MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Lidocaine hydrochloride | Lidocaine hydrochloride (Lignocaine hydrochloride) inhibits sodium channels involving complex voltage and using dependence [1]. Lidocaine hydrochloride decreases growth, migration and invasion of gastric carcinoma cells via up-regulating miR-145 expression and further inactivation of MEK/ERK and NF-κB signaling pathways. Lidocaine hydrochloride is an amide derivative and a agent to treat ventricular arrhythmia and an effective tumor-inhibitor [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Lignocaine hydrochloride. CAS No. 73-78-9. Pack Sizes: 10 mM * 1 mL; 500 mg; 5 g; 10 g. Product ID: HY-B0185A. |  |
| Lidocaine hydrochloride hydrate | Lidocaine (Lignocaine) hydrochloride hydrate inhibits sodium channels involving complex voltage and using dependence. Lidocaine hydrochloride hydrate decreases growth, migration and invasion of gastric carcinoma cells via up-regulating miR-145 expression and further inactivation of MEK/ERK and NF-κB signaling pathways. Lidocaine hydrochloride hydrate is an amide derivative and has potential for the research of ventricular arrhythmia [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Lignocaine hydrochloride hydrate. CAS No. 6108-05-0. Pack Sizes: 50 mg; 100 mg. Product ID: HY-B0185B. | |
| Lidoflazine | Lidoflazine is a high affinity blocker of the HERG (human ether-a-go-go-related gene) K + channel. Lidoflazine is an antianginal calcium channel blocker that carries a significant risk of QT interval prolongation and ventricular arrhythmia [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3416-26-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-112075. | |
| Liensinine | Liensinine is an autophagy/mitophagy inhibitor. Liensinine, a major isoquinoline alkaloid, extracted from the seed embryo of Nelumbo nucifera Gaertn, has a wide range of biological activities, including anti-arrhythmias, anti-hypertension, anti-pulmonary fibrosis, relaxation on vascular smooth muscle, etc[1]. Uses: Scientific research. Group: Natural products. CAS No. 2586-96-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N0484. | |
| Lifastuzumab | Lifastuzumab is a humanized anti- NaPi2b monoclonal antibody (IgG1 type). Lifastuzumab can be coupled with monomethyl auristatin E (MMAE) through ADC Linker to form an antibody-drug conjugate (ADC) lifastuzumab vedotin (DNIB0600A) with anticancer activity [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1615697-16-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99970. | |
| Lificiguat | Lificiguat binds to the ? subunit of soluble guanylyl cyclase(sGC) with Kd of 0.6-1.1 ?M in the presence of CO. Uses: Scientific research. Group: Signaling pathways. Alternative Names: YC-1. CAS No. 170632-47-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-14927. | |
| Lifirafenib | Lifirafenib (BGB-283) is a novel and potent Raf Kinase and EGFR inhibitor with IC 50 values of 23 and 29 nM for recombinant BRaf V600E and EGFR, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BGB-283. CAS No. 1446090-79-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18957. | |
| Lifitegrast | Lifitegrast (SAR 1118) is a potent integrin antagonist. Lifitegrast blocks the binding of intercellular adhesion molecule 1 (ICAM-1) to lymphocyte function-associated antigen 1 (LFA-1), interrupting the T cell-mediated inflammatory cycle. Lifitegrast inhibits Jurkat T cell attachment to ICAM-1 with an IC 50 of 2.98 nM. Lifitegrast can be used for researching dry eye disease [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SAR 1118; SHP-606. CAS No. 1025967-78-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-19344. | |
| Lifitegrast sodium | Lifitegrast (SAR 1118) sodium is a potent integrin antagonist. Lifitegrast sodium blocks the binding of intercellular adhesion molecule 1 (ICAM-1) to lymphocyte function-associated antigen 1 (LFA-1), interrupting the T cell-mediated inflammatory cycle. Lifitegrast sodium inhibits Jurkat T cell attachment to ICAM-1 with an IC 50 of 2.98 nM. Lifitegrast sodium can be used for researching dry eye disease [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SAR 1118 sodium; SHP-606 sodium. CAS No. 1119276-80-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-19344A. | |
| Ligandrol | Ligandrol (LGD-4033) is a novel nonsteroidal, oral SARM that binds to androgen receptor with high affinity (Ki of 1 nM) and selectivity. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LGD-4033. CAS No. 1165910-22-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13981. | |
