MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Maribavir | Maribavir is a potent inhibitor of histone phosphorylation catalyzed by wild-type pUL97 in vitro, with an IC 50 of 3 nM. Maribavir has potent antiviral activity against HCMV and Epstein-Barr virus ( EBV ). Uses: Scientific research. Group: Signaling pathways. Alternative Names: 1263W94; BW1263W94; GW257406X. CAS No. 176161-24-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16305. |  |
| Maridebart | Maridebart is a human immunoglobulin G1-kappa, anti-GIPR (gastric inhibitory polypeptide receptor) monoclonal antibody [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: AMG133 antibody. CAS No. 2761478-99-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990047. | |
| Maridebart cafraglutide | Maridebart cafraglutide (AMG 133) is an antibody-peptide conjugate acting as a GLP-1 receptor agonist and an antagonist of the GIP receptor. Maridebart cafraglutide reduces body weight and improve metabolic markers in male obese mice and cynomolgus monkeys. Maridebart cafraglutide is promising for research of obesity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AMG 133. CAS No. 2887445-76-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-164535. | |
| Marimastat | Marimastat (BB2516) is a broad spectrum and orally bioavailable inhibitor of MMPs , with potent activity against MMP-9 ( IC 50 =3 nM), MMP-1 ( IC 50 =5 nM), MMP-2 ( IC 50 =6 nM), MMP-14 ( IC 50 =9 nM) and MMP-7 ( IC 50 =13 nM), used in the treatment of cancer. Marimastat (BB2516) is an angiogenesis and metastasis inhibitor, which limits the growth and production of blood vessels. As an antimetatstatic agent it prevents malignant cells from breaching the basement membranes [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BB2516; TA2516. CAS No. 154039-60-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-12169. | |
| Marizomib | Marizomib (Salinosporamide A) is a second-generation, irreversible, brain-penetrant, pan-proteasome inhibitor. Marizomib inhibits the CT-L (β5), CT-T-laspase-like (C-L, β1) and trypsin-like (T-L, β2) activities of the 20S proteasome (IC 50 =3.5, 28, and 430 nM, respectively) [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Salinosporamide A; NPI-0052. CAS No. 437742-34-2. Pack Sizes: 100 μg; 500 μg; 1 mg; 5 mg. Product ID: HY-10985. | |
| MARK-IN-1 | MARK-IN-1 is a potent microtubule affinity regulating kinase ( MARK ) inhibitor with an IC 50 of <0.25 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1109283-93-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-101933. | |
| MARK-IN-2 | MARK-IN-2 is a potent microtubule affinity regulating kinase ( MARK ) inhibitor with an IC 50 of 5 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1314893-26-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101934. | |
| (±)-Marmesin | (±)-Marmesin is a good precursor of the linear furanocoumarins. (±)-Marmesin derivatives have high degree of acetylcholinesterase inhibitory property [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 13710-70-8. Pack Sizes: 1 mg. Product ID: HY-N2176A. | |
| Maropitant | Maropitant is a selective and orally active neurokinin (NK1) receptor antagonist. Maropitant acts by blocking the binding of substance P within the emetic center and the chemoreceptor trigger zone (CRTZ). Maropitant is highly effective in preventing vomiting [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 147116-67-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10053. | |
| Marrubiin | Marrubiin, isolated from Marrubium vulgare , exhibits vasorelaxant and antioedematogenic activity. Marrubiin alleviates diabetic symptoms in animals [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 465-92-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N6995. | |
| Marstacimab | Marstacimab (PF-06741086) is an anti-tissue factor pathway inhibitor ( TFPI ) monoclonal antibody. Marstacimab can be used for the research of hemophilia [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: PF-06741086. CAS No. 1985638-39-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99725. | |
| MART-1 (26-35) (human) | MART-1 (26-35) (human) is amino acid residue 26 to 35 of MART-1 protein. Uses: Scientific research. Group: Peptides. CAS No. 156251-01-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0138. | |
