MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Furafylline | Furafylline is a potent and selective inhibitor of human cytochrome P450IA2 with an IC 50 of 0.07 μM. Uses: Scientific research. Group: Signaling pathways. CAS No. 80288-49-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107204. |  |
| Furaltadone hydrochloride | Furaltadone hydrochloride is an orally active antibacterial agent that can be used for the study of intestinal Salmonella infections. Furaltadone has in vitro inhibitory effects on Staphylococcus. In addition, Furaltadone shows inhibitory effects on allergic reactions [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Altafur hydrochloride. CAS No. 3759-92-0. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-B1148. | |
| Furamidine dihydrochloride | Furamidine dihydrochloride (DB75 dihydrochloride) is a selective protein arginine methyltransferase 1 (PRMT1) inhibitor with an IC 50 of 9.4 μM. Furamidine dihydrochloride is selective for PRMT1 over PRMT5, PRMT6, and PRMT4 (CARM1) (IC 50 s of 166 μM, 283 μM, and >400 μM, respectively). Furamidine dihydrochloride is a potent, reversible and competitive tyrosyl-DNA phosphodiesterase 1 (TDP-1) inhibitor. Inhibition of TDP-1 by Furamidine dihydrochloride is effective both with single- and double-stranded DNA substrates but is slightly stronger with the duplex DNA. Furamidine dihydrochloride is also an antiparasite agent [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DB75 dihydrochloride; NSC 305831 dihydrochloride. CAS No. 55368-40-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110137. | |
| Furaneol | Furaneol is mainly isolated from American grape ( Vitis labrusca ) and its hybrid grape. Furaneol is an important aroma compound in fruits and contribute to the strawberry-like note in some wines [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Strawberry furanone. CAS No. 3658-77-3. Pack Sizes: 10 mM * 1 mL; 1 g. Product ID: HY-N7093. | |
| Furaprofen | Furaprofen (R803) is an effective HCV replication inhibitor. Furaprofen (R803) is substantially more potent against genotype 1a and 1b replicons ( EC 50 , ~30 nM) than against the genotype 2a replicon (EC 50 , ~1,000 nM). Uses: Scientific research. Group: Signaling pathways. Alternative Names: R803. CAS No. 67700-30-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-U00213. | |
| Fura Red AM | Fura Red AM is a fluorescent probe that can be used to visualize [Ca(2+)] distribution in the cytoplasm of undifferentiated cells. Fura Red AM operates at an excitation wavelength of 488 nm [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 218280-33-2. Pack Sizes: 1 mg. Product ID: HY-D1903. | |
| Furazolidone | Furazolidone is a monoamine oxidase (MAO) inhibitor with antiproliferative, apoptosis-inducing and differentiation-promoting activities. Furazolidone may inhibit leukemia fusion protein-mediated bone marrow transformation by upregulating the stability of the tumor suppressor protein p53. Furazolidone exhibits anti-leukemic activity in acute myeloid leukemia (AML) cell lines and can be used for anti-AML research [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 67-45-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B1336. | |
| Furazolidone (Standard) | Furazolidone (Standard) is the analytical standard of Furazolidone. This product is intended for research and analytical applications. Furazolidone is a nitrofuran derivative with antiprotozoal and antibacterial activity. It inhibits AML1-ETO transformed cells with an IC50 of 12.7 μM. Uses: Scientific research. Group: Signaling pathways. CAS No. 67-45-8. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-B1336R. | |
| Furegrelate sodium | Furegrelate Sodium (U-63557A) is a potent, orally available, and selective thromboxane synthase inhibitor. Furegrelate Sodium inhibits human platelet microsomal thromboxane A2 (TxA2) synthase with an IC 50 of 15 nM. Furegrelate Sodium is being developed as an antiplatelet agent [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: U-63557A. CAS No. 85666-17-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-106080A. | |
| Furfuryl acetate | Furfuryl acetate can be used in the synthesis of 5-acetoxymethyl-2-vinylfuran and 5-hydroxymethyl-2-vinylfuran [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 623-17-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-W010321. | |
