MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| LY 303511 hydrochloride | LY 303511 hydrochloride is a structural analogue of LY294002. LY303511 does not inhibit PI3K. LY303511 enhances TRAIL sensitivity of SHEP-1 neuroblastoma cells. LY303511 reversibly blocks K + currents (IC 50 =64.6±9.1 μM) in MIN6 insulinoma cells. Uses: Scientific research. Group: Signaling pathways. CAS No. 2070014-90-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15643A. |  |
| LY3154207 | LY3154207 is a potent, subtype selective, and orally available human dopamine D1 receptor positive allosteric modulator (PAM) with minimal allosteric agonist activity ( EC 50 =3 nM) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1638667-79-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-128770. | |
| LY3200882 | LY3200882 is a potent, highly selective, ATP-competitive and orally active TGF-β receptor type 1 (ALK5) inhibitor with an IC 50 of 38.2 nM. LY3200882 inhibits various pro-tumorigenic activities and is also used as an immune modulatory agent [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1898283-02-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103021. | |
| LY3295668 | LY3295668 (AK-01) is a potent, orally active and highly specific Aurora-A kinase inhibitor, with K i values of 0.8 nM and 1038 nM for AurA and AurB, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AK-01. CAS No. 1919888-06-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114258. | |
| LY 344864 | LY 344864 is a selective, orally active 5-HT 1F receptor agonist with a K i of 6 nM. LY 344864 is a full agonist producing an effect similar in magnitude to serotonin itself. LY 344864 can cross the blood brain barrier to some extent [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 186544-26-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13788. | |
| LY 344864 racemate | LY 344864 racemate is a 5-HT 1F receptor agonist extracted from patent US 5708187 A. Uses: Scientific research. Group: Signaling pathways. CAS No. 186543-64-6. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13788C. | |
| LY3522348 | KHK-IN-3 (Example 1) is a ketohexokinase ( KHK ) inhibitor. KHK-IN-3 can be used in the study of kidney disease, nonalcoholic steatohepatitis (NASH), diabetes and heart failure. KHK is a rate-limiting enzyme and fructokinase involved in fructose metabolism. KHK catalyzes the phosphorylation of fructose to fructose-1-phosphate (FIP) at the expense of ATP. The lack of feedback inhibition of fructose metabolism triggers the accumulation of downstream intermediates such as lipogenesis, gluconeogenesis, and oxidative phosphorylation [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KHK-IN-3. CAS No. 2568608-48-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-149987. | |
| LY367385 | LY367385 is a highly selective and potent mGluR1a antagonist. LY367385 has an IC 50 of 8.8 μM for inhibiting of quisqualate-induced phosphoinositide (PI) hydrolysis, compared with >100 μM for mGlu5a. LY367385 has neuroprotective, anticonvulsant and antiepileptic effects [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 198419-91-9. Pack Sizes: 1 mg. Product ID: HY-107515. | |
| (±)-LY367385 | (±)-LY367385 is the racemate of LY367385. LY367385 is a highly potent and selective mGluR1a antagonist. LY367385 has an IC 50 of 8.8 μM for inhibits of quisqualate-induced phosphoinositide (PI) hydrolysis, compared with > 100 μM for mGlu5a [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 198419-90-8. Pack Sizes: 1 mg. Product ID: HY-135464. | |
| LY367385 hydrochloride | LY367385 hydrochloride is a highly selective and potent mGluR1a antagonist. LY367385 hydrochloride has an IC 50 of 8.8 μM for inhibiting of quisqualate-induced phosphoinositide (PI) hydrolysis, compared with >100 μM for mGlu5a. LY367385 hydrochloride has neuroprotective, anticonvulsant and antiepileptic effects [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2829282-00-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107515A. | |
| LY393558 | LY393558 is a potent and orally active inhibitor of the 5-HT transporter and an antagonist of 5-HT1B and 5-HT1D receptors. LY393558 increase the extracellular levels of 5-HT in mice model frontal cortex. LY393558 can be used for researching depression [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 271780-64-4. Pack Sizes: 1 mg. Product ID: HY-103089. | |
