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L-Leucine-13C6
Leucine- 13 C 6 is the 13 C-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway[1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 201740-84-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N0486S2.
L-Leucine-13C6,15N
L-Leucine- 13 C 6 , 15 N is the 13 C- and 15 N-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway[1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 202406-52-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N0486S8.
L-Leucine-7-amido-4-methylcoumarin hydrochloride
L-Leucine-7-amido-4-methylcoumarin (Leu-AMC) hydrochloride is a bright blue fluorogenic peptidyl substrate for LAP3 (leucine aminopeptidase). L-Leucine-7-amido-4-methylcoumarin hydrochloride can be used for leucine aminopeptidase inhibition assays in vitro [1]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Leu-AMC hydrochloride. CAS No. 62480-44-8. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-137844.
L-Leucine-d10
L-Leucine-d 10 is the deuterium labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway[1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 106972-44-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N0486S.
L-Leucine-d3
L-Leucine-d3 is the deuterium labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway[1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 87828-86-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0486S9.
L-Leucinol
L-Leucinol ((+)-Leucinol) is a competitive aminopeptidase inhibitor with K i value of 17 μM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (+)-Leucinol. CAS No. 7533-40-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-W015876.
L-Leucyl-L-Leucine methyl ester hydrobromide
L-Leucyl-L-Leucine methyl ester (LLOMe) hydrobromide, a dipeptide condensation product of L-leucine methyl ester generated by human monocytes or polymorphonuclear leukocytes, selectively eliminates lymphocytes with cytotoxic potential. L-Leucyl-L-Leucine methyl ester hydrobromide also can induce endolysosomal pathway stress [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: LLOMe hydrobromide; Leu-Leu methyl ester hydrobromide; H-Leu-Leu-OMe hydrobromide. CAS No. 16689-14-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129905A.
L-Leucyl-L-Leucine methyl ester hydrochloride
L-Leucyl-L-Leucine methyl ester (LLOMe) hydrochloride, a dipeptide condensation product of L-leucine methyl ester generated by human monocytes or polymorphonuclear leukocytes, selectively eliminates lymphocytes with cytotoxic potential. L-Leucyl-L-Leucine methyl ester hydrochloride also can induce endolysosomal pathway stress [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: LLOMe hydrochloride; Leu-Leu methyl ester hydrochloride; H-Leu-Leu-OMe hydrochloride. CAS No. 6491-83-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg. Product ID: HY-129905.
L-Linalool
L-Linalool, a monoterpene with sedative and anxiolytic potential, has been used in Parkinson's disease research [1]. Uses: Scientific research. Group: Natural products. Alternative Names: (-)-Linalool. CAS No. 126-91-0. Pack Sizes: 100 mg; 500 mg. Product ID: HY-116195.
LLK203
LLK203 is a potent USP2/USP8 dual-target inhibitor with IC50s of 0.89 ?M and 0.52 ?M, respectively. LLK203 leads a degradation of ER? and induces apoptosis of breast cancer MCF-7 cells. LLK203 demonstrates antitumor activities against the 4T1 tumor mice model[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2758090-62-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-162312.
LLL12
LLL12 is a small molecule inhibitor of STAT3 that inhibits STAT3 phosphorylation. LLL12 enhanced the inhibitory effect of Cisplatin (HY-17394) and Paclitaxel (HY-B0015) on ovarian cancer cell formation, migration, and growth[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1260247-42-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-19536.
LLY-283
LLY-283 is a potent, selective and oral protein arginine methyltransferase 5 ( PRMT5 ) inhibitor, with an IC 50 of 22 nM and a K d of 6 nM for PRMT5:MEP50 complex, and shows antitumor activity. Uses: Scientific research. Group: Signaling pathways. CAS No. 2040291-27-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-107777.
LLY-507
LLY-507 is a potent and selective inhibitor of protein-lysine methyltransferase SMYD2. LLY-507 potently inhibits the ability of SMYD2 to methylate p53 peptide with an IC50 <15 nM. LLY-507 serves as a valuable chemical probe to aid in the dissection of SMYD2 function in cancer and other biological processes[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1793053-37-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-19313.
