MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Inclacumab | Inclacumab (Anti-Human selectin P Recombinant Antibody) is a human monoclonal IgG4 antibody selectively targets P-selectin with a K d value of 9.9 nM. Inclacumab inhibits P-selectin glycoprotein ligand 1 (PSGL-1) mimetic peptide bind with P-selectin with an IC 50 value of 1.9 μg/mL and strongly inhibits cell adhesion [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-Human selectin P Recombinant Antibody. CAS No. 1256258-86-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99263. |  |
| Inclisiran sodium | Inclisiran sodium is a double-stranded small interfering RNA (siRNA) molecule. Inclisiran sodium inhibits the transcription of PCSK9. Inclisiran sodium inhibits Pyroptosis, activates PPAR?, and reduces NLRP3, cleaved caspase-1, IL-1?, and IL-18. Inclisiran sodium has anti-inflammatory, lipid-regulating and anti-atherosclerotic activities. Inclisiran sodium can be used in researches of hyperlipidemia and cardiovascular disease (CVD)[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ALN-PCSsc sodium. Pack Sizes: 1 mg; 5 mg. Product ID: HY-132591A. | |
| Incomplete Freund's adjuvant (IFA) | Incomplete Freund's adjuvant (IFA) (Montanide ISA-51) is an immunoadjuvant emulsified with antigen by its discoverer Jules T. Freund. Incomplete Freund's adjuvant (IFA) does not contain inactivated tuberculosis bacilli and consists of petroleum jelly containing lanolin. Incomplete Freund's adjuvant (IFA) induces high antibody titers and long-lasting effector T cell responses with no long-term effects on collagen disease, tumors, or death. Complete Freund's adjuvant (CFA) (HY-153808) is another type of Freund's Adjuvant that stimulates a stronger immune response[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Montanide ISA-51. Pack Sizes: 10 mL; 10 mL * 2; 10 mL * 5. Product ID: HY-153808A. | |
| Incyclinide | Incyclinide (CMT-3, COL-3) is a matrix metalloproteinase ( MMP ) inhibitor and inhibiting angiogenesis, tumor growth and invasion, and metastasis. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CMT-3; COL-3. CAS No. 15866-90-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13648. | |
| Indacaterol | Indacaterol is an orally active ultra-long-acting β2 adrenergic receptor ( ADRB2 ) agonist. Indacaterol inhibits NF-κB activity in a β-arrestin2 -dependent manner, preventing further lung damage and improving lung function in COPD (chronic obstructive pulmonary disorder). Indacaterol can also be used in cardiovascular disease research [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 312753-06-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-14299. | |
| Indacaterol maleate | Indacaterol maleate (QAB149) is an orally active ultra-long-acting β2 adrenergic receptor ( ADRB2 ) agonist. Indacaterol maleate inhibits NF-κB activity in a β-arrestin2 -dependent manner, preventing further lung damage and improving lung function in COPD (chronic obstructive pulmonary disorder). Indacaterol maleate can also be used in cardiovascular disease research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: QAB149. CAS No. 753498-25-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-14299A. | |
| Indacaterol (maleate) (Standard) | Indacaterol (maleate) (Standard) is the analytical standard of Indacaterol (maleate). This product is intended for research and analytical applications. Indacaterol maleate (QAB149) is an orally active ultra-long-acting β2 adrenergic receptor ( ADRB2 ) agonist. Indacaterol maleate inhibits NF-κB activity in a β-arrestin2 -dependent manner, preventing further lung damage and improving lung function in COPD (chronic obstructive pulmonary disorder). Indacaterol maleate can also be used in cardiovascular disease research [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 753498-25-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14299AR. | |
| Indapamide | Indapamide is an orally active sulphonamide diuretic agent, that can reduce blood pressure by decreasing vascular reactivity and peripheral vascular resistance. Indapamide is also can reduce left ventricular hypertrophy [1] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 26807-65-8. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0259. | |
