MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Glycine | Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors. Glycine is orally active. Glycine can be used to study cell protection, cancer, neurological diseases, and angiogenesis [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Natural products. CAS No. 56-40-6. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-Y0966. |  |
| Glycine-13C2 | Glycine- 13 C 2 is the 13 C-labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 67836-01-5. Pack Sizes: 10 mg; 25 mg. Product ID: HY-Y0966S3. | |
| Glycine-15N | Glycine- 15 N is the 15 N-labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors[1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 7299-33-4. Pack Sizes: 50 mg; 100 mg. Product ID: HY-Y0966S. | |
| Glycine-2-13C | Glycine-2- 13 C is the 13 C-labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 20220-62-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-Y0966S2. | |
| Glycine-2-13C,15N | Glycine-2- 13 C, 15 N is the 13 C- and 15 N-labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 91795-59-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-Y0966S7. | |
| Glycine (Standard) | Glycine (Standard) is the analytical standard of Glycine. This product is intended for research and analytical applications. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors. Glycine is orally active. Glycine can be used to study cell protection, cancer, neurological diseases, and angiogenesis [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Natural products. CAS No. 56-40-6. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-Y0966R. | |
| Glycine tert-butyl ester hydrochloride | Glycine tert-butyl ester hydrochloride is a Glycine (HY-Y0966) derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 27532-96-3. Pack Sizes: 100 g. Product ID: HY-75331. | |
| Glycitein | Glycitein is a soy isoflavone used to study apoptosis and antioxidant [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Glycetein. CAS No. 40957-83-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N0016. | |
| Glycitin | Glycitin (Glycitein 7-O-β-glucoside) is a natural isoflavone with antibacterial, antiviral, anticancer, anti-inflammation, anti-aging and estrogenic effects. Glycitin may regulate osteoblasts through TGF-β or AKT signaling pathways in bone marrow stem cells (BMSCs) [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Glycitein 7-O-β-glucoside. CAS No. 40246-10-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N0012. | |
| Glycochenodeoxycholic acid | Glycochenodeoxycholic acid (Chenodeoxycholylglycine) is a relatively toxic bile salt generated in the liver from chenodeoxycholic acid and glycine. Glycochenodeoxycholic acid inhibits Autophagosome formation and impairs lysosomal function by inhibiting lysosomal proteolysis and increasing lysosomal pH in human normal liver cells, leading to the Apoptosis of human hepatocyte cells. Glycochenodeoxycholic acid induces stemness and chemoresistance via activating STAT3 signaling pathway in hepatocellular carcinoma cells (HCC). Glycochenodeoxycholic acid is promising for research in the field of cholestasis desease, hepatocellular carcinoma and primary sclerosing cholangitis (PSC) [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Chenodeoxycholylglycine. CAS No. 640-79-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-N2334. | |
| Glycochenodeoxycholic acid-d4 | Glycochenodeoxycholic acid-d 4 is the deuterium labeled Glycochenodeoxycholic acid. Glycochenodeoxycholic acid (Chenodeoxycholylglycine) is a bile acid formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. Glycochenodeoxycholic acid (Chenodeoxycholylglycine) induces hepatocyte apoptosis[1][2]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: Chenodeoxycholylglycine-d4. CAS No. 1201918-16-2. Pack Sizes: 1 mg. Product ID: HY-N2334S. | |