| Ligelizumab | Ligelizumab (QGE 031) is a humanized high-affinity monoclonal anti-IgE antibody. Ligelizumab can be used for the research of chronic spontaneous urticarial [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: QGE 031; Anti-IGHE Recombinant Antibody. CAS No. 1322627-61-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99300. | |
| Light green SF yellowish | Light green SF yellowish (Acid Green 5) is a triarylmethane dye. Light green SF yellowish is a highly selective mitochondrial stain. Light green SF yellowish is usually available as a disodium salt and has a maximum absorption value as 629 nm. Light green SF yellowish can be used as a histological stain for collagen and a critical component of Papanicolaou stains [1] [2]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Acid Green 5. CAS No. 5141-20-8. Pack Sizes: 5 g; 10 g. Product ID: HY-126367. | |
| Lignin | Lignin (Lignine) is a natural complex biopolymer with biodegradable and biocompatible. Lignin is the main component of plant cell walls and is a renewable aromatic polymer. Lignin has strongly antioxidant activity [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Lignine. CAS No. 9005-53-2. Pack Sizes: 500 mg; 1 g. Product ID: HY-111830. | |
| Lignin alkali | Lignin alkalie is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 8068-5-1. Pack Sizes: 5 g. Product ID: HY-W250112. | |
| Lignoceric acid | Lignoceric acid (Tetracosanoic acid) is a 24-carbon saturated (24:0) fatty acid, which is synthesized in the developing brain. Lignoceric acid is also a by-product of lignin production. Lignoceric acid can be used for Zellweger cerebro?hepato?renal syndrome and adrenoleukodystrophy research [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Tetracosanoic acid. CAS No. 557-59-5. Pack Sizes: 50 mg; 100 mg. Product ID: HY-121883. | |
| Lignoceryl alcohol | Lignoceryl alcohol is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: 1-Tetracosanol. CAS No. 506-51-4. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-W127492. | |
| Ligufalimab | Ligufalimab (AK 117) is a humanized IgG4 anti-CD47 monoclonal antibody. Ligufalimab does not induce RBC hemagglutination, and induces phagocytosis. Ligufalimab shows anti-tumor activity [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: AK 117. CAS No. 2428381-55-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99706. | |
| Ligustrazine | Ligustrazine (Chuanxiongzine), an alkylpyrazine isolated from Ligusticum chuanxiong Hort. (Chuan Xiong) [1] , is present in french fries, bread, cooked meats, tea, cocoa, coffee, beer, spirits, peanuts, filberts, dairy products and soy products as fragrance and flavouring ingredienexhibits. Ligustrazine also has potential nootropic and anti-inflammatory activities in rats [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Chuanxiongzine; Tetramethylpyrazine. CAS No. 1124-11-4. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-N0264. | |
| Ligustrazine hydrochloride | Ligustrazine (hydrochloride) is a natural product. Uses: Scientific research. Group: Natural products. Alternative Names: Chuanxiongzine hydrochloride; Tetramethylpyrazine hydrochloride. CAS No. 76494-51-4. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0935. | |
| Lilial | Lilial is a widely used synthetic fragrance used as a deodorant [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 80-54-6. Pack Sizes: 10 mM * 1 mL; 25 g. Product ID: HY-W014684. | |
| Lilotomab | Lilotomab (HH1) is a murine anti-CD37 monoclonal antibody. Lilotomab reduces clonogenic survival. Lilotomab shows anti-tumor activity [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: HH1. CAS No. 1453362-55-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99707. | |
| Limantrafin | Limantrafin (CB-103) is a first-in-class, orally active protein-protein interaction (PPI) inhibitor of the NOTCH transcriptional activation complex. Limantrafin has anti-tumor activity[1][2][3][4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CB-103. CAS No. 218457-67-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-135145. | |
| Limaprost | Limaprost (OP1206) is a PGE1 analogue and a potent and orally active vasodilator. Limaprost increases blood flow and inhibits platelet aggregation. Limaprost pain relief, has antianginal effects, and can be used for ischaemic symptoms research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 17α,20-dimethyl-δ2-PGE1; ONO1206; OP1206. CAS No. 74397-12-9. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-B0683. | |
| limertinib | limertinib (ASK120067) is a potent and orally active inhibitor of EGFR T790M ( IC 50 :0.3 nM) with selectivity over EGFR WT (IC 50 :6.0 nM). limertinib is a third-generation EGFR-TKI for the research of non-small cell lung cancer (NSCLC) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ASK120067. CAS No. 1934259-00-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138751. | |
