MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
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MCU-i4
MCU-i4 blocks the IP3-dependent mitochondrial Ca2+-uptake, maintaining the gatekeeping role of their target[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 371924-24-2. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138620.
MC-Val-Cit-PAB
MC-Val-Cit-PAB is a cleavable ADC Linker that forms part of VcMMAE (HY-15575). VcMMAE is Drug-Linker Conjugates for ADCs. The ADC Cytotoxin in VcMMAE is MMAE, a tubulin polymerization inhibitor. Uses: Scientific research. Group: Signaling pathways. CAS No. 159857-80-4. Pack Sizes: 5 mg; 10 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-78738.
Mc-Val-Cit-PABC-PNP
Mc-Val-Cit-PABC-PNP is a cathepsin cleavable linker for antibody-drug conjugates (ADCs) which couples the antibody element to the effecting compound. Mc-Val-Cit-PABC-PNP can be used in the synthesis of ADCs[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Maleimidocaproyl-L-valine-L-citrulline-p-aminobenzyl alcohol p-nitrophenyl carbonate. CAS No. 159857-81-5. Pack Sizes: 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-20336.
MC-Val-Cit-PAB-Exatecan
MC-Val-Cit-PAB-Exatecan (MC-Val-Cit-PAB-DX8951) is a agent-linker conjugate for ADC. MC-Val-Cit-PAB-Exatecan is composed of a DNA topoisomerase I DX-8951 (HY-13631) and a cathepsin cleavable ADC linker. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MC-Val-Cit-PAB-DX8951. CAS No. 2504068-28-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145929.
MC-Val-Cit-PAB-MMAF
MC-Val-Cit-PAB-MMAF (Vc-MMAF) is a drug-linker conjugate for ADC by using the tubulin inhibitor, MMAF (HY-15579), linked via cathepsin cleavable MC-Val-Cit-PAB (HY-78738). MC-Val-Cit-PAB-MMAF shows antitumor activity[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Vc-MMAF. CAS No. 863971-17-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-112786.
MC-VA-PABC-MMAE
MC-VA-PABC-MMAE is a agent-linker conjugate for ADC. MC-VA-PABC-MMAE contains the ADCs linker (peptide MC-VA-PABC) and a potent tubulin polymerization inhibitor MMAE (HY-15162)[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1818864-51-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-147239.
MC-VA-PAB-Exatecan
MC-VA-PAB-Exatecan is a agent-linker conjugate for ADC. MC-VA-PAB-Exatecan contains the ADC linker (peptide MC-VA-PAB) and a DNA topoisomerase I inhibitor Exatecan (HY-13631). MC-VA-PAB-Exatecan synthesized ADC shows good antitumor activity[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2680543-57-9. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-147270.
MC-VC-PABC-amide-PEG1-CH2-CC-885
MC-VC-PABC-amide-PEG1-CH2-CC-885 (compound I-1) is a neoDegrader-Linker conjugate, consists of the GSPT1 degrader/molecular glue CC-885 (HY-101488) and a linker. MC-VC-PABC-amide-PEG1-CH2-CC-885 can be conjugated to the antibody DAR3.7 that specifically targets CD56 to synthesize Antibody-Drug Conjugates (ADCs)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2722697-82-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145448.
MC-VC-PABC-Aur0101
MC-VC-PABC-Aur0101 is a agent-linker conjugate for ADC with potent antitumor activity by using Aur0101 (an auristatin microtubule inhibitor), linked via the ADC linker MC-VC-PABC. Uses: Scientific research. Group: Signaling pathways. CAS No. 1438849-92-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128955.
Mc-VC-PAB-SN38
Mc-VC-PAB-SN38 consists a cleavable ADC linker (Mc-VC-PAB) and a DNA topoisomerase I inhibitor (SN38). Mc-VC-PAB-SN38 can be used in the synthesis of antibody-drug conjugates (ADCs)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1801838-28-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-131057.
