MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Fasoracetam | Fasoracetam (NS 105) is the activator of metabotropic glutamate receptor ( mGluR ). Fasoracetam (NS 105) has the potential for the research of attention-deficit hyperactivity disorder (ADHD) and Alzheimer's disease (AD) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NS 105. CAS No. 110958-19-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107481. |  |
| Fast blue bb salt | Fast blue bb salt is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 5486-84-0. Pack Sizes: 1 g; 5 g. Product ID: HY-W250150. | |
| Fast Blue B Salt, Dye content ~95% | Fast Blue B Salt, Dye content ~95% is a coloring agent that dissolves fats and phenolic compounds extracted from rye, as well as diazonium. Fast Blue B Salt, Dye content ~95% can be used for the semiquantification of alkylresorcinols in rye and produces a color precipitate in the presence of acetone[1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 14263-94-6. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-W127711. | |
| Fast Blue RR Salt | Fast Blue RR Salt is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 55663-99-5. Pack Sizes: 1 g. Product ID: HY-W127771. | |
| Fast Green FCF | Fast Green FCF is a sea green triarylmethane food dye, with absorption maximum ranging from 622 to 626 nm. Fast Green FCF inhibits α-synuclein aggregation , as well as Aβ and P2X4 receptor, and TLR4/Myd88/NF-κB. Fast Green FCF is widely used as a staining agent like quantitative stain for histones at alkaline pH after acid extraction of DNA, and as a protein stain in electrophoresis. Fast Green FCF improves cognitive impairment, depression, relieves pain allergies, and promotes reproductive function [1] [2] [3] [4] [5] [6] [7] [8] [9]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: FD&C Green No. 3; Food green 3; C.I. 42053. CAS No. 2353-45-9. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-D0914. | |
| Fast Red Violet LB Zinc chloride | Fast Red Violet LB Zinc chloride is a stain that stains tartrate-resistant acid phosphatase (TRAP) and Fast Red Violet LB Zinc chloride can be used to stain alkaline phosphatase (ALP) activity[1][2]. Uses: Scientific research. Group: Fluorescent dye. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-D1491A. | |
| Fasudil Hydrochloride | Fasudil (HA-1077; AT877) Hydrochloride is a nonspecific RhoA/ROCK inhibitor and also has inhibitory effect on protein kinases, with an K i of 0.33 μM for ROCK1 , IC 50 s of 0.158 μM and 4.58 μM, 12.30 μM, 1.650 μM for ROCK2 and PKA , PKC , PKG , respectively. Fasudil Hydrochloride is also a potent Ca 2+ channel antagonist and vasodilator [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HA-1077 Hydrochloride; AT-877 Hydrochloride. CAS No. 105628-07-7. Pack Sizes: 10 mM * 1 mL; 200 mg; 500 mg. Product ID: HY-10341. | |
| Fatostatin | Fatostatin (125B11), a specific inhibitor of SREBP activation, impairs the activation of SREBP-1 and SREBP-2. Fatostatin binds to SCAP (SREBP cleavage-activating protein), and inhibits the ER-Golgi translocation of SREBPs. Fatostatin decreases the transcription of lipogenic genes in cells. Fatostatin possesses antitumor properties, and lowers hyperglycemia in ob/ob mice[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 125B11. CAS No. 125256-00-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14452. | |
| Fatostatin hydrobromide | Fatostatin hydrobromide (125B11 hydrobromide), a specific inhibitor of SREBP activation, impairs the activation of SREBP-1 and SREBP-2. Fatostatin hydrobromide binds to SCAP (SREBP cleavage-activating protein), and inhibits the ER-Golgi translocation of SREBPs. Fatostatin hydrobromide decreases the transcription of lipogenic genes in cells. Fatostatin hydrobromide possesses antitumor properties, and lowers hyperglycemia in ob/ob mice[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 125B11 hydrobromide. CAS No. 298197-04-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14452A. | |