| LY-404187 | LY-404187 is a potent, selective and centrally active positive allosteric modulator of AMPA receptors , with the EC 50 s of 5.65, 0.15, 1.44, 1.66 and 0.21 μM for GluR1i , GluR2i , GluR2o , GluR3i and GluR4i , respectively. LY-404187 has therapeutic potential in a number of psychiatric disorders and neurodegenerative diseases [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 211311-95-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-13456. | |
| LY456236 | LY456236 is a selective, non-competitive and orally active mGlu1 receptor antagonist that inhibits phosphoinositide hydrolysis with an IC 50 of 0.145 μM. LY456236 also inhibits EGFR with an IC 50 of 0.91 μM [1] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 338736-46-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-103566. | |
| LY487379 | LY487379 is a selective human mGluR2 positive allosteric modulator (PAM). LY487379 potentiates glutamate-stimulated [ 35 S]GTPγS binding with EC 50 values of 1.7 μM and >10 μM for mGlu2 and mGlu3 receptors respectively. LY487379 promotes cognitive flexibility and facilitates behavioral inhibition in a rat model. LY487379 can be used for schizophrenia research [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 353231-17-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122255. | |
| Lycopene | Lycopene is naturally occurring carotenoids found in tomato, tomato products, and in other red fruits and vegetables; exhibits antioxidant effects. Uses: Scientific research. Group: Natural products. CAS No. 502-65-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N0287. | |
| Lycorine | Lycorine is a natural alkaloid extracted from the Amaryllidaceae plant. Lycorine is a potent and orally active SCAP inhibitor with a K d value 15.24 nM. Lycorine downregulates the SCAP protein level without changing its transcription [2]. Lycorine is also a melanoma vasculogenic inhibitor [3]. Lycorine can be used for the study of prostate cancer and metabolic diseases [2]. Uses: Scientific research. Group: Natural products. CAS No. 476-28-8. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-N0288. | |
| Lycorine hydrochloride | Lycorine hydrochloride is the main active ingredient of the herbal medicine derived from Lycoris radiata (LHer.) Herb. and is also a melanoma vasculogenic inhibitor and has anti-tumor activity [1]. Lycorine hydrochloride effectively inhibits mitotic proliferation of Hey1B cells ( IC 50 of 1.2 μM) [2]. Uses: Scientific research. Group: Natural products. CAS No. 2188-68-3. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-N0289. | |
| Lycorine Hydrochloride Monohydrate | Lycorine Hydrochloride Monohydrate is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 6150-58-9. Pack Sizes: 100 mg; 250 mg. Product ID: HY-N0288A. | |
| Lymecycline | Lymecycline is a tetracycline derivative, with broad-spectrum antibacterial activity and also has anti-inflammatory property. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Mucomycin. CAS No. 992-21-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106339. | |
| Lynestrenol | Lynestrenol is a pregnane X receptor ( PXR ) agonist with the EC 50 s of 41 and 0.23 μM for hPXR and zfPXR, respectively [1]. Lynestrenol, a synthetic progesteronelike agent possess immunostimulatory properties [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 52-76-6. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-109568. | |
| Lys05 | Lys05 (Lys01 trihydrochloride) is a novel lysosomal autophagy inhibitor with IC 50 values of 3.6, 3.8, 6 and 7.9 μM for 1205Lu, c8161, LN229 and HT-29 cell line in the MTT assay. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Lys01 trihydrochloride. CAS No. 1391426-24-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12855A. | |
| Lys-[Des-Arg9]Bradykinin TFA | Lys-[Des-Arg9]Bradykinin TFA, a naturally occurring kinin, is a potent and highly selective bradykinin B1 receptor agonist with a K i of 0.12 nM, 1.7 nM and 0.23 nM for human , mouse and rabbit B1 receptors , respectively. Lys-[Des-Arg9]Bradykinin TFA has low inhibitory activity on B2 receptors [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 2763588-90-3. Pack Sizes: 5 mg; 10 mg; 50 mg. Product ID: HY-103295A. | |
