MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Intetumumab | Intetumumab (CNTO 95) is a potent anti- EGFR monoclonal antibody that is glycoengineered for enhanced antibody-dependent cellular cytotoxicity (ADCC). Intetumumab can be used in research of cancer [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: CNTO 95; Anti-Human CD51 Recombinant Antibody. CAS No. 725735-28-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99296. |  |
| Intralipid 20% | Intralipid 20% is a safe fat emulsion that can be used as a nutritional supplement. Intralipid 20% effectively inhibits the opening of the mitochondrial permeability transition pore, effectively protecting the heart from ischaemia-reperfusion injury and has some potential to modulate the innate immune response [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 68890-65-3. Pack Sizes: 100 mg. Product ID: HY-131370B. | |
| Inulin | Inulin is an orally active prebiotic targeting the intestinal microbiota, selectively promoting the proliferation and activity of beneficial bacteria such as bifidobacteria and lactic acid bacteria, and playing a role in regulating the intestinal microecology. The functions of Inulin include: ? Fermentation by probiotics in the colon to produce short-chain fatty acids (such as butyrate and propionate), lowering the intestinal pH and inhibiting the overgrowth of harmful bacteria; ? Enhancing the intestinal barrier function and reducing endotoxin translocation; ? Directly scavenging free radicals (such as superoxide free radicals, hydroxyl free radicals) and activating antioxidant enzymes (SOD, CAT) to reduce oxidative stress. Inulin can also be used in the study of intestinal diseases (constipation, IBD), metabolic syndrome (diabetes, obesity) and liver damage by regulating glucose and lipid metabolism (such as reducing triglycerides, improving insulin sensitivity) and immune response (enhancing NK cell activity, inhibiting inflammatory factors) [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 9005-80-5. Pack Sizes: 100 mg. Product ID: HY-N7075. | |
| Inulinase | Inulinase is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Signaling pathways. CAS No. 9025-67-6. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-P3261. | |
| Invertase, baker's yeast (S. cerevisiae) | Invertase, baker's yeast (S. cerevisiae) is a major enzyme present in plants and microorganisms, is often used in biochemical studies. Invertase catalyzes the hydrolysis of the disaccharide sucrose into glucose and fructose [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: β-D-Fructofuranosidase. CAS No. 9001-57-4. Pack Sizes: 250 mg; 500 mg; 1 g. Product ID: HY-P2979. | |
| Iobenguane sulfate | Iobenguane sulfate (MIBG sulfate) is an analogue of the neurotransmitter norepinephrine with antitumor activity. Radioiodinated Iobenguane sulfate is clinically used as a tumor-targeted radiopharmaceutical in the diagnosis and treatment of adrenergic tumors. Iobenguane sulfate is a high-affinity substrate for cholera toxin that interferes with cellular mono(ADP-ribosylation) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MIBG sulfate. CAS No. 87862-25-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129040A. | |
| Iodipamide | Iodipamide is a tri-iodinated benzoate derivative and ionic dimeric contrast agent used in diagnostic imaging. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Adipiodone. CAS No. 606-17-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-B1292. | |
| Iodixanol | Iodixanol is an iodine-containing non-ionic radiocontrast agent [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 92339-11-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1426. | |
| Iodobenzene | Iodobenzene (1-Iodobenzene) is a biological material or organic compound that can be used in life science research [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: 1-Iodobenzene. CAS No. 591-50-4. Pack Sizes: 10 mM * 1 mL; 25 g; 100 g. Product ID: HY-Y0747. | |
| Iohexol | Iohexol is a non-ionic, water-soluble contrast agent used as a reference marker for the determination of glomerular filtration rate (GFR) at the level of renal function. Iohexol can be used for contrast in myelography, computerized tomography (cisternography, ventriculography) and MicroCT imaging [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 66108-95-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0594. | |
