MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| GAPDH, rabbit muscle | Glyceraldehyde phosphate dehydrogenase (EC 1.2.1.12) is the target of anti-thymocyte and anti-apoptotic agents. Glyceraldehyde phosphate dehydrogenase catalyzes the chain oxidation of reduced nicotinamide adenine dinucleotide by perhydroxyl radicals [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GADPH; G3PDH; Glyceraldehyde phosphate dehydrogenase. CAS No. 9001-50-7. Pack Sizes: 100 U; 500 U. Product ID: HY-P2804. |  |
| Garadacimab | Garadacimab (CSL312) is a first-in-class, fully human IgG4 monoclonal antibody targeting activated factor XII (FXIIa). Garadacimab has the potential for hereditary angioedema research [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: CSL312. CAS No. 2162134-62-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99631. | |
| Garcinol | Garcinol, a polyisoprenylated benzophenone harvested from Garcinia indica , exerts anti-cholinesterase properties towards acetyl cholinesterase (AChE) and butyrylcholinesterase (BChE) with IC 50 s of 0.66 μM and 7.39 μM, respectively [1]. Garcinol also inhibits histone acetyltransferases ( HATs , IC 50 = 7 μM) and p300/CPB-associated factor ( PCAF , IC 50 = 5 μM). Garcinol has anti-inflammatory and anti-cancer activity [2]. Uses: Scientific research. Group: Natural products. CAS No. 78824-30-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-107569. | |
| Gardenia yellow | Gardenia yellow is an active member of crocin, increases mRNA expression of SIRT3 , and acts as an orally active antidepressant agent [1]. Uses: Scientific research. Group: Natural products. CAS No. 94238-00-3. Pack Sizes: 50 mg; 100 mg. Product ID: HY-N6675. | |
| Garenoxacin Mesylate hydrate | Garenoxacin (BMS284756) Mesylate hydrate is an orally active quinolone antibiotic and has a broad spectrum of activity against a wide array of gram-positive and gram-negative bacteria, anaerobes, and fastidious organisms [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS284756 Mesylate hydrate. CAS No. 223652-90-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17460A. | |
| Garetosmab | Garetosmab (REGN 2477) is a fully human IgG4 monoclonal antibody that specifically inhibits activin A. Garetosmab can be used for fibrodysplasia ossificans progressiva (FOP) research [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: REGN 2477. CAS No. 2097125-54-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99632. | |
| Gartisertib | Gartisertib (VX-803) is an ATP-competitive, orally active, and selective ATR inhibitor, with a Ki of <150 pM. Gartisertib potently inhibits ATR-driven phosphorylated checkpoint kinase-1 (Chk1) phosphorylation with an IC50 of 8 nM. Antitumor activity[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: VX-803; M4344; ATR inhibitor 2. CAS No. 1613191-99-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136270. | |
| Gastric mucin | Gastric mucin is a large glycoprotein which is thought to play a major role in the protection of the gastrointestinal tract from acid, proteases, pathogenic microorganisms, and mechanical trauma. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 84082-64-4. Pack Sizes: 500 mg; 10 g. Product ID: HY-B2196. | |
| Gastrin I, human | Gastrin I, human is the endogenous peptide produced in the stomach, and increases gastric acid secretion via cholecystokinin 2 (CCK2) receptor. Uses: Scientific research. Group: Peptides. CAS No. 10047-33-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1097. | |
| Gastrin-Releasing Peptide, human | Gastrin-Releasing Peptide, human (GRP) belongs to the bombesin-like peptide family, and is not a classical hypothalamic-hypophyseal regulatory hormone since it plays only a perfunctory role in the mediation of pituitary hormone release. Uses: Scientific research. Group: Peptides. CAS No. 93755-85-2. Pack Sizes: 500 μg; 1 mg; 5 mg; 10 mg. Product ID: HY-P0238. | |
| Gastrodin | Gastrodin, a main constituent of a Chinese herbal medicine Tianma, has been known to display anti-inflammatory effects. Gastrodin inhibits ethanol-induced hepatocellular apoptosis. Gastrodin inhibits H 2 O 2 -induced ferroptosis through its antioxidative effect. Gastrodin can be used for study of dizziness, epilepsy, stroke and dementia [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Gastrodine. CAS No. 62499-27-8. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-N0115. | |
| Gatifloxacin | Gatifloxacin (AM-1155; BMS-206584; PD135432) is a potent fluoroquinolone antibiotic with broad-spectrum antibacterial activity. Gatifloxacin inhibits bacterial type II topoisomerases ( IC 50 =13.8 μg/ml for S. aureus topoisomerase IV) and E. coli DNA gyrase ( IC 50 =0.109 μg/ml) [1]. Gatifloxacin can be used to treat bacterial conjunctivitis in vivo. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AM-1155; BMS-206584; PD135432. CAS No. 112811-59-3. Pack Sizes: 500 mg; 1 g; 5 g. Product ID: HY-10581. | |
