MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Linalool | Linalool is a natural monoterpene which is a competitive NMDA receptor antagonist. Linalool is orally active and crosses the blood-brain barrier. Linalool has anticancer, antibacterial, anti-inflammatory, neuroprotective, anxiolytic, antidepressant, anti-stress, cardioprotective, hepatoprotective, nephroprotective and pulmonary protective activities [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. CAS No. 78-70-6. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-N0368. |  |
| Linalool oxide | Linalool oxide is a secondary metabolite in elongating wheat plants with antinociceptive and anticonvulsant effects. Linalool oxide shows anxiolytic activity [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 60047-17-8. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-N9502. | |
| Linalyl acetate | Linalyl acetate is the principal components of many plant essential oils with potentially anti-inflammatory activity [1]. Uses: Scientific research. Group: Natural products. CAS No. 115-95-7. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-N6948. | |
| Linamarin | Linamarin, a natural compound, possesses anticancer activity [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Phaseolunatin. CAS No. 554-35-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-123114. | |
| Linaprazan | Linaprazan (AZD0865) can inhibit H+,K+ -ATPase in the stomach through K+ competitive binding, ( IC 50 : 1.0 ± 0.2 μM), it has a strong inhibitory effect on acid. Linaprazan (AZD0865) can be used for research on reflux esophagitis with oral activity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AZD0865. CAS No. 248919-64-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100412. | |
| Linaprazan glurate | Linaprazan glurate inhibits exogenously or endogenously stimulated gastric acid secretion. Linaprazan glurate exhibits several advantageous properties, such as fast onset, high in vivo potency and/or long duration of action. Linaprazan glurate is useful in the research of gastrointestinal inflammatory diseases and peptic ulcer diseases (extracted from patent WO2010063876A1) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: X842. CAS No. 1228559-81-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145578. | |
| Linarin | Linarin (Buddleoside) is an orally active and selective inhibitor of acetylcholinesterase ( AChE ). Linarin has many activities, such as anti-inflammatory, antioxidant, sleep aid and sedation, bone differentiation, anti-tumor, antibacterial and antiviral. Linarin can be used to study diseases such as the nervous system, osteoporosis and cancer [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Buddleoside; Linarine. CAS No. 480-36-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 20 mg. Product ID: HY-N0528. | |
| Linavonkibart | Linavonkibart (SRK 181) is a high-affinity, fully human antibody that selectively binds to latent TGFβ1 and inhibits its activation. Linavonkibart plays an important role in cancer [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: SRK-181. CAS No. 2640981-30-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990069. | |
| Lincomycin | Lincomycin, a lincosamide antibiotic, is an antimicrobial agent used for the research of Gram-positive bacteria infections [1]. Uses: Scientific research. Group: Natural products. Alternative Names: U-10149. CAS No. 154-21-2. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-117660. | |
| Lincomycin hydrochloride | Lincomycin Hydrochloride(U10149A) is an antibiotic produced by Streptomyces lincolnensis var. Uses: Scientific research. Group: Natural products. Alternative Names: U10149A. CAS No. 859-18-7. Pack Sizes: 100 mg. Product ID: HY-B0417A. | |
| Lincomycin hydrochloride monohydrate | Lincomycin hydrochloride monohydrate is a narrow-spectrum antibiotic, has similar effects to erythromycin, which has a good effect on gram-positive coccus, mainly used to inhibit the synthesis of bacterial cell protein [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 7179-49-9. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-B1358. | |
| Linerixibat | Linerixibat (GSK2330672) is a highly potent, nonabsorbable and orally active apical sodium-dependent bile acid transporter (ASBT) inhibitor with an IC 50 of 42 nM human ASBT. Linerixibat can be used as lipid-lowering agent. Linerixibat has the potential for type 2 diabetes and Primary Biliary Cholangitis treatment [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GSK2330672. CAS No. 1345982-69-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16643. | |