| Glycochenodeoxycholic acid sodium salt | Glycochenodeoxycholic acid sodium salt (Sodium glycochenodeoxycholate) is a relatively toxic bile salt generated in the liver from chenodeoxycholic acid and glycine. Glycochenodeoxycholic acid sodium salt inhibits Autophagosome formation and impairs lysosomal function by inhibiting lysosomal proteolysis and increasing lysosomal pH in human normal liver cells, leading to the Apoptosis of human hepatocyte cells. Glycochenodeoxycholic acid sodium salt induces stemness and chemoresistance via activating STAT3 signaling pathway in hepatocellular carcinoma cells (HCC). Glycochenodeoxycholic acid sodium salt is promising for research in the field of cholestasis desease, hepatocellular carcinoma and primary sclerosing cholangitis (PSC) [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Chenodeoxycholylglycine sodium salt; Sodium glycochenodeoxycholate. CAS No. 16564-43-5. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-N2334A. | |
| Glycocholic acid | Glycocholic acid is a bile acid with anticancer activity, targeting against pump resistance-related and non-pump resistance-related pathways [1]. Uses: Scientific research. Group: Natural products. CAS No. 475-31-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg. Product ID: HY-N1423. | |
| Glycocholic acid hydrate | Glycocholic acid hydrate is an endogenous metabolite. Uses: Scientific research. Group: Natural products. CAS No. 1192657-83-2. Pack Sizes: 100 mg. Product ID: HY-N1423B. | |
| Glycocholic acid sodium | Glycocholic acid sodium is an orally active bile acid with anticancer activity, targeting against pump resistance-related and non-pump resistance-related pathways [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 863-57-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg. Product ID: HY-N1423A. | |
| Glycocholic acid (Standard) | Glycocholic acid (Standard) is the analytical standard of Glycocholic acid. This product is intended for research and analytical applications. Glycocholic acid is a bile acid with anticancer activity, targeting against pump resistance-related and non-pump resistance-related pathways [1]. Uses: Scientific research. Group: Natural products. CAS No. 475-31-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N1423R. | |
| Glycocyamine | Glycocyamine (Guanidinoacetic acid), a precursor of creatine, is a replacement of dietary arginine and could support overall energy homeostasis of the bird. Uses: Scientific research. Group: Natural products. Alternative Names: Guanidinoacetic acid. CAS No. 352-97-6. Pack Sizes: 100 mg. Product ID: HY-W021448. | |
| Glycodehydrocholic acid | Glycodehydrocholic acid is a bile acid glycine conjugate. Glycodehydrocholic acid is used to diagnose cancer and other diseases [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3415-45-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N11416. | |
| Glycodeoxycholate Sodium | Glycodeoxycholate Sodium (Sodium glycyldeoxycholate) is a bile salt. Glycodeoxycholate Sodium has cytotoxicity to cancer cell, changes the permeability of the pancreatic duct and decreases glucose levels [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Sodium glycyldeoxycholate. CAS No. 16409-34-0. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-N1427. | |
| Glycodeoxycholic Acid | Glycodeoxycholic Acid is a natural product found in Streptomyces nigricans, Trypanosoma brucei and C. elegans. Glycodeoxycholic Acid induces hepatocyte necrosis and autophagy in patients with obstructive cholestasis [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 360-65-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-125731. | |
| Glycodeoxycholic acid-d4 | Glycodeoxycholic acid-d 4 is the deuterium labeled Glycodeoxycholic Acid. Glycodeoxycholic Acid is an endogenous metabolite. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 1069132-37-1. Pack Sizes: 1 mg. Product ID: HY-125731S. | |
| Glycodeoxycholic acid monohydrate | Glycodeoxycholic acid monohydrate is a nuclear receptor ligand. Uses: Scientific research. Group: Natural products. CAS No. 1079043-81-4. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-N1427A. | |
| Glycohyodeoxycholic acid | Glycohyodeoxycholic acid is a major metabolite of Hyodeoxycholic acid in humans. Glycohyodeoxycholic acid has preventative effects on gallstone formation [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 13042-33-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-126995. | |
