MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Isoprocarb | Isoprocarb is carbamate insecticide that widely used to control rice paddy lice and leafhopper. Isoprocarb is also an AChE inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2631-40-5. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B0830. |  |
| Isopropamide iodide | Isopropamide iodide is a long-acting quaternary anticholinergic agent. Isopropamide iodide is used in peptic ulcer and other gastrointestinal disorders marked by hyperacidity and hypermotility [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 71-81-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B1667. | |
| Isopropyl 4-hydroxybenzoate | Isopropyl 4-hydroxybenzoate (Isopropylparaben) is an antimicrobial and antioxidant agent [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Isopropylparaben. CAS No. 4191-73-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W016491. | |
| Isopropyl palmitate | Isopropyl palmitate is an fatty acid ester. Isopropyl palmitate can be used for design and characterization of bioactive bilayer films. The bilayer membrane not only has the ability to scavenge free radicals and inhibit lipid peroxidation, but also can inhibit the growth of known foodborne pathogens. Isopropyl palmitate can be used as an excipient, such as lubricant, oily carrier, solvent, controlled-release transdermal film. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Propan-2-yl hexadecanoate. CAS No. 142-91-6. Pack Sizes: 10 mM * 1 mL; 25 g; 100 g. Product ID: HY-W011426. | |
| Isopropyl unoprostone | Isopropyl unoprostone (Unoprostone isopropyl ester), an analogue of a prostaglandin metabolite, is a potent large conductance Ca 2+ -activated K + (BK) channels activator. Isopropyl unoprostone has antiglaucoma effects, lowering intraocular pressure (IOP) by increasing aqueous humour outflow. Isopropyl unoprostone can improve retinal sensitivity and the protection of central retinal sensitivity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Unoprostone isopropyl ester; UF-021. CAS No. 120373-24-2. Pack Sizes: 1 mg (23.55 mM * 100 μL in Methyl acetate). Product ID: HY-109545. | |
| (-)-Isoproterenol hydrochloride | (-)-Isoproterenol (Levisoprenaline; Proternol L) hydrochloride is a β-adrenoceptor agonist. (-)-Isoproterenol induces ventricular remodeling [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Levisoprenaline hydrochloride; Proternol L hydrochloride. CAS No. 5984-95-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-B1670A. | |
| Isoprothiolane | Isoprothiolane is a systemic fungicide. Isoprothiolane is a rice blast controlling agent against the fungal disease of rice planty Pyvioutavia oryzae Cav [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 50512-35-1. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-B1858. | |
| Isoproturon | Isoproturon belongs to the phenylurea herbicide family and is a systemic and selective herbicide. Isoproturon is widely applied for killing weeds in farmland, which can be used in the control of annual grasses and broad-leaved weeds in spring and winter wheat, winter rye and spring and winter barley [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 34123-59-6. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-B1859. | |
| (-)-Isopulegol | (-)-Isopulegol is prepared directly from the treatment of essential oil of citronella under solid supported acid catalysis and solvent-free microwave assisted ene-cyclisation. (-)-Isopulegol shows high activity in reacting with carbonyl compounds. (-)-Isopulegol can be used for antiviral activity research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 89-79-2. Pack Sizes: 10 mM * 1 mL; 10 g; 25 g; 50 g; 100 g. Product ID: HY-121206. | |
| Isoquercitrin | Isoquercetin (Quercetin 3-glucoside) is a naturally occurring polyphenol that has antioxidant, anti-proliferative, and anti-inflammatory properties. Isoquercetin alleviates ethanol-induced hepatotoxicity, oxidative stress, and inflammatory responses via the Nrf2/ARE antioxidant signaling pathway [1]. Isoquercetin regulates the expression of nitric oxide synthase 2 ( NO2 ) via modulating the nuclear factor-κB ( NF-κB ) transcription regulation system. Isoquercetin has high bioavailability and low toxicity, is a promising candidate agent to prevent birth defects in diabetic pregnancies [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Isoquercetin; Quercetin 3-glucoside. CAS No. 482-35-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N1445. | |