| I-OMe-Tyrphostin AG 538 | I-OMe-Tyrphostin AG 538 (I-OMe-AG 538) is a specific inhibitor of IGF-1R (insulin-like growth factor-1 receptor tyrosine kinase). I-OMe-Tyrphostin AG 538 inhibits IGF-1R-mediated signaling and is preferentially cytotoxic to nutrient-deprived PANC1 cells. I-OMe-Tyrphostin AG 538 is an ATP-competitive inhibitor of phosphatidylinositol-5-phosphate 4-kinase α (PI5P4Kα) , with an IC 50 of 1 μM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: I-OMe-AG 538. CAS No. 1094048-77-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135680. | |
| Ionizable lipid-1 | Ionizable lipid-1 (compound II-10) is an ionizable lipid ( pKa =6.16) that can be used to prepare lipid nanoparticles (LNP) with bilayer structure [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 2055939-68-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156630. | |
| Ionomycin | Ionomycin (SQ23377) is a potent, selective calcium ionophore and an antibiotic produced by Streptomyces conglobatus. Ionomycin (SQ23377) is highly specific for divalent cations (Ca>Mg>Sr=Ba). Ionomycin (SQ23377) promotes apoptosis. Ionomycin also induces the activation of protein kinase C (PKC) [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: SQ23377. CAS No. 56092-81-0. Pack Sizes: 1 mg (14.1 mM * 100 μL in Ethanol); 5 mg (14.1 mM * 500 μL in Ethanol); 10 mg (14.1 mM * 1 mL in Ethanol). Product ID: HY-13434. | |
| Ionomycin calcium | Ionomycin calcium (SQ23377 calcium) is a potent, selective calcium ionophore and an antibiotic produced by Streptomyces conglobatus. Ionomycin calcium (SQ23377 calcium) is highly specific for divalent cations (Ca>Mg>Sr=Ba). Ionomycin (SQ23377) promotes apoptosis. Ionomycin calcium (SQ23377 calcium) also induces the activation of protein kinase C (PKC) [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: SQ23377 calcium. CAS No. 56092-82-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-13434A. | |
| Iopamidol | Iopamidol is a nonionic, X-Ray iodinated contrast agent (CA) for a wide variety of diagnostic applications. Iopamidol contains amide and hydroxyl functionalities that can be exploited for the generation of the chemical exchange saturation transfer (CEST) contrast [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: B-15000; SQ-13396. CAS No. 60166-93-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0684. | |
| Iopanoic acid | Iopanoic acid is an inhibitor of 5'-Deiodinase and also an iodinated contrast medium. Uses: Scientific research. Group: Signaling pathways. CAS No. 96-83-3. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B1664. | |
| Iopentol | Iopentol is a non-ionic, intravascular contrast media [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 89797-00-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-142121. | |
| Iopromide | Iopromide is a non-ionic, monomeric, iodine-based contrast medium for intravascular administration. Uses: Scientific research. Group: Signaling pathways. CAS No. 73334-07-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1362. | |
| Ι-Carrageenan | Ι-Carrageenan (Viscarin SD 309) is a biochemical reagent. Ι-Carrageenan can be isolated from Eucheuma serra or red algae H. musciformis and S. filiformis. Ι-Carrageenan has potential application in protein emulsion flocculation and stability [1] [2] [3] [4]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Viscarin SD 309. CAS No. 9062-7-1. Pack Sizes: 5 g. Product ID: HY-W145523. | |
| Iotalamic acid | Lotalamic acid (Iothalamic acid) is a contrast agent. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Iothalamic acid. CAS No. 2276-90-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-B1053. | |
| Ioversol | Ioversol (MP-328) is a nonionic iodinated contrast medium (CM) that is used during a CT scan or x-ray in animal experiment. Ioversol does not damage the blood-brain barrier (BBB) in animal [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MP-328. CAS No. 87771-40-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B1410. | |
| IOX2 | IOX2 is a specific prolyl hydroxylase-2 ( PHD2 ) inhibitor with IC 50 of 22 nM. IOX2 regulates platelet function and arterial thrombosis by upregulating HIF-1α expression and inhibiting ROS production. IOX2 can be used in the study of thrombotic diseases [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 931398-72-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15468. | |
| Ioxilan | Ioxilan is a low-osmolar, nonionic and tri-iodinated diagnostic contrast agent. Ioxilan is also an X-ray contrast agent for excretory urography and contrast enhanced computed tomographic (CECT) imaging of the head and body. Intravascular injection results in opacification of vessels in the path of flow of the contrast medium, permitting radiographic visualization of the internal structures of the human body until significant hemodilution occurs [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 107793-72-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-109513. | |
