MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Pangelin | Pangelin is a coumarin that can be found in Ducrosia anethifolia. Pangelin exhibits anti-mycobacterial and anti-tumor activities [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 33783-80-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N8131. |  |
| p-Anisic acid | p-Anisic acid (4-Methoxybenzoic acid) is an orally available tyrosinase inhibitor that has antioxidant, anti-anxiety, anti-inflammatory, anti-tumor, anti-diabetic, and preservative properties. p-Anisic acid can be used as a preservative in the cosmetics field [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: 4-Methoxybenzoic acid; Draconic acid. CAS No. 100-09-4. Pack Sizes: 10 mM * 1 mL; 5 g; 10 g. Product ID: HY-N1394. | |
| p-Anisic acid (Standard) | p-Anisic acid (Standard) is the analytical standard of p-Anisic acid. This product is intended for research and analytical applications. p-Anisic acid (4-Methoxybenzoic acid) is one of the isomers of anisic acid, with anti-bacterial and antiseptic properties [1]. Uses: Scientific research. Group: Natural products. Alternative Names: 4-Methoxybenzoic acid (Standard); Draconic acid (Standard). CAS No. 100-09-4. Pack Sizes: 100 mg; 250 mg; 500 mg. Product ID: HY-N1394R. | |
| Panitumumab | Panitumumab (ABX-EGF) is a fully human IgG2 anti- EGFR monoclonal antibody with anti-tumor activity. Panitumumab inhibits tumor cell proliferation, survival and angiogenesis. Panitumumab can be used in the research of cancers, such as colon cancer [1] [2] [4]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ABX-EGF. CAS No. 339177-26-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99041. | |
| Panobacumab | Panobacumab (KBPA101) is a fully human IgM/κ monoclonal antibody generated by immortalizing human B lymphocytes against the LPS O polysaccharide of serotype O11 of P. aeruginosa [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: KBPA101. CAS No. 885053-97-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99214. | |
| Panobinostat | Panobinostat (LBH589; NVP-LBH589) is a potent and orally active non-selective HDAC inhibitor, and has antineoplastic activities [1] [2]. Panobinostat induces HIV-1 virus production even at low concentration range 8-31 nM, stimulates HIV-1 expression in latently infected cells [4]. Panobinostat induces cell apoptosis and autophagy. Panobinostat can be used for the study of refractory or relapsed multiple myeloma [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LBH589; NVP-LBH589. CAS No. 404950-80-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-10224. | |
| Panobinostat lactate | Panobinostat lactate is a potent and orally active non-selective HDAC inhibitor. Panobinostat lactate has antineoplastic activities. Panobinostat lactate effectively disrupts HIV latency. Panobinostat lactate induces cell apoptosis and autophagy. Panobinostat lactate can be used for the study of refractory or relapsed multiple myeloma [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LBH589 lactate; NVP-LBH589 lactate. CAS No. 960055-56-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10224A. | |
| Pantethine | Pantethine is an orally active lipid-lowering agent. Pantethine has anti-tumor, anti-inflammatory and anti-SARS-COV virus activities. Pantethine is also a neuroprotective agent. Pantethine can be used in the study of Alzheimer's disease, Parkinson's disease, major depression, systemic sclerosis and pantothenate kinase-related neurodegeneration [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Natural products. Alternative Names: D-Pantethine; LBF disulfide. CAS No. 16816-67-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-B1028. | |
| Pantolactone | Pantolactone is an endogenous metabolite. Uses: Scientific research. Group: Natural products. CAS No. 599-04-2. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-W010396. | |