| Lysipressin | Lysipressin (Lysine vasopressin) is antidiuretic hormone that have been found in pigs. Lysipressin activates Oxytocin receptors and adenylate-cyclase. Lysipressin adjusts blood pressure and heart rate. Lysipressin shows antinociceptive activity [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Peptides. Alternative Names: Lysine vasopressin; [Lys8]-Vasopressin. CAS No. 50-57-7. Pack Sizes: 2 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-P0004. | |
| Lysipressin acetate | Lysipressin (Lysine vasopressin) acetate is antidiuretic hormone that have been found in pigs and some marsupial families. Lysipressin acetate induces contraction of the rabbit urinary bladder smooth muscle, activate adenylate-cyclase [1] [2]. Uses: Scientific research. Group: Peptides. Alternative Names: Lysine vasopressin acetate; [Lys8]-Vasopressin acetate. CAS No. 83968-49-4. Pack Sizes: 2 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-P0004A. | |
| Lyso-PAF C-16 | Lyso-PAF C-16 is a substrate of lysoplasmalogen (LysoPls)-specific phospholipase D (LysoPLD). Lyso-PAF C-16 selective acetylates with arachidonic acid [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 52691-62-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-141570. | |
| Lyso-PAF C-18 | Lyso-PAF C-18 is an intermediate for the synthesis of C18-PAF (HY-130345). It has an easily substituted "Lyso-PAF" structure and is easy to purify and has high yield. C18-PAF is a ligand for platelet-activating factor and PAF G protein-coupled receptor (PAFR) and has renovasodilator properties and antihypertensive lipid properties [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 74430-89-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-141581. | |
| LysoPC(16:1(9Z)) | LysoPC(16:1(9Z)) is a type of lysophosphatidylcholine that can be used to study spleen deficiency syndrome [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 76790-27-7. Pack Sizes: 1 mg (20.26 mM * 100 μL in Ethanol); 5 mg (20.26 mM * 500 μL in Ethanol). Product ID: HY-113470. | |
| Lysophosphatidylcholines | Lysophosphatidylcholines is an orally active lysolipid and a component of oxidized low density lipoprotein (LDL). Lysophosphatidylcholines induces cell injury, the production of IL-1β and apoptosis. Lysophosphatidylcholines has a proactive effect on sepsis [1] [2] [3] [4]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 9008-30-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139414. | |
| Lysophosphatidylethanolamines, egg | Lysophosphatidylethanolamine (LPE) is a naturally-occurring lysophospholipid that can be generated via deacylation of phosphatidylethanolamine by phospholipase A2 (PLA2). It increases the phosphorylation of ERK1/2 in PC12 cells, an effect that can be blocked by the MEK inhibitors U-0126 (HY-12031A) and PD 98059 (HY-12028) and the EGFR inhibitor AG-1478 (HY-13524).1 LPE also increases neurite outgrowth and expression of neurofilament M in PC12 cells. LPE inhibits the activity of phospholipase D (PLD) partially purified from cabbage.3 This product contains lysophosphatidylethanolamine molecular species with variable fatty acyl chain lengths at the sn-1 position and a hydroxy group at the sn-2 position. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Lyso-PE (egg); LPE (egg); L-α-lysophosphatidylethanolamine. CAS No. 97281-40-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-156041. | |
| Lysostaphin | Lysostaphin is an antistaphylococcal agent. Lysostaphin has activities of three enzymes namely, glycylglycine endopeptidase, endo-β-N-acetyl glucosamidase and N-acteyl muramyl-L-alanine amidase [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 9011-93-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P2329. | |
| Lysozyme | Lysozyme (Muramidase) is a conserved antimicrobial protein. Lysozyme exerts its bactericidal effect by hydrolyzing bacterial cell wall peptidoglycan (PG). Lysozyme plays an important role in limiting bacterial growth on mucosal surfaces and other sites, not only controlling potential pathogens but also limiting overgrowth of microbiota to prevent dysbiosis. Extracellular lysozyme can also degrade polymeric PG into soluble fragments, activate NOD receptors in mucosal epithelial cells, and lead to the secretion of chemokines and activating factors by neutrophils and macrophages [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Muramidase. CAS No. 9001-63-2. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-P1068. | |