| Indatuximab | Indatuximab is a CHO-expressed, VHH-Fc (huIgG1) type chimeric antibody that targets Syndecan-1/CD138. The predicted molecular weight (MW) of Indatuximab is 146.1 kDa. The isotype control for Indatuximab can refer to Human IgG4 kappa, Isotype Control (HY-P99003). Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1238517-16-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990607. | |
| Indatuximab ravtansine | Indatuximab ravtansine (BT-062) is an antibody-drug conjugate (ADC) ( Antibody-Drug Conjugates (ADCs) ) based on a murine/human chimeric form of B-B4 (specific for CD138), linked to the maytansinoid agent DM4 by disulphide bonds. Indatuximab ravtansine shows anti-tumor activities [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BT-062; nBT062-DM4. CAS No. 1238517-16-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-141607. | |
| Indazole | Indazole, also called isoindazole, a heterocyclic aromatic organic compound. Its derivatives display a broad variety of biological activities including anti-inflammatory, antibacterial, anti-HIV, antiarrhythmic, antifungal and antitumour properties. Indazole and its derivatives can be used for research of cancer, neurological disorders, cardiovascular diseases, gastrointestinal diseases [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 271-44-3. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-40294. | |
| Indazole-3-carboxylic acid | Indazole-3-carboxylic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 4498-67-3. Pack Sizes: 25 g. Product ID: HY-W002518. | |
| Indeno[1,2,3-cd]pyrene | Indeno[1,2,3-cd]pyrene is a polycyclic aromatic hydrocarbon with moderate cytotoxicity in human pulmonary alveolar epithelial cells HPAEpiC. Indeno[1,2,3-cd]pyrene enhances allergic lung infammation via aryl hydrocarbon receptor [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 193-39-5. Pack Sizes: 1 mg (4.08 μg/mL * 1 mL in Methanol). Product ID: HY-23499. | |
| Indibulin | Indibulin (ZIO 301), an orally applicable inhibitor of tubulin assembly, shows potent anticancer activity with a minimal neurotoxicity. Indibulin reduces inter-kinetochoric tension, produces aberrant spindles, activates mitotic checkpoint proteins Mad2 and BubR1, and induces mitotic arrest and apoptosis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ZIO 301; D 24851. CAS No. 204205-90-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13649. | |
| Indican | Indican (Indoxyl-β-D-glucoside), a glycoside of indoxyl, is a precursor of the dyesindigo and indirubin. Indican has a major metabolite, indoxyl sulfate (IS). IS, an uremic toxin, is a substrate/inhibitor of organic anion transporter (OAT) 1, OAT 3 and multidrug resistance-associated protein (MRP) 4 [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Indoxyl-β-D-glucoside. CAS No. 487-60-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-122009. | |
| Indigo | Indigo is a deep and rich color dye for indole stain, isolated from the plant Indigofera tinctoria and related species [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 482-89-3. Pack Sizes: 100 mg; 1 g. Product ID: HY-N0335. | |
| Indigo carmine | Indigo carmine is an efficient reagent for the determination of ozone by chemlluminescence (CL) [1]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Indigotindisulfonate sodium; C.I.Acid Blue 74. CAS No. 860-22-0. Pack Sizes: 500 mg. Product ID: HY-W040226. | |
| Indinavir | Indinavir (MK-639 free base) is an orally active and selective HIV-1 protease inhibitor with a K i of 0.54 nM for PR. Indinavir exhibits anticancer activity by inhibiting the activation of MMPs-2 hydrolysis, anti-angiogenesis and inducing apoptosis. Indinavir is also a SARS-CoV 3CL pro inhibitor [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-639 free base; L-735524 free base. CAS No. 150378-17-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-B0689. | |
