MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| K-8012 | K-8012, a sulindac (HY-B0008) analog, is a potent antagonist of RXRa. The IC 50 value for K-8012 to inhibit 9-cis-RA-induced Gal4-RXRa-LBD trans-activation were about 9.2 μM. K-8012 exerts improved anticancer activity over sulindac in a RXRa-dependent manner. K-8012 exhibits activity in inhibiting the tRXRa-mediated PI3K/AKT signaling pathway. K-8012 induces apoptosis and inhibits AKT activation by preventing tRXRa from binding to p85a [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1346513-17-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-121435. |  |
| K-975 | K-975 is a potent, selective and orally active TEAD inhibitor, with a strong inhibitory effect against protein-protein interactions between YAP1/TAZ and TEAD. K-975 covalently binds to Cys359 located in the palmitate-binding pocket of TEAD via an acrylamide structure. K-975 exhibits antitumor activity on malignant pleural mesothelioma[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2563855-03-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138565. | |
| Kadsurenone | Kadsurenone. Uses: Scientific research. Group: Natural products. CAS No. 95851-37-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N10663. | |
| Kaempferide | Kaempferide is an orally active flavonol isolated from Hippophae rhamnoides L. Kaempferide has anticancer, anti-inflammatory, antioxidant, antidiabetic, antiobesity, antihypertensive, and neuroprotective activities. Kaempferide induces apoptosis. Kaempferide promotes osteogenesis through antioxidants and can be used in osteoporosis research [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Natural products. Alternative Names: Kaempferol 4'-O-methyl ether. CAS No. 491-54-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15449. | |
| Kaempferitrin | Kaempferitrin is a natural flavonoid, possesses antinociceptive, anti-inflammatory, anti-diabetic, antitumoral and chemopreventive effects, and activates insulin signaling pathway. Uses: Scientific research. Group: Natural products. Alternative Names: Lespedin; Lespenephryl. CAS No. 482-38-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N0628. | |
| Kaempferol | Kaempferol (Kempferol), a flavonoid found in many edible plants, inhibits estrogen receptor α expression in breast cancer cells and induces apoptosis in glioblastoma cells and lung cancer cells by activation of MEK-MAPK. Kaempferol can be uesd for the research of breast cancer [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Kempferol; Robigenin. CAS No. 520-18-3. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-14590. | |
| Kaempferol 7-O-neohesperidoside | Kaempferol 7-O-neohesperidoside is a avonoid glycoside that can be isolated from Litchi chinensis. Kaempferol 7-O-neohesperidoside exhibits significant cytotoxic activity against A549, LAC, Hep-G2, and HeLa cell lines with IC 50 s of 0.53, 7.93, 0.020, and 0.051 μM, respectively [1]. Uses: Scientific research. Group: Natural products. CAS No. 17353-03-6. Pack Sizes: 500 μg; 1 mg. Product ID: HY-N8954. | |
| Kaempferol (Standard) | Kaempferol (Standard) is the analytical standard of Kaempferol. This product is intended for research and analytical applications. Kaempferol (Kempferol), a flavonoid found in many edible plants, inhibits estrogen receptor α expression in breast cancer cells and induces apoptosis in glioblastoma cells and lung cancer cells by activation of MEK-MAPK. Kaempferol can be uesd for the research of breast cancer [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Kempferol(Standard); Robigenin (Standard). CAS No. 520-18-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14590R. | |
| KAG-308 | KAG-308 is a potent selective and orally active agonist of EP4 receptor (a prostaglandin E2 receptor subtype), suppresses colitis and promotes histological mucosal healing, potently inhibits TNF-? production. KAG-308 shows a Ki and an EC50 of 2.57 nM and 17 nM for human EP4 receptor, respectively, more selective over EP1, EP2, EP3 and IP receptor[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1215192-68-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-128686. | |
