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p-Hydroxycinnamic acid
p-Hydroxycinnamic acid, a common dietary phenol, could inhibit platelet activity, with IC 50 s of 371 μM, 126 μM for thromboxane B 2 production and lipopolysaccharide-induced prostaglandin E 2 generation, respectively. Uses: Scientific research. Group: Natural products. CAS No. 7400-08-0. Pack Sizes: 10 mM * 1 mL; 5 g; 10 g. Product ID: HY-N2391.
p-Hydroxymandelic acid
p-Hydroxymandelic acid is a valuable aromatic fine chemical and widely used for production of pharmaceuticals and food additives. Uses: Scientific research. Group: Natural products. CAS No. 1198-84-1. Pack Sizes: 100 mg. Product ID: HY-113027.
Phyllodulcin
Phyllodulcin is an orally active sweetener found in Hydrangea macrophylla var. thunbergii. Phyllodulcin acts as a non-selective phosphodiesterase inhibitor and exerts anti-allergic effects by suppressing lymphocyte activation. Phyllodulcin can be used to combat obesity by regulating levels of leptin, fat browning-related genes, and hypothalamic BDNF-TrkB signaling [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 21499-23-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W044525.
Physcion
Physcion (Parietin), an anthraquinone derivative derived from the traditional Chinese medicine rhubarb, is an effective oral active 6-phosphogluconate dehydrogenase inhibitor with blood-brain barrier permeability, with IC 50 and K d values of 38.5 μM and 26.0 μM, respectively. Additionally, Physcion is an inhibitor of the <>bTLR4/NF-κB signaling pathway, exhibiting anti-inflammatory, antibacterial, and anticancer effects, and can induce Apoptosis and Autophagy in cancer cells [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. Alternative Names: Parietin; Rheochrysidin. CAS No. 521-61-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0108.
Physostigmine
Physostigmine (Eserine) is a reversible acetylcholinesterase (AChE) inhibitor. Physostigmine can crosses the blood-brain barrier and stimulates central cholinergic neurotransmission. Physostigmine can reverse memory deficits in transgenic mice with Alzheimer's disease. Physostigmine is also an antidote for anticholinergic poisoning [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Eserine. CAS No. 57-47-6. Pack Sizes: 1 mg. Product ID: HY-N6608.
Physostigmine salicylate
Physostigmine salicylate (Eserine salicylate) is a reversible acetylcholinesterase (AChE) inhibitor. Physostigmine salicylate crosses the blood-brain barrier and stimulates central cholinergic neurotransmission. Physostigmine salicylate can reverse memory deficits in transgenic mice with Alzheimer's disease. Physostigmine salicylate is also an antidote for anticholinergic poisoning [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Eserine salicylate. CAS No. 57-64-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1266.
Phytanic acid
Phytanic acid is an endogenous metabolite present in Blood that can be used for the research of Zellweger Syndrome, Alpha Methylacyl CoA Racemase Deficiency, Rhizomelic Chondrodysplasia Punctata and Infantile Refsum Disease [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. CAS No. 14721-66-5. Pack Sizes: 5 mg (159.98 mM * 100 μL in Ethanol). Product ID: HY-113067.
Phytic acid (50% in water)
Phytic acid (Inositol hexaphosphate) (50% in water) is a phosphorus storage compound of seeds and cereal grains. Phytic acid (50% in water) is known as a food inhibitor, which has a strong ability to chelate multivalent metal ions, specially zinc, calcium, iron and as with protein residue. Phytic acid (50% in water) inhibits the enzymatic superoxide source xanthine oxidase (XO) , and has antioxidative, neuroprotective, anti-inflammatory effects [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Inositol hexaphosphate; SNF472 free acid. CAS No. 83-86-3. Pack Sizes: 250 mg (757.5 mM * 500 μL in Water). Product ID: HY-N0814.
Phytic acid dodecasodium hydrate
Phytic acid (Inositol hexaphosphate) dodecasodium hydrate is a phosphorus storage compound of seeds and cereal grains. Phytic acid dodecasodium hydrate is known as a food inhibitor, which has a strong ability to chelate multivalent metal ions, specially zinc, calcium, iron and as with protein residue. Phytic acid dodecasodium hydrate inhibits the enzymatic superoxide source xanthine oxidase (XO) , and has antioxidative, neuroprotective, anti-inflammatory effects [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Inositol hexaphosphate dodecasodium hydrate; SNF472 dodecasodium hydrate. CAS No. 123408-98-0. Pack Sizes: 250 mg. Product ID: HY-N0814A.
Phytic acid potassium
Phytic acid potassium is an endogenous metabolite. Uses: Scientific research. Group: Natural products. CAS No. 129832-03-7. Pack Sizes: 10 mM * 1 mL; 100 mg; 1 g. Product ID: HY-W018059.
