MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Ondansetron-d3 hydrochloride | Ondansetron-d 3 (hydrochloride) is the deuterium labeled Ondansetron hydrochloride. Ondansetron hydrochloride (GR 38032 hydrochloride) is a serotonin 5-HT3 receptor antagonist used mainly as anantiemetic (to treat nausea and vomiting), often following chemotherapy[1][2]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 1346605-02-4. Pack Sizes: 1 mg. Product ID: HY-B0002S. |  |
| Ondansetron hydrochloride | Ondansetron hydrochloride (GR 38032 hydrochloride; SN 307 hydrochloride) is a serotonin 5-HT3 receptor antagonist used mainly as anantiemetic (to treat nausea and vomiting), often following chemotherapy. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GR 38032 hydrochloride; SN 307 hydrochloride. CAS No. 99614-01-4. Pack Sizes: 50 mg; 100 mg; 1 g. Product ID: HY-B0002. | |
| Ondansetron hydrochloride dihydrate | Ondansetron (GR 38032) hydrochloride dehydrate is an orally active, highly selective and competitive 5-HT 3 receptor antagonist (crosses the blood-brain barrier). Ondansetron hydrochloride dehydrate can be used in studies of preventing nausea and vomiting associated with cancer chemotherapy, radiation therapy and surgery [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GR 38032 hydrochloride dihydrate; SN 307 hydrochloride dihydrate. CAS No. 103639-04-9. Pack Sizes: 50 mg; 100 mg; 1 g; 5 g. Product ID: HY-B0002A. | |
| ONO-4059 analog | ONO-4059 analog is an analogue of ONO-4059, and ONO-4059 (HY-15771) is a highly potent and selective Btk inhibitor. Uses: Scientific research. Group: Signaling pathways. CAS No. 1351635-67-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18951. | |
| ONO-AE 248 | ONO-AE 248 is a selective EP3 receptor agonist with cardioprotective activity. ONO-AE 248 reduces myocardial infarction size by selectively binding to the EP3α receptor in mice. The cardioprotective effect of ONO-AE 248 is independent of hemodynamic effects. The mechanism of ONO-AE 248 may involve activation of protein kinase C and opening of K(ATP) channels [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 211230-67-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-12184. | |
| ONO-AE3-208 | ONO-AE3-208 is a selective and orally active EP4 receptor antagonist with a K i of 1.3 nM. ONO-AE3-208 shows less potently affects EP3, FP, and TP receptors (K i of 30 nM, 790 nM, and 2400 nM, respectively). ONO-AE3-208 suppresses cell invasion, migration, and metastasis of prostate cancer [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AE 3-208. CAS No. 402473-54-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-50901. | |
| Ononin | Ononin is an orally active isoflavone. Ononin inhibits the ERK/JNK/p38 and PI3K/Akt/mTOR pathways. Ononin regulates Apoptosis. Ononin has anti-tumor effects on laryngeal cancer and lung cancer. Ononin has neuroprotective effects. Ononin alleviates endoplasmic reticulum stress and diabetic nephropathy [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Natural products. Alternative Names: Ononoside; Formononetin 7-O-β-D-glucopyranoside. CAS No. 486-62-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0270. | |
| ONPG | ONPG is a colorimetric and spectrophotometric substrate for detection of β-galactosidase activity. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: 2-Nitrophenyl β-D-galactopyranoside. CAS No. 369-07-3. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-15926. | |
| Onradivir | Onradivir is a potent anti- influenza virus agent [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ZSP1273. CAS No. 2200336-20-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145586. | |
| Ontuxizumab | Ontuxizumab (MORAb-004) is a humanized IgG1/κ anti-endosialin (TEM-1 or CD248) monoclonal antibody with antitumor effects. Ontuxizumab can be used for the research of cancer [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MORAb-004. CAS No. 946415-62-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99778. | |
| Onvansertib | NMS-1286937 is a potent, selective and orally available PLK1 inhibitor, with an IC 50 of 2 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NMS-1286937; NMS-P937. CAS No. 1034616-18-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15828. | |
| Oosporein | Oosporein is a red crystalline metabolite produced by a toxin-producing strain of Chaetomium trilaterale. Chaetomium trilaterale is isolated from moldy Peanuts. Oosporein inhibits plant growth and produces phytotoxic effects [1]. Uses: Scientific research. Group: Natural products. CAS No. 475-54-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N7719. | |