| Kahweol | Kahweol is one of the consituents of the coffee from Coffea Arabica with anti-inflammatory anti-angiogenic, and anti-cancerous activities. Kahweol inhibits adipogenesis and increase glucose uptake by AMP-activated protein kinase ( AMPK ) activation. Kahweol induces apoptosis. Uses: Scientific research. Group: Natural products. CAS No. 6894-43-5. Pack Sizes: 5 mg; 10 mg; 20 mg. Product ID: HY-N6258. | |
| Kainic acid | Kainic acid is a potent excitotoxic agent. Kainic acid hydrate also is an agonist for a subtype of ionotropic glutamate receptor. Kainic acid induces seizures [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 487-79-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N2309. | |
| Kakkanin | Kakkanin comes from the roots of O. henryi and can be used for the research of anti-inflammatory [1]. Uses: Scientific research. Group: Natural products. CAS No. 63770-91-2. Pack Sizes: 1 mg. Product ID: HY-N9375. | |
| KALA | KALA is an amphiphilic peptide that forms an α-helical structure at physiological pH. KALA modifies a plasmid DNA-encapsulating liposomal membrane and is used as a fusogenic peptide in order to achieve effective liver targeting and transfection of DNA via galactose receptors [1]. Uses: Scientific research. Group: Peptides. CAS No. 187987-64-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P2530. | |
| Kallikrein 5-IN-2 | Kallikrein 5-IN-2 (compound 21) is a selective Kallikrein KLK5 inhibitor (pIC 50 =7.1). KLK5 inhibition may normalise epidermal shedding and reduce the associated inflammation and itching [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2361160-57-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-148949. | |
| Kallikrein, Porcine pancreas | Kallikrein, Porcine pancreas (kininogenase) is capable of forming the kallikrenase kalinin system (KKS) in plasma and tissues, producing bradykinin and kalin peptides, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: kininogenase; SK-827. CAS No. 9001-1-8. Pack Sizes: 100 mg; 250 mg. Product ID: HY-P2795. | |
| KAN0438757 | KAN0438757 is a potent and selective inhibitor of the metabolic kinase PFKFB3 with an IC50 of 0.19 ?M[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1451255-59-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112808. | |
| Kanamycin | Kanamycin (Kanamycin A) is an orally active antibacterial (gram-negative/positive bacteria) agent, inhibits translocation and causes misencoding by binding to the 70 S ribosomal subunit. Kanamycin shows good inhibitory activity to both M. tuberculosis (sensitive and drug-resistant ) and K. pneumonia , which can be used in studies of tuberculosis and pneumonia [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Kanamycin A. CAS No. 59-01-8. Pack Sizes: 100 mg; 200 mg. Product ID: HY-16566. | |
| Kanamycins sulfate | Kanamycins sulfate is a broad-spectrum antibiotic, can be used in certain severe staphylococcal or Gram-negative bacillary infections. Kanamycin sulfate has certain ototoxicity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 70560-51-9. Pack Sizes: 1 g; 5 g. Product ID: HY-W040128. | |
| Kanamycin sulfate | Kanamycin (Kanamycin A) sulfate is an orally active antibacterial (gram-negative/positive bacteria) agent, inhibits translocation and causes misencoding by binding to the 70 S ribosomal subunit. Kanamycin sulfate shows good inhibitory activity to both M. tuberculosis (sensitive and drug-resistant ) and K. pneumonia , which can be used in studies of tuberculosis and pneumonia [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Kanamycin A sulfate. CAS No. 25389-94-0. Pack Sizes: 10 mM * 1 mL; 200 mg; 1 g; 5 g. Product ID: HY-16566A. | |
| Kanosamine hydrochloride | Kanosamine hydrochloride is an antibiotic which inhibits the growth of plant-pathogenic oomycetes, certain fungi and a few bacterial species. Kanosamine inhibits Phytophthora medicaginis M2913 and Aphanomyces euteiches WI-98 with MIC s of 25 and 60 μg/mL, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 57649-10-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-112176. | |
