MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Nicotiflorin | Nicotiflorin is a flavonoid glycoside extracted from a traditional Chinese medicine Carthamus tinctorius. Nicotiflorin shows potent antiglycation activity and neuroprotection effects. Uses: Scientific research. Group: Natural products. CAS No. 17650-84-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-N1475. |  |
| Nicotinamide | Nicotinamide is a form of vitamin B3 or niacin. Nicotinamide Hydrochloride inhibits SIRT2 activity ( IC 50 : 2 μM). Nicotinamide also inhibits SIRT1. Nicotinamide increases cellular NAD + , ATP, ROS levels. Nicotinamide inhibits tumor growth and improves survival. Nicotinamide also has anti- HBV activity [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Niacinamide; Nicotinic acid amide. CAS No. 98-92-0. Pack Sizes: 500 mg; 1 g; 5 g. Product ID: HY-B0150. | |
| Nicotinamide-guanine dinucleotide sodium | Nicotinamide-guanine dinucleotide sodium, a NAD sodium (HY-B0445A) analog, is an oxidized forms of nicotinamide guanine dinucleotide. Nicotinamide-guanine dinucleotide sodium serves as coenzymes for alcohol dehydrogenase (ADH) in vitro [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2600354-60-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-164690A. | |
| Nicotinamide N-oxide | Nicotinamide N-oxide, an in vivo nicotinamide metabolite, is a potent, and selective antagonist of the CXCR2 receptor. Uses: Scientific research. Group: Natural products. CAS No. 1986-81-8. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-101407. | |
| Nicotinamide riboside chloride | Nicotinamide riboside Chloride, an orally active NAD + precursor, increases NAD + levels and activates SIRT1 and SIRT3. Nicotinamide riboside Chloride is a source of vitamin B3 (niacin) and enhances oxidative metabolism, protection against high fat diet-induced metabolic abnormalities [1]. Nicotinamide riboside Chloride reduces cognitive deterioration in a transgenic mouse model of Alzheimers disease [2]. Uses: Scientific research. Group: Natural products. CAS No. 23111-00-4. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-123033A. | |
| Nicotinohydrazide | Nicotinohydrazide (Nicotinic acid hydrazide) is a small molecular compound [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Nicotinic acid hydrazide. CAS No. 553-53-7. Pack Sizes: 10 mM * 1 mL; 10 g; 25 g. Product ID: HY-W012617. | |
| Nicotinuric acid | Nicotinuric acid is an acyl glycine. Nicotinuric acid is a metabolite of nicotinic acid. Uses: Scientific research. Group: Natural products. CAS No. 583-08-4. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-113353. | |
| Nidufexor | Nidufexor (LMB763) is an orally-available farnesoid X receptor ( FXR ) agonist for the research of nonalcoholic steatohepatitis (NASH) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LMB763. CAS No. 1773489-72-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-109096. | |
| Nifedipine | Nifedipine (BAY-a-1040) is a potent calcium channel blocker and agent of choice for cardiac insufficiencies. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY-a-1040. CAS No. 21829-25-4. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B0284. | |
| Nifekalant hydrochloride | Nifekalant hydrochloride (MS-551), a class III antiarrhythmic agent, is a IKr potassium channel blocker with an IC 50 of 10 μM. Nifekalant hydrochloride can be used for refractory ventricular tachyarrhythmias research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MS-551. CAS No. 130656-51-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-B0772A. | |
| Nifenalol hydrochloride | Nifenalol hydrochloride is a β-adrenergic receptor antagonist. Nifenalol hydrochloride induces the Early Afterdepolarization (EAD) effect. EAD is a phenomenon in cardiac electrophysiology that usually occurs during an action potential in ventricular muscle cells and can lead to arrhythmia. The EAD effect of Nifenalol hydrochloride can be blocked by Tetrodotoxin. Nifenalol hydrochloride is used in the study of conditions such as irregular heartbeat or high blood pressure [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 5704-60-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-100952. | |
| Nifenazone | Nifenazone is a pyrazole agent which can be used in the in the treatment of a variety of rheumatic disorders. Uses: Scientific research. Group: Signaling pathways. CAS No. 2139-47-1. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-17475. | |
| Niflumic acid | Niflumic acid is a calcium-activated chloride channel blocker and COX -2 inhibitor with the IC 50 value of 100 nM. Niflumic acid induces apoptosis through caspase-8 / Bid / Bax pathway in lung cancer cells. Niflumic acide exhibits anti-tumor activity by affecting the expression of ERK1/2 and the activity of MMP2 and MMP9. Niflumic acid has orally bioactivity. Niflumic acid acts on rheumatoid arthritis [1] [2] [3] [4] [5] [6] [7] [8]. Uses: Scientific research. Group: Signaling pathways. CAS No. 4394-00-7. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B0493. | |
