MedChemExpress MCE - Products

MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.

Product
M-31850 M-31850 is a potent, selective and competitive ?-hexosaminidase (Hex) inhibitor with IC50s of 6.0 ?M and 3.1 ?M for human HexA and human HexB, respectively. M-31850 also competitively inhibits ?-N-acetyl-D-hexosaminidase OfHex2 with a Ki of 2.5 ?M[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 281224-40-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-104050. MedChemExpress MCE
M3258 M3258 is an orally bioavailable, potent, reversible and highly selective immunoproteasome subunit LMP7 (?5i) inhibitor. M3258 exerts high biochemical (IC50=3.6 nM) and cellular (IC50=3.4 nM) potency against the LMP7 subunit. M3258 shows strong antitumor efficacy in multiple myeloma xenograft models. M3258 leads to a significant and prolonged suppression of tumor LMP7 activity and ubiquitinated protein turnover and the induction of apoptosis in multiple myeloma cells[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2285330-15-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-111790. MedChemExpress MCE
M344 M344 (D 237) is an inhibitor of histone deacetylase ( IC 50 =100 nM) and an inducer of terminal cell fifferentiation. Uses: Scientific research. Group: Signaling pathways. Alternative Names: D 237; MS 344. CAS No. 251456-60-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-13506. MedChemExpress MCE
m-3M3FBS m-3M3FBS is a potent phospholipase C (PLC) activator. m-3M3FBS stimulates superoxide generation in human neutrophils, upregulates intracellular calcium concentration, and stimulates inositol phosphate generation in various cell lines. m-3M3FBS induces monocytic leukemia cell apoptosis[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 200933-14-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19619. MedChemExpress MCE
M443 M443 is an irreversible and specific inhibitor of MRK, with an IC50<125 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1820684-31-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112274. MedChemExpress MCE
M47 M47 is a small molecule that selectively destabilizes Cryptochrome 1 (CRY1) and increases degradation of the CRY1 in the nucleus. M47 enhances apoptosis in Ras-transformed P53-deficient mouse skin fibroblast lines and enhances life span in p53 knockout mice. M47 can be used in research of cancer [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 890808-56-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148764. MedChemExpress MCE
M617 M617 is a selective galanin receptor 1 (GAL1) agonist, with K i s of 0.23 and 5.71 nM for GAL1 and GAL2, respectively. M617, acting through its central GAL1, can promote GLUT4 expression and enhance GLUT4 content in the cardiac muscle of type 2 diabetic rats [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 860790-38-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1131. MedChemExpress MCE
M65 TFA M65 TFA is a deleted peptide of maxadilan (61 a.a.) with deletion of the residues between positions 24 and 42 and is a specific antagonist of PACAP type 1 receptor that inhibits ANP secretion and can be used for relevant researches[1][2]. Uses: Scientific research. Group: Peptides. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P4127A. MedChemExpress MCE
m7GpppAmpG ammonium m7GpppAmpG ammonium (m7G(5')ppp(5')(2'OMeA)pG ammonium) is a trinucleotide 5? end cap analog. m7GpppAmpG ammonium binds to eIF4E with a KD value of 45.6 nM. m7GpppAmpG ammonium caps RNA with a capping efficiency of 90%. m7GpppAmpG ammonium enhances mRNA stability and translation efficiency. m7GpppAmpG ammonium is used in mRNA therapeutic research[1][2][3]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: m7G(5')ppp(5')(2'OMeA)pG ammonium. Pack Sizes: 1.1 mg (100 mM * 10 ?L in Water); 5.7 mg (100 mM * 50 ?L in Water); 11.5 mg (100 mM * 100 ?L in Water). Product ID: HY-145974A. MedChemExpress MCE
M871 M871 (Galanin-(2-13)-Glu-His-(Pro)3-(Ala-Leu)2-Ala-amide) is a selective galanin receptor type 2 ( GalR2 ) antagonist. M871 exhibits K i values of 13.1 nM and 420 nM for GalR2 and GalR1 , respectively. M871 can be used for research on GalR2 -related diseases (such as epilepsy, pain) [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Galanin-(2-13)-Glu-His-(Pro)3-(Ala-Leu)2-Ala-amide. CAS No. 908844-75-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1130. MedChemExpress MCE
