MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Oleuropein | Oleuropein, found in olive leaves and oil, exerts antioxidant, anti-inflammatory and anti-atherogenic effects through direct inhibition of PPARγ transcriptional activity [1]. Oleuropein induces apoptosis in breast cancer cells via the p53-dependent pathway and through the regulation of Bax and Bcl2 genes. Oleuropein also inhibits aromatase [2]. Uses: Scientific research. Group: Natural products. CAS No. 32619-42-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0292. |  |
| Oleuropein Aglycone | Oleuropein Aglycone (3,4-DHPEA-EA) is a polyphenol and the aglycone form of oleuropein (HY-N0292), formed by enzymatic, acidic or acetylated hydrolysis of oleuropein. Dietary intake of oleuropein Aglycone (50 mg/kg diet) increases the number of neuronal autophagic vesicles, reverses cognitive deficits in the TgCRND8 transgenic mouse model of Alzheimer's disease, and reduces the levels of histone deacetylase 2 ( HDAC2 ) in the cortex and hippocampus. Oleuropein Aglycone increases urinary norepinephrine, interscapular brown adipose tissue epinephrine, and UCP1 protein levels, and reduced plasma leptin levels and total abdominal adipose tissue weight in a rat model of high-fat diet-induced obesity. Oleuropein Aglycone also reduced lung neutrophil infiltration, lipid peroxidation, and IL-1β levels in a mouse model of carrageenan-induced pleurisy. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 3,4-DHPEA-EA. CAS No. 31773-95-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-135115. | |
| Oleuropein (Standard) | Oleuropein (Standard) is the analytical standard of Oleuropein. This product is intended for research and analytical applications. Oleuropein, found in olive leaves and oil, exerts antioxidant, anti-inflammatory and anti-atherogenic effects through direct inhibition of PPARγ transcriptional activity [1]. Oleuropein induces apoptosis in breast cancer cells via the p53-dependent pathway and through the regulation of Bax and Bcl2 genes. Oleuropein also inhibits aromatase [2]. Uses: Scientific research. Group: Natural products. CAS No. 32619-42-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0292R. | |
| Oleylamine, 80-90% | Oleylamine, 80-90% (cis-1-Amino-9-octadecene, 80-90%) is a long-chain primary alkylamine, which can be used in nanoparticle synthesis as a solvent, surfactant, and reducing agent. Oleylamine, 80-90% forms metastable complexes with metal ions, which can be controllably decomposed to produce nanoparticles. Oleylamine, 80-90% can control the morphology of nanoparticle, prevent the nanoparticle aggregation, and reduce metal precursors to metal nanoparticles [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: cis-1-Amino-9-octadecene, 80-90%. CAS No. 112-90-3. Pack Sizes: 100 g; 500 g. Product ID: HY-W011696. | |
| Olgotrelvir sodium | Olgotrelvir sodium is an orally active dual inhibitor of coronavirus main protease (Mpro) and human cell cathepsin ( Cathepsin L ). Olgotrelvir sodium can effectively inhibit both SARS-CoV-2 replication and entry into host cells [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: STI-1558 sodium. CAS No. 2763596-72-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-156655A. | |
| Oligomycin | Oligomycin, an antifungal antibiotic, is an inhibitor of H + -ATP-synthase. Oligomycin blocks oxidative phosphorylation and the electron transport chain. Oligomycin inhibits HIF-1alpha expression in hypoxic tumor cells [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 1404-19-9. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-N6782. | |
| Oligomycin A | Oligomycin A (MCH 32), created by Streptomyces , acts as a mitochondrial F 0 F 1 -ATPase inhibitor, with a K i of 1 μM; Oligomycin A shows anti-fungal activity. Uses: Scientific research. Group: Natural products. Alternative Names: MCH 32. CAS No. 579-13-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-16589. | |
| Oligomycin B | Oligomycin B is an antibiotic isolated from marine Streptomyces , used as an eukaryotic ATP synthase inhibitor, induces apoptosis [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 11050-94-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N6784. | |
| Oligopeptide-10 | Oligopeptide-10 is a bioactive peptide with anti-microbial effect and has been reported used as a cosmetic ingredient [1]. Uses: Scientific research. Group: Peptides. CAS No. 466691-40-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P5255. | |
| Olinciguat | Olinciguat (IW-1701) is an oral guanylate cyclase (sGC) stimulator with concentration-dependent stimulation of sGC in purified rat and human enzyme assays and a whole cell assay [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IW-1701. CAS No. 1628732-62-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-109066. | |
