MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| N-trans-Feruloyltyramine | N-trans-Feruloyltyramine (N-feruloyltyramine), an alkaloid, is a potent antioxidant. N-trans-Feruloyltyramine improves H 2 O 2 -induced intracellular ROS generation and decreases apoptosis. N-trans-Feruloyltyramine has the potential for oxidative stress-related neurodegenerative conditions and cancer research [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: N-feruloyltyramine; Moupinamide. CAS No. 66648-43-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N2410. |  |
| NTRC-824 | NTRC-824 (Compound 5) is a potent, selective and neurotensin-like nonpeptide neurotensin receptor type 2 (NTS2) antagonist with an IC 50 of 38 nM and a K i of 202 nM. NTRC-824 is >150-fold selectivity for NTS2 over NTS1 (K i >30 μM) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1623002-61-8. Pack Sizes: 1 mg. Product ID: HY-12436. | |
| NUC-7738 | NUC-7738, an aryloxy phosphoramidate of 3-Deoxyadenosine, is a 5-aryloxy phosphoramidate prodrug of 3-Deoxyadenosine (3-dA). NUC-7738 has potent cytotoxic activity against a panel of hematological cancer cell lines. NUC-7738 can be used in research of cancer [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2348493-39-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-136506. | |
| Nuciferine | Nuciferine is an antagonist at 5-HT 2A ( IC 50 =478 nM), 5-HT 2C ( IC 50 =131 nM), and 5-HT 2B ( IC 50 =1 μM), an inverse agonist at 5-HT 7 ( IC 50 =150 nM), a partial agonist at D 2 ( EC 50 =64 nM), D 5 ( EC 50 =2.6 μM) and 5-HT 6 ( EC 50 =700 nM), an agonist at 5-HT 1A ( EC 50 =3.2 μM) and D 4 ( EC 50 =2 μM) receptor. Uses: Scientific research. Group: Natural products. CAS No. 475-83-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-N0049. | |
| Nuclear Fast Red | Nuclear Fast Red, an anthraquinone dye, is commonly used in conjunction with an excess of aluminum ions as a red nuclear counterstain. Nuclear fast red has been used as a histochemical and colorimetric reagent for calcium [1]. Nuclear fast red as highly sensitive "off/on" fluorescent probe for detecting guanine [2]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Kernechtrot. CAS No. 6409-77-4. Pack Sizes: 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-D0943. | |
| Nuclease P1 | Nuclease P1 is a single-stranded specific endonuclease, it hydrolyzes nucleic acids into 5'-mononucleotides and cleaves the single-stranded region of a double-stranded nucleic acid. Nuclease P1 is one of the most well-known single stranded specific nucleases in the field of molecular biology, it is widely used in the pharmaceutical and food industries [1]. Nuclease P1 can be obtained by fermentation of Penicillium citrinum: through extraction process, ultrafiltration concentration, drying and purification, etc. Uses: Scientific research. Group: Signaling pathways. CAS No. 54576-84-0. Pack Sizes: 250 U. Product ID: HY-P2963. | |
| Nuclease S1, Aspergillus oryzae | Nuclease S1, Aspergillus oryzae is a specific endonuclease that degrades single stranded DNA (ssDNA) and RNA. Nuclease S1 can also remove protruding single-strand ends from double-stranded DNA [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 37288-25-8. Pack Sizes: 10 KU. Product ID: HY-P2773. | |
| Nuclease, Serratia marcescens | Serratia marcescens nuclease (EC 3.1.30.2) is a nonspecific nuclease. Serratia marcescens nuclease has broad utility due to its potent digestive activity toward both DNA and RNA [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Serratia marcescens nuclease. CAS No. 9025-65-4. Pack Sizes: 5 KU; 10 KU; 25 KU. Product ID: HY-131160. | |
| Nucleoprotein (396-404) | Nucleoprotein (396-404) is the 396 to 404 fragment of lymphocytic choriomeningitis virus (LCMV). Nucleoprotein (396-404) is the H-2D(b)-restricted immunodominant epitope and can be used as a molecular model of viral antigen [1] [2]. Uses: Scientific research. Group: Peptides. Alternative Names: NP 396. CAS No. 158475-79-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1571. | |
| Nudifloramide | Nudifloramide (2PY) is one of the end products of nicotinamide-adenine dinucleotide (NAD) degradation. Nudifloramide significantly inhibits poly(ADP-ribose) polymerase (PARP-1) activity in vitro [1]. Uses: Scientific research. Group: Natural products. Alternative Names: 2PY. CAS No. 701-44-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113432. | |