| LIMK-IN-1 | LIMK-IN-1 (Compound 14) is an inhibitor of LIM-Kinase (LIMK) , with IC 50 s of 0.5 nM and 0.9 nM for LIMK1 and LIMK2, respectively. LIMK-IN-1 can be used for ocular hypertension and associated glaucoma research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1116571-01-7. Pack Sizes: 2 mg. Product ID: HY-14227. | |
| (-)-Limonene | (-)-Limonene ((S)-(-)-Limonene) is orally active and can cause mild bronchoconstriction. (-)-Limonene alleviates cytosolic and mitochondrial oxidative stress by inhibiting the increase of calcium ions (Ca 2+ ) and Ca 2+ /calmodulin-dependent protein kinase II (CaMKII). It also exerts anti-stress effects by inhibiting the activity of the hypothalamic-pituitary-adrenal (HPA) axis. Additionally, (-)-Limonene can be used as an antibacterial agent in aquaculture [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: (S)-(-)-Limonene. CAS No. 5989-54-8. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-Z0478. | |
| Limonin | Limonin inhibits HIV-1 with an EC 50 of 60.0 μM. Limonin induces human colon adenocarcinoma cells apoptosis with an IC 50 of 54.74 μM. Limonin has antiviral and antitumor activities [1] [2] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Limonoic acid 3,19:16,17 dilactone. CAS No. 1180-71-8. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-17411. | |
| LIN28 inhibitor LI71 enantiomer | LIN28 inhibitor LI71 enantiomer is the enantiomer of LIN28 inhibitor LI71 with less active. LIN28 inhibitor LI71 is a potent and cell-permeable LIN28 inhibitor, which abolishes LIN28-mediated oligouridylation with an IC 50 of 7 uM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 956189-58-5. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-123905A. | |
| Linaclotide | Linaclotide is a potent and selective guanylate cyclase C agonist; developed for the treatment of constipation-predominant irritable bowel syndrome (IBS-C) and chronic constipation. Uses: Scientific research. Group: Peptides. CAS No. 851199-59-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-17584. | |
| Linagliptin | Linagliptin is a highly potent, selective DPP-4 inhibitor with IC 50 of 1 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BI 1356. CAS No. 668270-12-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-10284. | |
| Linalool | Linalool is a natural monoterpene which is a competitive NMDA receptor antagonist. Linalool is orally active and crosses the blood-brain barrier. Linalool has anticancer, antibacterial, anti-inflammatory, neuroprotective, anxiolytic, antidepressant, anti-stress, cardioprotective, hepatoprotective, nephroprotective and pulmonary protective activities [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. CAS No. 78-70-6. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-N0368. | |
| Linalool oxide | Linalool oxide is a secondary metabolite in elongating wheat plants with antinociceptive and anticonvulsant effects. Linalool oxide shows anxiolytic activity [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 60047-17-8. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-N9502. | |
| Linalyl acetate | Linalyl acetate is the principal components of many plant essential oils with potentially anti-inflammatory activity [1]. Uses: Scientific research. Group: Natural products. CAS No. 115-95-7. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-N6948. | |
| Linamarin | Linamarin, a natural compound, possesses anticancer activity [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Phaseolunatin. CAS No. 554-35-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-123114. | |
| Linaprazan | Linaprazan (AZD0865) can inhibit H+,K+ -ATPase in the stomach through K+ competitive binding, ( IC 50 : 1.0 ± 0.2 μM), it has a strong inhibitory effect on acid. Linaprazan (AZD0865) can be used for research on reflux esophagitis with oral activity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AZD0865. CAS No. 248919-64-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100412. | |
| Linaprazan glurate | Linaprazan glurate inhibits exogenously or endogenously stimulated gastric acid secretion. Linaprazan glurate exhibits several advantageous properties, such as fast onset, high in vivo potency and/or long duration of action. Linaprazan glurate is useful in the research of gastrointestinal inflammatory diseases and peptic ulcer diseases (extracted from patent WO2010063876A1) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: X842. CAS No. 1228559-81-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145578. | |