L-Lysine
L-lysine is an essential amino acid for humans with orally activity. L-lysine can inhibit the occurrence of HSV infections and is used in herpes research. L-lysine increases calcium absorption, reduces diabetes-related diseases, improves gut health, and alleviates pancreatic inflammation. L-lysine can be used in research on metabolism, infection, and inflammation [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 56-87-1. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-N0469.
L-Lysine-13C6,15N2 dihydrochloride
L-Lysine- 13 C 6 , 15 N 2 (dihydrochloride) is a 15 N-labeled and 13 C-labled L-Lysine dihydrochloride[1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 202406-54-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-W009762S.
L-Lysine-13C6,15N2 hydrochloride
L-Lysine- 13 C 6 , 15 N 2 (hydrochloride) is the 13 C- and 15 N-labeled L-Lysine hydrochloride. L-lysine hydrochloride is an essential amino acid for humans with various benefits including treating herpes, increasing calcium absorption, reducing diabetes-related illnesses and improving gut health. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 1200447-00-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N0470S3.
L-Lysine-13C6 dihydrochloride
L-Lysine- 13 C 6 (dihydrochloride) is the 13 C-labeled L-Lysine dihydrochloride. L-lysine dihydrochloride is an essential amino acid[1][2] with important roles in connective tissues and carnitine synthesis, energy production, growth in children, and maintenance of immune functions[2]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 201740-81-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N0469S1.
L-Lysine-15N2 hydrochloride
L-Lysine- 15 N 2 (hydrochloride) is the 15 N-labeled L-Lysine hydrochloride. L-lysine hydrochloride is an essential amino acid for humans with various benefits including treating herpes, increasing calcium absorption, reducing diabetes-related illnesses and improving gut health. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 1217460-44-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N0470S.
L-Lysine-15N dihydrochloride
L-Lysine- 15 N dihydrochloride is a 15 N-labeled L-Lysine dihydrochloride[1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 204451-50-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-W009762S7.
L-Lysine α-oxidase
L-Lysine α-oxidase is a potent anticancer agent. L-Lysine α-oxidase also a L-amino acid oxidase, deaminates L-lysine with the yield of H2O2, ammonia, and α -keto-ε -aminocaproate. L-Lysine α-oxidase shows cytotoxicity and anticancer activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 70132-14-8. Pack Sizes: 25 U. Product ID: HY-P2965.
L-Lysine-d4 dihydrochloride
L-Lysine-d 4 (dihydrochloride) is the deuterium labeled L-Lysine dihydrochloride[1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 203633-22-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-W009762S2.
L-Lysine-d4 hydrochloride
L-Lysine-d 4 (hydrochloride) is the deuterium labeled L-Lysine. L-lysine hydrochloride is an essential amino acid for humans with various benefits including treating herpes, increasing calcium absorption, reducing diabetes-related illnesses and improving gut health. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 284664-96-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N0470S6.
L-Lysine-d9 hydrochloride
L-Lysine-d 9 (hydrochloride) is the deuterium labeled L-Lysine. L-lysine hydrochloride is an essential amino acid for humans with various benefits including treating herpes, increasing calcium absorption, reducing diabetes-related illnesses and improving gut health. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 2708343-64-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N0470S5.
L-Lysine hydrate
L-Lysine hydrate is an essential amino acid. L-Lysine hydrate can be research for vascular calcification (VC) and acute pancreatitis [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 39665-12-8. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-W015370.
L-Lysine hydrochloride
L-lysine hydrochloride is an essential amino acid for humans with various benefits including treating herpes, increasing calcium absorption, reducing diabetes-related illnesses and improving gut health. Uses: Scientific research. Group: Natural products. CAS No. 657-27-2. Pack Sizes: 10 mM * 1 mL; 1 g. Product ID: HY-N0470.