| Numidargistat | Numidargistat (CB-1158) is a potent and orally active inhibitor of arginase , with IC 50 s of 86 nM and 296 nM for recombinant human arginase 1 and recombinant human arginase 2 , respectively. Immuno-oncology agent [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CB-1158; INCB01158. CAS No. 2095732-06-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-101979. | |
| Nurr1 agonist 4 | Nurr1 agonist 4 (compound 8) is a high-affinity Nurr1 agonist with EC 50 of 2.1 μM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 87645-58-7. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-149867. | |
| Nurr1 agonist 7 | Nurr1 agonist 7 (compound 110) is a Nurr1 agonist with an EC 50 value of 0.12 μM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 228707-95-7. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-157026. | |
| Nurr1 inverse agonist-1 | Nurr1 inverse agonist-1 is an inverse agonist tool for the neuroprotective transcription factor Nurr1. Uses: Scientific research. Group: Signaling pathways. CAS No. 2758673-07-1. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-132909. | |
| Nurulimab | Nurulimab (BCD-145) is an anti- cytotoxic T lymphocyte antigen-4 (anti-CTLA-4) human monoclonal antibody. Nurulimab can be can be used in research of melanoma [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BCD-145. CAS No. 2168561-20-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99760. | |
| Nutlin-3 | Nutlin-3 is a commercial available p53-MDM2 inhibitor, with K i of 90 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 548472-68-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-50696. | |
| Nutlin-3a | Nutlin-3a (Rebemadlin), an active enantiomer of Nutlin-3, is a potent murine double minute (MDM2) inhibitor ( IC 50 =90 nM). Nutlin-3a inhibits MDM2-p53 interactions and stabilizes the p53 protein, and induces cell autophagy and apoptosis. Nutlin-3a has the potential for the study of TP53 wild-type ovarian carcinomas [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Rebemadlin. CAS No. 675576-98-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10029. | |
| NV03 | NV03 is a potent and selective antagonist of UHRF1 (Ubiquitin-like with PHD and RING finger domains 1)- H3K9me3 interaction by binding to UHRF1 tandem tudor domain, with a K d of 2.4 μM. NV03 has anticancer activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2448341-58-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125292. | |
| NV-5138 | NV-5138, a leucine analog, is the first selective and orally active brain mTORC1 activator, binding to Sestrin2. NV-5138 is used for antidepressant studies [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2095886-80-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114384. | |
| NV-5138 hydrochloride | NV-5138 hydrochloride, a leucine analog, is the first selective and orally active brain mTORC1 activator, binding to Sestrin2. NV-5138 hydrochloride is used for antidepressant studies [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2639392-70-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-114384B. | |
| N-Vanillyldecanamide | N-Vanillyldecanamide, a capsaicinoid isolated from the fruits of Capsicum annuum , significantly reduced the radical length of Lactuca sativa seedling in a dose-dependent manner [1]. Uses: Scientific research. Group: Natural products. CAS No. 31078-36-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N5099. | |
| NVP-CGM097 | NVP-CGM097 is a potent and selective MDM2 inhibitor with IC 50 of 1.7±0.1 nM for hMDM2. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CGM097. CAS No. 1313363-54-0. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15954. | |
| NVP-CGM097 sulfate | NVP-CGM097 sulfate is a potent and selective MDM2 inhibitor with IC 50 of 1.7±0.1 nM for hMDM2. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CGM097 sulfate. CAS No. 1313367-56-4. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15954B. | |
| NVP-DFF332 | HIF-2α-IN-8 is a potent and orally active HIF2α inhibitor with IC 50 values of 9, 37, 246 nM for HIF2α SPA, HIF2α iScript, HIF2α HRE RGA, respectively. HIF-2α-IN-8 shows antitumor activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HIF-2α-IN-8. CAS No. 2734922-78-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-148860. | |
| NVP-TNKS656 | NVP-TNKS656 is a highly potent, selective, and orally active TNKS2 inhibitor with IC 50 of 6 nM, and is > 300 fold selectivity against PARP1 and PARP2. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TNKS656. CAS No. 1419949-20-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13990. | |