| Furosemide | Furosemide is a potent and orally active inhibitor of Na + /K + /2Cl - (NKCC) cotransporter , NKCC1 and NKCC2 [1]. Furosemide is also a GABA A receptors antagonist and displays 100-fold selectivity for α6-containing receptors than α1-containing receptors. Furosemide acts as a loop diuretic and used for the study of congestive heart failure, hypertension and edema [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 54-31-9. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0135. | |
| Furosemide sodium | Furosemide sodium is a potent and orally active inhibitor of Na + /K + /2Cl - (NKCC) cotransporter , NKCC1 and NKCC2 [1]. Furosemide sodium is also a GABA A receptors antagonist and displays 100-fold selectivity for α6-containing receptors than α1-containing receptors. Furosemide sodium acts as a loop diuretic and used for the study of congestive heart failure, hypertension and edema [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 41733-55-5. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-B0135A. | |
| Furosemide (Standard) | Furosemide (Standard) is the analytical standard of Furosemide. This product is intended for research and analytical applications. Furosemide is a potent and orally active inhibitor of Na + /K + /2Cl - (NKCC) cotransporter , NKCC1 and NKCC2 [1]. Furosemide is also a GABA A receptors antagonist and displays 100-fold selectivity for α6-containing receptors than α1-containing receptors. Furosemide acts as a loop diuretic and used for the study of congestive heart failure, hypertension and edema [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 54-31-9. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0135R. | |
| Fusaric acid | Fusaric acid is a potent dopamine β-hydroxylase inhibitor. Uses: Scientific research. Group: Natural products. CAS No. 536-69-6. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-128483. | |
| Fusicoccin | Fusicoccin (Fusicoccin A), a fungal pytotoxin, is a stabilizer of specific 14-3-3 protein-protein interactions. Fusicoccin sabilizes H + -ATPase/14-3-3 cmplex in pants, maintaining the enzyme in activated state. Fusicoccin also stabilizes 14-3-3 protein interactions with binding partners containing a C-terminal 14-3-3 recognition motif (a mode 3 motif), such as ERα, GPIbα, TASK3, CTFR, and p53. Fusicoccin induces apoptosis in cancer cells and has anticancer activity [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Fusicoccin A. CAS No. 20108-30-9. Pack Sizes: 1 mg. Product ID: HY-122815. | |
| Fusidic acid | Fusidic acid (Fusidate) a bacteriostatic antibiotic produced from the Fusidium coccineum fungus, belongs to the class of steroids. Fusidic acid has no corticosteroid effects. Fusidic acid inhibits the growth of bacteria by preventing the release of translation elongation factor G (EF-G) from the ribosome. Fusidic acid holds promise for research in anticancer and anti-infective applications. [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. Alternative Names: Fusidate; SQ-16603. CAS No. 6990-6-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B1350. | |
| Fusion Inhibitory Peptide | Fusion Inhibitory Peptide (Z-D-Phe-Phe-Gly-OH, FIP, Virus Replication Inhibitory Peptide) is a potent inhibitor of the virus replication, by inhibiting the membrane fusing activity of a viral glycoprotein [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Z-D-Phe-Phe-Gly-OH; FIP; Virus Replication Inhibitory Peptide. CAS No. 75539-79-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-114437. | |
| Fustin | Fustinis ((±)-Fustin; 3,7,3',4'-Tetrahydroxyflavanone) is a potent amyloid β (Aβ) inhibitor. Fustinis ((±)-Fustin; 3,7,3',4'-Tetrahydroxyflavanone) increases the expression of acetylcholine (ACh) levels, choline acetyltransferase (ChAT) activity, and ChAT gene induced by Aβ (1-42). Fustinis ((±)-Fustin; 3,7,3',4'-Tetrahydroxyflavanone) decreases in acetyl cholinesterase (AChE) activity and AChE gene expression induced by Aβ (1-42). Fustinis ((±)-Fustin; 3,7,3',4'-Tetrahydroxyflavanone) increases muscarinic M1 receptor gene expression and muscarinic M1 receptor binding activity. Fustinis ((±)-Fustin; 3,7,3',4'-Tetrahydroxyflavanone) can be used for Alzheimer's disease research [1]. Uses: Scientific research. Group: Natural products. Alternative Names: (±)-Fustin; 3,7,3',4'-Tetrahydroxyflavanone. CAS No. 20725-03-5. Pack Sizes: 1 mg. Product ID: HY-N8376. | |