| Isoquinoline | Isoquinoline is an analog of pyridine. Isoquinoline-based alkaloids, such as p-tolyl bisisoquinoline, phthaloyl isoquinoline, and naphthyl isoquinoline, exhibit anticancer activity. Berberine, an isoquinoline alkaloid, exerts anti-inflammatory effects in diabetic mice by downregulating the gene expression ratios of pro-/anti-inflammatory and Th1/Th2 cytokines. Additionally, some isoquinoline-based compounds also possess antidepressant, antibacterial, antimalarial, and anti- HIV activities [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. CAS No. 119-65-3. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-W012732. | |
| Isorhamnetin | Isorhamnetin is a flavonoid compound extracted from the Chinese herb Hippophae rhamnoides L. Isorhamnetin suppresses skin cancer through direct inhibition of MEK1 and PI3K. Uses: Scientific research. Group: Natural products. Alternative Names: 3'-Methylquercetin. CAS No. 480-19-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N0776. | |
| Isorhapontigenin | Isorhapontigenin, an orally bioavailable dietary polyphenol isolated from the Chinese herb Gnetum cleistostachyum , displays anti-inflammatory effects. Isorhapontigenin induces autophagy and inhibits invasive bladder cancer formation [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 32507-66-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N2593. | |
| Isosakuranetin | Isosakuranetin is a flavanone flavonoid which can be found in the fruit of Citrus bergamia. Isosakuranetin is a TRPM3 blocker[1][2][3]. Uses: Scientific research. Group: Natural products. CAS No. 480-43-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N2131. | |
| Isoscopoletin | Isoscopoletin (6-Hydroxy-7-methoxycoumarin) is an active constituent in Artemisia argyi leaves. Isoscopoletin shows substantial inhibition against cell proliferation, with IC 50 s of 4.0 μM and 1.6 μM for human CCRF-CEM leukaemia cells and multidrug resistant subline CEM/ADR5000, respectively [1]. Isoscopoletin (6-Hydroxy-7-methoxycoumarin) possesses inhibitory activity against HBV replication [2]. Uses: Scientific research. Group: Natural products. Alternative Names: 6-Hydroxy-7-methoxycoumarin. CAS No. 776-86-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N1365. | |
| Isoscutellarein | Isoscutellarein is a flavonoid compound that can be isolated from Wissadula periplocifolia (L.) C. Presl (Malvaceae) [1]. Uses: Scientific research. Group: Natural products. Alternative Names: 8-Hydroxyapigenin. CAS No. 41440-05-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N8363. | |
| Isosilybin | Isosilybin (Isosilybinin) is a flavonoid from Silybum marianum ; inhibits CYP3A4 induction with an IC 50 of 74 μM. Uses: Scientific research. Group: Natural products. Alternative Names: Isosilybinin. CAS No. 72581-71-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0779. | |
| Isosorbide | Isosorbide (D-Isosorbide), an orally active vasodilating agent that can be used for the research of heart failure and angina (chest pain). Isosorbide is also an oral hyperosmotic diuretic [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: D-Isosorbide; Dianhydro-D-glucitol. CAS No. 652-67-5. Pack Sizes: 10 mM * 1 mL; 500 mg; 5 g. Product ID: HY-B1469. | |
| Isosorbide dinitrate | Isosorbide dinitrate (ISDN) is an NO donor that prevents LV remodeling and degradation of cardiac function following myocardial infarction (MI) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ISDN. CAS No. 87-33-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1409. | |
| Isosorbide mononitrate | Isosorbide mononitrate (Isosorbide-5-mononitrate) is an orally active nitric acid compound used for angina pectoris by dilating blood vessels and lowering blood pressure. Isosorbide mononitrate increases the viability and proliferation of HUVECs by decreasing Apoptosis and elevated the expressions of vedf, kdrl, pdgfr in zebrafish embryos. Isosorbide mononitrate is promising for research of heart failure and coronary heart disease [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Isosorbide-5-mononitrate. CAS No. 16051-77-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0642. | |
| Isostearic acid | Isostearic acid is a unique fatty acid. Isostearic acid promotes IL-1 release and Apoptosis. Isostearic acid has potent inflammatory properties. Isostearic acid can be used in pharmaceutical, personal care, and cosmetic applications [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 2724-58-5. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-W127433. | |
| Isosteviol | Isosteviol ((-)-Isosteviol) is a derivative of Stevioside through acid catalyzed hydrolysis of Stevioside. Isosteviol inhibits DNA polymerase and DNA topoisomerase and has antibacterial, anticancer and anti-tuberculosis effects [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: (-)-Isosteviol; iso-Steviol. CAS No. 27975-19-5. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-N0872. | |
