MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| LXE408 | LXE408 is an orally active, non-competitive and kinetoplastid-selective proteasome inhibitor. LXE408 has an IC 50 of 0.04 μM for L. donovani proteasome and an EC 50 of 0.04 μM for L. donovani. LXE408 has a low propensity to cross the blood brain barrier. LXE408 has the potential for visceral leishmaniasis (VL) research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1799330-15-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-131350. |  |
| LXR-623 | LXR-623 is a brain-penetrant partial LXR? and full LXR? agonist, with IC50s of 24 nM and 179 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: WAY 252623. CAS No. 875787-07-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10629. | |
| L-Xylose | L-Xylose (L-(-)-Xylose) is the levo-isomer of Xylose. Xylose is classified as a monosaccharide of the aldopentose type [1]. Uses: Scientific research. Group: Natural products. Alternative Names: L-(-)-Xylose. CAS No. 609-06-3. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-78139. | |
| L-Xylulose | L-Xylulose is an endogenous metabolite present in Blood, Cerebrospinal_Fluid and Urine that can be used for the research of Ribose 5 Phosphate Isomerase Deficiency [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 527-50-4. Pack Sizes: 2.5 mg (1 M * 16.65 μL in Water). Product ID: HY-113317. | |
| LY1 | LY1 is a potent, selective and covalent inhibitor against both SARS-CoV-2 PL pro and M pro with K d values of 1.5 μM and 2.3 μM for M pro C145A protein and PL pro C111A protein, respectively. LY1 potent against the viral proteases, with IC 50 s of 0.12 μM and 0.99 μM against M pro and PL pro. LY1 shows high selectivity over other kinases, human proteases and metalloenzyme [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2883813-32-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-152101. | |
| LY2090314 | LY2090314 is a potent inhibitor of glycogen synthase kinase-3 (GSK-3) with IC50 values of 1.5 nM and 0.9 nM for GSK-3? and GSK-3?, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 603288-22-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16294. | |
| LY2109761 | LY2109761 is an orally active, selective TGF-? receptor type I/II inhibitor with Kis of 38 nM and 300 nM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 700874-71-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-12075. | |
| LY 225910 | LY 225910 is a selective antagonist for cholecystokinin receptor ( CCK2 receptor ), which affects the excitatory response to morphine, and leads to morphine sensitization [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 133040-77-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101352. | |
| LY2452473 | LY2452473 is an orally bioavailable, selective androgen receptor modulator (SARM). Uses: Scientific research. Group: Signaling pathways. CAS No. 1029692-15-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-114530. | |
| LY2510924 | LY2510924 is a potent and selective CXCR4 antagonist that blocks SDF-1 binding to CXCR4 with an IC50 of 0.079 nM. Uses: Scientific research. Group: Peptides. CAS No. 1088715-84-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-12488. | |
| LY-2584702 tosylate salt | LY-2584702 tosylate salt is a selective ATP competitive inhibitor of p70S6K with an IC50 of 4 nM. In S6K1 enzyme assay, the IC50 of LY-2584702 is 2 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1082949-68-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-12493A. | |
| LY-272015 hydrochloride | LY-272015 hydrochloride is an orally active, specific 5-HT 2B receptor antagonist. LY-272015 hydrochloride completely inhibits the phosphorylation of ERK2 induced by 5-HT or BW723C86. LY-272015 hydrochloride is antihypertensive in Deoxycorticosterone Acetate (DOCA)-salt-hypertensive rats [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 172895-15-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100851A. | |
| LY2794193 | LY2794193 is a highly potent and selective mGlu3 receptor agonist (hmGlu3 Ki=0.927 nM?EC50=0.47 nM; hmGlu2 Ki=412 nM?EC50=47.5 nM)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2173037-97-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-119243. | |
| LY2795050 | LY2795050 is a short-acting selective κ(kappa)-opioid receptor (KOR) antagonist. LY2795050 has high affinity for the KOR with K i value of 0.72 nM. LY2795050 can be used for the research of central nervous system dysfunction [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1346133-08-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15708. | |