| Indinavir sulfate | Indinavir sulfate (MK-639) is an orally active and selective HIV-1 protease inhibitor with a K i of 0.54 nM for PR. Indinavir sulfate exhibits anticancer activity by inhibiting the activation of MMPs-2 hydrolysis, anti-angiogenesis and inducing apoptosis. Indinavir sulfate is also a SARS-CoV 3CL pro inhibitor [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-639; L735524. CAS No. 157810-81-6. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B0689A. | |
| Indirubin | Indirubin (Couroupitine B) is a bis-indole alkaloid and has emarkable anticancer activity against chronic myelocytic leukemia [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Couroupitine B; Indigo red; Indigopurpurin. CAS No. 479-41-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-N0117. | |
| Indirubin-3'-monoxime | Indirubin-3'-monoxime is a potent GSK-3β inhibitor, and weakly inhibits 5-Lipoxygenase , with IC 50 s of 22 nM and 7.8-10 μM, respectively; Indirubin-3'-monoxime also shows inhibitory activities against CDK5/p25 and CDK1/cyclin B, with IC 50 s of 100 and 180 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Indirubin-3'-oxime. CAS No. 160807-49-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-19807. | |
| Indisulam | Indisulam (E 7070) is a carbonic anhydrase inhibitor with anticancer activity. Indisulam (E 7070) is a sulfonamide agent that targets the G1 phase of the cell cycle. Indisulam (E 7070) causes a blockade in the G1/S transition through inhibition of the activation of both CDK2 and cyclin E. Indisulam (E 7070) targets splicing by inducing RBM39 degradation via recruitment to DCAF15 [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: E 7070. CAS No. 165668-41-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-13650. | |
| Indo-1 AM | Calcium is an important part of the human body, usually in the form of calcium, a large number of bones and teeth of the human body, a small amount of blood and tissues. MCE calcium ion detection probe can specifically identify intracellular calcium ions, with high sensitivity, low cytotoxicity, increased AM acetylmethyl ester can enter the cell well, after being sheared by the intracellular esterase stay in the cell to bind to calcium ions, produce strong fluorescence, in addition, Mag-indo-1/AM and Mag-Fluo-4 AM at a certain concentration (usually 5 mM) can effectively identify intracellular magnesium ions [1]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Indo-1 Acetoxymethyl ester. CAS No. 112926-02-0. Pack Sizes: 1 mg. Product ID: HY-101898. | |
| Indobufen | Indobufen is a platelet aggregation inhibitor. Indobufen is a reversible platelet cyclooxygenase ( Cox ) activity inhibitor. Indobufen suppresses thromboxane A 2 (TxA 2 ) synthesis. Indobufen down-regulates tissue factor (TF) in monocytes [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ibustrin. CAS No. 63610-08-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18763. | |
| Indocyanine green | Indocyanine green (Foxgreen) is a low toxicic fluorescent agent that has been widely used in medical diagnostics, such as determining cardiac output, hepatic function, and liver blood flow, and for ophthalmic angiography [1]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Foxgreen; IC Green; Cardiogreen. CAS No. 3599-32-4. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-D0711. | |
| (-)-Indolactam V | (-)-Indolactam V is a PKC activator, with K i s of 3.36 nM, 1.03 μM for η-CRD2 (PKCη surrogate peptide), γ-CRD2 (PKCγ surrogate peptide), and K d s of 5.5 nM (η-C1B), 7.7 nM (ε-C1B), 8.3 nM (δ-C1B), 18.9 nM (β-C1A-long), 20.8 nM (α-C1A-long), 137 nM (β-C1B), 138 nM (γ-C1A), 213 nM (γ-C1B), and has antitumor activity. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Indolactam V. CAS No. 90365-57-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12307. | |
| Indole | Indole is an aromatic, heterocyclic, organic compound which widely distributed in the natural environment and can be produced by a variety of bacteria. Indole regulates various aspects of bacterial physiology, including spore formation, plasmid stability, resistance to drugs, biofilm formation, and virulence as an intercellular signal molecule [1]. Uses: Scientific research. Group: Natural products. CAS No. 120-72-9. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-W001132. | |