| Masitinib | Masitinib (AB1010) is a potent, orally bioavailable, and selective inhibitor of c-Kit ( IC 50 =200 nM for human recombinant c-Kit). It also inhibits PDGFRα/β ( IC 50 s=540/800 nM), Lyn ( IC 50 = 510 nM for LynB), Lck , and, to a lesser extent, FGFR3 and FAK. Masitinib (AB1010) has anti-proliferative, pro-apoptotic activity and low toxicity [1] [2] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AB1010. CAS No. 790299-79-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10209. | |
| Masitinib mesylate | Masitinib mesylate (AB-1010 mesylate) is a potent, orally bioavailable, and selective inhibitor of c-Kit ( IC 50 =200 nM for human recombinant c-Kit). It also inhibits PDGFRα/β ( IC 50 s=540/800 nM), Lyn ( IC 50 = 510 nM for LynB), Lck , and, to a lesser extent, FGFR3 and FAK. Masitinib mesylate (AB-1010 mesylate) has anti-proliferative, pro-apoptotic activity and low toxicity [1] [2] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AB-1010 mesylate. CAS No. 1048007-93-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10209A. | |
| Maslinic acid | Maslinic acid can inhibit the DNA-binding activity of NF-κB p65 and abolish the phosphorylation of IκB-α , which is required for p65 activation. Uses: Scientific research. Group: Natural products. Alternative Names: Crategolic acid; 2α-Hydroxyoleanolic acid. CAS No. 4373-41-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-N0629. | |
| Masofaniten | Masofaniten (Androgen receptor-IN-2) is a potent and orally active androgen receptor inhibitor. Masofaniten has antitumor activity against prostate cancer [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Androgen receptor-IN-2. CAS No. 2416716-62-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136582. | |
| Masoprocol | Masoprocol (meso-Nordihydroguaiaretic acid) is a potent and orally active lipoxygenase inhibitor. Masoprocol shows antihyperglycemic activity. Masoprocol decreases the glucose concentration and hepatic triglyceride in vivo. Masoprocol has the potential for the research of type II diabetes [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: meso-Nordihydroguaiaretic acid; meso-NDGA. CAS No. 27686-84-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-109500. | |
| Massoia lactone | Massoia lactone ((±)-Massoia lactone) is a coconut and creamy fragrant compound mianly isolated from Cryptocarya massoy. Massoia lactone is also a fragrant biosurfactant produced by a fungus Aureobasidium pullulans [1]. Uses: Scientific research. Group: Natural products. Alternative Names: (±)-Massoia lactone. CAS No. 54814-64-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 5 g; 10 g; 25 g. Product ID: HY-N7435. | |
| Mastoparan | Mastoparan, a tetradecapeptide which is a component of wasp venom, stimulates release of prolactin from cultured rat anterior pituitary cells. Uses: Scientific research. Group: Peptides. CAS No. 72093-21-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0246. | |
| Mastoparan X | Mastoparan X is a GTP-binding regulatory protein ( G protein )-activating peptide, and a tetradecapeptide from wasp venom. Mastoparan X acts function by the direct activation of G protein that couple to phospholipase C to cause secretion from various kinds of cells [1]. Uses: Scientific research. Group: Peptides. CAS No. 72093-22-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P2705. | |
| Masupirdine mesylate | Masupirdine mesylate (SUVN-502 mesylate) is a potent, selective, orally bioavailable, and brain penetrant 5-HT6 receptor antagonist ( K i of 2.04 nM for human 5-HT6 receptor). Masupirdine mesylate (SUVN-502 mesylate) shows high selectivity over 5-HT2A receptor and other 100 target sites, and has potential for treatment of Alzheimer's disease [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SUVN-502 mesylate. CAS No. 1791396-46-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109118A. | |
| MAT2A inhibitor 2 | MAT2A inhibitor 2 is an inhibitor of methionine adenosine transferase 2A ( MAT2A ) with oral activity. MAT2A inhibitor 2 can be used in osteoporosis study [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 13299-99-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112569. | |
