MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Lofexidine | Lofexidine is a selective α2-receptor agonist, commonly used to alleviate the physical symptoms of heroin and other types of opioid withdrawal [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 31036-80-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-B1052A. |  |
| Lofexidine hydrochloride | Lofexidine (hydrochloride) is a selective α2-receptor agonist, commonly used to alleviate the physical symptoms of heroin and other types of opioid withdrawal [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Baq-168; MDL-14042. CAS No. 21498-08-8. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B1052. | |
| Loganin | Loganin is a type of iridoid glycoside compound that possesses anti-inflammatory, antioxidant, and antitumor properties, and offers protective effects against acute lung injury and pulmonary fibrosis. Loganin exerts its protective effects against LPS (HY-D1056)-mediated inflammation and oxidative stress by upregulating the Nrf2/HO-1 signaling pathway, and it reduces neuroinflammation caused by spinal cord injury (SCI) [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Natural products. Alternative Names: Loganoside. CAS No. 18524-94-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0512. | |
| Lokivetmab | Lokivetmab (Anti-Canine IL31 Recombinant Antibody) is an anti-canine IL-31 monoclonal antibody that can be used for the research of atopic dermatitis (AD) in dogs [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-Canine IL31 Recombinant Antibody. CAS No. 1533403-95-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99301. | |
| Lolamicin | Lolamicin is a Gram-negative specific antibiotic. Lolamicin is active against more than 130 multidrug-resistant clinical isolates, has shown efficacy in multiple mouse models of acute pneumonia and sepsis infection, and protects the gut microbiome of mice against secondary infection with Clostridium difficile. The selective killing of pathogenic gram-negative bacteria by Lolamicin is a result of the low sequence homology of pathogenic bacteria and symbiotic bacteria. Lolamicin can be used in the study of infection caused by Gram-negative pathogens [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2930690-12-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-164036. | |
| Lomefloxacin hydrochloride | Lomefloxacin (SC47111A) hydrochloride is a broad-spectrum quinolone antibiotic , with antimicrobial activity. Lomefloxacin hydrochloride is used for the research of respiratory tract infections, genitourinary infections, gastrointestinal infections, ENT infections, etc. [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SC47111A hydrochloride. CAS No. 98079-52-8. Pack Sizes: 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-B0455. | |
| Lomeguatrib | Lomeguatrib is a O6-methylguanine-DNA methyltransferase (MGMT) inhibitor, with IC50s of 9 nM in cell-free assay and ?6?nM in MCF-7 cells. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PaTrin-2. CAS No. 192441-08-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13668. | |
| Lomerizine dihydrochloride | Lomerizine dihydrochloride is an antagonist of L- and T-type voltagegated calcium channels. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KB-2796. CAS No. 101477-54-7. Pack Sizes: 10 mM * 1 mL; 10 mg; 50 mg; 100 mg. Product ID: HY-B0768A. | |
| Lometrexol | Lometrexol (DDATHF), an antipurine antifolate, can inhibit the activity of glycinamide ribonucleotide formyltransferase (GARFT) but do not induce detectable levels of DNA strand breaks. Lometrexol can further inhibit de novo purine synthesis, causing abnormal cell proliferation and apoptosis, even cell cycle arrest. Lometrexol has anticancer activity. Lometrexol also is a potent human Serine hydroxymethyltransferase1/2 (hSHMT1/2) inhibitor[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DDATHF. CAS No. 106400-81-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14521. | |
| Lomifylline | Lomifylline is a derivative of Xanthine (HY-W017389). Lomifylline can be used in research of sepsis and septic or endotoxic shock, when combined with an antibody to TNF or a TNF binding fragment [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 10226-54-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-114531. | |
| Lomitapide | Lomitapide (AEGR-733; BMS-201038) is a potent inhibitor of microsomal triglyceride-transfer protein ( MTP ) with an IC 50 of 8 nM in vitro. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AEGR-733; BMS-201038. CAS No. 182431-12-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-14667. | |