| Indole-2-carbaldehyde | 1H-Indole-2-carbaldehyde is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 19005-93-7. Pack Sizes: 1 g; 5 g. Product ID: HY-W015650. | |
| Indole-2-carboxylic acid | Indole-2-carboxylic acid is a strong inhibitor of lipid peroxidation. Indole-2-carboxylic acid (I2CA) specifically and competitively inhibits the potentiation by glycine of NMDA -gated current [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 1477-50-5. Pack Sizes: 10 mM * 1 mL; 5 g; 10 g; 25 g. Product ID: HY-I0096. | |
| Indole-3-acetamide | Indole-3-acetamide is a biosynthesis intermediate of indole-3-acetic acid (HY-18569). Indole-3-acetic acid is the most common natural plant growth hormone of the auxin class [1]. Uses: Scientific research. Group: Natural products. CAS No. 879-37-8. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-W016784. | |
| Indole-3-acetylglycine | Indole-3-acetylglycine is a biochemical assay reagent. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 13113-08-1. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-W317414. | |
| Indole-3-butyric acid | Indole-3-butyric acid (3-indolebutyric acid) is a plant growth auxin and a good rooting agent. It can promote herbs and woody ornamental plant rooting and used for improving fruit rate. Indole 3-butyric acid is an auxin precursor, and is converted to indole 3-acetic acid (IAA) in a peroxisomal β-oxidation process [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Indolebutyric acid. CAS No. 133-32-4. Pack Sizes: 10 mM * 1 mL; 5 g; 10 g. Product ID: HY-N0186. | |
| Indole-3-butyric acid (Standard) | Indole-3-butyric acid (Standard) is the analytical standard of Indole-3-butyric acid. This product is intended for research and analytical applications. Indole-3-butyric acid (3-indolebutyric acid) is a plant growth auxin and a good rooting agent. It can promote herbs and woody ornamental plant rooting and used for improving fruit rate. Indole 3-butyric acid is an auxin precursor, and is converted to indole 3-acetic acid (IAA) in a peroxisomal β-oxidation process [1]. Uses: Scientific research. Group: Natural products. CAS No. 133-32-4. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-N0186R. | |
| Indole-3-carbinol | Indole-3-carbinol (I3C) inhibits NF-κB activity and also is an Aryl hydrocarbon receptor ( AhR ) agonist, and an inhibitor of WWP1 (WW domain-containing ubiquitin E3 ligase 1). Uses: Scientific research. Group: Natural products. Alternative Names: Indole-3-methanol. CAS No. 700-06-1. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g; 10 g. Product ID: HY-N0170. | |
| Indole-3-carboxaldehyde | Indole-3-carboxaldehyde (3-Formylindole), a banlangen extract, is the product of the oxidative degradation of indole-3-acetic acid (IAA) by crude enzyme preparations from etiolated pea seedlings. Indole-3-carboxaldehyde is a biochemical used to prepare analogs of the indole phytoalexin cyclobrassinin. Indole-3-carboxaldehyde also enhances the epithelial barrier and anti-inflammatory activity in the intestinal tract [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: 3-Formylindole. CAS No. 487-89-8. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-W007376. | |
| Indole-3-carboxylic acid | Indole-3-carboxylic acid is an orally active urinary indolic tryptophan metabolite. Indole-3-carboxylic acid is a mediator of priming against Plectosphaerella cucumerina. Indole-3-carboxylic acid enhances the anti-colorectal cancer potency of Doxorubicin (HY-15142A) by inducing cell senescence. Indole-3-carboxylic acid can be used in liver disease research [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 771-50-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-40161. | |
| Indole-3-carboxylic acid (Standard) | Indole-3-carboxylic acid (Standard) is the analytical standard of Indole-3-carboxylic acid. This product is intended for research and analytical applications. Indole-3-carboxylic acid is a normal urinary indolic tryptophan metabolite and has been found elevated in patients with liver diseases [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 771-50-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-40161R. | |
