MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Fibronectin | Fibronectin, a glycoprotein present in blood as well as in cells, is a biomarker of tissue injury. Fibronectin binds to membrane-spanning receptor proteins called integrins. Fibronectin also binds to other extracellular matrix proteins such as collagen, fibrin, and heparan sulfate proteoglycans [1]. Uses: Scientific research. Group: Natural products. CAS No. 86088-83-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P3160. |  |
| Ficain | Ficain is an enzyme extract composed of several proteases that can be isolated from Ficus hispida L. and the latex of fig ( Ficus carica ). Ficain has different specificities in different proportions during fruit ripening. Ficain is widely used in protein hydrolysis, food, production of bioactive peptides and antibody fragments [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ficin. CAS No. 9001-33-6. Pack Sizes: 1 g. Product ID: HY-P3028. | |
| Ficlatuzumab | Ficlatuzumab is a monoclonal antibody (McAb) targeting human hepatocyte growth factor ( HGF ). Ficlatuzumab blocks the activation of the HGF/c-Met signaling pathway, and inhibits c-Met receptor-mediated cancer cell proliferation, migration, and invasion [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1174900-84-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99196. | |
| Ficonalkib | Ficonalkib is a potent inhibitor of Anaplastic lymphoma kinase (ALK) , the tyrosine kinase receptor. Ficonalkib, can be used as an antineoplastic agent [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2233574-95-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-152845. | |
| FICZ | FICZ is a potent aryl hydrocarbon receptor (AhR) agonist with a Kd of 70 pM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 6-Formylindolo[3,2-b]carbazole. CAS No. 172922-91-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12451. | |
| Fidarestat | Fidarestat (SNK 860) is an inhibitor of aldose reductase , with IC 50 s of 26 nM, 33 μM, and 1.8 μM for aldose reductase, AKR1B10 and V301L AKR1B10, respectively; Fidarestat (SNK 860) has the potential to treat diabetic disease. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SNK 860. CAS No. 136087-85-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-105185. | |
| FIDAS-5 | FIDAS-5 is a potent and orally active methionine S-adenosyltransferase 2A (MAT2A) inhibitor with an IC50 of 2.1 ?M. FIDAS-5 effectively competes against S-adenosylmethionine (SAM) for MAT2A binding. FIDAS-5 has anticancer activities[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1391934-98-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136144. | |
| Fidaxomicin | Fidaxomicin (OPT-80), a macrocyclic antibiotic , is an orally active and potent RNA polymerase inhibitor. Fidaxomicin has a narrow spectrum of antibacterial activity and a good anti- Clostridium difficile activity (MIC 90 =0.12?μg/mL). Fidaxomicin can be used for Clostridium difficile infection (CDI) research [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: OPT-80; PAR-101. CAS No. 873857-62-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17580. | |
| Fidrisertib | ALK2-IN-1 is a activin receptor-like kinase-2 ( ALK2 ) inhibitor extracted from patent WO2017181117A1, Compound 876, has an IC 50 of <10 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BLU-782; IPN-60130; ALK2-IN-1. CAS No. 2141955-96-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-117887. | |
| Figitumumab | Figitumumab (CP-751871) is a potent and fully human monoclonal anti - insulin-like growth factor 1 receptor ( IGF1R ) antibody. Figitumumab prevents IGF1 from binding to IGF1R with an IC 50 of 1.8 nM [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: CP-751871. CAS No. 943453-46-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99197. | |
| FIIN-1 | FIIN-1 is a potent, irreversible, selective FGFR inhibitor. FIIN-1 binds to FGFR1/2/3/4 and Flt1/4 with Kds of 2.8/6.9/5.4/120 nM and 32/120 nM respectively. The biochemical IC50s of FIIN-1 are 9.2, 6.2, 11.9, and 189 nM against FGFR1/2/3/4, respectively[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FGFR irreversible inhibitor-1. CAS No. 1256152-35-8. Pack Sizes: 2 mg; 5 mg; 10 mg. Product ID: HY-15813. | |
| FIIN-2 | FIIN-2 is an irreversible inhibitor of FGFR with an IC50 of 3.1, 4.3, 27, and 45 nM for FGFR1, FGFR2, FGFR3 and FGFR4, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1633044-56-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-18602. | |