L-Lysine (Standard)
L-Lysine (Standard) is the analytical standard of L-Lysine. This product is intended for research and analytical applications. L-lysine is an essential amino acid for humans with orally activity. L-lysine can inhibit the occurrence of HSV infections and is used in herpes research. L-lysine increases calcium absorption, reduces diabetes-related diseases, improves gut health, and alleviates pancreatic inflammation. L-lysine can be used in research on metabolism, infection, and inflammation [1] [2] [3] [4]. IC 50 & Target:L-lysine (150 mg/kg) promotes, but not initiates, bladder cancer. The administration of L-lysine to rats submitted to colovesical cystoplasty accelerates the development of transitional metaplasia of the intestinal epithelium [1]. L-lysine (10 mg/kg) treatment attenuates pancreatic tissue injury induced by L-arginine by inhibiting the release of the inflammatory cytokine IL-6 and enhance antioxidant activity [2]. In Vivo: L-lysine (10 mg/kg, p.o., pre-treated or post-treated, administration duration 15 days) treatment attenuates pancreatic tissue injury induced by L-arginine by inhibiting the release of the inflammatory cytokine IL-6 and enhance antioxidant activity in acute pancreatitis mice model [1]. L-lysine (5 or 10 mg/kg, p.o., 45 days) ameliorates sepsis-induced acute lung injury in a lipopolysaccharide (HY-D1056)-induced mouse model [3]. Uses: Scientific research. Group: Natural products. CAS No
LM-030
LM-030 (BPR277) is a potent kallikrein-related peptidase 7 (KLK7) and epidermal elastase 2 (ELA2) inhibitor with IC 50 s of 6 nM and 55 nM, respectively(Example 4) [1]. LM-030 can be used for the study of Netherton syndrome [2]. Uses: Scientific research. Group: Peptides. Alternative Names: BPR277. CAS No. 1122484-55-2. Pack Sizes: 1 mg. Product ID: HY-P4669.
LM10
LM10 is a potent inhibitor of tryptophan 2,3-dioxygenase ( TDO ). Tryptophan 2,3-dioxygenase (TDO) is an unrelated hepatic enzyme that also degrades tryptophan along the kynurenine pathway. LM10 has the potential for the research of cancer diseases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1316695-35-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-33298.
LM11A-31
LM11A-31, a non-peptide p75 NTR (neurotrophin receptor p75) modulator, is an orally active and potent proNGF (nerve growth factor) antagonist. LM11A-31 is an amino acid derivative with high blood-brain barrier permeability and blocks p75-mediated cell death. LM11A-31 reverses cholinergic neurite dystrophy in Alzheimer's disease mouse models with mid- to late-stage disease progression [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 102562-74-3. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-117088.
LM11A-31 dihydrochloride
LM11A-31 dihydrochloride, a non-peptide p75 NTR (neurotrophin receptor p75) modulator, is an orally active and potent proNGF (nerve growth factor) antagonist. LM11A-31 dihydrochloride is an amino acid derivative with high blood-brain barrier permeability and blocks p75-mediated cell death. LM11A-31 dihydrochloride reverses cholinergic neurite dystrophy in Alzheimer's disease mouse models with mid- to late-stage disease progression [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1243259-19-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-110155.
LM22A-4
LM22A-4 is a specific agonist of tyrosine kinase receptor B , used for neurological disease research. Uses: Scientific research. Group: Signaling pathways. CAS No. 37988-18-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100673.
LM22B-10
LM22B-10 is an activator of TrkB/TrkC neurotrophin receptor, and can induce TrkB, TrkC, AKT and ERK activation in vitro and in vivo. Uses: Scientific research. Group: Signaling pathways. CAS No. 342777-54-2. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-104047.
LM-41
LM-41 is a Flufenamic acid-derived TEAD inhibitor hat strongly reduce the expression of CTGF, Cyr61, Axl and NF2. LM-41 inhibits migration of human MDA-MB-231 breast cancer cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2996821-30-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-155309.
LMD-009
LMD-009 is a selective CCR8 nonpeptide agonist. LMD-009 mediates chemotaxis, inositol phosphate accumulation, and calcium release in high potencies with EC50s from 11 to 87 nM[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 950195-51-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-121885.
L-Methioninamide hydrochloride
L-Methioninamide hydrochloride, a Methionine analogue, is Methionyl-tRNA synthetase inhibitor [1]. Uses: Scientific research. Group: Peptides. CAS No. 16120-92-6. Pack Sizes: 10 mM * 1 mL; 5 g; 10 g. Product ID: HY-W016256.
L-Methionine
L-Methionine is an L-isomer of orally active Methionine, an essential amino acid. Methionine is a strong liver antidote that acts as a liver protector. L-Methionine can inhibit cell proliferation and induce cell apoptosis. L-Methionine has antitumor and antioxidant activity [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 63-68-3. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-N0326.