| IP6K2-IN-2 | IP6K2-IN-2 (Compound 6) is an IP6K2 inhibitor, with IC 50 values of 0.58 μM ( IP6K2 ), 0.86 μM ( IP6K1 ) and 3.08 μM ( IP6K3 ). IP6K2-IN-2 can be used in research of obesity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2967648-66-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-122706A. | |
| IPA-3 | IPA-3 is a selective non-ATP competitive PAK1 inhibitor with IC 50 of 2.5 μM, and shows no inhibition to group II PAKs (PAKs 4-6). Uses: Scientific research. Group: Signaling pathways. CAS No. 42521-82-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15663. | |
| IPAG | IPAG is a potent sigma-1 receptor antagonist with a pK i of 4.3 [1]. IPAG induces apoptosis [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 193527-91-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100985. | |
| Ipatasertib | Ipatasertib (GDC-0068) is an orally active, highly selective and ATP-competitive pan- Akt inhibitor with IC 50 values of 5, 18, 8 nM for Akt1/2/3 , respectively. Ipatasertib synchronously activates FoxO3a and NF-κB through inhibition of Akt leading to p53-independent activation of PUMA. Ipatasertib also induces apoptosis in cancer cells and inhibits tumor growth in xenograft mouse models [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GDC-0068; RG7440. CAS No. 1001264-89-6. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-15186. | |
| Ipatasertib dihydrochloride | Ipatasertib dihydrochloride (GDC-0068 dihydrochloride) is a highly selective and ATP-competitive pan-Akt inhibitor with IC 50 s of 5, 18 and 8 nM for Akt1 , Akt2 and Akt3 , respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GDC-0068 dihydrochloride; RG-7440 dihydrochloride. CAS No. 1396257-94-5. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-15186A. | |
| Ipflufenoquin | Ipflufenoquin is an insecticide with the potential to control primary infection with apple scab. Ipflufenoquin should be applied between half an inch of green and fruit set [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1314008-27-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-134338. | |
| Ipidacrine | Ipidacrine is orally active and brain-penetrant AChE and BuChE inhibitors with IC 50 values of 1 μM and 1.9 μM, respectively, which is also a partial agonist of M2-cholinergic receptors and a reversible cholinesterase inhibitor. Ipidacrine has a stimulating effect on neuromuscular transmission and excitation along the nerve fibres with a moderately anti-pain effect. Ipidacrine is an aminopyridines and is structurally similar to Tacrine (HY-111338). Ipidacrine is effective in various amnesia models, improves erectile function and inhibits K + and Na + -channels in the neuronal membrane in diabetic rats. Ipidacrine is promising for research of Alzheimers disease, ischaemic stroke, idiopathic neuropathy of the facial nerve, diabetes mellitus-induced erectile dysfunction and other deficits in central or peripheral cholinergic deseases [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NIK-247 free base. CAS No. 62732-44-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-W027553. | |
| Ipilimumab | Ipilimumab is a fully human monoclonal antibody IgG1κ that blocks the inhibitory receptor cytotoxic T lymphocyte antigen 4 ( CTLA-4 ) on T cells. Ipilimumab can be used in unresectable or metastatic melanoma (MM) studies [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MDX-010; BMS-734016. CAS No. 477202-00-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P9901. | |
| Ipragliflozin | Ipragliflozin (ASP1941) is an orally active and selective SGLT2 inhibitor with IC 50 s of 7.38 and 1876 nM, 6.73 and 1166 nM, 5.64 and 1380 nM for human SGLT2 and SGLT1, rat SGLT2 and SGLT1, mouse SGLT2 and SGLT1, respectively. Antidiabetic agent [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ASP1941. CAS No. 761423-87-4. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-14894. | |
| Ipratropium bromide | Ipratropium bromide (Sch 1000) is a muscarinic receptor antagonist, with IC 50 s of 2.9 nM, 2 nM, and 1.7 nM for M1, M2, and M3 receptors, respectively. Ipratropium bromide relaxes smooth muscle, can be used in the research for COPD (chronic obstructive pulmonary disease) and asthma [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Sch 1000. CAS No. 22254-24-6. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-B0241. | |