| Filanesib | Filanesib (ARRY-520) is a selective and noncompetitive kinesin spindle protein ( KSP ) inhibitor, with an IC 50 of 6 nM for human KSP. Filanesib induces cell death by apoptosis in vitro. Filanesib has potent anti-proliferative activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ARRY-520. CAS No. 885060-09-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15187. | |
| Filapixant | Filapixant is a purinoreceptor antagonist extracted from patent WO2016091776A1, example 348. Filapixant is the active reference substance of Eliapixant [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 1902607. CAS No. 1948232-63-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109173. | |
| Filgotinib | Filgotinib (GLPG0634) is a selective, orally available JAK1 inhibitor with anti-inflammatory and antiviral activities. Filgotinib can effectively inhibit the activities of JAK1 , JAK2 , JAK3 and TYK2 with IC 50 values of 10 nM, 28 nM, 810 nM and 116 nM, respectively. Filgotinib also inhibits HIV-1 driven gene transcription and reduces proliferation of HIV-1 infected cells. Filgotinib can be used in the study of rheumatoid arthritis and inflammatory bowel disease [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GLPG0634. CAS No. 1206161-97-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18300. | |
| Filgotinib maleate | Filgotinib maleate (GLPG0634 maleate) is a selective, orally available JAK1 inhibitor with anti-inflammatory and antiviral activities. Filgotinib maleate can effectively inhibit the activities of JAK1 , JAK2 , JAK3 and TYK2 with IC 50 values ??of 10 nM, 28 nM, 810 nM and 116 nM, respectively. Filgotinib maleate also inhibits HIV-1 driven gene transcription and reduces proliferation of HIV-1 infected cells. Filgotinib maleate can be used in the study of rheumatoid arthritis and inflammatory bowel disease [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GLPG0634 maleate. CAS No. 1802998-75-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18300A. | |
| Filipin complex | Filipin complex is a potent polyene macrolide antifungal antibiotic. Filipin complex inserts into membranes and sequester cholesterol into complexes and inhibits PRRSV entry. The Filipin complex consists of about 75.8% Filipin III (HY-N6718), 10.8% Filipin IV, 9.1% Filipin II, and 1.2% Filipin I (Ex/Em = 380/430 nm)[1][2][3]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 11078-21-0. Pack Sizes: 5 mg; 10 mg; 50 mg. Product ID: HY-N6716. | |
| Filipin III | Filipin III is the major component of Filipin, a 28-membered ring pentaene macrolide antifungal antibiotic produced by S. filipinensis , S. avermitilis and S. miharaensis. Filipin interacts with membrane sterols causing the alteration of membrane structure [1]. Uses: Scientific research. Group: Natural products. CAS No. 480-49-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N6718. | |
| Fimasartan | Fimasartan (BRA-657) is an orally effective angiotensin receptor AT1 non-peptide antagonist. Fimasartan has antihypertensive effects. Fimasartan improves neuroinflammation and brain injury mediated by NLRP3 inflammatome after intracerebral hemorrhage, and has neuroprotective effect. Fimasartan inhibits the expression of inducible nitric oxide synthase through the inactivation of NF-κB and activator protein-1 [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BR-A-657. CAS No. 247257-48-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0780. | |
| Fimepinostat | Fimepinostat (CUDC-907) potently inhibits class I PI3K s as well as classes I and II HDAC enzymes with an IC 50 of 19/54/39 nM and 1.7/5.0/1.8/2.8 nM for PI3Kα/PI3Kβ/PI3Kδ and HDAC1/HDAC2/HDAC3/HDAC10 , respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CUDC-907. CAS No. 1339928-25-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13522. | |
| FIN56 | FIN56 is a specific inducer of ferroptosis. FIN56 induces ferroptosis by inducing degradation of GPX4. FIN56 also binds to and activates squalene synthase[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1083162-61-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103087. | |
| Finafloxacin | Finafloxacin is a fluoroquinolone antimicrobial agent that exhibits optimum efficacy in slightly acidic environments. Uses: Scientific research. Group: Signaling pathways. CAS No. 209342-40-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13451. | |