| Lomitapide mesylate | Lomitapide mesylate(AEGR-733; BMS-201038) is an inhibitor of microsomal triglyceride-transfer protein (MTP) wtih in vitro IC50 of 8 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AEGR-733 mesylate; BMS-201038 mesylate. CAS No. 202914-84-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-14668. | |
| Lomustine | Lomustine (CCNU; NSC 79037) is a DNA alkylating agent, with antitumor activity. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CCNU; NSC 79037. CAS No. 13010-47-4. Pack Sizes: 10 mM * 1 mL; 200 mg; 500 mg. Product ID: HY-13669. | |
| Lonafarnib | Lonafarnib (Sch66336) is a potent and orally active farnesyl transferase (FTase) inhibitor. Lonafarnib inhibits the activities of H-ras , K-ras and N-ras with IC 50 values of 1.9 nM, 5.2 nM and 2.8 nM, respectively. Lonafarnib also has anti-hepatitis delta virus (HDV) activities. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Sch66336. CAS No. 193275-84-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15136. | |
| Lonazolac | Lonazolac is a non-steroidal antirheumatic agent. Anti-inflammatory effects [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 53808-88-1. Pack Sizes: 10 mM * 1 mL; 5 mg. Product ID: HY-W173309. | |
| Loncastuximab | Loncastuximab (RB4v1.2) is an anti- CD19 monoclonal antibody. Loncastuximab shows antitumor activity and has potential application in non-Hodgkin's lymphoma (NHL), including diffuse large B-cell lymphoma (DLBCL) [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: RB4v1.2. CAS No. 1875032-68-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99711. | |
| Loncastuximab tesirine | Loncastuximab tesirine is a human cluster of differentiation 19 ( CD19 )-directed antibody-drug conjugate (ADC). Once bound to CD19 on the cell membrane, loncastuximab tesirine is rapidly internalised and triggers cell death. Loncastuximab tesirin induces cell apoptosis , it can be used for the research of diffuse large B-cell lymphoma [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Loncastuximab tesirine-lpyl; ADCT-402. CAS No. 1879918-31-6. Pack Sizes: 100 μg; 200 μg; 500 μg; 1 mg. Product ID: HY-P99349. | |
| (+)-Longifolene | (+)-Longifolene is a sesquiterpenoid and a metabolite in rabbits. (+)-Longifolen is converted to primary, secondary or tertiary alcohols in rabbits, among which the primary alcohol is predominant [1]. Uses: Scientific research. Group: Natural products. CAS No. 475-20-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-N6662. | |
| Lonidamine | Lonidamine (AF-1890) is a hexokinase and mitochondrial pyruvate carrier inhibitor ( K i : 2.5 μM). Lonidamine also inhibits aerobic glycolysis in cancer cells. Lonidamine can be used in the research of mitochondrial metabolism and inflammation, such as pulmonary fibrosis [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AF-1890; Diclondazolic Acid; DICA. CAS No. 50264-69-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-B0486. | |
| Lonigutamab | Lonigutamab (hz208F2-4) is a humanized anti- IGF-1R monoclonal antibody that can be used for the synthesis of antibody - agent conjugates (ADC) [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: hz208F2-4. CAS No. 2362015-67-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99712. | |
| Lonodelestat | Lonodelestat (POL6014) is a potent, orally active and selective peptide inhibitor of human neutrophil elastase (hNE). Lonodelestat (POL6014) has the potential for the research of cystic fibrosis (CF) [1] [2] [3]. Uses: Scientific research. Group: Peptides. Alternative Names: POL6014. CAS No. 906547-89-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P3293. | |
| LONP1-IN-2 | LONP1-IN-2 (Compound 9e) is a potent and selective LONP1 inhibitor with an IC50 value of 0.093 ?M. LONP1-IN-2 can be used in research of cancer[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2729981-17-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-153034. | |
| Loperamide-d6 hydrochloride | Loperamide-d 6 (hydrochloride) is a deuterium labeled Loperamide hydrochloride. Loperamide hydrochloride is an opioid receptor agonist for the treatment of diarrhea[1]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: R-18553-d6 hydrochloride. CAS No. 1189469-46-2. Pack Sizes: 1 mg. Product ID: HY-B0418AS. | |
| Loperamide hydrochloride | Loperamide (hydrochloride) (R-18553 (hydrochloride)) is an opioid receptor agonist [1] [2] [3]. Loperamide hydrochloride is a selective and competitive human intestinal carboxylesterases (hiCE) inhibitor. Loperamide hydrochloride has anti-diarrheal effect [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R-18553 hydrochloride. CAS No. 34552-83-5. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0418A. | |