| Ipratropium bromide hydrate | Ipratropium bromide (Sch 1000) hydrate is a muscarinic receptor antagonist, with IC 50 s of 2.9 nM, 2 nM, and 1.7 nM for M1, M2, and M3 receptors, respectively. Ipratropium bromide hydrate relaxes smooth muscle, can be used in the research for COPD (chronic obstructive pulmonary disease) and asthma [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Sch 1000 bromide hydrate. CAS No. 66985-17-9. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg. Product ID: HY-B1332. | |
| Ipriflavone | Ipriflavone is a synthetic isoflavone derivative used to suppress bone resorption. Uses: Scientific research. Group: Signaling pathways. CAS No. 35212-22-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-N0094. | |
| Iprindole | Iprindole, a tricyclic indole antidepressant, is a weak inhibitor of the uptake of noradrenaline and 5-HT [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 5560-72-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12392. | |
| Iprobenfos | Iprobenfos is an organophosphorus fungicide and is widely used to control the rice blast fungus. Iprobenfos is also a choline biosynthesis inhibitor [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 26087-47-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-B1863. | |
| Iprodione | Iprodione is an orally active diformimide fungicide. Iprodione can specifically cause oxidative damage by producing free radicals (ROS). Iprodione is also an antiandrogen agent that delays adolescent development in rats and reduces sexual behavior and reproductive ability in rats [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 36734-19-7. Pack Sizes: 10 mM * 1 mL; 250 mg; 500 mg; 1 g. Product ID: HY-B1978. | |
| Iproniazid | Iproniazid is a non-selective, irreversible monoamine oxidase (MAO) inhibitor of the hydrazine class. Iproniazid has antidepressive activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 54-92-2. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B0886A. | |
| Iproniazid phosphate | Iproniazid phosphate is a non-selective, irreversible monoamine oxidase (MAO) inhibitor of the hydrazine class. Iproniazid phosphate has antidepressive activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 305-33-9. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B0886. | |
| Ipronidazole | Ipronidazole (RO-71554) is an orally active antihistomonal agent, which prevents and ameliorates enterohepatitis in turkeys. Ipronidazole can promotes turkey growth when supplied in feed or drinking water [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RO-71554. CAS No. 14885-29-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-151217. | |
| Ipsapirone | Ipsapirone (TVX Q 7821) is an anxiolytic compound and a 5-HT 1A receptor partial agonist. Ipsapirone (TVX Q 7821) also exhibits 5-HT 1A receptor antagonistic effect, and only at high doses it can also produce an inhibitory effect on 5-HT 2 and the α 1 -adrenergic function [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TVX Q 7821 free base. CAS No. 95847-70-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19686. | |
| IPSU | IPSU is a selective, orally available and brain penetrant OX2R antagonist with a pK i of 7.85. Uses: Scientific research. Group: Signaling pathways. CAS No. 1373765-19-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-13796. | |
| Iptacopan | Iptacopan (LNP023) is a first-in-class, orally bioavailable, highly potent and highly selective factor B inhibitor with an IC 50 value of 10 nM. Iptacopan shows direct, reversible, and high-affinity binding to human factor B with a K D of 7.9 nM. Iptacopan targets the underlying cause of complement 3 glomerulopathy (C3G) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LNP023. CAS No. 1644670-37-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-127105. | |
| Iptacopan hydrochloride | LNP023 hydrochloride is an orally bioavailable, highly potent and highly selective factor B inhibitor. LNP023 shows direct, reversible, and high-affinity binding to human factor B with a K D of 7.9 nM. LNP023 inhibits factor B with an IC 50 value of 10 nM [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LNP023 hydrochloride. CAS No. 1646321-63-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-127105A. | |
| Iptakalim hydrochloride | Iptakalim hydrochloride, a lipophilic para-amino compound, is a novel ATP-sensitive potassium channel (K ATP ) opener, as well as an α 4 β 2 -containing nicotinic acetylcholine receptor (nAChR) antagonist [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 642407-63-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-108069. | |
