MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| PAWI-2 | PAWI-2 is a p53 -Activator and Wnt Inhibitor. PAWI-2 inhibits β3-KRAS signaling independent of KRAS. PAWI-2 selectively inhibits phosphorylation of TBK1. PAWI-2 activates apoptosis (activation of caspase-3/7), and induces PARP cleavage. PAWI-2 promotes optineurin translocation into the nucleus and causes G2/M arrest. PAWI-2 reverses cancer stemness and overcomes drug resistance in an integrin β3 KRAS-dependent human pancreatic cancer stem cells (hPCSCs). PAWI-2 inhibits growth of tumors from hPCSCs in orthopic xenograft mice model [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1448427-02-8. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-123929. |  |
| Paxalisib | Paxalisib (GDC-0084) is a brain penetrant inhibitor of PI3K and mTOR , with K i s of 2 nM, 46 nM, 3 nM, 10 nM and 70 nM for PI3Kα PI3Kβ, PI3Kδ, PI3Kγ and mTOR, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GDC-0084. CAS No. 1382979-44-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-19962. | |
| Pazopanib | Pazopanib (GW786034) is a novel multi-target inhibitor of VEGFR1 , VEGFR2 , VEGFR3 , PDGFRβ , c-Kit , FGFR1 , and c-Fms with IC 50 s of 10, 30, 47, 84, 74, 140 and 146 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GW786034. CAS No. 444731-52-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-10208. | |
| Pazopanib Hydrochloride | Pazopanib Hydrochloride (GW786034 Hydrochloride) is a novel multi-target inhibitor of VEGFR1 , VEGFR2 , VEGFR3 , PDGFRβ , c-Kit , FGFR1 , and c-Fms with an IC 50 of 10, 30, 47, 84, 74, 140 and 146 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GW786034 Hydrochloride. CAS No. 635702-64-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-12009. | |
| Pazufloxacin mesylate | Pazufloxacin (T-3761) mesylate is a fluoroquinolone antibiotic. Uses: Scientific research. Group: Signaling pathways. Alternative Names: T-3762; Pazufloxacin methanesulfonate; Pazufloxacin mesilate. CAS No. 163680-77-1. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0724A. | |
| PB1 | PB1 is a potent intracellular disulfide reducing agent with several advantages including good cell permeability, the ability to form a high intracellular concentration gradient, and stability. PB1 is a borane-protected TCEP (tris(2-carboxyethyl)phosphine) analogue. PB1 increases retinal ganglion cells survival after axotomy in vitro at nanomolar and picomolar concentrations. PB1 can be used for the research of neuroprotective [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 188714-28-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138648. | |
| PB2 | PB2 is a tris(2-carboxyethyl)phosphine (TCEP) analogue increasing retinal ganglion (RGCs) cells survival after axotomy in vitro at nanomolar and picomolar concentrations. PB2 is substantially more permeable than TCEP. PB2, as a reducing agent, is highly neuroprotective for RGCs [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 914940-24-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138649. | |
| PB28 dihydrochloride | PB28 dihydrochloride, a cyclohexylpiperazine derivative, is a high affinity and selective sigma 2 (σ2) receptor agonist with a K i of 0.68 nM. PB28 dihydrochloride is also a σ1 antagonist with a K i of 0.38 nM. PB28 dihydrochloride is less affinity for other receptors. PB28 dihydrochloride inhibits electrically evoked twitch in guinea pig bladder and ileum with EC 50 values of 2.62 μM and 3.96 μM, respectively. PB28 dihydrochloride can modulate SARS-CoV-2-human protein-protein interaction. PB28 dihydrochloride induces caspase-independent apoptosis and has antitumor activity [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 172907-03-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108511. | |
| PBFI-AM | PBFI-AM is a useful tool to determine intracellular K + content [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 124549-23-1. Pack Sizes: 1 mg. Product ID: HY-136872. | |
| PBIT | PBIT is a specific inhibitor of the Jumonji AT-rich Interactive Domain 1 ( JARID1 ) enzymes. PBIT inhibits JARID1B ( KDM5B or PLU1 ) histone demethylase with an IC 50 of about 3 μM. PBIT also inhibits JARID1A and JARID1C with IC 50 s of 6 μM and 4.9 μM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2514-30-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101451. | |