M-89 M-89 is a highly potent and specific menin inhibitor, with a K d of 1.4 nM for binding to menin. M-89 inhibits the menin-mixed lineage leukemia (Menin-MLL) protein-protein interaction and has potential to treat MLL leukemia [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2363165-42-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128347. MedChemExpress MCE
Maackiain Maackiain (DL-Maackiain) is isolated from Maackia amurensis Rupr.et Maxim. Maackiain (DL-Maackiain) is a larvicidal agent against Aedes aegypti mosquito.xp Parasitol with a LD 50 of ?21.95 μg/mL [1]. Maackiain (DL-Maackiain) induces fragmentations of DNA to oligonucleosomal-sized fragments that like a characteristic of apoptosis in the HL-60 cells [2]. Uses: Scientific research. Group: Natural products. Alternative Names: DL-Maackiain. CAS No. 19908-48-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N0381. MedChemExpress MCE
Mabuterol Mabuterol is a selective and orally active beta-2 adrenergic receptor (ADRB2) agonist. Mabuterol inhibits the proliferation and suppresses the increase of intracellular Ca2+ induced by PDGF-BB. Mabuterol suppresses the protein expressions of Drp-1, cyclinD1 and PCNA and enhanced the expression of Mfn-2 induced by PDGF-BB [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 56341-08-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13338. MedChemExpress MCE
Macamide B Macamide B (N-Benzylhexadecanamide; Macamide 1) is a macamide isolated from Lepidium meyenii , acts as an inhibitor of fatty acid amide hydrolase (FAAH). Uses: Scientific research. Group: Natural products. Alternative Names: N-Benzylpalmitamide; N-Benzylhexadecanamide; Macamide 1. CAS No. 74058-71-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N2365. MedChemExpress MCE
Macelignan Macelignan ((+)-Anwulignan; Anwuligan) is an orally active lignan isolated from Myristica fragrans. Macelignan possesses many pharmacological activities, including anti-inflammatory, anti-cancer, anti-diabetes, and neuroprotective activities [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: (+)-Anwulignan; Anwuligan. CAS No. 107534-93-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0064. MedChemExpress MCE
MAC glucuronide linker-1 MAC glucuronide linker-1 is a claevable ADC linker for antibody-agent-conjugations (ADCs)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2222981-71-5. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-44221. MedChemExpress MCE
Macimorelin acetate Macimorelin (EP-1572) acetate, a GH secretagogue, is an orally active GHSR agonist. Macimorelin acetate stimulates GH release. Macimorelin acetate can be used in the research of adult growth hormone deficiency (AGHD), and Cancer anorexia-cachexia syndrome (CACS) [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EP-1572 acetate; AEZS-130 acetate. CAS No. 945212-59-9. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-14820A. MedChemExpress MCE
Macitentan Macitentan (ACT-064992) is an orally active, non-peptide dual ETA and ETB (endothelin receptor) antagonist. Macitentan has the potential for idiopathic pulmonary fibrosis (IPF) and pulmonary arterial hypertension (PAH) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ACT-064992. CAS No. 441798-33-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14184. MedChemExpress MCE
Macropa Macropa is a macrocyclic chelator that can be used as radionuclides to study soft tissue metastases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1128304-86-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-160131. MedChemExpress MCE
Madecassic acid Madecassic acid is isolated from Centella asiatica (Umbelliferae). Madecassic acid has anti-inflammatory properties caused by iNOS , COX-2 , TNF-alpha , IL-1beta , and IL-6 inhibition via the downregulation of NF-κB activation in RAW 264.7 macrophage cells [1]. Uses: Scientific research. Group: Natural products. CAS No. 18449-41-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 20 mg. Product ID: HY-N0569. MedChemExpress MCE