| Gatifloxacin hydrochloride | Gatifloxacin hydrochloride (AM-1155; BMS-206584; PD135432) is a potent fluoroquinolone antibiotic with broad-spectrum antibacterial activity. Gatifloxacin hydrochloride inhibits bacterial type II topoisomerases ( IC 50 =13.8 μg/ml for S. aureus topoisomerase IV) and E. coli DNA gyrase ( IC 50 = 0.109 μg/ml) [1]. Gatifloxacin hydrochloride can be used to treat bacterial conjunctivitis in vivo. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AM-1155 hydrochloride; BMS-206584 hydrochloride; PD135432 hydrochloride. CAS No. 121577-32-0. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-10581A. | |
| Gatipotuzumab | Gatipotuzumab (PankoMab) is a humanized monoclonal antibody which recognizes the tumor-specific epitope of mucin-1 ( TA-MUC1 ). Gatipotuzumab reveals a potent tumor-specific antibody-dependent cell cytotoxicity (ADCC) [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: PankoMab. CAS No. 1264737-26-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99634. | |
| Gatralimab | Gatralimab (GZ-402668) is an IgG1 anti- CD52 monoclonal antibody [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: GZ-402668. CAS No. 1826020-80-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99635. | |
| Gavestinel | Gavestinel (GV 150526) is a selective and potent the glycine site of the NMDA receptor antagonist. Gavestinel has neuroprotectant effects [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GV 150526. CAS No. 153436-22-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-150138. | |
| GB1107 | GB1107 is a potent, selective, orally active inhibitor of Galectin-3 (Gal-3) with a Kd of 37 nM for human Galectin-3. GB1107 reduces human and mouse lung adenocarcinoma growth and blocks metastasis in the syngeneic model[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1978336-61-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114409. | |
| GB-88 | GB-88 is an oral, selective non-peptide antagonist of PAR2, inhibits PAR2 activated Ca2+ release with an IC50 of 2 ?M[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1416435-96-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120261. | |
| GBR 12783 dihydrochloride | GBR 12783 dihydrochloride is a specific, potent and selective dopamine uptake inhibitor that inhibits the [ 3 H]dopamine uptake by rat and mice striatal synaptosomes with IC 50 s of 1.8 nM and 1.2 nM, respectively. GBR 12783 dihydrochloride can improve memory performance and increase hippocampal acetylcholine release in rats [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 67469-75-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-100968. | |
| GBT1118 | GBT1118 is a potent and orally active allosteric modifier of hemoglobin oxygen affinity. GBT1118 increases tolerance to severe hypoxia[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1628799-51-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-153182. | |
| GC376 sodium | GC376 sodium is a 3CLpro inhibitor; inhibits the replication of viruses TGEV, FIPV and PTV with IC 50 values of 0.15, 0.2 and 0.15 μM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1416992-39-6. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-100721. | |
| GC7 Sulfate | GC7 Sulfate is a deoxyhypusine synthase ( DHPS ) inhibitor. Uses: Scientific research. Group: Signaling pathways. CAS No. 150417-90-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108314A. | |
| GCase modulator-1 | GCase modulator-1 (compound 9g), a derivative of Quinazoline, is a modulator of GCase (Glucosidase) (AC 50 =2.23 μM) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 796079-91-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-156287. | |
| GCN2iB | GCN2iB is an ATP-competitive inhibitor of a serine/threonine-protein kinase general control nonderepressible 2 (GCN2), with an IC50 of 2.4 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 2183470-12-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112654. | |
| GCN2-IN-1 | GCN2-IN-1 (A-92) is a potent general control nonderepressible 2 kinase (GCN2) inhibitor with an IC50 of <0.3 ?M in the enzyme assay and an IC50 of 0.3-3 ?M in the cell assay[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: A-92. CAS No. 1448693-69-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100877. | |
| GCN2-IN-6 | GCN2-IN-6 (Compound 6d) is a potent, and orally available GCN2 inhibitor confirmed by in-house enzymatic (IC50 of 1.8 nM) and cellular assays (IC50 of 9.3 nM). GCN2-IN-6 is also a eIF2? kinase PERK inhibitor with an IC50 of 0.26 nM (in enzymatic assay) and 230 nM (in cells)[1]. GCN2-IN-6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 2183470-09-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-130240. | |