| IPTG | IPTG is a molecular mimic of allolactose, a lactose metabolite that triggers transcription of the lac operon, and it is therefore used to induce protein expression where the gene is under the control of the lac operator. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Isopropyl β-D-thiogalactoside. CAS No. 367-93-1. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-15921. | |
| IQ 1 | IQ 1 is a Wnt/β-catenin/CBP signalling sustainer. IQ 1 maintains long-term expansion of Wnt/β-catenin -driven mouse embryonic stem cells (ESCs) and prevents spontaneous differentiation by enhancing β-catenin/CBP -mediated transcription and preventing conversion to β-catenin/p300 -mediated transcription. IQ-1 regulates Wnt signalling by interacting with PR72/130. IQ 1 can be used in study of ESCs expansion [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 331001-62-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10593. | |
| IQ-3 | IQ-3 is a specific inhibitor of the c-Jun N-terminal kinase (JNK) family, with preference for JNK3. IQ-3 exhibits K d values of 0.24 μM, 0.29 μM and 0.066 μM for JNK1, JNK2 and JNK3, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 312538-03-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107600. | |
| IR-780 | IR780 is a prototypic NIR heptamethine cyanine agent, with a high molar extinction coefficient. The maximum excitation wavelength of IR780 was 777-780 nm, and the maximum emission wavelength was 798-823 nm. IR780 can be used in cancer PTT/PDT and imaging [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 207399-07-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D1063. | |
| IR-783 | IR-783 (ADS 780WS) is a near-infrared (NIR) heptamethine cyanine fluorescent probe. IR-783 significantly inhibits tumour growth and induces apoptosis in MDA-MB-231 xenograft model. IR-783 can be used to study breast cancer [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: ADS 780WS. CAS No. 115970-66-6. Pack Sizes: 10 mM * 1 mL; 10 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-139109. | |
| IR-797 chloride | IR-797 chloride is a near-infrared (NIR) dye. IR 797 has absorption maxima near 700 nm. IR-797 shows some aggregation-induced-emission (AIE) properties. IR-797 shows shows cytotoxic [1] [2]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 110992-55-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D1504. | |
| IR 813 tosylate | IR 813 tosylate is a near-infrared (NIR) fluorescent dye (λ ex =815 nm, λ em =840 nm) and can be used for visualizing regional lymph nodes in mice [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 134127-48-3. Pack Sizes: 10 mM * 1 mL; 250 mg; 500 mg; 1 g. Product ID: HY-W248594. | |
| IRAK inhibitor 4 | IRAK inhibitor 4 is an interleukin-1 receptor associated kinase 4( IRAK4 ) inhibitor. Uses: Scientific research. Group: Signaling pathways. CAS No. 1012104-68-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-13278. | |
| Irbesartan | Irbesartan (SR-47436) is an orally active Ang II type 1 (AT1) receptor blocker (ARB). Irbesartan can relax the blood vessels, low blood pressure and increase the supply of blood and oxygen to the heart. Irbesartan can be used for the research of high blood pressure, heart failure, and diabetic kidney disease [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SR-47436; BMS-186295. CAS No. 138402-11-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-B0202. | |
| Irdabisant | Irdabisant (CEP-26401) is a selective, orally active and blood-brain barrier (BBB) penetrant histamine H3 receptor (H3R) inverse agonist/inverse agonist with K i values of 7.2 nM and 2.0 nM for rat H3R and human H3R, respectively. Irdabisant has relatively low inhibitory activity against hERG current with an IC 50 of 13.8 μM. Irdabisant has cognition-enhancing and wake-promoting activities in the rat social recognition model. Irdabisant can be used to research schizophrenia or cognitive impairment [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CEP-26401. CAS No. 1005402-19-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-109968. | |
| IRF1-IN-1 | IRF1-IN-1 (Compound I-2) is an IRF1 inhibitor. IRF1-IN-1 decreases the recruitment of IRF1 to the promoter of CASP1. IRF1-IN-1 inhibits cell death signaling pathway (i.e., cleavage of Caspase 1 , GSDMD , IL-1 and PARP1 ). IRF1-IN-1 has a protective effect on ionizing radiation-induced inflammatory skin injury [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 701225-07-2. Pack Sizes: 10 mg; 25 mg; 50 mg. Product ID: HY-171006. | |
| Iridin | Iridin is an isoflavone isolated from Iris milesii [1]. Uses: Scientific research. Group: Natural products. CAS No. 491-74-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N3011. | |
