MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Inosine 5-diphosphate sodium | Inosine 5-diphosphate sodium is a purine ribonucleoside 5-diphosphate with inosine as the nucleobase, which can participate in intracellular energy metabolism and signal transduction processes [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 81012-88-6. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-W749117. |  |
| Inosine-5-monophosphate disodium salt octahydrate | Inosine-5'-monophosphate disodium salt octahydrate is a purine nucleotide that can be used as an umami tastant as well as a precursor of GMP and AMP [1]. Uses: Scientific research. Group: Natural products. CAS No. 20813-76-7. Pack Sizes: 5 g. Product ID: HY-W010759. | |
| Inosine-5'-triphosphate trisodium salt | Inosine-5'-triphosphate trisodium salt is a nucleoside triphosphate and functions as an substrate for ATPases and GTPases [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 35908-31-7. Pack Sizes: 50 mg; 100 mg. Product ID: HY-W013706. | |
| Inosine pranobex | Inosine pranobex is an orally active immunomodulator. Inosine pranobex has broad-spectrum antiviral activity. Inosine pranobex inhibits human immunodeficiency virus (HIV), herpes simplex virus (HSV), vaccinia virus (VACV), human tumor virus (HPV), Cytomegalovirus, influenza virus (INFV), parainfluenza virus (PIV), and Epstein-Barr virus [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Imunovir; Delimmun; Groprinosin. CAS No. 36703-88-5. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-107801. | |
| Inosinic acid | Inosinic acid is an endogenous metabolite. Inosinic acid is used as umami tastant, or as the dietary supplement to improve the yield and meat quality of pigs [1]. Uses: Scientific research. Group: Natural products. Alternative Names: 5'-IMP; IMP; Inosine 5'-(dihydrogen phosphate). CAS No. 131-99-7. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-108213. | |
| Inositol nicotinate | Inositol nicotinate (Hexanicit) has vasodilating effects and can be used in research on peripheral arterial disease, showing efficacy when taken orally. Inositol nicotinate does not significantly improve triglyceride levels in mice induced by biphenyl esters [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Inositol niacinate; Hexanicit. CAS No. 6556-11-2. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-122365. | |
| Inotersen sodium | Inotersen (ISIS-420915) sodium is a 2?-O-methoxyethyl-modified antisense oligonucleotide. Inotersen sodium inhibits the production of transthyretin (TTR) protein by targeting the TTR RNA transcript and reduces the levels of the TTR transcript. Inotersen sodium can be used for the research of hereditary TTR amyloidosis polyneuropathy[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ISIS-420915 sodium. CAS No. 1432726-13-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132608. | |
| Inotodiol | Inotodiol activates p53 signaling pathway, inhibits MMP-2/9, and exhibits antitumor activity in cancer cell HeLa. Inotodiol inhibits the generation of ROS and exhibits antioxidant and neuroprotective effects. Inotodiol inhibits the activation of MAPK and NF-?B signaling pathway, and exhibits anti-inflammatory activity. Inotodiol inhibits TLR-4 mediated TNF-? production (IC50s in BMMC and BMDM is 0.7 ?M and 3.0 ?M), inhibits the degranulation in mast cell, exhibits anti-allergic activity. Inotodiol is orally active[1][2][3][4][5]. Uses: Scientific research. Group: Natural products. CAS No. 35963-37-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-120149. | |
| Inotuzumab | Inotuzumab (Humanized Anti-CD22 Recombinant Antibody) is a humanized IgG4, κ antibody that targets human CD22. Inotuzumab can be linked to a toxic agent ozogamicin as an antibody-drug conjugate (ADC). Inotuzumab can be used for the research of acute lymphoblastic leukemia and non-Hodgkin lymphoma [1] [2] [3] [4]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Humanized Anti-CD22 Recombinant Antibody. CAS No. 1660159-36-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99264. | |
| INS018 055 | INS018 055 (compound 112) is a TNIK and MAP4K4 inhibitor with IC 50 values of 12-120, 12-120 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TNIK&MAP4K4-IN-2. CAS No. 2828567-39-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-160623. | |
| INSA | INSA is a a pH-sensitive fluorescent probe. INSA can simultaneously light up mitochondria (red emission) and lysosomes (green emission) for their internal pH differences [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 2962939-33-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-157036. | |