MD-224
MD-224 is a first-in-class and highly potent small-molecule human murine double minute 2 (MDM2) degrader based on the proteolysistargeting chimera (PROTAC) concept. MD-224 consists of ligands for Cereblon and MDM2. MD-224 induces rapid degradation of MDM2 at concentrations <1 nM in human leukemia cells, and achieves an IC50 value of 1.5 nM in inhibition of growth of RS4;11 cells. MD-224 has the potential to be a new class of anticancer agent[1]. MD-224 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 2136247-12-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-114312.
MDA 19
MDA 19 is a potent and selective agonist of human cannabinoid receptor 2 (CB2) , with a K i of 43.3 nM. MDA 19 has antiallodynic effects in a rat model of neuropathic pain and does not affect rat locomotor activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1048973-47-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15451.
MDH1-IN-1
MDH1-IN-1 (Compound 5i) is a potent inhibitor of MDH1 with an IC50 of 6.79 ?M. MDH1-IN-1 has the potential for the research of cancer diseases[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2143463-31-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147790.
MDH1-IN-2
MDH1-IN-2 (Compound 7c) is a selective MDH1 inhibitor, with IC50 values of 2.27 and 27.47 ?M for MDH1 and MDH2, respectively. MDH1-IN-2 can reduce the generation of ROS by inhibiting the conversion of 2-Ketoglutaric acid (HY-W013636) to ?-Hydroxyglutaric acid (HY-113038B) mediated by MDH1, thereby suppressing 2-Ketoglutaric acid (HY-W013636)-induced ferroptosis[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2143463-35-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147791.
MDI-2268
MDI-2268 is an inhibitor of plasma kallikrein inhibitor 1 (PAI-1). MDI-2268 has good antithrombotic properties and regulates blood coagulation and fibrinolysis process by enhancing fibrinolysis. MDI-2268 can be used in research areas such as deep vein thrombosis[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1609176-50-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124577.
Mdivi-1
Mdivi-1 is a selective dynamin-related protein 1 ( Drp1 ) inhibitor. Mdivi-1 is a mitochondrial division/ mitophagy inhibitor. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Mitochondrial division inhibitor 1. CAS No. 338967-87-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15886.
MDL 105519
MDL 105519 is a potent and selective antagonist of glycine binding to the NMDA receptor. Uses: Scientific research. Group: Signaling pathways. CAS No. 161230-88-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15085.
MDL12330A
MDL12330A (RMI12330A) is an adenyl cyclase inhibitor. MDL12330A inhibits the vasopressin action on the short-circuit current (SCC). MDL12330A is also an inhibitor of cAMP phosphodiesterase [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RMI12330A. CAS No. 40297-09-4. Pack Sizes: 5 mg. Product ID: HY-103192.
MDL-28170
MDL-28170 (Calpain Inhibitor III) is a potent, selective and membrane-permeable cysteine protease inhibitor of calpain that rapidly penetrates the blood-brain barrier following systemic administration [1] [2]. MDL-28170 also block γ-secretase [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Calpain Inhibitor III. CAS No. 88191-84-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18236.
ME0328 is a potent and selective ARTD3 / PARP3 inhibitor with an IC 50 of 0.89±0.28 μM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1445251-22-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100225.
ME-344
ME-344 is a mitochondrial inhibitor. ME-344 has significant biological antitumor activity in HER2-negative breast cancer [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1374524-68-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112749.
Mead acid
Mead acid (5,8,11-Eicosatrienoic acid), an unsaturated (Omega-9) fatty acid, is an indicator of essential fatty acid deficiency [1]. Uses: Scientific research. Group: Natural products. Alternative Names: 5,8,11-Eicosatrienoic acid. CAS No. 20590-32-3. Pack Sizes: 1 mg (32.63 mM * 100 μL in Ethanol). Product ID: HY-108398A.
MeAIB
MeAIB (?-(Methylamino)isobutyric acid) is a specific?substrate for amino acid transport system A (ATA1). ATA mediate the uptake of short-chain neutral amino acids in a Na+-dependent manner[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ?-(Methylamino)isobutyric acid. CAS No. 2566-34-9. Pack Sizes: 10 mM * 1 mL; 250 mg. Product ID: HY-134452.