| Loperamide (hydrochloride) (Standard) | Loperamide (hydrochloride) (Standard) is the analytical standard of Loperamide (hydrochloride). This product is intended for research and analytical applications. Loperamide (hydrochloride) (R-18553 (hydrochloride)) is an opioid receptor agonist [1] [2] [3]. Loperamide hydrochloride is a selective and competitive human intestinal carboxylesterases (hiCE) inhibitor. Loperamide hydrochloride has anti-diarrheal effect [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R-18553 (hydrochloride) (Standard). CAS No. 34552-83-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0418AR. | |
| Lopinavir | Lopinavir (ABT-378) is a highly potent, selective peptidomimetic inhibitor of the HIV-1 protease , with K i s of 1.3 to 3.6 pM for wild-type and mutant HIV protease. Lopinavir acts by arresting maturation of HIV-1 thereby blocking its infectivity [1] [2]. Lopinavir is also a SARS-CoV 3CL pro inhibitor with an IC 50 of 14.2 μM [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABT-378. CAS No. 192725-17-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 250 mg. Product ID: HY-14588. | |
| Loracarbef hydrate | Loracarbef hydrate, a cephalosporin antibiotic , is an orally active second-generation synthetic beta-lactam antibiotic of the carbacephem class [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 121961-22-6. Pack Sizes: 1 mg. Product ID: HY-B1682A. | |
| Loratadine | Loratadine (SCH-29851) is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM. Loratadine has anti- dengue-virus (DENV) activity. Loratadine can inhibit immunologic release of inflammatory mediators. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Loratidine; SCH 29851. CAS No. 79794-75-5. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg. Product ID: HY-17043. | |
| Lorediplon | Lorediplon is a novel non-benzodiazepine drug acting as a GABAA receptor modulator, differentially active at the alpha1-subunit, associated with promoting sleep. Uses: Scientific research. Group: Signaling pathways. CAS No. 917393-39-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-19371. | |
| Lorlatinib | Lorlatinib (PF-06463922) is a selective, orally active, brain-penetrant and ATP-competitive ROS1/ALK inhibitor with anticancer activity. Lorlatinib has K i s of <0.025 nM, <0.07 nM, and 0.7 nM for ROS1, wild type ALK, and ALK L1196M , respectively. Lorlatinib targets to EML4-ALK, and inhibits ALK phosphorylation with IC 50 s of 15-43 nM (ALK L1196 ), 14-80 nM (ALK G1269A ), 38-50 nM (ALK 1151Tins ), 77-113 nM (ALK G1202R ), respectively [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PF-06463922. CAS No. 1454846-35-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12215. | |
| L-Ornithine | L-Ornithine ((S)-2,5-Diaminopentanoic acid) is a non-proteinogenic amino acid, is mainly used in urea cycle removing excess nitrogen in vivo. L-Ornithine shows nephroprotective [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: (S)-2,5-Diaminopentanoic acid. CAS No. 70-26-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B1352. | |
| L-Ornithine-1,2,3,4,5-13C5 hydrochloride | L-Ornithine-1,2,3,4,5-13C5 (hydrochloride) is the 13C-labeled L-Ornithine hydrochloride. L-Ornithine hydrochloride is a free amino acid that plays a central role in the urea cycle and is also important for the disposal of excess nitrogen. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 943962-21-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-W017018S2. | |
| L-Ornithine hydrochloride | L-Ornithine hydrochloride is a non-proteinogenic amino acid, is mainly used in urea cycle removing excess nitrogen in vivo. L-Ornithine hydrochloride shows nephroprotective [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 3184-13-2. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-W017018. | |
| L-Ornithine L-aspartate | L-Ornithine L-aspartate is a stable salt of two natural nonessential L-amino acids with oral activity: ornithine and aspartic acid. L-Ornithine L-aspartate lowers blood ammonia concentration and to eliminate symptoms of hepatic encephalopathy associated with liver cirrhosis. L-Ornithine L-aspartate also improves mitochondrial functions [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3230-94-2. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-A0282. | |