| Pantoprazole | Pantoprazole (BY10232) is an orally active and potent proton pump inhibitor (PPI) [1]. Pantoprazole, a substituted benzimidazole, is a potent H + /K + -ATPase inhibitor with an IC 50 of 6.8 μM. Pantoprazole improves pH stability and has anti-secretory, anti-ulcer activities. Pantoprazole significantly increased tumor growth delay combined with Doxorubicin (HY-15142) [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BY1023; SKF96022. CAS No. 102625-70-7. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-17507. | |
| Pantoprazole sodium | Pantoprazole sodium (BY10232 sodium) is an orally active and potent proton pump inhibitor (PPI) [1]. Pantoprazole sodium, a substituted benzimidazole, is a potent H + /K + -ATPase inhibitor with an IC 50 of 6.8 μM. Pantoprazole sodium improves pH stability and has anti-secretory, anti-ulcer activities. Pantoprazole sodium significantly increased tumor growth delay combined with Doxorubicin (HY-15142) [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BY1023 sodium; SKF96022 sodium. CAS No. 138786-67-1. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-17507A. | |
| Pantoprazole sodium hydrate | Pantoprazole sodium hydrate (BY10232 sodium hydrate) is an orally active and potent proton pump inhibitor (PPI) [1]. Pantoprazole sodium hydrate, a substituted benzimidazole, is a potent H + /K + -ATPase inhibitor with an IC 50 of 6.8 μM. Pantoprazole sodium hydrate improves pH stability and has anti-secretory, anti-ulcer activities. Pantoprazole sodium hydrate significantly increased tumor growth delay combined with Doxorubicin (HY-15142) [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BY1023 sodium hydrate; SKF96022 sodium hydrate. CAS No. 164579-32-2. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg. Product ID: HY-17507B. | |
| Pantothenate kinase-IN-2 | Pantothenate kinase-IN-2 is a potent Pantothenate kinase 1/3 (PanK1/3) inhibitor with an IC 50 of 0.14 μM and 0.36 μM. Pantothenate kinase-IN-2 is a promising agent for PKAN (PanK-associated neurodegeneration) and diabetes research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 902614-04-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-44170. | |
| Papain | Papain is a cysteine protease of the peptidase C1 family, which is used in food, pharmaceutical, textile, and cosmetic industries. Uses: Scientific research. Group: Natural products. CAS No. 9001-73-4. Pack Sizes: 100 mg. Product ID: HY-P1645. | |
| PAPA NONOate | PAPA NONOate is a NO donor with a NO release half-life of 77 min (22-25°C). PAPA NONOate may represent a potential research for impaired wound healing in diabetes by increasing the rate of collagen synthesis at the wound site [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 146672-58-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-134636. | |
| Paquinimod | Paquinimod (ABR 215757) is a specific and orally active inhibitor of S100A8/S100A9. Paquinimod rescues the pneumonia with substantial reduction of viral loads in SARS-CoV-2-infected mice [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABR-215757; ABR 25757. CAS No. 248282-01-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100442. | |
| PAR | PAR is an azo dye widely used as a colorimetric reagent for metal ions. PAR forms stable chelates with different metal ions. PAR can also complex with heavy metal ions in polar organic solvent like ethanol [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1141-59-9. Pack Sizes: 1 g. Product ID: HY-W115738. | |
| PAR-2 (1-6) (human) | PAR-2 (1-6) (human) (SLIGKV), a peptide ligand, is a PAR-2 agonist [1]. Uses: Scientific research. Group: Peptides. CAS No. 202933-49-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P4803. | |
| PAR-4 Agonist Peptide, amide | PAR-4 Agonist Peptide, amide (PAR-4-AP; AY-NH2) is a proteinase-activated receptor-4 ( PAR-4 ) agonist, which has no effect on either PAR-1 or PAR-2 and whose effects are blocked by a PAR-4 antagonist. Uses: Scientific research. Group: Peptides. Alternative Names: PAR-4-AP; AY-NH2. CAS No. 352017-71-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1309. | |
| PAR-4 Agonist Peptide, amide TFA | PAR-4 Agonist Peptide, amide TFA (PAR-4-AP TFA; AY-NH2 TFA) is a proteinase-activated receptor-4 ( PAR-4 ) agonist, which has no effect on either PAR-1 or PAR-2 and whose effects are blocked by a PAR-4 antagonist [1]. Uses: Scientific research. Group: Peptides. Alternative Names: PAR-4-AP TFA; AY-NH2 TFA. CAS No. 1228078-65-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1309A. | |