| O-Linked GlcNAc transferase substrate | O-Linked GlcNAc transferase substrate is a biological active peptide. (A peptide substrate of O-linked GlcNAc transferase (OGT), a eukaryotic glycosyltransferase that uses UDP-GlcNAc as a glycosyl donor.). Uses: Scientific research. Group: Peptides. CAS No. 954381-93-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P5375. | |
| Olinvacimab | Olinvacimab (TTAC-0001) is a fully human anti-VEGFR2 monoclonal antibody. Olinvacimab inhibits VEGF binds to KDR with a K d value of 0.23 nM. Olinvacimab has antiangiogenic activity. Olinvacimab can be used for the research of recurrent glioblastoma and breast cancer [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: TTAC-0001. CAS No. 2095504-49-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99768. | |
| Olive oil | Cropure OL is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Cropure OL. CAS No. 8001-25-0. Pack Sizes: 50 mL; 100 mL. Product ID: HY-108749. | |
| Olivetol | Olivetol is a naturally phenol found in lichens and produced by certain insects, acting as a competitive inhibitor of the cannabinoid receptors CB1 and CB2 [3]. Olivetol also inhibits CYP2C19 and CYP2D6 activity, with IC 50 s of 15.3 μM, 7.21 μM and K i s of 2.71 μM, 2.87 μM, respectively [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 500-66-3. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-W008364. | |
| Olivetolic acid | Olivetolic acid is a biosynthetic precursor of cannabinol acid (CBGA). Olivetolic acid has anticonvulsant activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 491-72-5. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-W090292. | |
| Olivil | Olivil ((-)-Olivile) is a lignan that has weak DPPH radical-scavenging activity (EC 50 : 176 μM) [1]. Uses: Scientific research. Group: Natural products. Alternative Names: (-)-Olivile; Vladinol C. CAS No. 2955-23-9. Pack Sizes: 1 mg. Product ID: HY-N3141. | |
| Olmesartan | Olmesartan (RNH-6270) is an angiotensin II receptor (AT1R) antagonist used to treat high blood pressure [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RNH-6270. CAS No. 144689-24-7. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-17004. | |
| Olmesartan-d6 | Olmesartan-d 6 (RNH-6270-d 6 ) is the deuterium labeled Olmesartan. Olmesartan (RNH-6270) is an angiotensin II receptor (AT1R) antagonist used to treat high blood pressure[1][2]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: RNH-6270-d6. CAS No. 1185144-74-4. Pack Sizes: 1 mg. Product ID: HY-17004S1. | |
| Olmesartan medoxomil | Olmesartan medoxomil is a potent and selective angiotensin AT1 receptor inhibitor with IC 50 of 66.2 μM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CS 866. CAS No. 144689-63-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-17005. | |
| Olmesartan medoxomil (Standard) | Olmesartan medoxomil (Standard) is the analytical standard of Olmesartan medoxomil. This product is intended for research and analytical applications. Olmesartan medoxomil is a potent and selective angiotensin AT1 receptor inhibitor with IC 50 of 66.2 μM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CS 866 (Standard). CAS No. 144689-63-4. Pack Sizes: 5 mg; 10 mg; 50 mg. Product ID: HY-17005R. | |
| Olmutinib | Olmutinib (HM61713; BI-1482694) is an orally active and irreversible third EGFR tyrosine kinase inhibitor that binds to a cysteine residue near the kinase domain. Olmutinib is used for NSCLC [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HM61713; BI 1482694. CAS No. 1353550-13-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-19730. | |
| Olodaterol | Olodaterol (BI1744) is a selective, long acting β 2 -adrenoceptor (β 2 -AR) agonist ( EC 50 =0.1 nM and pK i = 9.14 for human β 2 -adrenoceptor, respectively). Olodaterol can be used for chronic obstructive pulmonary disease (COPD) and pulmonary fibrosis [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BI1744. CAS No. 868049-49-4. Pack Sizes: 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14301. | |
| Olodaterol hydrochloride | Olodaterol (BI1744) hydrochloride is a selective, long acting β 2 -adrenoceptor (β 2 -AR) agonist ( EC 50 =0.1 nM and pK i = 9.14 for human β 2 -adrenoceptor, respectively). Olodaterol can be used for chronic obstructive pulmonary disease (COPD) and pulmonary fibrosis [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BI1744 hydrochloride. CAS No. 869477-96-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14301A. | |