| Isosulfan blue | Isosulfan blue is a blue dye for the identification of lymph vessels during lymphangiography. Isosulfan blueis is used during sentinel lymph node biopsies in breast cancer. Isosulfan blue is possible to have an allergic reaction during breast cancer operations [1] [2]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 68238-36-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107967. | |
| Isotetrandrine | Isotetrandrine is a bioactive component in Stephania tetrandra [1]. Uses: Scientific research. Group: Natural products. CAS No. 477-57-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N6045. | |
| Isothiafludine | Isothiafludine is an orally active non-nucleosidic anti- HBV compound. Isothiafludine inhibits hepatitis B virus replication by blocking pregenomic RNA encapsidation [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NZ-4. CAS No. 960527-22-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-111003. | |
| Isotodesnitazene | Isotodesnitazene is a kind of opioids. Isotodesnitazene primarily acts on μ-opioid receptors ( MOR ). Isotodesnitazene has an EC 50 of 34.8 nM for MOR-βarr2 and 142 nM for MOR-mini-Gi. Isotodesnitazene can be used in the study of opioids [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2732926-27-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-164747. | |
| Isotretinoin | Isotretinoin (13-cis-Retinoic acid) is an orally active vitamin A derivative and is often be used for the research of severe acne. Isotretinoin also shows anticancer activity [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: 13-cis-Retinoic acid. CAS No. 4759-48-2. Pack Sizes: 100 mg; 500 mg; 1 g. Product ID: HY-15127. | |
| Isovaleric acid | Isovaleric acid is an oral active short-chain fatty acid that inhibits osteoclast differentiation by stimulating AMPK phosphorylation and promotes colonic smooth muscle relaxation by activating the cAMP/PKA pathway. Isovaleric acid can be used in research on skeletal diseases (such as osteoporosis) and intestinal disorders [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 503-74-2. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-W012980. | |
| Isovalerylcarnitine | Isovalerylcarnitine is a product of the catabolism of L-leucine. Isovalerylcarnitine is also a selective and reversible calpain activator that induces apoptosis [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 31023-24-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-113221. | |
| Isovalerylcarnitine chloride | Isovalerylcarnitine chloride, a product of the catabolism of L-leucine, is a potent activator of the Ca 2+ -dependent proteinase ( calpain ) of human neutrophils [1]. Uses: Scientific research. Group: Natural products. CAS No. 139144-12-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145542. | |
| Isovanillin | Isovanillin is an aldehyde oxidase inhibitor [1]. Antispasmodic activities [2]. Antidiarrheal activities [3]. Uses: Scientific research. Group: Natural products. Alternative Names: 3-Hydroxy-4-methoxybenzaldehyde. CAS No. 621-59-0. Pack Sizes: 10 mM * 1 mL; 5 g; 10 g. Product ID: HY-I0637. | |
| Isovitexin | Isovitexin is a flavonoid isolated from passion flower, Cannabis and, and the palm, possesses anti-inflammatory and anti-oxidant activities; Isovitexin acts like a JNK1/2 inhibitor and inhibits the activation of NF-κB. Uses: Scientific research. Group: Natural products. Alternative Names: Saponaretin; Homovitexin. CAS No. 38953-85-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0773. | |
| Isovitexin 2''-O-arabinoside | Isovitexin 2''-O-arabinoside is a flavonoid in plantlets of Avena sativa L.[1]. Uses: Scientific research. Group: Natural products. CAS No. 53382-71-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N5114. | |
| Isoxadifen-ethyl | Isoxadifen-ethyl is a widely used herbicide safener in rice which can decrease the phytotoxicity caused by fenoxaprop-P-ethyl [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 163520-33-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-130361. | |
| Isoxaflutole | Isoxaflutole (Merlin; RP-201772) is a selective herbicide for pre-emergence control of a wide range of important broadleaf and grass weeds in corn and sugarcane. Isoxaflutole is a precursor and delivery vector of diketonitrile (DKN), which is an inhibitor for 4-hydroxyphenylpyruvate dioxygenase ( HPPD ), leads to a characteristic bleaching of susceptible species [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Merlin; RP-201772. CAS No. 141112-29-0. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116139. | |
| Isoxanthohumol | Isoxanthohumol is a prenylflavonoid from hops and beer. Isoxanthohumol exhibits an antiproliferative activity against several human cancer cell lines. Isoxanthohumol inhibits the development of lung metastatic foci in tumor-challenged animals. Isoxanthohumol shows an antiviral activity towards herpes viruses (HSV1 and HSV2) and bovine viral diarrhea virus (BVDV) [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 521-48-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N2584A. | |