| PBP10 | PBP10 is a cell permeable and selective gelsolin-derived peptide inhibitor of formyl peptide receptor 2 (FPR2) over FPR1 [1]. PBP10 is a 10-AA peptide with rhodamine conjugated at its N terminus, exerts bactericidal activity against gram-positive and gram-negative bacteria and limits microbial-induced inflammatory effects [2]. Uses: Scientific research. Group: Peptides. CAS No. 794466-43-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1116. | |
| PBR28 | PBR28 is an TSPO modulator, which can be used for prevention research of Pulmonary Arterial Hypertension (PAH). PBR28 can be used to trace 18 KDa transporter (TSPO) by adding radioactive labeling, which plays an important role in brain positron emission tomography (PET) imaging studies [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 253307-65-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153248. | |
| PBT434 mesylate | PBT434 methanesulfonate is a potent, orally active and cross the blood-brain barrier α-synuclein aggregation inhibitor. PBT434 methanesulfonate can be used as a iron chelator and modulates transcellular iron trafficking. PBT434 methanesulfonate inhibits iron-mediated redox activity and iron-mediated aggregation of α-synuclein. PBT434 methanesulfonate prevents the loss of substantia nigra pars compacta neurons (SNpc). PBT434 methanesulfonate has the potential for the research of Parkinsons disease (PD) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ATH434 mesylate. CAS No. 2387898-69-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-120475A. | |
| PC945 | PC945, a potent, long-acting antifungal triazole, possesses activity against a broad range of both azole-susceptible and azole-resistant strains of Aspergillus fumigatus. PC945 is also a potent, tightly binding inhibitor of A. fumigatus sterol 14α-demethylase activity, CYP51A and CYP51B , with IC 50 s of 0.23 μM and 0.22 μM, respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1931946-73-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-117766. | |
| PCAF-IN-1 | PCAF-IN-1 is a highly selective PCAF inhibitor. PCAF-IN-1 is a antitumor agents, which can be used in tumor research research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2439194-86-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147894. | |
| PC-Biotin-PEG4-NHS carbonate | PC-Biotin-PEG4-NHS carbonate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2055198-03-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-140135. | |
| PC DBCO-PEG4-NHS ester | PC DBCO-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs [1]. PC DBCO-PEG4-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 2055025-02-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-138756. | |
| PCI-34051 | PCI-34051 is a potent and selective HDAC8 inhibitor with IC 50 of 10 nM, with >200-fold selectivity over the other HDAC isoforms. Uses: Scientific research. Group: Signaling pathways. CAS No. 950762-95-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15224. | |
| p-Coumaric acid | p-Coumaric acid (trans-4-Hydroxycinnamic acid) is an isomer of cinnamic acid with oral activity. p-Coumaric acid inhibits cell proliferation and promotes apoptosis. p-Coumaric acid has antibacterial , anti-inflammatory, antioxidant and anti-tumor activities [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: trans-4-Hydroxycinnamic acid. CAS No. 501-98-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 1 g. Product ID: HY-N0351. | |
| PCPA methyl ester hydrochloride | PCPA methyl ester hydrochloride (4-Chloro-DL-phenylalanine methyl ester hydrochloride), a reversible tryptophan hydroxylase inhibitor, is a serotonin (5-HT) synthesis inhibitor. PCPA methyl ester hydrochloride crosses the blood brain barrier and reduces 5-HT central availability [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 4-Chloro-DL-phenylalanine methyl ester hydrochloride. CAS No. 14173-40-1. Pack Sizes: 10 mM * 1 mL; 1 g. Product ID: HY-101456. | |
| p-Cresol glucuronide | p-Cresol glucuronide, a metabolite of p-cresol, is a prototype protein-bound uremic toxin. p-Cresol glucuronide is associated with chronic kidney disease (CKD) [1]. Uses: Scientific research. Group: Natural products. CAS No. 17680-99-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-W416250. | |