| GDC-0152 | GDC-0152 is a potent IAPs inhibitor, and binds to the BIR3 domains of XIAP, cIAP1, cIAP2 and the BIR domain of ML-IAP with Ki values of 28 nM, 17 nM, 43 nM and 14 nM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 873652-48-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13638. | |
| GDC-0276 | GDC-0276 is a potent, selective, reversible and orally active NaV1.7 inhibitor with an IC50 value of 0.4 nM. GDC-0276 is well tolerated and exhibits a good pharmacokinetic profile. GDC-0276 has the potential for the treatment of pain and to address shortcomings of existing pain medications, such as addiction and off-target side effects[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1494581-70-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114237. | |
| GDC-0339 | GDC-0339 is a potent, orally bioavailable and well tolerated pan-Pim kinase inhibitor, with Kis of 0.03 nM, 0.1 nM and 0.02 nM for Pim1, Pim2 and Pim3, respectively. GDC-0339 is discovered as a potential treatment of multiple myeloma[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1428569-85-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16976. | |
| GDC-0623 | GDC-0623 (RG 7421) is a potent, ATP-uncompetitive inhibitor of MEK1 (Ki=0.13 nM, +ATP), and displays 6-fold weaker potency against HCT116 (KRAS (G13D), EC50=42 nM) versus A375 (BRAFV600E, EC50=7 nM). Uses: Scientific research. Group: Signaling pathways. Alternative Names: RG 7421; MEK inhibitor 1. CAS No. 1168091-68-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15610. | |
| GDC-0879 | GDC-0879 is a potent and selective B-Raf inhibitor with an IC50 of 0.13 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 905281-76-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-50864. | |
| GDC-0927 | GDC-0927 (SRN-927) is a potent, non-steroidal, orally bioavailable, selective estrogen receptor antagonist [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SRN-927. CAS No. 1642297-01-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111484. | |
| GDP-L-fucose | GDP-L-fucose is a nucleotide sugar that is a key substrate for the biosynthesis of fucose oligosaccharides, providing the fucose moiety for the oligosaccharides.The formation of GDP-L-fucose occurs through two pathways, the major ab initio metabolic pathway and the minor remedial metabolic pathway. GDP-L-fucose is associated with diabetes in rats[1][2]. Uses: Scientific research. Group: Natural products. CAS No. 15839-70-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134433. | |
| GE11 | GE11 is a active peptide and combines with colloidal drug delivery systems as smart carriers for antitumor drugs and can be used for cancer study[1]. Uses: Scientific research. Group: Peptides. CAS No. 875142-25-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P10128. | |
| Gedatolisib | Gedatolisib (PKI-587) is a highly potent dual inhibitor of PI3Kα , PI3Kγ , and mTOR with IC 50 s of 0.4 nM, 5.4 nM and 1.6 nM, respectively [1]. Gedatolisib is equally effective in both complexes of mTOR, mTORC1 and mTORC2 [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PKI-587; PF-05212384. CAS No. 1197160-78-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10681. | |
| Gedunin | Gedunin is a limonoid with anti-cancer, anti-viral, anti-inflammatory and insecticidal activities. Gedunin acts as a potent Hsp90 inhibitor and induces the degradation of Hsp90-dependent client proteins. Geduni may obstructs the entry of SARS-CoV-2 virus into human host cells and can be used for COVID-19 research [3]. Uses: Scientific research. Group: Natural products. CAS No. 2753-30-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-107577. | |
| Gefapixant | Gefapixant is an orally active and potent purinergic P2X3 receptor ( P2X3R ) antagonist, with IC 50 values of ~30 nM versus recombinant hP2X3 homotrimers and 100-250 nM at hP2X2/3 heterotrimeric receptors. Gefapixant can be used for the research of chronic cough and knee osteoarthritis [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-7264; AF-219. CAS No. 1015787-98-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101588. | |
| Gefapixant citrate | Gefapixant citrate is an orally active and potent purinergic P2X3 receptor ( P2X3R ) antagonist, with IC 50 values of ~30 nM versus recombinant hP2X3 homotrimers and 100-250 nM at hP2X2/3 heterotrimeric receptors. Gefapixant citrate can be used for the research of chronic cough and knee osteoarthritis [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-7264 citrate; AF-219 citrate. CAS No. 2310299-91-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101588A. | |
