MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Lipoic acid | Lipoic acid ((R)-(+)-α-Lipoic acid) is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. (R)-(+)-α-Lipoic acid is more effective than racemic Lipoic acid. Uses: Scientific research. Group: Natural products. Alternative Names: (R)-(+)-α-Lipoic acid; R-(+)-Thioctic acid. CAS No. 1200-22-2. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-18733. |  |
| Lipopolysaccharides, from E. coli O111:B4 | Lipopolysaccharides, from E. coli O111:B4 (LPS, from Escherichia coli (O111:B4)) are endotoxins and TLR4 activators extracted from Escherichia coli (E. coli O111:B4) and are classified as S (smooth) type LPS. Lipopolysaccharides (LPS), from E. coli O111:B4 possess the typical three-part structure: O-antigen, R3-type core oligosaccharide, and lipid A. Lipopolysaccharides (LPS), from E. coli O111:B4 activate TLR-4 in immune cells and can cause significant gastric diseases. Lipopolysaccharides (LPS), from E. coli O111:B4 can be used to induce cellular inflammation and establish animal models related to inflammation[1][2][3][4][5][6][7][8][9].It is recommended to prepare a stock solution of ?2 mg/mL and ensure that it is fully mixed and dissolved. Due to the adsorption characteristics of LPS, low adsorption centrifuge tubes should be used for aliquoting and storage. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: LPS, from Escherichia coli (O111:B4). Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-D1056A1. | |
| Lipopolysaccharides, from E. coli O55:B5 | Lipopolysaccharides, from E. coli O55:B5 (LPS, from Escherichia coli (O55:B5)) are endotoxins and TLR4 activators extracted from Escherichia coli (E. coli O55:B5) and are classified as S (smooth) type LPS. Lipopolysaccharides, from E. coli O55:B5 possess the typical three-part structure: O-antigen, core oligosaccharide, and lipid A. Lipopolysaccharides, from E. coli O55:B5 activate TLR-4 in immune cells, exhibit high pyrogenicity, and demonstrate dose and serotype specificity. Lipopolysaccharides, from E. coli O55:B5 can be used to induce cellular inflammation and establish animal models related to inflammation[1][2][3][4][5][6][7]. It is recommended to prepare a stock solution of ?2 mg/mL. Vortex thoroughly for more than 10 minutes. Due to the adsorption characteristics of LPS, low adsorption centrifuge tubes should be used for aliquoting and storage. Uses: Scientific research. Group: Natural products. Alternative Names: LPS. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D1056. | |
| Lipoteichoic acid | Lipoteichoic acid is an orally effect anti-inflammatory and antitumor agent. Lipoteichoic acid is a crucial immune molecule in Gram-positive bacteria that activates the complement system by inducing C3 and inhibiting CD55. Lipoteichoic acid regulates macrophage autophagy through the PI3K/Akt/mTOR pathway. Lipoteichoic acid induces lung damage in mice. Lipoteichoic acid inhibits the production of melanin [1] [2] [3] [4] [5] [6] [7]. Uses: Scientific research. Group: Natural products. CAS No. 56411-57-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N9481. | |
| Lipoxin A4 | Lipoxin A4 (LXA4), an endogenous lipoxygenase-derived eicosanoid mediator, has potent dual pro-resolving and anti-inflammatory properties [1]. Lipoxin A4 inhibits proliferation and inflammatory cytokine/chemokine production of human epidermal keratinocytes (NHEKs) associated with the ERK1/2 and NF-kB pathways [2]. Lipoxin A4 inhibits serum amyloid A (SAA)-mediated IL-8 release with an IC 50 value of 25.74 nM [3]. Uses: Scientific research. Group: Natural products. Alternative Names: LXA4. CAS No. 89663-86-5. Pack Sizes: 25 μg (283.71 μM * 250 μL in Ethanol). Product ID: HY-113509. | |
| Liproxstatin-1 | Liproxstatin-1 is a potent ferroptosis inhibitor and inhibits ferroptotic cell death (IC50=22 nM)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 950455-15-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-12726. | |
| Lipstatin | Lipstatin is a pancreatic lipase inhibitor ( IC 50 =0.14 μM), whose structure is closely related to the known inhibitor, Esterastin. Lipstatin inhibits the absorption of triglycerides without affecting the absorption of oleic acid. Lipstatin has no inhibitory effects on other pancreatic enzymes, such as phospholipase A2 and trypsin (<200 μM) [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 96829-59-3. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N2330. | |
| Liquiritigenin | Liquiritigenin, a flavanone isolated from Glycyrrhiza uralensis , is a highly selective estrogen receptor β ( ERβ ) agonist with an EC 50 of 36.5 nM for activation of the ERE tk-Luc. Uses: Scientific research. Group: Natural products. Alternative Names: 4',7-Dihydroxyflavanone. CAS No. 578-86-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-N0377. | |
