MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| MARK-IN-4 | MARK-IN-4 is a potent microtubule affinity regulating kinase (MARK) inhibitor with an IC50 of 1 nM. Inhibition of microtubule affinity regulating kinase (MARK) represents a potentially attractive means of arresting neurofibrillary tangle pathology in Alzheimer's disease[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1990492-86-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-112266. |  |
| (±)-Marmesin | (±)-Marmesin is a good precursor of the linear furanocoumarins. (±)-Marmesin derivatives have high degree of acetylcholinesterase inhibitory property [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 13710-70-8. Pack Sizes: 1 mg. Product ID: HY-N2176A. | |
| Maropitant | Maropitant is a selective and orally active neurokinin (NK1) receptor antagonist. Maropitant acts by blocking the binding of substance P within the emetic center and the chemoreceptor trigger zone (CRTZ). Maropitant is highly effective in preventing vomiting [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 147116-67-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10053. | |
| Marrubiin | Marrubiin, isolated from Marrubium vulgare , exhibits vasorelaxant and antioedematogenic activity. Marrubiin alleviates diabetic symptoms in animals [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 465-92-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N6995. | |
| Marstacimab | Marstacimab (PF-06741086) is an anti-tissue factor pathway inhibitor ( TFPI ) monoclonal antibody. Marstacimab can be used for the research of hemophilia [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: PF-06741086. CAS No. 1985638-39-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99725. | |
| MART-1 (26-35) (human) | MART-1 (26-35) (human) is amino acid residue 26 to 35 of MART-1 protein. Uses: Scientific research. Group: Peptides. CAS No. 156251-01-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0138. | |
| Masitinib | Masitinib (AB1010) is a potent, orally bioavailable, and selective inhibitor of c-Kit ( IC 50 =200 nM for human recombinant c-Kit). It also inhibits PDGFRα/β ( IC 50 s=540/800 nM), Lyn ( IC 50 = 510 nM for LynB), Lck , and, to a lesser extent, FGFR3 and FAK. Masitinib (AB1010) has anti-proliferative, pro-apoptotic activity and low toxicity [1] [2] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AB1010. CAS No. 790299-79-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10209. | |
| Masitinib mesylate | Masitinib mesylate (AB-1010 mesylate) is a potent, orally bioavailable, and selective inhibitor of c-Kit ( IC 50 =200 nM for human recombinant c-Kit). It also inhibits PDGFRα/β ( IC 50 s=540/800 nM), Lyn ( IC 50 = 510 nM for LynB), Lck , and, to a lesser extent, FGFR3 and FAK. Masitinib mesylate (AB-1010 mesylate) has anti-proliferative, pro-apoptotic activity and low toxicity [1] [2] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AB-1010 mesylate. CAS No. 1048007-93-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10209A. | |
| Maslinic acid | Maslinic acid can inhibit the DNA-binding activity of NF-κB p65 and abolish the phosphorylation of IκB-α , which is required for p65 activation. Uses: Scientific research. Group: Natural products. Alternative Names: Crategolic acid; 2α-Hydroxyoleanolic acid. CAS No. 4373-41-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-N0629. | |
| MASM7 | MASM7 is a mitofusin activator, and can achieve mitochondrial fusion via mitofusins. MASM7 can increase Mito AR with an EC50 value of 75 nM in MEFs in concentration-responsively, and can promote mitochondrial fusion by directly activating MFN2 or MFN. MASM7 also demonstrates direct binding to the HR2 domain of MFN2 with Kd value of 1.1 ?M[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 920868-45-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-W187305. | |
| Masofaniten | Masofaniten (Androgen receptor-IN-2) is a potent and orally active androgen receptor inhibitor. Masofaniten has antitumor activity against prostate cancer [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Androgen receptor-IN-2. CAS No. 2416716-62-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136582. | |
| Masoprocol | Masoprocol (meso-Nordihydroguaiaretic acid) is a potent and orally active lipoxygenase inhibitor. Masoprocol shows antihyperglycemic activity. Masoprocol decreases the glucose concentration and hepatic triglyceride in vivo. Masoprocol has the potential for the research of type II diabetes [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: meso-Nordihydroguaiaretic acid; meso-NDGA. CAS No. 27686-84-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-109500. | |
