MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Neboglamine hydrochloride | Neboglamine (CR-2249, XY-2401) hydrochloride is an orally active NMDA receptor glycine site positive modulator that can be used in schizophrenia research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CR-2249 hydrochloride; XY-2401 hydrochloride. CAS No. 2759182-59-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114753A. |  |
| Necitumumab | Necitumumab is a human IgG monoclonal antibody directed against EGFR. Necitumumab can be used for research of NSCLC, colorectal cancer, etc [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 906805-06-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9964. | |
| Necroptosis-IN-1 | Necroptosis-IN-1, an analog of Necrostatin-1, is a potent necroptosis inhibitor. Necroptosis-IN-1 is a RIPK inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1391980-92-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-135826. | |
| Necroptosis-IN-3 | Necroptosis-IN-3 (Compound 69) is a necroptosis inhibitor that inhibits TNF-α induced necroptosis [1]. Necroptosis-IN-3 (Compound STX1638) also inhibits 11β-HSD1 [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 547698-18-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148454. | |
| Necrostatin-1 | Necrostatin-1 (Nec-1) is a potent and cross the blood-brain barrier necroptosis inhibitor with an EC 50 of 490 nM in Jurkat cells. Necrostatin-1 inhibits RIP1 kinase ( EC 50 =182 nM). Necrostatin-1 is also an IDO inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Nec-1. CAS No. 4311-88-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15760. | |
| Necrostatin-1 (inactive control) | Necrostatin-1 (Nec-1) (inactive control) is an inactive analog of Necrostatin-1 (HY-15760). Necrostatin-1 is a potent necroptosis inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Nec-1 (inactive control). CAS No. 64419-92-7. Pack Sizes: 1 mg. Product ID: HY-121954. | |
| Necrostatin 2 | Necrostatin 2 is a potent necroptosis inhibitor. EC 50 for inhibition of necroptosis in FADD-deficient Jurkat T cells treated with TNF-α is 0.05 μM. Necrostatin 2 is also a RIPK1 inhibitor. Uses: Scientific research. Group: Signaling pathways. CAS No. 852391-19-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-14622. | |
| Necrostatin 2 racemate | Necrostatin 2 racemate (Nec-1S), the Necrostatin-1 (HY-15760) stable, is a potent and specific RIPK1 inhibitor lacking the IDO-targeting effect [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Necrostatin 1S; Nec-1S; 7-Cl-O-Nec1. CAS No. 852391-15-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-14622A. | |
| Necrostatin-7 | Necrotatin-7 (Nec-7) is a potent necroptosis inhibitor with an EC 50 of 10.6 μM. Necrotatin-7 does not inhibit recombinant RIP1 kinase [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Nec-7. CAS No. 351062-08-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117200. | |
| Nedaplatin | Nedaplatin (NSC 375101D) is a derivative of cisplatin and DNA damage agent. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NSC 375101D. CAS No. 95734-82-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13700. | |
| Nedizantrep | GDC-6599 is an orally active TRPA1 inhibitor, with IC 50 values of 5.3 nM in humans, 6.6 nM in rats, 9.3 nM in dogs, 7.2 nM in monkeys, and 15 nM in guinea pigs. GDC-6599 can be used in the research of neuropathic pain and respiratory diseases such as asthma and chronic cough [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GDC-6599. CAS No. 2376824-99-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg. Product ID: HY-156684. | |
| Nedocromil | Nedocromil suppresses the action or formation of multiple mediators, including histamine , leukotriene C 4 ( LTC 4 ), and prostaglandin D 2 ( PGD 2 ). Uses: Scientific research. Group: Signaling pathways. Alternative Names: FPL 59002. CAS No. 69049-73-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13448. | |
| Nefazodone | Nefazodone is an orally active phenylpiperazine antidepressant. Nefazodone can potently and selectively block postsynaptic 5-HT 2A receptors , and moderately inhibit 5-HT and noradrenaline reuptake. Nefazodone can also relieve the adverse effects of stress on the the immune system of mice. Nefazodone has a high affinity for CYP3A4 isoenzyme, which indicates that it has certain risk of agent-agent interaction [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 83366-66-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119209. | |