| O,O,S-Trimethyl ester phosphorothioic acid | O,O,S-Trimethyl ester phosphorothioic acid is a chemical substance with biological activity for studying renal fibrosis. O,O,S-Trimethyl ester phosphorothioic acid can be used as an experimental model for studying renal fibrosis. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 152-20-5. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-30099. | |
| OP-1074 | OP-1074, a pure anti-estrogen drug, is a selective ER degrader ( PA-SERD ) with specific anti-estrogenic activity against ERα and ERβ, inhibiting 17β-estradiol (E2)-stimulated transcription with IC 50 values of 1.6 and 3.2 nM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1443752-76-8. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-125263. | |
| Opaganib | Opaganib (ABC294640) is a selective, competitive sphingosine kinase 2 ( SK2 ) inhibitor with K i of 9.8 μM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABC294640. CAS No. 915385-81-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16015. | |
| OPC 4392 hydrochloride | OPC 4392 hydrochloride is an agonist for presynaptic dopamine receptor and an antagonist for postsynaptic D2 receptor. OPC 4392 reverses the Reserpine (HY-N0480)-induced dopamine accumulation, inhibits Apomorphine (HY-12723)-induced stereotypic and climbing behaviors in mouse models [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1329509-60-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-106781A. | |
| Opevesostat | Opevesostat (MK-5684; ODM-208) is an orally active and selective CYP11A1 inhibitor. Opevesostat has the potential for the research of metastatic castration-resistant prostate cancer (mCRPC) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-5684; ODM-208. CAS No. 2231294-96-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156628. | |
| o-Phenanthroline | o-Phenanthroline (1,10-Phenanthroline), a metal chelator, prevents the induction of chromosomal aberrations in streptozotocin-treated cells. o-Phenanthroline (1,10-Phenanthroline) forms a red chelate with Fe 2+ that absorbs maximally at 510 nm. o-Phenanthroline (1,10-Phenanthroline) is also a MMP inhibitor [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: 1,10-Phenanthroline. CAS No. 66-71-7. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-W004544. | |
| o-Phenanthroline monohydrate | o-Phenanthroline (1,10-Phenanthroline) monohydrate, a metal chelator, prevents the induction of chromosomal aberrations in streptozotocin-treated cells. o-Phenanthroline monohydrate forms a red chelate with Fe 2+ that absorbs maximally at 510 nm. o-Phenanthroline (1,10-Phenanthroline) monohydrate is also a MMP inhibitor [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: 1,10-Phenanthroline monohydrate. CAS No. 5144-89-8. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-Y1841. | |
| Ophiobolin A | Ophiobolin A, a fungal metabolite and a phytotoxin, is a potent and irreversibly inhibitor of calmodulin-activated cyclic nucleotide phosphodiesterase , with an IC 50 value of 9 μM. Ophiobolin A antimicrobial and anticancer activity [1]. Uses: Scientific research. Group: Natural products. CAS No. 4611-5-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N6781. | |
| Ophiopogonanone A | Ophiopogonanone A is a homoisoflavonoidal compound isolated as a constitutent of Ophiopogonis tuber [1]. Uses: Scientific research. Group: Natural products. CAS No. 75239-63-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N6059. | |
| Ophiopogonin D | Ophiopogonin D, isolated from the tubers of Ophiopogon japonicus , is a rare naturally occurring C 29 steroidal glycoside [1]. Ophiopogonin D is a CYP2J3 inducer that significantly inhibits Ang II induced NF-κB nuclear translocation, IκBα down-regulation, intracellular Ca 2+ overload and activation of pro-inflammatory cytokines by increasing the expression of CYP2J2/EETs and PPARα in human umbilical vein endothelial cells (HUVECs). Ophiopogonin D has been used to treat inflammatory and cardiovascular diseases for thousands of years [2]. Uses: Scientific research. Group: Natural products. CAS No. 945619-74-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-N0515. | |
| O-Phospho-L-serine | O-Phospho-L-serine is the immediate precursor to L-cystein in the serine synthesis pathway, and an agonist at the group III mGluR receptors (mGluR4, mGluR6, mGluR7, and mGluR8); O-Phospho-L-serine also acts as a weak antagonist for mGluR1 and a potent antagonist for mGluR2 [1]. Uses: Scientific research. Group: Natural products. Alternative Names: L-Serine O-phosphate; L-SOP. CAS No. 407-41-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-15129. | |
| O-Phospho-L-threonine | O-Phospho-L-threonine is a threonine derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 1114-81-4. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-113014. | |