| Glycol chitosan | Glycol chitosan is a chitosan derivative with ethylene glycol branches. Glycol chitosan enhances membrane permeability and leadkage in Glycine max Harosoy 63W cells. Glycol chitosan is biocompatible and biodegradable[1][2][3]. Glycol chitosan inhibits E. coli, S. aureus and S. enteritidis growths with MIC values of 4 ?g/mL, 32 ?g/mL and <0.5 ?g/mL, respectively[4]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 123938-86-3. Pack Sizes: 50 mg; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-135969. | |
| Glycolic acid | Glycolic acid is an inhibitor of tyrosinase , suppressing melanin formation and lead to a lightening of skin colour. Uses: Scientific research. Group: Natural products. Alternative Names: Hydroxyethanoic acid. CAS No. 79-14-1. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-W015967. | |
| Glycolithocholic acid | Glycolithocholic acid (Lithocholylglycine), an endogenous metabolite, is a glycine-conjugated secondary bile acid. Glycolithocholic acid can be used to diagnose ulcerative colitis (UC), non-alcoholic steatohepatitis (NASH) and primary sclerosing cholangitis (PSC) [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Lithocholylglycine. CAS No. 474-74-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116374. | |
| Glycolithocholic acid 3-sulfate disodium | Glycolithocholic acid 3-sulfate (disodium) inhibits replication of HIV-1 in vitro. Glycolithocholic acid 3-sulfate (disodium) can be used for the research of HIV infection and gallbladder disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Glycolithocholate sulfate disodium; Sulfolithocholylglycine disodium; SLCG disodium. CAS No. 64936-82-9. Pack Sizes: 1 mg. Product ID: HY-W587430. | |
| Glycolithocholic acid-d4 | Glycolithocholic acid-d 4 is the deuterium labeled Glycolithocholic acid. Glycolithocholic acid, an endogenous metabolite, is a glycine-conjugated secondary bile acid and can be used to diagnose ulcerative colitis (UC), non-alcoholic steatohepatitis (NASH) and primary sclerosing cholangitis (PSC) [1][2][3][4]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: Lithocholylglycine-d4. CAS No. 2044276-16-4. Pack Sizes: 500 μg; 1 mg. Product ID: HY-116374S. | |
| Glycolithocholic acid sodium | Glycolithocholic acid (Lithocholylglycine) sodium is the sodium salt of Glycolithocholic acid. Glycolithocholic acid is a glycine-conjugated secondary bile acid. Glycolithocholic acid can be used to diagnose ulcerative colitis (UC), non-alcoholic steatohepatitis (NASH) and primary sclerosing cholangitis (PSC) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Lithocholylglycine sodium. CAS No. 24404-83-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116374A. | |
| Glycol salicylate | Glycol salicylate is a derivative of salicylic acid and can be used to improve the aesthetic appearance of the skin, extracted from patent US 20150148320 A1. Uses: Scientific research. Group: Signaling pathways. CAS No. 87-28-5. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-B2208. | |
| Glycopyrrolate | Glycopyrrolate (Glycopyrronium bromide), a quaternary ammonium derivative, is a muscarinic receptor antagonist. Glycopyrrolate has bronchoprotective effect and produces a beneficial effect on blood pressure. Glycopyrrolate can be used for the research of bronchial diseases [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Glycopyrronium bromide; Glycopyrrolate bromide. CAS No. 596-51-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17465. | |
| Glycoursodeoxycholic acid | Glycoursodeoxycholic acid????????????-????????????????????. Uses: Scientific research. Group: Natural products. Alternative Names: Ursodeoxycholylglycine. CAS No. 64480-66-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-N1424. | |
| Glycoursodeoxycholic Acid-d4 | Glycoursodeoxycholic acid-d4 (Ursodeoxycholylglycine-d4) is the deuterium labeled Glycoursodeoxycholic acid. Glycoursodeoxycholic acid, a acyl glycine and a bile acid-glycine conjugate, is a metabolite of ursodeoxycholic acid[1][2]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 2044276-17-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N1424S. | |