| LY2857785 | LY2857785 is a type I reversible and competitive ATP kinase inhibitor against CDK9 (IC50 11 nM) and other transcription kinases CDK8 (IC50 16 nM), and CDK7 (IC50 246 nM). Uses: Scientific research. Group: Signaling pathways. CAS No. 1619903-54-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12293. | |
| LY2874455 | LY2874455 is a pan-FGFR inhibitor with IC 50 s of 2.8, 2.6, 6.4, 6 nM for FGFR1 , FGFR2 , FGFR3 , FGFR4 , respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1254473-64-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13304. | |
| LY2880070 | LY2880070 is an orally active CHK1 inhibitor, IC 50 ? 1 nM. LY2880070 can be used as an anticancer agent for combination with DNA damaging agents [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1375637-35-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-148962. | |
| LY2886721 | LY2886721 is a potent, selective and orally active beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor with an IC50 of 20.3 nM for recombinant human BACE1. LY2886721 is selectivity against cathepsin D, pepsin, and renin, but lacking selectivity against BACE2 (IC50 of 10.2 nM). LY2886721 can across blood-brain barrier and has the potential for Alzheimer's disease treatment[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1262036-50-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13240. | |
| LY294002 | LY294002 is a broad-spectrum inhibitor of PI3K with IC 50 s of 0.5, 0.57, and 0.97 μM for PI3Kα , PI3Kδ and PI3Kβ , respectively [1]. LY294002 also inhibits CK2 with an IC 50 of 98 nM [2]. LY294002 is a competitive DNA-PK inhibitor that binds reversibly to the kinase domain of DNA-PK with an IC 50 of 1.4 μM. LY294002 is an apoptosis activator [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 154447-36-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-10108. | |
| LY294002 hydrochloride | LY294002 hydrochloride is a potent and broad-spectrum PI3K inhibitor, with IC 50 values of 0.5, 0.57, and 0.97 μM for P110α , P110δ and P110β , respectively. LY294002 hydrochloride also inhibits CK2 with an IC 50 of 98 nM. LY294002 hydrochloride can be used for pancreatic cancer research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 934389-88-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10108A. | |
| LY2940094 | LY2940094 (BTRX-246040) is a potent, selective and orally available nociceptin receptor (NOP receptor) antagonist with high affinity (Ki=0.105 nM) and antagonist potency (Kb=0.166 nM). LY2940094 reduces ethanol self-administration in animal models[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BTRX-246040. CAS No. 1307245-86-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-114452. | |
| LY 3000328 | LY 3000328 (Z-FL-COCHO) is a potent and selective Cathepsin S (Cat S) inhibitor with IC50s of 7.7 and 1.67 nM for hCat S and mCat S, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Z-FL-COCHO. CAS No. 1373215-15-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-15533. | |
| LY3009120 | LY3009120 (DP-4978) is a pan RAF inhibitor which inhibits BRAF V600E , BRAF WT and CRAF WT with IC 50 s of 5.8, 9.1 and 15 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DP-4978. CAS No. 1454682-72-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12558. | |
| LY3022855 | LY3022855 is a CHO-expressed human antibody that targets CSF1R/M-CSFR/CD115. LY3022855 has a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 150 kDa. The isotype control for LY3022855 can refer to Human IgG1 kappa, Isotype Control (HY-P99001). Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2305770-44-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990619. | |
| LY 303511 hydrochloride | LY 303511 hydrochloride is a structural analogue of LY294002. LY303511 does not inhibit PI3K. LY303511 enhances TRAIL sensitivity of SHEP-1 neuroblastoma cells. LY303511 reversibly blocks K + currents (IC 50 =64.6±9.1 μM) in MIN6 insulinoma cells. Uses: Scientific research. Group: Signaling pathways. CAS No. 2070014-90-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15643A. | |
| LY3154207 | LY3154207 is a potent, subtype selective, and orally available human dopamine D1 receptor positive allosteric modulator (PAM) with minimal allosteric agonist activity ( EC 50 =3 nM) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1638667-79-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-128770. | |