| κ-Carrageenan | κ-Carrageenan is a natural polymer which predominantly available in red seaweeds. κ-Carrageenan is an effective agent carrier to deliver curcumin in cancer cells and to induce apoptosis. κ-carrageenan serves as a potential inflammatory agent that magnifies existing intestinal inflammation [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: K-Carrageenan Karra Type. CAS No. 11114-20-8. Pack Sizes: 10 g; 25 g. Product ID: HY-138962. | |
| Karanjin | Karanjin is an orally active furanoflavonoid which can be isolated from several Leguminosae. Karanjin exhibits evident anti-diabetic, anti-cancer, anti-inflammatory, antioxidant, anticolitis, anti-ulcer, anti-Alzheimer properties and multiple insect repellent/insecticidal, acaricide properties, suggesting the potential of Karanjin to be applied to relevant research [1]. Uses: Scientific research. Group: Natural products. CAS No. 521-88-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N2534. | |
| Kartogenin | Kartogenin (KGN) is an inducer of chondrogenic tissue formation ( EC 50 : 100 nM). Kartogenin induces chondrogenesis by binding to fibrin A, disrupting its interaction with the transcription factor core binding factor beta subunit (CBFβ), and by modulating the CBFβ-RUNX1 transcriptional program. Kartogenin also promotes tendon-bone junction (TBJ) wound healing by stimulating collagen synthesis. Kartogenin is widely used in cell-free therapy in the field of regeneration for cartilage regeneration and protection, tendon-bone healing, wound healing and limb development. Kartogenin promotes cartilage repair, coordinates limb development, and is also used in osteoarthritis (OA) research [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KGN. CAS No. 4727-31-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16268. | |
| Kartogenin sodium | Kartogenin (KGN) sodium is an inducer of chondrogenic tissue formation ( EC 50 : 100 nM). Kartogenin sodium induces chondrogenesis by binding to fibrin A, disrupting its interaction with the transcription factor core binding factor beta subunit (CBFβ), and by modulating the CBFβ-RUNX1 transcriptional program. Kartogenin sodium also promotes tendon-bone junction (TBJ) wound healing by stimulating collagen synthesis. Kartogenin sodium is widely used in cell-free therapy in the field of regeneration for cartilage regeneration and protection, tendon-bone healing, wound healing and limb development. Kartogenin sodium promotes cartilage repair, coordinates limb development, and is also used in osteoarthritis (OA) research [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KGN sodium. CAS No. 1401168-39-5. Pack Sizes: 5 mg; 10 mg; 50 mg. Product ID: HY-16268A. | |
| Kasugamycin hydrochloride | Kasugamycin hydrochloride (Ksg hydrochloride) is an antibiotic which binds both the 30S and 70S ribosome but not isolated 50S subunits. Kasugamycin hydrochloride (Ksg hydrochloride) mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Ksg hydrochloride. CAS No. 19408-46-9. Pack Sizes: 25 mg; 50 mg. Product ID: HY-B1864A. | |
| Kasugamycin hydrochloride hydrate | Kasugamycin (Ksg) hydrochloride hydrate is an antibiotic that binds to 30s and 70s ribosomes but not to the 50s subunit, and has anti-infective activity. Kasugamycin hydrochloride hydrate mimics mRNA nucleotides, disrupts tRNA binding and inhibits canonical translation initiation. Kasugamycin hydrochloride hydrate increases the sensitivity of mycobacteria to Rifampicin (HY-B0272) in vitro and in mouse infection models [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ksg hydrochloride hydrate. CAS No. 200132-83-8. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-B1864B. | |
| KAT8-IN-1 | KAT8-IN-1 is a lysine (K) acetyltransferase 8 (KAT8) inhibitor, with IC50s of 141 ?M (KAT8), 221 ?M (KAT2B), 106 ?M (KAT3B), respectively. KAT8 inhibits histone acetyltransferases (HATs), and could result in disease states, such as cancer or inflammatory diseases[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 605-62-9. Pack Sizes: 10 mM * 1 mL; 5 g; 10 g. Product ID: HY-W015239. | |
