MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Lead carbonate(II) | Lead carbonate(II) is a kind of biochemical reagent. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 598-63-0. Pack Sizes: 25 g; 50 g. Product ID: HY-Y1877. |  |
| LEAP-2 | LEAP-2 is an antimicrobial peptide derived from human blood [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Human liver expressed antimicrobial peptide-2. CAS No. 1683582-94-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P5645. | |
| Lebrikizumab | Lebrikizumab (TNX-650) is an IgG4 humanized anti-interleukin-13 ( IL-13 ) mAb with anti-itch effects that specifically binds to IL-13 in a non-receptor binding domain and inhibits its function. Lebrikizumab inhibits the IL-13 driven Th2 inflammatory response and blocks the signaling of IL-4Rα/IL-13Rα1. Lebrikizumab can be used for the research of asthma, atopic dermatitis and neuroinflammatory diseases [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: TNX-650. CAS No. 953400-68-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99025. | |
| Lecithin | Lecithin is regarded as a safe, conventional phospholipid source. Phospholipids are reported to alter the fatty acid composition and microstructure of the membranes in animal cells. Uses: Scientific research. Group: Natural products. Alternative Names: Polyene phosphatidylcholine. CAS No. 8002-43-5. Pack Sizes: 100 mg; 500 mg. Product ID: HY-B2235. | |
| Ledaborbactam | Iedaborbactam (VNRX-5236), as a β-lactamase inhibitor (WO2015191907, Example 62), can be used for the research of bacterial infections [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: VNRX-5236. CAS No. 1842397-36-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-132823. | |
| (+)-Ledene | (+)-Ledene (Viridiflorene) is a terpenoid can be isolated from Melaleuca alternifolia [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Viridiflorene. CAS No. 21747-46-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-121472. | |
| Ledipasvir | Ledipasvir (GS-5885) is an inhibitor of the hepatitis C virus NS5A , with EC 50 s of 34 pM and 4 pM against genotype 1a and 1b replicon, respectively. Ledipasvir is also a SARS-CoV 3CL pro inhibitor with an IC 50 of 1.62 μM [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GS-5885. CAS No. 1256388-51-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15602. | |
| Ledipasvir D-tartrate | Ledipasvir D-tartrate is an inhibitor of the hepatitis C virus NS5A , with EC 50 values of 34 pM against GT1a and 4 pM against GT1b replicon. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GS-5885 D-tartrate. CAS No. 1502654-87-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15602B. | |
| Ledol | Ledol ((+)-Ledol) is an antifungal agent that can be isolated from the essential oil fractions of Rhododendron tomentosum. Ledol is also the expectorant and antitussive agent, which is simultaneously responsible for adverse reactions such as dizziness, nausea and vomiting [1]. Uses: Scientific research. Group: Natural products. Alternative Names: (+)-Ledol. CAS No. 577-27-5. Pack Sizes: 10 mg; 25 mg; 50 mg. Product ID: HY-121388. | |
| Leelamine | Leelamine is an orally active pyruvate dehydrogenase kinase ( PDK ) inhibitor with an IC 50 value of 9.5 μM, showing a blood glucose lowering effect in the diabetic mouse. Leelamine is also a weak agonist of cannabinoid receptors CB1 and CB2. Leelamine decreases mitotic activity, prostate-specific antigen expression and induces Apoptosis to cell death in cancer cells [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1446-61-3. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-W005629. | |
| Leelamine hydrochloride | Leelamine hydrochloride is a tricyclic diterpene molecule that is extracted from the bark of pine trees [1]. Leelamine hydrochloride is a cannabinoid receptor type 1 (CB1) agonist and a inhibitor of SREBP1-regulated fatty acid/lipid synthesis in prostate cancer cells that is not affected by androgen receptor status. Leelamine hydrochloride suppresses transcriptional activity of androgen receptor , which is known to regulate fatty acid synthesis [2,3]. Uses: Scientific research. Group: Natural products. CAS No. 16496-99-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110028. | |
| Lefamulin | Lefamulin (BC-3781) is an orally active antibiotic. Lefamulin inhibits protein synthesis by binding to the peptidyl transferase center of the 50S bacterial ribosome. Lefamulin has anti-inflammatory activity. Lefamulin can be used in the research of bacterial infections, such as bacterial pneumonia [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BC-3781. CAS No. 1061337-51-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16908. | |