| p-Cresyl sulfate potassium | p-Cresyl sulfate potassium is a uremic toxin that binds to a prototype protein. p-Cresyl sulfate potassium activates the JNK and p38 MAPK signaling pathways. p-Cresyl sulfate potassium has pro-inflammatory activity [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: p-Tolyl sulfate potassium. CAS No. 91978-69-7. Pack Sizes: 10 mM * 1 mL; 50 mg. Product ID: HY-111431A. | |
| PCS1055 | PCS1055 is a selective and competitive antagonist for muscarinic M4 receptor with an IC 50 of 18.1 nM and a K d of 5.72 nM. PCS1055 inhibits radioligand [ 3 H]-NMS binding to the M4 receptor with a K i of 6.5 nM. PCS1055 is also an inhibitor for AChE with IC 50 of 22 nM and 120 nM for electric eel and human AChE, respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 357173-55-8. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-122203A. | |
| PCS1055 dihydrochloride | PCS1055 dihydrochloride is a potent, selective and competitive muscarinic M4 receptor antagonist with an IC 50 of 18.1 nM and a K d of 5.72 nM. PCS1055 dihydrochloride inhibits radioligand [ 3 H]-NMS binding to the M4 receptor with a K i of 6.5 nM. PCS1055 dihydrochloride exhibits >100-fold selectivity over M1-, M3-, and M5-receptors and 30-fold selectivity at the M2 receptor. PCS1055 dihydrochloride is also a potent AChE inhibitor with IC 50 s of 22 nM and 120 nM for electric eel and human AChE , respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 361979-40-0. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-122203. | |
| PCSK9-IN-11 | PCSK9-IN-11 (compound 5r) is a potent and orally active PCSK9 inhibitor. PCSK9-IN-11 exhibits PCSK9 transcriptional inhibitory activity in HepG2 cells, with an IC 50 of 5.7 μM. PCSK9-IN-11 increases LDL receptor (LDLR) protein level. PCSK9-IN-11 can be used for atherosclerosis research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2882035-56-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-152223. | |
| PCSK9-IN-23 | PCSK9-IN-23 (compound 5C) is a potent PCSK9 inhibitor. PCSK9-IN-23 blocks PCSK9 secretion from HepG2 cells, significantly increases LDL receptor (LDLR) expression [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2115700-96-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-157434. | |
| PD0176078 | PD0176078 is a newly found N-type Calcium channel blocker. Uses: Scientific research. Group: Signaling pathways. CAS No. 248922-46-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-U00236. | |
| PD 102807 | PD 102807 is a M4 muscarinic receptor antagonist with an IC 50 of 90.7 nM. PD 102807 inhibits M1, M2, M3, M5 muscarinic receptor with IC 50 s of 6558.7, 3440.7, 950.0, and 7411.7 nM, respectively [1]. Antidyskinetic effect. Uses: Scientific research. Group: Signaling pathways. CAS No. 23062-91-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-107646. | |
| PD 123319 ditrifluoroacetate | PD 123319 (ditrifluoroacetate) is a potent, selective AT2 angiotensin II receptor antagonist with IC 50 of 34 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 136676-91-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-10259A. | |
| (+)-PD 128907 hydrochloride | (+)-PD 128907 hydrochloride is a selective dopamine D 2 /D 3 receptor agonist, with K i s of 1.7, 0.84 nM for human and rat D 3 receptors, 179, 770 n M for human and rat D 3 receptors, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 300576-59-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-110000. | |
| PD 128907 hydrochloride | PD 128907 (hydrochloride) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 112960-16-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-100539A. | |
| PD150606 | PD 150606 is a selective, cell-permeable non-peptide calpain inhibitor with K i values of 0.21 μM and 0.37 μM for μ- and m-calpains respectively, which is neuroprotective [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 179528-45-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100529. | |
| PD153035 | PD153035 (SU-5271; AG1517; ZM 252868) is a potent EGFR inhibitor with K i and IC 50 of 6 and 25 pM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SU-5271; AG1517; ZM 252868. CAS No. 153436-54-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-14346. | |
