MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Luciferase, firefly | Luciferase, firefly is the light-emitting enzyme responsible for the bioluminescence of fireflies and click beetles. Uses: Scientific research. Group: Peptides. CAS No. 61970-00-1. Pack Sizes: 1 mg. Product ID: HY-P1004A. |  |
| Luciferase-IN-4 | Luciferase-IN-4 (Compound 6b) is an inhibitor for luciferase with IC 50 of 4.1 μM. Luciferase-IN-4 inhibits purified luciferase in P. pyralis with IC 50 of 2.0 μM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1020413-85-7. Pack Sizes: 1 mg. Product ID: HY-161475. | |
| Lucifer Yellow CH dipotassium salt | Lucifer Yellow CH dipotassium is a high-intensity fluorescent probe containing free hydrazyl groups. Lucifer Yellow CH can react with fatty aldehydes at room temperature. Lucifer Yellow CH serves as a biological tracer to monitor neuronal branching, regeneration, gap junction detection and characterization, and selective ablation of cells after aldehyde fixation. Lucifer yellow CH displays the maximum excitation/emission of 430 nm/540 nm, respectively [1] [2]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 71206-95-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-W127715. | |
| Lucigenin | Lucigenin is a chemiluminescence probe. Lucigenin can be used to detect the production of endogenous superoxide anion radical (O 2- ). Lucigenin is extremely sensitive to chloride ions, while it combined with chloride ions, the fluorescence will be quenched. Lucigenin also can be used as a chloride indicator. Ex/Em=455/505 nm [1]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: NSC-151912; L-6868. CAS No. 2315-97-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-D0720. | |
| Lucitanib | Lucitanib (E-3810) is a novel dual inhibitor of VEGFR and FGFR , potently and selectively inhibits VEGFR1 , VEGFR2 , VEGFR3 , FGFR1 and FGFR2 with IC 50 s of 7 nM, 25 nM, 10 nM, 17.5 nM, and 82.5 nM, respectively [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: E-3810. CAS No. 1058137-23-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15391. | |
| lucPpy-IN-1 | lucPpy-IN-1 (compound 9) is an ATP-dependent luciferase from Photinus pyralis ( lucPpy ) inhibitor with an IC 50 value of 4.0 μM. lucPpy-IN-1 can be used for the research of targets agentgability [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 546100-66-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148407. | |
| LUF5834 | LUF5834 is a selective A 2B adenosine receptor ( A2BR ) partial agonist ( EC 50 = 12 nM). LUF5834 is also a partial A 1 /A 2A adenosine receptor agonist (lacking selectivity) with K i values of 2.6 and 28 nM, respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 333962-91-7. Pack Sizes: 5 mg. Product ID: HY-103170. | |
| Lufenuron | Lufenuron is an orally active lipophilic benzoylurea insecticide and a chitin synthesis inhibitor that can used for flea and fish lice control. Lufenuron inhibits moulting of arthropods. Lufenuron induces reproductive toxicity, genotoxic effects and oxidative stresses in pregnant albino rats and their fetuses [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 103055-07-8. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-115584. | |
| Lugdunin | Lugdunin is an antibiotic peptide. Lugdunin inhibits bacteria by dissipating their membrane potential. Lugdunin is active against Gram-positive bacteria, such as S. aureus , and reduces S. aureus skin and nasal colonization. Lugdunin induces LL-37 and CXCL8/MIP-2 in human keratinocytes and mouse skin [1]. Uses: Scientific research. Group: Peptides. CAS No. 1989698-37-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P4200. | |
| Luliconazole | Luliconazole (NND 502) is a topical antifungal imidazole antibiotic with broad-spectrum and potent antifungal activity. Luliconazole can be used for the research of skin infection, including dermatophytosis, tinea corporis, tinea pedis et al [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NND 502. CAS No. 187164-19-8. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 250 mg. Product ID: HY-14283. | |
| Lulizumab | Lulizumab (Humanized Anti-CD28 Recombinant Antibody) is a selective CD28 blockade, Lulizumab prevents T cell activation by selectively targeting CD28 signaling [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Humanized Anti-CD28 Recombinant Antibody. CAS No. 2235419-62-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99302. | |
| Lumacaftor | Lumacaftor (VX-809; VRT 826809) is a CFTR modulator that corrects the folding and trafficking of CFTR protein. Uses: Scientific research. Group: Signaling pathways. Alternative Names: VX-809; VRT 826809. CAS No. 936727-05-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13262. | |