| Lefamulin acetate | Lefamulin (BC-3781) acetate is an orally active antibiotic. Lefamulin acetate inhibits protein synthesis by binding to the peptidyl transferase center of the 50S bacterial ribosome. Lefamulin acetate has anti-inflammatory activity. Lefamulin acetate can be used in the research of bacterial infections, such as bacterial pneumonia [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BC-3781 acetate. CAS No. 1350636-82-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16908A. | |
| Leflunomide | Leflunomide is a pyrimidine synthesis inhibitor, inhibiting dihydroorotate dehydrogenase (DHODH), and acts as a disease-modifying antirheumatic agent. Uses: Scientific research. Group: Natural products. Alternative Names: HWA486; RS-34821; SU101. CAS No. 75706-12-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0083. | |
| Leishman's stain | Leishman's stain is an essential staining tool for for staining of the peripheral blood and bone marrow smears (displayed pale bluish-grey to deep blue under oil-immersion lens) [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 12627-53-1. Pack Sizes: 1 g. Product ID: HY-W250151. | |
| Lemildipine | Lemildipine is a new dihydropyridine calcium entry blocker. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NB-818; NPK-1886. CAS No. 94739-29-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19663. | |
| Lemzoparlimab | Lemzoparlimab (TJ011133; TJC4) is a humanized anti- CD47 IgG4 antibody. Lemzoparlimab has a strong anti-tumor activity [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: TJ011133; TJC4. CAS No. 2377483-71-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99026. | |
| Lenacapavir | Lenacapavir (GS-6207) is a HIV-1 capsid inhibitor. Lenacapavir shows anti-HIV activity with an EC 50 of 100 pM in MT-4 cells. Lenacapavir displays a mean EC 50 of 50 pM (20-160 pM) against 23 HIV-1 clinical isolates from different subtypes in peripheral blood mononuclear cells (PBMCs) [1]. Lenacapavir is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GS-6207. CAS No. 2189684-44-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-111964. | |
| Lenacil | Lenacil is a selective uracil substituted herbicide used for control of both annual grasses, broad leafed weeds and some perennial weeds in sugarcane, apples, alfalfa, peaches, peacans, peppermints ( Mentha piperita ) and sugar beets. Lenacil can inhibit photosynthesis [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2164-8-1. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116706. | |
| Lenalidomide | Lenalidomide (CC-5013), a derivative of Thalidomide, acts as molecular glue. Lenalidomide is an orally active immunomodulator. Lenalidomide (CC-5013) is a ligand of ubiquitin E3 ligase cereblon (CRBN) , and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide (CC-5013) specifically inhibits growth of mature B-cell lymphomas, including multiple myeloma, and induces IL-2 release from T cells [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CC-5013. CAS No. 191732-72-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-A0003. | |
| Lenalidomide-F | Lenalidomide-F is a E3 ligase ligand for LWY713. LWY713 is a PROTAC-class FLT3 degrader (DC 50 = 0.64 nM), which selectively induces FLT3 degradation via cereblon and proteasome-dependent pathways [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2359705-88-5. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-W039233. | |
| Lenalidomide-I | Lenalidomide-I (Compound 72), an analog of cereblon (CRBN) ligand Lenalidomide for E3 ubiquitin ligase, is used in the recruitment of CRBN protein. Lenalidomide-I can be connected to the ligand for protein by a linker to form PROTACs, such as the PROTAC BET degrader QCA570 (HY-112609) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2207541-30-6. Pack Sizes: 100 mg; 250 mg; 500 mg. Product ID: HY-131318. | |
| Lenalidomide (Standard) | Lenalidomide (Standard) is the analytical standard of Lenalidomide. This product is intended for research and analytical applications. Lenalidomide (CC-5013), a derivative of Thalidomide, acts as molecular glue. Lenalidomide is an orally active immunomodulator. Lenalidomide (CC-5013) is a ligand of ubiquitin E3 ligase cereblon (CRBN) , and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide (CC-5013) specifically inhibits growth of mature B-cell lymphomas, including multiple myeloma, and induces IL-2 release from T cells [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 191732-72-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0003R. | |