| Ophthalmic acid | Ophthalmic acid, an analogue of GSH, is a marker of oxidative stress and hepatic GSH consumption. Ophthalmic acid is an inhibitor of Glyoxalase I reaction [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 495-27-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-126752. | |
| Opicapone | Opicapone (BIA 9-1067) is a potent third-generation catechol-O-methyltransferase ( COMT ) inhibitor for the research of Parkinson's disease and motor fluctuations. Opicapone decreases the ATP content of the cells with an IC 50 of 98 μM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BIA 9-1067. CAS No. 923287-50-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14896. | |
| Opicinumab | Opicinumab (BIIB033) is a monoclonal antibody against LINGO-1 and has potential application in acute optic neuritis and relapse multiple sclerosis [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BIIB033. CAS No. 1422268-07-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99780. | |
| Opiorphin | Opiorphin, an opioid peptide, is a potent enkephalin-inactivating zinc ectopeptidases in human inhibitor. Opiorphin inhibits two enkephalin-catabolizing ectoenzymes, human neutral ecto-endopeptidase, hNEP (EC 3.4.24.11) with an IC 50 value of 11 μM, and human ecto-aminopeptidase, hAP-N (EC 3.4.11.2). Opiorphin displays potent analgesic activity by activating endogenous opioid-dependent transmission [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 864084-88-8. Pack Sizes: 10 mg; 25 mg; 50 mg. Product ID: HY-W345510. | |
| Opipramol | Opipramol (Ensidon) is an atypical tricyclic antidepressant (TCA). Opipramol acts primarily as a sigma (σ) receptor agonist and can potently interact with sigma recognition sites with a K i value of 50 nM. Opipramol can be used for the research of generalized anxiety disorder (GAD) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ensidon; G-33040. CAS No. 315-72-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-118901. | |
| Opnurasib | Opnurasib (JDQ-443) (NVP-JDQ443) is an orally active, potent, selective, and covalent KRAS G12C inhibitor (extracted from patent WO2021120890A1). Opnurasib shows antitumor activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: JDQ-443; NVP-JDQ443. CAS No. 2653994-08-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-139612. | |
| Orange G | Orange G is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Acid Orange GG. CAS No. 1936-15-8. Pack Sizes: 10 g. Product ID: HY-135712. | |
| Orange I | Orange I (α-Naphthol Orange) is an organic azo dye used as a food dye [1]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: α-Naphthol Orange. CAS No. 523-44-4. Pack Sizes: 250 mg; 500 mg; 1 g. Product ID: HY-D0929. | |
| Orantinib | Orantinib (SU6668; TSU-68) is a multi-targeted receptor tyrosine kinase inhibitor with K i s of 2.1 μM, 8 nM and 1.2 μM for Flt-1 , PDGFRβ and FGFR1 , respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SU6668; TSU-68. CAS No. 252916-29-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10517. | |
| Orbifloxacin | Orbifloxacin is a synthetic broad-spectrum fluoroquinolone antibiotic which is approved for use in dogs. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CP-104354. CAS No. 113617-63-3. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B0915. | |
| Orbofiban acetate | Orbofiban acetate is an orally active platelet GPIIb/IIIa antagonist that inhibits platelet aggregation. Uses: Scientific research. Group: Signaling pathways. CAS No. 163250-91-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10304A. | |
| Orcein | Orcein inhibits flavivirus methyltransferases. Uses: Scientific research. Group: Fluorescent dye. CAS No. 1400-62-0. Pack Sizes: 500 mg; 1 g. Product ID: HY-122266. | |
| Orcinol | Orcinol (3,5-Dihydroxytoluene) is an organic compound used in biological dyeing and proteomics research. Orcinol inhibits melanogenesis in B16F10 cells by upregulating the MAPK/ERK signaling pathway, and suppresses the expression of MITF , tyrosinase ( TYR ), TRP1 , and DCT. Orcinol exhibits certain DPPH radical scavenging activity. In addition, Orcinol can alter nitrogen balance in animals. Orcinol holds promise for research in cancer and metabolic diseases [1] [2] [3]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: 3,5-Dihydroxytoluene. CAS No. 504-15-4. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-D0168. | |
| Ordesekimab | Ordesekimab (AMG 714; PRV-015) is a fully human IgG1κ anti- IL-15 ( Interleukin Related ) monoclonal antibody. The binding of Ordesekimab to IL-15 inhibits the interaction of IL-15 with the IL-2Rβ and common γ chain of the IL-15 receptor complex, but not with the IL-15Rα chain. Ordesekimab has the potential for study of nonresponsive celiac disease (NRCD) [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: AMG 714; PRV-015. CAS No. 879293-15-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99410. | |