| Nefazodone hydrochloride | Nefazodone hydrochloride (BMY-13754) is a potent and selective 5HT2A ( K i =5.8 nM) antagonist with moderate inhibition of 5-HT and noradrenaline uptake ( IC 50 of 290 and 300 nM, respectively). Nefazodone hydrochloride is a phenylpiperazine antidepressant with less alpha-adrenergic blocking activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMY-13754; MJ-13754-1. CAS No. 82752-99-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-B1396. | |
| Neferine | Neferine is a major bisbenzylisoquinline alkaloid. Neferine strongly inhibits NF-κB activation. Uses: Scientific research. Group: Natural products. Alternative Names: (-)-Neferine. CAS No. 2292-16-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N0441. | |
| Nefiracetam | Nefiracetam is a GABAergic, cholinergic, and monoaminergic neuronal systems enhancer for Ro 5-4864-induced convulsions. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DM9384; DZL-221. CAS No. 77191-36-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-B0340. | |
| Neflamapimod | Neflamapimod (VX-745) is a potent, blood-brain barrier penetrant, highly selective inhibitor of p38α inhibitor with an IC 50 for p38α of 10 nM and for p38β of 220 nM. Neflamapimod (VX-745) possesses anti-inflammatory activity. Uses: Scientific research. Group: Signaling pathways. Alternative Names: VX-745. CAS No. 209410-46-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-10328. | |
| Nefopam hydrochloride | Nefopam hydrochloride (Fenazoxine hydrochloride) is a centrally-acting but non-opioid analgesic drug, for the relief of moderate to severe pain. Nefopam hydrochloride targets β-catenin protein level in mesenchymal cells in-vitro and in-vivo [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Fenazoxine hydrochloride. CAS No. 23327-57-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-B1057. | |
| Neihulizumab | Neihulizumab (ALTB-168) is an immune checkpoint agonistic antibody that binds to human CD162 (PSGL-1) , leading to downregulation of activated T-cells. Neihulizumab can be uesd for steroid-refractory acute graft-versus-host-disease (SR-aGVHD), psoriasis, psoriatic arthritis and ulcerative colitis research [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ALTB-168; Anti-PSGL1/CD162 Reference Antibody (neihulizumab). CAS No. 2158362-38-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99378. | |
| Nelarabine | Nelarabine (506U78) is a nucleoside analogue and can be used for the research of T cell acute lymphoblastic leukemia (T-ALL) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 506U78; GW 506U78; Nelzarabine. CAS No. 121032-29-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13701. | |
| Nelfinavir | Nelfinavir (AG-1341) is a potent and orally bioavailable HIV-1 protease inhibitor ( K i =2 nM) for HIV infection. Nelfinavir is a broad-spectrum, anticancer agent [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AG1341. CAS No. 159989-64-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-15287. | |
| Nelfinavir Mesylate | Nelfinavir Mesylate (AG 1343 Mesylate) is a potent and orally bioavailable HIV-1 protease inhibitor ( K i =2 nM) for HIV infection. Nelfinavir Mesylate (AG 1343 Mesylate) is a broad-spectrum, anticancer agent [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AG 1343 Mesylate. CAS No. 159989-65-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15287A. | |
| Nelistotug | Nelistotug (GSK 6097608; GSK6097608) is a human IgG1κ antibody targeting CD96 [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2645437-82-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990053. | |
| Nelonemdaz | Nelonemdaz (Salfaprodil free base) is an NR2B-selective and uncompetitive antagonist of N-methyl-D-aspartate (NMDA). Nelonemdaz is also a free radical scavenger. Nelonemdaz has excellent neuroprotection against NMDA- and free radical-induced cell death [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Salfaprodil free base; Neu2000. CAS No. 640290-67-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-106408. | |
