). Product ID: HY-23499. | |
| Indibulin | Indibulin (ZIO 301), an orally applicable inhibitor of tubulin assembly, shows potent anticancer activity with a minimal neurotoxicity. Indibulin reduces inter-kinetochoric tension, produces aberrant spindles, activates mitotic checkpoint proteins Mad2 and BubR1, and induces mitotic arrest and apoptosis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ZIO 301; D 24851. CAS No. 204205-90-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13649. | |
| Indican | Indican (Indoxyl-β-D-glucoside), a glycoside of indoxyl, is a precursor of the dyesindigo and indirubin. Indican has a major metabolite, indoxyl sulfate (IS). IS, an uremic toxin, is a substrate/inhibitor of organic anion transporter (OAT) 1, OAT 3 and multidrug resistance-associated protein (MRP) 4 [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Indoxyl-β-D-glucoside. CAS No. 487-60-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-122009. | |
| Indigo | Indigo is a deep and rich color dye for indole stain, isolated from the plant Indigofera tinctoria and related species [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 482-89-3. Pack Sizes: 100 mg; 1 g. Product ID: HY-N0335. | |
| Indigo carmine | Indigo carmine is an efficient reagent for the determination of ozone by chemlluminescence (CL) [1]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Indigotindisulfonate sodium; C.I.Acid Blue 74. CAS No. 860-22-0. Pack Sizes: 500 mg. Product ID: HY-W040226. | |
| Indinavir | Indinavir (MK-639 free base) is an orally active and selective HIV-1 protease inhibitor with a K i of 0.54 nM for PR. Indinavir exhibits anticancer activity by inhibiting the activation of MMPs-2 hydrolysis, anti-angiogenesis and inducing apoptosis. Indinavir is also a SARS-CoV 3CL pro inhibitor [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-639 free base; L-735524 free base. CAS No. 150378-17-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-B0689. | |
| Indinavir sulfate | Indinavir sulfate (MK-639) is an orally active and selective HIV-1 protease inhibitor with a K i of 0.54 nM for PR. Indinavir sulfate exhibits anticancer activity by inhibiting the activation of MMPs-2 hydrolysis, anti-angiogenesis and inducing apoptosis. Indinavir sulfate is also a SARS-CoV 3CL pro inhibitor [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-639; L735524. CAS No. 157810-81-6. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B0689A. | |
| Indirubin | Indirubin (Couroupitine B) is a bis-indole alkaloid and has emarkable anticancer activity against chronic myelocytic leukemia [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Couroupitine B; Indigo red; Indigopurpurin. CAS No. 479-41-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-N0117. | |
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