| LY3200882 | LY3200882 is a potent, highly selective, ATP-competitive and orally active TGF-β receptor type 1 (ALK5) inhibitor with an IC 50 of 38.2 nM. LY3200882 inhibits various pro-tumorigenic activities and is also used as an immune modulatory agent [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1898283-02-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103021. | |
| LY3295668 | LY3295668 (AK-01) is a potent, orally active and highly specific Aurora-A kinase inhibitor, with K i values of 0.8 nM and 1038 nM for AurA and AurB, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AK-01. CAS No. 1919888-06-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114258. | |
| LY341495 | LY341495 is a metabotropic glutamate receptor (mGluR) antagonist with IC50s of 21 nM, 14 nM, 7.8 ?M, 8.2 ?M, 170 nM, 990 nM, 22 ?M for mGlu2, mGlu3, mGlu1a, mGlu5a, mGlu8, mGlu7, and mGlu4 receptors, respectively[5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 201943-63-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-70059. | |
| LY 344864 | LY 344864 is a selective, orally active 5-HT 1F receptor agonist with a K i of 6 nM. LY 344864 is a full agonist producing an effect similar in magnitude to serotonin itself. LY 344864 can cross the blood brain barrier to some extent [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 186544-26-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13788. | |
| LY 344864 racemate | LY 344864 racemate is a 5-HT 1F receptor agonist extracted from patent US 5708187 A. Uses: Scientific research. Group: Signaling pathways. CAS No. 186543-64-6. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13788C. | |
| LY 345899 | LY 345899 is a Folate analog and is a methylene tetrahydrofolate dehydrogenase (MTHFD1; DC301) and MTHFD2 inbhibitor with IC50 values of 96 nM and 663 nM, respectively and a Ki of 18 nM for MTHFD1[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 10538-99-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101943. | |
| LY3509754 | LY3509754 (IL-17A inhibitor 1) is a IL-17A inhibitor, with IC50 values of <9.45 nM and 9.3 nM in alphalisa assay and HT-29 cells[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IL-17A inhibitor 1. CAS No. 2452464-73-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-139206. | |
| LY3522348 | KHK-IN-3 (Example 1) is a ketohexokinase ( KHK ) inhibitor. KHK-IN-3 can be used in the study of kidney disease, nonalcoholic steatohepatitis (NASH), diabetes and heart failure. KHK is a rate-limiting enzyme and fructokinase involved in fructose metabolism. KHK catalyzes the phosphorylation of fructose to fructose-1-phosphate (FIP) at the expense of ATP. The lack of feedback inhibition of fructose metabolism triggers the accumulation of downstream intermediates such as lipogenesis, gluconeogenesis, and oxidative phosphorylation [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KHK-IN-3. CAS No. 2568608-48-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-149987. | |
| LY-364947 | LY-364947 (HTS466284) is a potent ATP-competitive inhibitor of TGF?R-I with IC50 of 59 nM, and exhibits 7-fold selectivity over TGF?R-II[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HTS466284. CAS No. 396129-53-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-13462. | |
| LY367385 | LY367385 is a highly selective and potent mGluR1a antagonist. LY367385 has an IC 50 of 8.8 μM for inhibiting of quisqualate-induced phosphoinositide (PI) hydrolysis, compared with >100 μM for mGlu5a. LY367385 has neuroprotective, anticonvulsant and antiepileptic effects [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 198419-91-9. Pack Sizes: 1 mg. Product ID: HY-107515. | |
| (±)-LY367385 | (±)-LY367385 is the racemate of LY367385. LY367385 is a highly potent and selective mGluR1a antagonist. LY367385 has an IC 50 of 8.8 μM for inhibits of quisqualate-induced phosphoinositide (PI) hydrolysis, compared with > 100 μM for mGlu5a [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 198419-90-8. Pack Sizes: 1 mg. Product ID: HY-135464. | |
| LY367385 hydrochloride | LY367385 hydrochloride is a highly selective and potent mGluR1a antagonist. LY367385 hydrochloride has an IC 50 of 8.8 μM for inhibiting of quisqualate-induced phosphoinositide (PI) hydrolysis, compared with >100 μM for mGlu5a. LY367385 hydrochloride has neuroprotective, anticonvulsant and antiepileptic effects [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2829282-00-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107515A. | |