| (±)-Liquiritigenin | (±)-Liquiritigenin ((±)-4',7-Dihydroxyflavanone) is isolated from Angelica keiskei , a hardy perennial herb of the Umbelliferae family. (±)-Liquiritigenin promotes cell proliferation, has cytoprotective activity and reduces cytotoxicity, and also has antioxidant stress effects [1]. Uses: Scientific research. Group: Natural products. Alternative Names: (±)-4',7-Dihydroxyflavanone. CAS No. 69097-97-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N0377A. | |
| Liquiritin | Liquiritin, a flavonoid isolated from Glycyrrhiza uralensis , is a potent and competitive AKR1C1 inhibitor with IC 50 s of 0.62 μM, 0.61 μM, and 3.72μM for AKR1C1, AKR1C2 and AKR1C3, respectively. Liquiritin efficiently inhibits progesterone metabolism mediated by AKR1C1 in vivo [1]. Liquiritin acts as an antioxidant and has neuroprotective, anti-cancer and anti-inflammatory activity [2]. Uses: Scientific research. Group: Natural products. CAS No. 551-15-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0376. | |
| Lirafugratinib | Lirafugratinib (RLY-4008) is an orally active, irreversible and highly selective FGFR2 inhibitor with an IC 50 of 3 nM. Lirafugratinib covalently binds to Cys491. Lirafugratinib targets FGFR2 primary alterations and resistance mutations and induces tumor regression while sparing other FGFRs [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RLY-4008. CAS No. 2549174-42-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147250. | |
| Lirafugratinib hydrochloride | Lirafugratinib (RLY-4008) hydrochloride is an orally active, irreversible and highly selective FGFR2 inhibitor with an IC 50 of 3 nM. Lirafugratinib hydrochloride covalently binds to Cys491. Lirafugratinib hydrochloride targets FGFR2 primary alterations and resistance mutations and induces tumor regression while sparing other FGFRs [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RLY-4008 hydrochloride. CAS No. 2688040-45-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147250A. | |
| Liraglutide | Liraglutide is a glucagon-like peptide-1 ( GLP-1 ) receptor agonist used clinically to treat type 2 diabetes mellitus. Uses: Scientific research. Group: Peptides. CAS No. 204656-20-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0014. | |
| Liranaftate | Liranaftate (Piritetrate) is a squalene epoxidase inhibitor with anti-fungicidal activities. Liranaftate can be used for the research of dermatophytes. Liranaftate also suppresses fungal element-promoted production of IL-8 and experimental inflammation [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Piritetrate; M-732. CAS No. 88678-31-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0348. | |
| Lirentelimab | Lirentelimab (AK002) is a humanized IgG1 monoclonal antibody that targets sialic acid-binding Ig-like lectin 8 ( SIGLEC8 ). Lirentelimab induces cell apoptosis of IL-5-activated eosinophils and inhibits IgE-mediated mast cell activation. Lirentelimab can be used for the research of eosinophilic gastritis and duodenitis [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: AK002; Antolimab. CAS No. 2283348-97-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99371. | |
| Lirilumab | Lirilumab (IPH2102) is an anti-KIR monoclonal antibody, and shows antitumor activity. Lirilumab can be used in Leukemia, squamous cell carcinoma of the head and neck (SCCHN) research [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: IPH2102. CAS No. 1000676-41-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99208. | |
| Liriodenine | Liriodenine (Spermatheridine; VLT045) is an aporphine alkaloid isolated from the plant Mitrephora sirikitiae and has anti-cancer activities [1]. Liriodenine induces cell apoptosis , activates the intrinsic pathway by induction of caspase-3 and caspase-9 [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Spermatheridine; VLT045. CAS No. 475-75-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N3376. | |
| Liriopesides B | Liriopesides B (Nolinospiroside F) is a steroidal saponin isolated from Ophiopogon japonicas. Liriopesides B has anti-oxidative and anti-aging effects [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Nolinospiroside F. CAS No. 87425-34-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N5135. | |
| Lisaftoclax | Lisaftoclax (compound 6) is a dual Bcl-2 and Bcl-xl inhibitor with anti-tumor activity, extracted from patent WO2018027097A1. Lisaftoclax exhibits IC 50 values of 2 nM and 5.9 nM for Bcl-2 and Bcl-xl, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: APG-2575; Bcl-2/Bcl-xl inhibitor 1. CAS No. 2180923-05-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129179. | |