| Lysozyme from chicken egg white | Lysozyme from chicken egg white is a bactericidal enzyme, and it lyses gram-positive bacteria. Lysozyme from chicken egg white can also be used for the research of HIV infection and pulmonary emphysema [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 12650-88-3. Pack Sizes: 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B2237. | |
| M-110 | M-110 is a highly selective, ATP-competitive inhibitor of PIM kinases with a preference for PIM-3 (IC 50 =47 nM). M-110 inhibits PIM-1 and PIM-2 with similar IC 50 s of 2.5 μM. M-110 inhibits the proliferation of prostate cancer cell lines with IC 50 s of 0.6 to 0.9 μM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1395048-49-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12830. | |
| M1145 | M1145, a chimeric peptide, is a selective galanin receptor type 2 (GAL2) agonist, with a K i of 6.55 nM. M1145 shows more than 90-fold higher affinity for GAL2 over GAL1 (K i =587 nM) and a 76-fold higher affinity over GalR3 (K i =497 nM). M1145 has an additive effect on the signal transduction of galanin [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1172089-00-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1135. | |
| M344 | M344 (D 237) is an inhibitor of histone deacetylase ( IC 50 =100 nM) and an inducer of terminal cell fifferentiation. Uses: Scientific research. Group: Signaling pathways. Alternative Names: D 237; MS 344. CAS No. 251456-60-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-13506. | |
| M47 | M47 is a small molecule that selectively destabilizes Cryptochrome 1 (CRY1) and increases degradation of the CRY1 in the nucleus. M47 enhances apoptosis in Ras-transformed P53-deficient mouse skin fibroblast lines and enhances life span in p53 knockout mice. M47 can be used in research of cancer [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 890808-56-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148764. | |
| M617 | M617 is a selective galanin receptor 1 (GAL1) agonist, with K i s of 0.23 and 5.71 nM for GAL1 and GAL2, respectively. M617, acting through its central GAL1, can promote GLUT4 expression and enhance GLUT4 content in the cardiac muscle of type 2 diabetic rats [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 860790-38-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1131. | |
| M871 | M871 (Galanin-(2-13)-Glu-His-(Pro)3-(Ala-Leu)2-Ala-amide) is a selective galanin receptor type 2 ( GalR2 ) antagonist. M871 exhibits K i values of 13.1 nM and 420 nM for GalR2 and GalR1 , respectively. M871 can be used for research on GalR2 -related diseases (such as epilepsy, pain) [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Galanin-(2-13)-Glu-His-(Pro)3-(Ala-Leu)2-Ala-amide. CAS No. 908844-75-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1130. | |
| M-89 | M-89 is a highly potent and specific menin inhibitor, with a K d of 1.4 nM for binding to menin. M-89 inhibits the menin-mixed lineage leukemia (Menin-MLL) protein-protein interaction and has potential to treat MLL leukemia [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2363165-42-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128347. | |
| Maackiain | Maackiain (DL-Maackiain) is isolated from Maackia amurensis Rupr.et Maxim. Maackiain (DL-Maackiain) is a larvicidal agent against Aedes aegypti mosquito.xp Parasitol with a LD 50 of ?21.95 μg/mL [1]. Maackiain (DL-Maackiain) induces fragmentations of DNA to oligonucleosomal-sized fragments that like a characteristic of apoptosis in the HL-60 cells [2]. Uses: Scientific research. Group: Natural products. Alternative Names: DL-Maackiain. CAS No. 19908-48-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N0381. | |
| Mabuterol | Mabuterol is a selective and orally active beta-2 adrenergic receptor (ADRB2) agonist. Mabuterol inhibits the proliferation and suppresses the increase of intracellular Ca2+ induced by PDGF-BB. Mabuterol suppresses the protein expressions of Drp-1, cyclinD1 and PCNA and enhanced the expression of Mfn-2 induced by PDGF-BB [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 56341-08-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13338. | |
| Macamide B | Macamide B (N-Benzylhexadecanamide; Macamide 1) is a macamide isolated from Lepidium meyenii , acts as an inhibitor of fatty acid amide hydrolase (FAAH). Uses: Scientific research. Group: Natural products. Alternative Names: N-Benzylpalmitamide; N-Benzylhexadecanamide; Macamide 1. CAS No. 74058-71-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N2365. | |