| Lornoxicam | Lornoxicam (Chlortenoxicam) is an orally active oxycontin nonsteroidal anti-inflammatory drug (NSAID) with analgesic, anti-inflammatory, antipyretic and anticancer activities. Lornoxicam exhibits good inhibitory effects on both COX-1 and COX-2 ( COX-1 : IC 50 =0.005 μM; COX-2 : IC 50 =0.008 μM) and inhibits the production of NO by iNOS ( IC 50 =65 μM) and the proinflammatory cytokine IL-6 ( IC 50 =54 μM). Lornoxicam also inhibits tumor cell proliferation and migration and induces tumor cell apoptosis. Lornoxicam can be used in the study of inflammatory pain, colorectal cancer and breast cancer [1] [2] [3] [4] [5] [6] [7]. Uses: Scientific research. Group: Natural products. Alternative Names: Chlortenoxicam; Ro 13-9297. CAS No. 70374-39-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg. Product ID: HY-B0367. | |
| Lorundrostat | Lorundrostat (MT-4129) is an orally active aldosterone synthase inhibitor. Lorundrostat can be used in studies of high blood pressure [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MT-4129. CAS No. 1820940-17-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147277. | |
| Lorvotuzumab | Lorvotuzumab (Anti-NCAM1/CD56 Reference Antibody (lorvotuzumab)) is a humanized monoclonal antibody that binds CD56 (NCAM1). Lorvotuzumab can be used to synthesize an ADC compound, Lorvotuzumab mertansine [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-NCAM1/ CD56 Reference Antibody (lorvotuzumab). CAS No. 339306-30-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99372. | |
| Losartan | Losartan is an angiotensin II receptor antagonist, competing with the binding of angiotensin II to AT1 receptors with IC 50 of 20 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DuP-753. CAS No. 114798-26-4. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-17512. | |
| Losartan Carboxylic Acid | Losartan Carboxylic Acid (E-3174), an active carboxylic acid metabolite of Losartan, is an angiotensin II receptor type 1 (AT1) antagonist. The Ki values are 0.97, 0.57, 0.67 nM for rat AT1B/AT1A and human AT1, respectively. Losartan Carboxylic Acid blocks the angiotensin II-induced responses in vascular smoothmuscle cells (VSMC). Losartan Carboxylic Acid elevates plasma renin activities and reduces mean arterial pressure[1][2][3][4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: E-3174; EXP-3174. CAS No. 124750-92-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-12765. | |
| Losartan potassium | Losartan potassium (DuP-753 potassium) is an angiotensin II receptor type 1 (AT1) antagonist, competing with the binding of angiotensin II to AT1 with an IC 50 of 20 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DuP-753 potassium. CAS No. 124750-99-8. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-17512A. | |
| Losartan (potassium) (Standard) | Losartan (potassium) (Standard) is the analytical standard of Losartan (potassium). This product is intended for research and analytical applications. Losartan potassium (DuP-753 potassium) is an angiotensin II receptor type 1 (AT1) antagonist, competing with the binding of angiotensin II to AT1 with an IC 50 of 20 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DuP-753 (potassium) (Standard). CAS No. 124750-99-8. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-17512AR. | |
| Losatuxizumab | Losatuxizumab (ABT-806) is an anti- EGFR monoclonal antibody. Losatuxizumab binds to EGFR with EC 50 s of 0.96 nM for EGFR wild-type, 0.09 nM for EGFR C271A,C283A , 0.12 nM for EGFRvIII, 0.66 nM for EGFR1-501. Losatuxizumab can be used for research of EGFR-expressing cancers [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ABT-806. CAS No. 1801544-27-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99715. | |
| Losigamone | Losigamone (AO-33) is an orally active antiepileptic compound. Losigamone blocks sodium channel. Losigamone stimulates the neuronal chloride channel and enhance chloride influx. Losigamone potentiates GABA-mediated responses and reduces epileptiform activity induced by chloride channel antagonists. Losigamone can be used for epilepsy research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AO-33; (±)-Losigamone; LSG. CAS No. 112856-44-7. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-106822. | |
| Losmapimod | Losmapimod (GSK-AHAB) is a selective, potent, and orally active p38 MAPK inhibitor with pK i s of 8.1 and 7.6 for p38α and p38β, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GSK-AHAB; GW856553X; SB856553. CAS No. 585543-15-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-10402. | |
| Lotaustralin | Lotaustralin is a cyanogenic glucoside isolated from Manihot esculenta [1]. Uses: Scientific research. Group: Natural products. CAS No. 1973415-50-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N5079. | |
| Loteprednol Etabonate | Loteprednol etabonate (LE) is an orally active "soft" steroid belonging to a unique class of glucocorticoids. Loteprednol etabonate (LE) exhibits anti-inflammatory activity and has been used in optometry and ophthalmology [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 82034-46-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17358. | |
