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Mal-PEG2-Val-Cit-PAB-OH
Mal-PEG2-Val-Cit-PAB-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Mal-PEG2-Val-Cit-PAB-OH also can be used as a PROTAC linker that can be used in the synthesis of PROTACs. Uses: Scientific research. Group: Signaling pathways. CAS No. 2055041-38-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-130222.
Mal-PEG3-NH2 TFA
Mal-PEG3-NH2 TFA is a linear heterobifunctional PEG crosslinker with Maleimide (HY-W007324) and amine. Mal-PEG3-NH2 TFA is a non-degradable (non-cleavable) PROTAC linker[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2830214-77-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-W190796A.
Mal-?PEG4-?NHS ester
Mal-PEG4-NHS ester is a non-cleavable ADC linker which links Quantum dots (QDs) with PEGylated liposomes [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1325208-25-0. Pack Sizes: 50 mg; 100 mg; 250 mg. Product ID: HY-126505.
Mal-PEG4-VA-PBD
Mal-PEG4-VA-PBD is a agent-linker conjugate for ADC by using the antitumor antibiotic, Pyrrolobenzodiazepine (PBD), linked via Mal-PEG4-VA. Uses: Scientific research. Group: Signaling pathways. CAS No. 1342820-68-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-126685.
Mal-PEG4-VC-PAB-DMEA-PNU-159682
Mal-PEG4-VC-PAB-DMEA-PNU-159682, a agent-linker conjugate for ADC, consists the ADC linker Mal-PEG4-VC-PAB and a potent ADC cytotoxin DMEA-PNU-159682. DMEA-PNU-159682 includes metabolites of nemorubicin (MMDX) from liver microsomes and ADC cytotoxin PNU-159682[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2259318-52-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-126687.
Mal-PEG8-acid
Mal-PEG8-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Uses: Scientific research. Group: Signaling pathways. CAS No. 1818294-46-0. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-130334.
Mal-PEG8-NHS ester
Mal-PEG8-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Uses: Scientific research. Group: Signaling pathways. CAS No. 2055033-05-9. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg; 1 g. Product ID: HY-126887.
Mal-PEG8-Val-Ala-PAB-Exatecan
Mal-PEG8-Val-Ala-PAB-Exatecan (Compound 9b) is an antibody-drug conjugate linker (ADC linker) that binds to Nectin-4 polypeptides conjugated to chemotherapeutic agents. Mal-PEG8-Val-Ala-PAB-Exatecan can be used for cancer research[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2679821-39-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147271.
Mal-PEG8-Val-Cit-PAB-MMAE
Mal-PEG8-Val-Cit-PAB-MMAE is a agent-linker conjugate for ADC. Mal-PEG8-Val-Cit-PAB-MMAE contains a cleavable ADC linker and a potent tubulin inhibitor MMAE (HY-15162)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2353409-69-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-141156.
MALT1 inhibitor MI-2
MALT1 inhibitor MI-2 is a MALT1 inhibitor (IC50=5.84 ?M). MALT1 inhibitor MI-2 binds directly to MALT1, irreversibly suppresses protease function and is accompanied by NF-?B reporter activity suppression, c-REL nuclear localization inhibition, and NF-?B target gene downregulation. MALT1 inhibitor MI-2 shows nontoxic to animals[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1047953-91-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12276.
Maltitol (Standard)
Maltitol (Standard) is the analytical standard of Maltitol. This product is intended for research and analytical applications. Maltitol is a sugar alcohol used as a sugar substitute. It has 75-90% of the sweetness of sucrose (table sugar) and nearly identical properties. Maltitol may also be used as a plasticizer in gelatin capsules, as an emollient, and as a humectant [1]. Uses: Scientific research. Group: Natural products. CAS No. 585-88-6. Pack Sizes: 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-B2122R.
Maltobionic acid
Maltobionic acid is a naturally-derived polyhydroxy bionic acid. Maltobionic acid shows iron chelating ability, antibacterial potential and cytoprotection [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: 4-O-α-D-Glucopyranosyl-D-gluconic acid. CAS No. 534-42-9. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-W423191.
