MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Norstictic acid | Norstictic acid is a potent and selective allossteric transcriptional regulator. Norstictic acid shows anticancer activity. Norstictic acid shows antioxidant activity and antimicrobial activity [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 571-67-5. Pack Sizes: 1 mg. Product ID: HY-N10457. |  |
| Nortanshinone | Nortanshinone is a pigment isolated from Dan-Shen [1]. Uses: Scientific research. Group: Natural products. CAS No. 97399-70-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N6914. | |
| Nortrachelogenin | Nortrachelogenin ((-)-Wikstromol) from Partrinia scabiosaefolia elicits an apoptotic response in Candida albicans [1]. Uses: Scientific research. Group: Natural products. Alternative Names: (-)-Wikstromol; (-)-Nortrachelogenin. CAS No. 34444-37-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N3171. | |
| (+)-Nortrachelogenin | (+)-Nortrachelogenin (Wikstromol), a pharmacologically ligand from from wikstroemia indica , possesses antileukemic activity [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Wikstromol. CAS No. 61521-74-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N3171A. | |
| Nortriptyline | Nortriptyline (Desmethylamitriptyline), the main active metabolite of Amitriptyline, is a tricyclic antidepressant. Nortriptyline is a potent autophagy inhibitor and has anticancer effects [1] [2] [3]. N. Uses: Scientific research. Group: Natural products. Alternative Names: Desmethylamitriptyline; Desitriptilina. CAS No. 72-69-5. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-118620. | |
| Nortriptyline-d3 hydrochloride | Nortriptyline-d 3 (hydrochloride) is the deuterium labeled Nortriptyline hydrochloride. Nortriptyline hydrochloride (Desmethylamitriptyline hydrochloride) is a tricyclic antidepressant and the main active metabolite of Amitriptyline, and used to relieve the symptoms of depression[1]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: Desmethylamitriptyline-d3 (hydrochloride); Desitriptilina-d3 (hydrochloride). CAS No. 203784-52-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-B1417S. | |
| Nortriptyline hydrochloride | Nortriptyline (Desmethylamitriptyline) hydrochloride, the main active metabolite of Amitriptyline, is a tricyclic antidepressant. Nortriptyline hydrochloride is a potent autophagy inhibitor and has anticancer effects [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Desmethylamitriptyline hydrochloride; Desitriptilina hydrochloride. CAS No. 894-71-3. Pack Sizes: 10 mM * 1 mL; 50 mg. Product ID: HY-B1417. | |
| Nortropine | Nortropine (Nortropenol), isolated from the total alkaloids of Convolvulus subhirsutus , is an intermediate in tropine breakdown and reactions leading to succinate [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Nortropenol. CAS No. 538-09-0. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-W018601. | |
| Nortropine hydrochloride | Nortropine hydrochloride can be isolated from the Convolvulus subhirsutus alkaloid and is an intermediate in the decomposition and reaction of tropine to produce succinic acid [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Nortropenol hydrochloride. CAS No. 14383-51-8. Pack Sizes: 10 mM * 1 mL; 1 g. Product ID: HY-W066915. | |
| Nortropinone hydrochloride | Nortropinone hydrochloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 25602-68-0. Pack Sizes: 25 g. Product ID: HY-76030. | |
| Norverapamil hydrochloride | Norverapamil hydrochloride ((±)-Norverapamil hydrochloride), an N-demethylated metabolite of Verapamil, is a L-type calcium channel blocker and a P-glycoprotein (P-gp) function inhibitor [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (±)-Norverapamil hydrochloride; D591 hydrochloride. CAS No. 67812-42-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-100750. | |
| Noscapine | Noscapine ((S,R)-Noscapine) is an orally active phthalideisoquinoline alkaloid with potent antitussive. Noscapine exerts its antitussive effects by activating sigma opioid receptors and is a non-competitive Bradykinin inhibitor. Noscapine disrupts microtubule dynamics, induces mitotic arrest and apoptosis. Noscapine possesses anticancer, neuroprotective, anti-inflammatory activities, and can cross the blood-brain barrier [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. Alternative Names: (S,R)-Noscapine. CAS No. 128-62-1. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-13716. | |