| Paracetamol-cysteine TFA | Paracetamol-cysteine (TFA) is an acetaminophen-protein adduct formed during the metabolism of acetaminophen (HY-66005) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1331891-93-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-139093A. | |
| Paradol | Paradol is a pungent phenolic substance found in ginger and other Zingiberaceae plants. Paradol is an effective inhibitor of tumor promotion in mouse skin carcinogenesis, binds to cyclooxygenase (COX)-2 active site. Uses: Scientific research. Group: Natural products. Alternative Names: [6]-Gingerone; [6]-Paradol. CAS No. 27113-22-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-14617. | |
| Paraherquamide E | Paraherquamide E is a fungal metabolite found in Penicillium charlesii. Paraherquamide E has antinematodal and antiparasitic effects [1]. Uses: Scientific research. Group: Natural products. CAS No. 125600-53-5. Pack Sizes: 500 μg. Product ID: HY-N10220. | |
| Paramethasone Acetate | Paramethasone acetate is a synthetic glucocorticoid, and shows anti-inflammatory and immunosuppressant activities [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1597-82-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-107939. | |
| Para-nitrophenyllinoleate | Para-nitrophenyllinoleate is an ester product. Uses: Scientific research. Group: Signaling pathways. CAS No. 6562-50-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-165831. | |
| Pararosaniline hydrochloride | Pararosaniline hydrochloride (Basic red 9) is a pH-responsive basic dye, as a biological stain to track certain proteins. The pH of the acidified Pararosaniline hydrochloride reagent has a significant effect on the color and the maximum absorption wavelength (λmax) of the reaction system, with its optimum pH 0.48 and a λmax at 549?nm. Pararosaniline hydrochloride is also a strong modifier of RNA splicing. Pararosaniline hydrochloride has been used in the analysis of SO 2 and formaldehyde and staining of bacteria or other organisms. Pararosaniline hydrochloride is extensively used in industries like textile, printing, paper, cosmetic, and leather [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Basic red 9. CAS No. 569-61-9. Pack Sizes: 10 g; 25 g. Product ID: HY-W127770. | |
| Parathyroid Hormone (1-34), bovine | Parathyroid Hormone (1-34), bovine is a potent parathyroid hormone (PTH) receptor agonist. Parathyroid Hormone (1-34), bovine increases calcium and inorganic phosphate levels in vivo. Parathyroid Hormone (1-34), bovine can be used for th reseach of osteoporosis [1]. Uses: Scientific research. Group: Peptides. CAS No. 12583-68-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1252. | |
| Parathyroid hormone (1-34) (rat) | Parathyroid hormone (1-34) (rat) is a parathyroid hormone. Parathyroid hormone (1-34) (rat) improves both cortical and cancellous bone structure. Parathyroid hormone (1-34) (rat) can be used for the research of osteoporosis [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 98614-76-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P2279. | |
| Paraxanthine | Paraxanthine, a caffeine metabolite, provides protection against Dopaminergic cell death via stimulation of Ryanodine Receptor Channels. Uses: Scientific research. Group: Natural products. CAS No. 611-59-6. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-W016498. | |
| Parbendazole | Parbendazole is a potent inhibitor of microtubule assembly, destabilizes tubulin, with an EC 50 of 530 nM, and exhibits a broad-spectrum anthelmintic activity. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SKF 29044. CAS No. 14255-87-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115364. | |
| Parcetasal | Paclitaxal is a non-steroidal anti-inflammatory analgesic. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MR-897. CAS No. 87549-36-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 20 mg; 50 mg; 100 mg. Product ID: HY-U00100. | |