| FAUC 213 | FAUC 213 is an orally active and highly selective dopamine D 4 receptor complete antagonist with a K i of 2.2 nM for hD 4.4. FAUC 213 has less activity on D 2 and D 3 receptors (K i s of 3.4 μM, 5.3 μM for hD 2 , hD 3 , respectively). FAUC 213 can cross the blood-brain barrier (BBB). FAUC 213 exhibits atypical antipsychotic characteristic [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 337972-47-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14327. | |
| FAUC 346 | FAUC 346, a highly selective D 3 partial agonist (EC 50 = 1.5 nM) [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 474432-65-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138809. | |
| FAUC 365 | FAUC 365 is a highly dopamine D3 receptor -selective antagonist with K i values of 0.5 nM, 340, 2600, and 3600 nM at D3, D4.4, D2 short , and D2 Long receptors, respectively. FAUC 365 can be used for the research of schizophrenia, and Parkinson's disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 474432-66-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116020. | |
| Favezelimab | Favezelimab (MK-4280) is a humanized anti-LAG-3 monoclonal antibody that blocks the interaction between LAG-3 and its ligand MHC class II. Favezelimab has the potential for colorectal cancer (CRC) research combined with the PD-L1 inhibitor Pembrolizumab (HY-P9902) [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MK-4280. CAS No. 2231068-83-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99613. | |
| Favipiravir | Favipiravir (T-705) is a potent viral RNA polymerase inhibitor, it is phosphoribosylated by cellular enzymes to its active form, Favipiravir-ribofuranosyl-5-triphosphate (RTP). Favipiravir-RTP inhibits the influenza viral RNA-dependent RNA polymerase ( RdRP ) activity with an IC 50 of 341 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: T-705. CAS No. 259793-96-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14768. | |
| FaX-IN-1 | FaX-IN-1 (compound 11A) is an intermediate in the preparation of FaX inhibitors and was used to study the inhibitory activity against venous thrombosis in rats [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 503614-91-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-75680. | |
| FAZ-3532 | FAZ-3532 is a G3BP inhibitor (Kd = 0.54 ?M) which binds to the NTF2L nsP3 binding pocket in G3BP1. FAZ-3532 disrupts the co-condensation of RNA, G3BP1, and caprin 1. FAZ-3532 inhibits G3BP-driven stress granule formation. FAZ-3532 can be studied as a powerful tool to probe the biology of stress granules and a promising interventions designed to modulate stress granule formation[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3036029-72-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-162288. | |
| FAZ-3780 | FAZ-3780 (compound G3Ib) is an inhibitor of binding to the NTF2L domain of G3BP1/2 that binds to G3BP1 with a Kd of 0.15 ?M. FAZ-3780 targets the protein-protein interaction domain of G3BP1/2 and specifically inhibits co-condensation of G3BP1, caprin 1, and RNA in vitro[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3036029-78-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-162289. | |
| Fazpilodemab | Fazpilodemab (BFKB8488A) is a humanized bispecific IgG1 antibody that selectively targets and activates fibroblast growth factor receptor 1c (FGFR1c) and Klotho?. Fazpilodemab can be used for the research of type 2 diabetes mellitus (T2DM) or nonalcoholic fatty liver disease (NAFLD)[1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BFKB8488A; RG-7992; RO-7040551. CAS No. 2517935-02-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99614. | |
| FB23-2 | FB23-2 is a potent and selective inhibitor of mRNA N6-methyladenosine (m6A) demethylase FTO, with an IC50 of 2.6 ?M. FB23-2 has anti-proliferation activity. FB23-2 can be used for the research of acute myeloid leukemia (AML)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2243736-45-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-127103. | |
| FBPase-IN-1 | FBPase-IN-1 is a potent FBPase (Fructose-1,6-bisphosphatase) inhibitor for Type 2 diabetes (T2D) study with an IC 50 of 0.22 μM. FBPase-IN-1 can reduce blood glucose levels and ameliorate glucose tolerance. FBPase-IN-1 modifies the C128 site, regulates the N125-S124-S123 allosteric pathway of FBPase and affects the catalytic activity of FBPase [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 20362-54-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-146725. | |
