MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
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H-Ile-Trp-OH
H-Ile-Trp-OH (Ile-Trp), a dipeptide, is an angiotensin-converting enzyme (ACE) inhibitor with an IC 50 of 0.7 μM. H-Ile-Trp-OH inhibits predominantly the C-domain of ACE [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ile-Trp. CAS No. 13589-06-5. Pack Sizes: 10 mM * 1 mL; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-105858.
Hinokinin
Hinokinin (Compound 1) is a compound isolated from the stems of Hypoestes aristate. Hinokinin exhibits moderate activity of HIV-1 protease enzyme [1]. Uses: Scientific research. Group: Natural products. Alternative Names: (-)-Hinokinin. CAS No. 26543-89-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N10420.
Hinokitiol
Hinokitiol is a component of essential oils isolated from Chymacyparis obtusa , reduces Nrf2 expression, and decreases DNMT1 and UHRF1 mRNA and protein expression, with anti-infective, anti-oxidative, and anti-tumor activities. Uses: Scientific research. Group: Natural products. Alternative Names: β-Thujaplicin. CAS No. 499-44-5. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B2230.
HIPP
HIPP (α -(Hydroxyimino)benzenepropanoic acid) is an inhibitor for human C-terminal binding protein ( CtBP ), with IC 50 of 745 nM and a K d of 1.3 μM [1]. Uses: Scientific research. Group: Natural products. Alternative Names: α-(Hydroxyimino)benzenepropanoic acid. CAS No. 3682-17-5. Pack Sizes: 25 mg; 50 mg. Product ID: HY-121687.
Hippuric acid
Hippuric Acid is an orally active metabolite. Hippuric Acid can be produced by intestinal microorganisms from the metabolism of polyphenols, benzoic acid. Hippuric Acid decreases NRF2 , MMP9 and leads to ROS accumulation. Hippuric Acid activates TGFβ/SMAD signaling. Hippuric Acid improves hyperuricemia and colitis. Hippuric Acid can also be used in cardiovascular disease research [1] [2] [3] [4]. [5] [6] [7] [8] [9]. Uses: Scientific research. Group: Natural products. Alternative Names: Benzoylglycine. CAS No. 495-69-2. Pack Sizes: 10 mM * 1 mL; 500 mg; 5 g. Product ID: HY-W016562.
Hippuric acid (Standard)
Hippuric acid (Standard) is the analytical standard of Hippuric acid. This product is intended for research and analytical applications. Hippuric Acid is an orally active metabolite. Hippuric Acid can be produced by intestinal microorganisms from the metabolism of polyphenols, benzoic acid. Hippuric Acid decreases NRF2 , MMP9 and leads to ROS accumulation. Hippuric Acid activates TGFβ/SMAD signaling. Hippuric Acid improves hyperuricemia and colitis. Hippuric Acid can also be used in cardiovascular disease research [1] [2] [3] [4]. [5] [6] [7] [8] [9]. Uses: Scientific research. Group: Natural products. CAS No. 495-69-2. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-W016562R.
Hippuryl-Arg
Hippuryl-Arg (Bz-Gly-Arg) is a substrate used for fluorescence detection and is commonly used in biochemical studies, especially in studying enzyme activity. The phenylalanine portion of Hippuryl-Arg is connected by an aromatic side chain, which allows it to be detected under ultraviolet light. Hippuryl-Arg is used to detect enzymes that recognize and cut peptide bonds containing arginine [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Bz-Gly-Arg. CAS No. 744-46-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-131618.
Hirsutine
Hirsutine, an indole alkaloid of Uncaria rhynchophylla , exhibits anti-cancer activity. Hirsutine induces apoptosis and is a potent Dengue virus inhibitor exhibiting low cytotoxicity [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 7729-23-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-N2193.
Hirudin
Hirudin is a thrombin inhibitor with blood anticoagulant property. Hirudin has potent anti-thrombotic, wound repair, anti-fibrosis, anti-tumor and anti-hyperuricemia effects. Hirudin also affects diabetic complications, cerebral hemorrhage, and others [1]. Uses: Scientific research. Group: Peptides. CAS No. 8001-27-2. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-P2813.
Hispidin
Hispidin, a PKC inhibitor and a phenolic compound can be found in Phellinus linteus , has been shown to possess strong anti-oxidant, anti-cancer, anti-diabetic, and anti-dementia properties [1] [2] [3] [4] [5] [6] [7]. Uses: Scientific research. Group: Natural products. CAS No. 555-55-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100618.