| Lotiglipron | Lotiglipron (PF-07081532) is an orally active GLP-1R agonist. Lotiglipron reduces glucose and body weight, and can be used for research of Type 2 diabetes mellitus (T2DM) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PF-07081532. CAS No. 2401892-75-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153865. | |
| Lotilaner | Lotilaner is a parasiticide , acts as a potent non-competitive antagonist of insects GABACl receptors , with an IC 50 of 23.84 nM for Drosophila melanogaster GABA receptor. No effect on a dog GABAA receptor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1369852-71-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116564. | |
| Lovastatin | Lovastatin is a cell-permeable HMG-CoA reductase inhibitor used to lower cholesterol. Uses: Scientific research. Group: Natural products. Alternative Names: Mevinolin. CAS No. 75330-75-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0504. | |
| Loviride | Loviride (R 89439) is a non-nucleoside reverse transcriptase inhibitor ( NNRTI ), with an IC 50 of 0.3 μM for reverse transcriptase from HIV-1. Loviride (R 89439) inhibits HIV-1, HIV-2 and SIV replication in MT-4 cells [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R 89439. CAS No. 147362-57-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15355. | |
| Low molecular weight protamine | Low molecular weight protamine is a cell-penetrating peptide with vascular endothelial growth factor ( VEGF ) inhibitory activity. Low molecular weight protamine can inhibit tumor growth and is used in cancer research [1]. Uses: Scientific research. Group: Peptides. Alternative Names: LMWP. CAS No. 121052-30-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P5107. | |
| Loxapine | Loxapine is an orally active dopamine inhibitor, 5-HT receptor antagonist and also a dibenzoxazepine anti-psychotic agent [1] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1977-10-2. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-17390. | |
| Loxapine succinate | Loxapine succinate is an orally active dopamine inhibitor, 5-HT receptor antagonist and also a dibenzoxazepine anti-psychotic agent. Loxapine can also suppresses bacterial efflux pump activity and inhibit intracellular multiple-antibiotic-resistant Salmonella enterica serovar Typhimurium in macrophages [1] [4] [6]. Uses: Scientific research. Group: Signaling pathways. CAS No. 27833-64-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-17390A. | |
| Loxiglumide | Loxiglumide is a cholecystokinin ( CCK-1 ) receptor antagonist. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CR-1505. CAS No. 107097-80-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B2154. | |
| Loxoprofen | Loxoprofen is a non-steroidal, orally active anti-inflammatory agent with analgesic and anti-pyretic properties. Loxoprofen is a nonselective COX inhibitor with IC 50 s of 6.5 and 13.5 μM for COX-1 and COX-2, respectively. Loxoprofen can reduce atherosclerosis and shows antitumor activity [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 68767-14-6. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-B0578. | |
| Loxoprofen sodium | Loxoprofen sodium is a non-steroidal, orally active anti-inflammatory agent with analgesic and anti-pyretic properties. Loxoprofen sodium is a nonselective COX inhibitor with IC 50 s of 6.5 and 13.5 μM for COX-1 and COX-2, respectively. Loxoprofen sodium can reduce atherosclerosis and shows antitumor activity [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 80382-23-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-B0578A. | |
| LP17 | LP17 (LQVTDSGLYRCVIYHPP) is a BBB-penetrable triggering receptor expressed on myeloid cells (TREM-1) inhibitory peptide. LP17 substantially alleviates ischemia-induced infarction and neuronal injury. LP17 can get access into brain and block TREM-1[1]. Uses: Scientific research. Group: Peptides. Alternative Names: LQVTDSGLYRCVIYHPP. CAS No. 887255-16-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P3400. | |
| LP-184 | LP-184 (compound 6), an acylfulvene analog, inhibits tumor growth. LP-184 has potent anti-cancer activity in the ovarian, colon, prostate and pancreatic cell lines. (patent WO2007019308A2). Uses: Scientific research. Group: Signaling pathways. CAS No. 924835-67-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-139453. | |
| LP-922056 | LP-922056 is an orally active, highly potent Notum Pectinacetylesterase inhibitor with EC50s of 21 nM, 55 nM in human and mouse cellular assay, respectively. LP-922056 significantly increases midshaft femur cortical bone thickness in mice and rats[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1365060-22-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-131034. | |