| FC-11 | FC-11 is a PROTAC FAK degrader ( DC 90 : 1 nM). FC-11 contains CRBN ligand Pomalidomide (HY-10984), linker and FAK ligand PF562271 (HY-10459) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2271035-37-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139344. | |
| FC-116 | FC-11 is a Tubulin inhibitor that effectively inhibits tumor growth in mice. FC-11 can also induce endoplasmic reticulum (ER) stress to generate excess reactive oxygen species (ROS), leading to mitochondrial damage, thereby promoting apoptosis in colorectal cancer (CRC) cells by targeting microtubules. FC-11 can be used in cancer research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2417298-29-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-155068. | |
| FC131 TFA | FC131 TFA is a CXCR4 antagonist, inhibits [ 125 I]-SDF-1 binding to CXCR4, with an IC 50 of 4.5 nM. Anti- HIV activity [1]. Uses: Scientific research. Group: Peptides. CAS No. 842166-42-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1104A. | |
| FCCP | FCCP is an uncoupler of oxidative phosphorylation ( OXPHOS ) in mitochondria. FCCP induces activation of PINK1 leading to Parkin Ser65 phosphorylation [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone. CAS No. 370-86-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100410. | |
| FDI-6 | FDI-6 is an inhibitor of FOXM1. FDI-6 binds directly to FOXM1 protein, to displace FOXM1 from genomic targets in MCF-7 breast cancer cells, and induce concomitant transcriptional down-regulation. Uses: Scientific research. Group: Signaling pathways. CAS No. 313380-27-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112721. | |
| FDW028 | FDW028 a potent and highly selective FUT8 inhibitor. FUT8 exhibits potent anti-tumor activity by defucosylation and impelling lysosomal degradation of B7-H3 through the chaperone-mediated autophagy (CMA) pathway. FDW028 can be used for metastatic colorectal cancer (mCRC) research[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2768426-49-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-155747. | |
| Febantel | Febantel is an oral dewormer used to treat gastrointestinal nematodes in sheep, as well as roundworm and tapeworm infections in poultry and livestock, and it also inhibits the embryonic development of mouse hairworms and whipworm eggs [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 58306-30-2. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g; 10 g. Product ID: HY-17597. | |
| Febrifugine | Febrifugine is a quinazolinone alkaloid found in the roots and leaves of Dichroa febrifuga , with antimalarial activity [1]. Uses: Scientific research. Group: Natural products. CAS No. 24159-07-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N2384. | |
| Febrifugine dihydrochloride | Febrifugine dihydrochloride is a quinazolinone alkaloid found in the roots and leaves of Dichroa febrifuga , with antimalarial activity [1]. Uses: Scientific research. Group: Natural products. CAS No. 32434-42-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N2384A. | |
| Febuxostat | Febuxostat (TEI 6720) is a potent, selective and non-purine xanthine oxidase (XO) inhibitor with a K i value of 0.6 nM. Febuxostat has the potential for the research of hyperuricemia and gout [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TEI 6720; TMX 67. CAS No. 144060-53-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14268. | |
| Fedratinib | Fedratinib (TG-101348) is a potent, selective, ATP-competitive and orally active JAK2 inhibitor with IC 50 s of 3 nM for both JAK2 and JAK2V617F kinase. Fedratinib shows 35- and 334-fold selectivity over JAK1 and JAK3, respectively. Fedratinib induces cancer cell apoptosis and has the potential for myeloproliferative disorders research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TG-101348; SAR 302503. CAS No. 936091-26-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 100 mg; 200 mg; 500 mg; 1 g; 2 g; 5 g. Product ID: HY-10409. | |