| Lumasiran | Lumasiran (ALN-G01), a siRNA product, reduces hepatic oxalate production by targeting glycolate oxidase. By silencing the gene encoding glycolate oxidase, Lumasiran depletes glycolate oxidase and thereby inhibits the synthesis of oxalate, which is the toxic metabolite that is directly associated with the clinical manifestations of Primary hyperoxaluria type 1 (PH1)[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ALN-G01. CAS No. 1834610-13-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-132588. | |
| Lumasiran sodium | Lumasiran sodium, an investigational RNA interference (RNAi) therapeutic agent, reduces hepatic oxalate production by targeting glycolate oxidase. Lumasiran sodium reduces urinary oxalate excretion, the cause of progressive kidney failure in primary hyperoxaluria type 1 (PH1) [1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1834612-06-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-132613. | |
| Lumateperone | Lumateperone (ITI-007) is an orally active 5-HT2A receptor antagonist (Ki = 0.54 nM), a partial agonist of presynaptic D2 receptors and an antagonist of postsynaptic D2 receptors (Ki = 32 nM), and a dopamine D1 receptor modulator. Lumateperone has anticancer activity and can also be used for the study of schizophrenia and bipolar depression [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ITI-007. CAS No. 313368-91-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17637. | |
| Lumateperone tosylate | Lumateperone (ITI-007) tosylate is a 5-HT2A receptor antagonist (Ki = 0.54 nM), a partial agonist of presynaptic D2 receptors and an antagonist of postsynaptic D2 receptors (Ki = 32 nM), and a dopamine D1 receptor modulator. Lumateperone tosylate has anticancer activity and can also be used in studies of psychiatric disorders such as schizophrenia [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ITI-007 tosylate. CAS No. 1187020-80-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19733. | |
| Lumbokinase | Lumbokinase attenuates myocardial ischemia-reperfusion (I-R) injury through the activation of Sirt1 signaling, and thus enhances autophagic flux and reduces I-R-induced oxidative damage, inflammation and apoptosis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 556743-18-1. Pack Sizes: 1 g; 5 g; 10 g. Product ID: HY-E70008. | |
| Lumefantrine | Lumefantrine is an active antimalarial molecule used in combination with Artemether as a first- and second-line antimalarial drug with oral activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Benflumetol. CAS No. 82186-77-4. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-B0803. | |
| Lumichrome | Lumichrome, a photodegradation product of Riboflavin, is an endogenous compound in humans. Lumichrome inhibits human lung cancer cell growth and induces apoptosis via a p53-dependent mechanism. Lumichrom is the inhibitor for AKT/β-catenin signaling pathway [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 1086-80-2. Pack Sizes: 50 mg; 100 mg. Product ID: HY-115385. | |
| Lumiliximab | Lumiliximab (Anti-CD23 Recombinant Antibody) is an anti- CD23 monoclonal antibody that inhibits allergen-induced responses [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Gomiliximab; IDEC-152; ST-152. CAS No. 357613-86-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99303. | |
| Luminespib | Luminespib (VER-52296) is a potent HSP90 inhibitor with IC50s of 7.8 and 21 nM for HSP90? and HSP90?, respectively[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: VER-52296; AUY922; NVP-AUY922. CAS No. 747412-49-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-10215. | |
| Luminol | Luminol is a chemical that exhibits chemiluminescence with pK a values of 6.74 and 15.1. Luminol exhibits chemiluminescence (CL) at 425 nm λ max. Luminol is commonly used in forensics as a diagnostic tool for the detection of blood stains [1]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Diogenes reagent. CAS No. 521-31-3. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-15922. | |
| Lumiracoxib | Lumiracoxib is a potent,selective and orally active COX-2 inhibitor with a K i value of 0.06 μM [1]. Lumiracoxib acts as a nonselective NSAID with anti-inflammatory, analgesic and antipyretic activities. Lumiracoxib can be used for osteoarthritis and bone cancer research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: COX-189. CAS No. 220991-20-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-13507. | |