| Lisavanbulin | Lisavanbulin (BAL-101553) is the prodrug of the microtubule targeting agent Avanbulin (BAL 27862) (HY-106008). Lisavanbulin exhibits antitumor activity, especially in tumors that express high levels of end-binding protein 1 [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAL-101553. CAS No. 1263384-43-5. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-19916. | |
| Lisavanbulin dihydrochloride | Lisavanbulin (BAL-101553) dihydrochloride is the prodrug of the microtubule targeting agent Avanbulin (BAL 27862) (HY-106008). Lisavanbulin dihydrochloride exhibits antitumor activity, especially in tumors that express high levels of end-binding protein 1 [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAL-101553 dihydrochloride. CAS No. 1387574-54-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-19916A. | |
| Lisinopril | Lisinopril (MK-521) is angiotensin-converting enzyme inhibitor, used in treatment of hypertension, congestive heart failure, and heart attacks. Uses: Scientific research. Group: Natural products. Alternative Names: MK-521. CAS No. 76547-98-3. Pack Sizes: 250 mg; 500 mg. Product ID: HY-18206. | |
| Lisinopril dihydrate | Lisinopri dihydrate (MK-521 dihydrate) is angiotensin-converting enzyme inhibitor, used in treatment of hypertension, congestive heart failure, and heart attacks. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-521 dihydrate. CAS No. 83915-83-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-18206A. | |
| (±)-Lisofylline | (±)-Lisofylline ((±)-Lisophylline) is the racemate of Lisofylline. Lisofylline inhibits the generation of phosphatidic acid and free fatty acids. Lisofylline also blocks the release of pro-inflammatory cytokines in oxidative tissue injury, in response to cancer chemotherapy and in experimental sepsis. Lisofylline can be used for Type 1 diabetes research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (±)-Lisophylline. CAS No. 6493-6-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-126042. | |
| L-Isoleucine | L-Isoleucine is an orally active branched chain amino acid, which is the L-enantiomer of isoleucine. L-Isoleucine has a role as a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite, a plant metabolite, a human metabolite, an algal metabolite and a mouse metabolite. L-Isoleucine regulates the inflammatory response to protect against pathogens in vivo and in vitro [1]. Uses: Scientific research. Group: Natural products. CAS No. 73-32-5. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-N0771. | |
| L-Isoleucine-1-13C | L-Isoleucine-1- 13 C is the 13 C-labeled L-Isoleucine. L-isoleucine is a nonpolar hydrophobic amino acid[1]. L-Isoleucine is an essential amino acid. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 81202-01-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-N0771S4. | |
| L-Isoleucine-13C6 | L-Isoleucine- 13 C 6 is the 13 C-labeled L-Isoleucine. L-isoleucine is a nonpolar hydrophobic amino acid[1]. L-Isoleucine is an essential amino acid. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 201740-82-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N0771S. | |
| L-Isoleucine-d10 | L-Isoleucine-d 10 is the deuterium labeled L-Isoleucine. L-isoleucine is a nonpolar hydrophobic amino acid[1]. L-Isoleucine is an essential amino acid. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 35045-71-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N0771S3. | |
| Lissamine rhodamine B | Lissamine rhodamine B is a red-fluorescent dye, it is a derivative of rhodamine. Lissamine rhodamine B can be used as a fluorescent probe to develop competitive aptamer fluorescence anisotropy/polarization (FA/FP) assays [1] [2]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 2609-88-3. Pack Sizes: 100 mg. Product ID: HY-117468. | |
| Lisuride | Lisuride is an orally active dopamine D2 receptors agonist. Lisuride, as an ergot derivative, can be used for the research of Parkinson's disease, migraine, and high prolactin levels [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 18016-80-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-12713. | |
| Lisuride maleate | Lisuride (maleate) is a potent agonist of dopamine with a probably direct action on dopaminergic receptors. Lisuride (maleate) is an ergot derivative. Lisuride (maleate) releases the premenstrual mastalgia without significant side effects [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 19875-60-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-110080. | |