Madecassoside Madecassoside is a pentacyclic triterpene isolated from Centella asiatica and has anti-inflammatory properties. Antioxidant and anti-aging effects. Madecassoside is a pentacyclic triterpene isolated from Centella asiatica. Madecassoside is orally active and has inhibitory properties against inflammation, oxidation, apoptosis and autophagy. Madecassosid inhibits activities of p38 MAPK and NF-kB [5][6] , exhibits an anti-apopototic property, activates Nrf2 expression to reduce the neurotoxicity [10]. Madecassoside can be used in endocrine diseases, cardiovascular diseases, skin diseases and other diseases. Uses: Scientific research. Group: Natural products. Alternative Names: Asiaticoside A. CAS No. 34540-22-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-N0568. MedChemExpress MCE
Madrasin Madrasin (DDD00107587) is a splicing inhibitor that prevents formation of both splicing intermediates and products in vitro and interferes with one or more early steps in the pathway of spliceosome assembly. Madrasin also can inhibit pre-mRNA splicing in vitro and modify splicing of endogenous pre-mRNA in cells[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DDD00107587. CAS No. 374913-63-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100236. MedChemExpress MCE
Maduramicin ammonium Maduramicin (Maduramycin) ammonium is isolated from the actinomycete Actinomadura rubra. Maduramicin ammonium is an oral active anticoccidial agent used in research related to Eimeria, Adenosarcina, Enterococcus faecalis, and Enterococcus disperitus infections. Maduramicin ammonium induces apoptosis ( apoptosis ) in chicken cardiomyocytes through both intrinsic and extrinsic pathways and also impairs autophagic flux and induces rhabdomyolysis by activating the AMPK -mediated eIF2α-ATF4 endoplasmic reticulum stress pathway [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Maduramycin ammonium. CAS No. 84878-61-5. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N7071A. MedChemExpress MCE
Mafenide Acetate Mafenide Acetate is an effective sulfonamide-type antimicrobial agent used for burn wounds. Mafenide Acetate shows activity against both Gram-positive and Gram-negative organisms , including Pseudomonas aeruginosa , via inhibition of nucleotide synthesis [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 13009-99-9. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-B0614A. MedChemExpress MCE
Mafenide hydrochloride Mafenide hydrochloride is an effective sulfonamide-type antimicrobial agent used for burn wounds. Mafenide hydrochloride shows activity against both Gram-positive and Gram-negative organisms , including Pseudomonas aeruginosa , via inhibition of nucleotide synthesis [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 138-37-4. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B0614B. MedChemExpress MCE
MAFP MAFP (Methyl Arachidonyl Fluorophosphonate) is an selective, active-site directed and irreversible inhibitor of cPLA2 and iPLA2. MAFP is also a potent irreversible inhibitor of anandamide amidase. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Methyl Arachidonyl Fluorophosphonate. CAS No. 188404-10-6. Pack Sizes: 1 mg (26.99 mM * 100 μL in Methyl acetate). Product ID: HY-103334. MedChemExpress MCE
Maftivimab Maftivimab (REGN3470-3471-3479), the inhibitor of Filovirus , is an Food and agent Administration (FDA)-approved agent. Maftivimab, also named as Atoltivimab, Odesivimab (Inmazeb), can be used for research of Zaire ebolavirus infection [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: REGN3470-3471-3479. CAS No. 2135632-36-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99722. MedChemExpress MCE
Magnesium acetate tetrahydrate Magnesium acetate tetrahydrate is a hydrated form of anhydrous magnesium acetate salt. As a salt form of Magnesium, Magnesium acetate tetrahydrate is one of the bioavailable forms of magnesium and forms a very water soluble compound. Magnesium acetate tetrahydrate can be used as an electrolyte supplementation or a reagent in molecular biology experiments [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 16674-78-5. Pack Sizes: 50 g; 100 g. Product ID: HY-Y0319G. MedChemExpress MCE