| Noscapine hydrochloride | Noscapine ((S,R)-Noscapine) hydrochloride is an orally active phthalideisoquinoline alkaloid with potent antitussive. Noscapine hydrochloride exerts its antitussive effects by activating sigma opioid receptors and is a non-competitive Bradykinin inhibitor. Noscapine hydrochloride disrupts microtubule dynamics, induces mitotic arrest and apoptosis. Noscapine hydrochloride possesses anticancer, neuroprotective, anti-inflammatory activities, and can crosse the blood-brain barrier [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (S,R)-Noscapine hydrochloride. CAS No. 912-60-7. Pack Sizes: 100 mg. Product ID: HY-13716A. | |
| Nosiheptide | Nosiheptide (Multhiomycin), a thiopeptide antibiotic produced by Streptomyces actuosus , inhibits bacterial protein synthesis and bears a unique indole side ring system and regiospecific hydroxyl groups on the characteristic macrocyclic core. Nosiheptide has been widely used as a feed additive for animal growth [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Multhiomycin; RP 9671. CAS No. 56377-79-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-107486. | |
| NOTA | NOTA is a bifunctional chelate which acts as the framework to construct PET imaging tools. NOTA also can be used for probe design and signal amplification via the multivalent effect. NOTA can be used in multiple myeloma, breast cancer, lymphoma and myocardial infarction research [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. CAS No. 56491-86-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134418. | |
| Notoginsenoside R1 | Notoginsenoside R1 (Sanchinoside R1), a saponin, is isolated from P. notoginseng. Notoginsenoside R1 exhibits anti-oxidation, anti-inflammatory, anti-angiogenic, and anti-apoptosis activities. Notoginsenoside R1 provides cardioprotection against ischemia/reperfusion (I/R) injury. Notoginsenoside R1 also provides neuroprotection in H 2 O 2 -induced oxidative damage in PC12 cells [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Sanchinoside R1; Sanqi glucoside R1. CAS No. 80418-24-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0615. | |
| Notoginsenoside R4 | Notoginsenoside R4 is a ginsenoside that can be isolated from ginseng roots. In the molecular docking results, Notoginsenoside R4 can target STAT3, AKT1, HRAS, VEGFA and CASP3 [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 87741-77-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N10336. | |
| Notoginsenoside S | Notoginsenoside S is a compound isolated from Panax notoginseng. Uses: Scientific research. Group: Natural products. CAS No. 575446-95-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N5019. | |
| Notopterol | Notopterol is a coumarin extracted from N. incisum. Notopterol induces apoptosis and has antipyretic, analgesic and anti-inflammatory effects. Notopterol is used for acute myeloid leukemia (AML) [1]. Uses: Scientific research. Group: Natural products. CAS No. 88206-46-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-N0564. | |
| Nourseothricin sulfate | Nourseothricin sulfate (Streptothricin sulfate) is a broad-spectrum antibiotic that destroys the outer membrane of Gram-negative bacteria and is a dominant selective marker for Fonsecaea pedrosoi [1] [2]. Nourseothricin sulfate inhibits protein biosynthesis in prokaryotic cells and strongly inhibits the growth of eukaryotes like fungi and can also be used as a elective marker for a wide range of organisms including bacteria , yeast, filamentous fungi , and plant cells [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Streptothricin sulfate. CAS No. 96736-11-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-129065. | |
| Novaluron | Novaluron is a chemical with insecticide properties, an insect growth regulator, and has adverse effects on mouse sperm [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 116714-46-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg. Product ID: HY-17519. | |
| Novobiocin | Novobiocin (Albamycin) is a potent and orally active antibiotic. Novobiocin also is a DNA gyrase inhibitor and a heat shock protein 90 (Hsp90) antagonist. Novobiocin has the potential for the research of highly beta-lactam-resistant pneumococcal infections. Novobiocin shows anti-orthopoxvirus activity [1] [2] [3] [4] [6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Albamycin; Cathomycin. CAS No. 303-81-1. Pack Sizes: 5 mg. Product ID: HY-B0425. | |
| Novobiocin sodium | Novobiocin (Albamycin) sodium is a potent and orally active antibiotic. Novobiocin sodium also is a DNA gyrase inhibitor and a heat shock protein 90 (Hsp90) antagonist. Novobiocin sodium has the potential for the research of highly beta-lactam-resistant pneumococcal infections. Novobiocin sodium shows anti-orthopoxvirus activity [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Albamycin sodium; Cathomycin sodium. CAS No. 1476-53-5. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0425A. | |