| Lumisterol | Lumisterol (9β,10α-Ergosterol), a steroid compound, is the (9β,10α)-stereoisomer of Ergosterol (HY-N0181). Lumisterol is a photoprotective agent against UVB-induced DNA damage and anti-proliferative activities [1]. Uses: Scientific research. Group: Natural products. Alternative Names: 9β,10α-Ergosterol. CAS No. 474-69-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0181A. | |
| Lumretuzumab | Lumretuzumab (Anti-Human ERBB3 Recombinant Antibody) is a humanized anti- HER3 (ERBB3) monoclonal antibody that can be used for the research of cancer [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-Human ERBB3 Recombinant Antibody. CAS No. 1448327-63-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99304. | |
| Lumrotatug | Lumrotatug is an anti- CD38 human IgG1 κ monoclonal antibody [1]. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001). Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2760318-99-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990747. | |
| LUNA18 | LUNA18 is an orally-available cyclic peptide KRAS and ERK inhibitor. LUNA18 phosphorylates ERK and AKT and decreases cell proliferation in RAS-mutated cancer cells. LUNA18 exhibits RAS signal inhibition and potent anti-cancer activities through inhibiting interaction between RAS and guanine nucleotide exchange factors (GEFs) in a mouse xenograft model. LUNA18 shows significant cellular efficacy against cell lines with KRAS genetic alterations, such as colon cancer, stomach cancer, non-small cell lung cancer and pancreaticcancer[1][2][3]. Uses: Scientific research. Group: Peptides. Alternative Names: Paluratide. CAS No. 2676177-63-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-156002. | |
| Lunasin | Lunasin is a bioactive peptide with antioxidant, anti-inflammatory, anticancer and anti-aging properties. Lunasin can be isolated from soybean. Lunasin also has an epigenetic mechanism of action associated with histone acetylation. Lunasin can be internalized into cells and inhibit Oncosphere formation in cancer cells [1]. Uses: Scientific research. Group: Peptides. CAS No. 496823-34-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P5285. | |
| lunresertib | lunresertib (RP-6306) is a potent, selective and orally active PKMYT1 inhibitor with an IC 50 of 14 nM. lunresertib shows a high degree of selectivity over other kinases in cellular binding assays. lunresertib shows anticancer effects [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RP-6306. CAS No. 2719793-90-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145817A. | |
| Lunsekimig | Lunsekimig is an anti- TSLP/IL13/ALB monoclonal antibody composed of 5 sequentially linked variable region heavy chains [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2770858-49-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990748. | |
| Lupanine | Lupanine (D-Lupanine) is a natural ketonic derivative of Sparteine ( (+)-Sparteine (HY-W008350) ) with a ganglioplegic activity. Lupanine shows binding affinity for nicotinic receptor ( nAChR ) with a K i value of 500 nM [1]. Uses: Scientific research. Group: Natural products. Alternative Names: D-Lupanine. CAS No. 550-90-3. Pack Sizes: 1 mg. Product ID: HY-N3359. | |
| Lupenone | Lupenone is an orally active lupine-type triterpenoid that can be isolated from Musa basjoo. Lupenone Lupenone plays a role through the PI3K/Akt/mTOR and NF-κB signaling pathways. Lupenone has anti-inflammatory, antiviral , antidiabetic and anticancer activities [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 1617-70-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N2590. | |
| Lupeol | Lupeol (Clerodol; Monogynol B; Fagarasterol) is an active pentacyclic triterpenoid, has anti-oxidant, anti-mutagenic, anti-tumor and anti-inflammatory activity. Lupeol is a potent androgen receptor (AR) inhibitor and can be used for cancer research, especially prostate cancer of androgen-dependent phenotype (ADPC) and castration resistant phenotype (CRPC) [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Clerodol; Monogynol B; Fagarasterol. CAS No. 545-47-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0790. | |
| Lupeol acetate | Lupeol acetate is a derivative of Lupeol. Lupeol acetate is an anti-inflammatory , antibacterial , anti-trypanosomic and anticancer agent with oral activity. Lupeol acetate significantly improves the symptoms of rheumatoid arthritis by down-regulating the expression of inflammatory cytokines and osteoclast production. Lupeol acetate inhibits spermatogenesis in male rats and eventually led to infertility [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 1617-68-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-126114. | |