| Massoia lactone | Massoia lactone ((±)-Massoia lactone) is a coconut and creamy fragrant compound mianly isolated from Cryptocarya massoy. Massoia lactone is also a fragrant biosurfactant produced by a fungus Aureobasidium pullulans [1]. Uses: Scientific research. Group: Natural products. Alternative Names: (±)-Massoia lactone. CAS No. 54814-64-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 5 g; 10 g; 25 g. Product ID: HY-N7435. | |
| Mastoparan | Mastoparan, a tetradecapeptide which is a component of wasp venom, stimulates release of prolactin from cultured rat anterior pituitary cells. Uses: Scientific research. Group: Peptides. CAS No. 72093-21-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0246. | |
| Mastoparan X | Mastoparan X is a GTP-binding regulatory protein ( G protein )-activating peptide, and a tetradecapeptide from wasp venom. Mastoparan X acts function by the direct activation of G protein that couple to phospholipase C to cause secretion from various kinds of cells [1]. Uses: Scientific research. Group: Peptides. CAS No. 72093-22-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P2705. | |
| Masupirdine mesylate | Masupirdine mesylate (SUVN-502 mesylate) is a potent, selective, orally bioavailable, and brain penetrant 5-HT6 receptor antagonist ( K i of 2.04 nM for human 5-HT6 receptor). Masupirdine mesylate (SUVN-502 mesylate) shows high selectivity over 5-HT2A receptor and other 100 target sites, and has potential for treatment of Alzheimer's disease [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SUVN-502 mesylate. CAS No. 1791396-46-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109118A. | |
| MAT2A inhibitor 2 | MAT2A inhibitor 2 is an inhibitor of methionine adenosine transferase 2A ( MAT2A ) with oral activity. MAT2A inhibitor 2 can be used in osteoporosis study [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 13299-99-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112569. | |
| Matairesinol | Matairesinol confers anti-allergic effects in an allergic dermatitis mouse model. DfE-induced changes in IL-4 and IFN-γ mRNA expression in the ears of NC/Nga mice were reversed by matairesinol application [1]. Uses: Scientific research. Group: Natural products. CAS No. 580-72-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N3312. | |
| Matrine | Matrine (Matridin-15-one) is an alkaloid found in plants from the Sophora genus that can act as a kappa opioid receptor and u-receptor agonist. Matrine has a variety of pharmacological effects, including anti-cancer, anti-oxidative stress, anti-inflammation and anti-apoptosis effects. Matrine is potential in the research of disease like human non-small cell lung cancer, hepatoma, papillary thyroid cancer and acute kidney injury (AKI) [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. Alternative Names: Matridin-15-one; Vegard; α-Matrine. CAS No. 519-02-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg. Product ID: HY-N0164. | |
| Matriptase-IN-2 | Matriptase-IN-2 (compound 432) is a potent Matriptase inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1268874-09-4. Pack Sizes: 5 mg. Product ID: HY-W783268A. | |
| Matuzumab | Matuzumab (EMD 72000) is a humanized anti- EGFR monoclonal antibody that blocks EGFR activation and downstream signaling, inhibits tumor growth [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: EMD 72000. CAS No. 339186-68-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9969. | |
| Mavacamten | Mavacamten (MYK461) is an orally active modulator of cardiac myosin , with IC 50 s of 490, 711 nM for bovine cardiac and human cardiac, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MYK461; SAR439152. CAS No. 1642288-47-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109037. | |
| Mavacamten-d5 | Mavacamten-d5 (MYK461-d5; SAR439152-d5) is deuterium labeled Mavacamten (HY-109037). Mavacamten (MYK461) is an orally active modulator of cardiac myosin, with IC50s of 490, 711 nM for bovine cardiac and human cardiac, respectively. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: MYK461-d5; SAR439152-d5. CAS No. 2453251-00-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-109037S3. | |