| Insulin aspart | Insulin aspart (B28Asp) is a fast-acting analog of human insulin. Insulin aspart provides more rapid absorption than regular human insulin after subcutaneous administration. Insulin aspart can be used for researching diabetes [1]. Uses: Scientific research. Group: Peptides. Alternative Names: B28Asp; B28-Asp-insulin; INA-X 14; Insulin X 14. CAS No. 116094-23-6. Pack Sizes: 100 U; 300 U. Product ID: HY-108767. | |
| Insulin(cattle) | Insulin cattle is a two-chain polypeptide hormone produced in vivo in the pancreatic β cells. Insulin cattle has often been used as growth supplement in culturing cells. Uses: Scientific research. Group: Peptides. CAS No. 11070-73-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P1156. | |
| Insulin degludec | Insulin degludec is an ultra-long-acting form of insulin used for the research of hyperglycemia caused by type 1 and type 2 dabetes. Insulin degludec shows binding efficiency with an IC 50 value of 19.59 nM for insulin receptor. Insulin degludec can be used for the research of type 1 and type 2 diabetes [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 844439-96-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108743. | |
| Insulin Detemir | Insulin Detemir is an artificial insulin, shows effect on controlling blood sugar levels. Insulin Detemir stimulates GLP-1 secretion as a consequence of enhanced Gcg expression by a mechanism involving activation of Akt - and/or extracellular signal-regulated kinase ( ERK )-dependent-cat and CREB signaling pathways. Insulin Detemir can be used for type 2 diabetes research [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 169148-63-4. Pack Sizes: 100 U; 300 U. Product ID: HY-109556. | |
| Insulin efsitora alfa | Insulin efsitora alfa (LY-3209590) is a selective agonist of insulin receptor (IR). Insulin efsitora alfa is a fusion protein composed of human IR agonists fused with the crystallizable (Fc) domain of human immunoglobulin G2 (IgG2) fragment, with a molecular weight of 64.1 kDa. Insulin efsitora alfa is well tolerated and has potential applications in diabetes [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: LY-3209590. CAS No. 2131038-11-2. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-P99665. | |
| Insulin glargine | Insulin glargine is a long-acting insulin analog. Insulin glargine has the effect of lowering blood sugar and can be used in the research of diabetes. In addition, high doses of Insulin glargine can promote the proliferation of bladder cancer cells [1] [2] [3] [4]. Uses: Scientific research. Group: Peptides. CAS No. 160337-95-1. Pack Sizes: 100 U; 300 U. Product ID: HY-108719. | |
| Insulin glulisine | Insulin glulisine (HMR 1964) is a rapid-acting insulin analogue, it mimics the pharmacokinetic and pharmacodynamic profiles of physiological human insulin. Insulin glulisine can be used for the research of diabetes [1]. Uses: Scientific research. Group: Peptides. Alternative Names: HMR 1964. CAS No. 207748-29-6. Pack Sizes: 100 U. Product ID: HY-109555. | |
| Insulin (human) | Insulin (human) is a polypeptide hormone that regulates the level of glucose. Insulin (human) can be used for the diabetes mellitus [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 11061-68-0. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P0035. | |
| Insulin lispro | Insulin lispro is a recombinant human insulin analogue and is one of three rapid-acting insulin analogues available. Insulin lispro can be used for the research of hyperglycaemia in diabetes mellitus [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 133107-64-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-109530. | |
| Insulin solution (human) | Insulin solution (human) is a polypeptide hormone that regulates the level of glucose. Insulin solution (human) can be used for the diabetes mellitus [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 11061-68-0. Pack Sizes: 10 mg. Product ID: HY-P0035A. | |
| Insulin (swine) | Insulin (swine) is a porcine-derived insulin used in diabetes research [1]. Uses: Scientific research. Group: Peptides. CAS No. 12584-58-6. Pack Sizes: 10 mg; 50 mg; 100 mg. Product ID: HY-P3479. | |
| Insulin-Transferrin-Selenium, 100X | Insulin-Transferrin-Selenium, 100X (ITS-G) is a mixture of Insulin, transferrin, and sodium selenite that is a general supplement designed for use in classic media such as DMEM, RPMI-1640, and nutrient media such as Ham's F-12, DMEM/F-12. Insulin-Transferrin-Selenium is added to basal medium to reduce the amount of fetal calf serum required to culture cells[1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: ITS-G. Pack Sizes: 10 mL. Product ID: HY-150287. | |