| Katacalcin | Katacalcin (PDN 21) is a potent plasma calcium-lowering peptide [1]. Uses: Scientific research. Group: Peptides. Alternative Names: PDN 21. CAS No. 85916-47-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P0149. | |
| Kaurenoic acid | Kaurenoic acid is a diterpene derived from Sphagneticola trilobata. Kaurenoic acid has antibacterial, anti-inflammatory, anticonvulsant, analgesic, and aortic vasodilating effects [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 6730-83-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 20 mg. Product ID: HY-N1469. | |
| Kavain | Kavain is a class of kavalactone isolated from Piper methysticum , which has anxiolytic properties in animals and humans. Kavain positively modulated γ-Aminobutyric acid type A (GABAA) receptor [1]. Uses: Scientific research. Group: Natural products. CAS No. 3155-48-4. Pack Sizes: 10 mM * 1 mL; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-N2096. | |
| (+)-Kavain | (+)-Kavain, a main kavalactone extracted from Piper methysticum , has anticonvulsive properties, attenuating vascular smooth muscle contraction through interactions with voltage-dependent Na + and Ca 2+ channels [1]. (+)-Kavain is shown to bind at the α4β2δ GABA A receptor and potentiate GABA efficacy [2]. (+)-Kavain is used as a treatment for inflammatory diseases, its anti-inflammatory action has been widely studied [4]. Uses: Scientific research. Group: Natural products. CAS No. 500-64-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-B1671. | |
| KB-05 | KB-05 is an electrophilic fragment molecule that can be used in DIA-based quantitative chemical proteomic screening studies. Uses: Scientific research. Group: Signaling pathways. CAS No. 1956368-15-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-149461. | |
| KB-0742 | KB-0742 is a potent, selective and orally active CDK9 inhibitor with an IC 50 of 6 nM for CDK9/cyclin T1. KB-0742 is selective for CDK9/cyclin T1 with >50-fold selectivity over other CDK kinases. KB-0742 has potent anti-tumor activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2416873-83-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137478. | |
| KB-0742 dihydrochloride | KB-0742 dihydrochloride is a potent, selective and orally active CDK9 inhibitor with an IC 50 of 6 nM for CDK9/cyclin T1. KB-0742 dihydrochloride is selective for CDK9/cyclin T1 with >50-fold selectivity over other CDK kinases. KB-0742 dihydrochloride has potent anti-tumor activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2416874-75-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137478A. | |
| KC01 | KC01 is an effective inhibitor of ABHD16A , with IC 50 s of 90 nM for hABHD16A and 520 nM for mABHD16A. KC01 significantly reduces lyso-PSs, and decreases lyso-PS and LPS-induced cytokine production in mouse macrophages [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1646795-59-6. Pack Sizes: 1 mg. Product ID: HY-120299. | |
| KC7F2 | KC7F2 is a potent hypoxia inducible factor-1 (HIF-1) pathway inhibitor with an IC50 of 20 ?M in LN229-HRE-AP cells, and with potential as a cancer therapy agent[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 927822-86-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18777. | |
| KCC009 | KCC009, a transglutaminase 2 (TG2) inhibitor, induces p53-independent radiosensitization[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 744198-19-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123290. | |
| KCC-07 | KCC-07 is a potent, selective and brain-penetrant MBD2 (methyl-CpG-binding domain protein 2) inhibitor. KCC-07 prevents binding of MBD2 to methylated DNA and activates brain specific angiogenesis inhibitor 1 (BAI1) inducing anti-proliferative BAI1/p53/p21 signaling. Anticancer activity[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 315702-75-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-131031. | |