| Leniolisib | Leniolisib (CDZ173) is a potent and selective PI3Kδ inhibitor. Leniolisib has the potential for immunodeficiency disorders treatment. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CDZ173. CAS No. 1354690-24-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17635. | |
| Leniolisib phosphate | Leniolisib (CDZ173) phosphate is a potent and selective PI3Kδ inhibitor. Leniolisib phosphate has the potential for immunodeficiency disorders treatment. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CDZ173 phosphate. CAS No. 1354691-97-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17635A. | |
| Lentinan | Lentinan is an orally active biocompatible multifunctional polysaccharide with biological activities such as anti-inflammatory, antioxidant, immune regulation, anti-tumor, hypoglycemic, and lipid-lowering [1][4]. Uses: Scientific research. Group: Natural products. CAS No. 37339-90-5. Pack Sizes: 100 mg. Product ID: HY-N6653. | |
| Lenvatinib | Lenvatinib (E7080) is an oral, multi-targeted tyrosine kinase inhibitor that inhibits VEGFR1-3 , FGFR1-4 , PDGFR , KIT , and RET , shows potent antitumor activities [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: E7080. CAS No. 417716-92-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10981. | |
| Lenvatinib mesylate | Lenvatinib mesylate (E7080 mesylate), an oral, multi-targeted tyrosine kinase inhibitor that inhibits VEGFR1-3 , FGFR1-4 , PDGFR , KIT , and RET , shows potent antitumor activities [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: E7080 mesylate. CAS No. 857890-39-2. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-10981A. | |
| Lenvervimab | Lenvervimab (GC1102) is a IgG1-type recombinant human hepatitis B Immunoglobulin. Lenvervimab can be used for research of hepatitis B virus infection [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: GC1102. CAS No. 2055006-79-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99693. | |
| Lenzilumab | Lenzilumab (KB 003) is a human monoclonal antibody targeting CSF2/GM-CSF for COVID-19, chronic myelomonocytic leukemia (CMML) and juvenile myelomonocytic leukemia (JMML) studies [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: KB 003. CAS No. 1229575-09-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99207. | |
| Leonurine | Leonurine is an alkaloid isolated from Leonurus artemisia , with anti-oxidative and anti-inflammatory. Uses: Scientific research. Group: Natural products. Alternative Names: SCM-198. CAS No. 24697-74-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0741. | |
| Leonurine hydrochloride | Leonurine hydrochloride is an alkaloid isolated from Leonurus artemisia , with anti-oxidative and anti-inflammatory. Uses: Scientific research. Group: Natural products. Alternative Names: SCM-198 hydrochloride. CAS No. 24735-18-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0741A. | |
| Leptomycin B | Leptomycin B (CI 940; LMB) is a potent inhibitor of the nuclear export of proteins. Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue. Leptomycin B is a potent antifungal antibiotic blocking the eukaryotic cell cycle [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CI 940; LMB. CAS No. 87081-35-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-16909. | |
| Leptospermone | Leptospermone is a competitive, reversible inhibitor for p-Hydroxyphenylpyruvate dioxygenase ( HPPD ), with an IC 50 of 12.1 μM. Leptospermone exhibits herbicidal activity for its bleaching effect [1]. Uses: Scientific research. Group: Natural products. CAS No. 567-75-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-114991. | |
| Lercanidipine | Lercanidipine is a third-generation, lipophilic, brain-penetrant, vascular-selective and orally active dihydropyridine- calcium channel blocker with a pIC 50 of 7.74 (converts from μM). Lercanidipine has long lasting antihypertensive action as well as reno- and neuro-protective effect. Lercanidipine also shows anti-oxidant, anti-inflammatory and anti-apoptotic properties. Lercanidipine can be used in cardiovascular and neurological research [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 100427-26-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-B0612. | |
| Lercanidipine-d3 hydrochloride | Lercanidipine-d 3 (hydrochloride) is the deuterium labeled Lercanidipine. Lercanidipine is a lipophilic third-generation dihydropyridine-calcium channel blocker (DHP-CCB). Lercanidipine has long lasting antihypertensive action and reno-protective effect[1][2][3]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 1189954-18-4. Pack Sizes: 1 mg. Product ID: HY-B0612DS1. | |