| Nifuratel | Nifuratel (NF 113) is an orally active broad-spectrum antibiotic with antiprotozoal, antibacterial, anticancer and anti-inflammatory activities, and has good inhibitory effects on Candida and Trichomonas. Nifuratel is also a STAT3 inhibitor, which significantly inhibits the growth and proliferation of human gastric cancer cells and induces apoptosis. In addition, Nifuratel also inhibits mast cell-mediated antigen hypersensitivity reactions and can be used in the study of IgE-mediated allergic diseases [1] [2] [3] [4] [5] [6] [7] [8]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NF 113; SAP 113; Methylmercadone. CAS No. 4936-47-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-A0059. | |
| Nifuroxazide | Nifuroxazide is an effective inhibitor of STAT3 , also exerts potent anti-tumor and anti-metastasis activity. Nifuroxazide is an orally active nitrofuran antibiotic. Uses: Scientific research. Group: Signaling pathways. CAS No. 965-52-6. Pack Sizes: 10 mM * 1 mL; 200 mg; 500 mg. Product ID: HY-B1436. | |
| Nifurtimox | Nifurtimox, an antiprotozoal agent, which is generally used for the treatment of infections with Trypanosoma cruzi , has been used in the therapy of neuroblastoma. Nifurtimox affects enzyme activity of lactate dehydrogenase ( LDH ). Uses: Scientific research. Group: Signaling pathways. CAS No. 23256-30-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W040073. | |
| Nigericin | Nigericin is an antibiotic derived from Streptomyces hygroscopicus that act as a K + /H + ionophore , promoting K + /H + exchange across mitochondrial membranes. Nigericin is a NLRP3 activator. Nigericin shows promising anti-cancer activities through decreasing intracellular pH (pHi), and inactivation of Wnt / β-catenin signals. Nigericin induces pyroptosis through caspase 1 /GSDMD in TNBC [1] [2] [3] [4] [5] [6] [7]. Uses: Scientific research. Group: Signaling pathways. CAS No. 28380-24-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-127019. | |
| Nigericin sodium salt | Nigericin sodium salt is an antibiotic derived from Streptomyces hygroscopicus that act as a K + /H + ionophore , promoting K + /H + exchange across mitochondrial membranes. Nigericin sodium salt is a NLRP3 activator. Nigericin sodium salt shows promising anti-cancer activities through decreasing intracellular pH (pHi), and inactivation of Wnt / β-catenin signals. Nigericin sodium salt induces pyroptosis through caspase 1 /GSDMD in TNBC [1] [2] [3] [4] [5] [6] [7]. Uses: Scientific research. Group: Natural products. CAS No. 28643-80-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100381. | |
| (+)-Niguldipine hydrochloride | (+)-Niguldipine hydrochloride is an antagonist for calcium channel. (+)-Niguldipine hydrochloride produces vasodilation by blocking calcium channels and reducing the transmembrane influx of calcium ions. (+)-Niguldipine hydrochloride inhibits U-46619 (HY-108566)-induced coronary vasoconstriction in guinea pig Langendorff heart with pID 50 of 11.37, binds to calcium channel on guinea pig skeletal muscle membrane with K i of 9.75, and lowers the blood pressure in spontaneously hypertensive rat with pED 30 of 7.1. (+)-Niguldipine hydrochloride ameliorates cardiovascular diseases such as hypertension, angina pectoris and arrhythmias [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (S)-Niguldipine hydrochloride. CAS No. 113145-69-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-101390. | |
| Nikethamide | Nikethamide (N,N-Diethylnicotinamide), one of the respiratory central stimulants, has the potential for respiratory failure research [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: N,N-Diethylnicotinamide. CAS No. 59-26-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-B1280. | |
| Nikkomycin Z | Nikkomycin Z is a nucleoside peptide and an orally active antifungal agent. Nikkomycin Z inhibits chitin synthesis by acting as a competitive analogue of the chitin synthase substrate UDP-N-acetylglucosamine. Nikkomycin Z has antifungal activity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 59456-70-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-19593. | |
| Nile blue chloride | Nile blue chloride is a highly fluorescent and photostable organic dye. Nile blue chloride and fluorescein isothiocyanate (FITC) can be used to construct a ratiometric pH sensitive probe for tracking the pH of the extracellular fluid between cancer cells in realtime. Nile Blue chloride has the potential for the research of nonlinear optics [1] [2]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 2381-85-3. Pack Sizes: 1 g. Product ID: HY-W110898. | |