| Linezolid | Linezolid (PNU-100766) is the first member of the class of oxazolidinone synthetic antibiotic. Linezolid acts by inhibiting the initiation of bacterial protein synthesis. Linezolid is used for the treatment of serious infections caused by Gram-positive bacteria that are resistant to several other antibiotics [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PNU-100766. CAS No. 165800-03-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10394. | |
| Linezolid-d3 | Linezolid-d 3 is a deuterium labeled Linezolid (PNU-100766). Linezolid is a synthetic antibiotic that acts by inhibiting the initiation of bacterial protein synthesis[1]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: PNU-100766-d3. CAS No. 1127120-38-0. Pack Sizes: 1 mg. Product ID: HY-10394S. | |
| Linezolid (Standard) | Linezolid (Standard) is the analytical standard of Linezolid. This product is intended for research and analytical applications. Linezolid (PNU-100766) is the first member of the class of oxazolidinone synthetic antibiotic. Linezolid acts by inhibiting the initiation of bacterial protein synthesis. Linezolid is used for the treatment of serious infections caused by Gram-positive bacteria that are resistant to several other antibiotics [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PNU-100766 (Standard). CAS No. 165800-03-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10394R. | |
| Linifanib | Linifanib (ABT-869) is a potent and orally active multi-target inhibitor of VEGFR and PDGFR family with IC 50 s of 4, 3, 66, and 4 nM for KDR, FLT1, PDGFRβ, and FLT3, respectively. Linifanib shows prominent antitumor activity. Linifanib has much less activity against unrelated RTKs, soluble tyrosine kinases, or serine/threonine kinases. Linifanib is a specific miR-10b inhibitor that blocks miR-10b biogenesis [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABT-869; AL-39324. CAS No. 796967-16-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-50751. | |
| Linoleate sodium | Linoleate sodium is an orally active IL8 regulator via the JNK and NF-κB pathway. Linoleate sodium can change the composition of fatty acids and the production of metabolites in cells. Linoleate sodium has anti-inflammatory, immune-regulating, and tumor cell growth-affecting activities [1] [2] [3] [4] [5] [6] [7] [8] [9]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 822-17-3. Pack Sizes: 25 mg; 50 mg. Product ID: HY-W011398. | |
| Linoleic acid | Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 60-33-3. Pack Sizes: 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-N0729. | |
| Linoleic acid-13C18 | Linoleic acid- 13 C 18 is the 13 C labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism [1][2]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 287111-25-5. Pack Sizes: 500 μg; 1 mg. Product ID: HY-N0729S2. | |
| Linolelaidic acid | Linolelaidic acid (Linoelaidic acid) is an omega-6 trans fatty acid (TFA) that is an essential nutrient with oral activity. Linolelaidic acid can be added to enteral nutrition (oral), parenteral nutrition (intravenous), and infant formula. Linolelaidic acid has anti-inflammatory and anti-parasitic (( Parasite )) activities, and can induce Apoptosis. Linolelaidic acid is useful for research in infections [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Linoelaidic acid. CAS No. 506-21-8. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-W071746. | |
| Linoleoyl ethanolamide | Linoleoyl ethanolamide (Linoleic acid monoethanolamide) is classified as a fatty acid ethanolamide. Linoleoyl ethanolamide only weakly binds G-protein-coupled cannabinoid receptors of type-1 (CB1) and CB2 receptors, and inhibits the binding of [3H] CP-55,940 with K i s of 10 and 25 μM, respectively. Linoleoyl ethanolamide is 4-fold less potent than anandamide at causing catalepsy in mice and it does not prolong sleep time [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Linoleic acid monoethanolamide. CAS No. 68171-52-8. Pack Sizes: 5 mg. Product ID: HY-113421. | |
| Linoleyl alcohol | Linoleyl alcohol, a structural analog of Linoleic acid with no a-carboxyl group, is a fatty alcohol [1]. Uses: Scientific research. Group: Natural products. CAS No. 506-43-4. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-W005627. | |
| Linoleyl carnitine | Linoleyl carnitine is an acylcarnitine used to study long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency and fatty acid oxidation disorders in fibroblasts [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 36816-10-1. Pack Sizes: 1 mg. Product ID: HY-113256. | |
| Linopirdine | Linopirdine (DuP 996) is an orally active, selective M-type K + current (IM; Kv7; KCNQ Channels) inhibitor with an IC 50 of 2.4 μM. Linopirdine is a TRPV1 agonist. Linopirdine, a putative cognition enhancing agent, increases acetylcholine release in rat brain tissue [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DuP 996. CAS No. 105431-72-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W020468. | |