L-Methionine-13C
L-Methionine- 13 C is the 13 C-labeled L-Methionine. L-Methionine is the L-isomer of Methionine, an essential amino acid for human development. Methionine acts as a hepatoprotectant. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 49705-26-2. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-N0326S3.
L-Methionine-15N
L-Methionine- 15 N is the 15 N-labeled L-Methionine. L-Methionine is the L-isomer of Methionine, an essential amino acid for human development. Methionine acts as a hepatoprotectant. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 82572-25-6. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-N0326S.
L-Methionine-d3
L-Methionine-d 3 is the deuterium labeled L-Methionine. L-Methionine is the L-isomer of Methionine, an essential amino acid for human development. Methionine acts as a hepatoprotectant. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 13010-53-2. Pack Sizes: 50 mg; 100 mg. Product ID: HY-N0326S7.
L-Methionine-DL-sulfoximine
L-Methionine-DL-sulfoximine (MSX; MSO), a highly specific and irreversible inhibitor of Glutamine synthetase (GS), is also a potent convulsant which metabolically and morphologically primarily affects astroglia. L-Methionine-DL-sulfoximine has been employed to inhibit the Gln-dependent ammonia-stimulated neuronal toxicity in vitro, potentiating Gln deficit-dependent depression. L-Methionine-DL-sulfoximine tremendously increases the rate of release of fixed nitrogen in cyanobacteria. L-Methionine-DL-sulfoximine is a promising candidate for research in biofertilizers and convulsive seizures (CS)[1][2][3][4][5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MSX; MSO. CAS No. 15985-39-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-B1692.
L-Methionine sulfone
L-Methionine sulfone is a sulfonic acid derivative of L-Methionine (HY-N0326). L-Methionine in the presence of a number of oxidizing systems is readily converted to L-Methionine sulfone [1]. Uses: Scientific research. Group: Peptides. CAS No. 7314-32-1. Pack Sizes: 100 mg. Product ID: HY-W097491.
L-Methionine sulfoxide
L-Methionine sulfoxide is an orally active oxidation product of Methionine (HY-N0326). L-Methionine sulfoxide can be partially converted into Methionine in the body and participate in the synthesis of glutathione in the liver. L-Methionine sulfoxide provides the body with sulfur activity and can participate in the synthesis of proteins and sulfur-containing compounds [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: H-Met(O)-OH. CAS No. 3226-65-1. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-W010104.
LMK-235
LMK-235 is a potent and selective HDAC4/5 inhibitor, inhibits HDAC5, HDAC4, HDAC6, HDAC1, HDAC2, HDAC11 and HDAC8, with IC50s of 4.22 nM, 11.9 nM, 55.7 nM, 320 nM, 881 nM, 852 nM and 1278 nM, respectively, and is used in cancer research. Uses: Scientific research. Group: Signaling pathways. CAS No. 1418033-25-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-18998.
LMP744
LMP744 (MJ-III65) is a DNA intercalator and Topoisomerase I (Top1) inhibitor with antitumor activity[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MJ-III65; NSC706744. CAS No. 308246-52-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-U00248.
LMT-28
LMT-28 is an orally active and the first synthetic IL-6 inhibitor that functions through direct binding to gp130. LMT-28 shows low toxicity and selectively inhibits IL-6-induced phosphorylation of STAT3, JAK2, and gp130[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1239600-18-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-102084.
L-NAME hydrochloride
L-NAME hydrochloride inhibits NOS with an IC 50 of 70 μM. L-NAME is a precursor to NOS inhibitor L-NOARG which has an IC 50 value of 1.4 μM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NG-Nitroarginine methyl ester hydrochloride. CAS No. 51298-62-5. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-18729A.
l-Naproxen
l-Naproxen ((R)-Naproxen) is an enantiomer of (S)-Naproxen. l-Naproxen can inhibit Cdc42 and Rac1 ( EC 50 =96 μM and 212 μM, respectively), and show anti-tumor activity. l-Naproxen is a nonsteroidal antiinflammatory agent (NSAID) [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (R)-Naproxen. CAS No. 23979-41-1. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-15031.