| Finasteride | Finasteride (MK-906) is an orally active and competitive 5α-reductase inhibitor, with an IC 50 of 4.2 nM for type II 5α-reductase. Finasteride has approximately a 100-fold greater affinity for type II 5α-reductase enzyme than for the type I enzyme. Finasteride can be used for the research of benign prostatic hyperplasia (BPH) and androgenic alopecia [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-906. CAS No. 98319-26-7. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg. Product ID: HY-13635. | |
| Finerenone | Finerenone (BAY 94-8862) is a third-generation, selective, and orally available nonsteroidal mineralocorticoid receptor (MR) antagonist ( IC 50=18 nM). Finerenone displays excellent selectivity versus glucocorticoid receptor (GR), androgen receptor (AR), and progesterone receptor (>500-fold). Finerenone has the potential for cardiorenal diseases research, such as type 2 diabetes mellitus and chronic kidney disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 94-8862. CAS No. 1050477-31-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111372. | |
| Fingolimod | Fingolimod (FTY720 free base) is a sphingosine 1-phosphate ( S1P ) antagonist with an IC 50 of 0.033 nM in K562 and NK cells. Fingolimod also is a pak1 activator, a immunosuppressant [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FTY720 free base. CAS No. 162359-55-9. Pack Sizes: 100 mg; 200 mg; 500 mg; 1 g; 5 g. Product ID: HY-11063. | |
| Fingolimod-d4 | Fingolimod-d 4 is the deuterium labeled Fingolimod. Fingolimod (FTY720 free base) is a sphingosine 1-phosphate (S1P) antagonist with an IC50 of 0.033 nM in K562 and NK cells. Fingolimod also is a pak1 activator, a immunosuppressant[1]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: FTY720 free based-d4. CAS No. 1346747-38-3. Pack Sizes: 500 μg; 1 mg. Product ID: HY-11063S. | |
| Fingolimod-d4 hydrochloride | Fingolimod-d 4 (hydrochloride) is the deuterium labeled Fingolimod hydrochloride. Fingolimod hydrochloride (FTY720) is a sphingosine 1-phosphate (S1P) antagonist with an IC50 of 0.033 nM in K562 and NK cells. Fingolimod hydrochloride (FTY720) also is a pak1 activator, a immunosuppressant[1]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: FTY720-d4. CAS No. 1346604-90-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-11063S1. | |
| Fingolimod hydrochloride | Fingolimod (FTY720) hydrochloride is a sphingosine 1-phosphate ( S1P ) antagonist with IC 50 of 0.033 nM in K562 and NK cells. Fingolimod hydrochloride is also a pak1 activator and immunosuppressant [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FTY720. CAS No. 162359-56-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg; 1 g; 5 g. Product ID: HY-12005. | |
| Fingolimod phosphate | Fingolimod phosphate (FTY720 phosphate) is an orally active sphingosine 1-phosphate (S1P) receptor agonist. Fingolimod phosphate can promote the neuroprotective effects of microglia. Fingolimod phosphate can be used for the research of multiple sclerosis and neurologic diseases [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FTY720 phosphate. CAS No. 402615-91-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15381. | |
| Fingolimod (Standard) | Fingolimod (Standard) is the analytical standard of Fingolimod. This product is intended for research and analytical applications. Fingolimod (FTY720 free base) is a sphingosine 1-phosphate (S1P) antagonist with an IC 50 of 0.033 nM in K562 and NK cells. Fingolimod also is a pak1 activator, a immunosuppressant [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 162359-55-9. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-11063R. | |
| FINO2 | FINO2 is a potent ferroptosis inducer. FINO2 inhibits GPX4 activity. FINO2 is a stable oxidant that oxidizes ferrous iron and stable at varying pH levels. FINO2 causes widespread lipid peroxidation [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 869298-31-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-129457. | |
| FIPI | FIPI is a phospholipase D (PLD) inhibitor with an IC50 for PLD1 and PLD2 of about 25 nM. FIPI regulates cytoskeletal recombination, cell diffusion and chemotaxis. FIPI can be used in cancer research. In addition, FIPI can enhance the secretion and aggregation of platelet dense particles, inhibit thrombosis, reduce ischemic stroke infarct volume and improve nerve function[1][2][3][4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 5-Fluoro-2-indolyl deschlorohalopemide. CAS No. 939055-18-2. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12807. | |