| Linperlisib | Linperlisib (YY-20394) is a potent, orally bioavailable and selective inhibitor of PI3Kδ extracted from patent WO 2015055071 A1, compound 10; has an IC 50 of 6.4 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: YY-20394. CAS No. 1702816-75-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-102031. | |
| Linrodostat | Linrodostat (BMS-986205) is a selective and irreversible indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor with an IC 50 value of 1.1 nM in IDO1 -HEK293 cells. Linrodostat is well tolerated with potent pharmacodynamic activity in advanced cancers [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-986205; ONO-7701. CAS No. 1923833-60-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101560. | |
| Linsidomine hydrochloride | SIN-1 (chloride) is the active metabolite of molsidomine. SIN-1 (chloride) exhibits potent vasorelaxant effect and inhibition of platelet aggregation [1]. SIN-1 (chloride) decreases myocardial necrosis and reperfusion-induced endothelial dysfunction in models of myocardial ischemia-reperfusion [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SIN-1 chloride. CAS No. 16142-27-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101200. | |
| Linsitinib | Linsitinib (OSI-906) is a potent, selective and orally bioavailable dual inhibitor of the IGF-1 receptor and insulin receptor (IR) with IC 50 s of 35 and 75 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: OSI-906. CAS No. 867160-71-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10191. | |
| Lintuzumab | Lintuzumab (HUM-195) is an anti- CD33 humanized monoclonal antibody. Lintuzumab reduces the production of TNFα-induced pro-inflammatory cytokines and chemokines by AML cells. Lintuzumab promotes tumor cell killing through antibody-dependent cellular cytotoxicity (ADCC) and phagocytosis (ADCP) activities against MDR and MDR+ AML cell lines and primary AML patient samples. Lintuzumab enhances survival and reduces tumor burden in mice [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: HuM-195. CAS No. 166089-32-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9983. | |
| Linuron | Linuron is a phenylurea herbicide that is widely used to control the growth of grass and weeds in various agriculture crops and in orchards. Linuron is a photosystem II inhibitor. Linuron is also a competitive androgen receptor (AR) antagonist with a K i of 100 μM. Linuron shows reproductive toxicity in animals that acts as an endocrine disruptor [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 330-55-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-B1866. | |
| Linvencorvir | Linvencorvir is an antiviral agent [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RG7907. CAS No. 1808248-05-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145579. | |
| Linvoseltamab | Linvoseltamab is a bispecific antibody targeting to both BCMA ( TNFRSF17 ) and CD3 epsilon. Linvoseltamab shows safety profile and encouraging efficacy in relapsed/refractory multiple myeloma (RRMM) models [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: REGN5458. CAS No. 2408319-25-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P9989. | |
| Linzagolix | Linzagolix (KLH-2109; OBE-2109) is a potent, non-peptide, and orally active GnRH antagonist. Linzagolix can be used for uterine fibroids, endometriosis, adenomyosis research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KLH-2109; OBE-2109. CAS No. 935283-04-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109093. | |
| Liothyronine | Liothyronine is an active form of thyroid hormone. Liothyronine binds to thyroid hormone receptors TRα and TRβ with K i s of 2.33 and 2.29 nM for hTRα and hTRβ, respectively. Liothyronine also binds to PVR and blocks the interaction of TIGIT/PVR [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Triiodothyronine; 3,3',5-Triiodo-L-thyronine; T3. CAS No. 6893-2-3. Pack Sizes: 100 mg; 500 mg; 1 g. Product ID: HY-A0070A. | |
| Liothyronine sodium | Liothyronine sodium is an active form of thyroid hormone. Liothyronine sodium is a potent thyroid hormone receptors TRα and TRβ agonist with K i s of 2.33 nM for hTRα and hTRβ, respectively [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Triiodothyronine sodium; 3,3',5-Triiodo-L-thyronine sodium; T3 sodium. CAS No. 55-06-1. Pack Sizes: 100 mg; 500 mg. Product ID: HY-A0070. | |
| Liothyronine sodium hydrate | Liothyronine sodium hydrate is an active form of thyroid hormone. Liothyronine sodium hydrate is a potent thyroid hormone receptors TRα and TRβ agonist with K i s of 2.33 nM for hTRα and hTRβ, respectively [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Triiodothyronine sodium hydrate; 3,3',5-Triiodo-L-thyronine sodium hydrate; T3 sodium hydrate. CAS No. 345957-19-9. Pack Sizes: 100 mg. Product ID: HY-A0070B. | |
