MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| H-8 dihydrochloride | H-8 (dihydrochloride) is a cell-permeable, reversible and ATP-competitive PKA inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 113276-94-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-112465. |  |
| H-9 Dihydrochloride | H-9 Dihydrochloride is a PKA (protein kinase) inhibitor. H-9 Dihydrochloride (10 μM) significantly reduces the excitatory response to 5-HT. H-9 Dihydrochloride also has a direct effect on pharyngeal activity. H-9 Dihydrochloride inhibits signal-transduction and cell growth in EGF (epidermal growth factor)-dependent epithelial cell lines [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 116700-36-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-100923. | |
| HA-100 | HA-100 is a potent protein kinase inhibitor, with IC 50 s of 4 μM, 8 μM, 12 μM and 240 μM for cGMP-dependent protein kinase (PKG) , cAMP-dependent protein kinase (PKA) , protein kinase C (PKC) and MLC-kinase , respectively. HA-100 also used as a ROCK inhibitor [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 84468-24-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100984. | |
| HA-1004 | HA-1004 is a selective inhibitor of PKA, which can inhibit lipolysis and induce vascular relaxation. HA-1004 is also a dual inhibitor of cyclic GMP-dependent protein kinase and cyclic AMP-dependent protein, and is involved in smooth muscle, second messenger, cyclic AMP and cyclic GMP regulation mechanisms. HA-1004 is an antagonist for calcium , that can be used as a vasodilator to inhibit the contraction of rabbit aortic strips, or to antagonize ERK and tyrosine hydroxylase (TH) phosphorylation in morphine abstinence rat models [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 91742-10-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-123468. | |
| HA130 | HA130 is a selective autotaxin (ATX) inhibitor with an IC 50 of 28 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1229652-21-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-19329. | |
| HA15 | HA15 is a potent and specific inhibitor of ER chaperone BiP/GRP78/HSPA5, inhibits the ATPase activity of BiP, with anti-cancerous activity[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1609402-14-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100437. | |
| HA155 | HA-155 is a potent and selective autotaxin (ATX) inhibitor with an IC 50 of 5.7 nM [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1312201-00-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-116100A. | |
| HA-9104 | HA-9104 is a potent and selective inhibitor of cullin-5 neddylation via virtually targeting the V30 pocket of UBE2F. HA-9104 binds to UBE2F, reduces its protein levels, and consequently inhibits cullin-5 neddylation. HA-9104 has potent growth suppression and radiosensitizing activities via targeting the UBE2F-CRL5 axis and causing DNA damage, leading to induction of apoptosis and G2/M arrest in lung and pancreatic cancer cells[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2412367-83-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-160799. | |
| HA-CD44 interaction inhibitor 1 | HA-CD44 interaction inhibitor 1 (compound 6) is an inhibitor of hyaluronic acid (HY-B0633A) targeting to CD44, as well as an anti-tumor agent. Hyaluronic acid interacts with differentiation cluster 44 (CD44) and is involved in tumor growth and invasion. HA-CD44 interaction inhibitor 1 inhibits MDA-MB-231 cells with EC50 value of 1.77 ?M[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3052354-70-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-149898. | |
| HA-CD44 interaction inhibitor 2 | HA-CD44 interaction inhibitor 2 (compound 5) is an Hyaluronic acid (HA)-CD44 interaction inhibitor that effectively disrupts the integrity of cancer spheroids. HA-CD44 interaction inhibitor 2 also exhibits antiproliferative activity against cancer cells. Antitumor agent-109 inhibits MDA-MB-231 cells with EC50 value of 0.59 ?M[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3009761-01-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-149897. | |
| HADA hydrochloride | HADA hydrochloride (HCC-Amino-D-alanine hydrochloride) is a blue (λ em ~450 nm) fluorescent D-amino acid (FDAA). FDAAs are efficiently incorporated into the peptidoglycans (PGs) of diverse bacterial species at the sites of PG biosynthesis, allowing specific and covalent probing of bacterial growth with minimal perturbation [1]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: HCC-Amino-D-alanine hydrochloride. CAS No. 2253733-10-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-131045. | |