| Noxa A BH3 | Noxa A BH3 is a biological active peptide. (BH3 domain of Noxa protein). Uses: Scientific research. Group: Peptides. CAS No. 505070-09-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P5328. | |
| NP-1815-PX sodium | NP-1815-PX sodium is a potent and selective P2X4R antagonist. NP-1815-PX sodium has anti-inflammatory activity, and can relieve pain in chronic pain models. NP-1815-PX sodium also inhibits guinea pig tracheal/bronchial smooth muscle (TSM and BSM) contractions [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1239578-80-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-150270A. | |
| N-Palmitoyl Taurine | Several different arachidonoyl amino acids, including N-arachidonoyl dopamine (NADA) and N-arachidonoyl serine (ARA-S), have been isolated and characterized from bovine brain.1 During mass spectral lipidomic analysis of rat brain, a series of fatty acyl amides of a third amino acid, taurine, is discovered. N-Palmitoyl taurine is a prominent amino-acyl endocannabinoid isolated from rat brain during lipidomics profiling. Its function is currently under investigation. Uses: Scientific research. Group: Signaling pathways. CAS No. 83982-06-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120965. | |
| NPB | NPB is a specific and potent inhibitor of BAD phosphorylation at Ser99 , with an IC 50 of 0.41 μM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2247491-97-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119368. | |
| NPBA | NPBA, a potassium K2P channel TASK-3 (KCNK9) agonist, is a tandem pore domain weak inward rectifying K + channel (TWIK2) channel blocker. NPBA suppresses NLRP3 inflammasome activation in macrophages [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 524033-40-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139064. | |
| NP-G2-044 | NP-G2-044 is a potent, orally active fascin inhibitor, with an IC 50 of ~2 μM. NP-G2-044 blocks tumor metastasis and increases antitumor immune response [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1807454-59-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125506. | |
| N-Phenethylbenzamide | N-Phenethylbenzamide is an active compound. N-Phenethylbenzamide can be extracted from Liriodendron tulipifera. N-Phenethylbenzamide can be used for the research of inflammatory diseases [1]. Uses: Scientific research. Group: Natural products. CAS No. 3278-14-6. Pack Sizes: 10 mM * 1 mL; 1 g. Product ID: HY-32135. | |
| N-Phenylacrylamide | N-Phenylacrylamide is a special polymer showing high affinity with Ochratoxin A, a colorless and crystalline mycotoxin compound. N-Phenylacrylamide can be applied in the field of mycotoxin extraction, and be used for the security research of agricultural commodities and foods made from cereals and grapes [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2210-24-4. Pack Sizes: 10 mM * 1 mL; 1 g. Product ID: HY-W018582. | |
| N-Phenylnaphthalen-1-amine | N-Phenylnaphthalen-1-amine is a fluorescence probe for odorant-binding proteins (OBP) with a dissociation constant of 1.67 μM. N-Phenylnaphthalen-1-amine exhibits an excitation wavelength of 337 nM and an emission wavelength of 407 nM [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 90-30-2. Pack Sizes: 10 mM * 1 mL; 25 g. Product ID: HY-W009756. | |
| NPPB | NPPB is a blocker of the outwardly rectifying chloride channel ( ORCC ). Uses: Scientific research. Group: Signaling pathways. CAS No. 107254-86-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-101012. | |
| NPS-2143 | NPS-2143 (SB-262470A), an orally active calcilytic agent, is a selective and potent calcium ion-sensing receptor (CaSR) antagonist. NPS-2143 (SB-262470A) blocks increases in cytoplasmic Ca 2+ concentrations ( IC 50 =43 nM) elicited by activating the Ca 2+ receptor in HEK 293 cells expressing the human Ca 2+ receptor [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SB-262470A. CAS No. 284035-33-2. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10007. | |
| NPS-2143 hydrochloride | NPS-2143 hydrochloride (SB-262470A hydrochloride), an orally active calcilytic agent, is a selective and potent calcium ion-sensing receptor (CaSR) antagonist. NPS-2143 hydrochloride (SB-262470A hydrochloride) blocks increases in cytoplasmic Ca 2+ concentrations ( IC 50 =43 nM) elicited by activating the Ca 2+ receptor in HEK 293 cells expressing the human Ca 2+ receptor [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SB-262470A hydrochloride. CAS No. 324523-20-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-10171. | |