| Nelonemdaz potassium | Nelonemdaz (Salfaprodil) potassium is an NR2B-selective and uncompetitive antagonist of N-methyl-D-aspartate (NMDA). Nelonemdaz potassium is also a free radical scavenger. Nelonemdaz potassium has excellent neuroprotection against NMDA- and free radical-induced cell death [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Salfaprodil; Neu2000 potassium. CAS No. 916214-57-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-106408A. | |
| Nelotanserin | Nelotanserin is a potent 5-HT 2A inverse agonist, a moderately potent 5-HT 2C partial inverse agonist and a weak 5-HT 2B inverse agonist, with IC 50 s of 1.7, 79, 791 nM in IP accumulation assays, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: APD125. CAS No. 839713-36-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10559. | |
| Nemiralisib | Nemiralisib (GSK2269557 free base) is a potent and highly selective PI3Kδ inhibitor with a pK i of 9.9. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GSK2269557 free base. CAS No. 1254036-71-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19535A. | |
| Nemolizumab | Nemolizumab (CIM331) is a humanized monoclonal antibody that targets the human interleukin-31 receptor a, preventing interleukin-31 ( IL-31 ) from binding to its receptor and the subsequent signaling. Nemolizumab can help reduce itching and sleep disturbances, and it is being studied for atopic dermatitis (AD) [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: CIM331. CAS No. 1476039-58-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99162. | |
| Nemonapride | Nemonapride is a highly potent dopamine D 2 receptor antagonist with a K i of 0.06 nM. Nemonapride also activates 5-HT 1A receptor with an IC 50 of 34 nM. Nemonapride is an antipsychotic that readily passes through the blood brain barrier and exhibits potent neuroleptic effects in animals [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: YM-09151-2; Emonapride. CAS No. 75272-39-8. Pack Sizes: 1 mg. Product ID: HY-103415. | |
| Nemonoxacin | Nemonoxacin (TG-873870) is an orally active and potent broad-spectrum antibiotic. Nemonoxacin shows good inhibitory activity against different species of staphylococci, streptococci, and enterococci, Neisseria gonorrhoeae , and Haemophilus influenza. Nemonoxacin can be used in the study of bacterial infections and community-acquired pneumonia [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TG-873870. CAS No. 378746-64-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-14956. | |
| Nemonoxacin malate | Nemonoxacin (TG-873870) malate is a nonfluorinated quinolone antibiotic. Nemonoxacin malate has broad-spectrum activity against Gram-positive, Gram-negative and atypical pathogens. Nemonoxacin malate can inhibit drug-resistant Streptococcus pneumoniae and (HY-121544) Methicillin -resistant Staphylococcus aureus. Nemonoxacin malate can be used for the research of community-acquired pneumonia [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TG-873870 malate. CAS No. 951163-60-3. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-111023. | |
| Nemtabrutinib | ARQ 531 (MK-1026) is a reversible non-covalent and orally active inhibitor of Brutons Tyrosine Kinase ( BTK ), with IC 50 s of 0.85 nM and 0.39 nM for WT-BTK and C481S-BTK, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ARQ-531; MK-1026. CAS No. 2095393-15-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112215. | |
| Nemvaleukin alfa | Nemvaleukin alfa (ALKS 4230) is a IL-2 fusion protein that selectively binds to intermediate-affinity IL-2R. Nemvaleukin alfa is an activator of NK and effector T cells. Nemvaleukin alfa can be used for research of cancer [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ALKS 4230; RDB-1450. CAS No. 2315268-27-8. Pack Sizes: 500 μg; 1 mg; 5 mg; 10 mg. Product ID: HY-P99752. | |
| Neocuproine | Neocuproine is an organic compound commonly used as a complexing reagent and copper ion detector. It can form stable complexes with copper ions, and can play a catalytic role in certain chemical reactions and analytical methods. In addition, this compound is also widely used in some biomedical fields, such as in the study of copper metabolism disorders and neurodegenerative diseases. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 484-11-7. Pack Sizes: 5 g; 10 g. Product ID: HY-W004563. | |
| Neodiosmin | Neodiosmin is a flavone glycoside isolated from the leaves of Citrus aurantium [1]. Uses: Scientific research. Group: Natural products. CAS No. 38665-01-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N4122. | |