| Lercanidipine hydrochloride | Lercanidipine is a third-generation, lipophilic, brain-penetrant, vascular-selective and orally active dihydropyridine- calcium channel blocker with a pIC 50 of 7.74 (converts from μM). Lercanidipine has long lasting antihypertensive action as well as reno- and neuro-protective effect. Lercanidipine also shows anti-oxidant, anti-inflammatory and anti-apoptotic properties. Lercanidipine can be used in cardiovascular and neurological research [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 132866-11-6. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-B0612A. | |
| Leriglitazone | Leriglitazone (MIN-102; Hydroxypioglitazone) is an orally active and a BBB-penatrable PPARγ agonist with an EC 50 of 9 μM. Leriglitazone, as a regulator of mitochondrial function, has neuroprotective, anti-inflammatory and antioxidant effects. Leriglitazone can be used in the study of neuroinflammatory and neurodegenerative diseases [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MIN-102; Hydroxypioglitazone. CAS No. 146062-44-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-117727. | |
| Leriglitazone hydrochloride | Leriglitazone (MIN-102; Hydroxypioglitazone) hydrochloride is an orally active and a BBB-penatrable PPARγ agonist with an EC 50 of 9 μM. Leriglitazone hydrochloride, as a regulator of mitochondrial function, has neuroprotective, anti-inflammatory and antioxidant effects. Leriglitazone hydrochloride can be used in the study of neuroinflammatory and neurodegenerative diseases [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MIN-102 hydrochloride; Hydroxypioglitazone hydrochloride. CAS No. 146062-46-6. Pack Sizes: 10 mM * 1 mL; 5 mg. Product ID: HY-117727A. | |
| Lerisetron | Lerisetron is a potent 5-HT 3 antagonists and possess high-affinity binding for the 5-HT 3 receptors with pK i value of 9.2. Lerisetron has a potent ability to inhibit the 5-HT-evoked reflex bradycardia in urethane-anesthetized rats [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 143257-98-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-105090. | |
| Leritrelvir | Leritrelvir (RAY1216) is an orally active SARS-CoV-2 main protease slow-tight inhibitor with a K i of 8.6 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RAY1216. CAS No. 2923310-64-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-153121. | |
| Lerociclib | Lerociclib (G1T38) is a potent and selective inhibitor of CDK4/6 , with IC 50 s of 1 nM, 2 nM for CDK4/CyclinD1 and CDK6/CyclinD3, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: G1T38. CAS No. 1628256-23-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-112272. | |
| Lerociclib dihydrochloride | Lerociclib dihydrochloride (G1T38 dihydrochloride) is a potent and selective inhibitor of CDK4 / CDK6 , with IC 50 s of 1 nM and 2 nM for CDK4 / CyclinD1 and CDK6 / CyclinD3 , respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: G1T38 dihydrochloride. CAS No. 2097938-59-3. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-112272A. | |
| Leronlimab | Leronlimab (PRO 140) is a humanized IgG4 anti-CCR5 monoclonal antibody. Leronlimab inhibits CCR5-mediated HIV-1 viral and lung metastasis in mouse tumor models. Leronlimab can be used for the research of HIV nonalcoholic steatohepatitis (NASH) and cancer [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: PRO 140. CAS No. 674782-26-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99697. | |
| Lersivirine | Lersivirine (UK-453061) is potent and selective non-nucleoside reverse transcription inhibitor (NNRTI; IC 50 =119 nM) with excellent efficacy against NNRTI-resistant viruses. Lersivirine exhibits potent antiretroviral activity against wild-type HIV virus and clinically relevant NNRTI-resistant strains [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: UK-453061. CAS No. 473921-12-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-14267. | |
| Lesinurad | Lesinurad is a URAT1 and OAT inhibitor, is determined to be a substrate for the kidney transporters OAT1 and OAT3 with K m values of 0.85 and 2 μM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RDEA594. CAS No. 878672-00-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15258. | |
| Lesinurad sodium | Lesinurad sodium is a URAT1 and OAT inhibitor, is determined to be a substrate for the kidney transporters OAT1 and OAT3 with K m values of 0.85 and 2 μM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RDEA-594 sodium. CAS No. 1151516-14-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-15258A. | |