| Fedratinib hydrochloride hydrate | Fedratinib hydrochloride hydrate (TG-101348 hydrochloride hydrate) is a potent, selective, ATP-competitive and orally active JAK2 inhibitor with IC 50 s of 3 nM for both JAK2 and JAK2V617F kinase. Fedratinib hydrochloride hydrate shows 35- and 334-fold selectivity over JAK1 and JAK3, respectively. Fedratinib hydrochloride hydrate induces cancer cell apoptosis and has the potential for myeloproliferative disorders research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TG-101348 hydrochloride hydrate; SAR 302503 hydrochloride hydrate. CAS No. 1374744-69-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 100 mg; 200 mg; 500 mg; 1 g; 2 g; 5 g. Product ID: HY-10409A. | |
| Feladilimab | Feladilimab (Anti-ICOS/CD278 Reference Antibody (feladilimab); GSK3359609) is humanized IgG4 anti-ICOS agonist monoclonal antibody. Feladilimab binds to ICOS-expressing T cells. Feladilimab has the potential for the research of cancer [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-ICOS/CD278 Reference Antibody (feladilimab); GSK3359609. CAS No. 2252518-85-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99363. | |
| Felbamate | Felbamate (W-554) is a potent nonsedative anticonvulsant whose clinical effect may be related to the inhibition of N-methyl-D-aspartate (NMDA). Uses: Scientific research. Group: Signaling pathways. Alternative Names: W-554; ADD-03055. CAS No. 25451-15-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-B0184. | |
| Felbinac | Felbinac is a metabolite of fenbufen, an orally active nonsteroidal anti-inflammatory agent and a cyclooxygenase ( COX ) inhibitor with an IC 50 of 865.68 nM for COX1 and 976 nM for COX2. Felbinac reduces the production of prostaglandins by inhibiting COX to relieve pain, reduce inflammation and reduce fever. Felbinac can inhibit CHIKV viral activity [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 4-Biphenylacetic acid. CAS No. 5728-52-9. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-B0641. | |
| Felcisetrag | Felcisetrag (TD-8954) is an orally active, potent and selective 5-HT 4 receptor agonist with gastrointestinal prokinetic properties. Felcisetrag has high affinity ( pK i =9.4) for human 5-HT 4(c) receptors. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TD-8954. CAS No. 916075-84-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-102057. | |
| Felezonexor | CBS9106 (SL-801) is a reversible oral CRM1 inhibitor with CRM1 degrading and antitumor activities. CBS9106, inhibits CRM1-dependent nuclear export, causing arrest of the cell cycle and inducing apoptosis in a time- and dose-dependent manner for a broad spectrum of cancer cells[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CBS9106; SL-801. CAS No. 1076235-04-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-108716. | |
| Felodipine | Felodipine, a dihydropyridine, is a potent, vasoselective calcium channel antagonist. Felodipine lowers blood pressure (BP) by selective action on vascular smooth muscle, especially in the resistance vessels. Felodipine, an anti-hypertensive agent, induces autophagy. Felodipine can cross the blood-brain barrier [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 72509-76-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0309. | |
| Felypressin | Felypressin (PLV-2) is a non-catecholamine vasoconstrictor and a vasopressin 1 agonist. Felypressin is widely used in dental procedures [1] [2]. Uses: Scientific research. Group: Peptides. Alternative Names: PLV-2. CAS No. 56-59-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-A0182. | |
| Felypressin acetate | Felypressin acetate (PLV-2 acetate) is a non-catecholamine vasoconstrictor and a vasopressin 1 agonist. Felypressin acetate is widely used in dental procedures [1] [2]. Uses: Scientific research. Group: Peptides. Alternative Names: PLV-2 acetate. CAS No. 914453-97-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0182A. | |
| Felzartamab | Felzartamab (MOR-202) is a human monoclonal antibody that targets CD38 and can be used in multiple myeloma research [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MOR-202. CAS No. 2197112-39-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99616. | |