| Orelabrutinib | Orelabrutinib (ICP-022) is a potent, orally active, and irreversible Bruton's tyrosine kinase (BTK) inhibitor with potential antineoplastic activity. Orelabrutinib prevents both the activation of the B-cell antigen receptor (BCR) signaling pathway and BTK-mediated activation of downstream survival pathways, inhibiting the growth of malignant B-cells that overexpress BTK [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ICP-022. CAS No. 1655504-04-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129390. | |
| Orexin 2 Receptor Agonist | Orexin 2 Receptor Agonist is a potent selective OX2R agonist with an EC 50 of 23 nM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1796565-52-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19320. | |
| Orexin 2 Receptor Agonist 2 | Orexin 2 Receptor Agonist 2 is a selective orexin 2 receptor agonist, extracted from patent WO2017135306A1, example 16 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2114324-60-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138695. | |
| Orexin A (human, rat, mouse) | Orexin A (human, rat, mouse) (Hypocretin-1 (human, rat, mouse)), a 33 amino acid excitatory neuropeptide, orchestrates diverse central and peripheral processes. Orexin A (human, rat, mouse) binds and activates two types of G protein-coupled receptors, the orexin-1 receptor ( OX1R ) and the orexin-2 receptor ( OX2R ). Orexin A (human, rat, mouse) has a role in the regulation of feeding behavior. Orexin A (human, rat, mouse) is an effective anti-nociceptive and anti-hyperalgesic agent in mice and rats [1] [2]. Uses: Scientific research. Group: Peptides. Alternative Names: Hypocretin-1 (human, rat, mouse). CAS No. 205640-90-0. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-106224. | |
| Orexin B, rat, mouse | Orexin B, rat, mouse (Rat orexin B) is an endogenous agonist at Orexin receptor with K i s of 420 and 36 nM for OX1 and OX2, respectively. Uses: Scientific research. Group: Peptides. Alternative Names: Rat orexin B; Orexin B (mouse). CAS No. 202801-92-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1349. | |
| Orexin receptor antagonist 2 | Orexin receptor antagonist 2 (compound 30) is a potent orexin receptor antagonist with pK i s of 7.69 and 9.78. Orexin receptor antagonist 2 has the potential for the research of insomnia [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1457940-75-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-136922. | |
| Orexin receptor antagonist 3 | Orexin receptor antagonist 3 (example 216) is an orexin receptor antagonist, which is extracted from the patent WO2011050198A1 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1293282-55-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-137093. | |
| Orforglipron | Orforglipron (LY3502970) (Compound 67) is an orally active agonist for Glucagon-like peptide-1 receptor ( GLP-1R ), which exhibits potency in ameliorates the type 2 diabete [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY3502970; GLP-1 receptor agonist 1. CAS No. 2212020-52-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-112185. | |
| Org 25543 hydrochloride | Org 25543 hydrochloride is a selective and irreversible GlyT2 inhibitor ( IC 50 : 16 nM). Org 25543 hydrochloride has analgesia effect. Org 25543 hydrochloride ameliorates mechanical allodynia after partial sciatic nerve ligation injury in mice [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 495076-64-7. Pack Sizes: 5 mg. Product ID: HY-107527. | |
| Org 27569 | Org 27569 is a potent CB1 receptor allosteric modulator, which increases agonist binding, yet blocks agonist-induced CB1 signaling. Uses: Scientific research. Group: Signaling pathways. CAS No. 868273-06-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-13288. | |
| ORIC-101 | ORIC-101 is a highly potent and selective glucocorticoid receptor antagonist, with an EC 50 of 5.6 nM. Anti-cancer activity. ORIC-101 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 2222344-98-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-112710. | |
| Oridonin | Oridonin (NSC-250682), a diterpenoid isolated from Rabdosia rubescens , acts as an inhibitor of AKT , with IC 50 s of 8.4 and 8.9 μM for AKT1 and AKT2; Oridonin possesses anti-tumor, anti-bacterial and anti-inflammatory effects. Uses: Scientific research. Group: Natural products. Alternative Names: NSC-250682; Isodonol. CAS No. 28957-04-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-N0004. | |