| Fipronil | Fipronil is a broad-spectrum insecticide effective against Lepidoptera species as well as thrips, locusts, ants, cockroaches, fleas and ticks. Fipronil selectively inhibits GABA receptor with IC 50 s of 30 nM and 1600 nM for cockroach and rat GABA receptors , respectively. Glutamate-gated chloride channels ( GluCls ), which are present in cockroaches but not in mammals, are sensitive to the blocking effect of Fipronil. Fipronil also induces apoptosis in HepG2 cells and promotes the expression of CYP1A1 and CYP3A4 mRNA in human hepatocytes [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 120068-37-3. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-B0822. | |
| Fipronil sulfone | Fipronil sulfone is the major metabolite of Fipronil.Fipronil sulfone selectively inhibits | |
| Firategrast | Firategrast (SB 683699) is an orally active and specific ?4?1/?4?7 integrin antagonist. Firategrast reduces trafficking of lymphocytes into the central nervous system (CNS) and decreases multiple sclerosis (MS) activity[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SB 683699. CAS No. 402567-16-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14951. | |
| Firefly luciferase-IN-1 | Firefly luciferase-IN-1 (compound 48) is a highly potent and reversible inhibitor of firefly luciferase with an IC50 value of 0.25 nM[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2765796-41-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-155945. | |
| Firibastat | Firibastat (QGC001), an orally active brain penetrating proagent of EC33, is a first-in-class brain aminopeptidase A (APA) inhibitor ( K i =200 nM). Firibastat selectively and specifically inhibits conversion of brain angiotensin-II into angiotensin-III and decreases blood pressure in hypertensive rats [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: QGC001; RB150. CAS No. 648927-86-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109058. | |
| Firmonertinib | Firmonertinib (Alflutinib; Furmonertinib) is an orally active, mutant-selective, and highly brain penetrant EGFR inhibitor. Firmonertinib inhibits EGFR active mutations as well as the T790M acquired resistant mutation. Firmonertinib has the potential for the research of cancer diseases, especially advanced non-small cell lung cancer (NSCLC) with EGFR ex20ins mutation [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Alflutinib; Furmonertinib; AST2818. CAS No. 1869057-83-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-112870. | |
| Firmonertinib mesylate | Firmonertinib (Alflutinib; Furmonertinib) mesylate is is an orally active, mutant-selective, and highly brain penetrant EGFR inhibitor. Firmonertinib mesylate inhibits EGFR active mutations as well as the T790M acquired resistant mutation. Firmonertinib mesylate has the potential for the research of cancer diseases, especially advanced non-small cell lung cancer (NSCLC) with EGFR ex20ins mutation [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Alflutinib mesylate; Furmonertinib mesylate; AST2818 mesylate. CAS No. 2130958-55-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112870A. | |
| Firocoxib | Firocoxib (ML 1785713) is a potent, selective and orally active COX-2 inhibitor with an IC 50 of 0.13 μM. Firocoxib shows 58-fold more selective for COX-2 than COX-1 (IC 50 of 7.5 μM). Firocoxib has anti-inflammatory effects [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ML 1785713. CAS No. 189954-96-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-14670. | |
| Firsocostat | Firsocostat (ND-630; GS-0976; NDI-010976) is an acetyl-CoA carboxylase ( ACC ) inhibitor; inhibits human ACC1 and ACC2 with IC 50 values of 2.1 and 6.1 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ND-630; GS-0976; NDI-010976. CAS No. 1434635-54-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16901. | |
| Fisetin | Fisetin is a natural flavonol found in many fruits and vegetables with various benefits, such as antioxidant, anticancer, neuroprotection effects. Uses: Scientific research. Group: Natural products. CAS No. 528-48-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-N0182. | |
| Fisetin (Standard) | Fisetin (Standard) is the analytical standard of Fisetin. This product is intended for research and analytical applications. Fisetin is a natural flavonol found in many fruits and vegetables with various benefits, such as antioxidant, anticancer, neuroprotection effects. Uses: Scientific research. Group: Natural products. CAS No. 528-48-3. Pack Sizes: 10 mg; 25 mg; 50 mg. Product ID: HY-N0182R. | |