| FEMA 4809 | FEMA 4809 is a TRPM8 receptor agonist ( EC 50 =0.2 nM) for use as a cooling agent. TRPM8 is the ion channel responsible for the cool perception [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1374760-95-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130074. | |
| FEN1-IN-1 | FEN1-IN-1 (compound 1) is a small molecule flap endonuclease 1 (FEN1) inhibitor with antitumor activity. FEN1-IN-1 binds to the active site of FEN1 and partly achieves inhibition by the co-ordination of Mg2+ ions. FEN1-IN-1 initiaties a DNA damage response and activates the ATM checkpoint signalling pathway, the phosphorylation of histone H2AX and the ubiquitination of FANCD2 in mammalian cells. FEN1-IN-1 is promising for research of cancers[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 824983-91-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-123834. | |
| FEN1-IN-5 | FEN1-IN-5 (compound 12A) is a potent inhibitor of Flap endonuclease-1 ( FEN1 , IC 50 =12 nM), involving in DNA repair [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 824983-93-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-153790. | |
| Fenamic acid | Fenamic acid (N-Phenylanthranilic acid, NPAA) is an orally active chloride channel blocker. Fenamic acid is the basic constituent of non-steroidal anti-inflammatory agents (NSAIA), and derives into mefenamic, tofenacin, flufenac acid and melofenac acid. Fenamic acid also acts as antibacterial and analgesic agent [1] - [6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: N-Phenylanthranilic acid. CAS No. 91-40-7. Pack Sizes: 10 mM * 1 mL; 50 mg. Product ID: HY-W040265. | |
| Fenazaquin | Fenazaquin (XDE-436; EL-436) is a quinazoline acaricide [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: XDE-436; EL-436. CAS No. 120928-09-8. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-117397. | |
| Fenbendazole | Fenbendazole is an orally active benzimidazole anthelmintic agent, with a broad antiparasitic range. Fenbendazole is a microtubule destabilizing agent and acts on helminthes primarily by binding to tubulin and disrupting the tubulin microtubule equilibrium. Fenbendazole stabilizes the transcriptional activator HIF-1&alpha. Fenbendazole possesses an efficient anti-proliferative activity and induces apoptosis. Fenbendazole causes cell-cycle arrest and mitotic cell death, and has antitumor activity in mice xenografted with wild-type p53 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 43210-67-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0413. | |
| Fenbendazole (Standard) | Fenbendazole (Standard) is the analytical standard of Fenbendazole. This product is intended for research and analytical applications. Fenbendazole is an orally active benzimidazole anthelmintic agent, with a broad antiparasitic range. Fenbendazole is a microtubule destabilizing agent and acts on helminthes primarily by binding to tubulin and disrupting the tubulin microtubule equilibrium. Fenbendazole stabilizes the transcriptional activator HIF-1&alpha. Fenbendazole possesses an efficient anti-proliferative activity and induces apoptosis. Fenbendazole causes cell-cycle arrest and mitotic cell death, and has antitumor activity in mice xenografted with wild-type p53 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 43210-67-9. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0413R. | |
| Fenbufen | Fenbufen (CL-82204) is an orally active non-steroidal anti-inflammatory drug (NSAID) , with analgetic and antipyretic effects. Fenbufen has potent activity in a variety of animal model, including carageenin edema, UV erythema and adjuvant arthritis. Fenbufen has inhibitory activities against COX-1 and COX-2 with IC 50 s of 3.9 μM and 8.1 μM, respectively. Fenbufen is a caspases (caspase-1, 3, 4, 5, 9) inhibitor [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CL-82204. CAS No. 36330-85-5. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B1138. | |
| Fenchone | Fenchone is a natural product [1]. Uses: Scientific research. Group: Natural products. CAS No. 1195-79-5. Pack Sizes: 100 mg. Product ID: HY-124215. | |