| Mavacoxib | Mavacoxib is a selective, oral long-acting cyclooxygenase-2 (COX-2) inhibitor and a long-acting non-steroidal anti-inflammatory drug (NSAID). Mavacoxib is used to treat pain and inflammation associated with degenerative joint disease in dogs [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 170569-88-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-119447. | |
| Mavatrep | Mavatrep (JNJ-39439335) is an orally active, selective and potent TRPV1 antagonist with high affinity for hTRPV1 channels (Ki=6.5 nM). Mavatrep antagonizes capsaicin-induced Ca2+ influx with an IC50 value of 4.6 nM. Mavatrep can be used in some studies of neuropathic pain[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: JNJ-39439335. CAS No. 956274-94-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16935. | |
| Mavelertinib | Mavelertinib is a selective, orally available and irreversible EGFR tyrosine kinase inhibitor (EGFR TKI), with IC50s of 5, 4, 12 and 3 nM for Del, L858R, and double mutants T790M/L858R and T790M/Del, respectively. Mavelertinib can be used for the research of non-small-cell lung cancer (NSCLC)[1][2][3][4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PF-06747775. CAS No. 1776112-90-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12972. | |
| Mavoglurant | Mavoglurant (AFQ056) is a potent, selective, non-competitive and orally active mGluR5 antagonist, with an IC 50 of 30 nM. Mavoglurant shows a >300 fold selectivity for the mGluR5 over all targets (238) tested. Mavoglurant can be used for the research of Fragile X syndrome (FXS), and L-dopa induced dyskinesias in Parkinson's disease [1] [1] [2]. Mavoglurant is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AFQ056. CAS No. 543906-09-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15257. | |
| Mavoglurant racemate | Mavoglurant racemate (AFQ-056 racemate) is the racemate of Mavoglurant. Mavoglurant is a novel, non-competitive mGlu5 receptor antagonist [1]. Mavoglurant (racemate) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AFQ-056 racemate. CAS No. 1636881-61-2. Pack Sizes: 2 mg; 5 mg. Product ID: HY-15257A. | |
| Mavorixafor hydrochloride | Mavorixafor (AMD-070) hydrochloride is a potent, selective and orally available CXCR4 antagonist, with an IC 50 value of 13 nM against CXCR4 125 I-SDF binding. Mavorixafor hydrochloride also inhibits the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells and PBMCs with an IC 50 of 1 nM and 9 nM, respectively. Mavorixafor hydrochloride can be used for the study of WHIM syndrome [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AMD-070 hydrochloride; AMD-11070 hydrochloride. CAS No. 880549-30-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-50101C. | |
| Mavorixafor trihydrochloride | Mavorixafor trihydrochloride (AMD-070 trihydrochloride) is a potent, selective and orally available CXCR4 antagonist, with an IC50 value of 13 nM against CXCR4 125I-SDF binding, and also inhibits the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells and PBMCs with an IC50 of 1 and 9 nM, respectively.Mavorixafor trihydrochloride can be used for the study of WHIM syndrome[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AMD-070 trihydrochloride; AMD-11070 trihydrochloride. CAS No. 2309699-17-8. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-50101A. | |
| Mavrilimumab | Mavrilimumab (CAM 3001) is a monoclonal antibody that binds to the α subunit of the granulocyte-macrophage colony stimulating factor ( GM-CSF ) receptor and blocks intracellular signalling downstream of GM-CSF. GM-CSF might be a mediator of the hyperactive inflammatory response associated with respiratory failure and death [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: CAM 3001. CAS No. 1085337-57-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99031. | |
| MAX-40279 | MAX-40279 is a dual and potent inhibitor of FLT3 kinase and FGFR kinase. MAX-40279 has the potential for the research of acute myelogenous leukemia (AML) (extracted from patent WO2021180032) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2070931-57-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145723. | |
| Maxacalcitol | Maxacalcitol (22-Oxacalcitriol), a vitamin D3 (HY-15398) analog, is an orally active VDR agonist. Maxacalcitol has a limited calcemic effect. Maxacalcitol has the potential for psoriasis and hyperparathyroidism research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 22-Oxacalcitriol. CAS No. 103909-75-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-32339. | |