| Isoxanthopterin | Isoxanthopterin is a heterocyclic compound belonging to the pteridine family and its activity is mainly reflected in its optical properties. Isoxanthopterin can form a reflective layer in the eyes of animals, enhancing visual function. The main regulatory mechanism of isoxanthopterin involves its ability to form a crystalline structure within organisms, which achieves a high refractive index through specific hydrogen bonding patterns and molecular arrangements. Isoxanthopterin can be used for research in materials science and optical engineering [1]. Uses: Scientific research. Group: Natural products. CAS No. 529-69-1. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-W016568. | |
| Isoxazole | Isoxazole is a member of the five-membered heterocycle drug scaffold. Isoxazole has been used as a BET bromodomain inhibitor and can improve β-cell function in a diabetic mouse model. Isoxazole and its derivatives exhibit broad biological activities (such as antimicrobial, antibacterial, antifungal, antiviral, anticancer, anti-inflammatory, immunomodulatory, analgesic, anti-tuberculosis, and anti-diabetic effects). For example, the bicyclic Isoxazole can act as an HSP90 inhibitor, and the tricyclic Isoxazole is promising as a selective multidrug resistance protein (MRP1) inhibitor? [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 288-14-2. Pack Sizes: 10 mM * 1 mL; 25 g; 50 g. Product ID: HY-W010649. | |
| Isoxepac | Isoxepac (HP 549) is a nonsteroidal anti-inflammatory agent (NSAID) with anti-inflammatory, analgesic and antipyretic activity. Isoxepac has been studied in rat, rabbit, dog, rhesus monkey, etc [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HP 549. CAS No. 55453-87-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-W050088. | |
| Isoxsuprine hydrochloride | Isoxsuprine hydrochloride is a beta-adrenergic receptor agonist with K i s of 13.65 μΜ and 3.48 μΜ for myometrial and placcntal beta-adrenergic receptor, respectively. Isoxsuprine hydrochloride is also a NMDA receptor antagonist. Uses: Scientific research. Group: Signaling pathways. CAS No. 579-56-6. Pack Sizes: 10 mM * 1 mL; 200 mg. Product ID: HY-B1270. | |
| Ispinesib | Ispinesib is a specific inhibitor of kinesin spindle protein (KSP) , with a K i app of 1.7 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SB-715992. CAS No. 336113-53-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-50759. | |
| Isradipine | Isradipine (PN 200-110) is an orally active L-type calcium channel blocker. Isradipine, as a powerful peripheral vasodilator, is a dihydropyridine calcium antagonist with selective actions on the heart as well as the peripheral circulation. Isradipine is a potentially viable neuroprotective agent for Parkinson's disease [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PN 200-110. CAS No. 75695-93-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0233. | |
| ISRIB | ISRIB is a brain-penetrant inhibitor of integrated stress response (ISR). Persistent activation of the ISR has been linked to the development of several neurological disorders as ISR represses translation through inhibiting eIF2B. ISRIB inhibits the ISR by promoting the nucleotide exchange activity of eIF2B and recovering the translation, and thus can be used for neurological disorders research [1] [2] [3]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 548470-11-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12495A. | |
| ISRIB (trans-isomer) | ISRIB (trans-isomer) is a potent inhibitor of PERK with an IC50 of 5 nM. ISRIB potently reverses the effects of eIF2? phosphorylation (IC50=5 nM). Uses: Scientific research. Group: Signaling pathways. CAS No. 1597403-47-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12495. | |
| IST5-002 | IST5-002, a potent Stat5a/b inhibitor, selectively inhibits transcriptional activity of Stat5a/b (IC50s: 1.5 ?M for Stat5a, 3.5 ?M for Stat5b). IST5-002 inducs cell apoptotic and death of prostate cancer cells and chronic myeloid leukemia (CML) cells. IST5-002 can be used in the research of prostate cancer and chronic myeloid leukemia (CML)[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: N6-Benzyladenosine-5'-phosphate. CAS No. 13484-66-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-19527. | |
| Istaroxime hydrochloride | Istaroxime hydrochloride is a Na + /K + -ATPase inhibitor ( IC 50 =0.11 μM) and a sarcoplasmic/endoplasmic reticulum calcium ATPase 2 ( SERCA 2 ) activator. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PST2744 hydrochloride. CAS No. 374559-48-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15718A. | |