Magnesium chloride hexahydrate, for molecular biology Magnesium chloride hexahydrate (MgCl2 hexahydrate), for molecular biology is the hexahydrate form of magnesium dichloride. Magnesium chloride hexahydrate can be used as a source of magnesium ion and a co-foactor for many enzymes. Magnesium chloride hexahydrate increases the activity of Ca 2+ ATPase [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: MgCl2 hexahydrate, for molecular biology. CAS No. 7791-18-6. Pack Sizes: 10 g; 25 g. Product ID: HY-W019981B. MedChemExpress MCE
Magnesium citrate Magnesium citrate is a magnesium salt form that provides efficient penetration into brain and muscle tissue. Magnesium citrate increases pain threshold and reduces TLR4 concentration in the brain. Orally active [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Trimagnesium dicitrate. CAS No. 3344-18-1. Pack Sizes: 100 mg; 500 mg. Product ID: HY-W105835. MedChemExpress MCE
Magnesium glycinate Magnesium glycinate (Magnesium bisglycinate), the magnesium salt of glycine, is a nutrient supplement. Magnesium glycinate has satisfactory physico-chemical properties and bioactivities. Metal glycinate chelates are formed by glycine and metal compounds through chemical reactions. Magnesium is an essential mineral that plays a critical role in the human body. Magnesium takes part in the process of energy metabolism and assists the maintenance of normal muscle function [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Magnesium bisglycinate; Magnesium diglycinate. CAS No. 14783-68-7. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g; 10 g. Product ID: HY-129328. MedChemExpress MCE
Magnesium isoglycyrrhizinate hydrate Magnesium isoglycyrrhizinate hydrate is the active component found in licorice plant ( Glycyrrhiza glabra ). Magnesium isoglycyrrhizinate hydrate exhibits anti-inflammatory activity through NLRP3 inflammasome pathway, and attenuates the chronic obstructive pulmonary disease in rats [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 658701-67-8. Pack Sizes: 5 mg. Product ID: HY-154795. MedChemExpress MCE
Magnesium Lithospermate B Magnesium Lithospermate B, is a derivative of caffeic acid tetramer and an inhibitor of Na+/K+ ATPase , which can be extracted from Salviae miltiorrhizae. Magnesium Lithospermate B is widely used for the research of cardiovascular diseases, and it can protect against glucose-induced intracellular oxidative damage. Magnesium Lithospermate B also suppresses neuroin ammation and attenuates neurodegeneration [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 122021-74-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126415. MedChemExpress MCE
Magnesium silicate Magnesium silicate (Activated magnesium silicate) is an orally active compound composed of magnesium oxide (MgO) and silicon dioxide (SiO2). Magnesium silicate can be used in the preparation of food additives, antacids and anti-ulcer agents. Magnesium silicate is also a piezoelectric biomaterial, deodorant, decolorizing agent and antifungal agent [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Activated magnesium silicate. CAS No. 1343-88-0. Pack Sizes: 5 g. Product ID: HY-B2205. MedChemExpress MCE
Magnesium sulfate Magnesium sulphate is currently the anticonvulsant of choice for the prevention and control of eclamptic fits. Magnesium sulfate is also widely used as a tocolytic agent [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 7487-88-9. Pack Sizes: 50 g. Product ID: HY-Y1267. MedChemExpress MCE
(+)-Magnoflorine chloride Magnoflorine chloride (Magnoflorine chloride), an aporphine alkaloid found in Magnolia or Aristolochia, reduces the formation of C. albicans biofilm [1]. Magnoflorine chloride has anti-fungal, anti-antidiabetic and anti-oxidative activity [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Magnoflorine chloride; α-Magnoflorine chloride; Thalictrine chloride. CAS No. 6681-18-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N0535. MedChemExpress MCE