| LIT-001 | LIT-001 is the first nonpeptide oxytocin receptor (OT-R) agonist (EC50=55 nM; Ki=226 nM). LIT-001 improves social interaction in a mouse model of autism[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2245072-21-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124733A. | |
| Lithium 3,5-diiodosalicylate | Lithium 3,5-diiodosalicylate is a compound used in the study of bipolar disorder and other psychiatric disorders. It contains lithium and a salicylate. Lithium 3,5-diiodosalicylate works by affecting the levels of certain neurotransmitters in the brain, including dopamine and serotonin. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: 3,5-Diiodosalicylic acid lithium salt. CAS No. 653-14-5. Pack Sizes: 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-W250174. | |
| Lithium carbonate | Lithium carbonate (Carbolithium) is a biochemical reagent that can be used as a biological material or organic compound for life science related research [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Carbolithium; Lithium carbonate. CAS No. 554-13-2. Pack Sizes: 25 g. Product ID: HY-Y0292. | |
| Lithium chloride, 99.3%-T | Lithium chloride, 99% (LiCl, Premium grade) is a biochemical reagent that can be used as a biological material or organic compound for life science related research[1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: LiCl, Premium grade. CAS No. 7447-41-8. Pack Sizes: 50 mg. Product ID: HY-Y0649. | |
| Lithium chloride hydrate | Lithium chloride hydrate, an orally active mood stabilizer, is a potent virus inhibitor and effective immunomodulatory agent. Lithium chloride hydrate has antidepressant activity by inhibiting GSK3β and promoting neurogenesis. Lithium chloride hydrate alleviates cognition dysfunction and the symptoms of acute mania and depression. Lithium chloride hydrate can also be used for research of virus infection and Alzheimer's disease [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: hydrate/monohydrateortrihydrate. CAS No. 85144-11-2. Pack Sizes: 100 mg. Product ID: HY-W094474. | |
| Lithium citrate tetrahydrate | Lithium citrate (Litarex) tetrahydrate is the major active ingredient of Garcinia cambogia. Lithium citrate tetrahydrate competitively inhibits ATP citrate lyase with weight loss benefits. Lithium citrate tetrahydrate effective inhibits stones formation and also inhibits HIF , and has antioxidation, anti-inflammation and anti-tumor effects [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Litarex tetrahydrate. CAS No. 6080-58-6. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-B1295. | |
| Lithium dodecyl sulfate | Lithium dodecyl sulfate is an anionic detergent and surfactant that can be used in place of SDS for electrophoresis under low temperatures. Lithium dodecyl sulfate can be used for synthesis of nanomaterials and chromatography [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 2044-56-6. Pack Sizes: 5 g; 10 g. Product ID: HY-W099535. | |
| Lithocholic acid | Lithocholic acid is a toxic secondary bile acid that can promote intrahepatic cholestasis and promote tumorigenesis. Lithocholic acid is also a FXR antagonist and a PXR/SXR agonist [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. CAS No. 434-13-9. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0172. | |
| Lithocholic acid 3-sulfate disodium | Lithocholic acid 3-sulfate disodium salt is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Sulfolithocholic acid disodium. CAS No. 64936-81-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-113238A. | |
| Lithospermic acid | Lithospermic acid ((+)-Lithospermic acid) is a plant-derived polycyclic phenolic carboxylic acid isolated from Salvia miltiorrhiza, and has the anti-oxidative and hepatoprotective activity on carbon tetrachloride (CCl4)-induced acute liver damage in vitro and in vivo[1]. Uses: Scientific research. Group: Natural products. Alternative Names: (+)-Lithospermic acid. CAS No. 28831-65-4. Pack Sizes: 5 mg; 10 mg; 20 mg. Product ID: HY-N0823. | |
| Litifilimab | Litifilimab is a humanized IgG1-κ antibody targeting to C-type lectin domain family 4 member C ( CLEC4C ). Litifilimab can be used for cutaneous lupus erythematosus (CLE) study [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BIIB059. CAS No. 2407378-48-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9990. | |
| Litronesib | Litronesib (LY2523355) is a selective mitosis-specific kinesin Eg5 inhibitor, with antitumor activity[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY2523355. CAS No. 910634-41-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14846. | |
| Livmoniplimab | Livmoniplimab (ABBV-151) is a monoclonal antibody against GARP/TGF-β1 that can inhibit the release of active TGF-β1. Livmoniplimab has anti-tumor activity in colon cancer mice. Livmoniplimab can be used for the study of locally advanced or metastatic solid tumors [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ABBV-151; ARGX-115. CAS No. 2412004-88-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99708. | |