| Futibatinib | Futibatinib (TAS-120) is an orally bioavailable, highly selective, and irreversible FGFR inhibitor, with IC 50 s of 3.9, 1.3, 1.6, and 8.3 nM for FGFR 1-4, respectively. Futibatinib inhibits mutant and wild-type FGFR2 with similar IC 50 s (wild-type FGFR2=0.9?nM; V5651=1-3?nM; N550H=3.6?nM; E566G=2.4?nM) [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TAS-120. CAS No. 1448169-71-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100818. | |
| Futoquinol | Futoquinol is a neolignan isolated from the dried aerial parts of Piper kadsura (Piperaceae). Futoquinol potently inhibits NO production in microglia cells. Futoquinol has anti-neuroinflammatory activities [1]. Uses: Scientific research. Group: Natural products. CAS No. 28178-92-9. Pack Sizes: 1 mg. Product ID: HY-N3915. | |
| Futuximab | Futuximab is a chimeric monoclonal antibody targeting non-overlapping epitopes on EGFR. Futuximab has antineoplastic activity [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1310460-85-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99628. | |
| Fuzapladib | Fuzapladib (IS-741), an orally active leukocyte-function-associated antigen type 1 (LFA-1) activation inhibitor, is a leukocyte adhesion molecule. Fuzapladib is also a phospholipase A2 (PLA2) inhibitor. Fuzapladib exerts anti-inflammatory effects by inhibiting leukocyte migration into the inflammatory site [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IS-741. CAS No. 141283-87-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19151. | |
| Fuzapladib sodium | Fuzapladib (IS-741) sodium, an orally active leukocyte-function-associated antigen type 1 (LFA-1) activation inhibitor, is a leukocyte adhesion molecule. Fuzapladib sodium is also a phospholipase A2 (PLA2) inhibitor. Fuzapladib sodium exerts anti-inflammatory effects by inhibiting leukocyte migration into the inflammatory site [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IS-741 sodium. CAS No. 141284-73-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19151A. | |
| FX1 | FX1 is a potent and specific BCL6 inhibitor, with an IC 50 of around 35 μM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1426138-42-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-102027. | |
| FX-11 | FX-11 is a potent, selective, reversible and competitive lactate dehydrogenase A (LDHA) inhibitor, with a Ki of 8 ?M. FX-11 reduces ATP levels and induces oxidative stress, ROS production and cell death. FX-11 shows antitumor activity in lymphoma and pancreatic cancer xenografts[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LDHA Inhibitor FX11. CAS No. 213971-34-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16214. | |
| FX-909 | FX-909 is a covalent peroxisome proliferator-activated receptor gamma ( PPARG ) inverse agonist. FX-909 can be used for the research of cancer [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2924573-90-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153344. | |
| FXIIIa-IN-1 sodium | C.I.Reactive Black 5 (Technical Grade) is a biological molecule. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Reactive Black 5. CAS No. 17095-24-8. Pack Sizes: 100 mg; 250 mg; 500 mg. Product ID: HY-W783421. | |
| FzM1 | FzM1 is a negative allosteric modulator (NAM) of Frizzled receptor FZD4. FzM1 reduces WNT5A-dependent WNT responsive element (WRE) activity (log EC 50inh =-6.2). FzM1 binds to an allosteric binding site located in intracellular loop 3 (ICL3) of FZD4 and alters the conformation of the receptor, ultimately inhibiting the WNT/β-catenin cascade [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1680196-54-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116553. | |
| G0-C14 | G0-C14 is a cationic lipid-like compound alkyl-modified polyamidoamine (PAMAM) dendrimer. G0-C14 involves in the preparation of a series of macrophage-targeted nanoparticles (NPs). NPs can be used for agent and vaccine delivery [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 1510653-27-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-152229. | |