| Nile Red | Nile red (Nile blue oxazone) is a lipophilic stain. Nile red has environment-sensitive fluorescence. Nile red is intensely fluorescent in a lipid-rich environment while it has minimal fluorescence in aqueous media. Nile red is an excellent vital stain for the detection of intracellular lipid droplets by fluorescence microscopy and flow cytof uorometry. Nile red stains intracellular lipid droplets red. The fluorescence wavelength is 559/635 nm [1]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Nile Blue A oxazone; Phenoxazone 9. CAS No. 7385-67-3. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-D0718. | |
| Nilotinib | Nilotinib is an orally available Bcr-Abl tyrosine kinase inhibitor with antineoplastic activity. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AMN107. CAS No. 641571-10-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg. Product ID: HY-10159. | |
| Nilutamide | Nilutamide (Nilandron) is an orally active nonsteroidal androgen receptor antagonist with affinity for androgen receptors but not for progestogen, estrogen or glucocorticoid receptors. Nilutamide can be used to research prostate cancer. Nilutamide also has antischistosomal properties [1] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Nilandron; RU 23908. CAS No. 63612-50-0. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-13702. | |
| Nilvadipine | Nilvadipine is a potent calcium channel antagonist, and the IC 50 value is around 0.1 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FK235; FR34235. CAS No. 75530-68-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-14284. | |
| Nimbin | Nimbin is a intermediate limonoid isolated from Azadirachta. Nimbin prevents tau aggregation and increases cell viability. Nimbin is effective inhibits the envelope protein of dengue virus. Nimbin has anti-inflammatory, antipyretic, antifungal, antihistamine, antiseptic, antioxidant, anti-cancer and anti-viral properties. Nimbin can across blood-brain barrier [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 5945-86-8. Pack Sizes: 1 mg. Product ID: HY-N3187. | |
| Nimesulide | Nimesulide is a selective COX-2 inhibitor, with IC 50 s of 70 nM-70 μM in a time-dependent manner, but it shows no effect on COX-1 (IC 50 >100 μM). Nimesulide has potent anti-inflammatory, analgesic and antipyretic properties. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R805. CAS No. 51803-78-2. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0363. | |
| Nimodipine | Nimodipine (BAY-e 9736) is an orally active, well-tolerated and light-sensitive dihydropyridine calcium antagonist. Nimodipine can be used for the research of cerebrovascular disorders [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY-e 9736. CAS No. 66085-59-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-B0265. | |
| Nimorazole | Nimorazole (K-1900), a 2-nitroimidazole, is a hypoxic cell-radiation sensitizer. Nimorazole has anti-infective and anti-protozoal against trichomoniasis. Nimorazole has the potential for head and neck cancer [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: K-1900. CAS No. 6506-37-2. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-16349. | |
| Nimotuzumab | Nimotuzumab is a humanized IgG1 monoclonal antibody targeting EGFR with a K D of 0.21 nM. Nimotuzumab is directed against the extracellular domain of the EGFR blocking the binding to its ligands. Nimotuzumab, a strong antitumor agent, is cytolytic on target tumors by its capacity to cause antibody dependent cell mediated cytotoxicity (ADCC) and complement dependent cytotoxicity (CDC) [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 780758-10-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P9968. | |
| Nimustine hydrochloride | Nimustine hydrochloride (ACNU) is a DNA cross-linking and DNA alkylating agent, which induces DNA replication blocking lesions and DNA double-strand breaks and inhibits DNA synthesis , commonly used in chemotherapy for glioblastomas [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ACNU. CAS No. 55661-38-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13703A. | |
| Ninerafaxstat | Ninerafaxstat (IMB-1018972) is a novel orally active cardiac mitochondrial drug that restores myocardial energy homeostasis. Ninerafaxstat competitively inhibits 3-ketoacyl-CoA thiolase (3-KAT) to partially suppress fatty acid oxidation, and shifts cardiac energy metabolism from free fatty acid oxidation to glucose oxidation, regulating myocardial substrate utilization and thereby improving cardiac efficiency. Ninerafaxstat can be used for research on cardiovascular diseases [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IMB-1018972; IMB-101. CAS No. 2254741-41-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139577. | |