| Istradefylline | Istradefylline is a very potent, selective and orally active adenosine A2A receptor antagonist with K i of 2.2 nM in experimental models of Parkinson's disease. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KW-6002. CAS No. 155270-99-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-10888. | |
| Istradefylline (Standard) | Istradefylline (Standard) is the analytical standard of Istradefylline. This product is intended for research and analytical applications. Istradefylline is a very potent, selective and orally active adenosine A2A receptor antagonist with K i of 2.2 nM in experimental models of Parkinson's disease. Uses: Scientific research. Group: Signaling pathways. CAS No. 155270-99-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10888R. | |
| ISX-3 | ISX-3 is a potent anti-adipogenic and pro-osteogenic agent. ISX-3 increases the expression of PPAR&gamma. ISX-3 has the potential for the research of osteopenia and osteoporosis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 912789-08-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148694. | |
| ISX-9 | ISX-9 (Isoxazole 9) is a potent inducer of adult neural stem cell differentiation. ISX-9 activates Ca 2+ influx through both voltage-gated Ca 2+ channels and NMDA receptors and increases neuroD expression. ISX-9 also induces cardiomyogenic differentiation of Notch-activated epicardium-derived cells (NECs) [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Isoxazole 9. CAS No. 832115-62-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12323. | |
| IT1t dihydrochloride | IT1t dihydrochloride is a potent CXCR4 antagonist; inhibits CXCL12/CXCR4 interaction with an IC 50 of 2.1 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1092776-63-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101458A. | |
| IT-901 | IT-901 is an orally active and potent NF-?B subunit c-Rel inhibitor with an IC50 of 0.1 ?M, 3 ?M for NF-?B DNA binding and c-Rel DNA binding, respectively. IT-901, a bioactive naphthalenethiobarbiturate derivative, has the potential for human lymphoid tumors and ameliorate graft-versus-host disease (GVHD)[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1584121-99-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124179. | |
| Itacitinib | Itacitinib (INCB039110) is an orally active and selective inhibitor of JAK1 with an IC 50 of 2 nM for human JAK1. Itacitinib shows >20-fold selectivity for JAK1 over JAK2 and >100-fold over JAK3 and TYK2; Itacitinib is used in the research of myelofibrosis [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: INCB039110. CAS No. 1334298-90-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16997. | |
| Itacitinib adipate | Itacitinib adipate is an orally bioavailable and selective JAK1 inhibitor which has been tested for efficacy and safety in a phase II trial in myelofibrosis. Uses: Scientific research. Group: Signaling pathways. CAS No. 1334302-63-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16997A. | |
| Itaconate-alkyne | Itaconate-alkyne (ITalk) is a specific bioorthogonal probe for quantitative and site-specific chemoproteomic profiling of Itaconation in living cells. Itaconate-alkyne, a functional analogue of Itaconate, exhibits comparable antiinflammatory effect with Itaconate and enables the labeling of bona fide targets of Itaconate[1]. Itaconate-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ITalk. CAS No. 2454181-83-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-133870. | |
| Itaconic acid | Itaconic acid, a precursor of polymers, chemicals, and fuels, can be synthesized by many fungi. Itaconic acid also is a macrophage-specific metabolite. Itaconic acid mediates crosstalk between macrophage metabolism and peritoneal tumors. Itaconic acid has anti-inflammatory, anti-microbial and immunomodulatory effect [1] [2] [4] [5]. Uses: Scientific research. Group: Natural products. Alternative Names: Methylenesuccinic acid. CAS No. 97-65-4. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-Y0520. | |
| ITD-1 | ITD-1 is the first selective TGF? receptor inhibitor with an IC50 of 460 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1099644-42-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12704. | |
| ITE | ITE is a potent endogenous agonist of aryl hydrocarbon receptor ( AhR ), binding directly to AHR , with a K i of 3 nM. ITE also has immunosuppressive activity. Uses: Scientific research. Group: Signaling pathways. CAS No. 448906-42-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19317. | |