| Indole-3-methanamine | Indole-3-methanamine is a potential biomarker for the consumption of these foods such as barley, cereals, and cereal product [1]. Uses: Scientific research. Group: Natural products. CAS No. 22259-53-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-33893. | |
| Indole-3-pyruvic acid | Indole-3-pyruvic acid, a keto analogue of tryptophan, is an orally active AHR agonist. Indole-3-pyruvic acid has antioxidant properties, and can be used in the research of inflammation, anxiety [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 392-12-1. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-W028393. | |
| Indole-4-carboxaldehyde | 1H-Indole-4-carbaldehyde is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 1074-86-8. Pack Sizes: 5 g; 10 g. Product ID: HY-W001288. | |
| Indole-5-carboxylic acid, 98% | Indole-5-carboxylic acid, 98% is an oxytocin that interacts with serotonin receptors and gamma-aminobutyric acid (GABA) receptors. It has also been reported to interact with various enzymes such as cyclooxygenase-2 (COX-2) and 5-hydroxytryptamine (5-HT) receptors. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 1670-81-1. Pack Sizes: 5 g. Product ID: HY-59302. | |
| Indole-d7 | Indole-d7 is the deuterium labeled Indole[1]. Indole is an endogenous metabolite. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 73509-20-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W001132S4. | |
| Indolelactic acid | Indolelactic acid (Indole-3-lactic acid) is a tryptophan (Trp) catabolite in Azotobacter vinelandii cultures. Indolelactic acid has anti-inflammation and potential anti-viral activity [1] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Indole-3-lactic acid. CAS No. 1821-52-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113099. | |
| Indoline | Indoline is a derivative of Indole (HY-W001132). Indoline can used as the basic structure for CD4 mimetic compounds (CD4mcs), which triggers conformational changes of the HIV-1 envelope glycoprotein (Env) in advance, and causes viral inactivation [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 496-15-1. Pack Sizes: 10 mM * 1 mL; 25 g; 100 g. Product ID: HY-Y0788. | |
| Indolmycin | Indolmycin (TAK-083), an antibiotic, is a competitive inhibitor of prokaryotic tryptophanyl-tRNA synthetase (TrpS). Indolmycin (TAK-083) possesses both anti-viral and anti-bacterial activity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TAK-083; PA-155A. CAS No. 21200-24-8. Pack Sizes: 1 mg. Product ID: HY-117319. | |
| Indomethacin | Indomethacin (Indometacin) is a potent, orally active COX1/2 inhibitor with IC 50 values of 18 nM and 26 nM for COX-1 and COX-2, respectively. Indomethacin has anticancer activity and anti-infective activity. Indomethacin can be used for cancer, inflammation and viral infection research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Indometacin. CAS No. 53-86-1. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-14397. | |
| Indomethacin sodium hydrate | Indomethacin (Indometacin) sodium hydrateis a potent, orally active COX1/2 inhibitor with IC 50 values of 18 nM and 26 nM for COX-1 and COX-2, respectively. Indomethacin sodium hydrateis has anticancer activity and anti-infective activity. Indomethacin sodium hydrateis can be used for cancer, inflammation and viral infection research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Indometacin sodium hydrate. CAS No. 74252-25-8. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-14397A. | |
| Indoprofen | Indoprofen ((±)-Indoprofe) is a nonsteroidal anti-inflammatory drug used in the study of spinal muscular atrophy. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (±)-Indoprofe. CAS No. 31842-01-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B1104. | |
| Indoramin | Indoramin is an orally active antihypertensive agent. Indoramin is also selective for the α 1A -adrenoceptor [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Indoramine; Wy 21901. CAS No. 26844-12-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12760. | |