| PD153035 Hydrochloride | PD153035 Hydrochloride (SU-5271 Hydrochloride) is a potent EGFR inhibitor with K i and IC 50 of 6 and 25 pM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SU-5271 Hydrochloride; AG1517 Hydrochloride; ZM 252868 Hydrochloride. CAS No. 183322-45-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12013. | |
| PD-156707 | PD-156707 is an orally active, nonpeptide and selective Endothelin-A receptor antagonist [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 162412-70-6. Pack Sizes: 5 mg. Product ID: HY-123744. | |
| PD166326 | PD166326 is a pyridopyrimidine-type inhibitor of receptor tyrosine kinases , with IC 50 s of 6 nM and 8 nM for Src and Abl , respectively. PD166326 exhibits antileukemic activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 185039-91-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-118144. | |
| PD-166866 | PD166866 is a selective FGFR1 tyrosine kinase inhibitor with an IC 50 of 52.4 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 192705-79-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101296. | |
| PD-168077 maleate | PD-168077 maleate is a selective dopamine D 4 receptor agonist, with a K i of 9 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 630117-19-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-21098A. | |
| PD 174265 | PD 174265 is a potent, cell-permeable, reversible, and selective inhibitor of EGFR with an IC 50 of 450 pM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 216163-53-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112411. | |
| PD-1/PD-L1-IN-23 | PD-1/PD-L1-IN-23 is a potent and orally active inhibitor of PD-1/PD-L1. PD-1/PD-L1-IN-23 is an ester proagent of L7. L7 is a benzo[c][1,2,5]oxadiazole derivative and biologically evaluated as inhibitors of PD-L1. PD-1/PD-L1-IN-23 displays significant antitumor effects in tumor models of syngeneic and PD-L1 humanized mice [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2597056-04-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145774. | |
| PDAT | PDAT is a noncompetitive indolethylamine-N-methyltransferase (INMT) inhibitor with a K i of 84 μM for rabbit lung INMT (rabINMT) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1226213-83-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124101. | |
| PDCD4-IN-1 | PDCD4-IN-1(compound 20031600) is a PDCD4 inhibitor with a K d value of 350 nM, which can promote the expression of BDNF in hippocampal neuron cell HT-22 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 494763-64-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153383. | |
| PdCl2(Amphos)2 | PdCl2(Amphos)2 is a catalyst that is more suitable for use in water than organic solvents [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 887919-35-9. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-W010686. | |
| PDDC | PDDC is a compound used to inhibit Alzheimer's disease. It is a nSMase2 inhibitor that can inhibit tau-induced nSMase2 activity and ceramide elevation, and slow the spread of tau in mouse models. Uses: Scientific research. Group: Signaling pathways. CAS No. 2232878-43-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-156800. | |
| PDE-9 inhibitor | PDE-9 inhibitor is useful for neurodegenerative diseases. Uses: Scientific research. Group: Signaling pathways. CAS No. 1082743-70-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-50865. | |
| p-Dimethylaminobenzaldehyde | p-Dimethylaminobenzaldehyde (4-Dimethylaminobenzaldehyde) can be used as a chromogenic reagent or as an absorbent agent for heavy metal ions [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 4-Dimethylaminobenzaldehyde. CAS No. 100-10-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-Y0015. | |
| PDK1 allosteric modulator 1 | PDK1 allosteric modulator 1 is a molecule targeting PDK1 with a binding affinity of 8 μM. PDK1 allosteric modulator 1 is able to bind to the PIF pocket of PDK1, potentially affecting the biological activity of this kinase [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 303134-93-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-W837864. | |