L-NIL
L-NIL is an inducible NO synthase inhibitor, with an IC50 of 3.3 ?M for miNOS[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 53774-63-3. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-12116.
L-NIO dihydrochloride
L-NIO dihydrochloride is a potent, non-selective and NADPH-dependent nitric oxide synthase (NOS) inhibitor, with K i s of 1.7, 3.9, 3.9 μM for neuronal (nNOS), endothelial (eNOS), and inducible (iNOS), respectively [1] [2]. L-NIO dihydrochloride induces a consistentfocal ischemic infarctin rats [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 159190-44-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-100986.
L-NMMA acetate
L-NMMA acetate is a nitric oxide synthase inhibitor of all NOS isoforms including NOS1, NOS2, and NOS3. The K i values for nNOS (rat), eNOS (human), and iNOS (mouse) are approximately 0.18, 0.4, and 6 μM, respectively. Uses: Scientific research. Group: Natural products. Alternative Names: Tilarginine acetate; Methylarginine acetate. CAS No. 53308-83-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-18732A.
L-Norleucine
L-Norleucine ((S)-2-Aminohexanoic acid) is an isomer of leucine, specifically affects protein synthesis in skeletal muscle, and has antivirus activity. Uses: Scientific research. Group: Natural products. Alternative Names: (S)-2-Aminohexanoic acid; (S)-Norleucine. CAS No. 327-57-1. Pack Sizes: 1 g. Product ID: HY-Y0017.
L-Norvaline
L-Norvaline is the inhibitor for arginase , that promotes the production of NO, reduces oxidative stress, improves insulin resistance, and exhibits antioxidant and anti-hyperglycemic effects. L-Norvaline can be used in research of Alzheimers disease [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Norvaline. CAS No. 6600-40-4. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-Y0399.
Lobaplatin
Lobaplatin (D-19466) is a diastereometric mixture of platinum(II) complexe. Lobaplatin arrests cell cycle at G1 and G2/M phase. Lobaplatin induces apoptosis by increasing expressions of caspase and Bax, decreasing expression of Bcl-2. Lobaplatin can be used for research of cancer [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: D-19466. CAS No. 135558-11-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-105930.
Lobeglitazone
Lobeglitazone is a new type of thiazolidinedione. Lobeglitazone is the orally active agonist for PPAR with EC 50 of 137.4 nM and 546.3 nM for PPARγ and PPAR&alpha. Lobeglitazone is the inhibitor for ERK/JNK/Smad/NF-κB signaling pathway. Lobeglitazone exhibits anti-inflammatory, anti-diabetic, anti-fibrotic and anti-atherosclerotic properties [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. CAS No. 607723-33-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14928.
Lobeglitazone sulfate
Lobeglitazone sulfate is a new type of thiazolidinedione. Lobeglitazone sulfate is the orally active agonist for PPAR with EC 50 of 137.4 nM and 546.3 nM for PPARγ and PPAR&alpha. Lobeglitazone sulfate is the inhibitor for ERK/JNK/Smad/NF-κB signaling pathway. Lobeglitazone sulfate exhibits anti-inflammatory, anti-diabetic, anti-fibrotic and anti-atherosclerotic properties [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. CAS No. 763108-62-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14928A.
Lobeline hydrochloride
Lobeline (α-Lobeline) hydrochloride is a brain-penetrant nicotinic receptor agonist. Lobeline hydrochloride increases dopamine (DA) release by inhibiting DA uptake into synaptic vesicles, and altering presynaptic DA storage. Lobeline hydrochloride is effective in smoking cessation [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: α-Lobeline hydrochloride; L-Lobeline hydrochloride. CAS No. 134-63-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0979.
Lobenzarit disodium (CCA) is an anti-arthritic and anti-oxidative agent [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CCA. CAS No. 64808-48-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107360.
Lobradimil
Lobradimil (RMP 7), a synthetic bradykinin analog, is a potent and selective bradykinin B2 receptor agonist (Ki: 0.54 nM). Lobradimil increases the permeability of the BBB. Lobradimil can be used in the research of brain tumors[1]. Uses: Scientific research. Group: Peptides. Alternative Names: RMP 7. CAS No. 159768-75-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-105155.