| Lixisenatide | Lixisenatide is a GLP-1 receptor agonist. Lixisenatide inhibits the inflammatory response through down regulation of proinflammatory cytokines, and blocks of cellular signaling pathways. Lixisenatide decreases atheroma plaque size and instability in Apoe -/- Irs 2+/- mice by reprogramming macrophages towards an M2 phenotype, which leads to reduced inflammation [2] [3] [5]. Uses: Scientific research. Group: Peptides. CAS No. 320367-13-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P0119. | |
| Lixisenatide acetate | Lixisenatide acetate is a glucagon-like peptide-1 (GLP-1) receptor agonist that can be used in the treatment of type 2 diabetes mellitus (T2DM). Uses: Scientific research. Group: Peptides. CAS No. 1997361-87-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0119A. | |
| Lixivaptan | Lixivaptan (VPA-985, WAY-VPA 985) is an orally active and selective vasopressin receptor V2 antagonist, with IC 50 values of 1.2 and 2.3 nM for human and rat V2, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: VPA-985; WAY-VPA 985. CAS No. 168079-32-1. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14185. | |
| Lixosicone | Lixosicone is a signaling-specific inhibitor of the cannabinoid receptor 1 (CB1-SSi). Lixosicone plays an important role in Cannabis use disorder (CUD) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AEF0117. CAS No. 1610878-71-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156831. | |
| Lixudebart | Lixudebart is a humanized immunoglobulin G1-kappa, anti-CLDN1 monoclonal antibody [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2749515-10-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990045. | |
| Lixumistat acetate | Lixumistat (IM156; HL156A; HL271) acetate, a chemical derivative of Metformin (HY-B0627), is a potent and orally active AMPK activator that increases AMPK phosphorylation. Lixumistat (acetate) attenuates aging-associated cognitive impairment in animal model [1] [2]. Lixumistat (acetate) is a potent oxidative phosphorylation (OXPHOS) inhibitor which can be used for the research of solid tumors [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IM156; HL156A; HL271 acetate. CAS No. 1422365-94-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136093A. | |
| LJH685 | LJH685 is a potent, ATP-competitive and selective RSK inhibitor, inhibits RSK1, 2, and 3 biochemical activities with IC50s of 6, 5, 4 nM, respectively[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1627710-50-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-19712. | |
| LJI308 | LJI308 is a potent pan-ribosomal S6 kinase (RSK) inhibitor, with IC50s of 6 nM, 4 nM, and 13 nM for RSK1, RSK2, and RSK3, respectively. LJI308 inhibits the phosphorylation of RSK (T359/S363) and YB-1 (S102) after irradiation, treatment with EGF, and in cells expressing a KRAS mutation[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1627709-94-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19713. | |
| LK-2 | LK-2 is an antagonist for ASIC1a with a K d of 1.9 μM. LK-2 reduces glutamate-induced ASIC1a current-enhancement with an IC 50 of 6.6 μM. LK-2 exhibits neuroprotective efficacy in mouse ischemic stroke model, with improved motor and coordination skills. LK-2 is blood-brain barrier (BBB) penetrable [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2649762-09-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-164284. | |
| LKY-047 | LKY-047, a Decursin derivative, is a potent and selective reversible competitive cytochrome P45022J2 (CYP2J2) inhibitor with an IC50 of 1.7 ?M. LKY-047 is inactive against other human P450s, such as CYPs 1A2, 2A6, 2B6, 2C8, 2C9, 2C19, 2D6, 2E1, and 3A[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1954681-29-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117026. | |
| L-Kynurenine | L-Kynurenine is a metabolite of the amino acid L-tryptophan. L-Kynurenine is an aryl hydrocarbon receptor agonist. Uses: Scientific research. Group: Natural products. CAS No. 2922-83-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-104026. | |
| L-Kynurenine-d4 | L-Kynurenine-d4 is the deuterium labeled L-Kynurenine. L-Kynurenine is a metabolite of the amino acid L-tryptophan. L-Kynurenine is an aryl hydrocarbon receptor agonist[1][2]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 2672568-86-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-104026S. | |