| G-1 | G-1 is a nonsteroidal, high-affinity and selective agonist of GPR30 with a K i of 11 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 881639-98-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-107216. | |
| G12 | G12 (Ras 5-17) is a wild-type Ras peptide consisted of amino acids 5-17 (KLVVVGAGGVGKS). G12 can be used as a control of mutant Ras peptides studies (such V12) [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Ras 5-17. CAS No. 162550-82-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P2360. | |
| G140 | G140 is a potent and selective inhibitor of cyclic GMP-AMP synthase (cGAS), with IC50s of 14.0?nM and 442?nM for h-cGAS and m-cGAS, respectively. G140 has anti-inflammatory activity[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2369751-07-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-133916. | |
| G15 | G15 is a high affinity and selective G-protein-coupled estrogen receptor (GPER/GPR30) antagonist with a K i of 20 nM [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1161002-05-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103449. | |
| G150 | G150 is a highly selective human cyclic GMP-AMP synthase (h-cGAS) inhibitor with an IC 50 of 10.2 nM. G150 represses dsDNA-triggered interferon expression, and G150 can be used for the research of inflammatory [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2369751-30-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128583. | |
| G36 | G-36 is a cell-permeable nonsteroidal antagonist of the G protein-coupled estrogen receptor (GPER/GPR30), which selectively inhibits estrogen-mediated PI3K activation through GPER, rather than Er&alpha. G-36 also inhibits estrogen-mediated calcium mobilization (IC 50 =112 nM). G-36 is promising for research in the field of cancer [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1392487-51-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103450. | |
| G-418 disulfate | G-418 disulfate (Geneticin sulfate), is an aminoglycoside antibiotic, inhibits protein synthesis in eukaryotes and prokaryotes. G-418 disulfate is commonly used as a selective agent for eukaryotic cells [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Geneticin sulfate; Antibiotic G-418 sulfate. CAS No. 108321-42-2. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-17561. | |
| G43 | G43 is a potent, selective glucosyltransferase inhibitor, with the K d of 3.7μM and 46.9 nM for GtfB and GtfC, respectively. G43 has antibacterial to S. mutans in vitro and in vivo , and can be used for dental caries study [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 690693-02-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-155715. | |
| G-5555 | G-5555 is a potent p21-activated kinase 1 (PAK1) inhibitor with Kis of 3.7 nM and 11 nM for PAK1 and PAK2, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1648863-90-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-19635. | |
| G-5555 hydrochloride | G-5555 hydrochloride is a potent and selective p21-activated kinase 1 (PAK1) inhibitor with a Ki of 3.7 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 2319590-15-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-19635A. | |
| G6PD activator AG1 | G6PD activator AG1 is a potent and selective glucose-6-phosphate dehydrogenase (G6PD) agonist with an EC50 of 3 ?M. G6PD is an oxidoreductase that catalyzes the oxidation of glucose-6-phosphate to 6-phosphogluconolactone and the simultaneous reduction of NAD phosphate (NADP) to reduced NADP (NADPH). G6PD activator AG1 can reduce hemolysis of human erythrocytes[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 421581-52-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123962. | |
| G6PDi-1 | G6PDi-1 is a reversible and non-competitive glucose-6-phosphate dehydrogenase (G6PD) inhibitor with an IC 50 of 0.07 μM for human G6PD. G6PDi-1 depletes NADPH most strongly in lymphocytes. G6PDi-1 markedly decreases inflammatory cytokine production in T cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2457232-14-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W107464. | |