| Linarin | Linarin (Buddleoside) is an orally active and selective inhibitor of acetylcholinesterase ( AChE ). Linarin has many activities, such as anti-inflammatory, antioxidant, sleep aid and sedation, bone differentiation, anti-tumor, antibacterial and antiviral. Linarin can be used to study diseases such as the nervous system, osteoporosis and cancer [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Buddleoside; Linarine. CAS No. 480-36-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 20 mg. Product ID: HY-N0528. | |
| Linavonkibart | Linavonkibart (SRK 181) is a high-affinity, fully human antibody that selectively binds to latent TGFβ1 and inhibits its activation. Linavonkibart plays an important role in cancer [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: SRK-181. CAS No. 2640981-30-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990069. | |
| Lincomycin | Lincomycin, a lincosamide antibiotic, is an antimicrobial agent used for the research of Gram-positive bacteria infections [1]. Uses: Scientific research. Group: Natural products. Alternative Names: U-10149. CAS No. 154-21-2. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-117660. | |
| Lincomycin hydrochloride | Lincomycin Hydrochloride(U10149A) is an antibiotic produced by Streptomyces lincolnensis var. Uses: Scientific research. Group: Natural products. Alternative Names: U10149A. CAS No. 859-18-7. Pack Sizes: 100 mg. Product ID: HY-B0417A. | |
| Lincomycin hydrochloride monohydrate | Lincomycin hydrochloride monohydrate is a narrow-spectrum antibiotic, has similar effects to erythromycin, which has a good effect on gram-positive coccus, mainly used to inhibit the synthesis of bacterial cell protein [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 7179-49-9. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-B1358. | |
| Linerixibat | Linerixibat (GSK2330672) is a highly potent, nonabsorbable and orally active apical sodium-dependent bile acid transporter (ASBT) inhibitor with an IC 50 of 42 nM human ASBT. Linerixibat can be used as lipid-lowering agent. Linerixibat has the potential for type 2 diabetes and Primary Biliary Cholangitis treatment [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GSK2330672. CAS No. 1345982-69-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16643. | |
| Linezolid | Linezolid (PNU-100766) is the first member of the class of oxazolidinone synthetic antibiotic. Linezolid acts by inhibiting the initiation of bacterial protein synthesis. Linezolid is used for the treatment of serious infections caused by Gram-positive bacteria that are resistant to several other antibiotics [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PNU-100766. CAS No. 165800-03-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10394. | |
| Linezolid-d3 | Linezolid-d 3 is a deuterium labeled Linezolid (PNU-100766). Linezolid is a synthetic antibiotic that acts by inhibiting the initiation of bacterial protein synthesis[1]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: PNU-100766-d3. CAS No. 1127120-38-0. Pack Sizes: 1 mg. Product ID: HY-10394S. | |
| Linezolid (Standard) | Linezolid (Standard) is the analytical standard of Linezolid. This product is intended for research and analytical applications. Linezolid (PNU-100766) is the first member of the class of oxazolidinone synthetic antibiotic. Linezolid acts by inhibiting the initiation of bacterial protein synthesis. Linezolid is used for the treatment of serious infections caused by Gram-positive bacteria that are resistant to several other antibiotics [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PNU-100766 (Standard). CAS No. 165800-03-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10394R. | |
| Linifanib | Linifanib (ABT-869) is a potent and orally active multi-target inhibitor of VEGFR and PDGFR family with IC 50 s of 4, 3, 66, and 4 nM for KDR, FLT1, PDGFRβ, and FLT3, respectively. Linifanib shows prominent antitumor activity. Linifanib has much less activity against unrelated RTKs, soluble tyrosine kinases, or serine/threonine kinases. Linifanib is a specific miR-10b inhibitor that blocks miR-10b biogenesis [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABT-869; AL-39324. CAS No. 796967-16-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-50751. | |
| Linoleate sodium | Linoleate sodium is an orally active IL8 regulator via the JNK and NF-κB pathway. Linoleate sodium can change the composition of fatty acids and the production of metabolites in cells. Linoleate sodium has anti-inflammatory, immune-regulating, and tumor cell growth-affecting activities [1] [2] [3] [4] [5] [6] [7] [8] [9]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 822-17-3. Pack Sizes: 25 mg; 50 mg. Product ID: HY-W011398. | |