| Maytansine | Maytansine is a highly potent microtubule-targeted compound that induces mitotic arrest and kills tumor cells at subnanomolar concentrations [1]. Uses: Scientific research. Group: Natural products. Alternative Names: NSC 153858. CAS No. 35846-53-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-13674. | |
| MAZ51 | MAZ51 is a selective inhibitor of VEGFR-3 (Flt-4) tyrosine kinase. MAZ51 inhibits VEGF-C-induced activation of VEGFR-3 without blocking VEGF-C-mediated stimulation of VEGFR2. MAZ51 had no effect on ligand-induced autophosphorylation of EGFR, IGF-1R and PDGFR?. MAZ51 blocks proliferation and induces apoptosis in a wide variety of tumor cells. Antitumor activity[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 163655-37-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116624. | |
| Mazdutide | Mazdutide (IBI-362; LY-3305677) is a long-acting synthetic oxyntomodulin analog. Mazdutide is also a co-agonist of glucagon-like peptide ( GLP-1R ) and glucagon receptor ( GCGR ). Mazdutide binds human and mouse GCGR ( K i : 17.7 nM and 15.9 nM, respectively) and GLP-1R ( K i : 28.6 nM and 25.1 nM, respectively) and stimulates insulin secretion from mouse islets ( EC 50 : 5.2 nM). Mazdutide is used in studies of obesity and type 2 diabetes (T2D) [1] [2] [3]. Uses: Scientific research. Group: Peptides. Alternative Names: IBI-362; LY-3305677; OXM-3. CAS No. 2259884-03-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P3375. | |
| Mazisotine | SSTR4 agonist-1 (Compound 47) is a selective agonist for somatostatin receptor subtype 4 ( SSTR4 ) with an EC 50 of 4.7 nM. SSTR4 agonist-1 reveals a half-life > 130 minutes in human liver microsomes [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1638588-92-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139347. | |
| MB05032 | MB05032 is a special and efficacious gluconeogenesis inhibitor targeted the AMP binding site of fructose 1,6-bisphosphatase (FBPase) with an IC50 value of 16 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 261365-11-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16307. | |
| MB710 | MB710, an aminobenzothiazole derivative, is a stabilizer of oncogenic p53 mutation Y220C. MB710 binds tightly to the Y220C pocket and stabilizes p53-Y220C , with a K d of 4.1?μM. MB710 shows anticancer activity in p53-Y220C cell lines [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2230044-57-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-120373. | |
| MBD | MBD (7-(p-Methoxybenzylamino)-4-nitrobenz-2,1,3-oxadiazole), a new fluorescent probe for protein and nucleoprotein conformation, is applied to bacterial ribosomes and to bovine trypsinogen and trypsin. MBD is strongly fluorescent upon binding to a hydrophobic area of a macromolecule [1] [2]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: 7-(p-Methoxybenzylamino)-4-nitrobenz-2,1,3-oxadiazole. CAS No. 33984-50-8. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-141667. | |
| MBQ-167 | MBQ-167 is a dual Rac/Cdc42 inhibitor, with IC50s of 103 nM for Rac 1/2/3 and 78 nM for Cdc42 in MDA-MB-231 cells, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 2097938-73-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-112842. | |
| MBX-2982 | MBX-2982 is a selective, orally-available G protein-coupled receptor 119 ( GPR119 ) agonist. Uses: Scientific research. Group: Signaling pathways. CAS No. 1037792-44-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15291. | |
| MC1568 | MC1568 is a selective class II (IIa) histone deacetylas (HDAC II) inhibitor, used for cancer research. Uses: Scientific research. Group: Signaling pathways. CAS No. 852475-26-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16914. | |
| MC70 | MC70 is a potent and non-selective P-glycoprotein (P-gp) inhibitor with an EC 50 of 0.69 μM. MC70 is an ABC transporters inhibitor and anticancer agent. MC70 interacts with ABCB1, ABCG2 and ABCC1 [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1031367-64-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113805. | |
| MCA | MCA is a coumarin derivative. MCA quantitates platelet-activating factor by high-performance liquid chromatography with fluorescent detection. MCA can modify FRET peptide substrates for analyzing protease activities [1] [2]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 62935-72-2. Pack Sizes: 100 mg; 250 mg; 500 mg. Product ID: HY-W027544. | |
| MC-AAA-NHCH2OCH2COOH | MC-AAA-NHCH2OCH2COOH (compound 20) is a cleavable ADC linker that is used for making antibody-drug conjugate (ADC) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2414594-28-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132159. | |
| Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 | Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 (FS-6) is a fluorescent peptide that is a quenched MMP peptide substrate. Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 can be used for real-time quantification of MMP enzymatic activity. Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 is an elongated peptide of MMP substrate (FS-1) and is active against collagenases (MMP-1, MMP-8, MMP-13 ) and MT1-MMP with higher specificity constants than FS-1[1]. (Ex/Em=325 nm/400 nm). Uses: Scientific research. Group: Peptides. Alternative Names: Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2. CAS No. 720710-69-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P4931. | |
| Mca-SEVNLDAEFK(Dnp)-NH2 | Mca-SEVNLDAEFK(Dnp)-NH2 contains a highly fluorescent 7-methoxycoumarin group that is efficiently quenched by resonance energy transfer to the 2,4-dinitrophenyl group. It can be used to measure the activities of peptidases that are capable of cleaving an amide bond between the fluorescent group and the quencher group, causing an increase in fluorescence, such as can be used to measure the activity of BACE-1 [1]. Uses: Scientific research. Group: Peptides. CAS No. 1802078-32-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P4920. | |
| MCB-613 | MCB-613 is a potent Steroid receptor coactivator SRC small molecule stimulator (SMS), super-stimulates SRCs transcriptional activity. MCB-613 increases SRCs interactions with other coactivators and markedly induces ER stress coupled to the generation of reactive oxygen species ( ROS ). MCB-613 is a SMS that target oncogenes can be exploited as anti-cancer agents by over-stimulating the SRC oncogenic program [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1162656-22-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19625. | |
| MC-betaglucuronide-MMAE-1 | MC-betaglucuronide-MMAE-1 is a agent-linker conjugate for ADC with potent antitumor activity by using MMAE (a tubulin polymerization inhibitor), linked via the cleavable ADC linker MC-betaglucuronide. Uses: Scientific research. Group: Signaling pathways. CAS No. 1703778-92-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-136317. | |
| MCC | MCC is non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as MCC-DM1 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 104676-09-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132251. | |
| MCC950 | MCC950 (CP-456773; CRID3) is a potent and selective NLRP3 inhibitor with IC 50 s of 7.5 and 8.1 nM in BMDMs and HMDMs, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CP-456773; CRID3. CAS No. 210826-40-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12815. | |
| MCC950 sodium | MCC950 sodium (CP-456773 sodium; CRID3 sodium salt) is a potent, selective NLRP3 inhibitor with IC 50 s of 7.5 and 8.1 nM in BMDMs and HMDMs, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CP-456773 sodium; CRID3 sodium salt. CAS No. 256373-96-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-12815A. | |
| MC-DOXHZN hydrochloride | MC-DOXHZN ((E/Z)-Aldoxorubicin) hydrochloride is an albumin-binding proagent of Doxorubicin (DNA topoisomerase II inhibitor), with acid-sensitive properties [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (E/Z)-Aldoxorubicin hydrochloride; Doxorubicin(6-maleimidocaproyl)hydrazone hydrochloride. CAS No. 480998-12-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-16261B. | |
| MC-GGFG-Exatecan | MC-GGFG-Exatecan (MC-GGFG-DX8951) is a agent-linker conjugate for ADC. MC-GGFG-Exatecan is a DX8951 (a DNA topoisomerase I inhibitor) derivative with protease cleavable MC-GGFG linker. MC-GGFG-Exatecan shows antitumor activity and can be used to prepare DX8951 antibody conjugate (ADC)[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MC-GGFG-DX8951. CAS No. 1600418-29-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114233. | |
| MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH | MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1599440-25-1. Pack Sizes: 50 mg; 100 mg. Product ID: HY-131990. | |
| MCH(human, mouse, rat) TFA | MCH (human, mouse, rat) TFA is a potent peptide agonist of MCH-R and exhibits binding IC50 values of 0.3nM and 1.5 nM for MCH1R and MCH2R, respectively. MCH (human, mouse, rat) is a highly sensitive to MCH-2R in a CHO cell line and monitoring mobilization of intracellular calcium with FLIPR, exhibits functional activation EC50 values of 3.9?nM and 0.1nM for human MCH-1R and MCH-2R, respectively[1]. Uses: Scientific research. Group: Peptides. Alternative Names: Melanin-concentrating hormone(human, mouse, rat) TFA. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1205A. | |