| Ningetinib | Ningetinib is a potent, orally bioavailable small molecule tyrosine kinase inhibitor ( TKI ) with IC 50 s of 6.7, 1.9 and <1.0 nM for c-Met , VEGFR2 and Axl , respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1394820-69-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107145A. | |
| Ningetinib Tosylate | Ningetinib Tosylate is a potent, orally bioavailable small molecule tyrosine kinase inhibitor ( TKI ) with IC 50 s of 6.7, 1.9 and <1.0 nM for c-Met , VEGFR2 and Axl , respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1394820-77-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-107145. | |
| Ninhydrin | Ninhydrin can be used as a chromogenic analytical probe for the quantification of amino acids and proteins. Uses: Scientific research. Group: Fluorescent dye. CAS No. 485-47-2. Pack Sizes: 10 mM * 1 mL; 25 g; 50 g; 100 g. Product ID: HY-D0908. | |
| Nintedanib | Nintedanib (BIBF 1120) is a potent triple angiokinase inhibitor for VEGFR1/2/3 , FGFR1/2/3 and PDGFRα/β with IC 50 s of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BIBF 1120. CAS No. 656247-17-5. Pack Sizes: 10 mM * 1 mL; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-50904. | |
| Nintedanib esylate | Nintedanib esylate (BIBF 1120 esylate) is a potent triple angiokinase inhibitor for VEGFR1/2/3 , FGFR1/2/3 and PDGFRα/β with IC 50 s of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BIBF 1120 esylate. CAS No. 656247-18-6. Pack Sizes: 10 mM * 1 mL; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-11106. | |
| N-Iodosuccinimide | N-Iodosuccinimide is a biological material or organic compound that can be used in life science research [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 516-12-1. Pack Sizes: 50 g; 100 g; 500 g. Product ID: HY-ER017. | |
| Nipecotic acid | Nipecotic acid ((±)-β-Homoproline) is a potent inhibitor of neuronal and glial-aminobutyric acid ( GABA ) uptake in vitro. Nipecotic acid can also directly activate GABA A -like chloride channels , with an EC 50 of approximately 300 μM [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (±)-β-Homoproline; Hexahydronicotinic acid; 3-Carboxypiperidine. CAS No. 498-95-3. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-69359. | |
| Niperotidine | Niperotidine is a histamine H2-receptor antagonist. Uses: Scientific research. Group: Signaling pathways. CAS No. 84845-75-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15539. | |
| Nipocalimab | Nipocalimab (M281) is a fully human, recombinant, aglycosylated IgG1 monoclonal antibody. Nipocalimab is a human deglycosylated IgG1 anti-FcRn monoclonal antibody that binds with picomolar affinity to Fc receptor ( FcRn ) at both endosomal pH 6.0 and extracellular pH 7.6 [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: M281. CAS No. 2211985-36-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99037. | |
| Niraparib | Niraparib (MK-4827) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with IC 50 s of 3.8 and 2.1 nM, respectively. Niraparib leads to inhibition of repair of DNA damage, activates apoptosis and shows anti-tumor activity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-4827. CAS No. 1038915-60-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-10619. | |
| Niraparib hydrochloride | Niraparib hydrochloride (MK-4827 hydrochloride) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with IC 50 s of 3.8 and 2.1 nM, respectively. Niraparib hydrochloride leads to inhibition of repair of DNA damage, activates apoptosis and shows anti-tumor activity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-4827 hydrochloride. CAS No. 1038915-64-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10619A. | |
| Niraparib tosylate | Niraparib tosylate (MK-4827 tosylate) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with an IC 50 of 3.8 and 2.1 nM, respectively. Niraparib tosylate leads to inhibition of repair of DNA damage, activates apoptosis and shows anti-tumor activity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-4827 tosylate. CAS No. 1038915-73-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10619B. | |
| Niraparib tosylate hydrate | Niraparib (MK-4827) tosylate hydrate is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with IC 50 s of 3.8 and 2.1 nM, respectively. Niraparib tosylate hydrate leads to inhibition of repair of DNA damage, activates apoptosis and shows anti-tumor activity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-4827 tosylate hydrate. CAS No. 1613220-15-7. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10619E. | |