| NVS-CECR2-1 | NVS-CECR2-1, a non-BET family Bromodomain (BRD) inhibitor, is a potent and selective cat eye syndrome chromosome region, candidate 2 ( CECR2 ) inhibitor. NVS-CECR2-1 binds to CECR2 BRD with high affinity ( IC 50 =47 nM; K D =80 nM). NVS-CECR2-1 exhibits cytotoxic activity and induces apoptosis against various cancer cells by targeting CECR2 as well as via CECR2-independent mechanism [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1992047-61-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110374. | |
| NVS-PAK1-1 | NVS-PAK1-1 is a potent and selective allosteric PAK1 inhibitor with an IC 50 of 5 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1783816-74-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100519. | |
| NVS-PAK1-C | NVS-PAK1-C is a potent, ATP-competitive and specific allosteric PAK1 inhibitor probe with IC 50 values of 5 nM and 6 nM for dephosphorylated PAK1 and phosphorylated PAK1, respectively. NVS-PAK1-C is also against dephosphorylated PAK2 ( IC 50 =270 nM) and phosphorylated PAK2 ( IC 50 =720 nM) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2250019-95-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-131043. | |
| NX-1607 | NX-1607 (Compound 23) is an inhibitor of Cbl-b , an E3 enzyme in the ubiquitin-proteasome pathway, with an IC 50 value of less than 1 nM. NX-1607 can be used in cancer research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Cbl-b-IN-3. CAS No. 2573775-59-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141432. | |
| NX-2127 | NX-2127 (compound 28) is an orally active PROTAC deggrader, targeting to Brutons Tyrosine Kinase (Btk). NX-2127 inhibits proliferation of BTK C481S mutant TMD8 cells, more effectively than Ibrutinib (HY-10997). NX-2127 catalyzes the degradation of Ikaros (IKZF1) and Aiolos (IKZF3) with of 25 nM and 54 nM, respectively. NX-2127 stimulates T cell activation and increases IL-2 production in primary human T Cells [1] [2]. NX-2127 is composed of PROTAC target protein ligand (red part) BTK ligand 10 (HY-168302), E3 ligase ligand (blue part) Thalidomide 5-fluoride (HY-W087383) and PROTAC Linker (black part) (S)-4-(1-(Pyrrolidin-3-ylmethyl)piperidin-4-yl)aniline (HY-168303). Among which, the conjugate of E3 ubiquitin ligase ligand + Linker compose of Thalidomide-pyrrolidine-C-piperidine-Ph-NH2 (HY-168304). Uses: Scientific research. Group: Signaling pathways. CAS No. 2416131-46-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153220. | |
| NX-5948 | NX-5948 (BTK-IN-24) is an orally active chimeric targeting molecule (CTM) that induces specific BTK protein degradation by the cereblon E3 ligase (CRBN) complex without degradation of other cereblon neo-substrates. NX-5948 mediates potent anti-inflammatory activity via BTK degradation with resultant inhibition of B cell activation. NX-5948 exhibits potent tumor growth inhibition in TMD8 xenograft models that contain either wild-type BTK or BTKi-resistant mutations. NX-5948 is efficacious in a mouse collageninduced arthritis (CIA) model. NX-5948 can cross the blood brain barrier (BBB). NX-5948 is a PROTAC composed of the ligand for target protein, a linker, and a cereblon E3 ligase (CRBN) complex (Red: ligand for target protein; Blue: CRBN; Black: linker) [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BTK-IN-24. CAS No. 2649400-34-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-153321. | |
| NXP800 | NXP800 (CCT361814) is a potent and orally active heat shock factor 1 (HSF1) pathway inhibitor. NXP800 has the potential for cancer research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CCT361814. CAS No. 1693734-80-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145927. | |
| Nybomycin | Nybomycin, an antibiotic, exhibits antiphage and antibacterial properties. Nybomycin binds to DNA and induces a unique morphological change to mycobacterial bacilli leading the bacterial cell death [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 30408-30-1. Pack Sizes: 500 μg. Product ID: HY-123635. | |
| NY-ESO-1 (157-165) peptide | NY-ESO-1 (157-165) peptide is a peptide fragment from NY-ESO-1 protein. NY-ESO-1 (157-165) peptide can activate the immune system, especially for HLA-A2 positive individuals, it can be recognized by CD8+ T cells, thus triggering an immune response. NY-ESO-1 (157-165) peptide is expressed in a variety of tumors and can be used as a target for tumor immunotherapy [1]. Uses: Scientific research. Group: Peptides. CAS No. 202815-17-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P10493. | |