| Pardoprunox hydrochloride | Pardoprunox (SLV-308) hydrochloride is a partial dopamine D2 and D3 receptor partial agonist and a serotonin 5-HT1A receptor agonist, with pEC 50 s of 8, 9.2, and 6.3, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SLV-308 hydrochloride; DU-126891 hydrochloride. CAS No. 269718-83-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14958A. | |
| Parecoxib | Parecoxib (SC 69124) is a highly selective and orally active COX-2 inhibitor, the proagent of Valdecoxib (HY-15762). Parecoxib Sodium is a nonsteroidal anti-inflammatory agent (NSAID) and inhibits prostaglandin (PG) synthesis. Parecoxib can be used for the relief of acute postoperative pain and symptoms of chronic inflammatory conditions such as osteoarthritis and rheumatoid arthritis in vivo. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SC 69124. CAS No. 198470-84-7. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-17474. | |
| Parecoxib Sodium | Parecoxib Sodium (SC 69124A) is a highly selective and orally active COX-2 inhibitor, the proagent of Valdecoxib (HY-15762). Parecoxib Sodium is a nonsteroidal anti-inflammatory agent (NSAID) and inhibits prostaglandin (PG) synthesis. Parecoxib Sodium can be used for the relief of acute postoperative pain and symptoms of chronic inflammatory conditions such as osteoarthritis and rheumatoid arthritis in vivo. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SC 69124A. CAS No. 198470-85-8. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-17474A. | |
| Pargyline | Pargyline is an irreversible monoamine oxidase (MAO) inhibitor with K i s of 13 μM and 0.5 μM for MAO-A and MAO-B , respectively. Pargyline has antihypertensive and anticancer activities [1] [2] [3]. Pargyline is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 555-57-7. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-A0091A. | |
| Pargyline hydrochloride | Pargyline hydrochloride is an irreversible monoamine oxidase (MAO) inhibitor with K i s of 13 μM and 0.5 μM for MAO-A and MAO-B , respectively. Pargyline hydrochloride has antihypertensive and anticancer activities [1] [2] [3]. Pargyline (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 306-07-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-A0091. | |
| Paricalcitol | Paricalcitol, a vitamin D analogue, is a vitamin D receptor agonist, used for the prevention and treatment of secondary hyperparathyroidism (excessive secretion of parathyroid hormone) associated with chronic renal failure. Uses: Scientific research. Group: Signaling pathways. CAS No. 131918-61-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-50919. | |
| Paridiprubart | Paridiprubart (NI-0101) is a humanised anti-TLR4 monoclonal antibody. Paridiprubart has the potential for the research of rheumatoid arthritis [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: NI-0101. CAS No. 2641646-59-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-145645. | |
| Paritaprevir | Paritaprevir (ABT-450) is a potent, orally active and antiviral non-structural protein 3/4A (NS3/4A) protease inhibitor with EC 50 s of 1 and 0.21 nM against HCV 1a and 1b, respectively. Paritaprevir is also a SARS-CoV 3CL pro inhibitor with an IC 50 of 1.31 μM. Paritaprevir is metabolized primarily by cytochrome P450 (CYP) 3A. The plasma concentration and half-life of Paritaprevir can be enhanced by Ritonavir (a CYP450 inhibitor) [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABT-450; Veruprevir. CAS No. 1216941-48-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12594. | |
| Paromomycin sulfate | Paromomycin (Aminosidine) sulfate, a neomycin (HY-B0470) derivative, is a broad spectrum aminoglycoside antibiotic with amebicidal and bactericidal effects. Paromomycin sulfate prematures termination of translation of mRNA and inhibits protein synthesis by specifically binds to the RNA oligonucleotide at the A site of bacterial 30S ribosomes. Paromomycin sulfate can be used for the research of bacterial and parasitic infections [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Aminosidine sulfate. CAS No. 1263-89-4. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-B0956. | |
| Paroxetine | Paroxetine is an oral | |