Maltoheptaose
Maltoheptaose is an activator of phosphorylase B to prepare heptulose-2-phosphate. Maltoheptaose is a maltooligosaccharide contanins seven glucose units [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 34620-78-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-127018.
Maltohexaose
Maltohexaose is a natural saccharide, and can be produced from amylose, amylopectin and whole starch. Uses: Scientific research. Group: Natural products. Alternative Names: Amylohexaose. CAS No. 34620-77-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N2559.
Maltol
Maltol, a type of aromatic compound, is an antioxidant agent. Maltol enhances neural function by mitigating oxidative stress and cell apoptosis. Maltol is an inhibitor of oxidative damage in nerve cells and is effective in preventing diabetic peripheral neuropathy (DPN). Maltol is used extensively as a safe flavoring agent and food preservative. Maltol is a metal ion chelator that can be used in the field of catalysis, cosmetics, and medicine [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 118-71-8. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-W012788.
Maltononaose
Maltononaose is a linear oligosaccharide consisting of 9 glucose units linked by alpha-1, 4-glucoside bonds. Maltononaose is used as a substrate to study the subsites affinity of glucoamylase. Maltononaose can be used to determine the activity of amylase and to optimize the process of starch hydrolysis [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 6471-60-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N8326.
Maltooctaose
Maltooctaose, a specific-length maltooligosaccharide, can be produced by PFTA ( Pyrococcus furiosus ) [1]. Uses: Scientific research. Group: Natural products. CAS No. 66567-45-1. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-N9406.
Maltopentaose
Maltopentaose is the shortest chain oligosaccharide. Maltopentaose is a substrate for ?-amylases. Maltopentaose can be classified as maltodextrin and is also used in a study to investigate glycation and phosphorylation of ?-lactalbumin. Maltopentaose is used to study the inhibition kinetics of human pancreatic ?-amylase by dehydrodieugenol B[1][2][3]. Uses: Scientific research. Group: Natural products. Alternative Names: Maltopentose. CAS No. 34620-76-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-N1495.
Maltose
Maltose is a disaccharide formed from two units of glucose joined with an α(1→4) bond, a reducing sugar. Maltose monohydrate can be used as a energy source for bacteria. Uses: Scientific research. Group: Natural products. CAS No. 69-79-4. Pack Sizes: 500 mg; 1 g; 5 g. Product ID: HY-N2024.
Maltose monohydrate
Maltose monohydrate is the energy source for bacteria. Uses: Scientific research. Group: Natural products. CAS No. 6363-53-7. Pack Sizes: 10 mM * 1 mL; 10 g; 25 g. Product ID: HY-N2024A.
Maltose monohydrate (Standard)
Maltose monohydrate (Standard) is the analytical standard of Maltose monohydrate. This product is intended for research and analytical applications. Maltose monohydrate is the energy source for bacteria. Uses: Scientific research. Group: Natural products. CAS No. 6363-53-7. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-N2024AR.
Maltose phosphorylase
Maltose phosphorylase is a dimerase which catalyzes the transformation of maltose and inorganic phosphate into β-D-glucose-1-phosphate and glucose. Maltose phosphorylases have been classified in family 65 of the glycoside hydrolases [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: E.C. 2.4.1.8. CAS No. 9030-19-7. Pack Sizes: 50 U; 250 U. Product ID: HY-P2741.
Maltotetraose
Maltotetraose can serve as a substrate for enzyme-linked assays to measure amylase activity in biological fluids. Maltotetraose has oral active, and reduces TNF-α -induced inflammatory responses by inhibiting NF-κB activity and decreasing ICAM-1 expression. Maltotetraose also inhibits PDGF -induced vascular smooth muscle cell migration and neovascularization. Additionally, Maltotetraose derivatives can function as probes for detecting bacterial infections by targeting the maltodextrin transporter. With good long-term safety, Maltotetraose holds promise for research in atherosclerosis-related diseases [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Amylotetraose; Fujioligo 450; α-1,4-Tetraglucose. CAS No. 34612-38-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N2464.
Maltotriose
Maltotriose, the second most abundant sugar present in brewing, is an inducer of the maltose regulon of Escherichia coli. Maltotriose can induce beta-galactosidase synthesis [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 1109-28-0. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-113011.