| Linoleic acid | Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 60-33-3. Pack Sizes: 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-N0729. | |
| Linoleic acid-13C18 | Linoleic acid- 13 C 18 is the 13 C labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism [1][2]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 287111-25-5. Pack Sizes: 500 μg; 1 mg. Product ID: HY-N0729S2. | |
| Linolelaidic acid | Linolelaidic acid (Linoelaidic acid) is an omega-6 trans fatty acid (TFA) that is an essential nutrient with oral activity. Linolelaidic acid can be added to enteral nutrition (oral), parenteral nutrition (intravenous), and infant formula. Linolelaidic acid has anti-inflammatory and anti-parasitic (( Parasite )) activities, and can induce Apoptosis. Linolelaidic acid is useful for research in infections [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Linoelaidic acid. CAS No. 506-21-8. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-W071746. | |
| Linoleoyl ethanolamide | Linoleoyl ethanolamide (Linoleic acid monoethanolamide) is classified as a fatty acid ethanolamide. Linoleoyl ethanolamide only weakly binds G-protein-coupled cannabinoid receptors of type-1 (CB1) and CB2 receptors, and inhibits the binding of [3H] CP-55,940 with K i s of 10 and 25 μM, respectively. Linoleoyl ethanolamide is 4-fold less potent than anandamide at causing catalepsy in mice and it does not prolong sleep time [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Linoleic acid monoethanolamide. CAS No. 68171-52-8. Pack Sizes: 5 mg. Product ID: HY-113421. | |
| Linoleyl alcohol | Linoleyl alcohol, a structural analog of Linoleic acid with no a-carboxyl group, is a fatty alcohol [1]. Uses: Scientific research. Group: Natural products. CAS No. 506-43-4. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-W005627. | |
| Linoleyl carnitine | Linoleyl carnitine is an acylcarnitine used to study long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency and fatty acid oxidation disorders in fibroblasts [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 36816-10-1. Pack Sizes: 1 mg. Product ID: HY-113256. | |
| Linopirdine | Linopirdine (DuP 996) is an orally active, selective M-type K + current (IM; Kv7; KCNQ Channels) inhibitor with an IC 50 of 2.4 μM. Linopirdine is a TRPV1 agonist. Linopirdine, a putative cognition enhancing agent, increases acetylcholine release in rat brain tissue [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DuP 996. CAS No. 105431-72-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W020468. | |
| Linperlisib | Linperlisib (YY-20394) is a potent, orally bioavailable and selective inhibitor of PI3Kδ extracted from patent WO 2015055071 A1, compound 10; has an IC 50 of 6.4 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: YY-20394. CAS No. 1702816-75-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-102031. | |
| Linrodostat | Linrodostat (BMS-986205) is a selective and irreversible indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor with an IC 50 value of 1.1 nM in IDO1 -HEK293 cells. Linrodostat is well tolerated with potent pharmacodynamic activity in advanced cancers [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-986205; ONO-7701. CAS No. 1923833-60-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101560. | |
| Linsidomine hydrochloride | SIN-1 (chloride) is the active metabolite of molsidomine. SIN-1 (chloride) exhibits potent vasorelaxant effect and inhibition of platelet aggregation [1]. SIN-1 (chloride) decreases myocardial necrosis and reperfusion-induced endothelial dysfunction in models of myocardial ischemia-reperfusion [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SIN-1 chloride. CAS No. 16142-27-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101200. | |
| Linsitinib | Linsitinib (OSI-906) is a potent, selective and orally bioavailable dual inhibitor of the IGF-1 receptor and insulin receptor (IR) with IC 50 s of 35 and 75 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: OSI-906. CAS No. 867160-71-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10191. | |
| Lintuzumab | Lintuzumab (HUM-195) is an anti- CD33 humanized monoclonal antibody. Lintuzumab reduces the production of TNFα-induced pro-inflammatory cytokines and chemokines by AML cells. Lintuzumab promotes tumor cell killing through antibody-dependent cellular cytotoxicity (ADCC) and phagocytosis (ADCP) activities against MDR and MDR+ AML cell lines and primary AML patient samples. Lintuzumab enhances survival and reduces tumor burden in mice [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: HuM-195. CAS No. 166089-32-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9983. | |