| Paroxetine hydrochloride | Paroxetine hydrochloride is a potent selective serotonin-reuptake inhibitor, commonly prescribed as an GRK2 inhibitor with IC 50 of 14?μM. Paroxetine hydrochloride can be used for the research of depressive disorder [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BRL29060 hydrochloride; BRL29060A. CAS No. 78246-49-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0492. | |
| Paroxetine hydrochloride hemihydrate | Paroxetine hydrochloride hemihydrate is a potent selective serotonin-reuptake inhibitor, commonly prescribed as an antidepressant and has GRK2 inhibitory ability with IC 50 of 14?μM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BRL29060 hydrochloride hemihydrate; BRL29060A hemihydrate. CAS No. 110429-35-1. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0492A. | |
| PARP10-IN-2 | PARP10-IN-2 is a potent mono?ADP?ribosyltransferase PARP10 inhibitor with an IC 50 of 3.64 μM for human PARP10. PARP10-IN-2 reveals potent inhibition on PARP2 and PARP15 with IC 50 s of 27 μM and 11 μM for human PARP2 and human PARP15, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1042780-52-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148753. | |
| PARP10-IN-3 | PARP10-IN-3 is a selective mono?ADP?ribosyltransferase PARP10 inhibitor with an IC 50 of 480 nM for human PARP10. PARP10-IN-3 reveals potent inhibition on PARP2 and PARP15 with IC 50 s of 1.7 μM for human PARP2 and human PARP15, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2225800-19-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148754. | |
| PARP1-IN-11 | PARP1-IN-11 (compound 49) is a potent PARP1 inhibitor with IC 50 value of 0.082 μM. PARP1-IN-11 shows complete inhibition of PARP2 and substantially inhibits PARP3, TNKS1 and TNKS2 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2482484-87-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147886. | |
| PARP-1-IN-2 | PARP-1-IN-2 (compound 11g) is a potent and BBB-penetrated PARP1 inhibitor, with an IC 50 of 149 nM. PARP1-IN-2 shows significantly potent anti-proliferative activity against Human lung adenocarcinoma epithelial cell line A549. PARP1-IN-2 can induce A549 cells apoptosis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 684234-55-7. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-147027. | |
| PARP1-IN-29 | PARP1-IN-29 is an orally active PARP-1 inhibitor with an IC 50 value of 6.3 nM. PARP1-IN-29, after being labeled with [18F], can be used for positron emission tomography (PET) imaging, specifically targeting PARP-1 in tumors. PARP1-IN-29 is applicable in the fields of oncology and imaging research, particularly for detecting PARP-1 activity in cancer [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1567375-93-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-164475. | |
| PARP-1-IN-3 | PARP-1-IN-3, a benzamide derivative, is a potent PARP-1 inhibitor with IC 50 values of 0.25 nM and 2.34 nM for PARP-1 and PARP-2, respectively. PARP-1-IN-3 induces apoptosis and arrest cell cycle at G2/M phase. PARP-1-IN-3 can be used in research of cancer [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2976342-33-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-149800. | |
| PARP1-IN-31 | PARP1-IN-31 (compound 11f) is a phthalazinone-based compound, an anti-lung adenocarcinoma compound with inhibitory activity against PARP-1 ( IC 50 value of 97 nM), inducing apoptosis and inhibiting cell proliferation in lung cancer cell lines. Uses: Scientific research. Group: Signaling pathways. CAS No. 684234-60-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-164713. | |
| PARP1-IN-33 | PARP1-IN-33 (Example 6) is a PARP1 inhibitor ( IC 50 : 0.41 nM). PARP1-IN-33 has retinal cytoprotective effect, with an EC 50 of 0.02 nM (inhibition on MTS activity of H 2 O 2 induced human retinal pigment epithelial cell) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2640677-68-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-164926. | |
| PARP-1-IN-4 | PARP-1-IN-4 is a PARP-1 inhibitor. PARP-1-IN-4 has inhibitory activity against PARP-1 with IC 50 value of 302 μM. PARP-1-IN-4 can be used for the research of lung adenocarcinoma [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 684234-56-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-153590. | |