| Lipid 5 | Lipid 5 is an amino lipid that affords efficient mRNA delivery in rodent and primate models. Lipid 5 shows optimal pharmacokinetics and non-toxic side effects [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 2089251-33-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138171. | |
| Lipoamide | Lipoamide ((±)-α-Lipoamide) is a monocarboxylic acid derivative of a neutral amide, formed by the condensation of the carboxyl group of lipoic acid and ammonia. Lipoamide protects against oxidative stress-mediated neuronal cell damage and also acts as a coenzyme to transfer acetyl groups and hydrogen during pyruvate deacylation. Lipoamide also stimulates mitochondrial biogenesis in adipocytes through the endothelial NO synthase-cGMP-protein kinase G signaling pathway [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: (±)-α-Lipoamide; DL-Lipoamide; DL-6,8-Thioctamide. CAS No. 940-69-2. Pack Sizes: 100 mg; 500 mg. Product ID: HY-B1142. | |
| Lipoic acid | Lipoic acid ((R)-(+)-α-Lipoic acid) is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. (R)-(+)-α-Lipoic acid is more effective than racemic Lipoic acid. Uses: Scientific research. Group: Natural products. Alternative Names: (R)-(+)-α-Lipoic acid; R-(+)-Thioctic acid. CAS No. 1200-22-2. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-18733. | |
| Lipoteichoic acid | Lipoteichoic acid is an orally effect anti-inflammatory and antitumor agent. Lipoteichoic acid is a crucial immune molecule in Gram-positive bacteria that activates the complement system by inducing C3 and inhibiting CD55. Lipoteichoic acid regulates macrophage autophagy through the PI3K/Akt/mTOR pathway. Lipoteichoic acid induces lung damage in mice. Lipoteichoic acid inhibits the production of melanin [1] [2] [3] [4] [5] [6] [7]. Uses: Scientific research. Group: Natural products. CAS No. 56411-57-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N9481. | |
| Lipoxin A4 | Lipoxin A4 (LXA4), an endogenous lipoxygenase-derived eicosanoid mediator, has potent dual pro-resolving and anti-inflammatory properties [1]. Lipoxin A4 inhibits proliferation and inflammatory cytokine/chemokine production of human epidermal keratinocytes (NHEKs) associated with the ERK1/2 and NF-kB pathways [2]. Lipoxin A4 inhibits serum amyloid A (SAA)-mediated IL-8 release with an IC 50 value of 25.74 nM [3]. Uses: Scientific research. Group: Natural products. Alternative Names: LXA4. CAS No. 89663-86-5. Pack Sizes: 25 μg (283.71 μM * 250 μL in Ethanol). Product ID: HY-113509. | |
| Lipstatin | Lipstatin is a pancreatic lipase inhibitor ( IC 50 =0.14 μM), whose structure is closely related to the known inhibitor, Esterastin. Lipstatin inhibits the absorption of triglycerides without affecting the absorption of oleic acid. Lipstatin has no inhibitory effects on other pancreatic enzymes, such as phospholipase A2 and trypsin (<200 μM) [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 96829-59-3. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N2330. | |
| Liquiritigenin | Liquiritigenin, a flavanone isolated from Glycyrrhiza uralensis , is a highly selective estrogen receptor β ( ERβ ) agonist with an EC 50 of 36.5 nM for activation of the ERE tk-Luc. Uses: Scientific research. Group: Natural products. Alternative Names: 4',7-Dihydroxyflavanone. CAS No. 578-86-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-N0377. | |
| (±)-Liquiritigenin | (±)-Liquiritigenin ((±)-4',7-Dihydroxyflavanone) is isolated from Angelica keiskei , a hardy perennial herb of the Umbelliferae family. (±)-Liquiritigenin promotes cell proliferation, has cytoprotective activity and reduces cytotoxicity, and also has antioxidant stress effects [1]. Uses: Scientific research. Group: Natural products. Alternative Names: (±)-4',7-Dihydroxyflavanone. CAS No. 69097-97-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N0377A. | |
| Liquiritin | Liquiritin, a flavonoid isolated from Glycyrrhiza uralensis , is a potent and competitive AKR1C1 inhibitor with IC 50 s of 0.62 μM, 0.61 μM, and 3.72μM for AKR1C1, AKR1C2 and AKR1C3, respectively. Liquiritin efficiently inhibits progesterone metabolism mediated by AKR1C1 in vivo [1]. Liquiritin acts as an antioxidant and has neuroprotective, anti-cancer and anti-inflammatory activity [2]. Uses: Scientific research. Group: Natural products. CAS No. 551-15-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0376. | |
| Lirafugratinib | Lirafugratinib (RLY-4008) is an orally active, irreversible and highly selective FGFR2 inhibitor with an IC 50 of 3 nM. Lirafugratinib covalently binds to Cys491. Lirafugratinib targets FGFR2 primary alterations and resistance mutations and induces tumor regression while sparing other FGFRs [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RLY-4008. CAS No. 2549174-42-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147250. | |