(+)-Magnoflorine iodide (+)-Magnoflorine iodide (Magnoflorine iodide), an aporphine alkaloid found in Acoruscalamus , reduces the formation of C. albicans biofilm [1]. (+)-Magnoflorine iodide has anti-fungal, anti-antidiabetic and anti-oxidative activity [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Magnoflorine iodide; α-Magnoflorine iodide; Thalictrine iodide. CAS No. 4277-43-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 20 mg. Product ID: HY-N0334A. MedChemExpress MCE
Magnolol Magnolol, a natural lignan isolated from the stem bark of Magnolia officinalis , is a dual agonist of both RXRα and PPARγ , with EC 50 values of 10.4 μM and 17.7 μM, respectively. Uses: Scientific research. Group: Natural products. CAS No. 528-43-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0163. MedChemExpress MCE
Magrolimab Magrolimab (Hu5F9-G4) is a humanized anti- CD47 antibody. Magrolimab can block the "don't eat me" signal of CD47 , thereby promoting macrophage mediated phagocytosis. Magrolimab has antitumor activity in malignant bone tumors and breast cancer [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Hu5F9-G4. CAS No. 2169232-81-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99029. MedChemExpress MCE
MAHMA NONOate MAHMA NONOate is a NO donor. MAHMA NONOate effectively inhibits platelet aggregation induced by either collagen or ADP [1]. Uses: Scientific research. Group: Natural products. CAS No. 146724-86-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-134216. MedChemExpress MCE
MAK683 MAK683 is an embryonic ectoderm development ( EED ) inhibitor extracted from patent US20160176882 A1, compound example 2. MAK683 exhibits IC 50 s of 59, 89, 26 nM in EED Alphascreen binding, LC-MS and ELISA assay [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1951408-58-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103663. MedChemExpress MCE
MAK683-CH2CH2COOH hydrochloride MAK683-CH2CH2COOH binds to EED (embryonic ectoderm development protein). MAK683-CH2CH2COOH and a VHL ligand for the E3 ubiquitin ligase have been used to design PROTAC EED degrader-1 (HY-130614) and PROTAC EED degrader-2 (HY-130615)[1]. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130815A. MedChemExpress MCE
Malabaricone C Malabaricone C is an orally active and noncompetitive sphingomyelin synthase ( SMS ) inhibitor with IC 50 values of 3 μM and 1.5 μM for SMS 1 and SMS 2, respectively. Malabaricone C reduces body weight gain, improves glucose tolerance, and decreases lipid accumulation in the liver, showing significant prevention of high fat diet-induced fatty liver in mice. Malabaricone C has anti-inflammatory effects, which is found in the fruits of Myristica cinnamomea King. Malabaricone C is promising for research of obesity and immunological disorders caused due to hyper-activation of T-cells [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 63335-25-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N8518. MedChemExpress MCE
Malachite green hemioxalate Malachite green hemioxalate (MCCK1) is a triphenylmethane dye which can be used to detect the release of phosphate in enzymatic reactions. Malachite green hemioxalate has antibacterial activity, which is attributed to inhibition of intracellular enzymes, insertion into DNA and/or interaction with cell membranes. Malachite green hemioxalate is also a potent and selective inhibitor of IKBKE , and inhibits its downstream targets such as IκBα , p65 and IRF3. Malachite green hemioxalate exhibits antitumor activity in vitro and in vivo [1] [2] [3]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: MCCK1. CAS No. 2437-29-8. Pack Sizes: 100 mg. Product ID: HY-D0162. MedChemExpress MCE
Mal-amide-PEG8-Val-Ala-PAB-PNP Mal-amide-PEG8-Val-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2210247-59-7. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148425. MedChemExpress MCE
Mal-amido-PEG9-amine TFA Mal-amido-PEG9-amine (TFA) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2569576-12-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-140976A. MedChemExpress MCE
Malaoxon Malaoxon is a pesticide metabolite. Malaoxon can induce cellular death in cultured human pulmonary cells. Malaoxon can be used for the research of pulmonary toxicity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1634-78-2. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-119904. MedChemExpress MCE