Maltulose monohydrate
Maltulose monohydrate (4-O-α-D-Glucopyranosyl-D-fructose monohydrate) can be used as an energy source for bacteria. Maltulose monohydrate is a biomaterial or organic compound that can be used in life science research [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: 4-O-α-D-Glucopyranosyl-D-fructose monohydrate. CAS No. 207511-09-9. Pack Sizes: 50 mg; 100 mg. Product ID: HY-W415909.
Mal-Val-Ala-PAB-N(SO2Me)-Exatecan
Mal-Val-Ala-PAB-N(SO2Me)-Exatecan (Compound LE14) is a conjugate of an ADC toxin Exatecan (HY-13631) and a linker Mal-Val-Ala-PAB-N(SO2Me). Mal-Val-Ala-PAB-N(SO2Me)-Exatecan can be used for synthesis of ADC FZ-AD005. FZ-AD005 is a delta-like ligand 3 (DLL3, KD=58.3 pM) targeting ADC, that exhibits antitumor efficacy against SCLC cancer[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2575682-08-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-159072.
Mal-VC-PAB-DM1
Mal-VC-PAB-DM1 is a agent-linker conjugate for ADC with potent antitumor activity by using DM1 (a potent microtubule-disrupting agent), linked via the ADC linker Mal-VC-PAB [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1464051-44-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126682.
Malvidin-3-galactoside chloride
Malvidin-3-galactoside chloride, an anthocyanin monomer, induces hepatocellular carcinoma (HCC) cells cycle arrest and apoptosis. Malvidin-3-galactoside chloride inhibits the production and accumulation of ROS. Malvidin-3-galactoside chloride has anti-tumor function [1]. Uses: Scientific research. Group: Natural products. CAS No. 30113-37-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N6623.
Malvidin-3-glucoside chloride
Malvidin-3-glucoside chloride (Malvidin-3-O-glucoside chloride), a major wine anthocyanin, is effective in promoting resilience against stress by modulating brain synaptic plasticity and peripheral inflammation [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Malvidin-3-O-glucoside chloride; Oenin chloride. CAS No. 7228-78-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-125740.
Malvidin chloride
Malvidin (chloride) is a bioactive compound isolated from grape. Malvidin shows cytotoxicity through the arrest of the G 2 /M phase of cell cycle and induction of apoptosis. Malvidin can be used for the research of cancer [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Syringidin. CAS No. 643-84-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-122496.
Mancozeb
Mancozeb is a widely used fungicide that is effective against fungal diseases in most cereals, vegetables, fruits and ornamental plants. In addition, Mancozeb can cause liver damage in mice by activating the Keap1/Nrf2 signaling pathway. Mancozeb upregulates lactate dehydrogenase and cytochrome c to alter cell metabolism and induce cell death. Mancozeb has reproductive toxicity and can induce apoptosis in ovarian cells [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 8018-1-7. Pack Sizes: 500 mg; 1 g. Product ID: HY-B0854.
Mandelic acid
Mandelic acid ((±)-Mandelic acid), an alpha-hydroxycarboxylic acid, has been widely used as an intermediate of pharmaceutical and fine chemicals. Mandelic acid shows antimicrobial activity and has been used for the research of urinary tract infections and vaginal trichomoniasis. Mandelic acid exhibits high sperm-immobilizing activity and low vaginal irritation [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: (±)-Mandelic acid; DL-Mandelic acid. CAS No. 90-64-2. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-W015591.
Mandipropamid
Mandipropamid displays outstanding activity against late blight diseases of potato and tomato, combined with excellent efficacy on downy mildew diseases of grape and cucumber [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 374726-62-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-W744966.
Mangafodipir trisodium
Mangafodipir trisodium (MnDPDP), hepatocellular-specific contrast agent, is an efficacious inhibitor of CIPN (chemotherapy-induced peripheral neuropath) and other conditions caused by cellular oxidative stress. Mangafodipir trisodium shows no negative interference with the tumoricidal activity of chemotherapy [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MnDPDP. CAS No. 140678-14-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0993.