| LP-935509 | LP-935509 is an orally active, potent, selective, ATP-competitive and brain-penetrant inhibitor of adaptor protein-2 associated kinase 1 (AAK1) with an IC50 of 3.3 nM and a Ki of 0.9 nM, respectively. LP-935509 is also a potent inhibitor of BIKE (IC50=14 nM) and a modest inhibitor of GAK (IC50=320 nM). LP-935509 shows antinociceptive activity. LP-935509 can be used for neuropathic pain and SARS-CoV-2 research[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1454555-29-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-117626. | |
| LP99 | LP99, an epigenetic probe, is a potent and selective inhibitor of the BRD7 and BRD9 bromodomains with a K d of 99 nM against BRD9. LP99 disrupts the binding of BRD7 and BRD9 to chromatin in cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1808951-93-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19553. | |
| LPA1 receptor antagonist 1 | LPA1 receptor antagonist 1 is a highly selective Lysophosphatidic Acid receptor-1 (LPA1) antagonist with an IC 50 of 25 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1396006-71-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-18076. | |
| LPA2 antagonist 1 | LPA2 antagonist 1 is a LPA2 antagonist with an IC50 of 17 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1017606-66-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18075. | |
| L-Palmitoylcarnitine | L-Palmitoylcarnitine, a long-chain acylcarnitine and a fatty acid metabolite, accumulates in the sarcolemma and deranges the membrane lipid environment during ischaemia. L-Palmitoylcarnitine inhibits K ATP channel activity, without affecting the single channel conductance, through interaction with Kir6.2 [1]. Uses: Scientific research. Group: Natural products. CAS No. 2364-67-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-113147. | |
| L-Palmitoylcarnitine chloride | L-Palmitoylcarnitine chloride, a long-chain acylcarnitine and a fatty acid metabolite, accumulates in the sarcolemma and deranges the membrane lipid environment during ischaemia. L-Palmitoylcarnitine chloride inhibits K ATP channel activity, without affecting the single channel conductance, through interaction with Kir6.2 [1]. Uses: Scientific research. Group: Natural products. CAS No. 18877-64-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113147A. | |
| L-p-Boronophenylalanine | L-p-Boronophenylalanine is a boron-containing substrate for L-type amino acid transporters (LAT1 and LAT2). L-p-Boronophenylalanine enters tumor cells by competing with natural amino acids for LAT, selectively accumulating boron in cancer cells. L-p-Boronophenylalanine can be used in boron neutron capture therapy (BNCT). When boron-10 captures thermal neutrons, a nuclear reaction occurs, producing high-energy alpha particles and lithium nuclei, which kill cancer cells at close range with little damage to surrounding tissues. L-p-Boronophenylalanine can be used in cancer research, especially glioblastoma and anaplastic astrocytoma[1][2]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 76410-58-7. Pack Sizes: 250 mg; 1 g. Product ID: HY-W087830. | |
| L-Perillaldehyde | L-Perillaldehyde is a major component in the essential oil containing in Perillae Herba. Inhalation of L-Perillaldehyde shows antidepressant-like activity through the olfactory nervous function [1]. Uses: Scientific research. Group: Natural products. Alternative Names: (S)-(-)-Perillaldehyde; (S)-Perillaldehyde. CAS No. 18031-40-8. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-N2085. | |
| L-Phenylalanine | L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca + channels antagonist with a K i of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) ( K B of 573 μM ) and non-NMDARs , respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Phenylalanine. CAS No. 63-91-2. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g; 10 g. Product ID: HY-N0215. | |
| L-Phenylalanine-13C | L-Phenylalanine- 13 C is the 13 C-labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: (S)-2-Amino-3-phenylpropionic acid- 13 C. CAS No. 81201-86-7. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-N0215S2. | |
| L-Phenylalanine-13C9,15N | L-Phenylalanine- 13 C 9 , 15 N is the 13 C- and 15 N-labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM ) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: (S)-2-Amino-3-phenylpropionic acid- 13 C9, 15 N. CAS No. 878339-23-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N0215S11. | |
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