| L-Kynurenine (Standard) | L-Kynurenine (Standard) is the analytical standard of L-Kynurenine. This product is intended for research and analytical applications. L-Kynurenine is a metabolite of the amino acid L-tryptophan. L-Kynurenine is an aryl hydrocarbon receptor agonist. Uses: Scientific research. Group: Natural products. CAS No. 2922-83-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-104026R. | |
| LL-37, human | LL-37, human is a 37-residue, amphipathic, cathelicidin-derived antimicrobial peptide, which exhibits a broad spectrum of antimicrobial activity. LL-37, human could help protect the cornea from infection and modulates wound healing [1] [2] [3]. Uses: Scientific research. Group: Peptides. CAS No. 154947-66-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P1222. | |
| LL-37, human TFA | LL-37, human TFA is a 37-residue, amphipathic, cathelicidin-derived antimicrobial peptide, which exhibits a broad spectrum of antimicrobial activity. LL-37, human TFA could help protect the cornea from infection and modulates wound healing[1][2][3]. Uses: Scientific research. Group: Peptides. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P1222A. | |
| L-Lactate dehydrogenase, Microorganism | L-Lactate dehydrogenase, Microorganism (LAD) is a redox enzyme. L-Lactate dehydrogenase catalyzes the reduction of pyruvate to L-lactate by NADH in vivo with absolute enantiospecificity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LAD. CAS No. 9001-60-9. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P2807. | |
| L-Lactate Dehydrogenase, rabbit muscle | L-Lactate Dehydrogenase, rabbit muscle is a biological material or organic compound that can be used in life science research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 9001-60-9. Pack Sizes: 2.5 KU; 25 KU. Product ID: HY-P2807I. | |
| L-Lactic acid | L-Lactic acid is a buildiing block which can be used as a precursor for the production of the bioplastic polymer poly-lactic acid. L-Lactic acid has antiproliferative activity [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: (S)-2-Hydroxypropanoic acid. CAS No. 79-33-4. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-Y0479. | |
| L-Lactic acid-13C3 | L-Lactic acid- 13 C 3 is a 13 C-labeled L-Lactic acid (HY-Y0479). L-Lactic acid- 13 C 3 can be used for lactate metabolism research [1]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: (S)-2-hydroxypropanoic-13-C3. CAS No. 87684-87-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-Y0479S. | |
| L-Lactic acid-13C3 (sodium) (20% in water) | L-Lactic acid- 13 C 3 ((S)-2-hydroxypropanoic- 13 C 3 ) sodium (20% in water) is the 13 C labeled L-Lactic acid. L-Lactic acid- 13 C 3 sodium (20% in water) can be used for lactate metabolism research [1]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: (S)-2-hydroxypropanoic- 13 C3 sodium. CAS No. 201595-71-3. Pack Sizes: 1 mg (200 mg/mL * 5 μL in Water); 5 mg (200 mg/mL * 25 μL in Water); 10 mg (200 mg/mL * 50 μL in Water); 25 mg (200 mg/mL * 125 μL in Water); 50 mg (200 mg/mL * 250 μL in Water). Product ID: HY-Y0479AS. | |
| L-Lactic acid-d3 sodium | Sodium (S)-2-hydroxypropanoate-d 3 is the deuterium labeled Sodium (S)-2-hydroxypropanoate[1]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: (S)-2-Hydroxypropanoic acid-d3 sodium. CAS No. 285979-84-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-W040233S. | |
| L-Lactic acid lithium | L-Lactic acid lithium ? L-Lactic acid (HY-Y0479) ???????, ???????????L-Lactic acid ???????????????????. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: (S)-2-Hydroxypropanoic acid lithium. CAS No. 27848-80-2. Pack Sizes: 1 g; 5 g; 10 g. Product ID: HY-D0884. | |
| L,L-Dityrosine | L,L-Dityrosine (o,o'-Dityrosine) is a constituent of acid hydrolysates of a number of biological materials, including the insect cuticular resilin [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: o,o'-Dityrosine. CAS No. 63442-81-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-101552A. | |
| L,L-Dityrosine hydrochloride | L,L-Dityrosine hydrochloride (o,o'-Dityrosine hydrochloride) is a constituent of acid hydrolysates of a number of biological materials, including the insect cuticular resilin [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: o,o'-Dityrosine hydrochloride. CAS No. 221308-01-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-101552B. | |
| L-Leucine | L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Leucine. CAS No. 61-90-5. Pack Sizes: 100 mg; 250 mg; 500 mg. Product ID: HY-N0486. | |
| L-Leucine-13C | L-Leucine- 13 C is the 13 C-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway[1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 74292-94-7. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-N0486S1. | |
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