| Nylidrin hydrochloride | Nylidrin hydrochloride is an inhibitor of IgE-mediated histamine release in passive sensitized rat peritoneal mast cells, and it has anti-allergic effects. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Buphenine hydrochloride. CAS No. 849-55-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg. Product ID: HY-B1404. | |
| Nystatin | Nystatin is an orally active polyene antifungal antibiotic effective against yeast and mycoplasma. Nystatin increases the permeability of plasma membranes to small monovalent ions, including chloridion [1] [2]. Nystatin is a cholesterol-sequestering agent [3] , partially prevents Oxaliplatin-induced lipid raft aggregation, DR4 and DR5 clustering, and thereby reduces apoptosis [5]. Uses: Scientific research. Group: Natural products. CAS No. 1400-61-9. Pack Sizes: 500 mg. Product ID: HY-17409. | |
| NYX-2925 | NYX-2925 is an orally active NMDAR modulator. NYX-2925 restores levels of activated Src and Src phosphorylation sites on GluN2A and GluN2B in the mPFC. NYX-2925 shows no effect on CAMKII, and any addictive or sedative/ataxic side effects. NYX-2925 can be used for research of a variety of NMDA receptor-mediated central nervous system disorders [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2012536-16-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135741. | |
| O-1602 | O-1602 is an agonist of GPR55 (G protein-coupled receptor 55). O-1602 reduces the number and activation of hippocampal microglia induced by METH (methamphetamine). O-1602 decreases the expression levels of NLRP3 inflammasome proteins, including NLRP3, ASC and Caspase-1 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 317321-41-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107541. | |
| O6-Benzylguanine | O6-Benzylguanine, a guanine analog, is the DNA repair enzyme O6-alkylguanine-DNA alkyltransferase (MGMT/AGT) inhibitor. O6-Benzylguanine acts as an AGT substrate, which transfers its benzyl group to the AGT cysteine residue, thereby irreversibly inactivating AGT and preventing DNA repair. O6-Benzylguanine induces tumor cell apoptosis. Antineoplastic activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 19916-73-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W002585. | |
| O-Acetylserine | O-Acetylserine (O-Acetyl-L-serine) is an intermediate in the biosynthesis of the amino acid cysteine in bacteria and plants. Uses: Scientific research. Group: Natural products. Alternative Names: O-Acetyl-L-serine. CAS No. 5147-00-2. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-101409. | |
| OARV-771 | OARV-771 is a VHL-based BET degrader (PROTAC) with improved cell permeability. OARV-771 shows DC 50 s of 6, 1, and 4 nM for Brd4, Brd2 and Brd3, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2683008-37-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145264. | |
| OB-1 | OB-1 is a stomatin-like protein-3 ( STOML3 ) oligomerization blocker. OB-1 is an effective inhibitor of the self-association of Stomatin , STOML1 and STOML2 , but not podocin [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 300803-69-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122671. | |
| Obatoclax Mesylate | Obatoclax Mesylate (GX15-070 Mesylate), a BH3 mimetic, is a pan- BCL-2 family proteins inhibitor with a K i of 220 nM for BCL-2 [1] [2]. Obatoclax Mesylate induces autophagy -dependent cell death and targets cyclin D1 for proteasomal degradation. Obatoclax Mesylate has anti-cancer and broad-spectrum antiparasitic activity [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GX15-070 Mesylate. CAS No. 803712-79-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10969. | |
| Obefazimod | Obefazimod (ABX464) is a potent anti-HIV agent. Obefazimod inhibits HIV-1 replication in stimulated peripheral blood mononuclear cells (PBMCs) with an IC 50 ranging between 0.1 μM and 0.5 μM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABX464. CAS No. 1258453-75-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100870. | |
| Obeldesivir | Obeldesivir (ATV006) is a potent, orally active antiviral agent and ester proagents of GS-441524. Obeldesivir inhibits the replication of SARS-CoV-2 and its variants. Obeldesivir can be used for SARS-CoV-2 research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ATV006. CAS No. 2647441-36-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145994. | |