| Macelignan | Macelignan ((+)-Anwulignan; Anwuligan) is an orally active lignan isolated from Myristica fragrans. Macelignan possesses many pharmacological activities, including anti-inflammatory, anti-cancer, anti-diabetes, and neuroprotective activities [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: (+)-Anwulignan; Anwuligan. CAS No. 107534-93-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0064. | |
| Macimorelin acetate | Macimorelin (EP-1572) acetate, a GH secretagogue, is an orally active GHSR agonist. Macimorelin acetate stimulates GH release. Macimorelin acetate can be used in the research of adult growth hormone deficiency (AGHD), and Cancer anorexia-cachexia syndrome (CACS) [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EP-1572 acetate; AEZS-130 acetate. CAS No. 945212-59-9. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-14820A. | |
| Macitentan | Macitentan (ACT-064992) is an orally active, non-peptide dual ETA and ETB (endothelin receptor) antagonist. Macitentan has the potential for idiopathic pulmonary fibrosis (IPF) and pulmonary arterial hypertension (PAH) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ACT-064992. CAS No. 441798-33-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14184. | |
| Macropa | Macropa is a macrocyclic chelator that can be used as radionuclides to study soft tissue metastases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1128304-86-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-160131. | |
| Madecassic acid | Madecassic acid is isolated from Centella asiatica (Umbelliferae). Madecassic acid has anti-inflammatory properties caused by iNOS , COX-2 , TNF-alpha , IL-1beta , and IL-6 inhibition via the downregulation of NF-κB activation in RAW 264.7 macrophage cells [1]. Uses: Scientific research. Group: Natural products. CAS No. 18449-41-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 20 mg. Product ID: HY-N0569. | |
| Madecassoside | Madecassoside is a pentacyclic triterpene isolated from Centella asiatica and has anti-inflammatory properties. Antioxidant and anti-aging effects. Madecassoside is a pentacyclic triterpene isolated from Centella asiatica. Madecassoside is orally active and has inhibitory properties against inflammation, oxidation, apoptosis and autophagy. Madecassosid inhibits activities of p38 MAPK and NF-kB [5][6] , exhibits an anti-apopototic property, activates Nrf2 expression to reduce the neurotoxicity [10]. Madecassoside can be used in endocrine diseases, cardiovascular diseases, skin diseases and other diseases. Uses: Scientific research. Group: Natural products. Alternative Names: Asiaticoside A. CAS No. 34540-22-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-N0568. | |
| Maduramicin ammonium | Maduramicin (Maduramycin) ammonium is isolated from the actinomycete Actinomadura rubra. Maduramicin ammonium is an oral active anticoccidial agent used in research related to Eimeria, Adenosarcina, Enterococcus faecalis, and Enterococcus disperitus infections. Maduramicin ammonium induces apoptosis ( apoptosis ) in chicken cardiomyocytes through both intrinsic and extrinsic pathways and also impairs autophagic flux and induces rhabdomyolysis by activating the AMPK -mediated eIF2α-ATF4 endoplasmic reticulum stress pathway [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Maduramycin ammonium. CAS No. 84878-61-5. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N7071A. | |
| Mafenide Acetate | Mafenide Acetate is an effective sulfonamide-type antimicrobial agent used for burn wounds. Mafenide Acetate shows activity against both Gram-positive and Gram-negative organisms , including Pseudomonas aeruginosa , via inhibition of nucleotide synthesis [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 13009-99-9. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-B0614A. | |
| Mafenide hydrochloride | Mafenide hydrochloride is an effective sulfonamide-type antimicrobial agent used for burn wounds. Mafenide hydrochloride shows activity against both Gram-positive and Gram-negative organisms , including Pseudomonas aeruginosa , via inhibition of nucleotide synthesis [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 138-37-4. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B0614B. | |