| Orientin | Orientin is a neuroprotective agentinhibits which has anti-inflammation, anti-oxidative, anti-tumor, and cardio protection properties. Orientin inhibits the levels of IL-6 , IL-1β and TNF-&alpha. Orientin increases IL-10 level. Orientin exhibits neuroprotective effect by inhibits TLR4 and NF-kappa B signaling pathway. Orientin can used in study neuropathic pain [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 28608-75-5. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg. Product ID: HY-N0405. | |
| Orismilast | Orismilast (LEO-32731) is an orally active and selective PDE4 inhibitor used for the research of inflammatory diseases. Orismilast demonstrates potent inhibition of PDE4B and PDE4D subtype splice variants [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LEO-32731. CAS No. 1353546-86-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117960. | |
| Oritavancin diphosphate | Oritavancin diphosphate (LY333328 diphosphate), a semisynthetic derivative of Vancomycin (HY-B0671), is an orally active glycopeptide antibiotic with bactericidal activity against gram-positive organisms. Oritavancin diphosphate shows antibacterial effect against B. anthracis , such as Ames strain with a MIC value of 0.015 g/mL. Oritavancin diphosphate inhibits cell wall synthesis and disrupts the membrane potential. Oritavancin diphosphate inhibits ArlS kinase activity thereby interfering the signal transduction. Oritavancin diphosphate enters cells by adsorptive endocytosis, which drives it to lysosomes, where it exerts antibiotic activity [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY333328 diphosphate. CAS No. 192564-14-0. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B1831A. | |
| Orlistat | Orlistat (Tetrahydrolipstatin) is a well-known irreversible inhibitor of pancreatic and gastric lipases. Orlistat is also an inhibitor of fatty acid synthase ( FASN ), is used orally for long-term research of obesity [1]. Anti-atherosclerotic effect [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Tetrahydrolipstatin; Ro-18-0647. CAS No. 96829-58-2. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg. Product ID: HY-B0218. | |
| Ormetoprim | Ormetoprim is a veterinary antimicrobial which commonly used in aquaculture and poultry industries. Ormetoprim can be used to prevent the spread of disease in freshwater aquaculture and promote growth in farm animals [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 6981-18-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-121466. | |
| Ornidazole | Ornidazole(Ro 7-0207) is a 5-nitroimidazole derivative with antiprotozoal and antibacterial properties against anaerobic bacteria. Uses: Scientific research. Group: Natural products. Alternative Names: Ro 7-0207. CAS No. 16773-42-5. Pack Sizes: 10 mM * 1 mL; 500 mg; 5 g; 10 g. Product ID: HY-B0508. | |
| Ornipressin | Ornipressin is a potent vasoconstrictor, hemostatic and renal agent. Ornipressin is also a vasopressin agonist specificly targeting to V1 receptor [1]. Uses: Scientific research. Group: Peptides. Alternative Names: POR-8. CAS No. 3397-23-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P0083. | |
| Orotic acid | Orotic acid (6-Carboxyuracil), a precursor in biosynthesis of pyrimidine nucleotides and RNA, is released from the mitochondrial dihydroorotate dehydrogenase (DHODH) for conversion to UMP by the cytoplasmic UMP synthase enzyme. Orotic acid is a marker for measurement in routine newborn screening for urea cycle disorders. Orotic acid can induce hepatic steatosis and hepatomegaly in rats [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: 6-Carboxyuracil; Vitamin B13. CAS No. 65-86-1. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-N0157. | |
| Orotic acid hydrate | Orotic acid hydrate is an endogenous metabolite. Uses: Scientific research. Group: Natural products. CAS No. 50887-69-9. Pack Sizes: 10 mM * 1 mL; 10 g; 25 g. Product ID: HY-W016812. | |
| Orotic acid potassium | Orotic acid potassium (Vitamin B13 potassium) is a precursor of pyrimidine bases and is involved in the synthesis of DNA and RNA. Orotic acid potassium stimulates the growth of animals, plants and microorganisms, participates in carbohydrate metabolism, and is necessary for the growth and life activities of organisms. Orotic acid potassium is a measurement indicator in routine newborn screening for urea cycle abnormalities. Orotic acid potassium can cause hepatic steatosis and hepatomegaly in rats [1] [2] [3] [4]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: 6-Carboxyuracil potassium; Vitamin B13 potassium. CAS No. 24598-73-0. Pack Sizes: 5 g; 10 g. Product ID: HY-N0157C. | |