Manganese chloride
Manganese chloride is a new oral active magnetic resonance liver contrast agent for patients with renal impairment [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Manganese dichloride. CAS No. 7773-1-5. Pack Sizes: 100 g; 500 g. Product ID: HY-W019894.
Mangiferin
Mangiferin is a Nrf2 activator. Mangiferin suppresses nuclear translocation of the NF-κB subunits p65 and p50. Mangiferin exhibits antioxidant, antidiabetic, antihyperuricemic, antiviral, anticancer and antiinflammatory activities [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 4773-96-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0290.
Mangiferin (Standard)
Mangiferin (Standard) is the analytical standard of Mangiferin. This product is intended for research and analytical applications. Mangiferin is a Nrf2 activator. Mangiferin suppresses nuclear translocation of the NF-κB subunits p65 and p50. Mangiferin exhibits antioxidant, antidiabetic, antihyperuricemic, antiviral, anticancer and antiinflammatory activities [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 4773-96-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0290R.
Manidipine
Manidipine is a calcium channel blocker that is used clinically as an antihypertensive. Uses: Scientific research. Group: Signaling pathways. CAS No. 89226-50-6. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B0419.
Manidipine dihydrochloride
Manidipine dihydrochloride is a third-generation, lipophilic, orally active and highly vasoselective calcium channel antagonist ( IC 50 = 2.6 nM in guinea-pig ventricular cells) and acts as an antihypertensive agent. Manidipine effectively reduces blood pressure as well as improving insulin sensitivity, renal protection, and antiatherosclerotic activity. Manidipine also exerts anti-inflammatory activity mediated by NF-κB and antiviral activity against many flavivirus and negative-strand RNA viruses through the inhibition of calcium channel. Manidipine is widely applied to research of cardiovascular, metabolic disease and infection [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CV-4093. CAS No. 89226-75-5. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-17403.
m-Anisaldehyde
m-Anisaldehyde is an endogenous metabolite. Uses: Scientific research. Group: Natural products. Alternative Names: 3-Methoxybenzaldehyde. CAS No. 591-31-1. Pack Sizes: 10 mM * 1 mL; 10 g; 25 g. Product ID: HY-W007346.
Mannan
Mannan is an orally active polysaccharide compound that binds to the mannose receptor (MR). Mannan promotes bacterial uptake and endosomal degradation by binding to MR, thereby enhancing the production of IL-12 in immune cells. Mannan enhances ROS production. Mannan modulates immunity, inhibits Aflatoxin B 1 (HY-N6615)-induced toxicity, and reduces lipid [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 9036-88-8. Pack Sizes: 50 mg; 100 mg. Product ID: HY-W145667.
Manogepix
Manogepix (E1210) is a first-in-class, broad-spectrum and orally active antifungal. Manogepix has a mechanism of action-inhibition of fungal glycosylphosphatidylinositol (GPI) biosynthesis [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: E1210; APX001A. CAS No. 936339-60-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18233.
MANS peptide
MANS peptide is an inhibitor for myristoylated alanine-rich C kinase substrate ( MARCKS ), which competes with MARCKS in cells for membrane binding, and thus inhibits the stimulation of mucin secretion and tumor metastasis [1]. Uses: Scientific research. Group: Peptides. CAS No. 479482-23-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P10218.
Manumycin A
Manumycin A is a polyketide antibiotic and an inhibitor of thioredoxin reductase 1 (TrxR-1). Manumycin A can inhibit the growth of breast cancer cells and exert its anti-tumor activity through LC3. Manumycin A can downregulate the release of pro-inflammatory cytokines in human monocytes stimulated by TNF ?, and has potential anti-inflammatory activity. Manumycin A can inhibit the Ras/Raf/ERK1/2 signaling and hnRNP H1 in castration resistant prostate cancer cells to suppress exosome biogenesis and secretion[1][3][4].. Uses: Scientific research. Group: Natural products. CAS No. 52665-74-4. Pack Sizes: 1 mg. Product ID: HY-N6796.
Manzamine A
Manzamine A, an orally active beta-carboline alkaloid, inhibits specifically GSK-3β and CDK-5 with IC 50 s of 10.2 μM and 1.5 μM, respectively. Manzamine A targets vacuolar ATPases and inhibits autophagy in pancreatic cancer cells. Manzamine A has antimalarial and anticancer activities. Manzamine A also shows potent activity against HSV-1 [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Keramamine A. CAS No. 104196-68-1. Pack Sizes: 1 mg. Product ID: HY-117025.