| LY379268 | LY379268 is a potent, selective and brain-penetrant mGlu2/3R agonist with EC50 values of 2.69 nM (mGlu2) and 4.48 nM (mGlu3). LY379268 has no activity on human mGlu 1a, 4a, 5a or 7a receptors. LY379268 has antioxidant and neuroprotective effects[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 191471-52-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103558. | |
| LY393558 | LY393558 is a potent and orally active inhibitor of the 5-HT transporter and an antagonist of 5-HT1B and 5-HT1D receptors. LY393558 increase the extracellular levels of 5-HT in mice model frontal cortex. LY393558 can be used for researching depression [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 271780-64-4. Pack Sizes: 1 mg. Product ID: HY-103089. | |
| LY-404187 | LY-404187 is a potent, selective and centrally active positive allosteric modulator of AMPA receptors , with the EC 50 s of 5.65, 0.15, 1.44, 1.66 and 0.21 μM for GluR1i , GluR2i , GluR2o , GluR3i and GluR4i , respectively. LY-404187 has therapeutic potential in a number of psychiatric disorders and neurodegenerative diseases [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 211311-95-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-13456. | |
| LY-411575 | LY-411575 is a potent ?-secretase inhibitor with IC50 of 0.078 nM/0.082 nM (membrane/cell-based), and also inhibits Notch S3 cleavage with an IC50 of 0.39 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 209984-57-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-50752. | |
| LY456236 | LY456236 is a selective, non-competitive and orally active mGlu1 receptor antagonist that inhibits phosphoinositide hydrolysis with an IC 50 of 0.145 μM. LY456236 also inhibits EGFR with an IC 50 of 0.91 μM [1] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 338736-46-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-103566. | |
| LY487379 | LY487379 is a selective human mGluR2 positive allosteric modulator (PAM). LY487379 potentiates glutamate-stimulated [ 35 S]GTPγS binding with EC 50 values of 1.7 μM and >10 μM for mGlu2 and mGlu3 receptors respectively. LY487379 promotes cognitive flexibility and facilitates behavioral inhibition in a rat model. LY487379 can be used for schizophrenia research [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 353231-17-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122255. | |
| Lycopene | Lycopene is naturally occurring carotenoids found in tomato, tomato products, and in other red fruits and vegetables; exhibits antioxidant effects. Uses: Scientific research. Group: Natural products. CAS No. 502-65-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N0287. | |
| Lycorine | Lycorine is a natural alkaloid extracted from the Amaryllidaceae plant. Lycorine is a potent and orally active SCAP inhibitor with a K d value 15.24 nM. Lycorine downregulates the SCAP protein level without changing its transcription [2]. Lycorine is also a melanoma vasculogenic inhibitor [3]. Lycorine can be used for the study of prostate cancer and metabolic diseases [2]. Uses: Scientific research. Group: Natural products. CAS No. 476-28-8. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-N0288. | |
| Lycorine hydrochloride | Lycorine hydrochloride is the main active ingredient of the herbal medicine derived from Lycoris radiata (LHer.) Herb. and is also a melanoma vasculogenic inhibitor and has anti-tumor activity [1]. Lycorine hydrochloride effectively inhibits mitotic proliferation of Hey1B cells ( IC 50 of 1.2 μM) [2]. Uses: Scientific research. Group: Natural products. CAS No. 2188-68-3. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-N0289. | |
| Lycorine Hydrochloride Monohydrate | Lycorine Hydrochloride Monohydrate is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 6150-58-9. Pack Sizes: 100 mg; 250 mg. Product ID: HY-N0288A. | |
| Lymecycline | Lymecycline is a tetracycline derivative, with broad-spectrum antibacterial activity and also has anti-inflammatory property. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Mucomycin. CAS No. 992-21-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106339. | |
| LYN-1604 | LYN-1604 is a potent UNC-51-like kinase 1 (ULK1) activator (EC50=18.94 nM) for the research of triple negative breast cancer (TNBC)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2088939-99-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101923. | |