| PD-L1-IN-1 | PD-L1-IN-1 is a potent PD-L1 inhibitor with an IC 50 of 115 nM. PD-L1-IN-1 strongly binds with the PD-L1 protein and challenged it in a co-culture of PD-L1 expressing cancer cells (PC9 and HCC827 cells) and peripheral blood mononuclear cells enhanced antitumor immune activity of the latter. PD-L1-IN-1 significantly increased interferon γ release and apoptotic induction of cancer cells, with low cytotoxicity in healthy cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2767424-13-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139781. | |
| PD-L1-IN-2 | PD-L1-IN-2 is a potential tumor immunological agent by inhibiting PD-L1. PD-L1-IN-2 is a Naamidine J derivative and exerts antitumor effects in vivo by reducing PD-L1 expression and enhancing tumor-infiltrating T-cell immunity. PD-L1-IN-2 is used for colorectal cancer research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2894733-91-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-149830. | |
| PD-L1-IN-3 | PD-L1-IN-3 (Compound 4a) is a compound that targets PD-1/PD-L1, the IC 50 value and EC 50 value is 4.97nM and 2.70 μM for inhibit PD-L1 and Jurkat T cells, respectively. PD-L1-IN-3 can bind PD-L1 dimer to prevent PD-1 binding to PD-L1, therefore blocking PD-1 signaling. PD-L1-IN-3 can be used for lung cancer and melanoma diseases research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2953044-29-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-155101. | |
| PDM2 | PDM2 is a selective, high-affinity aryl hydrocarbon receptor ( AhR ) antagonist with an K i of 1.2±0.4 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 688348-25-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-112629. | |
| PDMP hydrochloride | PDMP hydrochloride is a glucosylceramide synthase (GCS) inhibitor. PDMP hydrochloride induces apoptosis in K562/A02 cells. PDMP hydrochloride can be used in cancer (such as leukemia) research [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 73257-80-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-116392D. | |
| PE 22-28 | PE 22-28 is a TREK-1 inhibitor with IC 50 value of 0.12 nM. PE 22-28 also is a 7 amino-acid peptide that is used as a core sequence for preparing analogs by chemical modifications and also by substitution of amino-acids. PE 22-28 can be used for the research of depression [1]. Uses: Scientific research. Group: Peptides. CAS No. 1801959-12-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P3581. | |
| Pectin | Pectin is a heteropolysaccharide, derived from the cell wall of higher plants. Pectin involves in the formation of nanoparticles as a delivery vehicle of agents. Pectin is also an adsorbent, a broad-spectrum antimicrobial agent that binds to bacteria toxins and other irritants in the intestinal mucosa, relieves irritated mucosa [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 9000-69-5. Pack Sizes: 100 mg; 1 g; 5 g. Product ID: HY-W145518. | |
| Pectinase, aspergillus niger | Pectinase (EC 3.2.1.15) is a mixed enzymes that hydrolyze pectic substances, it mostly presents in microorganisms and higher plants. Pectinase is involved in the metabolism of the cell wall as well as in the growth of the cell, senescence, ripening of fruits, pathogenesis and abscission process [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EC 3.2.1.15. CAS No. 9032-75-1. Pack Sizes: 5 g; 10 g; 50 g. Product ID: HY-126386. | |
| Pectolinarigenin | Pectolinarigenin is a dual inhibitor of COX-2 / 5-LOX. Anti-inflammatory activity [1]. Pectolinarigenin has potent inhibitory activities on melanogenesis [2]. Uses: Scientific research. Group: Natural products. CAS No. 520-12-7. Pack Sizes: 5 mg; 10 mg; 20 mg. Product ID: HY-N0493. | |
| Peficitinib | Peficitinib (ASP015K) is an orally active JAK inhibitor, with IC 50 s of 3.9, 5.0, 0.7 and 4.8 nM for JAK1, JAK2, JAK3 and Tyk2, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ASP015K; JNJ-54781532. CAS No. 944118-01-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-19568. | |
| Pefloxacin | Pefloxacin is a an antibacterial agent and prevents bacterial DNA replication by inhibiting DNA gyrase (topoisomerse) Target: DNA gyrase Pefloxacin is a synthetic chemotherapeutic agent used to treat severe and life-threatening bacterial infections. Uses: Scientific research. Group: Natural products. Alternative Names: Pefloxacinium. CAS No. 70458-92-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-B0147. | |