MALAT1-IN-1 MALAT1-IN-1 (compounds 5) is a potent and specific Malat1 (Metastasis-associated lung adenocarcinoma transcript 1) inhibitor. MALAT1-IN-1 modulated Malat1 downstream genes in a dose-dependent manner without affecting expression of nuclear enriched abundant transcript 1 (Neat1) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 827327-28-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115579. MedChemExpress MCE
Maleic Acid Maleic Acid is a Glutamate Decarboxylase (GAD) inhibitor of E. coli and L. monocytogenes. Uses: Scientific research. Group: Natural products. CAS No. 110-16-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 5 g. Product ID: HY-Y0367. MedChemExpress MCE
Maleic hydrazide Maleic hydrazide is extensively used as a systemic plant growth regulator and as a herbicide. Maleic hydrazide acts as an inhibitor of the synthesis of nucleic acids and proteins [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 123-33-1. Pack Sizes: 10 mM * 1 mL; 50 g; 100 g. Product ID: HY-59354. MedChemExpress MCE
Maleimide Maleimide can be used for production of antibody-drug conjugate (ADC) which is used in cancer research. Maleimide also be leveraged for the preparation of fluorogenic probe, which is mainly used for the specific detection of thiol analytes [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 541-59-3. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-W007324. MedChemExpress MCE
Maleimide-DOTA Maleimide-DOTA is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Uses: Scientific research. Group: Signaling pathways. Alternative Names: Maleimido-mono-amide-DOTA. CAS No. 1006711-90-5. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-133540. MedChemExpress MCE
Maleimide-NOTA Maleimide-NOTA is a chelator for the labeling of peptides and antibodies. Maleimide-NOTA can react with cysteine [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1295584-83-6. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W087027. MedChemExpress MCE
Mal-Gly-PAB-Exatecan-D-glucuronic acid Mal-Gly-PAB-Exatecan-D-glucuronic acid can be used for Antibody-Drug Conjugates (ADCs) synthesis. Mal-Gly-PAB-Exatecan-D-glucuronic acid can be used for research of tumor research and diagnosis[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2763252-25-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153179. MedChemExpress MCE
Malic acid Malic acid (Hydroxybutanedioic acid) is a dicarboxylic acid that occurs naturally in fruits like apples and pears with oral activities. Malic acid plays a role in many sour or tangy foods. Malic acid is an intermediate in the citric acid cycle [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Hydroxybutanedioic acid; E 296. CAS No. 6915-15-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 5 g. Product ID: HY-Y1311. MedChemExpress MCE
Malic acid disodium hydrate Malic acid disodium hydrate is an organic compound that is commonly used as a food additive, buffering agent, and nutritional supplement. It contains sodium and malic acid. Malic acid disodium hydrate has a variety of properties that make it suitable for these applications, including the ability to enhance food flavor, improve texture, and regulate acidity. In addition, due to its potential health benefits, including improved energy production, reduced fatigue, and enhanced athletic performance, Malic acid disodium hydrate can be used as a dietary supplement [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Hydroxybutanedioic acid disodium hydrate; Disodium DL-malate hydrate; E 296 disodium hydrate. CAS No. 63474-37-3. Pack Sizes: 500 mg; 5 g. Product ID: HY-W250303A. MedChemExpress MCE
Malic acid disodium salt Sodium DL-Malate is an organic compound commonly used as a food additive, buffer and nutritional supplement. It contains sodium and malic acid. Malic acid disodium salt has several properties suitable for these applications, including the ability to enhance food flavor, improve texture and regulate acidity. Additionally, it can be used as a dietary supplement due to its potential health benefits, including improved energy production, reduced fatigue, and enhanced athletic performance. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Hydroxybutanedioic acid disodium salt; E 296 disodium salt. CAS No. 676-46-0. Pack Sizes: 500 mg; 5 g. Product ID: HY-W250303. MedChemExpress MCE