| G907 | G907 is a selective antagonist of ATP-binding cassette (ABC) transporter MsbA with anti-microbial activity. G907 inhibits E. coli MsbA with an IC 50 value of 18 nM. G907 traps MsbA in an inward-facing, lipopolysaccharide-bound conformation by wedging into an architecturally conserved transmembrane pocket [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2244035-16-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-125176. | |
| GA-017 | GA-017 is a potent and selective LATS1 and LATS2 (large tumor suppressor kinase 1/2) inhibitor, with IC50 values of 4.10 and 3.92 nM, respectively. GA-017 is an activator of cell proliferation. GA-017 promotes YAP/TAZ activation and nuclear translocation. GA-017 promotes cell growth under 3D culture conditions. GA-017 enhances the ex vivo formation of mouse intestinal organoids[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2351906-74-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147082. | |
| GA32 | GA32 (compound 58r) is potent androgen receptor (AR)/glucocorticoid receptor (GR) dual inhibitor with IC 50 values of 0.13 μM and 0.83 μM for AR and GR, respectively. GA32 inhibits the proliferation of Enzalutamide (HY-70002) resistance castration-resistant prostate cancer both in vitro and in vivo [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1386811-71-7. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-163340. | |
| Gabapentin | Gabapentin is a potent, orally active P/Q type Ca 2+ channel blocker. Gabapentin inhibits neuronal Ca 2+ influx and reduction of neurotransmitter release. Gabapentin is a GABA analog that can be used to relieve neuropathic pain [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 60142-96-3. Pack Sizes: 10 mM * 1 mL; 10 mg; 50 mg; 100 mg. Product ID: HY-A0057. | |
| Gabapentin enacarbil | Gabapentin enacarbil (XP-13512) is a prodrug of Gabapentin (HY-A0057) designed to be absorbed throughout the intestine by high-capacity nutrient transporters. Gabapentin is a potent, orally active P/Q type Ca 2+ channel blocker. Gabapentin enacarbil can be used for the study of Restless Legs Syndrome (RLS) and postherpetic neuralgia (PHN) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: XP-13512. CAS No. 478296-72-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-16216. | |
| Gabapentin hydrochloride | Gabapentin hydrochloride is a potent, orally active P/Q type Ca 2+ channel blocker. Gabapentin hydrochloride inhibits neuronal Ca 2+ influx and reduction of neurotransmitter release. Gabapentin hydrochloride is a GABA analog that can be used to relieve neuropathic pain [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 60142-95-2. Pack Sizes: 10 mM * 1 mL; 10 mg; 50 mg; 100 mg. Product ID: HY-A0057A. | |
| Gabazine | Gabazine is a selective and competitive antagonist of GABA A receptor , with an IC 50 of ~0.2 μM for GABA receptor. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SR95531. CAS No. 104104-50-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-103533. | |
| Gabexate mesylate | Gabexate mesylate (FOY) is is a competitive and non-antigenic synthetic inhibitor of trypsin-like serine proteinases. Gabexate mesylate inhibits human thrombin, urokinase, plasmin, and Factor Xa with K i s of 0.97, 1.3, 1.6, and 8.5 μM, respectively. Gabexate mesylate binds to human and bovine tryptase with K i s of 3.4 nM and 18 μM, respectively. Gabexate mesylate exerts an anticoagulant effect on the clotting activity of thrombin and has anti-inflammatory effect by viainhibition of NF-κB, proinflammatory cytokines, and nitric oxide. Gabexate mesylate is used for pancreatitis and disseminated intravascular coagulation [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FOY. CAS No. 56974-61-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0385. | |
| Gaboxadol hydrochloride | Gaboxadol hydrochloride (Lu 02-030 hydrochloride) is a potent agonist of the GABA A receptor and an antagonist of GABA C receptors ( IC 50 =25 μM). Gaboxadol hydrochloride displays a partial agonist efficacy on subunit α1β2γ2 with an ED 50 value of 143 μM, a full agonist efficacy at α5 subunit ( ED 50 =28-129 μM) and a superagonist efficacy at α4β3δ ( ED 50 =6 μM). Gaboxadol hydrochloride is a non-opioid agent [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Lu 02-030 hydrochloride; THIP hydrochloride. CAS No. 85118-33-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10233. | |