| INT | INT (Iodonitrotetrazolium chloride) is a biochemical reagent mainly used in the iodonitrotetrazolium chloride (INT) colorimetric method to assess the metabolic activity of cells and the activity of enzymes [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Iodonitrotetrazolium chloride; p-Iodonitrotetrazolium Violet. CAS No. 146-68-9. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-15920. | |
| INT-777 | INT-777 is a potent TGR5 agonist with an EC50 of 0.82 ?M[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: S-EMCA. CAS No. 1199796-29-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15677. | |
| Integrin Binding Peptide | Integrin Binding Peptide is derived by fibronectin. Integrin Binding Peptide can be used for PEG hydrogel preparation [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 278792-07-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P2532. | |
| Intepirdine | Intepirdine (SB742457) is a highly selective 5-HT6 receptor antagonist with pKi of 9.63; exhibits >100-fold selectivity over other receptors. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SB-742457; GSK-742457; RVT-101. CAS No. 607742-69-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14339. | |
| Interiorin | Interiorin can be isolated from Kadsura heteroclita and has moderate anti-HIV activity with an EC50 value of 1.6 lg/mL [1]. Uses: Scientific research. Group: Natural products. CAS No. 119139-55-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N11949. | |
| Intetumumab | Intetumumab (CNTO 95) is a potent anti- EGFR monoclonal antibody that is glycoengineered for enhanced antibody-dependent cellular cytotoxicity (ADCC). Intetumumab can be used in research of cancer [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: CNTO 95; Anti-Human CD51 Recombinant Antibody. CAS No. 725735-28-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99296. | |
| Intralipid 20% | Intralipid 20% is a safe fat emulsion that can be used as a nutritional supplement. Intralipid 20% effectively inhibits the opening of the mitochondrial permeability transition pore, effectively protecting the heart from ischaemia-reperfusion injury and has some potential to modulate the innate immune response [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 68890-65-3. Pack Sizes: 100 mg. Product ID: HY-131370B. | |
| Inulin | Inulin is an orally active prebiotic targeting the intestinal microbiota, selectively promoting the proliferation and activity of beneficial bacteria such as bifidobacteria and lactic acid bacteria, and playing a role in regulating the intestinal microecology. The functions of Inulin include: ? Fermentation by probiotics in the colon to produce short-chain fatty acids (such as butyrate and propionate), lowering the intestinal pH and inhibiting the overgrowth of harmful bacteria; ? Enhancing the intestinal barrier function and reducing endotoxin translocation; ? Directly scavenging free radicals (such as superoxide free radicals, hydroxyl free radicals) and activating antioxidant enzymes (SOD, CAT) to reduce oxidative stress. Inulin can also be used in the study of intestinal diseases (constipation, IBD), metabolic syndrome (diabetes, obesity) and liver damage by regulating glucose and lipid metabolism (such as reducing triglycerides, improving insulin sensitivity) and immune response (enhancing NK cell activity, inhibiting inflammatory factors) [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 9005-80-5. Pack Sizes: 100 mg. Product ID: HY-N7075. | |
| Inulinase | Inulinase is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Signaling pathways. CAS No. 9025-67-6. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-P3261. | |
| Inupadenant | Inupadenant is an orally active, highly selective A2A receptor antagonist. Inupadenant can not cross BBB. Inupadenant can enhance the humoral immune response and has anti-tumor activity[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EOS-850. CAS No. 2246607-08-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137442. | |
| Invertase, baker's yeast (S. cerevisiae) | Invertase, baker's yeast (S. cerevisiae) is a major enzyme present in plants and microorganisms, is often used in biochemical studies. Invertase catalyzes the hydrolysis of the disaccharide sucrose into glucose and fructose [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: β-D-Fructofuranosidase. CAS No. 9001-57-4. Pack Sizes: 250 mg; 500 mg; 1 g. Product ID: HY-P2979. | |