LOC14
LOC14 is a potent Protein disulfide isomerase (PDI) inhibitor with EC50 and Kd values of 500 nM and 62 nM, respectively. LOC14 exhibits high stability in mouse liver microsomes and blood plasma, low intrinsic microsome clearance, and low plasma-protein binding[1].LOC14 inhibits PDIA3 activity, decreases intramolecular disulfide bonds and subsequent oligomerization (maturation) of HA in lung epithelial cells[3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 877963-94-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100432.
Locostatin
Locostatin (UIC-1005) is a potent RKIP inhibitor. Locostatin binds Raf kinase inhibitor RKIP protein and disrupts the interaction of RKIP with Raf-1 kinase and G protein-coupled receptor kinase 2. Locostatin inhibits cell proliferation and migration. Locostatin can be used to synthesize chemical probes toward PEBP-proteins. Locostatin aggravates thioacetamide (HY-Y0698)-induced acute liver failure in mice [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: UIC-1005. CAS No. 90719-30-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-W013411A.
L-Octanoylcarnitine
L-Octanoylcarnitine is a plasma metabolite and a physiologically active form of octanoylcarnitine. L-Octanoylcarnitine can be used for the research of breast cancer [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 25243-95-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-113161.
L-Octanoylcarnitine hydrochloride
L-Octanoylcarnitine hydrochloride is a plasma metabolite and a physiologically active form of octanoylcarnitine. L-Octanoylcarnitine hydrochloride can be used for the research of breast cancer [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 54377-02-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-W354498.
Locustatachykinin I
Locustatachykinin I is a insect tachykinin-related peptide isolated from Locusta migratoria. Locustatachykinin I exhibits sequence homologies with the vertebrate tachykinins. In Lacanobia, Locustatachykinin I is also a substrate for a deamidase [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 126985-97-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1183.
Locust bean gum, from Ceratonia siliqua seeds
Locust bean gum is a natural polysaccharide derived from the seeds of the carob tree. It is commonly used as a thickening, stabilizing and gelling agent in a variety of foods, including dairy, baked goods and meat products. Locust bean gum has several properties suitable for these applications, including high water retention capacity, ability to form stable gels at low temperatures, and resistance to acidic conditions. Additionally, it can be used as a dietary fiber supplement due to its potential health benefits, including improving digestion and lowering cholesterol levels. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Locust bean gum, Polysaccharide>75%, 5000-6500 mPa·S. CAS No. 9000-40-2. Pack Sizes: 50 mg; 100 mg. Product ID: HY-W250146.
Lodenafil
Lodenafil is a potent phosphodiesterase type 5 (PDE5) inhibitor for the treatment of erectile dysfunction (ED) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Hydroxyhomosildenafil. CAS No. 139755-85-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123210.
Lodenafil carbonate
Lodenafil carbonate, a dimer that acts as a proagent delivering Lodenafil in vivo, is an orally active phosphodiesterase type 5 (PDE5) inhibitor for the treatment of erectile dysfunction (ED) [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 398507-55-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg. Product ID: HY-108045.
Lodoxamide
Lodoxamide (U-42585E free acid) is an antiallergic compound acting as a mast-cell stabilizer for the treatment of asthma and allergic conjunctivitis. Uses: Scientific research. Group: Signaling pathways. Alternative Names: U-42585E free acid. CAS No. 53882-12-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-14270.
Lodoxamide tromethamine
Lodoxamide tromethamine (U-42585E) is a medication for the treatment of prophylaxis of mast cell-mediated allergic disease. Uses: Scientific research. Group: Signaling pathways. Alternative Names: U-42585E. CAS No. 63610-09-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16289.
Lofepramine
Lofepramine (Lopramine) is a modified tricyclic and orally active antidepressant. Lofepramine inhibits the uptake of Noradrenaline (NA) (HY-13715) and 5-hydroxytryptamine (5-HT) with IC 50 s of 2.7 μM and 11 μM, respectively. Lofepramine exerts its antidepressant activity by promoting noradrenergic neurotransmission. Lofepramine also enhances serotonergic neurotransmission by inhibiting neuronal uptake of 5-HT and tryptophan pyrrolase. Lofepramine exhibits significant anxiolytic properties. [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Lopramine. CAS No. 23047-25-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12390.