| Lirafugratinib hydrochloride | Lirafugratinib (RLY-4008) hydrochloride is an orally active, irreversible and highly selective FGFR2 inhibitor with an IC 50 of 3 nM. Lirafugratinib hydrochloride covalently binds to Cys491. Lirafugratinib hydrochloride targets FGFR2 primary alterations and resistance mutations and induces tumor regression while sparing other FGFRs [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RLY-4008 hydrochloride. CAS No. 2688040-45-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147250A. | |
| Liraglutide | Liraglutide is a glucagon-like peptide-1 ( GLP-1 ) receptor agonist used clinically to treat type 2 diabetes mellitus. Uses: Scientific research. Group: Peptides. CAS No. 204656-20-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0014. | |
| Liranaftate | Liranaftate (Piritetrate) is a squalene epoxidase inhibitor with anti-fungicidal activities. Liranaftate can be used for the research of dermatophytes. Liranaftate also suppresses fungal element-promoted production of IL-8 and experimental inflammation [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Piritetrate; M-732. CAS No. 88678-31-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0348. | |
| Lirentelimab | Lirentelimab (AK002) is a humanized IgG1 monoclonal antibody that targets sialic acid-binding Ig-like lectin 8 ( SIGLEC8 ). Lirentelimab induces cell apoptosis of IL-5-activated eosinophils and inhibits IgE-mediated mast cell activation. Lirentelimab can be used for the research of eosinophilic gastritis and duodenitis [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: AK002; Antolimab. CAS No. 2283348-97-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99371. | |
| Lirilumab | Lirilumab (IPH2102) is an anti-KIR monoclonal antibody, and shows antitumor activity. Lirilumab can be used in Leukemia, squamous cell carcinoma of the head and neck (SCCHN) research [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: IPH2102. CAS No. 1000676-41-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99208. | |
| Liriodenine | Liriodenine (Spermatheridine; VLT045) is an aporphine alkaloid isolated from the plant Mitrephora sirikitiae and has anti-cancer activities [1]. Liriodenine induces cell apoptosis , activates the intrinsic pathway by induction of caspase-3 and caspase-9 [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Spermatheridine; VLT045. CAS No. 475-75-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N3376. | |
| Liriopesides B | Liriopesides B (Nolinospiroside F) is a steroidal saponin isolated from Ophiopogon japonicas. Liriopesides B has anti-oxidative and anti-aging effects [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Nolinospiroside F. CAS No. 87425-34-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N5135. | |
| Lisaftoclax | Lisaftoclax (compound 6) is a dual Bcl-2 and Bcl-xl inhibitor with anti-tumor activity, extracted from patent WO2018027097A1. Lisaftoclax exhibits IC 50 values of 2 nM and 5.9 nM for Bcl-2 and Bcl-xl, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: APG-2575; Bcl-2/Bcl-xl inhibitor 1. CAS No. 2180923-05-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129179. | |
| Lisavanbulin | Lisavanbulin (BAL-101553) is the prodrug of the microtubule targeting agent Avanbulin (BAL 27862) (HY-106008). Lisavanbulin exhibits antitumor activity, especially in tumors that express high levels of end-binding protein 1 [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAL-101553. CAS No. 1263384-43-5. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-19916. | |
| Lisavanbulin dihydrochloride | Lisavanbulin (BAL-101553) dihydrochloride is the prodrug of the microtubule targeting agent Avanbulin (BAL 27862) (HY-106008). Lisavanbulin dihydrochloride exhibits antitumor activity, especially in tumors that express high levels of end-binding protein 1 [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAL-101553 dihydrochloride. CAS No. 1387574-54-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-19916A. | |
| Lisinopril | Lisinopril (MK-521) is angiotensin-converting enzyme inhibitor, used in treatment of hypertension, congestive heart failure, and heart attacks. Uses: Scientific research. Group: Natural products. Alternative Names: MK-521. CAS No. 76547-98-3. Pack Sizes: 250 mg; 500 mg. Product ID: HY-18206. | |
| Lisinopril dihydrate | Lisinopri dihydrate (MK-521 dihydrate) is angiotensin-converting enzyme inhibitor, used in treatment of hypertension, congestive heart failure, and heart attacks. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-521 dihydrate. CAS No. 83915-83-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-18206A. | |