| Fisogatinib | Fisogatinib (BLU-554) is a potent, highly selective and orally active fibroblast growth factor receptor 4 (FGFR4) inhibitor with an IC 50 of 5 nM. Fisogatinib has significant anti-tumor activity in models of hepatocellular carcinoma (HCC) that are dependent on FGFR4 signalling [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BLU-554. CAS No. 1707289-21-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100492. | |
| FITC | FITC (Fluorescein Isothiocyanate), is one of the green fluorescein derivatives widely used in biology. FITC has the characteristics of high absorptivity and excellent fluorescence quantum yield. The isothiocyanate group of FITC can be combined with amino, sulfhydryl, imidazole, tyrosyl, carbonyl and other groups on the protein, so as to achieve protein labeling including antibodies and lectins. In addition to its use as a protein marker, FITC can also be used as a fluorescent protein tracer to rapidly identify pathogens by labeling antibodies, or for microsequencing of proteins and peptides (HPLC). The maximum excitation wavelength of FITC is 494 nm. Once excited, it fluoresces yellow-green at a maximum emission wavelength of 520 nm. In addition, FITC is also a hapten that can induce contact hypersensitivity (CHS) and induce an atopic dermatitis model [1] [2] [3] [4]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Fluorescein 5-isothiocyanate. CAS No. 3326-32-7. Pack Sizes: 100 mg; 500 mg. Product ID: HY-66019. | |
| FITC-Dextran (MW 10000) | FITC-Dextran (MW 10000) is a fluorescent probe for fluorescein isothiocyanate (FITC) dextran (Ex=495 nm; Em=525 nm). FITC-Dextran (MW 10000) can be used as a marker to reveal heat shock-induced cell damage and to study the early and late stages of apoptosis. FITC-Dextran (MW 10000) can also be used for cell permeability studies, such as blood-brain barrier permeability and determination of the extent of blood-brain barrier disruption[1][2][3]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 60842-46-8. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-128868. | |
| FITC-Dextran (MW 150000) | FITC-Dextran (MW 150000) is a fluorescent probe for fluorescein isothiocyanate (FITC) dextran (Ex=491 nm; Em=518 nm). FITC-Dextran (MW 150000) can be used as a marker to reveal heat shock-induced cell damage and to study the early and late stages of apoptosis. FITC-Dextran (MW 150000) can be used in perfusion studies in animals or in fluorescence microlymphography, to study processes that affect the permeability of the blood brain barrier (BBB)[6]. FITC-Dextran (MW 150000) can be used as fluorescent probe to study cell permeability[7]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 60842-46-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128868G. | |
| FITC-Dextran (MW 20000) | FITC-Dextran (MW 20000) is a compound belonging to the class of fluorescent dyes. It is commonly used in biomedical research as a tracer molecule to label and track cells or other biological matter. FITC-Dextran consists of fluorescein isothiocyanate (FITC) and dextran, a complex carbohydrate derived from starch. The combination of the two creates a stable fluorescent tracer that can be viewed under a microscope or quantified using specialized detection instruments. Uses: Scientific research. Group: Fluorescent dye. CAS No. 60842-46-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128868C. | |
| FITC-Dextran (MW 2000000) | FITC-Dextran (MW 2000000) is a compound belonging to the class of fluorescent dyes. It is commonly used in biomedical research as a tracer molecule to label and track cells or other biological matter. FITC-Dextran consists of fluorescein isothiocyanate (FITC) and dextran, a complex carbohydrate derived from starch. The combination of the two creates a stable fluorescent tracer that can be viewed under a microscope or quantified using specialized detection instruments. Uses: Scientific research. Group: Fluorescent dye. CAS No. 60842-46-8. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-128868I. | |
| FITC-Dextran (MW 4000) | FITC-Dextran (MW 4000) is a fluorescent probe for fluorescein isothiocyanate (FITC) dextran (Ex=495 nm; Em=525 nm). FITC-Dextran (MW 4000) can be used as a marker to reveal heat shock-induced cell damage and to study the early and late stages of apoptosis. FITC-Dextran (MW 4000) can also be used for cell permeability studies, such as blood-brain barrier permeability and determination of the extent of blood-brain barrier disruption[1][2][3]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 60842-46-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-128868A. | |