Phytic acid sodium salt
Phytic acid sodium salt (myo-Inositol; hexakis dihydrogen phosphate; Inositol hexaphosphate) is an orally active compound derived from the seeds of legumes. Phytic acid sodium salt is a [PO4] 3 - storage depot and precursor for other inositol phosphates and pyrophosphates. phytic acid is hydrolyzed by phytases in a stepwise manner in the plant. Phytic acid sodium salt attenuates Aβ oligomers and upregulates autophagy protein. Phytic acid sodium salt can be used in cardiovascular disease, metabolic disease, nervous system disease and cancer research [1] [2] [3] [4] [5] [6] [7] [8] [9] [10]. Uses: Scientific research. Group: Natural products. Alternative Names: myo-Inositol, hexakis(dihydrogen phosphate) sodium salt; Inositol hexaphosphate sodium salt. CAS No. 14306-25-3. Pack Sizes: 500 mg; 1 g. Product ID: HY-N2581.
Phytochelatin 3
Phytochelatin 3 (PC 3) is the small metal chelating peptide that can be used for chelating heavy metals [1]. Uses: Scientific research. Group: Peptides. Alternative Names: PC 3. CAS No. 86220-45-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P3320.
Phytochelatin 5
Phytochelatin 5 is metal-binding compound produced by plants. Phytochelatin 5 may reduce bioavailability of dietary toxic metals such as cadmium [1]. Uses: Scientific research. Group: Peptides. Alternative Names: PC 5. CAS No. 99465-97-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P3322.
Phytohemagglutinin
Phytohemagglutinin (PHA-M), the major seed lectin of the common bean, Phaseolus vulgaris, accumulates in the parenchyma cells of the cotyledons. Phytohemagglutinin is a T-cell activator. Stimulation of human mononuclear leukocytes by Phytohemagglutinin induces the expression of ChAT mRNA, and potentiated ACh synthesis [1]. Uses: Scientific research. Group: Natural products. Alternative Names: PHA-M. CAS No. 9008-97-3. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N7038.
Phytol
Phytol ((E)-Phytol) is an orally active diterpenoid alcohol that can be extracted from chlorophyll. Phytol has antioxidant, anti-inflammatory, anti-schistosomiasis and antibacterial activities [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: (E)?-Phytol. CAS No. 150-86-7. Pack Sizes: 10 mM * 1 mL; 1 g. Product ID: HY-N3075.
Phytosphingosine
Phytosphingosine is a phospholipid with anti-inflammatory, antibacterial, and anti-cancer activities, which can induce apoptosis. Phytosphingosine is an immune regulator and can be used in the study of inflammatory skin diseases. Phytosphingosine is also an activator of GPR120 with an IC 50 value of 33.4 μM and can be used in the study of type II diabetes [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: 4-Hydroxysphinganine. CAS No. 554-62-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W011303.
PI3K/AKT-IN-2
PI3K/AKT-IN-2 (Compound 12c) is a PI3K and AKT inhibitor. PI3K/AKT-IN-2 blocks the epithelial-mesenchymal transition (EMT) and induces apoptosis. PI3K/AKT-IN-2 inhibits the polymerization of tubulin [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2684412-41-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-147768.
PI3Kδ/γ-IN-1
PI3Kδ/γ-IN-1 is a potent, selective PI3K-δ/γ inhibitor for research of hematological malignancies. Uses: Scientific research. Group: Signaling pathways. CAS No. 1980884-01-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144993.
PI3Kδ-IN-16
PI3Kδ-IN-16 is a potent and selective inhibitor of PI3K&delta. PI3Kδ-IN-16 has a strong anti-proliferative effect on cells, causing cell cycle arrest and inducing apoptosis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2766437-35-6. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-155232.
PI3K-IN-32
PI3K-IN-32 (compound 35) is a potent PI3K p110α inhibitor with an pIC 50 of 6.85 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 371934-59-7. Pack Sizes: 5 mg. Product ID: HY-103030.
PI3K-IN-46
PI3K-IN-46 (Intermediate 4) is an intermediate in the synthesis of PI3K inhibitor (2-imino-azolinone-vinyl fused-benzene derivative) that can be used for the research of autoimmune disorders, cardiovascular diseases, and neurodegenerative diseases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 304645-61-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-48869.
PI5P4Kα-IN-1
PI5P4Kα-IN-1 (Compound 13) is a PI5P4K inhibitor ( IC 50 : 2 and 9.4 μM for PI5P4Kα and PI5P4Kβ). PI5P4Kα-IN-1 can be used for research of cancer, metabolic and immunological disorders [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2428737-31-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153531.
PI5P4Kγ-IN-1
PI5P4Kγ-IN-1 (compound 2) is a selective PI5P4Kγ inhibitor. PI5P4Kγ-IN-1 can be used to signal mTORC1 in MCF-7 breast cancer cells and further characterize PI5P4Kγ in the cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2419358-87-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153789.
Piboserod
Piboserod (SB 207266) is a 5-HT4 selective inhibitor of the serotonin receptor. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SB-207266. CAS No. 152811-62-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15574.
Pibrentasvir
Pibrentasvir is a novel and pan-genotypic hepatitis C virus ( HCV ) NS5A inhibitor with EC 50 s ranging from 1.4 to 5.0 pM against HCV replicons containing NS5A from genotypes 1 to 6. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABT-530. CAS No. 1353900-92-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101662.