| HAE | HAE is a 3-amino acid peptide which consists of histidine, alanine and glutamate. Uses: Scientific research. Group: Peptides. CAS No. 64111-99-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1232. | |
| HAEGTFT | HAEGTFT is the first N-terminal 1-7 residues of GLP-1 peptide. Uses: Scientific research. Group: Peptides. CAS No. 926018-95-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1228. | |
| HAEGTFTSDVSSYLE | HAEGTFTSDVSSYLE is a polypeptide from patent CN 102920658 B. GLP-I analog contains the sequence. Uses: Scientific research. Group: Peptides. CAS No. 926018-57-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1445. | |
| Halazone | Halazone is an atypical antimicrobial sulfonamide derivative and a carbonic anhydrase II inhibitor with a K d value of 1.45 μM. Halazone protects sodium channels from inactivation. Halazone is widely used for disinfection of drinking water [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 80-13-7. Pack Sizes: 50 mg; 100 mg; 250 mg. Product ID: HY-B1386. | |
| Halcinonide | Halcinonide (SQ-18566) is a high potency corticosteroid used topically in the treatment of certain skin conditions. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SQ-18566. CAS No. 3093-35-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-B0877. | |
| Halicin | Halicin (SU3327) is a potent, selective and substrate-competitive JNK inhibitor with an IC 50 of 0.7 μM. Halicin also inhibits protein-protein interactions between JNK and JNK Interacting Protein (JIP) with an IC 50 of 239 nM. Halicin shows less active against p38α and Akt kinase [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SU3327. CAS No. 40045-50-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-107597. | |
| HaloAUTAC tt15 | HaloAUTAC tt15 is an autophagy-targeting chimera (AUTAC), that targets the Halo Tag carrying proteins, and degrades via the autophagy mechanism[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2241668-45-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-129652. | |
| Halobetasol | Halobetasol (Ulobetasol) is a corticosteroid. Halobetasol can be used for research of severe localized psoriasis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ulobetasol. CAS No. 98651-66-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-113783. | |
| Halobetasol (propionate) | Halobetasol propionate is a synthetic corticosteroid for topical dermatological use; exhibits anti-inflammatory, antipruritic, and vasoconstrictive properties. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMY-30056; CGP-14458; Ulobetasol propionate. CAS No. 66852-54-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0878. | |
| Halobetasol (propionate) (Standard) | Halobetasol (propionate) (Standard) is the analytical standard of Halobetasol (propionate). This product is intended for research and analytical applications. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMY-30056(Standard); CGP-14458(Standard); Ulobetasol propionate (Standard). CAS No. 66852-54-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0878R. | |
| Halocarban | Halocarban is a chemical with antibacterial properties sometimes used in deodorant and soap [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Cloflucarban. CAS No. 369-77-7. Pack Sizes: 25 mg; 50 mg. Product ID: HY-116587. | |
| Halo-DBCO | Halo-DBCO is a click chemistry reagent containing dibenzocyclooctyne (DBCO). Halo-DBCO can be used as a ligand to react with HaloTag to form covalent HaloTag ligand couples[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1808119-16-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-151716. | |
| Halofantrine hydrochloride | Halofantrine hydrochloride (SKF-102886) is a blocker of delayed rectifier potassium current via the inhibition of human-ether-a-go-go-related gene (HERG) channel and a potent antimalarial compound [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SKF-102886; WR-171669 hydrochloride. CAS No. 36167-63-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-A0148A. | |
| Halofuginone | Halofuginone (RU-19110), a Febrifugine derivative, is a competitive prolyl-tRNA synthetase inhibitor with a K i of 18.3 nM [1] [2]. Halofuginone is a specific inhibitor of type-I collagen synthesis and attenuates osteoarthritis (OA) by inhibition of TGF-β activity [3] [4]. Halofuginone is also a potent pulmonary vasodilator by activating Kv channels and blocking voltage-gated, receptor-operated and store-operated Ca 2+ channels. Halofuginone has anti-malaria, anti-inflammatory, anti-cancer, anti-fibrosis effects [5]. Uses: Scientific research. Group: Natural products. Alternative Names: RU-19110. CAS No. 55837-20-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N1584. | |