| (-)-Fenchone | (-)-Fenchone, a bicyclic monoterpene, is widely distributed in plants and found in essential oils from Foeniculum vulgare. (-)-Fenchone is oxidized to 6- endo -hydroxyfenchone, 6- exo -hydroxyfenchone and 10-hydroxyfenchone derivatives by CYP2A6 and CYP2B6 in human liver microsomes with CYP2A6 playing a more important role than CYP2B6 [1]. Uses: Scientific research. Group: Natural products. CAS No. 7787-20-4. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-N5132. | |
| (+)-Fenchone | (+)-Fenchone exists in fennel seed oil ( Foenicufum vulgare Mill.) and in the oil of Lavandula stoechas. Fenchone is used as a flavor in foods and in perfumery [1]. Uses: Scientific research. Group: Natural products. CAS No. 4695-62-9. Pack Sizes: 50 mg; 100 mg. Product ID: HY-W015580. | |
| Fenchyl alcohol | Fenchyl alcohol is a monoterpene alcohol that can be used as a fragrance. Fenchyl alcohol has antifungal activity and can inhibit the formation of biofilms and hyphae of Candida albicans. Fenchyl alcohol also has a strong inhibitory effect on the rumen microbial activity of sheep and deer [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 1632-73-1. Pack Sizes: 100 mg; 500 mg. Product ID: HY-N7107. | |
| Fenclofenac | Fenclofenac is an orally active anti-inflammatory agent with a low ulcerogenic effect. Fenclofenac also exhibits antipyretic and analgesic activities, with an oral LD 50 of 2280 mg/kg in rats. Fenclofenac can be utilized in inflammation research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Flenac; R 67408. CAS No. 34645-84-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114806. | |
| Fenclonine | Fenclonine is a selective and irreversible tryptophan hydroxylase inhibitor, which is a rate-limiting enzyme in the biosynthesis of serotonin. Fenclonine can be used in carcinoid syndrome research[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 4-Chloro-DL-phenylalanine; PCPA; CP-10188. CAS No. 7424-00-2. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-B1368. | |
| Fenclozic acid | Fenclonic acid is an orally active analgesic, antipyretic and anti-inflammatory agente [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ICI-54450; Acidum fenclozicum; Mialex. CAS No. 17969-20-9. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-101432. | |
| Fendiline hydrochloride | Fendiline hydrochloride is a nonselective calcium channel blocker. Uses: Scientific research. Group: Signaling pathways. CAS No. 13636-18-5. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B0984. | |
| Fenebrutinib | Fenebrutinib (GDC-0853) is a potent, selective, orally available, and noncovalent bruton's tyrosine kinase ( Btk ) inhibitor with K i s of 0.91 nM, 1.6, 1.3, 12.6, and 3.4 nM for WT Btk, and the C481S, C481R, T474I, T474M mutants. Fenebrutinib has the potential for rheumatoid arthritis and systemic lupus erythematosus research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GDC-0853. CAS No. 1434048-34-6. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19834. | |
| Fenhexamid | Fenhexamid, a botryticide, is a sterol biosynthesis inhibitor. Fenhexamid shows fungicide efficient against the plant pathogenic fungus Botryotinia fuckeliana ( Botrytis cinerea ) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KBR 2738. CAS No. 126833-17-8. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-118065. | |
| Fenitrothion | Fenitrothion, one of the most widely used organophosphorus pesticides, is a cholinesterase inhibiting insecticide/acaricid. Fenitrothion is widely used, as a broad-spectrum insecticide, on cotton crops, vegetables crops, fruit crops, and field crops especially paddy. Fenitrothion leads to accumulation of nitrophenols [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 122-14-5. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg. Product ID: HY-B1885. | |
| Fenobam | Fenobam is a selective and orally active mGluR5 antagonist ( IC 50 =84 nM) that can penetrate the blood-brain barrier. Fenobam shows the K d values of 54 nM and 31 nM on rat and human recombinant mGlu5 receptors, respectively. Fenobam has anxiolytic activity, inhibits self-administration behavior in mice, and induces apoptosis in cancer cells. Fenobam can be used for research on neurological diseases, cancer and drug addiction [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 57653-26-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-101478. | |