| Niraxostat | Niraxostat (Y-700; Piraxostat) is an orally active xanthine oxidoreductase ( XOR ) inhibitor used in the study of hyperuricemia and other diseases in which XOR may be involved [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Y-700; Piraxostat. CAS No. 206884-98-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-14669. | |
| Niridazole | Niridazole is an anaerobic and microaerophilic bacterial inhibitor with IC 50 values ranging from 0.0037 to 1.0 μg/mL [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BA-32644. CAS No. 61-57-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-119614. | |
| Nirmatrelvir | Nirmatrelvir (PF-07321332) is a potent and orally active SARS-CoV 3C-like protease (3CL PRO ) inhibitor. Nirmatrelvir (PF-07321332) targets to the SARS-CoV-2 virus and can be used for COVID-19 research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PF-07321332. CAS No. 2628280-40-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-138687. | |
| Nirogacestat | Nirogacestat (PF-3084014) is a reversible, orally bioavailable, noncompetitive, and selective γ-secretase inhibitor with an IC 50 of 6.2 nM. Inhibition of Notch signaling by Nirogacestat while minimizing gastrointestinal toxicity presents a promising approach for research of Notch receptor-dependent cancers [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PF-3084014. CAS No. 1290543-63-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15185. | |
| Nirsevimab | Nirsevimab (MEDI8897) is a recombinant monoclonal antibody against human respiratory syncytial virus ( RSV ). Nirsevimab has neutralizing activity against RSV A and RSV B viruses, with IC 50 values of 5.42 ng/mL and 9.71 ng/mL, respectively. Nirsevimab can be used for research on respiratory infections [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MEDI8897. CAS No. 1989556-22-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99756. | |
| Nirvanol | Nirvanol (Ethylphenylhydantoin) is a metabolite of Mephenytoin (HY-B1184) that exerts anticonvulsant effects in the Maximal Electroshock (M.E.S.) seizure model in mice. The ED 50 of Nirvanol is 23 mg/kg (measured 30 minutes after intraperitoneal injection) and 30 mg/kg (measured 2 hours after intraperitoneal injection). Nirvanol shows potential for research in epilepsy-related neurological disorders [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ethylphenylhydantoin; Phenylethyihydantoin; Desmethylmephenytoin. CAS No. 631-07-2. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-W012481. | |
| Nisevokitug | Nisevokitug (NIS-793) is a human, IgG2λ antibody targeting TGF-β ( TGFB1/TGFB2 ). Nisevokitug is expressed by CHO-K1 cells [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: NIS-793. CAS No. 2649854-92-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990009. | |
| Nisin | Nisin is a bacteriocin produced by a group of Gram-positive bacteria that belongs to Lactococcus and Streptococcus species. Nisin has antibacterial and anti-inflammatory activity [1] [2] [3]. Uses: Scientific research. Group: Peptides. CAS No. 1414-45-5. Pack Sizes: 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-P1607. | |
| N-Isobutyrylglycine-d2 | N-Isobutyrylglycine-d 2 is the deuterium labeled N-Isobutyrylglycine[1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 1219795-05-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-W141928S1. | |
| Nisoldipine | Nisoldipine (BAY-k 5552; Sular) is an orally active and blood-brain barrier-penetrating dihydropyridine calcium antagonist, with greater vascular selectivity than other calcium channel antagonists. Nisoldipine inhibits calcium influx and blocks voltage-gated calcium channels. Nisoldipine dilates coronary and systemic arteries. Nisoldipine has antihypertensive and anti-anginal activity. Nisoldipine also displays neuroprotective and antiviral activity [1] [2] [7] [11]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY-k 5552. CAS No. 63675-72-9. Pack Sizes: 100 mg; 500 mg; 1 g. Product ID: HY-17402. | |
| N-Isopropyl-N'-phenyl-p-phenylenediamine | N-Isopropyl-N'-phenyl-p-phenylenediamine is an antioxidant used in rubber manufacturing to reduce the detrimental effect of oxygen. N-Isopropyl-N'-phenyl-p-phenylenediamine can cause contact allergy [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 101-72-4. Pack Sizes: 10 mM * 1 mL; 100 g. Product ID: HY-W130442. | |
| N-Isovaleroylglycine | N-Isovaleroylglycine is an acyl glycine and could be used as a biomarker for the predispositon for weight gain and obesity. Uses: Scientific research. Group: Natural products. CAS No. 16284-60-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-W015464. | |
| Nisoxetine | Nisoxetine is a potent and selective inhibitor of noradrenaline transporter (NET) , with a K d of 0.76 nM. Nisoxetine is an antidepressant and local anesthetic, it can block voltage-gated sodium channels [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 53179-07-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1704. | |