| Pefloxacin mesylate | Pefloxacin mesylate is a an antibacterial agent and prevents bacterial DNA replication by inhibiting DNA gyrase (topoisomerse) Target: DNA gyrase Pefloxacin is a synthetic chemotherapeutic agent used to treat severe and life-threatening bacterial infections. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Pefloxacinium mesylate. CAS No. 70458-95-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0147A. | |
| PEG10000 | PEG10000 (Polyethylene glycol 10000) can be used as a solubilizer. PEG10000 is a kind of biological materials or organic compounds that are widely used in life science research [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Polyethylene glycol 10000. CAS No. 25322-68-3. Pack Sizes: 25 g; 50 g; 100 g. Product ID: HY-Y0873P. | |
| PEG200 | PEG200 (Polyethylene glycol 200), a neutral polymer of molecular weight 200, is a water-soluble, low immunogenic and biocompatible polymer formed by repeating units of ethylene glycol [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Polyethylene glycol 200. CAS No. 25322-68-3. Pack Sizes: 25 g; 50 g; 100 g; 500 g. Product ID: HY-Y0873K. | |
| PEG2000 | PEG2000 (Polyethylene glycol 2000) is a solvent for a large number of substances. PEG2000 can be used as a carrier material and modifying agent. PEG2000 is widely used in a variety of pharmaceutical formulations [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Polyethylene glycol 2000. CAS No. 25322-68-3. Pack Sizes: 10 g; 25 g; 50 g; 100 g. Product ID: HY-Y0873B. | |
| PEG20000 | PEG20000 (Polyethylene glycol 20000) can be used as a solubilizer. PEG20000 is a kind of biological materials or organic compounds that are widely used in life science research, can be degraded by bacteria [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Polyethylene glycol 20000. CAS No. 25322-68-3. Pack Sizes: 100 g; 250 g; 500 g; 1 k g. Product ID: HY-Y0873Q. | |
| PEG3 | PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 67439-82-1. Pack Sizes: 100 mg; 250 mg. Product ID: HY-W096121. | |
| PEG3350 | PEG3350 (Polyethylene glycol 3350) a neutral polymer of molecular weight 3350. PEG3350 used as an excellent solvent for a large number of substances. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Polyethylene glycol 3350. CAS No. 25322-68-3. Pack Sizes: 25 g; 50 g; 100 g; 500 g. Product ID: HY-Y0873C. | |
| PEG35000 | PEG35000 is a polyethylene glycol with a molecular weight of 35,000 that can be used as a carrier material and modifier in drug delivery systems [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Polyethylene glycol 35000. CAS No. 25322-68-3. Pack Sizes: 100 mg; 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-Y0873O. | |
| PEG400 | PEG400 is a strongly hydrophilic polyethylene glycol used as an excellent solvent for a large number of substances. PEG400 is widely used in a variety of pharmaceutical formulations. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Polyethylene glycol 400. CAS No. 25322-68-3. Pack Sizes: 50 mL; 100 mL. Product ID: HY-Y0873A. | |
| PEG4-SPDP | PEG4-SPDP is a cleavable ADC linker used for the antibody-drug conjugates (ADCs). Uses: Scientific research. Group: Signaling pathways. CAS No. 1305053-43-3. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-126496. | |
| PEG8000 | PEG8000 can be used for phage precipitation, isolation of plasmid DNA, and promotion of flat end-junction reactions [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Polyethylene glycol 8000. CAS No. 25322-68-3. Pack Sizes: 10 g; 25 g; 50 g; 100 g; 500 g. Product ID: HY-Y0873J. | |
| Peiminine | Peiminine is a compound that can be isolated from Bolbostemma paniculatum (Maxim) Franquet (Cucurbitaceae family). Peiminine can induce apoptosis in human hepatocellular carcinoma HepG2 cells through both extrinsic and intrinsic apoptotic pathways. Peiminine has anti-inflammatory, anticancer, anti-osteoporosis, cardioprotective and other activities in many animal models [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Natural products. Alternative Names: Verticinone; Raddeanine. CAS No. 18059-10-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N0213. | |
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