| Lesogaberan hydrochloride | Lesogaberan (AZD-3355) hydrochloride is a potent and selective GABA B receptor agonist with an EC 50 of 8.6 nM for human recombinant GABA B receptor. The affinity ( K i s) of Lesogaberan hydrochloride for rat GABA B and GABA A receptors, as measured by displacement of [ 3 H]GABA binding in brain membranes: 5.1 nM and 1.4 μM, respectively. Lesogaberan hydrochloride inhibits transient lower esophageal sphincter relaxation through a peripheral mode of action [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AZD-3355 hydrochloride. CAS No. 2925644-17-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-10061B. | |
| Lesopitron dihydrochloride | Lesopitron dihydrochloride is a full and selective 5-HT 1A receptor agonist with IC 50 of 125 nM in rat hippocampal membranes. Uses: Scientific research. Group: Signaling pathways. Alternative Names: E4424. CAS No. 132449-89-9. Pack Sizes: 1 mg. Product ID: HY-101609. | |
| Lestaurtinib | Lestaurtinib (CEP-701) is an orally active and selective RPTKs (receptor protein tyrosine kinase) inhibitor, competitively inhibits ATP binding to the TrkA/B/C domain. Lestaurtinib inhibits RPTKs phosphorylation, with IC 50 s of 2, 25 and 0.9 nM for FLT3 , TrkA and JAK2 , respectively. Lestaurtinib induces apoptosis and cycle arrest, also can inhibit growth of tumor [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CEP-701; KT-5555. CAS No. 111358-88-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-50867. | |
| LETC | LETC is an orally active α-synuclein (α-Syn) aggregation inhibitor with an EC 50 of 66 nM in transfected DH60.21 neuroblastoma cells. LETC can cross the blood-brain barrier. LETC can be used for the study of synucleinopathies [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 951131-13-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-163739. | |
| Leteprinim potassium | Leteprinim potassium (AIT-082), a purine analog, is a neuroprotective agent and cognitive enhancer. Leteprinim potassium is a hypoxanthine derivative neurotrophic agent. Leteprinim potassium can induce brain-derived neurotrophic factor (BDNF) mRNA production following spinal cord lesions, and nerve growth factor (NGF) mRNA production in basal forebrain. Leteprinim potassium reduces glutamate toxicity in cultured hippocampal neurons. Leteprinim potassium increases heme-oxygenase 1 and 2 mRNA levels that play role in cellular defense against reactive oxygen species [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AIT-082. CAS No. 192564-13-9. Pack Sizes: 5 mg. Product ID: HY-120251A. | |
| Letermovir | Letermovir (AIC246) is a potent inhibitor of CMV , which targets the viral terminase complex and remains active against virus resistant to DNA polymerase inhibitors. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AIC246; MK-8228. CAS No. 917389-32-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15233. | |
| L-Ethionine | L-Ethionine (L-ETH) is aamino acids and their derivatives. Uses: Scientific research. Group: Peptides. Alternative Names: L-ETH. CAS No. 13073-35-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W017200. | |
| Letolizumab | Letolizumab (BMS-986004) is a monoclonal antibody targeting CD40L , which is produced to express mutant IgG1 lacking effector function, including Fc binding and complement fixation. Letolizumab reduces rejection, thromboembolism and prolongs the survival time [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BMS-986004. CAS No. 1450981-87-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99701. | |
| Letosteine | Letosteine is an orally active, potent and safe expectorant. Letosteine has the effect of scavenging reactive oxygen species (ROS). Letosteine dissolves bronchial mucus and reduces respiratory inflammation symptoms, and restores gas exchanges and natural defense mechanisms in the lung. Letosteine can be used for acute or chronic respiratory diseases (such as bronchopneumopathies) research [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 53943-88-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107355. | |
| Letrozole | Letrozole (CGS 20267) is a potent, selective, reversible and orally active non-steroidal inhibitor of aromatase , with an IC 50 of 11.5 nM. Letrozole selective inhibits estrogen biosynthesis, and can be used for the research of breast cancer [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: CGS 20267. CAS No. 112809-51-5. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg. Product ID: HY-14248. | |
| [Leu31,Pro34]-Neuropeptide Y (porcine) | [Leu31,Pro34]- Neuropeptide Y (porcine), a Neuropeptide Y (NPY) analog, is a selective NPY Y1 receptor agonist. [Leu31,Pro34]- Neuropeptide Y (porcine) exhibits anxiolytic effects [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 125580-28-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P0208. | |