| Neoeriocitrin | Neoeriocitrin, isolated from Drynaria Rhizome, shows activity on proliferation and osteogenic differentiation in MC3T3-E1. Neoeriocitrin is a potent acetylcholinesterase (AChE) inhibitor [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 13241-32-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N4119. | |
| Neohesperidin | Neohesperidin is a flavonoid compound abundant in citrus plants with antioxidant and anti-inflammatory effects. Neohesperidin can upregulate the Wnt/β-catenin signaling pathway, enhance the nuclear translocation of β-catenin and the differentiation of bone marrow stromal cells [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Hesperetin 7-O-neohesperidoside. CAS No. 13241-33-3. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-N0101. | |
| Neohesperidin dihydrochalcone | Neohesperidin dihydrochalcone is a synthetic glycoside chalcone, is added to various foods and beverages as a low caloric artificial sweetener. Uses: Scientific research. Group: Natural products. Alternative Names: Neohesperidin DC; NHDC. CAS No. 20702-77-6. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-N0154. | |
| Neoline | Neoline (Bullatine B)) is the active ingredient of the active ingredient (PA), which can be used to cure the disease. Neoline Flow Suppression Nav1.7 Electrical Flow Control (VGSC), Improve diabetes mechanical pain sensitivity. Neoline has a list of compounds that can be used, research on its use, and the quality of its processing during processing in pain. Uses: Scientific research. Group: Natural products. Alternative Names: Bullatine B. CAS No. 466-26-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N0478. | |
| Neomangiferin | Neomangiferin is a natural C-glucosyl xanthone isolated from m the dried rhizome of Anemarrhena asphodeloides. Neomangiferin has significant therapeutic effects on high-fat diet-induced nonalcoholic fatty liver disease (NAFLD) in rats [1]. Uses: Scientific research. Group: Natural products. CAS No. 64809-67-2. Pack Sizes: 5 mg; 10 mg; 20 mg. Product ID: HY-N0723. | |
| (+)-Neomenthol | (+)-Neomenthol is a potent miticide. (+)-Neomenthol shows acaricidal activitie with LD 50 values of 0.32, 0.256 μg/mL for Dermatophagoides farinae and Dermatophagoides pteronyssinus , respectively [1]. Uses: Scientific research. Group: Natural products. CAS No. 2216-52-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-135286A. | |
| Neomycin sulfate | Neomycin sulfate, an aminoglycoside antibiotic, exerts antibacterial activity through irreversible binding of the nuclear 30S ribosomal subunit, thereby blocking bacterial protein synthesis. Neomycin sulfate is a known phospholipase C (PLC) inhibitor. Neomycin sulfate potently inhibits both nuclear translocation of angiogenin and angiogenin-induced cell proliferation and angiogenesis [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 1405-10-3. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B0470. | |
| Neopterin | Neopterin (D-(+)-Neopterin), a catabolic product of guanosine triphosphate (GTM) , serves as a marker of cellular immune system activation. Uses: Scientific research. Group: Natural products. Alternative Names: D-(+)-Neopterin; D-erythro-Neopterin. CAS No. 2009-64-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-W040055. | |
| Neoruscogenin | Neoruscogenin, a member of the steroidal sapogenin family, is a high-affinity agonist of the nuclear receptor RORα (NR1F1) ( EC 50 = 0.11 μM) [1]. Uses: Scientific research. Group: Natural products. CAS No. 17676-33-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N2253. | |
| Neosolaniol | Neosolaniol is a type A trichothecene mycotoxin from Fusarium sp [1]. Neosolaniol evokes robust anorectic response [2]. Uses: Scientific research. Group: Natural products. CAS No. 36519-25-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N6799. | |
| Neostigmine Bromide | Neostigmine (Eustigmin) Bromide is an orally active and reversible cholinesterase inhibitor that acts on myasthenia gravis to prolong and intensify the muscarinic and nicotinic effects of acetylcholine. Neostigmine Bromide can be used in anesthesia to reverse the neuromuscular blockade produced by competitive neuromuscular blockers [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Eustigmin bromide; Neoserine bromide. CAS No. 114-80-7. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B0423. | |