| (±)-Indoxacarb | Indoxacarb ((±)-Indoxacarb; DPX-JW062) is a broad-spectrum oxadiazine insecticide with high insecticidal activity and low mammalian toxicity. Indoxacarb blocks insect sodium channels ( Sodium Channel ) in nerve preparations and isolated neurons [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (RS)-Indoxacarb; DPX-JW062. CAS No. 144171-61-9. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-B0834. | |
| Indoximod | Indoximod (1-Methyl-D-tryptophan) is an orally active indoleamine 2,3-dioxygenase ( IDO ) pathway inhibitor. Indoximod acts as a Trp mimetic in regulating mTOR. Indoximod is an immunometabolic adjuvant used for the research of cancer [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 1-Methyl-D-tryptophan; NLG-8189. CAS No. 110117-83-4. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-16724. | |
| Indoxyl sulfate-d4 potassium | Potassium 1H-indol-3-yl sulfate-d 4 (potassium) is the deuterium labeled Potassium 1H-indol-3-yl sulfate. Potassium 1H-indol-3-yl sulfate is an endogenous metabolite. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 1346601-03-3. Pack Sizes: 1 mg. Product ID: HY-W011910S. | |
| Indusatumab | Indusatumab (5F9 Monoclonal antibody) is an anti-human GUCY2C (Guanylate cyclase 2C) monoclonal antibody[1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: 5F9 Monoclonal antibody. CAS No. 1497400-26-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99232. | |
| INDY | INDY is a potent and ATP-competitive Dyrk1A and Dyrk1B inhibitor with IC 50 s of 0.24 μM and 0.23 μM, respectively. INDY binds in the ATP pocket of the enzyme and has a K i value of 0.18 μM for Dyrk1A. INDY sharply reduces the self-renewal capacity of normal and tumorigenic cells in primary Glioblastoma (GBM) cell lines and neural progenitor cells [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1169755-45-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108476. | |
| Inebilizumab | Inebilizumab is an anti- CD19 monoclonal antibody (mAb) with enhanced antibody-dependent cell-mediated cytotoxicity against B cells. Inebilizumab can be used for multiple sclerosis and neuromyelitis optica research [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1299440-37-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99113. | |
| Inebilizumab (FUT8-KO) | Inebilizumab (FUT8-KO) is an anti-CD19 monoclonal antibody expressed by CHO cells with the fucosyltransferase 8 gene (FUT8) knocked out. Fucose deficiency enhances the antibody-dependent cellular cytotoxicity (ADCC) effect of the antibody.Inebilizumab (FUT8-KO) exhibits enhanced ADCC against B cells and can be used for research on multiple sclerosis and neuromyelitis optica[1][2]. Uses: Scientific research. Group: Inhibitory antibodies. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P99113A. | |
| INF7 | INF7 is a derivative of the N-terminal domain of the HA2 protein that can be used to enhance the endosomal escape of polyplexes or liposome-encapsulated proteins[1]. Uses: Scientific research. Group: Peptides. CAS No. 185462-59-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P10152. | |
| Infigratinib | Infigratinib (BGJ-398; NVP-BGJ398) is a potent inhibitor of the FGFR family with IC 50 s of 0.9 nM, 1.4 nM, 1 nM, and 60 nM for FGFR1 , FGFR2 , FGFR3 , and FGFR4 , respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BGJ-398; NVP-BGJ398. CAS No. 872511-34-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-13311. | |
| Infigratinib phosphate | Infigratinib phosphate (BGJ-398 phosphate; NVP-BGJ398 phosphate) is a potent inhibitor of the FGFR family with IC 50 of 0.9 nM, 1.4 nM, 1 nM, and 60 nM for FGFR1 , FGFR2 , FGFR3 , and FGFR4 , respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BGJ-398 phosphate; NVP-BGJ398 phosphate. CAS No. 1310746-10-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-13311A. | |
| Infliximab | Infliximab (Avakine) is a chimeric monoclonal IgG1 antibody that specifically binds to TNF-&alpha. Infliximab prevents the interaction of TNF-α with TNF-α receptor (TNFR1 and TNFR2). Infliximab has the potential for autoimmune, chronic inflammatory diseases and diabetic neuropathy research [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Avakine; CT-P13. CAS No. 170277-31-3. Pack Sizes: 1 mg; 5 mg; 25 mg. Product ID: HY-P9970. | |