Hispidulin
Hispidulin is a natural flavone with a broad spectrum of biological activities. Hispidulin is a Pim-1 inhibitor with an IC 50 of 2.71 μM. Uses: Scientific research. Group: Natural products. Alternative Names: Dinatin. CAS No. 1447-88-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N1950.
Hispolon
Hispolon, a polyphenol, can be isolated from Phellinus linteus. Hispolon possesses anticancer, antidiabetic, antioxidant, antiviral, hepatoprotective, anti-diabetic, and anti-inflammatory activities [1]. Uses: Scientific research. Group: Natural products. CAS No. 173933-40-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-150521.
Histamine
Histamine is an organic nitrogen compound that participates in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter. Uses: Scientific research. Group: Natural products. Alternative Names: Ergamine. CAS No. 51-45-6. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B1204.
Histamine-α,α,β,β-d4 dihydrochloride
Histamine-α, α, β, β-d 4 (dihydrochloride) is the deuterium labeled Histamine. Histamine is an organic nitrogenous compound involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: Ergamine-α,α,β,β-d4 (dihydrochloride). CAS No. 344299-48-5. Pack Sizes: 5 mg. Product ID: HY-B1204S.
Histamine dihydrochloride
Histamine dihydrochloride is a reactive oxygen species ( ROS ) inhibitor. Histamine dihydrochloride can suppress ROS production and work together with IL-2 to activate T cells and NK cells, leading to immune activation in the tumor microenvironment, which consequently kills acute myeloid leukemia (AML) cells. Histamine dihydrochloride can cause a reduction in vaginal tetrazo reduction, increased epithelial growth, and heightened keratinization in mouse models of ovariectomy. Histamine dihydrochloride can be used in the research of acute myeloid leukemia, malignant melanoma, and renal cell carcinoma [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 56-92-8. Pack Sizes: 10 mM * 1 mL; 500 mg; 5 g. Product ID: HY-B0722.
Histamine H4 receptor antagonist-1
Histamine H4 receptor antagonist-1 is an antagonist of histamine H4 receptor extracted from patent WO2010108059A1 compound 60 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1246207-84-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145106.
Histamine phosphate
Histamine (phosphate) is a strong histamine receptor activator and vasodilator neuroagent, capable of activating nitric oxide synthase. Uses: Scientific research. Group: Natural products. Alternative Names: Histamine diphosphate. CAS No. 51-74-1. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-A0129.
Histatin-3 TFA
Histatin-3 TFA, a 32 amino acid peptide, possesses powerful antimicrobial properties. Histatin-3 TFA behaves as a substrate for proprotein convertase 1 (PC1), being cleaved by this endoprotease primarily at a site carboxy terminal to the single Arg25 residue (HRGYR decrease SN). Histatin-3 TFA is a moderately potent, reversible and competitive inhibitor of the furin-mediated cleavage of the pentapeptide pGlu-Arg-Thr-Lys-Arg-MCA fluorogenic substrate, with an estimated inhibition constant K i of 1.98 μM [1]. Uses: Scientific research. Group: Peptides. CAS No. 112844-49-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P5272.
Histone H1-derived Peptide
Histone H1-derived Peptide is a phosphopeptide and the peptide substrates containes a sequence in accordance with the optimal recognition motif for CDK, can be used to detecting CDK1-cyclinB1 enzyme activity [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 889112-06-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P2480.
Histrelin acetate
Histrelin acetate, a GnRH analogue, is a GnRH Receptor agonist. Histrelin acetate increases serum luteinising hormone (LH), follicle stimulating hormone (FSH) and testosterone levels. Histrelin acetate can be used in the research of prostate cancer, endometriosis [1] [2] [5]. Uses: Scientific research. Group: Peptides. CAS No. 220810-26-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0056A.
HIV-1 inhibitor-6
HIV-1 inhibitor-6 (compound 9), a diheteroarylamide-based compound, is a potent HIV-1 pre-mRNA alternative splicing inhibitor. HIV-1 inhibitor-6 blocks HIV replication. HIV-1 inhibitor-6 is active against wild-type HIV-1IIIB (subtype B, X4-tropic) and HIV-1 97USSN54 (subtype A, R5-tropic) with EC 50 s of 0.6 μM and 0.9 μM, respectively. HIV-1 inhibitor-6 inhibits HIV strains resistant to agents targeting HIV reverse transcriptase, protease, integrase, and coreceptor CCR5 with EC 50 s ranging from 0.9 to 1.5 μM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1821309-39-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134851.