| Gadoterate meglumine | Gadoterate meglumine (Gd-DOTA) is a non-specific paramagnetic gadolinium complex used as a contrast enhancer in magnetic resonance imaging (MRI). Gadoterate meglumine, as a contrast agent in MRI, is able to shorten the longitudinal relaxation time (T1) of tissue, resulting in a brighter signal in MRI images. Gadoterate meglumine can be used for the study of the central nervous system (such as the brain and spinal cord), abdominal, pelvic organs, breast, bone and joint imaging, angiography, and cardiac electrophysiology [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Gd-DOTA; Magnescope; P-449. CAS No. 92943-93-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108760. | |
| Gadoteric acid | Gadoteric acid is a macrocyclic, paramagnetic, gadolinium-based contrast agent that can be used for magnetic resonance imaging (MRI) of the brain, spine, and related tissues. In particular, Gadoteric acid is able to detect and visualize areas of blood-brain barrier disruption and abnormal vascular distribution [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 72573-82-1. Pack Sizes: 100 mg; 250 mg. Product ID: HY-148465. | |
| Gadoxetate disodium | Gadoxetate (Gd-EOB-DTPA) Disodium is a contrast agent in magnetic resonance imaging (MRI) of the hepatobiliary system, which accumulates in normal, functioning hepatocytes. Gadoxetate Disodium aggravates liver fibrosis (LF) induced gadolinium deposition in the liver and deep cerebellar nuclei (DCN) of rats without significant acute histological alterations. Gadoxetate Disodium is used to evaluate focal liver lesions, such as hepatocellular carcinoma or dysplastic nodules [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Gd-EOB-DTPA disodium; ZK 139834. CAS No. 135326-22-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16219. | |
| GAGGVGKSA | GAGGVGKSA is a wild type KRAS G12D 9mer peptide. GAGGVGKSA can be used as an immunogenic neoantigen for cancer immunotherapy research [1]. Uses: Scientific research. Group: Peptides. CAS No. 1223335-84-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P3487. | |
| GAGGVGKSAL | GAGGVGKSAL is a wild-type KRAS G12D 10mer peptide. GAGGVGKSAL can be used as an immunogenic neoantigen for cancer immunotherapy research [1]. Uses: Scientific research. Group: Peptides. CAS No. 199477-18-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P3485. | |
| GAL-021 | GAL-021 is a potent BK Ca -channel blocker. GAL-021 inhibits K Ca 1.1 in GH3 cells. GAL-021 is a novel breathing control modulator that is based on selective modification of the almitrine pharmacophore. GAL-021 increases minute ventilation in rats and non-human primates [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1380341-99-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101422. | |
| Galactinol | Galactinol is a biochemical reagent. Galactinol scavenges hydroxyl radicals and protects plant cells from oxidative damage [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 3687-64-7. Pack Sizes: 10 mg; 25 mg. Product ID: HY-N9497. | |
| Galactose Oxidase, Dactylium dendroides | Galactose Oxidase, Dactylium dendroides (GOase) from fungus is often used in biochemical studies. Galactose oxidase is a type II copper metalloenzyme, and it containing a single polypeptide. Galactose oxidase catalyzes two-electron oxidation of primary alcohols to their corresponding aldehydes, coupling with the reduction of dioxygen to hydrogen peroxide [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GOase. CAS No. 9028-79-9. Pack Sizes: 50 U; 150 U; 450 U. Product ID: HY-P2910. | |
| Galactosylceramide | Galactosylceramide (GalC) is a galactosylceramide that has been implicated in many physiological and pathological phenomena. For example, important lysosomal storage disorders such as Gaucher disease (GD) and neurodegenerative diseases are characterized by GlcCer accumulation. Uses: Scientific research. Group: Signaling pathways. CAS No. 85305-88-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-151240. | |
| Galangin | Galangin (Norizalpinin) is an agonist/antagonist of the arylhydrocarbon receptor. Galangin (Norizalpinin) also shows inhibition of CYP1A1 activity. Uses: Scientific research. Group: Natural products. Alternative Names: Norizalpinin; 3,5,7-Trihydroxyflavone. CAS No. 548-83-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0382. | |