| Matairesinol | Matairesinol confers anti-allergic effects in an allergic dermatitis mouse model. DfE-induced changes in IL-4 and IFN-γ mRNA expression in the ears of NC/Nga mice were reversed by matairesinol application [1]. Uses: Scientific research. Group: Natural products. CAS No. 580-72-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N3312. | |
| Matrine | Matrine (Matridin-15-one) is an alkaloid found in plants from the Sophora genus that can act as a kappa opioid receptor and u-receptor agonist. Matrine has a variety of pharmacological effects, including anti-cancer, anti-oxidative stress, anti-inflammation and anti-apoptosis effects. Matrine is potential in the research of disease like human non-small cell lung cancer, hepatoma, papillary thyroid cancer and acute kidney injury (AKI) [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. Alternative Names: Matridin-15-one; Vegard; α-Matrine. CAS No. 519-02-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg. Product ID: HY-N0164. | |
| Matriptase-IN-2 | Matriptase-IN-2 (compound 432) is a potent Matriptase inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1268874-09-4. Pack Sizes: 5 mg. Product ID: HY-W783268A. | |
| Matuzumab | Matuzumab (EMD 72000) is a humanized anti- EGFR monoclonal antibody that blocks EGFR activation and downstream signaling, inhibits tumor growth [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: EMD 72000. CAS No. 339186-68-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9969. | |
| Mavacamten | Mavacamten (MYK461) is an orally active modulator of cardiac myosin , with IC 50 s of 490, 711 nM for bovine cardiac and human cardiac, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MYK461; SAR439152. CAS No. 1642288-47-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109037. | |
| Mavacoxib | Mavacoxib is a selective, oral long-acting cyclooxygenase-2 (COX-2) inhibitor and a long-acting non-steroidal anti-inflammatory drug (NSAID). Mavacoxib is used to treat pain and inflammation associated with degenerative joint disease in dogs [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 170569-88-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-119447. | |
| Mavoglurant | Mavoglurant (AFQ056) is a potent, selective, non-competitive and orally active mGluR5 antagonist, with an IC 50 of 30 nM. Mavoglurant shows a >300 fold selectivity for the mGluR5 over all targets (238) tested. Mavoglurant can be used for the research of Fragile X syndrome (FXS), and L-dopa induced dyskinesias in Parkinson's disease [1] [1] [2]. Mavoglurant is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AFQ056. CAS No. 543906-09-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15257. | |
| Mavoglurant racemate | Mavoglurant racemate (AFQ-056 racemate) is the racemate of Mavoglurant. Mavoglurant is a novel, non-competitive mGlu5 receptor antagonist [1]. Mavoglurant (racemate) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AFQ-056 racemate. CAS No. 1636881-61-2. Pack Sizes: 2 mg; 5 mg. Product ID: HY-15257A. | |
| Mavorixafor hydrochloride | Mavorixafor (AMD-070) hydrochloride is a potent, selective and orally available CXCR4 antagonist, with an IC 50 value of 13 nM against CXCR4 125 I-SDF binding. Mavorixafor hydrochloride also inhibits the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells and PBMCs with an IC 50 of 1 nM and 9 nM, respectively. Mavorixafor hydrochloride can be used for the study of WHIM syndrome [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AMD-070 hydrochloride; AMD-11070 hydrochloride. CAS No. 880549-30-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-50101C. | |
| Mavrilimumab | Mavrilimumab (CAM 3001) is a monoclonal antibody that binds to the α subunit of the granulocyte-macrophage colony stimulating factor ( GM-CSF ) receptor and blocks intracellular signalling downstream of GM-CSF. GM-CSF might be a mediator of the hyperactive inflammatory response associated with respiratory failure and death [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: CAM 3001. CAS No. 1085337-57-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99031. | |
| MAX-40279 | MAX-40279 is a dual and potent inhibitor of FLT3 kinase and FGFR kinase. MAX-40279 has the potential for the research of acute myelogenous leukemia (AML) (extracted from patent WO2021180032) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2070931-57-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145723. | |