| O-Benzylhydroxylamine hydrochloride | O-Benzylhydroxylamine hydrochloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 2687-43-6. Pack Sizes: 100 g. Product ID: HY-41915. | |
| Obeticholic acid | Obeticholic acid (INT-747) is a potent, selective and orally active FXR agonist with an EC 50 of 99 nM. Obeticholic acid has anticholeretic and anti-inflammation effect. Obeticholic acid also induces autophagy [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: INT-747; 6-ECDCA; 6-Ethylchenodeoxycholic acid. CAS No. 459789-99-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-12222. | |
| Obexelimab | Obexelimab (XmAb5871) is a humanized anti- CD19 antibody. Obexelimab works by inhibiting B cell receptor (BCR) mediated calcium influx and promoting the phosphorylation of Fc γ receptor IIb (FcγRIIb), which reduces B cell activation and function, leading to B cell apoptosis. Obexelimab can be used in research for rheumatoid arthritis and systemic lupus erythematosus [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: XmAb5871. CAS No. 1690307-05-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99761. | |
| OBI-3424 | OBI-3424 (TH-3424) is a proagent that is selectively converted by AKR1C3 (aldo-keto reductase 1C3) to a potent DNA-alkylating agent. OBI-3424 can be used for hepatocellular carcinoma, castrate-resistant prostate cancer, and acute lymphoblastic leukemia (ALL) research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TH-3424. CAS No. 2097713-68-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124573. | |
| Obicetrapib | TA-8995 is a new and selective cholesteryl ester transfer protein (CETP) inhibitor. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TA-8995; DEZ-001. CAS No. 866399-87-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-18778. | |
| Obiltoxaximab | Obiltoxaximab (ETI 204) is the second and potent anti-protective antigen (PA) monoclonal antibody with immunogenicity. Obiltoxaximab plays a central role in anthrax toxin assembly and target cell intoxication, promoting survival, and inhibiting bacterial spread to the periphery in animal models. Obiltoxaximab can be used in the research of inhalational anthrax, bacteremia and toxemia [1] [2] [3] [4]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ETI 204. CAS No. 1351337-07-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9932. | |
| Obinutuzumab | Obinutuzumab (GA101) a Type II CD20 humanized IgG1 monoclonal antibody in development for non-Hodgkin lymphoma. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: GA101; Anti-Human CD20 type II, Humanized Antibody. CAS No. 949142-50-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9910. | |
| Obtusifolin | Obtusifolin, isolated from the seeds of Cassia obtusifolia , regulates the gene expression and production of MUC5AC mucin in airway epithelial cells via inhibiting NF-kB pathway [1]. Obtusifolin suppresses phthalate esters-induced breast cancer bone metastasis by targeting parathyroid hormone-related protein [2]. Uses: Scientific research. Group: Natural products. CAS No. 477-85-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg. Product ID: HY-N2098. | |
| Obtusin | Obtusin, isolated from Cassia obtusifolia Linn seed, is a highly selective and competitive human monoamine oxidase-A (hMAO-A) inhibitor with an IC 50 of 11.12 μM and a K i of 6.15 μM. Obtusin plays a preventive role in neurodegenerative diseases, especially anxiety and depression [1]. Uses: Scientific research. Group: Natural products. CAS No. 70588-05-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N6057. | |
| Ocadusertib | Ocadusertib is a potent Serine/Threonine kinase receptor-interacting protein kinase 1 (RIPK1) inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY3871801; R 552. CAS No. 2382811-41-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148297. | |
| Ocaratuzumab | Ocaratuzumab (AME 133v) is an Fc-engineered humanized IgG1 anti- CD20 monoclonal antibody, with a K d of ~100 pM. Ocaratuzumab exhibits more effective antibody-dependent cell-mediated cytotoxicity (ADCC) [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: AME 133v; LY 2469298; Humanized Anti-MS4A1 Recombinant Antibody. CAS No. 1169956-08-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99308. | |
| Ocedurenone | Ocedurenone is a corticosteroid receptor antagonist. Ocedurenone can be used for the research of kidney disease (WO2018054357, compound I) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KBP-5074. CAS No. 1359969-24-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132827. | |