| Nisoxetine hydrochloride | Nisoxetine hydrochloride is a potent and selective inhibitor of noradrenaline transporter (NET) , with a K d of 0.76 nM. Nisoxetine hydrochloride is an antidepressant and local anesthetic, it can block voltage-gated sodium channels [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 57754-86-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1704A. | |
| Nitazoxanide | Nitazoxanide (NTZ), an anthelmintic agent, exhibits a broad spectrum of activities against a wide variety of helminths, protozoa, and enteric bacteria infecting animals and humans. Nitazoxanide inhibits Giardia lamblia trophozoite proliferation in axenic culture with an IC 50 of 2.4 μM [1]. Nitazoxanide can be used for the research of parasitic gastroenteritis. Nitazoxanide shows anti-Japanese encephalitis virus (JEV) activity in a mouse model [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NTZ; NSC 697855. CAS No. 55981-09-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-B0217. | |
| NITD008 | NITD008 is a potent and selective flaviviruse inhibitor which can inhibit Dengue Virus Type 2 (DENV-2) with an EC 50 of 0.64 μM. NITD008 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 7-Deaza-2'-C-acetylene-adenosine. CAS No. 1044589-82-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-12957. | |
| Nitecapone | Nitecapone (OR-462) is an orally active and short-acting catechol-O-methyltransferase (COMT) inhibitor with gastroprotective and antioxidant properties. Nitecapone (OR-462) scavenges reactive oxygen and nitric radicals and prevents lipid peroxidation [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: OR-462. CAS No. 116313-94-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-106842. | |
| Nitenpyram | Nitenpyram is a calss of neonicotinoid and an insect nicotinic acetylcholine receptor (nAChR) agonist with an IC 50 of 14 nM. Nitenpyram is an oral fast-acting insecticide used to suppress sucking insects on companion animals [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 150824-47-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg; 500 mg. Product ID: HY-B0820. | |
| Nitidine chloride | Nitidine chloride, a potential anti-malarial lead compound derived from Zanthoxylum nitidum (Roxb) DC, exerts potent anticancer activity through diverse pathways, including inducing apoptosis , inhibiting STAT3 signaling cascade, DNA topoisomerase 1 and 2A , ERK and c-Src/FAK associated signaling pathway, also has anti-inflammatory activity. Nitidine chloride inhibits LPS-induced inflammatory cytokines production via MAPK and NF-kB pathway [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. CAS No. 13063-04-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N0498. | |
| Nitisinone | Nitisinone is an orally active, competitive and reversible 4-hydroxyphenylpyruvate dioxygenase ( 4-HPPD ) inhibitor with an IC 50 of 173 nM. Nitisinone promotes tyrosine accumulation in a dose-dependent manner. nitisinone can be used in studies of hereditary tyrosinemia type 1 (HT-1) (a rare genetic disorder) and albinism [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NTBC; Nitisone; SC0735. CAS No. 104206-65-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0607. | |
| Nitrendipine | Nitrendipine (BAY-E-5009), an analogue of Nifedipine (HY-B0284), is a dihydropyridine calcium channel blocker with vasodilator action. Nitrendipine has antihypertensive effect [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY-E-5009. CAS No. 39562-70-4. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-B0424. | |
| Nitrilotriacetic acid | Nitrilotriacetic acid is an aminotricarboxylic acid. Nitrilotriacetic acid can be used as a chelating agent, forming coordination compounds with metal ions [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Triglycollamic acid. CAS No. 139-13-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-W030778. | |
| Nitro blue tetrazolium chloride | Nitro blue tetrazolium chloride (NBT) is a substrate for dehydrogenases; is used with the alkaline phosphatase substrate 5-Bromo-4-Chloro-3-Indolyl Phosphate (BCIP) in western blotting and immunohistological staining procedures [1]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: NBT. CAS No. 298-83-9. Pack Sizes: 10 mM * 1 mL; 250 mg; 500 mg. Product ID: HY-15925. | |
| Nitrofen | Nitrofen is a selective contact herbicide. Nitrofen is a retinal dehydrogenase (belongs to the ALDH family) and protoporphyrinogen oxidase inhibitor [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1836-75-5. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B1877. | |
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