| Olokizumab | Olokizumab (CDP 6038) is a humanized monoclonal antibody targeting the interleukin-6 (IL-6). Olokizumab can be used in research of rheumatoid arthritis (RA) [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: CDP 6038; OKZ. CAS No. 1007223-17-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99210. | |
| Olopatadine hydrochloride | Olopatadine hydrochloride (ALO4943A) is a histamine blocker used to treat allergic conjunctivitis. Uses: Scientific research. Group: Natural products. Alternative Names: ALO4943A; KW4679. CAS No. 140462-76-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0426A. | |
| Olorofim | Olorofim (F901318) selectively inhibits fungal dihydroorotate dehydrogenase (DHODH) , a key enzyme in the pyrimidine biosynthesis pathway. Olorofim (F901318). Olorofim exhibits excellent activity against A. fumigatus and other Aspergillus spp. [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: F901318. CAS No. 1928707-56-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-104029. | |
| Olpadronic acid | Olpadronic acid (Olpadronate) is an orally active amino-bisphosphonate and inhibits bone resorption. Olpadronic acid also prevents bone destruction and tumor growth in the skeletal prostate cancer mouse model. Olpadronic acid can be used for research of osteoporosis, malignancies and rheumatoid arthritis [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Olpadronate; OLP. CAS No. 63132-39-8. Pack Sizes: 5 mg. Product ID: HY-106431. | |
| Olprinone | Olprinone (Loprinone) is a potent phosphodiesterase (PDE) 3 inhibitor, with IC 50 s of 150, 100, 0.35 and 14 μM for PDE1, PDE2, PDE3 and PDE4, respectively. Olprinone is used for the research of heart failure due to its positive inotropic and vasodilative effects. Anti-inflammatory activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Loprinone. CAS No. 106730-54-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14254A. | |
| Olprinone Hydrochloride | Olprinone (Loprinone) Hydrochloride is a potent phosphodiesterase (PDE) 3 inhibitor, with IC 50 s of 150, 100, 0.35 and 14 μM for PDE1, PDE2, PDE3 and PDE4, respectively. Olprinone Hydrochloride is used for the research of heart failure due to its positive inotropic and vasodilative effects. Anti-inflammatory activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Loprinone Hydrochloride. CAS No. 119615-63-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14254. | |
| Olsalazine | Olsalazine is a potent inhibitor of macrophages chemotaxis to LTB4 with an IC 50 value of 0.39 mM, also reduces the synthesis of 5-hydroxyeicosatetraenoic acid (5-HETE), 11-HETE, 12-HETE, and 15-HETE in polymorphonuclear leukocyte (PMNL) and mononuclear cells (MNL). Olsalazine can be used for researching ulcerative colitis. Anti-inflammatory activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 15722-48-2. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg. Product ID: HY-B0174A. | |
| Oltipraz | Oltipraz has an inhibitory effect on HIF-1α activation in a time-dependent manner, completely abrogating HIF-1α induction at ≥10 μM concentrations, the IC 50 of Oltipraz for HIF-1α inhibition is 10 μM. Oltipraz is a potent Nrf2 activator. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RP 35972; NSC 347901. CAS No. 64224-21-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-12519. | |
| Olumacostat glasaretil | Olumacostat glasaretil (DRM01) is a small molecule inhibitor of acetyl coenzyme A carboxylase ( ACC ). Uses: Scientific research. Group: Signaling pathways. Alternative Names: DRM01. CAS No. 1261491-89-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-17641. | |
| Olutasidenib | Olutasidenib (FT-2102) is a highly potent, orally active, brain penetrant and selective inhibitor of mutant Isocitrate dehydrogenase 1 (IDH1) , with IC 50 values of 21.2 nM and 114 nM for IDH1- R132H and IDH1- R132C, respectively. Olutasidenib (FT-2102) is under the study in the treatment of acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FT-2102. CAS No. 1887014-12-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114226. | |
| Olvanil | Olvanil (NE-19550) is an analgesic and an agonist of transient receptor potential vanilloid type 1 ( TRPV1 ) channels with an EC 50 of 0.7 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NE-19550; N-Vanillyloleamide. CAS No. 58493-49-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101323. | |
| Olverembatinib | Olverembatinib (GZD824) is a potent and orally active pan- Bcr-Abl inhibitor. Olverembatinib potently inhibits a broad spectrum of Bcr-Abl mutants. Olverembatinib strongly inhibits native Bcr-Abl and Bcr-Abl T315I with IC 50 s of 0.34 nM and 0.68 nM, respectively. Olverembatinib has antitumor activity [1]. Olverembatinib is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GZD824; HQP1351. CAS No. 1257628-77-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15666. | |