| Maxacalcitol | Maxacalcitol (22-Oxacalcitriol), a vitamin D3 (HY-15398) analog, is an orally active VDR agonist. Maxacalcitol has a limited calcemic effect. Maxacalcitol has the potential for psoriasis and hyperparathyroidism research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 22-Oxacalcitriol. CAS No. 103909-75-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-32339. | |
| Maytansine | Maytansine is a highly potent microtubule-targeted compound that induces mitotic arrest and kills tumor cells at subnanomolar concentrations [1]. Uses: Scientific research. Group: Natural products. Alternative Names: NSC 153858. CAS No. 35846-53-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-13674. | |
| Mazdutide | Mazdutide (IBI-362; LY-3305677) is a long-acting synthetic oxyntomodulin analog. Mazdutide is also a co-agonist of glucagon-like peptide ( GLP-1R ) and glucagon receptor ( GCGR ). Mazdutide binds human and mouse GCGR ( K i : 17.7 nM and 15.9 nM, respectively) and GLP-1R ( K i : 28.6 nM and 25.1 nM, respectively) and stimulates insulin secretion from mouse islets ( EC 50 : 5.2 nM). Mazdutide is used in studies of obesity and type 2 diabetes (T2D) [1] [2] [3]. Uses: Scientific research. Group: Peptides. Alternative Names: IBI-362; LY-3305677; OXM-3. CAS No. 2259884-03-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P3375. | |
| Mazisotine | SSTR4 agonist-1 (Compound 47) is a selective agonist for somatostatin receptor subtype 4 ( SSTR4 ) with an EC 50 of 4.7 nM. SSTR4 agonist-1 reveals a half-life > 130 minutes in human liver microsomes [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1638588-92-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139347. | |
| MB710 | MB710, an aminobenzothiazole derivative, is a stabilizer of oncogenic p53 mutation Y220C. MB710 binds tightly to the Y220C pocket and stabilizes p53-Y220C , with a K d of 4.1?μM. MB710 shows anticancer activity in p53-Y220C cell lines [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2230044-57-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-120373. | |
| MBD | MBD (7-(p-Methoxybenzylamino)-4-nitrobenz-2,1,3-oxadiazole), a new fluorescent probe for protein and nucleoprotein conformation, is applied to bacterial ribosomes and to bovine trypsinogen and trypsin. MBD is strongly fluorescent upon binding to a hydrophobic area of a macromolecule [1] [2]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: 7-(p-Methoxybenzylamino)-4-nitrobenz-2,1,3-oxadiazole. CAS No. 33984-50-8. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-141667. | |
| MBX-2982 | MBX-2982 is a selective, orally-available G protein-coupled receptor 119 ( GPR119 ) agonist. Uses: Scientific research. Group: Signaling pathways. CAS No. 1037792-44-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15291. | |
| MC70 | MC70 is a potent and non-selective P-glycoprotein (P-gp) inhibitor with an EC 50 of 0.69 μM. MC70 is an ABC transporters inhibitor and anticancer agent. MC70 interacts with ABCB1, ABCG2 and ABCC1 [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1031367-64-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113805. | |
| MCA | MCA is a coumarin derivative. MCA quantitates platelet-activating factor by high-performance liquid chromatography with fluorescent detection. MCA can modify FRET peptide substrates for analyzing protease activities [1] [2]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 62935-72-2. Pack Sizes: 100 mg; 250 mg; 500 mg. Product ID: HY-W027544. | |
| MC-AAA-NHCH2OCH2COOH | MC-AAA-NHCH2OCH2COOH (compound 20) is a cleavable ADC linker that is used for making antibody-drug conjugate (ADC) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2414594-28-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132159. | |
| Mca-SEVNLDAEFK(Dnp)-NH2 | Mca-SEVNLDAEFK(Dnp)-NH2 contains a highly fluorescent 7-methoxycoumarin group that is efficiently quenched by resonance energy transfer to the 2,4-dinitrophenyl group. It can be used to measure the activities of peptidases that are capable of cleaving an amide bond between the fluorescent group and the quencher group, causing an increase in fluorescence, such as can be used to measure the activity of BACE-1 [1]. Uses: Scientific research. Group: Peptides. CAS No. 1802078-32-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P4920. | |