| Itepekimab | Itepekimab (REGN-3500) is an IgG4 monoclonal antibody against IL-33. Itepekimab reduced airway inflammation and related tissue damage in preliminary clinical studies. Itepekimab has potential effects in asthma, chronic obstructive pulmonary disease (COPD), and atopic dermatitis (AD) [1] [2] [3] [4]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: REGN-3500; SAR-440340. CAS No. 2226742-52-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99673. | |
| ITI-214 | ITI-214 is a potent, CNS-active, orally bioavailable PDE1 inhibitor ( K i of 58 pM) with excellent selectivity against other PDE family members and against a panel of enzymes, receptors, transporters and ion channels. ITI-214 inhibits recombinant full-length human PDE1A, PDE1B and PDE1C with K i s of 33 pM, 380 pM and 35 pM, respectively. ITI-214 shows efficacy in various animal models of motor and cognitive functions [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1642303-38-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-12501A. | |
| ITIC-4F | ITIC-4F is an indacenodithienothiophene (IDTT)-based postfullerene electron acceptor. ITIC-4F has broad applicability in high-efficiency binary and ternary single-junction as well as tandem polymer solar cells (PSCs) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2097998-59-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125831. | |
| Itolizumab | Itolizumab (Anti-Human CD6 Recombinant Antibody) is a humanized recombinant anti-CD6 monoclonal antibody (MAb) targeting the extracellular SRCR distal domain 1 of CD6. Itolizumab reduces T-cell proliferation and inhibits the production of pro-inflammatory cytokines, such as INF-γ, TNFα and IL-6. Itolizumab can be used in the research of psoriasis, rheumatoid arthritis (RA), COVID-19 [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-Human CD6 Recombinant Antibody. CAS No. 1116433-11-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99252. | |
| Itopride hydrochloride | Itopride (HSR803) hydrochloride is a potent dopamine-2 antagonist and an acetylcholine esterase (AChE) inhibitor. Itopride hydrochloride enhances gastric motility through both antidopaminergic and anti-acetylcholinesterasic actions, can be used as a gastrointestinal prokinetic agent. Itopride can be used for researching gastro-esophageal reflux disease (GERD) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HSR803. CAS No. 122892-31-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-B0732. | |
| Itopride N-Oxide | 2-(4-((3, 4-Dimethoxybenzamido)methyl)phenoxy)-N, N-dimethylethan-1-amine oxide is a biological molecule. Uses: Scientific research. Group: Signaling pathways. CAS No. 141996-98-7. Pack Sizes: 1 mg. Product ID: HY-W701323. | |
| Itraconazole | Itraconazole (R51211) is a triazole antifungal agent and a potent and orally active Hedgehog (Hh) signaling pathway antagonist with an IC 50 of ~800 nM. Itraconazole potently inhibits lanosterol 14α-demethylase ( cytochrome P450 enzyme ), thereby inhibits the oxidative conversion of lanosterol to ergosterol. Itraconazole has anticancer and antiangiogenic effects. Itraconazole is a oxysterol-binding protein ( OSBP ) inhibitor [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: R51211. CAS No. 84625-61-6. Pack Sizes: 100 mg; 500 mg. Product ID: HY-17514. | |
| ITSA-1 | ITSA-1 is an activator of histone deacetylase (HDAC), and counteract trichostatin A (TSA)-induced cell cycle arrest, histone acetylation, and transcriptional activation[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 200626-61-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100508. | |
| Iturin A | Iturin A is a cyclic lipid peptide with strong antifungal activity. Iturin A induces ROS explosion and induces apoptosis and autophagy in tumor cells. Iturin A has antitumor activity [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 52229-90-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P2322. | |
| IU1 | IU1 is a special Usp14 inhibitor with an IC 50 of 4-5 μM. Uses: Scientific research. Group: Signaling pathways. CAS No. 314245-33-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13817. | |
| IU1-47 | IU1-47 is a potent and specific USP14 inhibitor with an IC50 of 0.6 ?M. IU1-47 inhibits IsoT/USP5 with an IC50 of 20 ?M. IU1-47 induces tau elimination in cultured neurons[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 670270-31-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122243. | |
| Ivabradine | Ivabradine is a potent and orally active HCN (hyperpolarization-activated cyclic nucleotide-gated) channel blocker that inhibits the cardiac pacemaker current (If). Ivabradine reduces dose-dependently heart rate without modification of blood pressure. Ivabradine shows anticonvulsant, anti-ischaemic and anti-anginal activity [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 155974-00-8. Pack Sizes: 1 mg. Product ID: HY-B0162. | |
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