| Omaciclovir | Omaciclovir (H2G) is a potent and selective inhibitor of herpesvirus replication. Omaciclovir is a nucleoside analog with antiviral activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: H2G. CAS No. 124265-89-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116174. | |
| Omadacycline | Omadacycline (PTK 0796), a first-in-class orally active aminomethylcycline antibacterial , is a member of the tetracycline class of antibiotics. Omadacycline acts through the inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PTK 0796; Amadacycline. CAS No. 389139-89-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-14865. | |
| Omadacycline hydrochloride | Omadacycline (PTK 0796) hydrochloride, a first-in-class orally active aminomethylcycline antibacterial , is a member of the tetracycline class of antibiotics. Omadacycline hydrochloride acts through the inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline hydrochloride possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline hydrochloride can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PTK0796 hydrochloride; Amadacycline hydrochloride. CAS No. 1196800-39-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-14865C. | |
| Omadacycline tosylate | Omadacycline (PTK 0796) tosylate, a first-in-class orally active aminomethylcycline antibacterial , is a member of the tetracycline class of antibiotics. Omadacycline tosylate acts through the inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline tosylate possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline tosylate can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PTK 0796 tosylate; Amadacycline tosylate. CAS No. 1075240-43-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14865B. | |
| Omalizumab | Omalizumab is a recombinant, humanized, monoclonal antibody against human immunoglobulin E (IgE) with a K D of 0.393 nM. Omalizumab binds to the human FcγRIIb receptors with a K D of 6.37 uM. Omalizumab has the potential for persistent allergic asthma research [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Olizumab; rhuMab-E25. CAS No. 242138-07-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P9950. | |
| Omapatrilat | Omapatrilat is a dual inhibitor of the metalloproteases ACE and NEP with K i values of 0.64 and 0.45 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-186716. CAS No. 167305-00-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18208. | |
| Omarigliptin | Omarigliptin (MK-3102) is a potent, selective, orally active and cross the blood-brain barrier dipeptidyl peptidase 4 (DPP-4) inhibitor. Omarigliptin shows anti-parkinsonian activity. Omarigliptin has the neuroprotective effect to improve diabetes-associated cognitive dysfunction [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-3102. CAS No. 1226781-44-7. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15981. | |
| Omaveloxolone | Omaveloxolone (RTA 408) is an antioxidant inflammation modulator (AIM), which activates Nrf2 and suppresses nitric oxide (NO). Omaveloxolone attenuates osteoclastogenesis by inhibiting STING dependent NF-κb signaling. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RTA 408. CAS No. 1474034-05-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12212. | |
| Ombitasvir | Ombitasvir is a potent inhibitor of the hepatitis C virus protein NS5A , with EC 50 s of 0.82 to 19.3 pM against HCV genotypes 1 to 5, and 366 pM against genotype 6a. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABT-267. CAS No. 1258226-87-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13997. | |
| Ombrabulin | Ombrabulin (AVE8062) is a derivative of CA-4 phosphate, which is known to exhibit antivascular effects through selective disruption of the tubulin cytoskeleton of endothelial cells. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AVE8062; AC7700. CAS No. 181816-48-8. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-14797. | |
| Ombrabulin hydrochloride | Ombrabulin hydrochloride is a derivative of CA-4 phosphate, which is known to exhibit antivascular effects through selective disruption of the tubulin cytoskeleton of endothelial cells. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AVE8062 hydrochloride; AC7700 hydrochloride. CAS No. 253426-24-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18256. | |