Mebendazole
Mebendazole is a highly effective, broad-spectrum antihelmintic against nematode infestations. Mebendazole also exhibits inhibitory effect against glioblastoma multiforme (GBM), inhibits Hedgehog pathway and tubulin polymerization. Mebendazole is orally active and can cross CNS penetration [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 31431-39-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-17595.
Mebeverine hydrochloride
Mebeverine hydrochloride, a β-phenylethylamine derivative, is a musculotropic agent that potently blocks intestinal peristalsis. Mebeverine directly blocks voltage-operated sodium channels and inhibits intracellular calcium accumulation [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2753-45-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0078.
Mebhydrolin
Mebhydrolin is a specific histamine H 1 receptor antagonist. Uses: Scientific research. Group: Signaling pathways. CAS No. 524-81-2. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B1303A.
Mebhydrolin napadisylate
Mebhydrolin napadisylate is a specific histamine H 1 receptor antagonist. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Mebhydroline 1,5-naphthalenedisulfonate salt. CAS No. 6153-33-9. Pack Sizes: 50 mg. Product ID: HY-B1303.
MeBIO
MeBIO is a potent AhR (aryl hydrocarbon receptor) agonist, with IC50 of 44 ?M (GSK-3) and 55 ?M (CDK1/cyclin B), respectively[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 667463-95-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-103221.
Mebrofenin
Mebrofenin (SQ 26962) is a type of iminodiacetic acid (IDA). Mebrofenin is available as a ready to use the kit for radio-labeling with Tc-99m. Tc-99m Mebrofenin, a diagnostic agent, is used for hepatobiliary imaging. Tc-99m Mebrofenin is the radiopharmaceutical of choice for the evaluation of hepatic function [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: SQ 26962. CAS No. 78266-06-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1684.
Mecamylamine hydrochloride
Mecamylamine hydrochloride is an orally active, nonselective, noncompetitive nAChR antagonist. Mecamylamine hydrochloride is also a ganglionic blocker. Mecamylamine hydrochloride can across the blood-brain barrier. Mecamylamine hydrochloride can be used in the research of neuropsychiatric disorders, hypertension, antidepressant area [1] [2] [5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 826-39-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-B1395.
Mecasermin
Mecasermin (Human IGF-I; FK 780) is a recombinant human insulin-like growth factor I (IGF-I). Mecasermin has the potential for the study of the growth failure of growth hormone (GH) insensitivity caused by GH receptor defects or GH-inhibiting antibodies [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Human IGF-I; FK 780. CAS No. 68562-41-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-108905.
Mecillinam
Mecillinam (Amdinocillin), the β-lactam antibiotic, has a broad spectrum of activity against gram-negative organisms [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Amdinocillin; FL 1060. CAS No. 32887-01-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 100 mg. Product ID: HY-A0269.
Meclizine dihydrochloride
Meclizine (Meclozine) dihydrochloride, an antihistamine , reversibly inhibits the interaction of histamine at the H1 receptors. Meclizine dihydrochloride is a member of the piperazine class of H1 antagonists. Meclizine dihydrochloride is an effective anti-motion sickness agent. Meclizine dihydrochloride crosses the blood-brain barrier. Meclizine dihydrochloride can be used for the research of polyQ toxicity disorders, such as Huntington's disease. Meclizine dihydrochloride is an agonist ligand for mouse constitutive androstane receptor (CAR) and an inverse agonist for Human CAR [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Meclozine dihydrochloride. CAS No. 1104-22-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 5 g. Product ID: HY-B0349.
Meclofenamic acid
Meclofenamic acid (Meclofenamate) is a non-steroidal anti-inflammatory agent. Meclofenamic acid is a highly selective FTO (fat mass and obesity-associated) enzyme inhibitor. Meclofenamic acid competes with FTO binding for the m(6)A-containing nucleic acid. Meclofenamic acid is a non-selective gap-junction blocker. Meclofenamic acid inhibits hKv2.1 and hKv1.1 , with IC 50 values of 56.0 and 155.9 μM, respectively [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Meclofenamate. CAS No. 644-62-2. Pack Sizes: 10 mM * 1 mL; 1 mg. Product ID: HY-117275.