| Glycozolidal | Glycozolidal (compound 12) is a carbazole alkaloid with antibacterial activity against P. gingivalis. Glycozolidal is cytotoxic against human gingival fibroblasts (HGFs) and monocytes (U937) in vitro with IC 50 values ??of 120.86 μg/mL and 97.74 μg/mL, respectively [1]. Uses: Scientific research. Group: Natural products. CAS No. 51971-09-6. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-N13286. | |
| Glycyl-DL-phenylalanine | Glycyl-DL-phenylalanine is a phenylalanine derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 721-66-4. Pack Sizes: 1 g; 5 g; 10 g. Product ID: HY-W014000. | |
| Glycylglycine | Glycylglycine is the simplest of all peptides and could function as a gamma-glutamyl acceptor. Uses: Scientific research. Group: Peptides. CAS No. 556-50-3. Pack Sizes: 10 mM * 1 mL; 500 mg; 5 g. Product ID: HY-D0889. | |
| Glycylglycine (Standard) | Glycylglycine (Standard) is the analytical standard of Glycylglycine. This product is intended for research and analytical applications. Glycylglycine is the simplest of all peptides and could function as a gamma-glutamyl acceptor. Uses: Scientific research. Group: Peptides. CAS No. 556-50-3. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D0889R. | |
| Glycyl-L-histidyl-L-lysine | Glycyl-L-histidyl-L-lysine is a tripeptide consisting of glycine, L-histidine and L-lysine residues joined in sequence. Glycyl-L-histidyl-L-lysine is a hepatotropic immunosuppressor and shows anxiolytic effect. Glycyl-L-histidyl-L-lysine and its copper complexes show good skin tolerance[1][2][3]. Uses: Scientific research. Group: Peptides. Alternative Names: GHK; Tripeptide-1. CAS No. 49557-75-7. Pack Sizes: 1 g; 5 g; 10 g; 25 g. Product ID: HY-P0046. | |
| Glycyl-L-phenylalanine | Glycyl-L-phenylalanine is a phenylalanine derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 3321-3-7. Pack Sizes: 1 g; 5 g. Product ID: HY-W013998. | |
| Glycyl-L-tyrosine | Glycyl-L-tyrosine is a dipeptide containing glycine and L-tyrosine [1]. Uses: Scientific research. Group: Natural products. CAS No. 658-79-7. Pack Sizes: 5 g. Product ID: HY-W009592. | |
| Glycyl-L-valine | Glycyl-L-valine is a dipeptide that contains glycine and valine. Uses: Scientific research. Group: Natural products. CAS No. 1963-21-9. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-W016785. | |
| Glycyrrhizic acid | Glycyrrhizic acid is a triterpenoid saponinl, acting as a direct HMGB1 antagonist, with anti-tumor, anti-diabetic activities. Uses: Scientific research. Group: Natural products. Alternative Names: Glycyrrhizin. CAS No. 1405-86-3. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg. Product ID: HY-N0184. | |
| Gly-Gly-Gly-PEG4-azide | Gly-Gly-Gly-PEG4-azide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Gly-Gly-Gly-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 3070260-22-6. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145066. | |
| Gly-Gly-Gly-PEG4-DBCO | Gly-Gly-Gly-PEG4-DBCO is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Gly-Gly-Gly-PEG4-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 2353409-80-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-140309. | |
| Gly-Gly-Phe-Gly | Gly-Gly-Phe-Gly is a peptide spacer and can be applied to Doxorubicin (HY-15142A) (DXR) conjugates [1]. Uses: Scientific research. Group: Peptides. CAS No. 200427-88-9. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P3669. | |
| Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH | Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is an ADC Linker that can be used to synthesize Drug-Linker Conjugates for ADC. Especially for the synthesis of Deruxtecan (HY-13631E), a toxic drug-linker conjugate[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1599440-20-6. Pack Sizes: 100 mg; 250 mg; 1 g; 5 g. Product ID: HY-45672. | |
| Gly-Gly-Phe-Gly-NH-O-CO-Exatecan | Gly-Gly-Phe-Gly-NH-O-CO-Exatecan is an ADC cytotoxin. Uses: Scientific research. Group: Signaling pathways. CAS No. 1599440-12-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13631M. | |