| FITC-Dextran (MW 40000) | FITC-Dextran (MW 40000) is a fluorescent probe for fluorescein isothiocyanate (FITC) dextran (Ex=495 nm; Em=525 nm). FITC-Dextran (MW 40000) can be used as a marker to reveal heat shock-induced cell damage and to study the early and late stages of apoptosis. FITC-Dextran (MW 40000) can also be used for cell permeability studies, such as blood-brain barrier permeability and determination of the extent of blood-brain barrier disruption[1][2][3]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 60842-46-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128868D. | |
| FITC-Dextran (MW 500000) | FITC-Dextran (MW 500000) is a compound belonging to the class of fluorescent dyes. It is commonly used in biomedical research as a tracer molecule to label and track cells or other biological matter. FITC-Dextran consists of fluorescein isothiocyanate (FITC) and dextran, a complex carbohydrate derived from starch. The combination of the two creates a stable fluorescent tracer that can be viewed under a microscope or quantified using specialized detection instruments. Uses: Scientific research. Group: Fluorescent dye. CAS No. 60842-46-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128868H. | |
| FITC-Dextran (MW 70000) | FITC-Dextran (MW 70000) is a compound belonging to the class of fluorescent dyes. It is commonly used in biomedical research as a tracer molecule to label and track cells or other biological matter. FITC-Dextran consists of fluorescein isothiocyanate (FITC) and dextran, a complex carbohydrate derived from starch. The combination of the two creates a stable fluorescent tracer that can be viewed under a microscope or quantified using specialized detection instruments. Uses: Scientific research. Group: Fluorescent dye. CAS No. 60842-46-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-128868E. | |
| FITM | FITM is a negative allosteric modulator of mGlu1 receptor with a K i of 2.5 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 932737-65-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101845. | |
| FiVe1 | FiVe1 is a vimentin (VIM) inhibitor. FiVe1 binds to the rod domain of VIM, causing metaphase VIM disassembly and hyperphosphorylation at Ser56, ultimately leading to mitotic catastrophe, multinucleation, and loss of stemness. FiVe1 has anticancer activity against soft tissue sarcomas. FiVe1 increases the sensitivity of ovarian cancer to Cisplatin (HY-17394). FiVe1 can be used for researches of mesenchymal cancers (including breast cancer and soft tissue sarcoma) and ovarian cancers[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 932359-76-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124757. | |
| FKBP12 PROTAC dTAG-13 | FKBP12 PROTAC dTAG-13 (dTAG-13), a PROTAC-based heterobifunctional degrader, is a selective degrader of FKBP12F36V with expression of FKBP12F36V in-frame with a protein of interest. FKBP12 PROTAC dTAG-13 effectively engages FKBP12F36V and CRBN, thereby selectively degrading FKBP12F36V[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: dTAG-13. CAS No. 2064175-41-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-114421. | |
| FKBP12 PROTAC dTAG-7 | FKBP12 PROTAC dTAG-7 (dTAG-7) is a heterobifunctional PROTAC degrader. FKBP12 PROTAC dTAG-7 targets FKBP12F36V and BET BRD4. FKBP12 PROTAC dTAG-7 enables rapid and selective degradation of target proteins, and is suitable for cellular and in vivo studies to analyze protein functions and validate targets[1]. (Pink: target protein ligand (HY-114420); Black: linker (HY-128844); Blue: CRBN Ligand (HY-103597); CRBN Ligand+linker: (HY-W722323)). Uses: Scientific research. Group: Signaling pathways. Alternative Names: dTAG-7. CAS No. 2064175-32-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-123941. | |
| FL118 | FL118 (10,11-(Methylenedioxy)-20(S)-camptothecin), a Camptothecin (HY-16560) analogue, is a potent and orally active survivin inhibitor. FL118 binds to oncoprotein DDX5 (p68) to dephosphorylates and degrades DDX5. FL118 can be used for the research of cancer[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 10,11-(Methylenedioxy)-20(S)-camptothecin. CAS No. 135415-73-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12486. | |