Manzamine A hydrochloride
Manzamine A hydrochloride, an orally active beta-carboline alkaloid, inhibits specifically GSK-3β and CDK-5 with IC 50 s of 10.2 μM and 1.5 μM, respectively. Manzamine A hydrochloride targets vacuolar ATPases and inhibits autophagy in pancreatic cancer cells. Manzamine A hydrochloride has antimalarial and anticancer activities. Manzamine A hydrochloride also shows potent activity against HSV-1 [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Keramamine A hydrochloride. CAS No. 104264-80-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-117025A.
MAO-A inhibitor 1
MAO-A inhibitor 1 (compound VIII) is a MAO-A inhibitor, with an IC 50 of 100 μM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 119229-96-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N12485.
MAOS
MAOS is a modified Trinders reagent that can be used as a chromogenic probe for the determination of H 2 O 2. MAOS is strongly dependent on the pH of the reaction medium [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 82692-97-5. Pack Sizes: 100 mg; 250 mg. Product ID: HY-15923.
MAP4343
MAP4343 is the 3-methylether derivative of Pregnenolone. MAP4343 binds in vitro to microtubule-associated protein 2 (MAP2), stimulates the polymerization of tubulin, enhances the extension of neurites and protects neurons against neurotoxic agents [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 511-26-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107116.
MAP855
MAP855 is a highly potent, selective, ATP-competitive and orally active MEK1/2 kinase inhibitor (MEK1 ERK2 cascade IC50=3 nM, pERK EC50=5 nM). MAP855 shows equipotent inhibition of wild-type and mutant MEK1/2[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1660107-77-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145702.
Mapatumumab
Mapatumumab (HGS-ETR1) is a fully human IgG1 agonistic monoclonal antibody that targets tumor necrosis factor-related apoptosis-inducing ligand receptor 1 ( TRAIL-R1 ). Mapatumumab can be used for the research of cancer [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: HGS-ETR1; Anti-Human TNFRSF10A Recombinant Antibody. CAS No. 658052-09-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99265.
Mapenterol hydrochloride
Mapenterol hydrochloride is a type of β2-adrenoceptor agonist [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 54238-51-6. Pack Sizes: 5 mg. Product ID: HY-136435.
Mapracorat
Mapracorat is a novel non-steroidal selective glucocorticoid receptor agonist. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ZK-245186; BOL-303242X. CAS No. 887375-26-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-14864.
Maprotiline hydrochloride is a highly selective noradrenergic reuptake inhibitor that has strong antidepressant, antitumor and neuropathic pain-relieving effects with oral activity. Maprotiline hydrochloride induces cancer cell apoptosis by targeting the ERK signaling pathway and CRABP1 [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 10347-81-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0444.
Maralixibat chloride
Maralixibat (SHP625) chloride is an orally active ileal bile acid transporter (IBAT) inhibitor. Maralixibat chloride can be used for the research of rare cholestatic liver diseases including Alagille syndrome (ALGS), progressive familial intrahepatic cholestasis (PFIC) and biliary atresia [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SHP625 chloride; LUM001 chloride; Lopixibat chloride. CAS No. 228113-66-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16747.
Maraviroc
Maraviroc (UK-427857) is a selective CCR5 antagonist with activity against human HIV. Uses: Scientific research. Group: Signaling pathways. Alternative Names: UK-427857. CAS No. 376348-65-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13004.
Marbofloxacin
Marbofloxacin is a third generation fluoroquinolone and orally active antimicrobial agent, which has a broad spectrum bactericidal activity and good efficacy. Marbofloxacin can be used for the research of infections by Gram-positive and Gram-negative bacteria and Mycoplasma [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 115550-35-1. Pack Sizes: 100 mg; 500 mg. Product ID: HY-B0126.
Mardepodect
Mardepodect (PF-2545920) is a potent, orally active and selective PDE10A inhibitor with an IC 50 of 0.37 nM, with >1000-fold selectivity over other PDEs. Mardepodect can cross the blood-brain barrier [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PF-2545920. CAS No. 898562-94-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-50098.