| NPS 2390 | NPS 2390 is a noncompetitive antagonist of mGluR1 and mGluR5 [1]. NPS 2390 is also a potent CaSR (calcium-sensing receptor) inhibitor [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 226878-01-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-11095. | |
| NQ301 | NQ301 is an antithrombotic agent; inhibits collagen-challenged rabbit platelet aggregation with an IC 50 of 10 mg/mL. Uses: Scientific research. Group: Signaling pathways. CAS No. 130089-98-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101054. | |
| NQO1 substrate | NQO1 substrate acts as an efficient NQO1 substrate and may be a new option for the treatment of NQO1-overexpresssing drug-resistant NSCLC [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2304503-05-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-114315. | |
| Nrf2 activator-1 | Nrf2 activator-1 is a potent activator of NF-E2 related factor 2 ( Nrf2 ). Nrf2 activator-1 has the potential for the research of COPD and other respiratory diseases, including asthma, Acute Lung Injury (ALI), Acute Respiratory Distress Syndrome (ARDS) and pulmonary fibrosis (extracted from patent WO2018109647A1) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2230697-41-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145390. | |
| Nrf2 activator-12 | Nrf2 activator-12 (compund 10v) potently activates Nrf2 (EC50=83.5 nM) and exhibits promising pharmacological properties, reversing disease progression and alleviating demyelination in an experimental autoimmune encephalomyelitis mouse model [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3020661-05-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-169201. | |
| Nrf2-Activator-12G | Nrf2-Activator-12G (compd 12g) is an activator of Nrf2. Nrf2-Activator-12G induces the expression of nrf2-dependentantioxidant enzymes at both mRNA and protein levels in DAergic neuronal cell. Nrf2-Activator-12G can used in study Parkinsons Disease [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1554271-18-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-115849. | |
| Nrf2-IN-3 | Nrf2-IN-3 (Compound R16) is a small-molecule NRF2 inhibitor and increases reactive oxygen species (ROS) production. Nrf2-IN-3 selectively binds KEAP1 mutants and restores their NRF2-inhibitory function by repairing the disrupted KEAP1/NRF2 interactions, leading to proteasome-dependent NRF2 degradation in cells. Nrf2-IN-3 sensitizes KEAP1-mutated tumor cells to Cisplatin (HY-17394), Gefitinib (HY-50895), and KEAP1 G333C-mutated xenograft to Cisplatin [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 6325-13-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-149508. | |
| NRP1 antagonist 1 | NRP1 antagonist 1 (compound 12a) is a potent NRP1 antagonist with an IC 50 of 19.1 μM. NRP1 antagonist 1 has the potential for cancer research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2569598-01-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-133034. | |
| NS 11021 | NS 11021 is a potent and specific Ca 2+ -activated big-conductance K + Channels (KCa1.1 channels) activator. NS 11021 at concentrations above 0.3 μM activates KCa1.1 in a concentration-dependent manner by parallelshifting the channel activation curves to more negative potentials [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 956014-19-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13103. | |
| NS-1619 | NS-1619 is an opener of large conductance Ca 2+ -activated K + (BK) channel. NS-1619 is a highly effective relaxant with an EC 50 of about 10 - 30 μM in several smooth muscles of blood vessels and other tissues [1]. NS1619 inhibits proliferation and induces apoptosis in A2780 ovarian cancer cells [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 153587-01-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-12496. | |
| NS1643 | NS1643 is a partial agonist of human ether-a-go-go-related gene ( hERG ) K + channels with an EC 50 of 10.5 μM. NS1643 inhibits the growth of breast cancer tumors in TNBC mouse models. NS1643 inhibits cell migration and invasion of breast cancer cells [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 448895-37-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16916. | |
| NS383 | NS383 is a potent and uniquely selective inhibitor of rat ASICs containing 1a and/or 3 subunits. NS383 inhibits H(+)-activated currents recorded from rat homomeric ASIC1a, ASIC3, and heteromeric ASIC1a+3 with IC 50 values ranging from 0.61 to 2.2 μM. NS383 is well tolerated and capable of reversing pathological painlike behaviors, presumably via peripheral actions, but possibly also via actions within central pain circuits [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 309711-59-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-131879. | |