| FL118-14-Propanol | FL118-14-Propanol is a FL118 derivative. FL118-14-Propanol synthesized ADC molecule has good anti-tumor effect in mice[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2821768-98-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-156856. | |
| FL-411 | FL-411 is a potent and selective BRD4 inhibitor with an IC 50 of 0.43±0.09 μM for BRD4(1). Uses: Scientific research. Group: Signaling pathways. Alternative Names: BRD4-IN-1. CAS No. 2118944-88-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111102. | |
| Flagelin 22 TFA | Flagelin 22 TFA (Flagellin 22 TFA), a fragment of bacterial flagellin, is an effective elicitor in both plants and algae[1][2][3]. Uses: Scientific research. Group: Peptides. Alternative Names: Flagellin 22 TFA. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1568A. | |
| FLAG peptide | FLAG peptide is a multifunctional fusion tag for the purification of recombinant proteins. FLAG peptide maintances the natural folding of its fusing proteins. FLAG peptide can be removed by enterokinase, and eluted under non-denaturing conditions [1]. Uses: Scientific research. Group: Peptides. CAS No. 98849-88-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P0223. | |
| FlAsH-EDT2 | FlAsH-EDT2 is a protein labeling reagent. FlAsH-EDT2 binds to Cys4 with high affinity and emits fluorescence. FlAsH-EDT2 can cross the cell membrane and enter the interior of the cell. FlAsH-EDT2 can only be used for labeling proteins with high concentration[1][2]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 212118-77-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-130412. | |
| Flavanone | Flavanone is a naturally occurring flavone. Flavanone has inhibitory activity for human estrogen synthetase ( aromatase ). Flavanone is the inhibitor for ERK/p38/NF-κB signaling pathway. Flavanone exhibits oral activity and antitumor efficacy [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 487-26-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-N7128. | |
| Flavin adenine dinucleotide | Flavin adenine dinucleotide (FAD) is a redox cofactor, more specifically a prosthetic group of a protein, involved in several important enzymatic reactions in metabolism. Uses: Scientific research. Group: Natural products. Alternative Names: FAD. CAS No. 146-14-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-B1654. | |
| Flavin adenine dinucleotide disodium salt | Flavin adenine dinucleotide (FAD) disodium salt is a redox cofactor, more specifically a prosthetic group of a protein, involved in several important enzymatic reactions in metabolism. Uses: Scientific research. Group: Natural products. Alternative Names: FAD disodium salt; FAD-Na2. CAS No. 84366-81-4. Pack Sizes: 10 mM * 1 mL; 25 mg. Product ID: HY-B1654A. | |
| Flaviviruses-IN-3 | Flaviviruses-IN-3 (compound 87) is a potent flaviviruse inhibitor. Flaviviruses-IN-3 reduces the WNV (West Nile virus) protease activity, with a inhibition of 54% [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 420090-97-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-153076. | |
| Flavokawain A | Flavokawain A, a proming anticarcinogenic agent , is a chalcone from kava extract with anti-tumor activity. Flavokawain A induces cell apoptosis by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway. Flavokawain A has the potential for the study of bladder cancer [1]. Uses: Scientific research. Group: Natural products. CAS No. 3420-72-2. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-N2420. | |
| Flavokawain B | Flavokawain B (Flavokavain B) is an orally active chalcone. Flavokawain B results in activation of caspase-9, -3 and -8 , cleavage of PARP. Flavokawain B down-regulates Bcl-2 with concomitant increase in Bax level. Flavokawain B inhibits NF-κB , PI3K/Akt and MAPK signaling pathway. Flavokawain B exhibits Apoptotic effects. Flavokawain B inhibits MMP-9 and promotes ROS generation. Flavokawain B inhibits multiple tumors and inflammation [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [11] [12] [13]. Uses: Scientific research. Group: Natural products. Alternative Names: Flavokavain B. CAS No. 1775-97-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N2132. | |
| Flavone | Flavone is an endogenous metabolite. Uses: Scientific research. Group: Natural products. Alternative Names: 2-Phenyl-4-chromone. CAS No. 525-82-6. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-N2424. | |
Would you like to list your products on USA Chemical Suppliers?
Our database is helping our users find suppliers everyday.