| INX-315 | INX-315 is an orally active and selective CDK2 inhibitor that induces cell cycle arrest in the G1 phase. INX-315 reduces CDK2 substrate phosphorylation and inhibits tumor growth in a dose-dependent manner in xenograft mouse models. INX-315 may be used in cancer research[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2745060-92-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-162001. | |
| Inz-5 | Inz-5 is a fungal-selective mitochondrial cytochrome bc1 inhibitor. Inz-5 impairs fungal virulence and prevents the evolution of agent resistance[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1585214-21-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-121721. | |
| Iobenguane sulfate | Iobenguane sulfate (MIBG sulfate) is an analogue of the neurotransmitter norepinephrine with antitumor activity. Radioiodinated Iobenguane sulfate is clinically used as a tumor-targeted radiopharmaceutical in the diagnosis and treatment of adrenergic tumors. Iobenguane sulfate is a high-affinity substrate for cholera toxin that interferes with cellular mono(ADP-ribosylation) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MIBG sulfate. CAS No. 87862-25-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129040A. | |
| Iodipamide | Iodipamide is a tri-iodinated benzoate derivative and ionic dimeric contrast agent used in diagnostic imaging. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Adipiodone. CAS No. 606-17-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-B1292. | |
| Iodixanol | Iodixanol is an iodine-containing non-ionic radiocontrast agent [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 92339-11-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1426. | |
| Iodobenzene | Iodobenzene (1-Iodobenzene) is a biological material or organic compound that can be used in life science research [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: 1-Iodobenzene. CAS No. 591-50-4. Pack Sizes: 10 mM * 1 mL; 25 g; 100 g. Product ID: HY-Y0747. | |
| Iohexol | Iohexol is a non-ionic, water-soluble contrast agent used as a reference marker for the determination of glomerular filtration rate (GFR) at the level of renal function. Iohexol can be used for contrast in myelography, computerized tomography (cisternography, ventriculography) and MicroCT imaging [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 66108-95-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0594. | |
| I-OMe-Tyrphostin AG 538 | I-OMe-Tyrphostin AG 538 (I-OMe-AG 538) is a specific inhibitor of IGF-1R (insulin-like growth factor-1 receptor tyrosine kinase). I-OMe-Tyrphostin AG 538 inhibits IGF-1R-mediated signaling and is preferentially cytotoxic to nutrient-deprived PANC1 cells. I-OMe-Tyrphostin AG 538 is an ATP-competitive inhibitor of phosphatidylinositol-5-phosphate 4-kinase α (PI5P4Kα) , with an IC 50 of 1 μM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: I-OMe-AG 538. CAS No. 1094048-77-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135680. | |
| IONIS-FB-LRx sodium | IONIS-FB-LRx sodium is a specific antisense oligonucleotide (ASO) targeting complement factor B (CFB). IONIS-FB-LRx sodium effectively reduces circulating levels of CFB, and can be used for geographic atrophy (GA) research[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RG6299 sodium. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-148370A. | |
| IONIS-MAPTRx sodium | IONIS-MAPTRx sodium is the first Tau-lowering antisense oligonucleotide (ASO). IONIS-MAPTRx sodium has the potential for the research of Alzheimer Disease[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BIIB080 sodium; ISIS 814907 sodium. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-132582C. | |
| Ionizable lipid-1 | Ionizable lipid-1 (compound II-10) is an ionizable lipid ( pKa =6.16) that can be used to prepare lipid nanoparticles (LNP) with bilayer structure [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 2055939-68-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156630. | |
| Ionomycin | Ionomycin (SQ23377) is a potent, selective calcium ionophore and an antibiotic produced by Streptomyces conglobatus. Ionomycin (SQ23377) is highly specific for divalent cations (Ca>Mg>Sr=Ba). Ionomycin (SQ23377) promotes apoptosis. Ionomycin also induces the activation of protein kinase C (PKC) [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: SQ23377. CAS No. 56092-81-0. Pack Sizes: 1 mg (14.1 mM * 100 μL in Ethanol); 5 mg (14.1 mM * 500 μL in Ethanol); 10 mg (14.1 mM * 1 mL in Ethanol). Product ID: HY-13434. | |