| MCB-613 | MCB-613 is a potent Steroid receptor coactivator SRC small molecule stimulator (SMS), super-stimulates SRCs transcriptional activity. MCB-613 increases SRCs interactions with other coactivators and markedly induces ER stress coupled to the generation of reactive oxygen species ( ROS ). MCB-613 is a SMS that target oncogenes can be exploited as anti-cancer agents by over-stimulating the SRC oncogenic program [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1162656-22-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19625. | |
| MCC | MCC is non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as MCC-DM1 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 104676-09-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132251. | |
| MCC950 | MCC950 (CP-456773; CRID3) is a potent and selective NLRP3 inhibitor with IC 50 s of 7.5 and 8.1 nM in BMDMs and HMDMs, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CP-456773; CRID3. CAS No. 210826-40-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12815. | |
| MCC950 sodium | MCC950 sodium (CP-456773 sodium; CRID3 sodium salt) is a potent, selective NLRP3 inhibitor with IC 50 s of 7.5 and 8.1 nM in BMDMs and HMDMs, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CP-456773 sodium; CRID3 sodium salt. CAS No. 256373-96-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-12815A. | |
| MC-DOXHZN hydrochloride | MC-DOXHZN ((E/Z)-Aldoxorubicin) hydrochloride is an albumin-binding proagent of Doxorubicin (DNA topoisomerase II inhibitor), with acid-sensitive properties [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (E/Z)-Aldoxorubicin hydrochloride; Doxorubicin(6-maleimidocaproyl)hydrazone hydrochloride. CAS No. 480998-12-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-16261B. | |
| MCL-1/BCL-2-IN-2 | MCL-1/BCL-2-IN-2 (Compound 6) is a potent and selective Mcl-1 and Bcl-2 dual inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2163793-44-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-129700. | |
| MCL-1/BCL-2-IN-3 | MCL-1/BCL-2-IN-3 (Compound 2) is a potent and selective Mcl-1 and Bcl-2 dual inhibitor with IC 50 s of 5.95 and 4.78 μM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2163793-55-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129701. | |
| Mcl1-IN-1 | Mcl1-IN-1 is an inhibitor of myeloid cell factor 1 ( Mcl-1 ) ( IC 50 =2.4 μM). Uses: Scientific research. Group: Signaling pathways. CAS No. 713492-66-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16669. | |
| MCLA hydrochloride | MCLA hydrochloride is a chemiluminescent reagent which can be used to quantify aqueous concentrations of superoxide. Uses: Scientific research. Group: Fluorescent dye. CAS No. 128322-44-1. Pack Sizes: 5 mg. Product ID: HY-W013275. | |
| McN-A-343 | McN-A-343 is a selective M1 muscarinic agonist that stimulates muscarinic transmission in sympathetic ganglia. McN-A-343 reduces inflammation and oxidative stress in an experimental model of ulcerative colitis [1] [2]. McN-A-343 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 55-45-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107648. | |
| m-Coumaric acid | m-Coumaric acid is a polyphenol metabolite from caffeic acid, formed by the gut microflora and the amount in human biofluids is diet-dependant. Uses: Scientific research. Group: Natural products. CAS No. 588-30-7. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-113357. | |
| MCPA | MCPA is a phenoxy herbicide, and widely used to control annual and perennial broad leaved weeds, including poppy, thistles and docks, in crops such as cereals, rice, linseed, flax, grassland and turf [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 94-74-6. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-B0859. | |
| MCTR3 | MCTR3 is a potent cytokine of pro-resolving mediating maresin conjugates in tissue regeneration (MCTR), which reduces the inflammatory response and promotes the tissue regeneration. MCTR3 exhibits potency in ameliorating LPS-induced acute lung injury and arthritis [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1784701-63-8. Pack Sizes: 10 μg (215.69 μM * 100 μL in Ethanol)); 25 μg (215.69 μM * 250 μL in Ethanol). Product ID: HY-125516. | |