| Halofuginone hydrobromide | Halofuginone (RU-19110) hydrobromid, a Febrifugine derivative, is a competitive prolyl-tRNA synthetase inhibitor with a K i of 18.3 nM [1] [2]. Halofuginone hydrobromid is a specific inhibitor of type-I collagen synthesis and attenuates osteoarthritis (OA) by inhibition of TGF-β activity [3] [4]. Halofuginone hydrobromid is also a potent pulmonary vasodilator by activating Kv channels and blocking voltage-gated, receptor-operated and store-operated Ca 2+ channels. Halofuginone hydrobromid has anti-malaria, anti-inflammatory, anti-cancer, anti-fibrosis effects [5]. Uses: Scientific research. Group: Natural products. Alternative Names: RU-19110 hydrobromide. CAS No. 64924-67-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-N1584A. | |
| Halofuginone lactate | Halofuginone lactate, a Febrifugine derivative, is a competitive prolyl-tRNA synthetase inhibitor with a K i of 18.3 nM [1] [2]. Halofuginone lactate is a specific inhibitor of type-I collagen synthesis and attenuates osteoarthritis (OA) by inhibition of TGF-β activity [3] [4]. Halofuginone lactate is also a potent pulmonary vasodilator by activating Kv channels and blocking voltage-gated, receptor-operated and store-operated Ca 2+ channels. Halofuginone lactate has anti-malaria, anti-inflammatory, anti-cancer, anti-fibrosis effects [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RU-19110 lactate. CAS No. 82186-71-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N1584C. | |
| Halofuginone (Standard) | Halofuginone (Standard) is the analytical standard of Halofuginone. This product is intended for research and analytical applications. Halofuginone (RU-19110), a Febrifugine derivative, is a competitive prolyl-tRNA synthetase inhibitor with a Ki of 18.3 nM [1] [2]. Halofuginone is a specific inhibitor of type-I collagen synthesis and attenuates osteoarthritis (OA) by inhibition of TGF-β activity [3] [4]. Halofuginone is also a potent pulmonary vasodilator by activating Kv channels and blocking voltage-gated, receptor-operated and store-operated Ca2+ channels. Halofuginone has anti-malaria, anti-inflammatory, anti-cancer, anti-fibrosis effects [5]. Uses: Scientific research. Group: Natural products. CAS No. 55837-20-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N1584R. | |
| Haloperidol | Haloperidol is a potent dopamine D2 receptor antagonist, widely used as an antipsychotic. Uses: Scientific research. Group: Signaling pathways. CAS No. 52-86-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-14538. | |
| Haloperidol decanoate | Haloperidol decanoate shows antipsychotic activity. Haloperidol decanoate can be used in schizophrenia and schizoaffective disorder research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 74050-97-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107969. | |
| Haloperidol (Standard) | Haloperidol (Standard) is the analytical standard of Haloperidol. This product is intended for research and analytical applications. Haloperidol is a potent dopamine D2 receptor antagonist, widely used as an antipsychotic. Uses: Scientific research. Group: Signaling pathways. CAS No. 52-86-8. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14538R. | |
| Haloprogin | Haloprogin is a potent antifungal agent. Haloprogin has activity against dermatophytes, Candida spp and a limited number of Gram-positive bacteria [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 777-11-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16246. | |
| HaloPROTAC-E | HaloPROTAC-E is a potent Halo PROTAC degrader that reversibly induces degradation of two Halo-tagged endoplasmic reticulum-localized proteins, SGK3 and VPS34, with a DC50 of 3-10 nM. HaloPROTAC-E significantly and selectively induces degradation of endogenous VPS34 complexes (VPS34, VPS15, Beclin1, and ATG14) labeled with Halo and inhibits autophagy. Uses: Scientific research. Group: Signaling pathways. CAS No. 2365478-58-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-145752. | |
| Halosulfuron-methyl | Halosulfuron-methyl is a pyrazole sulfonylurea herbicide [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Inpool; MON 12000; Manage. CAS No. 100784-20-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-B1850. | |