Mardepodect hydrochloride
Mardepodect hydrochloride (PF-2545920 hydrochloride) is a potent, orally active and selective PDE10A inhibitor with an IC 50 of 0.37 nM, with >1000-fold selectivity over other PDEs. Mardepodect hydrochloride can cross the blood-brain barrier [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PF-2545920 hydrochloride. CAS No. 2070014-78-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-50098A.
Maresin 1
Maresin 1, produced by human Mφs from endogenous docosahexaenoic acid (DHA) and a specialized proresolving mediator, stimulates intracellular [Ca 2+ ] and secretion. Maresin 1 possesses anti-inflammatory activity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1268720-28-0. Pack Sizes: 10 μg (277.4 μM * 100 μL in Ethanol); 25 μg (277.4 μM * 250 μL in Ethanol). Product ID: HY-116429.
Margetuximab
Margetuximab (MGAH22) is a chimeric anti- HER2 monoclonal antibody optimized Fc domain, with an EC 50 value of 39.33 ng/mL. Margetuximab can be used for researching metastatic HER2-positive breast cancer [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1350624-75-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99030.
Maribavir
Maribavir is a potent inhibitor of histone phosphorylation catalyzed by wild-type pUL97 in vitro, with an IC 50 of 3 nM. Maribavir has potent antiviral activity against HCMV and Epstein-Barr virus ( EBV ). Uses: Scientific research. Group: Signaling pathways. Alternative Names: 1263W94; BW1263W94; GW257406X. CAS No. 176161-24-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16305.
Maridebart
Maridebart is a human immunoglobulin G1-kappa, anti-GIPR (gastric inhibitory polypeptide receptor) monoclonal antibody [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: AMG133 antibody. CAS No. 2761478-99-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990047.
Maridebart cafraglutide
Maridebart cafraglutide (AMG 133) is an antibody-peptide conjugate acting as a GLP-1 receptor agonist and an antagonist of the GIP receptor. Maridebart cafraglutide reduces body weight and improve metabolic markers in male obese mice and cynomolgus monkeys. Maridebart cafraglutide is promising for research of obesity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AMG 133. CAS No. 2887445-76-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-164535.
Marimastat
Marimastat (BB2516) is a broad spectrum and orally bioavailable inhibitor of MMPs , with potent activity against MMP-9 ( IC 50 =3 nM), MMP-1 ( IC 50 =5 nM), MMP-2 ( IC 50 =6 nM), MMP-14 ( IC 50 =9 nM) and MMP-7 ( IC 50 =13 nM), used in the treatment of cancer. Marimastat (BB2516) is an angiogenesis and metastasis inhibitor, which limits the growth and production of blood vessels. As an antimetatstatic agent it prevents malignant cells from breaching the basement membranes [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BB2516; TA2516. CAS No. 154039-60-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-12169.
Marizomib
Marizomib (Salinosporamide A) is a second-generation, irreversible, brain-penetrant, pan-proteasome inhibitor. Marizomib inhibits the CT-L (β5), CT-T-laspase-like (C-L, β1) and trypsin-like (T-L, β2) activities of the 20S proteasome (IC 50 =3.5, 28, and 430 nM, respectively) [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Salinosporamide A; NPI-0052. CAS No. 437742-34-2. Pack Sizes: 100 μg; 500 μg; 1 mg; 5 mg. Product ID: HY-10985.
MARK4 inhibitor 1
MARK4 inhibitor 1 is a potent and selective microtubule affinity-regulating kinase 4 (MARK4) inhibitor, with an IC50 of 1.54 ?M. MARK4 inhibitor 1 inhibits cancer cell proliferation, metastasis and induces apoptosis[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2271081-58-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114317.
MARK-IN-1
MARK-IN-1 is a potent microtubule affinity regulating kinase ( MARK ) inhibitor with an IC 50 of <0.25 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1109283-93-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-101933.
MARK-IN-2
MARK-IN-2 is a potent microtubule affinity regulating kinase ( MARK ) inhibitor with an IC 50 of 5 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1314893-26-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101934.