Meclofenamic acid sodium
Meclofenamic acid (Meclofenamate) sodium is a non-steroidal anti-inflammatory agent (NSAID). Meclofenamic acid sodium is a non-selective gap-junction blocker and a highly selective inhibitor of fat - and obesity-related enzyme (FTO). Meclofenamic acid sodium has anti-inflammatory and antitumor activities [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Meclofenamate sodium. CAS No. 6385-02-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg. Product ID: HY-B1320.
Meclofenoxate hydrochloride
Meclofenoxate (Centrophenoxine) hydrochloride is an ester synthesized from DMAE and pCPA, capable of crossing the blood-brain barrier, and can stimulate memory and enhance cognition [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Centrophenoxine hydrochloride. CAS No. 3685-84-5. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-17555.
Meclonazepam
Meclonazepam (Ro 11-3128) is a benzodiazepine compound with anxiolytic effect [1]. Meclonazepam is active against immature S. mansoni. Meclonazepam (30 μM) eliminates 100% of immature parasites. Meclonazepam has a anti-schistosomal effect [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ro 11-3128; Ro 11-3128/002. CAS No. 58662-84-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-101725.
Mecoprop
Mecoprop is a herbicide [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 93-65-2. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-118126.
Medetomidine
Medetomidine is an orally active α2-adrenoceptor agonist ( K i : 1.08 nM). Medetomidine has sedative and analgesic effects. Medetomidine can cause peripheral vasoconstriction through the activation of α2 adrenoceptors on blood vessels [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 86347-14-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-17034.
Medetomidine hydrochloride
Medetomidine hydrochloride is an orally active α2-adrenoceptor agonist ( K i : 1.08 nM). Medetomidine hydrochloride has sedative and analgesic effects. Medetomidine hydrochloride can cause peripheral vasoconstriction through the activation of α2 adrenoceptors on blood vessels [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MPV785. CAS No. 86347-15-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-17034B.
MEDICA16
MEDICA16, an ATP-citrate lyase inhibitor, significantly reduces intracellular TG content in gastrocnemius muscle, and this reduction is accompanied by an increase in insulin sensitivity. MEDICA16 is a selective agonist for GPR40 as well as selective partial agonists for GPR120 [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 87272-20-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P1123.
Medicarpin
Medicarpin is a flavonoid isolated from Medicago sativa. Medicarpin induces apoptosis and overcome multidrug resistance in leukemia P388 cells by modulating P-gp-mediated efflux of agents [1]. Uses: Scientific research. Group: Natural products. CAS No. 32383-76-9. Pack Sizes: 5 mg. Product ID: HY-N3308.
Medifoxamine
Medifoxamine is a monoamine re-uptake inhibiting antidepressive agent which preferentially inhibits dopamine reuptake [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 32359-34-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119468.
Medroxalol
Medroxalol (RMI81968) is an orally active adrenergic receptor antagonist, blocks α- and β-adrenergic receptors. Medroxalol shows antihypertensive and vasodilating effects [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RMI81968. CAS No. 56290-94-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101656.
Medroxyprogesterone
Medroxyprogesterone (17α-Hydroxy-6α-methylprogesterone) is a synthetic human variant of progesterone that is a progesterone receptor agonist with oral activity. Medroxyprogesterone can induce cell proliferation through the PI3K/Akt signaling pathway. Medroxyprogesterone has an inhibitory effect on atherosclerosis in mice. The progesterone agonist activity of Medroxyprogesterone is less effective than Medroxyprogesterone acetate (HY-B0469) [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 17α-Hydroxy-6α-methylprogesterone; U8840. CAS No. 520-85-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-B0648.