| (-)-Lupinine | (-)-Lupinine is a quinolizidine alkaloid. Uses: Scientific research. Group: Signaling pathways. CAS No. 486-70-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-121219. | |
| Lupulone | Lupulone is a beta-acid from the hop plant H. lupulus with diverse biological activities including antibacterial, antioxidant, and anticarcinogenic properties [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 468-28-0. Pack Sizes: 1 mg. Product ID: HY-124923. | |
| Lurasidone | Lurasidone (SM-13496) is an antagonist of both dopamine D 2 and 5-HT 7 with IC 50 s of 1.68 and 0.495 nM, respectively. Lurasidone (SM-13496) is also a partial agonist of 5-HT 1A receptor with an IC 50 of 6.75 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SM-13496. CAS No. 367514-87-2. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-B0032A. | |
| Lurasidone Hydrochloride | Lurasidone (Hydrochloride) (SM-13496 (Hydrochloride)) is an antagonist of both dopamine D 2 and 5-HT 7 with IC 50 s of 1.68 and 0.495 nM, respectively. Lurasidone (Hydrochloride) (SM-13496 (Hydrochloride)) is also a partial agonist of 5-HT 1A receptor with an IC 50 of 6.75 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SM-13496 Hydrochloride. CAS No. 367514-88-3. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-B0032. | |
| Lurbinectedin | Lurbinectedin (PM01183) is a DNA minor groove covalent binder with potent anti-tumour activity; inhibits RMG1 and RMG2 cell growth with IC 50 values of 1.25 and 1.16 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PM01183; LY-01017. CAS No. 497871-47-3. Pack Sizes: 100 μg; 1 mg; 2 mg; 5 mg. Product ID: HY-16293. | |
| Lurtotecan | Lurtotecan (GI147211; OSI-211), a semisynthetic Camptothecin analog, is a topoisomerase I inhibitor. Lurtotecan has anticancer effects [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GI147211; OSI-211. CAS No. 149882-10-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13670. | |
| Lusaperidone | Lusaperidone (R107474) is an α2 adrenergic receptor antagonist with K i s of 0.13 and 0.15 nM for α2A and α2C, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R107474. CAS No. 214548-46-6. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-U00117. | |
| Luseogliflozin | Luseogliflozin (TS 071) is a potent, selective, orally active sodium-dependent glucose cotransporter (SGLT) 2 inhibitor, with an IC 50 of 2.26 nM, about 1765-fold selectivity over SGLT1 ( IC 50 , 3990 nM). Luseogliflozin has the protential for researching type 2 diabetes [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TS 071. CAS No. 898537-18-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10449. | |
| Luseogliflozin hydrate | Luseogliflozin (TS 071) hydrate is a selective potent and orally active second-generation sodium-glucose co-transporter 2 ( SGLT2 ) inhibitor with an IC 50 ?of?2.26 nM. Luseogliflozin hydrate can be used for the research of type 2 diabetes mellitus (T2DM) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TS 071 hydrate. CAS No. 1152425-66-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10449A. | |
| Luspatercept | Luspatercept (ACE-536) is a recombinant modified ActRIIB fusion protein that binds with transforming growth factor β superfamily ligands. Luspatercept increases the erythrocyte numbers and promotes maturation of erythroid precursors. Luspatercept binds with GDF11 and inhibits Smad2/3 signaling. Luspatercept can be used for the research of anemia [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ACE-536; luspatercept - aamt. CAS No. 1373715-00-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99720. | |
| Lusutrombopag | Lusutrombopag is an orally bioavailable thrombopoietin (TPO) receptor agonist, used for treatment of chronic liver disease. Uses: Scientific research. Group: Signaling pathways. Alternative Names: S-888711. CAS No. 1110766-97-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19883. | |
| Lusvertikimab | Lusvertikimab (OSE-127) is a humanized IL7R monoclonal antibody. Lusvertikimab is not internalized by target cells and prevents IL7R heterodimerization and subsequent downstream signaling. Lusvertikimab has anti-leukemic efficacy and has the potential for B cell precursor acute lymphoblastic leukemia (BCP-ALL) research [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: OSE-127. CAS No. 2375835-91-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99412. | |