| Neostigmine methyl sulfate | Neostigmine methyl sulfate is a reversible inhibitor of acetylcholinesterase, can not cross the blood-brain barrier. Uses: Scientific research. Group: Signaling pathways. CAS No. 51-60-5. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B1206. | |
| Neotame | Neotame is a derivative of Aspartame (HY-B0361) and is a flavor enhancer and low-caloric, non-nutritive, high-intensity artificial sweetener that is 7000-13,000 times sweeter than sugar. Neotame causes intestinal epithelial cell death at high concentrations. Neotame induces Apoptosis of Caco-2 cells [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 165450-17-9. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-W011053. | |
| Nepafenac | Nepafenac (AHR 9434; AL 6515; Nevanac) is a COX-2 inhibitor and the original drug of Amfenac. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AHR 9434; AL 6515. CAS No. 78281-72-8. Pack Sizes: 10 mM * 1 mL; 25 mg; 100 mg. Product ID: HY-17357. | |
| Nepicastat hydrochloride | Nepicastat hydrochloride (SYN-117 hydrochloride) is a selective, potent, and orally active inhibitor of dopamine-beta-hydroxylase. Nepicastat hydrochloride produces concentration-dependent inhibition of bovine ( IC 50 =8.5 nM) and human ( IC 50 =9 nM) dopamine-beta-hydroxylase. Nepicastat hydrochloride can cross the blood-brain barrier (BBB) [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SYN-117 hydrochloride; RS-25560-197 hydrochloride. CAS No. 170151-24-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13289A. | |
| Nepinalone hydrochloride | Nepinalone hydrochloride, an alchilaminate derivative of β-tetralone and an orally active cough suppressant, possesses a non-opioid antitussive activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 22443-55-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-106873A. | |
| Nepsilon-Acetyl-L-lysine | Nepsilon-Acetyl-L-lysine, an endogenous metabolite , is an R-chain N-acetylated α amino acid [1]. Uses: Scientific research. Group: Natural products. CAS No. 692-04-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-113426. | |
| Nerandomilast | Nerandomilast (BI 1015550) is an orally active inhibitor of PDE4B with an IC 50 value of 7.2 nM. Nerandomilast has good safety and potential applications in inflammation, allergic diseases, pulmonary fibrosis, and chronic obstructive pulmonary disease (COPD) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BI 1015550. CAS No. 1423719-30-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153192. | |
| Neratinib | Neratinib (HKI-272) is an orally available, irreversible, highly selective HER2 and EGFR inhibitor with IC 50 s of 59 nM and 92 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HKI-272. CAS No. 698387-09-6. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-32721. | |
| Neratinib maleate | Neratinib (HKI-272) maleate is an orally available, irreversible, highly selective HER2 and EGFR inhibitor with IC 50 s of 59 nM and 92 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HKI-272 maleate. CAS No. 915942-22-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-32721B. | |
| Neridronate | Neridronate is an aminobisphosphonate, licensed in Italy for the treatment of osteogenesis imperfecta (OI) and Pagets disease of bone (PDB). Neridronate is effective also in other skeletal diseases such as osteoporosis, algodystrophy, hypercalcemia of malignancy, and bone metastases [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 79778-41-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119443. | |
| Nerigliatin | Nerigliatin (PF-04937319) is a orally active glucokinase activator ( GKA ) with EC 50 value of 154.4 μM. Nerigliatin maintains glucose-lowering efficacy. Nerigliatin causes peripheral nerve degeneration. Nerigliatin can be used in type 2 diabetes research. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PF-04937319. CAS No. 1245603-92-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108328. | |
| Nerol | Nerol is a constituent of neroli oil. Nerol Nerol triggers mitochondrial dysfunction and induces apoptosis via elevation of Ca 2+ and ROS. Antifungal activity [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 106-25-2. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-N7063. | |