| NS3861 | NS3861 is an agonist of nicotinic acetylcholine receptors ( nAChRs ) and binds with high affinity to heteromeric α3β4 nAChR. The binding K i values of 0.62, 25, 7.8, 55 nM for α3β4, α3β2, α4β4, α4β2, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 216853-59-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110121A. | |
| NS3861 fumarate | NS3861 fumarate is an agonist of nicotinic acetylcholine receptors ( nAChRs ) and binds with high affinity to heteromeric α3β4 nAChR. The binding K i values of 0.62, 25, 7.8, 55 nM for α3β4, α3β2, α4β4, α4β2, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 216853-60-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110121. | |
| NS-398 | NS-398 is a non-steroidal an-inflammatory agent with analgesic and antipyretic effects, and selectively inhibits prostaglandin G/H synthase 2/cyclooxygenase 2 ( COX-2 ) activity, with an IC 50 of 3.8 μM, and has no effect on COX-1 at 100 μM. Uses: Scientific research. Group: Signaling pathways. CAS No. 123653-11-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13913. | |
| NS8593 hydrochloride | NS8593 hydrochloride is a potent and selective small conductance Ca 2+ -activated K + channels (SK channels) inhibitor. NS8593 hydrochloride reversibly inhibits SK3 -mediated currents with a K d value of 77 nM. NS8593 hydrochloride inhibits all the SK1-3 subtypes Ca 2+ -dependently ( K d s of 0.42, 0.60, and 0.73 μM, respectively, at 0.5 μM Ca 2+ ), and does not affect the Ca 2+ -activated K + channels of intermediate and large conductance (hIK and hBK channels, respectively) [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 875755-24-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-110105. | |
| NSAH | NSAH is a reversible and competitive nonnucleoside ribonucleotide reductase (RR) inhibitor, with cell-free IC 50 of 32 μM and cell-based IC 50 of ~250 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1099592-35-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114503. | |
| N-Salicyloyltryptamine | N-Salicyloyltryptamine acts on voltage-dependent Na + , Ca 2+ , and K + ion channels inhibitor. N-Salicyloyltryptamine inhibits K + currents with an IC 50 value of 34.6 μM ( I to ). N-Salicyloyltryptamine also exhibits anticonvulsant, anti-inflammatory, analgesic, and vasorelaxation effect [1] - [5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 31384-98-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-147377. | |
| NSC23925 | NSC23925 is a novel, selective and effective P-glycoprotein ( Pgp ) inhibitor. Uses: Scientific research. Group: Signaling pathways. CAS No. 858474-14-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-19626. | |
| NSC59984 | NSC59984 induces mutant p53 protein degradation via MDM2 and the ubiquitin-proteasome pathway [1]. NSC59984 acts by targeting GOF-mutant p53 and stimulates p73 to restore the p53 pathway signaling [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 803647-40-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19726. | |
| NSD2-PWWP1-IN-2 | NSD2-PWWP1-IN-2 (compound 33) is a potent NSD2-PWWP1 inhibitor with an IC 50 value of 1.49 μM. NSD2-PWWP1-IN-2 has the potential for the research of cancer [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2797183-32-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-171120. | |
| N-sec-butyl Pentylone hydrochloride | N-sec-butyl Pentylone hydrochloride is a cathinone. Uses: Scientific research. Group: Signaling pathways. CAS No. 17763-05-2. Pack Sizes: 1 mg. Product ID: HY-402939A. | |
| NSI-189 | NSI-189 is an orally active chemical entity with enhanced neurogenic activity. NSI-189 up-regulates neurogenic factors such as BDNF (brain derived-neurotrophic factor) and SCF. NSI-189 exhibits anti-depressant effect. NSI-189 enhances synaptic plasticity and reduces cognitive dysfunction. NSI-189 holds potential for psychiatric disorder research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1270138-40-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13999. | |
| NSI-189 phosphate | NSI-189 is an orally active chemical entity with enhanced neurogenic activity. NSI-189 up-regulates neurogenic factors such as BDNF (brain derived-neurotrophic factor) and SCF. NSI-189 exhibits anti-depressant effect. NSI-189 enhances synaptic plasticity and reduces cognitive dysfunction. NSI-189 holds potential for psychiatric disorder research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1270138-41-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-13999A1. | |