Medroxyprogesterone acetate
Medroxyprogesterone acetate is a widely used synthetic steroid by its interaction with progesterone , androgen and glucocorticoid receptors [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Medroxyprogesterone 17-acetate; Farlutin. CAS No. 71-58-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-B0469.
Medroxyprogesterone-d3
Medroxyprogesterone-d 3 is the deuterium labeled Medroxyprogesterone. Medroxyprogesterone is a progestin, a synthetic variant of the human hormone progesterone and a potent progesterone receptor agonist. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: 17α-Hydroxy-6α-methylprogesterone-d3; U8840-d3. CAS No. 162462-69-3. Pack Sizes: 1 mg. Product ID: HY-B0648S.
Medroxyprogesterone (Standard)
Medroxyprogesterone (Standard) is the analytical standard of Medroxyprogesterone. This product is intended for research and analytical applications. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 17α-Hydroxy-6α-methylprogesterone(Standard); U8840 (Standard). CAS No. 520-85-4. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-B0648R.
Medrysone
Medrysone is a corticosteroid with potential for research on ocular inflammation in ophthalmology. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HMS; 6α-Methyl-11β-hydroxyprogesterone. CAS No. 2668-66-8. Pack Sizes: 10 mM * 1 mL; 25 mg. Product ID: HY-B1076.
Mefatinib
Mefatinib is a potent tyrosine kinase inhibitor with antineoplastic activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Mifanertinib dimaleate. CAS No. 1989592-50-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-152852A.
Mefatinib free base
Mefatinib free base is a potent tyrosine kinase inhibitor with antineoplastic activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Mifanertinib. CAS No. 1639014-72-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-152852.
Mefenamic acid
Mefenamic acid is a non-steroidal anti-inflammatory agent, acting as a competitive inhibitor of hCOX-1 and hCOX-2 , with IC 50 s of 40 nM and 3 μM for hCOX-1 and hCOX-2, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 61-68-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 5 g; 10 g. Product ID: HY-B0574.
Mefentrifluconazole
Mefentrifluconazole is a novel azole derivative and used as an agrochemical broad-spectrum antifungal agent. Mefentrifluconazole is a potent, selective and orally active fungal CYP51 ( K d = 0.5 nM) inhibitor, but shows less inhibitory activity on human aromatase ( IC 50 =0.92 μM) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1417782-03-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136063.
Mefloquine
Mefloquine (Mefloquin), an orally active and potent quinoline antimalarial agent, is an anti- SARS-CoV-2 entry inhibitor. Mefloquine is also a K + channel (KvQT1/minK) antagonist with an IC 50 of ~1 μM. Mefloquine can be used for malaria, systemic lupus erythematosus and cancer research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Mefloquin. CAS No. 53230-10-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17437.
Mefloquine hydrochloride
Mefloquine hydrochloride (Mefloquin hydrochloride), a quinoline antimalarial agent, is an anti- SARS-CoV-2 entry inhibitor. Mefloquine hydrochloride is also a K + channel (KvQT1/minK) antagonist with an IC 50 of ~1 μM. Mefloquine hydrochloride can be used for malaria, systemic lupus erythematosus and cancer research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Mefloquin hydrochloride. CAS No. 51773-92-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-17437A.
Mefluidide
Mefluidide is a potent inhibitor of KCS6 , CER60 and CER1 enzymes and can be used in herbicide research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MBR 12325. CAS No. 53780-34-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120803.
MEGA-10
MEGA-10 (N-Oxodecyl meglumine) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: N-Oxodecyl meglumine. CAS No. 85261-20-7. Pack Sizes: 100 mg; 500 mg; 1 g. Product ID: HY-W040217.
Megestrol
Megestrol is a synthetic progestin and used for the treatment of anorexia, cachexia, or an unexplained significant weight loss in patients with an acquired immunodeficiency syndrome diagnosis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3562-63-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B1834.
Megestrol acetate
Megestrol acetate is a synthetic and orally active progesteronal agent. Megestrol acetate is effective as an appetite stimulant for wasting syndromes such as cachexia. Megestrol acetate decreases nuclear and cytosol androgen receptors human BPH tissue. Megestrol acetate has the potential for HIV study and downregulates autophagic catabolic pathway [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 595-33-5. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-13676.