| Nerolidol | Nerolidol has multiple natural membrane activities, possesses anti-cancer, anti-inflammatory, antibacterial and anti-insect activity. Nerolidol Suppresses parasitic activity, suppresses bloodsucking diseases, bloodworm diseases, and other diseases. Nerolidol can protect the cells from lipid and protein properties, damage to DNA, and protect the cells from damage [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 7212-44-4. Pack Sizes: 10 mM * 1 mL; 5 g; 25 g; 50 g. Product ID: HY-N1944. | |
| Neryl acetate | Neryl acetate is a chemical compound isolated from citrus oils [1]. Uses: Scientific research. Group: Natural products. CAS No. 141-12-8. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-W014983. | |
| Nesiritide | Nesiritide (Brain Natriuretic Peptide-32 human) is an agonist of natriuretic peptide receptors (NPRs), with K d values of 7.3 and 13 pM for NPR-A and NPR-C, respectively. Nesiritide can be used for the research of heart failure [1] [2]. Uses: Scientific research. Group: Peptides. Alternative Names: Brain Natriuretic Peptide-32 human; BNP-32. CAS No. 124584-08-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0003. | |
| NESS 0327 | NESS 0327 is a cannabinoid antagonist with high selectivity for the cannabinoid CB1 receptor. NESS 0327 is more than 60,000-fold selective for the CB1 receptor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 494844-07-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117139. | |
| Netakimab | Netakimab is an anti- IL-17 monoclonal antibody. Nerelimomab can be used for research of ankylosing spondylitis, psoriatic arthritis, moderate-to-severe plaque psoriasis [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1796570-08-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99754. | |
| Netarsudil | Netarsudil is a Rho kinase ( ROCK ) and norepinephrine transporter ( NET ) inhibitor. Netarsudil increases outflow facility in human eyes through multiple mechanisms [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AR-13324. CAS No. 1254032-66-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12798. | |
| Netarsudil dimesylate | Netarsudil mesylate (AR-13324 mesylate) is a small-molecule inhibitor of Rho kinase and a norepinephrine transporter; reduces intraocular pressure (IOP) in normotensive monkey eyes. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AR-13324 dimesylate. CAS No. 1422144-42-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12798A. | |
| Netarsudil hydrochloride | Netarsudil hydrochloride (AR-13324 hydrochloride) is a Rho-associated protein kinas (ROCK) and norepinephrine transporter (NET) inhibitor. Netarsudil hydrochloride has effective in intraocular pressure (IOP) reduction [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AR-13324 hydrochloride. CAS No. 1253952-02-1. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12798B. | |
| N-Ethylglycine | N-Ethylglycine is a Glycine (HY-Y0966) derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 627-01-0. Pack Sizes: 250 mg; 1 g; 5 g; 25 g. Product ID: HY-W141879. | |
| N-Ethyl Hexylone hydrochloride | N-Ethyl Hexylone hydrochloride is a synthetic Cathinone and analogue of methylone and other beta-keto methylenedioxyamphetamines [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 27912-41-0. Pack Sizes: 1 mg. Product ID: HY-129801. | |
| N-Ethylmaleimide | N-Ethylmaleimide (NEM) derives from maleic acid, it can alkylates free sulfhydryl. N-Ethylmaleimide is an irreversible cysteine protease inhibitor. N-ethylmaleimide specific inhibits phosphate transport in mitochondria. N-Ethylmaleimide inhibits prolyl endopeptidase with an IC 50 value of 6.3 μM. N-Ethylmaleimide can be used to modify cysteine residues in proteins and peptides [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: NEM. CAS No. 128-53-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D0843. | |
| N-Ethylmaleimide-d5 | N-Ethylmaleimide-d 5 is the deuterium labeled N-Ethylmaleimide. N-Ethylmaleimide (NEM), a reagent that alkylates free sulfhydryl groups, is a cysteine protease inhibitor[1]. N-ethylmaleimide specific inhibits phosphate transport in mitochondria[2]. N-Ethylmaleimide is also a deubiquitinating enzyme inhibitor[3]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: NEM-d5. CAS No. 360768-37-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-D0843S. | |
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