| MCL-1/BCL-2-IN-2 | MCL-1/BCL-2-IN-2 (Compound 6) is a potent and selective Mcl-1 and Bcl-2 dual inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2163793-44-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-129700. | |
| MCL-1/BCL-2-IN-3 | MCL-1/BCL-2-IN-3 (Compound 2) is a potent and selective Mcl-1 and Bcl-2 dual inhibitor with IC 50 s of 5.95 and 4.78 μM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2163793-55-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129701. | |
| Mcl1-IN-1 | Mcl1-IN-1 is an inhibitor of myeloid cell factor 1 ( Mcl-1 ) ( IC 50 =2.4 μM). Uses: Scientific research. Group: Signaling pathways. CAS No. 713492-66-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16669. | |
| MCLA hydrochloride | MCLA hydrochloride is a chemiluminescent reagent which can be used to quantify aqueous concentrations of superoxide. Uses: Scientific research. Group: Fluorescent dye. CAS No. 128322-44-1. Pack Sizes: 5 mg. Product ID: HY-W013275. | |
| Mc-MMAE | Mc-MMAE is a protective group (maleimidocaproyl)-conjugated monomethyl auristatin E (MMAE), which is a potent tubulin inhibitor. Mc-MMAE is a agent-linker conjugate for ADC. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Maleimidocaproyl-monomethylauristatin E. CAS No. 863971-24-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15741. | |
| McMMAF | McMMAF (Maleimidocaproyl monomethylauristatin F) is an active molecule linker for ADC, made by coupling the powerful microtubule inhibitor Monomethyl auristatin F (MMAF) with the protecting group maleimidocaproyl. McMMAF can be conjugated with anti-BCMA antibodies to form J6M0-mcMMAF, promoting apoptosis and inhibiting tumor growth[1][2][3][4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Maleimidocaproyl monomethylauristatin F. CAS No. 863971-19-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15578. | |
| McN-A-343 | McN-A-343 is a selective M1 muscarinic agonist that stimulates muscarinic transmission in sympathetic ganglia. McN-A-343 reduces inflammation and oxidative stress in an experimental model of ulcerative colitis [1] [2]. McN-A-343 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 55-45-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107648. | |
| MCOPPB trihydrochloride | MCOPPB trihydrochloride is a nociceptin receptor agonist with pKi of 10. Uses: Scientific research. Group: Signaling pathways. CAS No. 1108147-88-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13101. | |
| m-Coumaric acid | m-Coumaric acid is a polyphenol metabolite from caffeic acid, formed by the gut microflora and the amount in human biofluids is diet-dependant. Uses: Scientific research. Group: Natural products. CAS No. 588-30-7. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-113357. | |
| MCPA | MCPA is a phenoxy herbicide, and widely used to control annual and perennial broad leaved weeds, including poppy, thistles and docks, in crops such as cereals, rice, linseed, flax, grassland and turf [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 94-74-6. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-B0859. | |
| Mc-PEG4-Val-Ala-PAB-Exatecan | Mc-PEG4-Val-Ala-PAB-Exatecan is a Drug-linker conjugate for ADC. Mc-PEG4-Val-Ala-PAB-Exatecan contains the ADC linker (Mc-PEG4-Val-Ala-PAB) and a DNA topoisomerase I inhibitor Exatecan (HY-13631)[1]. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 5 mg; 10 mg. Product ID: HY-171580. | |
| MCT-IN-1 | MCT-IN-1 (compound 2) is a potent inhibitor of monocarboxylate transporter (MCT), with the IC50 of 9 nM and 14 nM for MCT1 and MCT4, respectively[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1685273-57-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-150314. | |
| MCTR3 | MCTR3 is a potent cytokine of pro-resolving mediating maresin conjugates in tissue regeneration (MCTR), which reduces the inflammatory response and promotes the tissue regeneration. MCTR3 exhibits potency in ameliorating LPS-induced acute lung injury and arthritis [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1784701-63-8. Pack Sizes: 10 μg (215.69 μM * 100 μL in Ethanol)); 25 μg (215.69 μM * 250 μL in Ethanol). Product ID: HY-125516. | |
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