Megestrol acetate (Standard)
Megestrol acetate (Standard) is the analytical standard of Megestrol acetate. This product is intended for research and analytical applications. Megestrol acetate is a synthetic and orally active progesteronal agent. Megestrol acetate is effective as an appetite stimulant for wasting syndromes such as cachexia. Megestrol acetate decreases nuclear and cytosol androgen receptors human BPH tissue. Megestrol acetate has the potential for HIV study and downregulates autophagic catabolic pathway [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 595-33-5. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13676R.
Meglumine
Meglumine (Methylglucamine) is an orally active amino sugar derived from sorbitol. Meglumine has anti-inflammatory and antitumor activity. Meglumine is often used as an excipient in active molecules and with iodinated compounds in contrast agents such as meglumine and meglumine iodide [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Methylglucamine; Meglumin; Methylglucamin. CAS No. 6284-40-8. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-B0342.
Meglutol
Meglutol is a lipid-lowering agent. Meglutol can reduces cholesterol, triglycerides, serum β-lipoprotein, and phospholipids, and inhibits the activity of HMG-CoA reductase (a rate-limiting enzyme in cholesterol biosynthesis). Meglutol can induce significant lipid oxidative damage in brain tissue. It is promising for research in the field of cardiovascular diseases and metabolic diseases [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Dicrotalic acid; 3-Hydroxy-3-methylglutaric acid. CAS No. 503-49-1. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B1189.
MeIQx
MeIQx, a dietary aromatic amine, is mutagenic compound could be isolated from present in fried beef and beef extracts. MeIQx binds covalently to hemoglobin. MeIQx induces liver tumors [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline-2. CAS No. 77500-04-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-W355129.
MEISi-1
MEISi-1 is a homeodomain inhibitor of small molecule MEIS1 protein. MEISi-1 significantly inhibited the activity of luciferase reporter genes containing MEIS binding sites (TGACAG) and induced self-renewal of mouse and human HSCS in vitro and in vivo. MEISi-1 can be used for research in blood diseases, heart regeneration and cancer[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 446306-43-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134258.
MEK inhibitor
MEK inhibitor is a potent MEK inhibitor with antitumor potency. Uses: Scientific research. Group: Signaling pathways. CAS No. 334951-92-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-12202.
Melagatran
Melagatran is a direct and orally active inhibitor of thrombin , without interacting with any other enzymes in the coagulation cascade or fibrinolytic enzymes aside from thrombin. Melagatran does not require endogenous co-factors for its antithrombin effect and may help to alleviate some of the damaging effects of endotoxemia [1]. Melagatran has the potential to provide a rational approach in the prevention of arterial occlusion [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 159776-70-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129056.
Melamine
Melamine is an orally active inducer of Apoptosis. Melamine induces animal disease models. Melamine affects the activity of Sertoli cell and can be used for research on male reproductive function. Melamine also has neurotoxicity and nephrotoxicity. Melamine induces cognitive impairment and acute kidney injury models. Melamine can also be used to induce bladder cancer and urinary stone models [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Natural products. CAS No. 108-78-1. Pack Sizes: 10 mM * 1 mL; 5 g. Product ID: HY-Y1117.
Melamine-15N3,13C3
Melamine- 15 N 3 , 13 C 3 is a 13 C- and 15 N-labeled Melamine (HY-Y1117). Melamine is a metabolite of cyromazine. Melamine is a intermediate for the synthesis of melamine resin and plastic materials [1] [2]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 1246816-14-7. Pack Sizes: 1 mg. Product ID: HY-Y1117S2.
Melanin
Melanin is a unique pigment with myriad functions. It is multifunctional, providing defense against environmental stresses such as ultraviolet (UV) light, oxidizing agents and ionizing radiation. Uses: Scientific research. Group: Natural products. CAS No. 8049-97-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113485.