| MAFP | MAFP (Methyl Arachidonyl Fluorophosphonate) is an selective, active-site directed and irreversible inhibitor of cPLA2 and iPLA2. MAFP is also a potent irreversible inhibitor of anandamide amidase. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Methyl Arachidonyl Fluorophosphonate. CAS No. 188404-10-6. Pack Sizes: 1 mg (26.99 mM * 100 μL in Methyl acetate). Product ID: HY-103334. | |
| Maftivimab | Maftivimab (REGN3470-3471-3479), the inhibitor of Filovirus , is an Food and agent Administration (FDA)-approved agent. Maftivimab, also named as Atoltivimab, Odesivimab (Inmazeb), can be used for research of Zaire ebolavirus infection [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: REGN3470-3471-3479. CAS No. 2135632-36-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99722. | |
| Magnesium acetate tetrahydrate | Magnesium acetate tetrahydrate is a hydrated form of anhydrous magnesium acetate salt. As a salt form of Magnesium, Magnesium acetate tetrahydrate is one of the bioavailable forms of magnesium and forms a very water soluble compound. Magnesium acetate tetrahydrate can be used as an electrolyte supplementation or a reagent in molecular biology experiments [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 16674-78-5. Pack Sizes: 50 g; 100 g. Product ID: HY-Y0319G. | |
| Magnesium chloride hexahydrate, for molecular biology | Magnesium chloride hexahydrate (MgCl2 hexahydrate), for molecular biology is the hexahydrate form of magnesium dichloride. Magnesium chloride hexahydrate can be used as a source of magnesium ion and a co-foactor for many enzymes. Magnesium chloride hexahydrate increases the activity of Ca 2+ ATPase [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: MgCl2 hexahydrate, for molecular biology. CAS No. 7791-18-6. Pack Sizes: 10 g; 25 g. Product ID: HY-W019981B. | |
| Magnesium citrate | Magnesium citrate is a magnesium salt form that provides efficient penetration into brain and muscle tissue. Magnesium citrate increases pain threshold and reduces TLR4 concentration in the brain. Orally active [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Trimagnesium dicitrate. CAS No. 3344-18-1. Pack Sizes: 100 mg; 500 mg. Product ID: HY-W105835. | |
| Magnesium glycinate | Magnesium glycinate (Magnesium bisglycinate), the magnesium salt of glycine, is a nutrient supplement. Magnesium glycinate has satisfactory physico-chemical properties and bioactivities. Metal glycinate chelates are formed by glycine and metal compounds through chemical reactions. Magnesium is an essential mineral that plays a critical role in the human body. Magnesium takes part in the process of energy metabolism and assists the maintenance of normal muscle function [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Magnesium bisglycinate; Magnesium diglycinate. CAS No. 14783-68-7. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g; 10 g. Product ID: HY-129328. | |
| Magnesium isoglycyrrhizinate hydrate | Magnesium isoglycyrrhizinate hydrate is the active component found in licorice plant ( Glycyrrhiza glabra ). Magnesium isoglycyrrhizinate hydrate exhibits anti-inflammatory activity through NLRP3 inflammasome pathway, and attenuates the chronic obstructive pulmonary disease in rats [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 658701-67-8. Pack Sizes: 5 mg. Product ID: HY-154795. | |
| Magnesium Lithospermate B | Magnesium Lithospermate B, is a derivative of caffeic acid tetramer and an inhibitor of Na+/K+ ATPase , which can be extracted from Salviae miltiorrhizae. Magnesium Lithospermate B is widely used for the research of cardiovascular diseases, and it can protect against glucose-induced intracellular oxidative damage. Magnesium Lithospermate B also suppresses neuroin ammation and attenuates neurodegeneration [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 122021-74-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126415. | |
| Magnesium silicate | Magnesium silicate (Activated magnesium silicate) is an orally active compound composed of magnesium oxide (MgO) and silicon dioxide (SiO2). Magnesium silicate can be used in the preparation of food additives, antacids and anti-ulcer agents. Magnesium silicate is also a piezoelectric biomaterial, deodorant, decolorizing agent and antifungal agent [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Activated magnesium silicate. CAS No. 1343-88-0. Pack Sizes: 5 g. Product ID: HY-B2205. | |