| PARP1-IN-8 | PARP1-IN-8 (compound 11c) is a potent and BBB-penetrated PARP1 inhibitor, with an IC 50 of 97 nM. PARP1-IN-8 shows significantly potent anti-proliferative activity against Human lung adenocarcinoma epithelial cell line A549 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 836640-15-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-147030. | |
| PARP7-IN-15 | PARP7-IN-15 (Compound 18) is a PARP7 inhibitor with IC 50 of 0.56 nM, that has antitumor activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2819998-97-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-155351. | |
| Parsaclisib | Parsaclisib (INCB050465) is a potent, selective and orally active inhibitor of PI3Kδ , with an IC 50 of 1 nM at 1 mM ATP. Parsaclisib shows approximately 20000-fold selectivity over other PI3K class I isoforms. Parsaclisib can be used for the research of relapsed or refractory B-cell malignancies [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: INCB050465; IBI-376. CAS No. 1426698-88-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109068. | |
| Parsaclisib hydrochloride | Parsaclisib hydrochloride (INCB050465 hydrochloride) is a potent, selective and orally active inhibitor of PI3Kδ , with an IC 50 of 1 nM at 1 mM ATP. Parsaclisib hydrochloride shows approximately 20000-fold selectivity over other PI3K class I isoforms. Parsaclisib hydrochloride can be used for the research of relapsed or refractory B-cell malignancies [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: INCB050465 hydrochloride; IBI-376 hydrochloride. CAS No. 1995889-48-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109068A. | |
| Parsatuzumab | Parsatuzumab (Anti-EGFL7; RG 7414) is a humanized monoclonal antibody, acts as an immunomodulator and binds to EGFL7. Parsatuzumab selectively blocks the interaction between EGFL7 and endothelial cells, potentially inhibiting vascular regrowth and reducing vascular endothelial growth factor ( VEGF ) inhibition [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-EGFL7; RG 7414. CAS No. 1312797-14-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99215. | |
| Pascolizumab | Pascolizumab (SB-240683) is a humanized anti-IL-4 monoclonal antibody. Pascolizumab has the potential for the research of asthma [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: SB-240683. CAS No. 331243-22-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99801. | |
| Pasireotide | Pasireotide (SOM230), a long-acting cyclohexapeptide somatostatin analogue, can improve agonist activity at somatostatin receptors (subtypes sst1/2/3/4/5 , pK i =8.2/9.0/9.1/<7.0/9.9, respectively). Pasireotide can suppress GH, IGF-I and ACTH secretion, indicating potential efficacy in acromegaly and Cushing's disease. Pasireotide also exhibits antisecretory, antiproliferative, and proapoptotic activity [1] [2] [3]. Uses: Scientific research. Group: Peptides. Alternative Names: SOM230. CAS No. 396091-73-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-16381. | |
| Pasireotide acetate | Pasireotide (SOM230) acetate, a long-acting cyclohexapeptide somatostatin analogue, can improve agonist activity at somatostatin receptors (subtypes sst1/2/3/4/5 , pK i =8.2/9.0/9.1/<7.0/9.9, respectively). Pasireotide acetate can suppress GH, IGF-I and ACTH secretion, indicating potential efficacy in acromegaly and Cushing's disease. Pasireotide acetate also exhibits antisecretory, antiproliferative, and proapoptotic activity [1] [2] [3]. Uses: Scientific research. Group: Peptides. Alternative Names: SOM230 acetate. CAS No. 396091-76-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-16381A. | |
| Pasotuxizumab | Pasotuxizumab (BAY 2010112) is a PSMA and CD3 bispecific T-cell engager (BiTE). Pasotuxizumab binds to CD3 and PSMA with K D s of 9.4 nM and 47.0 nM for human CD3 and PSMA. Pasotuxizumab can be used for research of metastatic castration-resistant prostate cancer (mCRPC) [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BAY 2010112; AMG 212. CAS No. 1442657-12-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99802. | |