| Gly-Gly-Phe-Gly-NH-O-CO-Exatecan hydrochloride | Gly-Gly-Phe-Gly-NH-O-CO-Exatecan, as a drug-linker conjugate composed of linker Gly-Gly-Phe-Gly-NH-O-CO and Exatecan, can be used to prepare antibody conjugate drugs. Exatecan is a DNA topoisomerase I inhibitor that can be used in cancer research[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3053688-78-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13631F. | |
| GlyH-101 | GlyH-101 is a potent CFTR inhibitor. GlyH-101 also is a potent and reversible inhibitor of the VSORC conductance. GlyH-101 shows antiproliferative activity. GlyH-101 inhibits CFTR-like current and VSORC current [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 328541-79-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-18336. | |
| Gly-Mal-GGFG-Deruxtecan 2-hydroxypropanamide | Gly-Mal-GGFG-Deruxtecan 2-hydroxypropanamide is the drug-linker conjugate for ADC, containing ADC linker Gly-Mal-GGFG and ADC cytotoxin Deruxtecan 2-hydroxypropanamide[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2750623-07-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-153892. | |
| Glymidine sodium | Glymidine sodium is an oral active antidiabetic. Glymidine sodium is the inhibitor of hepatic lipolysis. Glymidine sodium inhibits the glucose formation and supresses the elevated pyruvate oxidation which results from the inhibition of endogenous lipid mobilization [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Gondafon; Glycodiazine. CAS No. 3459-20-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0231. | |
| Glyoxalase I | Glyoxalase I (Glo-I) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Glo-I. CAS No. 9033-12-9. Pack Sizes: 100 U. Product ID: HY-P2774. | |
| Glyoxalase I inhibitor 5 | Glyoxalase I inhibitor 5 (Compound 9h) is a glyoxalase I (Glo-I) inhibitor with an IC 50 of 1.28 μM. Glyoxalase I inhibitor 5 can be used as anticancer agent [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2455508-17-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-147647. | |
| Glyoxalic acid (50% in water) | Glyoxalic acid (NSC 27785) (50% in water) is an organic compound that is both an aldehyde and a carboxylic acid. Glyoxalic acid (50% in water) induces fluorescence. Glyoxalic acid (50% in water) is used to study neurons [1]. Uses: Scientific research. Group: Natural products. Alternative Names: NSC 27785; Formylformic acid; Oxalaldehydic acid. CAS No. 298-12-4. Pack Sizes: 500 mg (6.75 M * 1 mL in Water); 1 g (6.75 M * 2 mL in Water). Product ID: HY-79494. | |
| Glyphosate | Glyphosate, a non-selective systemic biocide with broad-spectrum activity, is an herbicidal derivative of the amino acid glycine. Glyphosate inhibits the enzymatic activity of the 5-endopyruvylshikimate 3-phosphate synthase (EPSPS) in the shikimic acid pathway, preventing the synthesis of the aromatic amino acids tyrosine, phenylalanine, and tryptophan. Glyphosate induces oxidative stress, neuroinflammation, and mitochondrial dysfunction, processes that lead to neuronal death by autophagia , necrosis , or apoptosis , as well as the appearance of behavioral and motor disorders [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 1071-83-6. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-B0863. | |
| Gly-Pro-AMC hydrobromide | Gly-Pro-AMC hydrobromide is a fluorescent dye, it can be used as a specific fluorescent substrate for detecting Dipeptidyl peptidase IV (DPP-IV) activity [1] [2]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 115035-46-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-137834. | |
| GM-90257 | GM-90257 is a microtubule acetylation inhibitor. GM-90257 binds directly to ?-tubulin. GM-90257 prevents the recruitment of ?-tubulin acetyltransferase 1 (?TAT1) to the K40 residue in ?-tubulin. GM-90257 causes Apoptosis, downregulates BCl-2, and activates JNK and PARP. GM-90257 has anticancer activity against breast cancer[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 315703-81-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-155956. | |
| GMBS | GMBS is a heterobifunctional cross-linker. GMBS can be used in chemical cross-linking of proteins coupled with mass spectrometry (CXMS) to study protein folding and to map the interfaces between interacting proteins [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 80307-12-6. Pack Sizes: 10 mg; 50 mg; 100 mg. Product ID: HY-W041994. | |