| Magnesium sulfate | Magnesium sulphate is currently the anticonvulsant of choice for the prevention and control of eclamptic fits. Magnesium sulfate is also widely used as a tocolytic agent [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 7487-88-9. Pack Sizes: 50 g. Product ID: HY-Y1267. | |
| (+)-Magnoflorine chloride | Magnoflorine chloride (Magnoflorine chloride), an aporphine alkaloid found in Magnolia or Aristolochia, reduces the formation of C. albicans biofilm [1]. Magnoflorine chloride has anti-fungal, anti-antidiabetic and anti-oxidative activity [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Magnoflorine chloride; α-Magnoflorine chloride; Thalictrine chloride. CAS No. 6681-18-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N0535. | |
| (+)-Magnoflorine iodide | (+)-Magnoflorine iodide (Magnoflorine iodide), an aporphine alkaloid found in Acoruscalamus , reduces the formation of C. albicans biofilm [1]. (+)-Magnoflorine iodide has anti-fungal, anti-antidiabetic and anti-oxidative activity [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Magnoflorine iodide; α-Magnoflorine iodide; Thalictrine iodide. CAS No. 4277-43-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 20 mg. Product ID: HY-N0334A. | |
| Magnolol | Magnolol, a natural lignan isolated from the stem bark of Magnolia officinalis , is a dual agonist of both RXRα and PPARγ , with EC 50 values of 10.4 μM and 17.7 μM, respectively. Uses: Scientific research. Group: Natural products. CAS No. 528-43-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0163. | |
| Magrolimab | Magrolimab (Hu5F9-G4) is a humanized anti- CD47 antibody. Magrolimab can block the "don't eat me" signal of CD47 , thereby promoting macrophage mediated phagocytosis. Magrolimab has antitumor activity in malignant bone tumors and breast cancer [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Hu5F9-G4. CAS No. 2169232-81-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99029. | |
| MAHMA NONOate | MAHMA NONOate is a NO donor. MAHMA NONOate effectively inhibits platelet aggregation induced by either collagen or ADP [1]. Uses: Scientific research. Group: Natural products. CAS No. 146724-86-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-134216. | |
| MAK683 | MAK683 is an embryonic ectoderm development ( EED ) inhibitor extracted from patent US20160176882 A1, compound example 2. MAK683 exhibits IC 50 s of 59, 89, 26 nM in EED Alphascreen binding, LC-MS and ELISA assay [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1951408-58-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103663. | |
| Malabaricone C | Malabaricone C is an orally active and noncompetitive sphingomyelin synthase ( SMS ) inhibitor with IC 50 values of 3 μM and 1.5 μM for SMS 1 and SMS 2, respectively. Malabaricone C reduces body weight gain, improves glucose tolerance, and decreases lipid accumulation in the liver, showing significant prevention of high fat diet-induced fatty liver in mice. Malabaricone C has anti-inflammatory effects, which is found in the fruits of Myristica cinnamomea King. Malabaricone C is promising for research of obesity and immunological disorders caused due to hyper-activation of T-cells [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 63335-25-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N8518. | |
| Malachite green hemioxalate | Malachite green hemioxalate (MCCK1) is a triphenylmethane dye which can be used to detect the release of phosphate in enzymatic reactions. Malachite green hemioxalate has antibacterial activity, which is attributed to inhibition of intracellular enzymes, insertion into DNA and/or interaction with cell membranes. Malachite green hemioxalate is also a potent and selective inhibitor of IKBKE , and inhibits its downstream targets such as IκBα , p65 and IRF3. Malachite green hemioxalate exhibits antitumor activity in vitro and in vivo [1] [2] [3]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: MCCK1. CAS No. 2437-29-8. Pack Sizes: 100 mg. Product ID: HY-D0162. | |
| Mal-amido-PEG9-amine TFA | Mal-amido-PEG9-amine (TFA) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2569576-12-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-140976A. | |
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