| Ochratoxin C | Ochratoxin C is the ethyl ester analog of ochratoxin A, a mycotoxin produced by A. ochraceus , A. carbonarius , and P. verrucosum that is commonly found as a food contaminant. Uses: Scientific research. Group: Natural products. CAS No. 4865-85-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-125699. | |
| Ocinaplon | Ocinaplon (DOV 273547) is a partial GABAA receptor positive allosteric modulator with relatively high efficacy at the α1 subunit [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DOV 273547. CAS No. 96604-21-6. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-W001692. | |
| Ociperlimab | Ociperlimab is a humanized IgG1 anti- TIGIT antibody. Ociperlimab binds to the extracellular domain of human TIGIT with high affinity ( K D = 0.135 nM). Ociperlimab blocks the interaction between TIGIT and its ligands PVR or PVR-L2. Ociperlimab can be used in research of cancer [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BGB-A1217. CAS No. 2342597-93-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99763. | |
| Oclacitinib | Oclacitinib is a novel JAK inhibitor. Oclacitinib is most potent at inhibiting JAK1 ( IC 50 =10 nM). Uses: Scientific research. Group: Signaling pathways. Alternative Names: PF-03394197. CAS No. 1208319-26-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13577. | |
| Ocrelizumab | Ocrelizumab (Ocrevus) is a humanized anti- CD20 monoclonal antibody. Ocrelizumab can induce B cell depletion and inhibit multiple sclerosis lesions in mice through antibody dependent cytotoxicity (ADCC) [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 637334-45-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9960. | |
| o-Cresolphthalein complexone | o-Cresolphthalein complexone is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells. Uses: Scientific research. Group: Fluorescent dye. CAS No. 2411-89-4. Pack Sizes: 1 g; 5 g; 10 g. Product ID: HY-D0250. | |
| Oct-1-en-3-ol | Oct-1-en-3-ol, a fatty acid fragrant, is a self-stimulating oxylipin messenger. Oct-1-en-3-ol serves as a signaling molecule in plant cellular responses, plant-herbivore interactions, and plant-plant interactions. Oct-1-en-3-ol causes dopamine neuron degeneration through disruption of dopamine handling [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 3391-86-4. Pack Sizes: 10 mM * 1 mL; 10 g; 25 g. Product ID: HY-W010410. | |
| Octacosane-d58 | Octacosane-d 58 is the deuterium labeled Octacosane[1]. Octacosane is an endogenous metabolite with antibacterial activity. Octacosane shows high cytotoxicity against murine melanoma B16F10-Nex2 cells besides inducing protection against a grafted subcutaneous melanoma. Octacosane has the larvicidal activity against mosquito Culex quinquefasciatus with the LC50 concentration of 7.2 mg/l[2][3][4]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: n-Octacosane-d58; NSC 5549-d58. CAS No. 16416-33-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-W272217S. | |
| Octacosanoic acid | Octacosanoic acid is a very long-chain saturated fatty acid. It is the major component of D-003, a mixture of very long-chain aliphatic acids purified from sugar cane wax that has antiplatelet and cholesterol-lowering activities in animal models [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Montanic acid. CAS No. 506-48-9. Pack Sizes: 25 mg; 50 mg. Product ID: HY-N8425. | |
| Octadecanal | Octadecanal is a long-chain aldehyde, present in both thigh and breast muscle [1]. Uses: Scientific research. Group: Natural products. CAS No. 638-66-4. Pack Sizes: 50 mg; 100 mg. Product ID: HY-W004307. | |
| Octadecane | Octadecane is an alkane that is used to store thermal energy at ambient temperature as a phase change material [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 593-45-3. Pack Sizes: 1 g. Product ID: HY-N6600. | |
| Octadecanedioic acid | Octadecanedioic acid, an endogenous metabolite, is a long-chain dicarboxylic acid that has been found in serum free fatty acid profile in Reye syndrome [1]. Uses: Scientific research. Group: Natural products. CAS No. 871-70-5. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-W005178. | |
| Octaethylene glycol | Octaethylene glycol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 5117-19-1. Pack Sizes: 100 mg; 500 mg; 1 g; 5 g; 10 g; 25 g; 100 g. Product ID: HY-W050087. | |
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