| Influenza A virus-IN-1 | Influenza A virus-IN-1 is a dihydropyrrolidones derivative and is a potent inhibitor against wide subtypes of influenza A virus (IAV) with IC 50 values from 3.11 μM to 7.13 μM. Influenza A virus-IN-1 efficiently inhibits replication of IAV , up-regulates the expression of key antiviral cytokines IFN-β and antiviral protein MxA [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2250313-14-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-131179. | |
| Influenza hemagglutinin (HA) epitope | Influenza hemagglutinin (HA) epitope is a polypeptide. Influenza hemagglutinin (HA) epitope is conjugated to keyhole limpet hemocyanin to generate anti-HA polyclonal antibodies following immunization of rabbits [1]. Uses: Scientific research. Group: Peptides. CAS No. 92000-72-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P5271. | |
| Ingenol | Ingenol is a PKC activator, with a K i of 30 μM, with antitumor activity. Uses: Scientific research. Group: Natural products. Alternative Names: (-)-Ingenol. CAS No. 30220-46-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-N0865. | |
| Ingenol Mebutate | Ingenol Mebutate is an active ingredient in Euphorbia peplus , acts as a potent PKC modulator, with K i s of 0.3, 0.105, 0.162, 0.376, and 0.171 nM for PKC-α, PKC-β, PKC-γ, PKC-δ, and PKC-ε, respectively, and has antiinflammatory and antitumor activity. Uses: Scientific research. Group: Natural products. Alternative Names: Ingenol 3-angelate; PEP005. CAS No. 75567-37-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-B0719. | |
| Iniparib | Iniparib (BSI-201) is an irreversible inhibitor of PARP1 , used in the research of triple negative breast cancer. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BSI-201; NSC-746045; IND-71677. CAS No. 160003-66-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-12015. | |
| Inobrodib | Inobrodib (CCS1477) is an orally active, potent, and selective inhibitor of the p300/CBP bromodomain. Inobrodib binds to p300 and CBP with K d values of 1.3 and 1.7 nM, respectively, and with 170/130-fold selectivity compared with BRD4 with a K d of 222 nM. CCS1477 inhibits cell proliferation in prostate cancer cell lines and decreases androgen receptor (AR)- and C-MYC-regulated gene expression [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CCS1477. CAS No. 2222941-37-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-111784. | |
| Inolimomab | Inolimomab is an anti-interleukin-2 receptor ( IL-2R ) α chain monoclonal antibody. Inolimomab improves the survival rate in the early research of treating acute graft-versus-host disease (aGVHD) [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 152981-31-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99664. | |
| Inophyllum E | Inophyllum E is a natural product [1]. Uses: Scientific research. Group: Natural products. CAS No. 17312-31-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N13645. | |
| Inorganic pyrophosphatase, Saccharomyces cerevisiae | Inorganic pyrophosphatase, Saccharomyces cerevisiae (PPase) converts pyrophosphate (PPi) to phosphate. Inorganic pyrophosphatase is an essential component of in vitro transcription reactions for RNA preparation, is often used in biochemical studies. Inorganic pyrophosphatase is critical for driving cellular processes such as nucleic acid and protein synthesis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PPase. CAS No. 9024-82-2. Pack Sizes: 100 U. Product ID: HY-P2992. | |
| Inosine | Inosine is an endogenous purine nucleoside produced by catabolism of adenosine. Inosine has anti-inflammatory, antinociceptive, immunomodulatory and neuroprotective effects. Inosine is an agonist for adenosine A 1 ( A 1 R ) and A 2A ( A 2A R ) receptors [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 58-63-9. Pack Sizes: 10 mM * 1 mL; 500 mg; 25 g. Product ID: HY-N0092. | |
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