| LUT014 | LUT014 is a B-Raf inhibitor with an IC 50 of 11.7 nM, and developed to reduce dose-limiting acneiform lesions associated EGFR Inhibitors treatment. Extracted from patent WO 2019026065A2 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2274819-46-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111940. | |
| Lutein | Lutein (Xanthophyll) is a carotenoid with reported anti-inflammatory properties. A large body of evidence shows that lutein has several beneficial effects, especially on eye health [1]. Lutein exerts its biological activities, including anti-inflammation, anti-oxidase and anti- apoptosis , through effects on reactive oxygen species (ROS) [2] [3]. Lutein is able to arrive in the brain and shows antidepressant-like and neuroprotective effects. Lutein is orally active [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Xanthophyll. CAS No. 127-40-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N6947. | |
| Luteinizing hormone (human) | Luteinizing hormone (human), a heterodimeric glycoprotein hormone produced by the pituitary gland (LH), plays key roles in human reproduction [1]. Uses: Scientific research. Group: Peptides. CAS No. 39341-83-8. Pack Sizes: 10 μg; 50 μg. Product ID: HY-P2293. | |
| Luteolin | Luteolin (Luteoline), a flavanoid compound, is a potent Nrf2 inhibitor. Luteolin has anti-inflammatory, anti-cancer properties, including the induction of apoptosis and cell cycle arrest, and the inhibition of metastasis and angiogenesis, in several cancer cell lines, including human non-small lung cancer cells [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Luteoline; Luteolol; Digitoflavone. CAS No. 491-70-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-N0162. | |
| Luteolin 7-O-glucuronide | Luteolin 7-O-glucuronide could inhibit Matrix Metalloproteinases (MMP) activities, with IC 50 s of 17.63, 7.99, 11.42, 12.85, 0.03 μM for MMP-1, MMP-3, MMP-8, MMP-9, MMP-13, respectively [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Luteolin 7-glucuronide. CAS No. 29741-10-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N1463. | |
| Luteolin monohydrate | Luteolin (monohydrate) is the monohydrate of Luteolin. Luteolin (Luteoline), a flavonoid, is also a potent Nrf2 inhibitor. Luteolin has anti-inflammatory and anticancer properties, induces apoptosis and cell cycle arrest in multiple human cancer cell lines, including non-small lung cancer cells, and inhibits cell metastasis and angiogenesis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 6113-16-2. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-W303895. | |
| Lutikizumab | Lutikizumab (ABT-981) is an anti- IL-1α and IL-1β dual variable domain immunoglobulin. Lutikizumab binds and inhibits IL-1α and IL-1&beta. Lutikizumab can be used for the research of osteoarthritis [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ABT-981. CAS No. 1791411-57-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99721. | |
| Luvadaxistat | Luvadaxistat (TAK-831) is an orally active, highly selective, potent D-amino acid oxidase (DAAO) inhibitor. Luvadaxistat inhibits oxidative deamination of D-serine via the human recombinant DAAO enzyme with an IC 50 of 14 nM. Luvadaxistat significantly increases D-serine levels in the rodent brain, plasma, and cerebrospinal fluid. Luvadaxistat has the potential for schizophrenia research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TAK-831. CAS No. 1425511-32-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109183. | |
| Luveltamab | Luveltamab is an anti- FOLR1 human IgG1 κ monoclonal antibody [1]. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001). Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2484883-56-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990687. | |
| Luvixasertib hydrochloride | CFI-402257 hydrochloride is a highly selective and orally bioavailable TTK/Mps1 inhibitor with an IC50 of 1.7 nM for TTK in vitro. CFI-402257 hydrochloride has anti-cancer activity[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CFI-402257 hydrochloride. CAS No. 1610677-37-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101340A. | |
| Luxdegalutamide | Luxdegalutamide (ARV-766) is an orally active protein hydrolysis targeted chimeric (PROTAC) targeting androgen receptor (AR), which can degrade AR resistance related mutants, including T878/H875/L702 mutants. Luxdegalutamide has anti-tumor activity and can be used in the study of castration resistant prostate cancer[1][2].. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ARV-766. CAS No. 2750830-09-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153342. | |