| Gefarnate | Gefarnate is a agent used for the treatment of gastritis and gastric ulcer, and has been proposed for use in the treatment of dry eye syndrome. Uses: Scientific research. Group: Signaling pathways. CAS No. 51-77-4. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B2206. | |
| Gefitinib | Gefitinib (ZD1839) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC 50 of 33 nM. Gefitinib selectively inhibits EGF-stimulated tumor cell growth (IC 50 of 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib also induces autophagy and cell apoptosis , which can be used for cancer related research, such as Lung cancer and breast cancer [1] [2] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ZD1839. CAS No. 184475-35-2. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-50895. | |
| Gefitinib-based PROTAC 3 | Gefitinib-based PROTAC 3, conjugating an EGFR binding element to a von Hippel-Lindau ligand via a linker, induces EGFR degradation with DC50s of 11.7 nM and 22.3 nM in HCC827(exon 19 del) and H3255 (L858R mutantion) cells, respectively[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2230821-27-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123921. | |
| Gefitinib hydrochloride | Gefitinib hydrochloride (ZD1839 hydrochloride) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC 50 of 33 nM. Gefitinib hydrochloride selectively inhibits EGF-stimulated tumor cell growth (IC 50 of 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib hydrochloride also induces autophagy. Gefitinib hydrochloride has antitumour activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ZD-1839 hydrochloride. CAS No. 184475-55-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-50895A. | |
| Gefurulimab | Gefurulimab (ALXN-1720) is a human-derived bispecific antibody against complement C5 and albumin that binds C5 and blocks its activation [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ALXN-1720. CAS No. 2456407-94-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99638. | |
| Gelatins | Gelatins is a non-toxic, non carcinogenic, biodegradable, and non irritating natural polymer derived from partial hydrolysis of collagen. Due to its strong liquid absorption and swelling ability, Gelatins has excellent hemostatic properties and can be used as a matrix material for the reduction, growth, and stability of metal nanoparticles. Gelatins can also be used for tumor cell culture and tumor therapy [1][2][3]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 9000-70-8. Pack Sizes: 50 mg; 100 mg. Product ID: HY-Y1365. | |
| Geldanamycin | Geldanamycin is a Hsp90 inhibitor with antimicrobial activity against many Gram-positive and some Gram-negative bacteria. Geldanamycin has anti-influenza virus H5N1 activities. Uses: Scientific research. Group: Natural products. CAS No. 30562-34-6. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15230. | |
| Gellan gum, for cell culture | Gellan gum is a linear microbial exopolysaccharide that can be used as a cell scaffold for both soft tissue and load bearing applications. Gellan gum has many advantages such as biocompatibility, biodegradability, nontoxic in nature, and physical stability in the presence of cations [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Agar substitute gelling agent, for cell culture. CAS No. 71010-52-1. Pack Sizes: 100 mg. Product ID: HY-125870. | |
| Gelsemine | Gelsemine, an alkaloid from the Chinese herb Gelsemium elegans , is effective in mitigating chronic pain. Antinociceptive effects. Uses: Scientific research. Group: Natural products. CAS No. 509-15-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-N0388. | |
| Gelucire 44/14 | Gelucire 44/14 is a potential and safe absorption enhancer for improving the absorption of poorly absorbable agents including insulin and calcitonin by pulmonary delivery. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 121548-04-7. Pack Sizes: 25 g; 50 g; 100 g. Product ID: HY-Y1892. | |
| Gemcabene | Gemcabene (PD-72953), a first-in-class lipid-lowering agent, lowers low-density lipoprotein cholesterol (LDL-C), decreases triglycerides, and raises high-density lipoprotein cholesterol (HDL-C) and lowers pro-inflammatory acute-phase protein, C-reactive protein (CRP), exerting anti-inflammatory activity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PD-72953. CAS No. 183293-82-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109567. | |