| Patamostat | Patamostat (E-3123) is a potent protease inhibitor. Patamostat potently inhibits trypsin, plasmin and thrombin with IC 50 s of 39 nM, 950 nM and 1.9 μM, respectively. Patamostat may possess suppressing effects on pathogenesis and development of acute pancreatitis [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: E-3123. CAS No. 114568-26-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114080. | |
| Patchouli alcohol | Patchouli alcohol is a natural tricyclic sesquiterpene, exhibits anti- Helicobacter pylori , anti-inflammatory and antioxidant properties [1]. Uses: Scientific research. Group: Natural products. CAS No. 5986-55-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-N0207. | |
| Pateclizumab | Pateclizumab (MLTA3698A) is a humanized antibody against lymphotoxin α (LTα) , a transiently expressed cytokine on activated B and T cells (Th1, Th17), which are implicated in rheumatoid arthritis (RA) pathogenesis [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MLTA3698A; RG7415; PRO283698. CAS No. 1202526-59-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990034. | |
| Patent Blue V | Patent Blue V (Acid blue 1) is a novel biological dye that can be used as an intraocular dye for retinectomy. Retinectomy refers to the removal of the translucent inner limiting membrane (ILM). The application of appropriate dyes in vitreoretinal surgery can achieve the purpose of complete removal. Patent Blue V can be used to stain retinal premembranous structures. Spectral analysis shows that Patent Blue V has strong absorption below 450 nm and above 600 nm, showing a blue-green color. Patent Blue V is also used as a marker in lymphangiography for resection of neoplastic lymph nodes [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Acid blue 1. CAS No. 129-17-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-W110929. | |
| Patent Blue V calcium salt | Patent Blue V has been widely used in sentinel lymph node mapping. Patent Blue V is also a food coloring agent and an alternative dye for trypan blue (TB) in descemet membrane endothelial keratoplasty (DMEK) [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 3536-49-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-126395. | |
| Patiromer | Patiromer is an orally active and potent hyperkalemia inhibitor and a nonabsorbed potassium binder. Patiromer polymer is bound with calcium which is released in the colon in exchange for binding potassium [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1208912-84-8. Pack Sizes: 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-112961. | |
| Patritumab | Patritumab (Human Anti-ERBB3 Recombinant Antibody) is a neutralizing monoclonal antibody to ERBB3. Patritumab shows a synergy with Cetuximab (HY-P9905), potently inhibits the phosphorylation of EGFR , HER2 , HER3 , ERK , and AKT. Patritumab also induces cell apoptosis and suppresses the growth of pancreatic, non-small cell lung cancer, and colorectal cancer xenograft tumors [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Human Anti-ERBB3 Recombinant Antibody. CAS No. 1262787-83-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99275. | |
| Patritumab deruxtecan | Patritumab deruxtecan (HER3-DXd) is an antibody-drug conjugate (ADC) consisting of a fully human anti-HER3 IgG1 monoclonal antibody Patritumab (HY-P99275) attached to a topoisomerase I inhibitor payload via a tetrapeptide-based cleavable linker. Patritumab deruxtecan shows anticancer activity [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: HER3-DXd; U3-1402. CAS No. 2227102-46-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99813. | |
| Patulin | Patulin (Terinin) is a mycotoxin produced by fungi including the Aspergillus , Penicillium , and Byssochlamys species, causes chromosome breakage, mutation, teratogenic and cytotoxic. Patulin induces autophagy-dependent apoptosis through lysosomal-mitochondrial axis, and causes DNA damage [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Terinin. CAS No. 149-29-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N6779. | |
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