| LYN-1604 dihydrochloride | LYN-1604 dihydrochloride is a potent UNC-51-like kinase 1 (ULK1) activator (EC50=18.94 nM) for the research of triple negative breast cancer (TNBC)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2310109-38-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101923B. | |
| Lynestrenol | Lynestrenol is a pregnane X receptor ( PXR ) agonist with the EC 50 s of 41 and 0.23 μM for hPXR and zfPXR, respectively [1]. Lynestrenol, a synthetic progesteronelike agent possess immunostimulatory properties [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 52-76-6. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-109568. | |
| Lys05 | Lys05 (Lys01 trihydrochloride) is a novel lysosomal autophagy inhibitor with IC 50 values of 3.6, 3.8, 6 and 7.9 μM for 1205Lu, c8161, LN229 and HT-29 cell line in the MTT assay. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Lys01 trihydrochloride. CAS No. 1391426-24-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12855A. | |
| Lys-[Des-Arg9]Bradykinin TFA | Lys-[Des-Arg9]Bradykinin TFA, a naturally occurring kinin, is a potent and highly selective bradykinin B1 receptor agonist with a K i of 0.12 nM, 1.7 nM and 0.23 nM for human , mouse and rabbit B1 receptors , respectively. Lys-[Des-Arg9]Bradykinin TFA has low inhibitory activity on B2 receptors [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 2763588-90-3. Pack Sizes: 5 mg; 10 mg; 50 mg. Product ID: HY-103295A. | |
| Lysipressin | Lysipressin (Lysine vasopressin) is antidiuretic hormone that have been found in pigs. Lysipressin activates Oxytocin receptors and adenylate-cyclase. Lysipressin adjusts blood pressure and heart rate. Lysipressin shows antinociceptive activity [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Peptides. Alternative Names: Lysine vasopressin; [Lys8]-Vasopressin. CAS No. 50-57-7. Pack Sizes: 2 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-P0004. | |
| Lysipressin acetate | Lysipressin (Lysine vasopressin) acetate is antidiuretic hormone that have been found in pigs and some marsupial families. Lysipressin acetate induces contraction of the rabbit urinary bladder smooth muscle, activate adenylate-cyclase [1] [2]. Uses: Scientific research. Group: Peptides. Alternative Names: Lysine vasopressin acetate; [Lys8]-Vasopressin acetate. CAS No. 83968-49-4. Pack Sizes: 2 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-P0004A. | |
| Lyso-PAF C-16 | Lyso-PAF C-16 is a substrate of lysoplasmalogen (LysoPls)-specific phospholipase D (LysoPLD). Lyso-PAF C-16 selective acetylates with arachidonic acid [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 52691-62-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-141570. | |
| Lyso-PAF C-18 | Lyso-PAF C-18 is an intermediate for the synthesis of C18-PAF (HY-130345). It has an easily substituted "Lyso-PAF" structure and is easy to purify and has high yield. C18-PAF is a ligand for platelet-activating factor and PAF G protein-coupled receptor (PAFR) and has renovasodilator properties and antihypertensive lipid properties [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 74430-89-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-141581. | |
| LysoPC(14:0/0:0) | LysoPC(14:0/0:0) is a lysophospholipid (LyP). It is a monoglycerophospholipid in which a phosphorylcholine moiety occupies a glycerol substitution site. LysoPC(14:0/0:0) has potent antispasmodic effect[1]. Uses: Scientific research. Group: Natural products. Alternative Names: 14:0 Lyso PC; 1-myristoyl-sn-glycero-3-phosphatidylcholine. CAS No. 20559-16-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113123. | |
| LysoPC(16:1(9Z)) | LysoPC(16:1(9Z)) is a type of lysophosphatidylcholine that can be used to study spleen deficiency syndrome [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 76790-27-7. Pack Sizes: 1 mg (20.26 mM * 100 μL in Ethanol); 5 mg (20.26 mM * 500 μL in Ethanol). Product ID: HY-113470. | |
| Lysophosphatidylcholines | Lysophosphatidylcholines is an orally active lysolipid and a component of oxidized low density lipoprotein (LDL). Lysophosphatidylcholines induces cell injury, the production of IL-1β and apoptosis. Lysophosphatidylcholines has a proactive effect on sepsis [1] [2] [3] [4]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 9008-30-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139414. | |