| Galanin (1-30), human | Galanin (1-30), human is a 30-amino acid neuropeptide, and acts as an agonist of GalR1 and GalR2 receptors , with K i s of both 1 nM. Uses: Scientific research. Group: Peptides. Alternative Names: Glanin. CAS No. 119418-04-1. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-P1127. | |
| Galanin (swine) | Galanin (swine), a neuropeptide, consists of 29 amino acids and contains a C-terminal amidated glycine. Galanin (swine) inhibits basal and stimulated insulin secretion both in vivo and in vitro under a variety of experimental conditions. Galanin (swine) is a galanin receptor agonist with pK i s of 9.63, 9.49, 9.02, 8.98, 8.01 and 8.14 at human GAL1, rat GAL1, human GAL2, rat GAL2, human GAL3 and rat GAL3 respectively [1]. Uses: Scientific research. Group: Peptides. CAS No. 88813-36-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1128. | |
| Galanthamine | Galanthamine is a potent acetylcholinesterase ( AChE ) inhibitor with an IC 50 of 500 nM. Uses: Scientific research. Group: Natural products. Alternative Names: Galantamine. CAS No. 357-70-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-76299. | |
| Galanthamine hydrobromide | Galanthamine hydrobromide (Galantamine hydrobromide) is a selective, reversible, competitive, alkaloid AChE inhibitor, with an IC 50 of 0.35 μM. Galanthamine hydrobromide is a potent allosteric potentiating ligand (APL) of human α 3 β 4 , α 4 β 2 , α 6 β 4 nicotinic receptors ( nAChRs ). Galanthamine hydrobromide is developed for the research of Alzheimer's disease (AD) [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Galantamine hydrobromide. CAS No. 1953-4-4. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-A0009. | |
| Galanthamine N-Oxide | Galanthamine N-Oxide is an alkaloid obtained from the bulbs of Zephyranthes concolor. Galanthamine N-Oxide inhibits electric eel acetylcholinesterase (AChE) with an EC 50 of 26.2 μM. Galanthamine N-Oxide is a prominent inhibitor of substrate accommodation in the active site of the Torpedo californica AChE (TcAChE), hAChE and hBChE enzymes [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 134332-50-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N7263. | |
| Galaxolide | Galaxolide can induce estrogenic activity ( Estrogen Receptor/ERR ), trigger oxidative stress and genotoxicity, and induce EROD and GST ( Glutathione S-transferase ) enzyme activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1222-05-5. Pack Sizes: 25 g; 50 g; 100 g. Product ID: HY-W100026. | |
| Galcanezumab | Galcanezumab (LY 2951742) is a humanized IgG4 monoclonal antibody against the CGRP ligand. Galcanezumab can be used for migraine or cluster headaches research [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: LY 2951742. CAS No. 1578199-75-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99021. | |
| Galegenimab | Galegenimab (FHTR 2163; RG 6147; RO 7171009), an anti- High-temperature requirement A1 (HTRA1) antibody fragment. Galegenimab can be used for age-related macular degeneration (AMD) research [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: FHTR 2163; RG 6147; RO 7171009. CAS No. 2403683-24-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99629. | |
| Galegine hydrochloride | Galegine hydrochloride, a guanidine derivative, contributes to weight loss in mice. Guanidine hydrochloride is the compound derived from G. officinalis , which gave rise to the biguanides, metformin and phenformin. Galegine hydrochloride activates AMPK in 3T3-L1 adipocytes and L6 myotubes, as well as in the H4IIE rat hepatoma and HEK293 human kidney cell lines. Galegine hydrochloride has antibacterial activity, with minimum inhibitory concentration of 4 mg/L against Staphylococcus aureus strains [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 2368870-39-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N0930B. | |
| Galeterone | Galeterone (TOK-001) is a multifunctional antiandrogen and CYP17 inhibitor ( IC 50 =47 nM) in castration resistant prostate cancer (CRPC). Uses: Scientific research. Group: Signaling pathways. Alternative Names: TOK-001; VN-124-1. CAS No. 851983-85-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-70006. | |
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