| Halo tag TMR | Halo tag TMR is a red fluorescent dye composed of Halo tag ligand molecules and TMR. Halo tag can quickly and stably covalently bind to Halo protein with high specificity and affinity[1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 2764890-88-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D2270. | |
| Haloxon | Haloxon is an anti-parasitic agent. Haloxon can be used for the research of infections of Parascaris equorum, Oxyuris equi and Strongylus vulgaris. Haloxon also can be used in control of ascarids and hookworms in domesticated animals in combination with Bidimazium [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 321-55-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-17532. | |
| Haloxyfop-methyl | Haloxyfop-methyl is a high-efficacy herbicide. Haloxyfop-methyl selectively controls several annual and perennial grasses in soybeans and other dicotyledenous crops [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 69806-40-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W286307. | |
| Hamamelitannin | Hamamelitannin, a polyphenol extracted from the bark of Hamamelis virginiana , is a quorum-sensing (QS) inhibitor. Hamamelitannin increases antibiotic susceptibility of staphylococcus aureus biofilms by affecting peptidoglycan biosynthesis and eDNA release [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 469-32-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N4117. | |
| HAMI 3379 | HAMI 3379 is a potent and selective CysLT2 receptor antagonist. HAMI 3379 has a protective effect on acute and subacute ischemic brain injury, and attenuates microglia-related inflammation[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1245653-57-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112248A. | |
| HAMNO | HAMNO is a novel protein interaction inhibitor of replication protein A (RPA). Uses: Scientific research. Group: Signaling pathways. Alternative Names: NSC111847. CAS No. 138736-73-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111285. | |
| Handelin | Handelin is a guaianolide dimer from Chrysanthemum boreale that has potent anti-inflammatory activity by down-regulating NF-?B signaling and pro-inflammatory cytokine production[1]. Uses: Scientific research. Group: Natural products. CAS No. 62687-22-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N2083. | |
| HAP-1 | HAP-1 is a synovial-targeted transduction peptide. HAP-1 facilitates specific internalization of protein complexes into human and rabbit synovial cells. HAP-1 fused to an antimicrobial peptide, (KLAK) 2 , to generate a proapoptotic peptide DP2 [1]. Uses: Scientific research. Group: Peptides. CAS No. 329004-38-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P4096. | |
| HA Peptide | HA Peptide (HA tag) is a nine amino acids peptide derived from the human influenza hemagglutinin (HA). HA Peptide is extensively used to isolate, purify, detect, and track the protein of interest in cell biology and biochemistry. Uses: Scientific research. Group: Peptides. CAS No. 92000-76-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0239. | |
| HAPSBC | HAPSBC is an S-benzyl iron chelator that mobilizes intracellular 59 Fe distribution [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1376545-81-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156776. | |
| Hapten C | Hapten C is a derivative of histamine. Hapten C is utilized for synthesis of immunogens and coating antigens, that can quantitative determine the histamine via ELISA [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 90579-19-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108026. | |
| H-Arg-NH2 hydrochloride | H-Arg-NH2 (hydrochloride) is a nucleophilic reagent that can be used in experiments related to enzyme activity center detection [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 14975-30-5. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-W011985. | |
| Harmalol hydrochloride | Harmalol hydrochloride, a beta carboline alkaloid, presents in several medicinal plants such as Peganum harmala. Harmalol hydrochloride, main metabolite of Harmaline, significantly inhibits the dioxin-mediated induction of CYP1A1 at the transcriptional and posttranslational levels. Harmalol hydrochloride possesses antioxidant and hydroxyl radical-scavenging properties [1]. Uses: Scientific research. Group: Natural products. CAS No. 6028-7-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N2625A. | |