| KDM5A-IN-1 | KDM5A-IN-1 is a potent, orally bioavailable pan-histone lysine demethylases 5 (KDM5) inhibitor with IC50s of 45 nM, 56 nM and 55 nM for KDM5A, KDM5B and KDM5C, respectively, and with an EC50 value of 960 nM for PC9 H3K4Me3. KDM5A-IN-1 is significantly less potent against other KDM5B enzymes (1A, 2B, 3B, 4C, 6A, 7B)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1905481-36-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100014. | |
| KDM5-C70 | KDM5-C70 is an ethyl ester derivative of KDM5-C49 and a potent, cell-permeable and pan-KDM5 histone demethylase inhibitor. KDM5-C70 has an antiproliferative effect in myeloma cells, leading to genome-wide elevation of H3K4me3 levels[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1596348-32-1. Pack Sizes: 10 mM * 1 mL; 25 mg; 100 mg; 250 mg. Product ID: HY-120400. | |
| Kdo2-Lipid A ammonium | Kdo2-Lipid A ammonium is a chemically defined lipopolysaccharide (LPS) with endotoxin activity equal to LPS. Kdo2-Lipid A ammonium is highly selective for TLR4. Kdo2-Lipid A ammonium stimulates the release of both TNF and PGE2 [1]. Uses: Scientific research. Group: Natural products. CAS No. 1246298-62-3. Pack Sizes: 1 mg. Product ID: HY-N8277. | |
| KDOAM-25 citrate | KDOAM-25 citrate is a potent and highly selective histone lysine demethylases 5 (KDM5) inhibitor with IC50s of 71 nM, 19 nM, 69 nM, 69 nM for KDM5A, KDM5B, KDM5C, KDM5D, respectively. KDOAM-25 citrate increases global H3K4 methylation at transcriptional start sites and impairs proliferation in multiple myeloma MM1S cells[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2448475-08-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-102047B. | |
| Kdo Azide | Kdo Azide is a click chemistry reagent containing an azide. Kdo Azide is a metabolic labeling reagent[1]. Kdo Azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1380099-68-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-151685. | |
| Kebuzone | Kebuzone is a non-steroidal anti-inflammatory substance that may be studied in inflammatory diseases such as thrombophlebitis and rheumatoid arthritis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ketazone; Ketophenylbutazone. CAS No. 853-34-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111284. | |
| Keliximab | Keliximab (SB-210396) is a chimeric human/macaque IgG1 anti-CD4 monoclonal antibody with a K i value of 1.0 nM for soluble CD4. Keliximab blocks T cell proliferation and inhibits IL-2 production. Keliximab can be used for cancer research [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: SB-210396; IDEC CE9.1. CAS No. 174722-30-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99680. | |
| Kemptide | Kemptide is a synthetic heptapeptide that acts as a specific substrate for cAMP-dependent protein kinase ( PKA ). Uses: Scientific research. Group: Peptides. CAS No. 65189-71-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P0248. | |
| Kenpaullone | Kenpaullone is a potent inhibitor of CDK1/cyclin B and GSK-3β , with IC 50 s of 0.4 μM and 23 nM, and also inhibits CDK2/cyclin A, CDK2/cyclin E, and CDK5/p25 with IC 50 s of 0.68 μM, 7.5 μM, 0.85 μM, respectively. Kenpaullone, a small molecule inhibitor of KLF4 , reduces self-renewal of breast cancer stem cells and cell motility in vitro. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 9-Bromopaullone; NSC-664704. CAS No. 142273-20-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12302. | |
| KER047 | ALK2-IN-4 is a potent ALK2 inhibitor extracted from patent WO2020086963A1, compound Formula I free base [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ALK2-IN-4. CAS No. 2248154-85-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136773. | |
| KER047 succinate | ALK2-IN-4 succinate is a potent ALK2 inhibitor extracted from patent WO2020086963A1, compound Formula I free base [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ALK2-IN-4 succinate. CAS No. 2416307-25-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136773A. | |
| Keracyanin chloride | Keracyanin chloride (Cyanidin 3-rutinoside chloride), an anthocyanin, has antioxidant activity. Keracyanin chloride inhibits malonaldehyde formation in oxidized calf thymus DNA [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Cyanidin 3-rutinoside chloride; Cyanidin 3-O-rutinoside chloride; Sambucin chloride. CAS No. 18719-76-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-105935. | |