| Linuron | Linuron is a phenylurea herbicide that is widely used to control the growth of grass and weeds in various agriculture crops and in orchards. Linuron is a photosystem II inhibitor. Linuron is also a competitive androgen receptor (AR) antagonist with a K i of 100 μM. Linuron shows reproductive toxicity in animals that acts as an endocrine disruptor [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 330-55-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-B1866. | |
| Linvencorvir | Linvencorvir is an antiviral agent [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RG7907. CAS No. 1808248-05-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145579. | |
| Linvoseltamab | Linvoseltamab is a bispecific antibody targeting to both BCMA ( TNFRSF17 ) and CD3 epsilon. Linvoseltamab shows safety profile and encouraging efficacy in relapsed/refractory multiple myeloma (RRMM) models [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: REGN5458. CAS No. 2408319-25-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P9989. | |
| Linzagolix | Linzagolix (KLH-2109; OBE-2109) is a potent, non-peptide, and orally active GnRH antagonist. Linzagolix can be used for uterine fibroids, endometriosis, adenomyosis research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KLH-2109; OBE-2109. CAS No. 935283-04-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109093. | |
| Liothyronine | Liothyronine is an active form of thyroid hormone. Liothyronine binds to thyroid hormone receptors TRα and TRβ with K i s of 2.33 and 2.29 nM for hTRα and hTRβ, respectively. Liothyronine also binds to PVR and blocks the interaction of TIGIT/PVR [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Triiodothyronine; 3,3',5-Triiodo-L-thyronine; T3. CAS No. 6893-2-3. Pack Sizes: 100 mg; 500 mg; 1 g. Product ID: HY-A0070A. | |
| Liothyronine sodium | Liothyronine sodium is an active form of thyroid hormone. Liothyronine sodium is a potent thyroid hormone receptors TRα and TRβ agonist with K i s of 2.33 nM for hTRα and hTRβ, respectively [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Triiodothyronine sodium; 3,3',5-Triiodo-L-thyronine sodium; T3 sodium. CAS No. 55-06-1. Pack Sizes: 100 mg; 500 mg. Product ID: HY-A0070. | |
| Liothyronine sodium hydrate | Liothyronine sodium hydrate is an active form of thyroid hormone. Liothyronine sodium hydrate is a potent thyroid hormone receptors TRα and TRβ agonist with K i s of 2.33 nM for hTRα and hTRβ, respectively [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Triiodothyronine sodium hydrate; 3,3',5-Triiodo-L-thyronine sodium hydrate; T3 sodium hydrate. CAS No. 345957-19-9. Pack Sizes: 100 mg. Product ID: HY-A0070B. | |
| Lipid 29 | Lipid 29 is an ionizable amino lipid. Lipid 29 can be used to form lipid nanoparticles[1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 2244716-55-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148648. | |
| Lipid 5 | Lipid 5 is an amino lipid that affords efficient mRNA delivery in rodent and primate models. Lipid 5 shows optimal pharmacokinetics and non-toxic side effects [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 2089251-33-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138171. | |
| Lipoamide | Lipoamide ((±)-α-Lipoamide) is a monocarboxylic acid derivative of a neutral amide, formed by the condensation of the carboxyl group of lipoic acid and ammonia. Lipoamide protects against oxidative stress-mediated neuronal cell damage and also acts as a coenzyme to transfer acetyl groups and hydrogen during pyruvate deacylation. Lipoamide also stimulates mitochondrial biogenesis in adipocytes through the endothelial NO synthase-cGMP-protein kinase G signaling pathway [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: (±)-α-Lipoamide; DL-Lipoamide; DL-6,8-Thioctamide. CAS No. 940-69-2. Pack Sizes: 100 mg; 500 mg. Product ID: HY-B1142. | |
| Lipofermata | Lipofermata is a fatty acid transport protein 2 (FATP2) inhibitor. Lipofermata shows fatty acid transport inhibition with an IC50 of 4.84 ?M in Caco-2 cells. Lipofermata, an analog of spiro-indoline-thadiazole, shows zinc-specific suppression of antibacterial activity. Lipofermata perturbs zinc homeostasis in E. coli K-12 with a MIC of 16 ?M[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 297180-15-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116788. | |
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