| Harmane | Harmane is a benzodiazepine receptor inhibitor ( IC 50 =7 μM), with IC 50 values for mACh , Opioid Receptor , MAO-A/B , and α2-adrenergic receptor of 24 μM, 2.8 μM, 0.5 μM, 5 μM, and 18 μM, respectively. Harmane inhibits the I1 imidazoline receptor ( IC 50 = 30 nM) to reduce blood pressure and has antidepressant, anti-anxiety, anticonvulsant, and analgesic effects. Harmane inhibits dopamine biosynthesis by decreasing tyrosine hydroxylase (TH) activity and enhancing L-DOPA-induced cytotoxicity in PC12 cells. Additionally, Harmane can increase the mutagenic effect induced by 2-acetylaminofluorene (AAF) [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Natural products. CAS No. 486-84-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-101392. | |
| Harmine | Harmine is a natural dual-specificity tyrosine phosphorylation-regulated kinase ( DYRK ) inhibitor with anticancer and anti-inflammatory activities. Harmine has a high affinity of 5-HT 2A serotonin receptor , with an K i of 397 nM [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Telepathine. CAS No. 442-51-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-N0737A. | |
| Harmine hydrochloride | Harmine Hydrochloride (Telepathine Hydrochloride) is a natural DYRK inhibitor with anticancer and anti-inflammatory activities. Harmine has a high affinity of 5-HT 2A serotonin receptor , with an K i of 397 nM [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Telepathine hydrochloride. CAS No. 343-27-1. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-N0737. | |
| Harmol | Harmol is a TFEB activator, an orally active monoamine oxidase inhibitor that has anti-tumor, anti-depressant, and anti-aging effects. Harmol can induce cell mitosis, autophagy and apoptosis. Harmol promotes the degradation of α-synuclein through the regulation of the autophagy-lysosomal pathway, improving motor deficits in mouse models of Parkinson's disease [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 487-03-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-107811. | |
| Harpagoside | Harpagoside can be obtained by Harpagophytum procumbens , which has anti-inflammatory, anti-cancer, protective activity, and efficacy. Harpagoside has an inhibitory effect on COX-1 and COX-2 active, and suppresses NO production. Harpagoside inhibits HepG2 cell lipid polysaccharide, which is a protein that is expressed horizontally and selectively, and has anti-inflammatory and latent pain effects. Harpagoside has the ability to protect the body, and has a degenerative effect on the β-oxidation (Aβ) [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 19210-12-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 20 mg. Product ID: HY-N0396. | |
| Harringtonine | Harringtonine is a natural Cephalotaxus alkaloid that inhibits protein synthesis. Harringtonine has anti- chikungunya virus (CHIKV) activities with an EC 50 of 0.24 μM. Uses: Scientific research. Group: Natural products. CAS No. 26833-85-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N0862. | |
| HATU | HATU (1-[Bis(dimethylamino)methylene]-1H-1,2,3-triazolo[4,5-b]pyridinium 3-oxid hexafluorophosphate) is a reagent used in peptide coupling chemistry to generate an active ester from a carboxylic acid. HATU can be used along with Hünig's base (N,N-diisopropylethylamine, DIPEA) to form amide bonds [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 148893-10-1. Pack Sizes: 25 g; 50 g; 100 g. Product ID: HY-Y1703. | |
| HaXS8 | HaXS8 is a dimerizer that can promote a covalent and irreversible intracellular dimerization of HaloTag and SNAP-tagged proteins of interest. HaXS8 does not interfere with PI3K/mTOR signaling[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2080306-25-6. Pack Sizes: 1 mg; 2 mg; 5 mg; 10 mg. Product ID: HY-131015. | |
| HBC | HBC (HBC 530) is a GFP fluorophore-like synthetic dye, with a structurally rigid electron acceptor and a strong electron donor. HBC is nonfluorescent in solution, and when combined with Pepper (RNA aptamer), HBC forms a tight complex and activates and emits bright fluorescence ( K d of ~3.5 nM). HBC emission peaks vary in different complexes and covers the spectrum from cyan to red. HBC can be used in the live cell imaging of RNA [1]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: HBC 530. CAS No. 156840-13-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D1373. | |
| HbF inducer 2 | HbF inducer 3 (Compound dWIZ-2) is an orally active molecular glue, which degrades the WIZ transcription factor (DC50=13 nM in primary human erythroid precursor cell) and induces the expression of fetal hemoglobin (HbF) (EC50=100 nM). HbF inducer 3 exhibits good pharmacokinetic characteristics in cynomolgus monkeys[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2654011-51-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-159099. | |