HIV-1 integrase inhibitor
HIV-1 integrase inhibitor is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 544467-07-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13025.
HIV-IN-6
HIV-IN-6 is a HIV-1 viral replication inhibitor by targeting Src family kinases (SFK) that interact with Nef protein of the virus, such as Hck [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 301357-74-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-147314.
HJC0152
HJC0152 is a signal transducers and activators of transcription 3 ( STAT3 ) inhibitor. Uses: Scientific research. Group: Signaling pathways. CAS No. 1420290-99-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100602.
HKOH-1r
HKOH-1r is a highly sensitive green fluorescent probe for the specific detection of ·OH in living cells with a maximum excitation wavelength and emission wavelength of 500 nm and 520 nm, respectively [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 2138472-08-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-D1159.
HKPerox-2
HKPerox-2 is a highly sensitive green fluorescent probe for the specific detection of H 2 O 2 in living cells with a maximum excitation wavelength and emission wavelength of 520 nm and 543 nm, respectively [2]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 2245230-79-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-D1157.
HL1
HL1 is a ligand for tridentate Schiff bases and is a potential fluorescent probe for metal ions. HL1 exhibits photoluminescence at a weak and strong excitation wavelength of 415 nm [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 202828-10-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-164055.
H-Leu-Gly-OH
H-Leu-Gly-OH is a Glycine (HY-Y0966) derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 686-50-0. Pack Sizes: 1 g; 5 g; 10 g; 25 g; 100 g. Product ID: HY-W016075.
H-Leu-OMe.HCl
H-Leu-OMe.HCl is a leucine derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 7517-19-3. Pack Sizes: 500 g. Product ID: HY-W016427.
HLI373 dihydrochloride
HLI373 dihydrochloride is an efficacious Hdm2 inhibitor. HLI373 dihydrochloride inhibits the ubiquitin ligase activity of Hdm2. HLI373 dihydrochloride is effective in inducing apoptosis of several tumor cells that are sensitive to DNA-damaging agents [1]. Antimalarial activity [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1782531-99-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-108640A.
H-Lys(Z)-OH
H-Lys(Z)-OH is a lysine derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 1155-64-2. Pack Sizes: 100 g; 500 g. Product ID: HY-W007750.
H-Lys(Z)-OMe.HCl
H-Lys(Z)-OMe.HCl is a lysine derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 27894-50-4. Pack Sizes: 10 g; 25 g; 100 g. Product ID: HY-W008182.
HM03
HM03 is a potent and selective HSPA5 (Heat shock 70kDa protein 5, also known as Bip, Grp78) inhibitor. HM03 has anticancer activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 500565-15-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125974.
HMR 1556
HMR 1556, a chromanol derivative, is a potent I Ks blocker with IC 50 s of 10.5 nM and 34 nM in canine and guinea pig left ventricular myocytes, respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 223749-46-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106369.
HOAT
HOAT is a commonly used peptide bond forming agent that may become an impurity in drug synthesis, but is not mutagenic. HOAT can be used for peptide fragment polycondensation and can also inhibit the racemization of peptide polycondensation [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 39968-33-7. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-Z0275.
HODHBt
HODHBt (HOOBt) inhibits STAT5-SUMO interaction by blocking SUMOylation of phosphorylated STAT5. HODHBt enhances the magnitude of IL-15 signaling and significantly increases the natural killer (NK) cell cytotoxicity phenotype and function and the generation of cytokine-induced memory-like (CIML) natural killer (NK) cells. HODHBt can be used for research of HIV-infection and cancer [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HOOBt. CAS No. 28230-32-2. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-Y0493.
HOE 33187
HOE 33187 is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 23623-08-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15563.
Hoechst 33258
Hoechst 33258 is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution [1]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: bisBenzimide H 33258; H 33258. CAS No. 23491-44-3. Pack Sizes: 50 mg; 100 mg. Product ID: HY-15558.
Hoechst 33258 analog
Hoechst 33258 analog is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 258843-62-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15623.