| Ionomycin calcium | Ionomycin calcium (SQ23377 calcium) is a potent, selective calcium ionophore and an antibiotic produced by Streptomyces conglobatus. Ionomycin calcium (SQ23377 calcium) is highly specific for divalent cations (Ca>Mg>Sr=Ba). Ionomycin (SQ23377) promotes apoptosis. Ionomycin calcium (SQ23377 calcium) also induces the activation of protein kinase C (PKC) [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: SQ23377 calcium. CAS No. 56092-82-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-13434A. | |
| Iopamidol | Iopamidol is a nonionic, X-Ray iodinated contrast agent (CA) for a wide variety of diagnostic applications. Iopamidol contains amide and hydroxyl functionalities that can be exploited for the generation of the chemical exchange saturation transfer (CEST) contrast [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: B-15000; SQ-13396. CAS No. 60166-93-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0684. | |
| Iopanoic acid | Iopanoic acid is an inhibitor of 5'-Deiodinase and also an iodinated contrast medium. Uses: Scientific research. Group: Signaling pathways. CAS No. 96-83-3. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B1664. | |
| Iopentol | Iopentol is a non-ionic, intravascular contrast media [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 89797-00-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-142121. | |
| Iopromide | Iopromide is a non-ionic, monomeric, iodine-based contrast medium for intravascular administration. Uses: Scientific research. Group: Signaling pathways. CAS No. 73334-07-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1362. | |
| Ι-Carrageenan | Ι-Carrageenan (Viscarin SD 309) is a biochemical reagent. Ι-Carrageenan can be isolated from Eucheuma serra or red algae H. musciformis and S. filiformis. Ι-Carrageenan has potential application in protein emulsion flocculation and stability [1] [2] [3] [4]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Viscarin SD 309. CAS No. 9062-7-1. Pack Sizes: 5 g. Product ID: HY-W145523. | |
| Iotalamic acid | Lotalamic acid (Iothalamic acid) is a contrast agent. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Iothalamic acid. CAS No. 2276-90-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-B1053. | |
| Ioversol | Ioversol (MP-328) is a nonionic iodinated contrast medium (CM) that is used during a CT scan or x-ray in animal experiment. Ioversol does not damage the blood-brain barrier (BBB) in animal [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MP-328. CAS No. 87771-40-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B1410. | |
| IOX1 | IOX1, 5-Carboxy-8-hydroxyquinoline, is a potent broad?spectrum inhibitor of 2OG oxygenases, including the JmjC demethylases. IOX1 inhibits KDM4C, KDM4E, KDM2A, KDM3A and KDM6B with IC50 values of 0.6 ?M, 2.3 ?M, 1.8 ?M, 0.1 ?M and 1.4 ?M, respectively[1][2]. IOX1 also inhibits ALKBH5[3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 5852-78-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-12304. | |
| IOX2 | IOX2 is a specific prolyl hydroxylase-2 ( PHD2 ) inhibitor with IC 50 of 22 nM. IOX2 regulates platelet function and arterial thrombosis by upregulating HIF-1α expression and inhibiting ROS production. IOX2 can be used in the study of thrombotic diseases [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 931398-72-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15468. | |
| IOX4 | IOX4 is a selective HIF prolyl-hydroxylase 2 (PHD2) inhibitor with an IC50 value of 1.6 nM, induces HIF? in cells and in wildtype mice with marked induction in the brain tissue. IOX4 competes with and displaces 2-oxoglutarate (2OG) at the active site of PHD2[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1154097-71-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-120110. | |
| Ioxilan | Ioxilan is a low-osmolar, nonionic and tri-iodinated diagnostic contrast agent. Ioxilan is also an X-ray contrast agent for excretory urography and contrast enhanced computed tomographic (CECT) imaging of the head and body. Intravascular injection results in opacification of vessels in the path of flow of the contrast medium, permitting radiographic visualization of the internal structures of the human body until significant hemodilution occurs [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 107793-72-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-109513. | |
| IP6K2-IN-2 | IP6K2-IN-2 (Compound 6) is an IP6K2 inhibitor, with IC 50 values of 0.58 μM ( IP6K2 ), 0.86 μM ( IP6K1 ) and 3.08 μM ( IP6K3 ). IP6K2-IN-2 can be used in research of obesity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2967648-66-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-122706A. | |