| HBTU | HBTU is a coupling agent commonly used for the activation of free carboxylic acids during the solution and solid phase peptide synthesis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: N-HBTU. CAS No. 94790-37-1. Pack Sizes: 25 g; 50 g; 100 g. Product ID: HY-Y0912. | |
| HBV-IN-37 | HBV-IN-37 is an inhibitor of HBV with an EC 50 value of 10 μM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 380483-01-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-156665. | |
| HC-030031 | HC-030031 is a potent and selective TRPA1 inhibitor, which antagonizes AITC- and formalin-evoked calcium influx with IC 50 s of 6.2±0.2 and 5.3±0.2 μM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 349085-38-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15064. | |
| HC-056456 | HC-056456 is an effective but not perfectly-selective blocker of CatSper channels. The [Na+]i rise is slowed by HC-056456 (IC50~3 μM). Uses: Scientific research. Group: Signaling pathways. Alternative Names: 3,4-Bis(2-thienoyl)-1,2,5-oxadiazole-N-oxide. CAS No. 7733-96-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112729. | |
| HC-067047 | HC-067047 is a potent and selective TRPV4 antagonist and reversibly inhibits currents through the human, rat, and mouse TRPV4 orthologs with IC 50 values of 48 nM, 133 nM, and 17 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 883031-03-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100208. | |
| HC-5404-Fu | HC-5404-Fu is a PERK inhibitor with an antitumor activity. HC-5404-Fu inhibits endoplasmic reticulum stress response signalling. HC-5404-Fu sensitizes renal cell carcinoma cells to vascular endothelial growth factor (VEGF) receptor tyrosine kinase inhibitors ( TKIs ). HC-5404-Fu is promising for research of renal cell carcinoma, gastric cancer, metastatic breast cancer, small cell lung cancer, and other solid tumors [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3034479-99-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-157231A. | |
| HC-7366 | HC-7366 (compound 3) has GCN2 inhibitory activity, with the IC 50 value less than 0.05 μM. HC-7366 plays an important role in anti-tumor research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GCN2 modulator-1. CAS No. 2803470-63-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-160196. | |
| HCGRP-(8-37) | HCGRP-(8-37) is a human calcitonin gene-related peptide (hCGRP) fragment and also an antagonist of CGRP receptor. Uses: Scientific research. Group: Peptides. Alternative Names: Human ?-CGRP (8-37). CAS No. 119911-68-1. Pack Sizes: 500 ?g; 1 mg; 5 mg; 10 mg. Product ID: HY-P1014. | |
| HCH6-1 | HCH6-1 is a potent and competitive dipeptide antagonist of Formyl peptide receptor 1 (FPR1). HCH6-1 inhibits chemotaxis, superoxide anion generation, and elastase release in human neutrophils specifically activated by fMLF (an FPR1 agonist). HCH6-1 has protective effects against acute lung injury (ALI) in vivo and can be used for the research of FPR1-involved inflammatory lung diseases[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1435265-06-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101283. | |
| HCoV-229E-IN-1 | HCoV-229E-IN-1 is a potent inhibitor of HCoV-229E replication, with an EC 50 of 0.65 μM and 0.6 μM in MTS and CPE cells, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2639757-13-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132169. | |
| HCoV-OC43-IN-1 | HCoV-OC43-IN-1 (Compound IV-16) is a coronavirus HCoV-OC43 inhibitor. HCoV-OC43-IN-1 has antiviral efficacy (EC 50 : 90 nM). HCoV-OC43-IN-1 inhibits the mRNA level and expression of viral nucleocapsid protein (NP) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2809363-81-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-156346. | |
| HC-Toxin | HC-Toxin, a cyclic tetrapeptide, is a potent HDAC inhibitor with an IC 50 of 30 nM [1]. HC-Toxin induces tumor cell apoptosis and has anticancer effects [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 83209-65-8. Pack Sizes: 500 μg; 1 mg. Product ID: HY-126856. | |
| HCTU | HCTU is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: O-(6-Chlorobenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate. CAS No. 330645-87-9. Pack Sizes: 10 mM * 1 mL; 5 g; 10 g. Product ID: HY-W010951. | |
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