| Keratinase | Keratinase (KerA) is a protease that are able to degrade keratins into amino acids [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KerA. CAS No. 37341-53-0. Pack Sizes: 500 U. Product ID: HY-E70193. | |
| Ketanserin | Ketanserin is a selective 5-HT2 receptor antagonist. Ketanserin also blocks hERG current ( I hERG ) in a concentration-dependent manner ( IC 50 =0.11 μM). Uses: Scientific research. Group: Signaling pathways. Alternative Names: R41468. CAS No. 74050-98-9. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-10562. | |
| Ketanserinol | Ketanserinol (R 46742) is a metabolite of Ketanserin (HY-10562). Ketanserinol is a competitive antagonist of the effects of 5-HT (HY-B1473A) in both arteries. The K B values are 6.5 for large coronary arteries and 6.4 for pulmonary arteries [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R 46742. CAS No. 76330-73-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-121208. | |
| Ketanserin tartrate | Ketanserin (R41468) tartrate is a selective 5-HT2 receptor antagonist. Ketanserin tartrate also blocks hERG current ( I hERG ) in a concentration-dependent manner ( IC 50 =0.11 μM). Uses: Scientific research. Group: Signaling pathways. Alternative Names: R41468 tartrate. CAS No. 83846-83-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-10562A. | |
| Ketoconazole | Ketoconazole (R-41400) is an imidazole anti-fungal agent, a CYP3A4 and CYP24A1 inhibitor. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ketoconazol; R 41400. CAS No. 65277-42-1. Pack Sizes: 10 mM * 1 mL; 100 mg; 1 g; 5 g. Product ID: HY-B0105. | |
| (-)-Ketoconazole | (-)-Ketoconazole ((-)-R 41400) is one of the enantiomer of Ketoconazole. Ketoconazole is a racemic mixture of two enantiomers, levoketoconazole ((2S,4R)-(-)-ketoconazole) and dextroketoconazole ((2R,4S)-(+)-ketoconazole). Uses: Scientific research. Group: Signaling pathways. Alternative Names: (-)-Ketoconazol; (-)-R 41400. CAS No. 142128-57-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0105B. | |
| (+)-Ketoconazole | (+)-Ketoconazole ((+)-R 41400) is an imidazole anti-fungal agent, a CYP3A4 inhibitor. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (+)-Ketoconazol; (+)-R 41400. CAS No. 142128-59-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0105A. | |
| Ketodarolutamide | Ketodarolutamide (ORM-15341) is a potent and full antagonist for human AR (hAR) with IC50 values of 38 nM as shown by transactivation assays in AR-HEK293 cells stably expressing full-length hAR and an androgen-responsive luciferase reporter gene construct. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 1896953; ORM-15341. CAS No. 1297537-33-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-19337. | |
| Ketoisophorone | Ketoisophorone (4-Oxoisophorone) is a key intermediate in the synthesis of carotenoids and flavouring agents. Ketoisophorone is an industrially important cyclic endione [1]. Uses: Scientific research. Group: Natural products. Alternative Names: 4-Oxoisophorone. CAS No. 1125-21-9. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-107832. | |
| Ketone monoester | Ketone monoester is an orally available ketone monoester that serves as a source of nutritional ketones. Ketone monoester increases plasma beta-hydroxybutyrate, acetoacetate, blood glucose, blood sodium, and blood creatinine levels in mouse models. Ketone monoester has the potential to improve athletic performance and endurance in animals. Ketone monoester partially prevents myasthenia in septic mice. Ketone monoester may also be used to study Parkinson's disease or diabetes [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1208313-97-6. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg. Product ID: HY-15344. | |