| [Leu5]-Enkephalin | [Leu5]-Enkephalin is a pentapeptide with morphine like properties. [Leu5]-Enkephalin is a five amino acid endogenous peptide that acts as an agonist at opioid receptors. Uses: Scientific research. Group: Peptides. Alternative Names: Leu-enkephalin; Leucine enkephalin; Leucyl-enkephalin. CAS No. 58822-25-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P0288. | |
| Leucic acid | Leucic acid is an amino acid metabolite [1]. Uses: Scientific research. Group: Peptides. Alternative Names: α-Hydroxyisocaproic acid. CAS No. 498-36-2. Pack Sizes: 10 mM * 1 mL; 250 mg; 500 mg; 1 g. Product ID: HY-30216A. | |
| (±)-Leucine | (±)-Leucine (DL-Leucine), an isomer of Leucine, chemosterilant and dietary additive. (±)-Leucine inhibits growth of Escherichia coli HfrH by 92.08% [1]. Uses: Scientific research. Group: Natural products. Alternative Names: DL-Leucine; (RS)-Leucine. CAS No. 328-39-2. Pack Sizes: 10 mM * 1 mL; 500 mg; 5 g. Product ID: HY-B1674. | |
| (±)-Leucine-d10 | (±)-Leucine-d 10 is the deuterium labeled (±)-Leucine. (±)-Leucine (DL-Leucine), an isomer of Leucine, chemosterilant and dietary additive. (±)-Leucine inhibits growth of Escherichia coli HfrH by 92.08%[1]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: DL-Leucine-d10; (RS)-Leucine-d10. CAS No. 29909-01-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-B1674S. | |
| Leucine dehydrogenase, Microorganism | Leucine dehydrogenase, Microorganism (EC 1.4.1.9) can be purified from Bacillus spheroides. Leucine dehydrogenase catalyzed the oxidative deamination of L-leucine, L-valine, L-isoleucine, L-norvaline, L-alpha-aminobutyrate, and L-norleucine, and the reductive amination of their keto analogues [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LDH, EC 1.4.1.9. CAS No. 9082-71-7. Pack Sizes: 1 KU; 100 U; 200 U. Product ID: HY-P2768. | |
| Leucocrystal violet | Leucocrystal violet is a triphenylmethane dye which can be used to detect antimony in environmental and biological samples using spectrophotometric techniques. Uses: Scientific research. Group: Fluorescent dye. CAS No. 603-48-5. Pack Sizes: 1 g; 5 g; 10 g. Product ID: HY-D0233. | |
| (+)-Leucocyanidin | (+)-Leucocyanidin is the isoform of Leucocyanidin (HY-119580), is an active anti-ulcerogenic ingredient was extracted from Litchi Chinensis. Leucocyanidin demonstrates a significant protective effect against Aspirin-induced erosions in rat models [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 2,3-trans-3,4-trans-Leucocyanidin; 3,4-trans-Leucocyanidin; (2R,3S,4R)-Leucocyanidin. CAS No. 69256-15-1. Pack Sizes: 1 mg. Product ID: HY-119580B. | |
| Leucomethylene blue mesylate | Leucomethylene blue (TRx0237) mesylate, an orally active second-generation tau protein aggregation inhibitor (K i of 0.12 μM), could be used for the study of Alzheimer's Disease. Leucomethylene blue mesylate is a common reduced form of Methylene Blue, Methylene Blue is a member of the thiazine class of dyes [1] [2] [3]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: TRx0237 mesylate; Methylene blue leuco base mesylate. CAS No. 1236208-20-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19948. | |
| Leucyl-phenylalanine | Leucyl-phenylalanine belongs to the class of organic compounds known as dipeptides. Uses: Scientific research. Group: Natural products. CAS No. 3063-5-6. Pack Sizes: 10 mM * 1 mL; 50 mg. Product ID: HY-113278. | |
| Leukotriene B4 | Leukotriene B4 (LTB4) is known as one of the most potent chemoattractants and activators of leukocytes and is involved in inflammatory diseases. Leukotriene B4 is also an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: LTB4; 5(S),12(R)-DiHETE. CAS No. 71160-24-2. Pack Sizes: 25 μg (297.2 μM * 250 μL in Ethanol). Product ID: HY-107608. | |
| Leukotriene C4 | Leukotriene C4 is a eicosanoid lipid mediator and produced by immune cells during type 2 inflammation. Leukotriene C4 can mediate inflammation,allergy, bronchoconstriction, and vascular leakage [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 72025-60-6. Pack Sizes: 25 μg (159.8 μM * 250 μL in Ethanol). Product ID: HY-113446. | |
| Leukotriene D4 | Leukotriene D4 is a potent bronchoconstrictor. Leukotriene D4 has the potential for the research of asthma. Leukotriene D4 induces edema and increases capillary permeability [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 73836-78-9. Pack Sizes: 10 μg (201.34 μM * 100 μL in Ethanol); 50 μg (201.34 μM * 500 μL in Ethanol). Product ID: HY-113456. | |
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