Malic acid (Standard) Malic acid (Standard) is the analytical standard of Malic acid. This product is intended for research and analytical applications. Malic acid (Hydroxybutanedioic acid) is a dicarboxylic acid that is naturally found in fruits such as apples and pears. It plays a role in many sour or tart foods. Uses: Scientific research. Group: Natural products. CAS No. 6915-15-7. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-Y1311R. MedChemExpress MCE
Malic dehydrogenase, microorganism Malate dehydrogenase (EC 1.1.1.37) (MDH) catalyzes the mutual conversion of oxaloacetate and malate, and is associated with the oxidation/reduction of dinucleotide coenzymes [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MDH; EC 1.1.1.37. CAS No. 9001-64-3. Pack Sizes: 1 KU; 10 KU. Product ID: HY-P2809. MedChemExpress MCE
Malic enzyme inhibitor ME1 Malic enzyme inhibitor ME1 (ME1; compound 1) is a potent inhibitor of Malic enzyme (ME1) with an IC50 of 0.15 ?M[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ME1. CAS No. 522649-59-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124861. MedChemExpress MCE
Mal-NH2 TFA Mal-NH2 (TFA) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 146474-00-2. Pack Sizes: 100 mg. Product ID: HY-140988. MedChemExpress MCE
Malondialdehyde tetrabutylammonium Malondialdehyde tetrabutylammonium is a biomarker with antioxidant activity. Malondialdehyde tetrabutylammonium can be used as an indicator of lipid peroxidation to help assess oxidative stress levels. Malondialdehyde tetrabutylammonium is widely used in the food and cosmetics fields, mainly for monitoring and evaluating product stability and safety. Malondialdehyde tetrabutylammonium has an important role in indicating cell damage and is a potential biomarker for studying a variety of diseases. Uses: Scientific research. Group: Signaling pathways. CAS No. 100683-54-3. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-W749411. MedChemExpress MCE
Malonyl CoA lithium Malonyl CoA (Malonyl Coenzyme A) lithium is an inhibitor of carnitine palmitoyl transferase 1 ( CPT1 ). High Malonyl CoA lithium concentrations suppress fatty acid oxidation, while low Malonyl CoA lithium concentrations are permissive for fat oxidation [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Malonyl coenzyme A lithium. CAS No. 108347-84-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-136408. MedChemExpress MCE
Mal-PEG12-NHS ester Mal-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2669737-09-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-140963. MedChemExpress MCE
Mal-PEG24-NHS ester Mal-PEG24-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2226733-37-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-135819. MedChemExpress MCE
Mal-PEG2-acid Mal-PEG2-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Mal-PEG2-acid can be conjugated to Tubulysin (HY-128914) and its derivative cytotoxic molecule [1]. Mal-PEG2-acid is also a PROTAC linker that can be used in the synthesis of PROTACs. Uses: Scientific research. Group: Signaling pathways. CAS No. 1374666-32-6. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-130442. MedChemExpress MCE
Mal-PEG2-NH2 TFA Mal-PEG2-NH2 (TFA) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 660843-23-2. Pack Sizes: 50 mg; 100 mg. Product ID: HY-35261A. MedChemExpress MCE
Mal-PEG2-NHS Mal-PEG2-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 329364-72-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-138430. MedChemExpress MCE
Mal-PEG2-NHS ester Mal-PEG2-NHS ester is a nonclaevable ADC linker containing a Maleimide group, 2-unit PEG and an NHS ester. Uses: Scientific research. Group: Signaling pathways. CAS No. 1433997-01-3. Pack Sizes: 50 mg; 100 mg; 250 mg; 1 g; 5 g. Product ID: HY-126504. MedChemExpress MCE
Mal-PEG2-Val-Cit-PABA-PNP Mal-PEG2-Val-Cit-PABA-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1345681-52-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-131156. MedChemExpress MCE

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