| Ketoprofen | Ketoprofen (RP-19583) is a non-steroidal anti-inflammatory agent. Ketoprofen can inhibits the activity of cyclooxygenase with IC 50 values of 2 nM ( COX-1 ) and 26 nM ( COX-2 ). which is potential in the research of inflammation, immunology, and metabolic disease such as obesity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RP-19583. CAS No. 22071-15-4. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0227. | |
| Ketorolac | Ketorolac (RS37619) is a non-steroidal anti-inflammatory drug (NSAID), acting as a nonselective COX inhibitor, with IC 50 s of 20 nM for COX-1 and 120 nM for COX-2. Ketorolac tromethamine is used as 0.5% ophthalmic solution for the research of allergic conjunctivitis, cystoid macular edema, intraoperative miosis, and postoperative ocular inflammation and pain. Ketorolac tromethamine is also a DDX3 inhibitor that can be used for cancer research [1] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RS37619. CAS No. 74103-06-3. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B0580. | |
| Ketorolac tromethamine salt | Ketorolac tromethamine salt (RS37619 tromethamine salt) is a non-steroidal anti-inflammatory agent, acting as a nonselective COX inhibitor, with IC 50 s of 20 nM for COX-1 and 120 nM for COX-2. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ketorolac Tromethamine; Ketorolac tris salt; RS37619 tromethamine salt. CAS No. 74103-07-4. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0138. | |
| Ketotifen | Ketotifen (HC 20-511) is an orally active second-generation noncompetitive histamine 1 (H1) receptor blocker and mast cell stabilizer. Ketotifen can block 6-phosphogluconate dehydrogenase (PGD) in vitro. Ketotifen also has antiviral activity against SARS-CoV-2 and Influenza virus. Ketotifen can be used to the research of autoimmune encephalomyelitis (EAE) and asthma attack prevention [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: HC 20-511. CAS No. 34580-13-7. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-B0157. | |
| Ketotifen fumarate | Ketotifen (HC 20-511) fumarate is an orally active second-generation noncompetitive histamine 1 (H1) receptor blocker and mast cell stabilizer. Ketotifen fumarate can block 6-phosphogluconate dehydrogenase (PGD) in vitro. Ketotifen fumarate also has antiviral activity against SARS-CoV-2 and Influenza virus. Ketotifen fumarate can be used to the research of autoimmune encephalomyelitis (EAE) and asthma attack prevention [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: HC 20511 fumarate. CAS No. 34580-14-8. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B0157A. | |
| KF38789 | KF38789 is a selective inhibitor of P-selectin-PSGL-1 binding. KF38789 inhibits the binding of U937 cells to immobilized P-selectin immunoglobulin G chimeric protein (P-selectin-Ig) with an IC50 value of 1.97 ?M[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 257292-29-8. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-103358. | |
| KG5 | KG5 is an orally active dual PDGFRβ and B-Raf allosteric inhibitor. KG5 also inhibits Flt3 , KIT and c-Raf. KG5 has anticancer, antiangiogenic activities [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 877874-85-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15198. | |
| KG-501 | KG-501 is a CREB inhibitor, with an IC50 of 6.89 ?M. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Naphthol AS-E phosphate. CAS No. 18228-17-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-103299. | |
| KGP94 | KGP94 is a selective inhibitor of cathepsin L with an IC50 of 189 nM[1]. KGP94 inhibits migration and invasion of metastatic carcinoma and shows low cytotoxicity (GI50=26.9 μM) against various human cell lines[2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1131456-28-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-118762. | |
| KH-3 | KH-3 is a potent RNA-binding protein Hu antigen R (HuR) inhibitor with an IC 50 value of 0.35 μM. KH-3 has anti-proliferative activity. KH-3 suppresses breast cancer cell invasion as well as delays the initiation of lung colonies by disrupting HuR-FOXQ1 mRNA interaction [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1215115-03-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134601. | |
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