| GMQ | GMQ is a ASIC (acid-sensing ion) channel activator with an EC 50 value of 1.83 mM for ASIC3 at pH 7.4. GMQ opens only ASIC3 but no other ASICs at pH 7.4. GMQ can be used for neurological disease research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 5361-15-9. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-107757. | |
| GN25 | GN25 is a specific p53-Snail binding inhibitor with antitumor effects[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1227401-27-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117280. | |
| GN44028 | GN44028 is a potent and orally active hypoxia inducible factor (HIF)-1? inhibitor, with an IC50 of 14 nM. GN44028 inhibits hypoxia-induced HIF-1? transcriptional activity without suppressing HIF-1? mRNA expression, HIF-1? protein accumulation, or HIF-1?/HIF-1? heterodimerization. GN44028 can be used in the research of cancers[1][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1421448-26-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110266. | |
| GNE-049 | GNE-049 is a highly potent and selective CBP inhibitor with an IC50 of 1.1 nM in TR-FRET assay. GNE-049 also inhibits BRET and BRD4(1) with IC50s of 12 nM and 4200 nM, respectively[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1936421-41-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-108435. | |
| GNE-064 | GNE-064 (compound 5) is a selective, orally active and highly soluble inhibitor of SMARCA4, SMARCA2 and PBRM1 bromodomains 5. GNE-064 inhibits SMARCA4 with an IC50 of 0.035 ?M and inhibits SMARCA2 with an EC50 of 0.10 ?M. GNE-064 possess Kds with 0.01, 0.016, 0.018 and 0.049 ?M for SMARCA4, SMARCA2, PBRM1 bromodomains 5 and PBRM1 bromodomains 2, repectively. GNE-064 can be used as a chemical probe for the research of agent synthesis[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1997321-20-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-149026. | |
| GNE0877 | GNE0877 is a highly selective, orally active and brain-penetrant LRRK2 inhibitor with an IC50 of 3 nM and a Ki of 0.7 nM. GNE0877 can be used for the research of neuroscience[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1374828-69-9. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15796. | |
| GNE-140 racemate | GNE-140 racemate is a racemate mixture of (R)-GNE-140 and (S)-GNE-140. GNE-140 racemate is a potent lactate dehydrogenase A (LDHA) inhibitor [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1802977-61-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100742. | |
| GNE-272 | GNE-272 is a potent and selective CBP/EP300 inhibitor with IC50 values of 0.02, 0.03 and 13 ?M for CBP, EP300 and BRD4, respectively. GNE-272 is also a selective in vivo probe for CBP/EP300[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1936428-93-1. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100726. | |
| GNE 2861 | GNE 2861 is a PAK inhibitor that displays group II selectivity. GNE 2861 inhibits PAK4, PAK5 and PAK6 with IC50s of 7.5, 36, 126 nM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1394121-05-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12632. | |
| GNE-3511 | GNE-3511 is an orally active bioavailable and brain-penetrant dual leucine zipper kinase (DLK) inhibitor with a Ki of 0.5 nM. GNE-3511 can cross the blood-brain-barrier and can be used for the research of neurodegenerative diseases[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1496581-76-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12947. | |
| GNE-495 | GNE-495 is a potent and selective MAP4K4 inhibitor with an IC50 of 3.7 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1449277-10-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100343. | |
| GNE 5729 | GNE 5729 is a brain permeable positive allosteric modulator of NMDAR, with an EC50 of 37 nM for GluN2A, 4.7 and 9.5 ?M for GluN2C and GluN2D, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 2026635-66-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107409. | |
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