Hoechst 33342
Hoechst 33342 is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution [1]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: bisBenzimide H 33342; HOE 33342. CAS No. 23491-52-3. Pack Sizes: 50 mg; 100 mg. Product ID: HY-15559.
Hoechst 33342 analog
Hoechst 33342 analog is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 178481-68-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-15627.
HOE-S 785026
HOE-S 785026 is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution [1]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: meta-Hoechst. CAS No. 132869-83-1. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-15561.
Holo-Bovine Transferrin
Holo-Bovine Transferrin, a blood-plasma glycoprotein, is a target ligand for transferrin receptor. Holo-Bovine Transferrin can bind to and mediate the transport of iron [1] [2] [3]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 11096-37-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P3267.
Homatropine Bromide
Homatropine Bromide is an orally active muscarinic acetylcholine receptor antagonist and can be used as an anticholinergic agent [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 51-56-9. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0547A.
Homatropine methylbromide
Homatropine methylbromide (Homatropine methobromide) is muscarinic AChR antagonist, inhibits endothelial and smooth muscle muscarinic receptors of WKY-E and SHR-E with IC 50 of 162. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Homatropine methobromide. CAS No. 80-49-9. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-B1388.
Homoeriodictyol
Homoeriodictyol is a flavonoid metabolite of Eriocitrin in plasma and urine. Eriocitrin is a strong antioxidant agent [1]. Uses: Scientific research. Group: Natural products. CAS No. 446-71-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N8210.
Homogentisic acid
Homogentisic acid is a specific metabolite in urine and serum, which is used for diagnosis of alkaptonuria. Uses: Scientific research. Group: Natural products. CAS No. 451-13-8. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-113283.
Homogentisic acid (Standard)
Homogentisic acid (Standard) is the analytical standard of Homogentisic acid. This product is intended for research and analytical applications. Homogentisic acid is a specific metabolite in urine and serum, which is used for diagnosis of alkaptonuria. Uses: Scientific research. Group: Natural products. CAS No. 451-13-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113283R.
Homoharringtonine
Homoharringtonine (Omacetaxine mepesuccinate;HHT) is a cytotoxic alkaloid with antitumor properties which acts by inhibiting translation elongation. Uses: Scientific research. Group: Natural products. Alternative Names: Omacetaxine mepesuccinate; HHT. CAS No. 26833-87-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-14944.
Homologous recombination-IN-1
Homologous recombination-IN-1 is a novel RAD51-BRCA2 protein-protein interaction inhibitor ( EC 50 =19 μM). Homologous recombination-IN-1 can interfere with homologous recombination [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 391889-85-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148183.
Homopropargylglycine
Homopropargylglycine is a Methionine (HY-13694) analogue. Homopropargylglycine is incorporated at a suitable rate into newly synthesized proteins in a variety of systems, including mammalian cell culture. Homopropargylglycine can be used to identify old and new protein populations [1]. Homopropargylglycine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 215160-72-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-W259668.
Homosalate
Homosalate (Homomenthyl salicylate) is an organic compound used as a sunscreen to filter UV rays and protect the skin from sun damage. Homosalate has anti-inflammatory activity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Homomenthyl salicylate. CAS No. 118-56-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B0928.
Homovanillic acid
Homovanillic acid is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency. Uses: Scientific research. Group: Natural products. Alternative Names: Vanilacetic acid. CAS No. 306-08-1. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg. Product ID: HY-N0384.
Homovanillic acid (Standard)
Homovanillic acid (Standard) is the analytical standard of Homovanillic acid. This product is intended for research and analytical applications. Homovanillic acid is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency. Uses: Scientific research. Group: Natural products. Alternative Names: Vanilacetic acid (Standard). CAS No. 306-08-1. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0384R.
Honokiol
Honokiol is a bioactive, biphenolic phytochemical that possesses potent antioxidative, anti-inflammatory, antiangiogenic, and anticancer activities by targeting a variety of signaling molecules. It inhibits the activation of Akt. Honokiol can readily cross the blood brain barrier [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: NSC 293100. CAS No. 35354-74-6. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg. Product ID: HY-N0003.
Hordenine
Hordenine, an alkaloid found in plants, inhibits melanogenesis by suppression of cyclic adenosine monophosphate (cAMP) production [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Ordenina; Peyocactine. CAS No. 539-15-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 20 mg. Product ID: HY-N0113.