| Luxeptinib | Luxeptinib (CG-806) is an orally active, reversible, first-in-class, non-covalent and potent pan-FLT3/pan-BTK inhibitor. Luxeptinib induces cell cycle arrest, apoptosis or autophagy in acute myeloid leukemia cells[1][2][3][4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CG-806. CAS No. 1616428-23-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139535. | |
| Luzindole | Luzindole (N-0774) is a selective melatonin receptor antagonist. Luzindole preferentially targets MT2 (Mel 1b ) over MT1 (Mel 1a ) with K i values of 10.2 and 158 nM for human MT2 and MT1, respectively. Luzindole suppresses experimental autoimmune encephalomyelitis (EAE), and exerts antidepressant-like activity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: N-0774. CAS No. 117946-91-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-101254. | |
| L-Valine | L-Valine (Valine) is a new nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Valine. CAS No. 72-18-4. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-N0717. | |
| L-Valine-1-13C | L-Valine-1- 13 C is the 13 C-labeled L-Valine. L-Valine is one of 20 proteinogenic amino acids. L-Valine is an essential amino acid[1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 81201-85-6. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0717S4. | |
| L-Valine-13C5 | L-Valine- 13 C 5 is the 13 C-labeled L-Valine. L-Valine is one of 20 proteinogenic amino acids. L-Valine is an essential amino acid[1]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: Valine- 13 C5. CAS No. 55443-52-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N0717S6. | |
| L-Valine-13C5,15N | L-Valine- 13 C 5 , 15 N is the 13 C- and 15 N-labeled L-Valine. L-Valine is one of 20 proteinogenic amino acids. L-Valine is an essential amino acid[1]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: Valine- 13 C5, 15 N. CAS No. 202407-30-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N0717S1. | |
| L-Valine (Standard) | L-Valine (Standard) is the analytical standard of L-Valine. This product is intended for research and analytical applications. L-Valine (Valine) is a new nonlinear semiorganic material. L-Valine standrd causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine standrd inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 72-18-4. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0717R. | |
| L-Valyl-L-phenylalanine | L-Valyl-L-phenylalanine (Valylphenylalanine; H-VAL-PHE-OH) has been reported as biocompatible polymer. Uses: Scientific research. Group: Natural products. Alternative Names: Valylphenylalanine; H-VAL-PHE-OH. CAS No. 3918-92-1. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-107378. | |
| Lvguidingan | Lvguidingan is a potent anticonvulsant agent. Lvguidingan also has sedative-hypnotic, tranquilizing, and muscle-relaxing actions. Lvguidingan can be used as antiepileptic agent [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Anticonvulsant 7903. CAS No. 82351-05-1. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-100377. | |
| LW3 | LW3 is a potent antifungal agent. LW3 has antifungal activity with EC 50 values of 0.54, 0.09, 1.52, and 2.65 mg/L against B. cinerea , R. solani , S. sclerotiorum , and F. graminearum , respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2803367-68-0. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-155703. | |
| LW6 | LW6 (HIF-1? inhibitor) is a novel HIF-1 inhibitor with an IC50 value of 4.4 ?M, and it is also an inhibitor of MDH2. LW6 decreases HIF-1? protein expression without affecting HIF-1? expression. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HIF-1? inhibitor; LW8. CAS No. 934593-90-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13671. | |
| LX1 | LX1 is an anti-prostate cancer compound that targets androgen receptor ( AR ), AR variants and steroidogenic enzyme AKR1C3. LX1 inhibits the enzymatic activity of AKR1C3 , reduces the conversion of androstenedione to testosterone and reduces the expression of AR and AR-V7 and downregulates their target genes. LX1 overcomes the resistance of tumor cells to Enzalutamide (HY-70002), and the combination with Enzalutamide (HY-70002) further inhibits tumor growth [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2647877-84-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-163940. | |
| LX-1031 | LX-1031 is a potent, orally available tryptophan 5-hydroxylase (TPH) inhibitor that reduces serotonin (5-HT) synthesis peripherally. Uses: Scientific research. Group: Signaling pathways. CAS No. 945976-76-1. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13041. | |
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