| IP7e | IP7e is a potent, brain-penetrant and orally active Nurr1 activator with an EC50 value of 3.9 nM[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 500164-74-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110274. | |
| IPA-3 | IPA-3 is a selective non-ATP competitive PAK1 inhibitor with IC 50 of 2.5 μM, and shows no inhibition to group II PAKs (PAKs 4-6). Uses: Scientific research. Group: Signaling pathways. CAS No. 42521-82-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15663. | |
| iPAF1C | iPAF1C is a potent inhibitor of polymerase-associated factor 1 complex (PAF1C). iPAF1C has anti-HIV activity[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 950403-60-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-160267. | |
| IPAG | IPAG is a potent sigma-1 receptor antagonist with a pK i of 4.3 [1]. IPAG induces apoptosis [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 193527-91-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100985. | |
| Ipatasertib | Ipatasertib (GDC-0068) is an orally active, highly selective and ATP-competitive pan- Akt inhibitor with IC 50 values of 5, 18, 8 nM for Akt1/2/3 , respectively. Ipatasertib synchronously activates FoxO3a and NF-κB through inhibition of Akt leading to p53-independent activation of PUMA. Ipatasertib also induces apoptosis in cancer cells and inhibits tumor growth in xenograft mouse models [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GDC-0068; RG7440. CAS No. 1001264-89-6. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-15186. | |
| Ipatasertib dihydrochloride | Ipatasertib dihydrochloride (GDC-0068 dihydrochloride) is a highly selective and ATP-competitive pan-Akt inhibitor with IC 50 s of 5, 18 and 8 nM for Akt1 , Akt2 and Akt3 , respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GDC-0068 dihydrochloride; RG-7440 dihydrochloride. CAS No. 1396257-94-5. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-15186A. | |
| Iperoxo | Iperoxo is a potent superagonist of muscarinic acetylcholine receptor (mAChR) that activates M1, M2 and M3 receptors with pEC50 of 9.87, 10.1 and 9.78. Iperoxo can be used for direct probing activation-related conformational transitions of muscarinic receptors when labeled with tritium[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 247079-84-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-122743. | |
| Ipflufenoquin | Ipflufenoquin is an insecticide with the potential to control primary infection with apple scab. Ipflufenoquin should be applied between half an inch of green and fruit set [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1314008-27-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-134338. | |
| IPI-9119 | IPI-9119 is an orally active, selective and irreversible FASN inhibitor with an IC50 of 0.3 nM in vitro biochemical assay. IPI-9119 inhibits tumor growth of castration-resistant prostate cancer (CRPC) xenografts mouse models[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1346564-56-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124628. | |
| Ipidacrine | Ipidacrine is orally active and brain-penetrant AChE and BuChE inhibitors with IC 50 values of 1 μM and 1.9 μM, respectively, which is also a partial agonist of M2-cholinergic receptors and a reversible cholinesterase inhibitor. Ipidacrine has a stimulating effect on neuromuscular transmission and excitation along the nerve fibres with a moderately anti-pain effect. Ipidacrine is an aminopyridines and is structurally similar to Tacrine (HY-111338). Ipidacrine is effective in various amnesia models, improves erectile function and inhibits K + and Na + -channels in the neuronal membrane in diabetic rats. Ipidacrine is promising for research of Alzheimers disease, ischaemic stroke, idiopathic neuropathy of the facial nerve, diabetes mellitus-induced erectile dysfunction and other deficits in central or peripheral cholinergic deseases [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NIK-247 free base. CAS No. 62732-44-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-W027553. | |
| Ipilimumab | Ipilimumab is a fully human monoclonal antibody IgG1κ that blocks the inhibitory receptor cytotoxic T lymphocyte antigen 4 ( CTLA-4 ) on T cells. Ipilimumab can be used in unresectable or metastatic melanoma (MM) studies [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MDX-010; BMS-734016. CAS No. 477202-00-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P9901. | |
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