| Omburtamab | Omburtamab is an anti-CD276 (also known as B7-H3 ) monoclonal antibody, CD276 is a B7/CD28 immunoglobulin superfamily member expressed among solid human tumours. Omburtamab can bind tumor tissues and be used in various cancers research [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1895083-75-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99157. | |
| Omecamtiv mecarbil | Omecamtiv mecarbil (CK-1827452) is a selective cardiac myosin activator. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CK-1827452. CAS No. 873697-71-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14233. | |
| ω-Muricholic Acid | ω-Muricholic acid (ω-MCA) is a murine-specific secondary bile acid [1]. Uses: Scientific research. Group: Natural products. CAS No. 6830-3-1. Pack Sizes: 1 mg. Product ID: HY-125138. | |
| ω-Pentadecalactone | ω-Pentadecalactone is a fragrance ingredient. ω-Pentadecalactone is a member of the fragrance structural group macrocyclic lactone and lactide derivative [1]. Uses: Scientific research. Group: Natural products. CAS No. 106-02-5. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-W035362. | |
| Omeprazole | Omeprazole (H 16868), a proton pump inhibitor (PPI), is available for treatment of acid-related gastrointestinal disorders. Omeprazole shows competitive inhibition of CYP2C19 activity with a K i of 2 to 6 μM [1]. Omeprazole also inhibits growth of Gram-positive and Gram-negative bacteria [2].Omeprazole is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor) [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: H 16868. CAS No. 73590-58-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-B0113. | |
| Omeprazole sodium | Omeprazole sodium (H 16868 sodium), a proton pump inhibitor (PPI), is available for treatment of acid-related gastrointestinal disorders. Omeprazole sodium shows competitive inhibition of CYP2C19 activity with a K i of 2 to 6 μM [1]. Omeprazole sodium also inhibits growth of Gram-positive and Gram-negative bacteria [2]. Omeprazole is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor) [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: H 16868 sodium. CAS No. 95510-70-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0113A. | |
| Omeprazole (Standard) | Omeprazole (Standard) is the analytical standard of Omeprazole. This product is intended for research and analytical applications. Omeprazole (H 16868), a proton pump inhibitor (PPI), is available for treatment of acid-related gastrointestinal disorders. Omeprazole shows competitive inhibition of CYP2C19 activity with a K i of 2 to 6 μM [1]. Omeprazole also inhibits growth of Gram-positive and Gram-negative bacteria [2].Omeprazole is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor) [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 73590-58-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0113R. | |
| Omeprazole sulfone | Omeprazole sulfone is a metabolite of Omeprazole, which is a proton pump inhibitor. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Omeprazole sulphone. CAS No. 88546-55-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-G0007. | |
| O-Methylsterigmatocystin | O-Methylsterigmatocystin is a metabolite in Aspergillus flavus and Aspergillus parasiticus [1]. Uses: Scientific research. Group: Natural products. CAS No. 17878-69-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-116909. | |
| Omidenepag | Omidenepag (UR-7276), a pharmacologically active form of Omidenepag Isopropyl, is a selective, non-prostanoid EP2 receptor agonist, with an EC 50 of 1.1 nM. Omidenepag shows binding affinities (IC 50 ) 10 nM for h-EP2 [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: UR-7276. CAS No. 1187451-41-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17642. | |
| Omidenepag isopropyl | Omidenepag isopropyl is a selective EP2 receptor agonist. Omidenepag isopropyl is converted to the active product Omidenepag during corneal penetration, and Omidenepag is a highly selective EP2 receptor agonist. Omidenepag isopropyl shows only weak affinity for EP1, EP2, and FP receptors. Omidenepag isopropyl is under development for the treatment of glaucoma as an intraocular pressure (IOP)-lowering agent. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DE-117. CAS No. 1187451-19-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111406. | |
| Omiganan | Omiganan is a cationic antimicrobial peptide. Omiganan as an analogue of indolicidin shows activity against gram-positive and gram-negative bacteria but also Candida spp. isolates. Omiganan can be used for the research of alcohol nose and acne [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 204248-78-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-105048. | |