| Gemcabene calcium | Gemcabene calcium (PD-72953 calcium), a first-in-class lipid-lowering agent, lowers low-density lipoprotein cholesterol (LDL-C), decreases triglycerides, and raises high-density lipoprotein cholesterol (HDL-C) and lowers pro-inflammatory acute-phase protein, C-reactive protein (CRP), exerting anti-inflammatory activity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PD-72953 calcium. CAS No. 209789-08-2. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-109567A. | |
| Gemcitabine | Gemcitabine (LY 188011) is a pyrimidine nucleoside analog antimetabolite and an antineoplastic agent. Gemcitabine inhibits DNA synthesis and repair, resulting in autophagy and apoptosis [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY 188011. CAS No. 95058-81-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg; 1 g; 5 g. Product ID: HY-17026. | |
| Gemcitabine-13C,15N2 hydrochloride | Gemcitabine- 13 C, 15 N 2 (hydrochloride) is the 13 C and 15 N labeled Gemcitabine hydrochloride[1]. Gemcitabine Hydrochloride (LY 188011 Hydrochloride) is a pyrimidine nucleoside analog antimetabolite and an antineoplastic agent. Gemcitabine Hydrochloride inhibits DNA synthesis and repair, resulting in autophagyand apoptosis[2][3]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: LY 188011- 13 C, 15 N2 hydrochloride. CAS No. 2757566-59-7. Pack Sizes: 500 μg. Product ID: HY-B0003S. | |
| Gemcitabine elaidate | Gemcitabine elaidate (CP-4126) is lipophilic pro-agent of Gemcitabine. Gemcitabine elaidate is converted to Gemcitabine by esterases in order to be phosphorylated. Gemcitabine elaidate exhibits anti-tumor activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CP-4126; CO-101; Gemcitabine 5'-elaidate. CAS No. 210829-30-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13538. | |
| Gemcitabine elaidate hydrochloride | Gemcitabine elaidate (CP-4126) hydrochloride is lipophilic pro-agent of Gemcitabine. Gemcitabine elaidate hydrochloride is converted to Gemcitabine by esterases in order to be phosphorylated. Gemcitabine elaidate hydrochloride exhibits anti-tumor activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CP-4126 hydrochloride; CO-101 hydrochloride; Gemcitabine 5'-elaidate hydrochloride. CAS No. 2918768-08-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13538A. | |
| Gemcitabine hydrochloride | Gemcitabine Hydrochloride (LY 188011 Hydrochloride) is a pyrimidine nucleoside analog antimetabolite and an antineoplastic agent. Gemcitabine Hydrochloride inhibits DNA synthesis and repair, resulting in autophagy and apoptosis [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY 188011 hydrochloride. CAS No. 122111-03-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-B0003. | |
| Gemcitabine (Standard) | Gemcitabine (Standard) is the analytical standard of Gemcitabine. This product is intended for research and analytical applications. Gemcitabine (LY 188011) is a pyrimidine nucleoside analog antimetabolite and an antineoplastic agent. Gemcitabine inhibits DNA synthesis and repair, resulting in autophagy and apoptosis [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 95058-81-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17026R. | |
| Gemcitabine triphosphate trisodium | Gemcitabine triphosphate (trisodium) is one of the two nucleoside metabolites of Gemcitabine (HY-17026) in cells. The other is active diphosphate (dFdDTP). Gemcitabine triphosphate can be used as a standard in radio-labeled probe imaging studies, to identify tumors sensitive to Gemcitabine, and to evaluate Gemcitabine uptake and retention by cells[1]. Uses: Scientific research. Group: Natural products. Alternative Names: dFdCTP trisodium. Pack Sizes: 1 mg (100 mM * 17.57 ?L in Water); 5 mg (100 mM * 87.86 ?L in Water); 10 mg (100 mM * 175.72 ?L in Water). Product ID: HY-17026E. | |
| Gemfibrozil | Gemfibrozil is an activator of PPAR-α , used as a lipid-lowering agent; Gemfibrozil is also a nonselective inhibitor of several P450 isoforms, with K i values for CYP2C9, 2C19, 2C8, and 1A2 of 5.8, 24, 69, and 82 μM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CI-719. CAS No. 25812-30-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0258. | |
| Gemifloxacin mesylate | Gemifloxacin mesylate (SB-265805S; LB-20304a) is an orally active broad-spectrum quinolone antibacterial antibiotic. Gemifloxacin mesylate inhibits DNA synthesis by inhibiting DNA gyrase and Topoisomerase IV activities. Gemifloxacin mesylate has potent antibacterial activities against gram-positive bacteria in vitro efficacy study, particularly Streptococci and Staphylococci. Gemifloxacin mesylate has been used in the research of respiratory tract infections [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SB-265805S; LB-20304a. CAS No. 210353-53-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B1050. | |