Hordenine hydrochloride
Hordenine (hydrochloride), an alkaloid found in plants, inhibits melanogenesis by suppression of cyclic adenosine monophosphate (cAMP) production [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Ordenina hydrochloride; Peyocactine hydrochloride. CAS No. 6027-23-2. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-N0113B.
HP210
HP210 is a selective glucocorticoid receptor modulator ( SGRM ). HP210 can inhibit the mRNA expression of IL-1β and IL-6. HP210 has the potential to study inflammation-related diseases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 728039-52-9. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-146564A.
HP-β-CD
HP-β-CD ((2-Hydroxypropyl)-β-cyclodextrin) is a widely used drug delivery vehicle to improve the stability and bioavailability. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: (2-Hydroxypropyl)-β-cyclodextrin. CAS No. 128446-35-5. Pack Sizes: 500 mg; 1 g; 5 g; 10 g. Product ID: HY-101103.
H-Phe(2-Me)-OH
H-Phe(2-Me)-OH is a phenylalanine derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 80126-53-0. Pack Sizes: 10 g; 25 g. Product ID: HY-W016555.
HPi1
HPi1 is a potent, selective and orally active antimicrobial against Helicobacter pylori with an IC 50 of 0.24 μM and an MIC of 0.08-0.16 μg/mL. HPi1 is inactive against other bacteria, including the gut commensals Lactobacillus casei , Lactobacillus reuteri , and Bifidobacterium longum [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 13080-21-2. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-120536.
HPMC
HPMC (Hypromellose) is a hydrophilic, non-ionic cellulose ether used to form swellable-soluble matrices. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Hypromellose; (Hydroxypropyl)methyl cellulose; Celacol HPM 5000. CAS No. 9004-65-3. Pack Sizes: 500 mg; 1 g. Product ID: HY-A0104.
HPPD-IN-3
HPPD-IN-3 (compound 25) is a potent inhibitor of 4-Hydroxyphenylpyruvate dioxygenase ( HPPD ), with IC 50 of 10 nM, more potency than Mesotrione (HY-12853) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3024245-46-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-161308.
HPPE
HPPE (compound 236) is an orally active, potential Bach1 inhibitor. Bach1 is a transcription factor of the cap'n'collar type alkaline region leucine zipper factor family (CNC-bZip) that regulates mitochondrial metabolism and reduces glucose utilization. HPPE can be used for research in psoriasis, multiple sclerosis, and COPD [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Bach1-IN-1. CAS No. 1325721-55-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-153040.
H-Pro-Hyp-OH
H-Pro-Hyp-OH is a collagen peptide composed of proline (Pro) and hydroxyproline (Hyp). H-Pro-Hyp-OH can be used in research on slowing down facial aging [1]. Uses: Scientific research. Group: Peptides. CAS No. 18684-24-7. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W337672.
HQ461
HQ461 is a molecular glue that promotes CDK12-DDB1 interaction to trigger cyclin K degradation. HQ461-mediated degradation of cyclin K impairs CDK12 function, resulting in decreased CDK12 substrate phosphorylation, downregulation of DNA damage response genes, and cell death [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1226443-41-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144981.
HRO761
HRO761 (Werner syndrome RecQ helicase-IN-1) (example 42) is a potent Werner syndrome RecQ DNA helicase enzyme ( WRN ) inhibitor and can be used in cancer research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Werner syndrome RecQ helicase-IN-1. CAS No. 2869954-34-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg. Product ID: HY-148699.
HRS-4642
HRS-4642 is a selective KRAS(G12D) inhibitor (Kd=0.083 nM) with anti-cancer activity. HRS-4642 synergizes with Carfilzomib (HY-10455) and exhibits significant in vivo potency to reshape the tumor microenvironment into an immune-activating microenvironment. Uses: Scientific research. Group: Signaling pathways. CAS No. 2836263-09-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-159127.
HS148
HS148 (compound 22) is a selective DAPK3 inhibitor with an K i value of 119 nM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1892595-16-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117364.
HS-27
HS-27, a fluorescently-tethered Hsp90 inhibitor, assays surface Hsp90 expression on intact tissue specimens. HS-27 is made up of the core elements of SNX-5422, an Hsp90 inhibitor, tethered via a PEG linker to a fluorescein derivative (fluorescein isothiocyanate or FITC), that binds to ectopically expressed Hsp90. HS-27 has potential use in a see-and-treat paradigm in breast cancer [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1562024-11-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130851.