| Orotic acid zinc | Orotic acid (zinc), a precursor in biosynthesis of pyrimidine nucleotides and RNA, is released from the mitochondrial dihydroorotate dehydrogenase (DHODH) for conversion to UMP by the cytoplasmic UMP synthase enzyme. Orotic acid (zinc) is a marker for measurement in routine newborn screening for urea cycle disorders. Orotic acid (zinc) can induce hepatic steatosis and hepatomegaly in rats [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: 6-Carboxyuracil zinc; Vitamin B13 zinc. CAS No. 68399-76-8. Pack Sizes: 100 mg; 500 mg. Product ID: HY-N0157A. | |
| Orotidine | Orotidine, a nucleotide, is an intermediate in pyrimidine nucleotide biosynthesis in RNA and DNA. Orotidine is mainly found in bacteria, fungi and plants [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 314-50-1. Pack Sizes: 1 mg. Product ID: HY-113226. | |
| Oroxylin A | Oroxylin A is an active flavonoid compound with strong anti-cancer effects. Oroxylin A inhibits the IL-6/STAT3 pathway and NF-κB signaling, inhibits cell proliferation and induces apoptosis. Oroxylin A inhibits colitis-related carcinogenesis [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. Alternative Names: Baicalein 6-methyl ether; 6-Methoxybaicalein. CAS No. 480-11-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N0560. | |
| Orphenadrine | Orphenadrine ((±)-Orphenadrine) is a skeletal muscle relaxant and NMDA antagonist that also has antiparkinsonian, antihistamine, antitremor, antispasmodic, and analgesic effects. Orphenadrine inhibits the binding of [3H] MK-801 to the phencyclidine (PCP) binding site of the NMDA receptor. Orphenadrine is also an anticholinergic and cytochrome P450 (CYP) 2B inducer. Orphenadrine may exert pro-tumor effects, causing CAR nuclear translocation, resulting in microsomal reactive oxygen species (ROS) production and oxidative stress. Orphenadrine also exerts neuronal protection, protecting rat cerebellar granule cells (CGC) from 3-NPA-induced death and has inhibitory potential against neurodegenerative diseases mediated by NMDA receptor overactivation [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (±)-Orphenadrine. CAS No. 83-98-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-157959. | |
| Orphenadrine citrate | Orphenadrine citrate is an orally active and non-competitive NMDA receptor antagonist (crosses the blood-brain barrier) with a K i of 6.0 μM. Orphenadrine citrate relieves stiffness, pain and discomfort due to muscle strains, sprains or other injuries. Orphenadrine citrate is also used to relieve tremors associated with parkinson's disease. Orphenadrine citrate has good neuroprotective properties, can be used in studies of neurodegenerative diseases [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 4682-36-4. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg. Product ID: HY-B0369A. | |
| Orsellinic acid | Orsellinic acid is a compound produced by Lecanoric acid treated with alcohols. Lecanoric acid is a lichen depside isolated from a Parmotrema tinctorum specimen [1]. Uses: Scientific research. Group: Natural products. CAS No. 480-64-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-N3126. | |
| Orteronel | Orteronel (TAK-700) is a highly selective inhibitor of human 17,20-lyase (CYP17) with IC 50 of 38 nM, and exhibits >1000-fold selectivity over other CYPs such as 11-hydroxylase and CYP3A4 [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TAK-700. CAS No. 566939-85-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-10505. | |
| Orticumab | Orticumab (MLDL1278A) is an antibody targeting to oxidized or malondialdehyde-modified lipoprotein (LDL). Orticumab specifically inhibits oxidized low-density lipoproteins ( oxLDL ). Orticumab involves in modulation of autoimmune responses against oxLDL, improves atherosclerosis in animal model. Orticumab also can be used for research of psoriasis improvement [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MLDL1278A. CAS No. 1314241-10-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99793. | |
| Orvepitant maleate | Orvepitant maleate (GW823296 maleate) is potent, selective, orally active and well-tolerated neurokinin-1 receptor (NK-1) antagonist with a pK i of 10.2 for human neurokinin-1 receptor. Orvepitant maleate can across the blood-brain barrier. Orvepitant maleate has the potential for depressive disorder and chronic refractory cough (CRC) treatment [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GW823296 maleate. CAS No. 579475-24-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122347A. | |
| Oryzalin | Oryzalin is a dinitroaniline herbicide, binding to plant tubulin and inhibits microtubule (MT) polymerization in vitro. Oryzalin depolymerizes MTs and prevented the polymerization of new MTs at all stages of the mitotic cycle [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 19044-88-3. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-147092. | |
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