| Iridium(III) chloride hydrate | Iridium(III) chloride (hydrate) (Iridium trichloride (hydrate)) is a biochemical reagent that can be used as a biological material or organic compound for life science related research [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Iridium trichloride hydrate. CAS No. 14996-61-3. Pack Sizes: 100 mg; 250 mg. Product ID: HY-W021022. | |
| Irigenin | Irigenin is a is a lead compound, and mediates its anti-metastatic effect by specifically and selectively blocking α9β1 and α4β1 integrins binding sites on C-C loop of Extra Domain A (EDA). Irigenin shows anti-cancer properties. It sensitizes TRAIL-induced apoptosis via enhancing pro-apoptotic molecules in gastric cancer cells [1]. Uses: Scientific research. Group: Natural products. CAS No. 548-76-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 20 mg; 50 mg; 100 mg. Product ID: HY-N2587. | |
| Irinotecan | Irinotecan ((+)-Irinotecan) is a topoisomerase I inhibitor, preventing religation of the DNA strand by binding to topoisomerase I-DNA complex [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (+)-Irinotecan; CPT-11; VAL-413(free base). CAS No. 97682-44-5. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-16562. | |
| Irinotecan-d10 | Irinotecan-d 10 is a deuterium labeled Irinotecan ((+)-Irinotecan). Irinotecan ((+)-Irinotecan) is a topoisomerase I inhibitor, preventing religation of the DNA strand by binding to topoisomerase I-DNA complex[1]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: (+)-Irinotecan-d10; CPT-11-d10; VAL-413-d10. CAS No. 718613-28-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-16562S. | |
| Irinotecan-d10 hydrochloride | Irinotecan-d 10 (hydrochloride) is the deuterium labeled Irinotecan. Irinotecan ((+)-Irinotecan) is a topoisomerase I inhibitor, preventing religation of the DNA strand by binding to topoisomerase I-DNA complex[1][2]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 718612-62-5. Pack Sizes: 1 mg. Product ID: HY-16562S1. | |
| Irinotecan hydrochloride | Irinotecan hydrochloride ((+)-Irinotecan hydrochloride) is a topoisomerase I inhibitor mainly used to treat colon cancer and rectal cancer [1]. Uses: Scientific research. Group: Natural products. Alternative Names: (+)-Irinotecan hydrochloride; CPT-11 hydrochloride; VAL-413. CAS No. 100286-90-6. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-16562A. | |
| Irinotecan hydrochloride trihydrate | Irinotecan hydrochloride trihydrate ((+)-Irinotecan hydrochloride trihydrate) is a topoisomerase I inhibitor with antitumor activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (+)-Irinotecan hydrochloride trihydrate; CPT-11 hydrochloride trihydrate. CAS No. 136572-09-3. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-16568. | |
| Irisflorentin | Irisflorentin, a naturally occurring isoflavone, is an abundant active constituent in Belamcanda chinensis. Irisflorentin markedly reduces the transcriptional and translational levels of inducible nitric oxide synthase (iNOS) as well as the production of NO. Anti-inflammatory activity [1]. Uses: Scientific research. Group: Natural products. CAS No. 41743-73-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 20 mg. Product ID: HY-N0268. | |
| Irloxacin | Irloxacin (Pirfloxacin) is a quinolone antibacterial agent. Irloxacin shows greater activity with an acid pH. Irloxacin has a good in vitro antimicrobial spectrum against both gram-positive and gram-negative bacteria. Orally active [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Pirfloxacin. CAS No. 91524-15-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-105033. | |
| (-)-Irofulven | (-)-Irofulven (MGI 114), an Illudin S analog, is a DNA alkylating agent. (-)-Irofulven inhibits the replication of DNA, induces tumor cells apoptosis , and has potent antitumor activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MGI 114; 6-Hydroxymethylacylfulvene; NSC 683863. CAS No. 158440-71-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-14429. | |
| Iron dextran | Iron dextran (Fe dextran) can be used in the study of iron-deficiency anemia in animals [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Fe dextran. CAS No. 9004-66-4. Pack Sizes: 5 mL; 25 mL. Product ID: HY-107928. | |
| Iron(II) fumarate | Iron (II) fumarate is an orally effective active dietary supplement. Iron (II) fumarate can alleviate metabolic damage and damage to silkworms caused by cypermethrin (HY-123178). Iron (II) fumarate can be used for research on iron deficiency anemia [1] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ferrous fumarate. CAS No. 141-01-5. Pack Sizes: 500 mg; 1 g. Product ID: HY-B1651. | |
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