| Gemigliptin | Gemigliptin (LC15-0444 ) is a highly selective, reversible and competitive dipeptidyl peptidase-4 ( DPP-4 ) inhibitor, with an IC 50 of 10.3 nM for human recombinant DPP-4. Gemigliptin exhibits potent anti-glycation properties. Gemigliptin can be used for the research of advanced glycation end products (AGE)-related diabetic complications [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LC15-0444. CAS No. 911637-19-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14892. | |
| Gemigliptin tartrate | Gemigliptin tartrate (LC15-0444 tartrate) is a highly selective, reversible and competitive dipeptidyl peptidase-4 ( DPP-4 ) inhibitor, with an IC 50 of 10.3 nM for human recombinant DPP-4. Gemigliptin tartrate exhibits potent anti-glycation properties. Gemigliptin tartrate can be used for the research of advanced glycation end products (AGE)-related diabetic complications [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LC15-0444 tartrate. CAS No. 1374639-74-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14892A. | |
| Gemtuzumab | Gemtuzumab is a monoclonal IgG4-κ antibody targeting CD33 antigen, which present on leukemic myeloblasts of acute myeloid leukemia (AML). Gemtuzumab can be used for synthesis of antibody-drug conjugate (ADC) , Gemtuzumab ozogamicin (HY-109539). Gemtuzumab ozogamicin consists of a cytotoxic derivative of Calicheamicin (a cytotoxic antibiotic), and a monoclonal antibody. Gemtuzumab ozogamicin can be used for the research of acute myeloid leukemia [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 220578-59-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99971. | |
| Gemtuzumab ozogamicin | Gemtuzumab ozogamicin is an antibody-drug conjugate (ADC) consisting of a humanized immunoglobulin (IgG4) antibody directed against CD33 that is conjugated to the cytotoxic agent Calicheamicin (HY-19609). Calicheamicin is a cytotoxic antibiotic. Gemtuzumab ozogamicin can be used for the research of acute myeloid leukemia (AML) [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 220578-59-6. Pack Sizes: 100 μg; 200 μg; 500 μg. Product ID: HY-109539. | |
| Genipin | Genipin ((+)-Genipin) is a natural crosslinking reagent derived from Gardenia jasminoides Ellis fruits. Genipin inhibits UCP2 (uncoupling protein 2) in cells. Genipin has a variety of bioactivities, including modulation on proteins, antitumor, anti-inflammation, immunosuppression, antithrombosis, and protection of hippocampal neurons. Genipin also can be used for type 2 diabetes research [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: (+)-Genipin. CAS No. 6902-77-8. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-17389. | |
| Geniposide | Geniposide is an iridoid glucoside extracted from Gardenia jasminoides Ellis fruits; exhibits a varity of biological activities such as anti-diabetic, antioxidative, antiproliferative and neuroprotective activities. Uses: Scientific research. Group: Natural products. CAS No. 24512-63-8. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg. Product ID: HY-N0009. | |
| Geniposidic acid | Geniposidic acid has radiation protection and anti-cancer activity. Uses: Scientific research. Group: Natural products. CAS No. 27741-01-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0010. | |
| Genistein | Genistein, a soy isoflavone, is a multiple tyrosine kinases (e.g., EGFR ) inhibitor which acts as a chemotherapeutic agent against different types of cancer, mainly by altering apoptosis , the cell cycle, and angiogenesis and inhibiting metastasis. Uses: Scientific research. Group: Natural products. Alternative Names: NPI 031L. CAS No. 446-72-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-14596. | |
| Genistin | Genistin (Genistine), an isoflavone belonging to the phytoestrogen family, is a potent anti-adipogenic and anti-lipogenic agent. Genistin attenuates cellular growth and promotes apoptotic cell death breast cancer cells through modulation of ERalpha signaling pathway [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Genistine; Genistoside; Genistein 7-O-β-D-glucopyranoside. CAS No. 529-59-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-N0595. | |
| Genkwanin | Genkwanin is a major non-glycosylated flavonoid with anti-flammatory activities. Uses: Scientific research. Group: Natural products. Alternative Names: Puddumetin. CAS No. 437-64-9. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0731. | |
| Gentamicin | Gentamicin, an orally active aminoglycoside antibiotic, inhibits the growth of both gram-positive and gram-negative bacteria and to inhibit several strains of mycoplasma in tissue culture. Gentamicin inhibits DNase I with an IC 50 of 0.57 mM [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1403-66-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0276A. | |
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