| NSP-805 | NSP-805 is a potent and selective inhibitor of guinea pig cardiac phosphodiesterase 3 (PDE3) , and a cardiotonic agent with vasodilator properties. Uses: Scientific research. Group: Signaling pathways. CAS No. 125068-54-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 20 mg. Product ID: HY-19102. | |
| N-Stearoylglycine | N-stearoylglycine is a lipid and has a small ionizable polar headgroup whose charge is pH dependent and whose amide moiety can form H-bonded network between adjacent molecules in ordered films [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Stearoylglycine; N-Octadecanoylglycine. CAS No. 6333-54-6. Pack Sizes: 250 mg. Product ID: HY-W141932. | |
| N-Stearoyl Taurine | Several different arachidonoyl amino acids, including N-arachidonoyl dopamine (NADA) and N-arachidonoyl serine (ARA-S), have been isolated and characterized from bovine brain.1 During mass spectral lipidomic analysis of rat brain, a series of fatty acyl amides of a third amino acid, taurine, is discovered.2 This novel class of compounds is present in kidney and activates members of the transient receptor potential (TRP) family of calcium channels.3 N-Stearoyl taurine is a prominent amino-acyl endocannabinoid isolated from rat brain during lipidomics profiling. Uses: Scientific research. Group: Signaling pathways. CAS No. 63155-80-6. Pack Sizes: 1 mg (2.55 mM * 1 mL in Methanol). Product ID: HY-120964. | |
| N-Succinimidyl-S-acetylthioacetate | N-Succinimidyl S-acetylthioacetate (SATA), a protein modification agent, introduces thiol-groups into protein molecules. N-Succinimidyl S-acetylthioacetate adds sulfhydryl groups to proteins and other amine-containing molecules in a protected form [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: SATA. CAS No. 76931-93-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135233. | |
| NT-0796 | NT-0796 is an orally active, selective and CNS-penetrant NLRP3 inflammasome inhibitor. NT-0796 inhibits IL-1β release in human PBMC cells with an IC 50 value of 0.32 nM. NT-0796 is an isopropyl ester that undergoes intracellular conversion to NDT-19795, the carboxylic acid active species. NT-0796 reverses high fat diet-induced obesity, systemic inflammation and astrogliosis in the diet-induced obesity mouse model. NT-0796 is promising for research of neurodegenerative disorders, including Alzheimers disease, Parkinsons disease, multiple sclerosis, and amyotrophic lateral sclerosis [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2272917-13-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156438. | |
| NT219 | NT219 is a potent and dual inhibitor of insulin receptor substrates 1/2 ( IRS1/2 ) and STAT3. IRS1/2 and STAT3 are major signaling junctions regulated by various oncogenes. NT219 affects IRS1/2 degradation and inhibits STAT3 phosphorylation. NT219 has the potential for the research of cancer diseases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1198078-60-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145935. | |
| N-tert-Boc-cis-4-fluoro-L-proline | N-tert-Boc-cis-4-fluoro-L-proline is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Peptides. CAS No. 203866-13-1. Pack Sizes: 5 g. Product ID: HY-W003222. | |
| N-tert-Butyl-α-phenylnitrone | N-tert-Butyl-α-phenylnitrone is a nitrone-based free radical scavenger that forms nitroxide spin adducts. N-tert-Butyl-α-phenylnitrone inhibits COX2 catalytic activity. N-tert-Butyl-α-phenylnitrone has potent ROS scavenging, anti-inflammatory, neuroprotective, anti-aging and anti-diabetic activities, and can penetrate the blood-brain barrier [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3376-24-7. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg; 500 mg. Product ID: HY-128463. | |
| N-Tetradecanoyl-L-homoserine lactone | N-Tetradecanoyl-L-homoserine lactone is a short-chained N-acyl homoserine lactone (AHL). Diatoms are frequently found in association with Proteobacteria, many members of which employ cell-to-cell communication via AHLs in aquatic habitats [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 202284-87-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-133684. | |
| NTNCB hydrochloride | NTNCB (Compound 11) hydrochloride is a potent and selective neuropeptide Y Y5 (NPY Y5) receptor antagonist with a K i of 8 nM against human Y5 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 191931-56-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107733. | |
| N-trans-Caffeoyltyramine | N-TRANS-CaffeoyLtyramine is an effective inflammatory response regulator, which has antioxidant activity and anticoagulation effects [1]. Uses: Scientific research. Group: Natural products. CAS No. 103188-48-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N8241. | |
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