| Omigapil maleate | Omigapil maleate, an orally bioavailable GAPDH nitrosylation inhibitor, abrogates Aβ 1-42 -induced tau acetylation, memory impairment, and locomotor dysfunction in mice. Omigapil maleate has the potential for the research of Alzheimer's disease [1]. Omigapil maleate (CGP3446B maleate) is a apoptosis inhibitor. Omigapil maleate can be used for the research of congenital muscular dystrophy (CMD) [2]. Omigapil (maleate) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CGP3466B; CGP3446 maleate; TCH346 maleate. CAS No. 200189-97-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16361A. | |
| Omilancor | BT-11 is an orally available LANCL2 binding compound for treating inflammatory bowel disease. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BT-11. CAS No. 1912399-75-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-102013. | |
| Ompenaclid | Ompenaclid (RGX-202) is an oral small-molecule SLC6A8 transporter inhibitor. Ompenaclid robustly inhibits creatine import in vitro and in vivo, reduces intracellular phosphocreatine and ATP levels, and induces tumor apoptosis. Ompenaclid can be used for the research of cancer and duchenne muscular dystrophy [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: RGX-202; 3-Guanidinopropionic acid. CAS No. 353-09-3. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-W015828. | |
| Omtriptolide | Omtriptolide (PG490-88) is a derivative proagent of triptolide purified from the Chinese herb. Uses: Scientific research. Group: Signaling pathways. CAS No. 195883-06-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-16363. | |
| Onalespib | Onalespib (AT13387) is a long-acting second-generation Hsp90 inhibitor with a K d of 0.71 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AT13387. CAS No. 912999-49-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14463. | |
| Onartuzumab | Onartuzumab (MetMAb) is a unique, humanized and affinity-matured monovalent (one-armed) monoclonal antibody against the MET receptor. Onartuzumab potently inhibits HGF binding and receptor phosphorylation and signaling. Onartuzumab has antibody-like pharmacokinetics and antitumor activity [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MetMAb. CAS No. 1133766-06-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99250. | |
| ONC212 | ONC212, a fluorinated-ONC201 analogue, is a promising anti-cancer agent and also a selective agonist of GPR132. ONC212 also induces apoptosis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1807861-48-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111343. | |
| ONC213 | ONC213 is an αKGDH inhibitor that suppresses mitochondrial respiration and elevates α-ketoglutarate levels by inhibiting αKGDH activity, leading to apoptosis ( Apoptosis ) in AML cells. ONC213 can be used in acute myeloid leukemia research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1977540-13-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-164515. | |
| Oncaspar | Oncaspar (PEG-L-asparaginase; Pegasparaginase), a pegylated form of native Escherichia coli -derived L-asparaginase, breaks down the amino acid asparagine that are circulating in the bloodstream. Oncaspar plays an important role in acute lymphoblastic leukemia (ALL) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PEG-L-asparaginase; Pegasparaginase. CAS No. 130167-69-0. Pack Sizes: 5 mL. Product ID: HY-108860. | |
| Oncrasin-1 | Oncrasin-1 is a potent and effective anticancer inhibitor that kills various human lung cancer cells with K-Ras mutations at low or submicromolar concentrations; also led to abnormal aggregation of PKCΙ in nucleus of sensitive cells but not in resistant cells. Uses: Scientific research. Group: Signaling pathways. CAS No. 75629-57-1. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16662. | |
| Oncrasin-60 | Oncrasin-60 (NSC-741909) is a compound with antitumor activity that is active against multiple cancer cell lines in vitro and can induce tumor regression in vivo, with its mechanism involving JNK activation and STAT3 inhibition. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NSC-741909. CAS No. 92407-91-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122315. | |
| Ondansetron | Ondansetron (GR 38032; SN 307) is a highly selective 5-HT 3 receptor antagonist, with IC 50 value of 103 pM. Ondansetron exerts antiemetic effects by antagonizing 5-HT receptor located on local neurons in the peripheral and central nervous system. Ondansetron suppresses nausea and vomiting caused by chemotherapy and radiation therapy. Ondansetron has orally bioactivity [1] [2] [3] [4] [5] [6] [7] [8]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GR 38032; SN 307. CAS No. 99614-02-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0002B. | |
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