| Lysophosphatidylethanolamines, egg | Lysophosphatidylethanolamine (LPE) is a naturally-occurring lysophospholipid that can be generated via deacylation of phosphatidylethanolamine by phospholipase A2 (PLA2). It increases the phosphorylation of ERK1/2 in PC12 cells, an effect that can be blocked by the MEK inhibitors U-0126 (HY-12031A) and PD 98059 (HY-12028) and the EGFR inhibitor AG-1478 (HY-13524).1 LPE also increases neurite outgrowth and expression of neurofilament M in PC12 cells. LPE inhibits the activity of phospholipase D (PLD) partially purified from cabbage.3 This product contains lysophosphatidylethanolamine molecular species with variable fatty acyl chain lengths at the sn-1 position and a hydroxy group at the sn-2 position. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Lyso-PE (egg); LPE (egg); L-α-lysophosphatidylethanolamine. CAS No. 97281-40-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-156041. | |
| Lysostaphin | Lysostaphin is an antistaphylococcal agent. Lysostaphin has activities of three enzymes namely, glycylglycine endopeptidase, endo-β-N-acetyl glucosamidase and N-acteyl muramyl-L-alanine amidase [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 9011-93-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P2329. | |
| LysoTracker Blue DND-22 | LysoTracker blue DND-22 is a blue fluorescent dye (Ex/Em: 373/422 nm). LysoTracker blue DND-22 stains acidic regions in living cells. LysoTracker blue DND-22 is used in the researches of neurodegenerative diseases and leukemia[1][2]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 215247-93-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D1775. | |
| LysoTracker Red | LysoTracker Red is a Red fluorescently labeled lysosomal probe with a maximum excitation/emission wavelength of 577/590 nm. The structure is composed of a fluorescein group and linked weak bases, which can freely cross the cell membrane and gather on spherical organelles. It is suitable for observing the internal biosynthesis and related pathogenesis of lysosomes[1]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: LysoTracker Red DND-99. CAS No. 231946-72-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-D1300. | |
| Lysozyme | Lysozyme (Muramidase) is a conserved antimicrobial protein. Lysozyme exerts its bactericidal effect by hydrolyzing bacterial cell wall peptidoglycan (PG). Lysozyme plays an important role in limiting bacterial growth on mucosal surfaces and other sites, not only controlling potential pathogens but also limiting overgrowth of microbiota to prevent dysbiosis. Extracellular lysozyme can also degrade polymeric PG into soluble fragments, activate NOD receptors in mucosal epithelial cells, and lead to the secretion of chemokines and activating factors by neutrophils and macrophages [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Muramidase. CAS No. 9001-63-2. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-P1068. | |
| Lysozyme from chicken egg white | Lysozyme from chicken egg white is a bactericidal enzyme, and it lyses gram-positive bacteria. Lysozyme from chicken egg white can also be used for the research of HIV infection and pulmonary emphysema [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 12650-88-3. Pack Sizes: 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B2237. | |
| Lys-SMCC-DM1 | Lys-SMCC-DM1 (Lys-N?-MCC-DM1) is a agent-linker conjugates for ADC that can inhibit tubulin polymerization. Lys-SMCC-DM1 is the active metabolite of T-DM1. T-DM1 is a HER2-targeting ADC with a tubulin polymerization inhibitor DM1. Lys-SMCC-DM1 can be used in the research of breast cancer[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Lys-N?-MCC-DM1. CAS No. 1281816-04-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-101982. | |
| M-110 | M-110 is a highly selective, ATP-competitive inhibitor of PIM kinases with a preference for PIM-3 (IC 50 =47 nM). M-110 inhibits PIM-1 and PIM-2 with similar IC 50 s of 2.5 μM. M-110 inhibits the proliferation of prostate cancer cell lines with IC 50 s of 0.6 to 0.9 μM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1395048-49-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12830. | |
| M1145 | M1145, a chimeric peptide, is a selective galanin receptor type 2 (GAL2) agonist, with a K i of 6.55 nM. M1145 shows more than 90-fold higher affinity for GAL2 over GAL1 (K i =587 nM) and a 76-fold higher affinity over GalR3 (K i =497 nM). M1145 has an additive effect on the signal transduction of galanin [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1172089-00-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1135. | |
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