| Fenobucarb | Fenobucarb is a carbamate insecticide. Fenobucarb induces zebrafish developmental neurotoxicity through pathways involved in inflammation, oxidative stress, degeneration and apoptosis. Fenobucarb is a possible risk factor to cardiovascular and cerebrovascular systems in animals [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3766-81-2. Pack Sizes: 10 mM * 1 mL; 250 mg. Product ID: HY-B0835. | |
| Fenofibrate | Fenofibrate is a selective PPARα agonist with an EC 50 of 30 μM. Fenofibrate also inhibits human cytochrome P450 isoforms, with IC 50 s of 0.2, 0.7, 9.7, 4.8 and 142.1 μM for CYP2C19 , CYP2B6 , CYP2C9 , CYP2C8 , and CYP3A4 , respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 49562-28-9. Pack Sizes: 10 mM * 1 mL; 200 mg; 5 g; 10 g. Product ID: HY-17356. | |
| Fenofibrate (Standard) | Fenofibrate (Standard) is the analytical standard of Fenofibrate. This product is intended for research and analytical applications. Fenofibrate is a selective PPARα agonist with an EC 50 of 30 μM. Fenofibrate also inhibits human cytochrome P450 isoforms, with IC 50 s of 0.2, 0.7, 9.7, 4.8 and 142.1 μM for CYP2C19 , CYP2B6 , CYP2C9 , CYP2C8 , and CYP3A4 , respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 49562-28-9. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-17356R. | |
| Fenofibric acid | Fenofibric acid, an active metabolite of fenofibrate, is a PPAR activitor, with EC 50 s of 22.4 μM, 1.47 μM, and 1.06 μM for PPARα, PPARγ and PPARδ, respectively; Fenofibric acid also inhibits COX-2 enzyme activity, with an IC 50 of 48 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FNF acid. CAS No. 42017-89-0. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-B0760. | |
| Fenofibric acid (Standard) | Fenofibric acid (Standard) is the analytical standard of Fenofibric acid. This product is intended for research and analytical applications. Fenofibric acid, an active metabolite of fenofibrate, is a PPAR activitor, with EC 50 s of 22.4 μM, 1.47 μM, and 1.06 μM for PPARα, PPARγ and PPARδ, respectively; Fenofibric acid also inhibits COX-2 enzyme activity, with an IC 50 of 48 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FNF acid (Standard). CAS No. 42017-89-0. Pack Sizes: 100 mg; 250 mg; 500 mg. Product ID: HY-B0760R. | |
| Fenoldopam mesylate | Fenoldopam mesylate (SKF-82526) is a D 1 receptor agonist and a novel lysine-specific demethylase 1 (LSD1) inhibitor ( IC 50 =0.8974 μM). Fenoldopam mesylate shows anti-hypertensive effects, anti-cancer cell proliferation activity and can induce cells apoptosis [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Fenoldopam methanesulfonate; SKF-82526 mesylate. CAS No. 67227-57-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0735A. | |
| Fenoprofen | Fenoprofen (LILLY-53858) is a nonsteroidal anti-inflammatory agent (NSAID). Fenoprofen can be used to to relieve symptoms of arthritis (osteoarthritis and rheumatoid arthritis), such as inflammation, swelling, stiffness, and joint pain. Fenoprofen is an allosteric enhancer for melanocortin receptors. Fenoprofen also increases ERK1/2 activation [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LILLY-53858. CAS No. 29679-58-1. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B1456A. | |
| Fenoprofen Calcium hydrate | Fenoprofen Calcium hydrate is a nonsteroidal, anti-inflammatory antiarthritic agent. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Fenoprofen calcium salt dihydrate. CAS No. 71720-56-4. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0288B. | |
| Fenoterol | Fenoterol (Th-1165), a sympathomimetic agent, is a selective and orally active β2-adrenoceptor agonist. Fenoterol is an effective bronchodilator and can be used for bronchospasm associated with asthma, bronchitis and other obstructive airway diseases research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Th-1165; Phenoterol. CAS No. 13392-18-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-B0976. | |
Would you like to list your products on USA Chemical Suppliers?
Our database is helping our users find suppliers everyday.