| MDA 19 | MDA 19 is a potent and selective agonist of human cannabinoid receptor 2 (CB2) , with a K i of 43.3 nM. MDA 19 has antiallodynic effects in a rat model of neuropathic pain and does not affect rat locomotor activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1048973-47-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15451. | |
| Mdivi-1 | Mdivi-1 is a selective dynamin-related protein 1 ( Drp1 ) inhibitor. Mdivi-1 is a mitochondrial division/ mitophagy inhibitor. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Mitochondrial division inhibitor 1. CAS No. 338967-87-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15886. | |
| MDL12330A | MDL12330A (RMI12330A) is an adenyl cyclase inhibitor. MDL12330A inhibits the vasopressin action on the short-circuit current (SCC). MDL12330A is also an inhibitor of cAMP phosphodiesterase [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RMI12330A. CAS No. 40297-09-4. Pack Sizes: 5 mg. Product ID: HY-103192. | |
| MDL-28170 | MDL-28170 (Calpain Inhibitor III) is a potent, selective and membrane-permeable cysteine protease inhibitor of calpain that rapidly penetrates the blood-brain barrier following systemic administration [1] [2]. MDL-28170 also block γ-secretase [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Calpain Inhibitor III. CAS No. 88191-84-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18236. | |
| MDL 72527 | MDL 72527 is a potent polyamine oxidase (PAO) inhibitor. MDL 72527 shows a lysosomotropic effect. MDL 72527 shows neuroprotective effects [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 93565-01-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100621. | |
| ME0328 | ME0328 is a potent and selective ARTD3 / PARP3 inhibitor with an IC 50 of 0.89±0.28 μM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1445251-22-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100225. | |
| ME-344 | ME-344 is a mitochondrial inhibitor. ME-344 has significant biological antitumor activity in HER2-negative breast cancer [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1374524-68-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112749. | |
| Mead acid | Mead acid (5,8,11-Eicosatrienoic acid), an unsaturated (Omega-9) fatty acid, is an indicator of essential fatty acid deficiency [1]. Uses: Scientific research. Group: Natural products. Alternative Names: 5,8,11-Eicosatrienoic acid. CAS No. 20590-32-3. Pack Sizes: 1 mg (32.63 mM * 100 μL in Ethanol). Product ID: HY-108398A. | |
| Mebendazole | Mebendazole is a highly effective, broad-spectrum antihelmintic against nematode infestations. Mebendazole also exhibits inhibitory effect against glioblastoma multiforme (GBM), inhibits Hedgehog pathway and tubulin polymerization. Mebendazole is orally active and can cross CNS penetration [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 31431-39-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-17595. | |
| Mebeverine hydrochloride | Mebeverine hydrochloride, a β-phenylethylamine derivative, is a musculotropic agent that potently blocks intestinal peristalsis. Mebeverine directly blocks voltage-operated sodium channels and inhibits intracellular calcium accumulation [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2753-45-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0078. | |
| Mebhydrolin | Mebhydrolin is a specific histamine H 1 receptor antagonist. Uses: Scientific research. Group: Signaling pathways. CAS No. 524-81-2. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B1303A. | |
| Mebhydrolin napadisylate | Mebhydrolin napadisylate is a specific histamine H 1 receptor antagonist. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Mebhydroline 1,5-naphthalenedisulfonate salt. CAS No. 6153-33-9. Pack Sizes: 50 mg. Product ID: HY-B1303. | |
| Mebrofenin | Mebrofenin (SQ 26962) is a type of iminodiacetic acid (IDA). Mebrofenin is available as a ready to use the kit for radio-labeling with Tc-99m. Tc-99m Mebrofenin, a diagnostic agent, is used for hepatobiliary imaging. Tc-99m Mebrofenin is the radiopharmaceutical of choice for the evaluation of hepatic function [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: SQ 26962. CAS No. 78266-06-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1684. | |
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