| (±)-Lisofylline | (±)-Lisofylline ((±)-Lisophylline) is the racemate of Lisofylline. Lisofylline inhibits the generation of phosphatidic acid and free fatty acids. Lisofylline also blocks the release of pro-inflammatory cytokines in oxidative tissue injury, in response to cancer chemotherapy and in experimental sepsis. Lisofylline can be used for Type 1 diabetes research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (±)-Lisophylline. CAS No. 6493-6-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-126042. | |
| L-Isoleucine | L-Isoleucine is an orally active branched chain amino acid, which is the L-enantiomer of isoleucine. L-Isoleucine has a role as a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite, a plant metabolite, a human metabolite, an algal metabolite and a mouse metabolite. L-Isoleucine regulates the inflammatory response to protect against pathogens in vivo and in vitro [1]. Uses: Scientific research. Group: Natural products. CAS No. 73-32-5. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-N0771. | |
| L-Isoleucine-1-13C | L-Isoleucine-1- 13 C is the 13 C-labeled L-Isoleucine. L-isoleucine is a nonpolar hydrophobic amino acid[1]. L-Isoleucine is an essential amino acid. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 81202-01-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-N0771S4. | |
| L-Isoleucine-13C6 | L-Isoleucine- 13 C 6 is the 13 C-labeled L-Isoleucine. L-isoleucine is a nonpolar hydrophobic amino acid[1]. L-Isoleucine is an essential amino acid. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 201740-82-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N0771S. | |
| L-Isoleucine-d10 | L-Isoleucine-d 10 is the deuterium labeled L-Isoleucine. L-isoleucine is a nonpolar hydrophobic amino acid[1]. L-Isoleucine is an essential amino acid. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 35045-71-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N0771S3. | |
| Lissamine rhodamine B | Lissamine rhodamine B is a red-fluorescent dye, it is a derivative of rhodamine. Lissamine rhodamine B can be used as a fluorescent probe to develop competitive aptamer fluorescence anisotropy/polarization (FA/FP) assays [1] [2]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 2609-88-3. Pack Sizes: 100 mg. Product ID: HY-117468. | |
| Lisuride | Lisuride is an orally active dopamine D2 receptors agonist. Lisuride, as an ergot derivative, can be used for the research of Parkinson's disease, migraine, and high prolactin levels [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 18016-80-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-12713. | |
| Lisuride maleate | Lisuride (maleate) is a potent agonist of dopamine with a probably direct action on dopaminergic receptors. Lisuride (maleate) is an ergot derivative. Lisuride (maleate) releases the premenstrual mastalgia without significant side effects [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 19875-60-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-110080. | |
| Lithium carbonate | Lithium carbonate (Carbolithium) is a biochemical reagent that can be used as a biological material or organic compound for life science related research [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Carbolithium; Lithium carbonate. CAS No. 554-13-2. Pack Sizes: 25 g. Product ID: HY-Y0292. | |
| Lithium chloride hydrate | Lithium chloride hydrate, an orally active mood stabilizer, is a potent virus inhibitor and effective immunomodulatory agent. Lithium chloride hydrate has antidepressant activity by inhibiting GSK3β and promoting neurogenesis. Lithium chloride hydrate alleviates cognition dysfunction and the symptoms of acute mania and depression. Lithium chloride hydrate can also be used for research of virus infection and Alzheimer's disease [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: hydrate/monohydrateortrihydrate. CAS No. 85144-11-2. Pack Sizes: 100 mg. Product ID: HY-W094474. | |
| Lithium citrate tetrahydrate | Lithium citrate (Litarex) tetrahydrate is the major active ingredient of Garcinia cambogia. Lithium citrate tetrahydrate competitively inhibits ATP citrate lyase with weight loss benefits. Lithium citrate tetrahydrate effective inhibits stones formation and also inhibits HIF , and has antioxidation, anti-inflammation and anti-tumor effects [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Litarex tetrahydrate. CAS No. 6080-58-6. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-B1295. | |
| Lithium dodecyl sulfate | Lithium dodecyl sulfate is an anionic detergent and surfactant that can be used in place of SDS for electrophoresis under low temperatures. Lithium dodecyl sulfate can be used for synthesis of nanomaterials and chromatography [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 2044-56-6. Pack Sizes: 5 g; 10 g. Product ID: HY-W099535. | |
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