Picamilon
Picamilon is an orally active derivative of γ-aminobutyric acid that has nootropic effect. Picamilon improves the epilepsy model in rats and promotes correction of functional disorders of the pancreas during Alloxan (HY-W017227)-induced diabetes mellitus in rats [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Nicotinoyl-GABA; Nicotinoyl-γ-aminobutyric acid. CAS No. 34562-97-5. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-107482.
Picankibart
Picankibart is a mouse-derived IgG1κ antibody targeting IL23A [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2622900-74-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990057.
Picaridin
Picaridin (Lcaridin) is a broad spectrum arthropod repellent. Picaridin interacts with mosquito and tick olfactory receptor proteins. Picaridin repels Aedes aegypti. Picaridin exhibits considerable antibacterial , anticandidal and antifungal properties [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Lcaridin. CAS No. 119515-38-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-116144.
Piceatannol
Piceatannol is a well-known Syk inhibitor and reduces the expression of iNOS induced by TNF. Piceatannol is an effective agent for research of acute lung injury (ALI) [1]. Piceatannol is a naturally occurring polyphenolic stilbene found in various fruits and vegetables and exhibits anticancer and anti-inflammatory properties [2]. Piceatannol induces apoptosis in DLBCL cell lines [3]. Piceatannol induces autophagy and apoptosis in MOLT-4 human leukemia cells [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Astringenin; trans-Piceatannol. CAS No. 10083-24-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13518.
Picein
Picein, isolated from Picrorhiza kurroa , is a naturally occurring antioxidant [1]. Uses: Scientific research. Group: Natural products. CAS No. 530-14-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N8698.
Piclamilast
Piclamilast (RP 73401) is a phosphodiesterase 4 (PDE4) inhibitor, with IC 50 values of 16 nM and 2 nM in pig aorta and eosinophil soluble, respectively [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RP 73401; RPR 73401. CAS No. 144035-83-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-12887.
Piclidenoson
Piclidenoson (IB-MECA) is a first-in-class, orally active and selective A3 adenosine receptor (A3AR) agonist. Piclidenoson exhibits antiproliferative effect and induces apoptosis in different cancer cell types like melanoma, leukemia. Piclidenoson can be used for the research of autoimmune inflammatory diseases and COVID-19 [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IB-MECA; CF-101. CAS No. 152918-18-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13591.
Picloram
Picloram is a synthetic auxin herbicide that is widely used to control dicotyledonous weed [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1918-2-1. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-B2034.
Picloram (Standard)
Picloram (Standard) is the analytical standard of Picloram. This product is intended for research and analytical applications. Picloram is an auxinic herbicide that is widely used for controlling broad leaf weeds [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1918-2-1. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B2034R.
Picolinamide
Picolinamide (2-Picolinamide) is an inhibitor of Poly(ADP-ribose) synthetase of nuclei from rat pancreatic islet cells [1] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 2-Picolinamide. CAS No. 1452-77-3. Pack Sizes: 10 mM * 1 mL; 5 g; 10 g; 25 g; 50 g. Product ID: HY-101020.
Picolinic acid
Picolinic acid (PCL 016) is a topical antiviral agent, which inhibits adenovirus replication in rabbits. Uses: Scientific research. Group: Natural products. Alternative Names: PCL 016. CAS No. 98-98-6. Pack Sizes: 10 mM * 1 mL; 500 mg; 5 g. Product ID: HY-I0660.
Picoplatin
Picoplatin (AMD473) is a platinum-based antineoplastic agent. Picoplatin is specifically to circumvent thiol-mediated drug resistance by sterically hindering its reaction with glutathione (GSH) while still retaining the ability to form cytotoxic lesions with DNA [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AMD473; ZD0473. CAS No. 181630-15-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-131468.
Picosulfate sodium salt hydrate
Picosulfate sodium salt hydrate is the hydrate of Sodium Picosulfate (HY-B0544). Picosulfate sodium salt hydrate is an orally active contact irritant laxative. Picosulfate sodium salt hydrate inhibits the absorption of water and electrolytes, increasing their production. Picosulfate sodium salt hydrate can be used in colonoscopy applications [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1307301-38-7. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-107793.
Picotamide
Picotamide is a combined inhibitor of thromboxane A2 (TxA2) synthase and receptor. Picotamide has antiplatelet activity. Picotamide promotes the reduction of microalbuminuria and the inhibition of growth of carotid plaques in diabetes. Picotamide can be used for researching acute or chronic cardiovascular diseases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 32828-81-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-B1735.
Picoxystrobin
Picoxystrobin is a primary strobilurin fungicide that is widely applied for plant disease control. Picoxystrobin inhibits mitochondrial respiration via blocking electron transfer at the Qo center of cytochrome b and c1 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 117428-22-5. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-136355.
Picrocrocin
Picrocrocin, an apocarotenoid found in Saffron. Picrocrocin shows anticancer effect. Picrocrocin exhibits growth inhibitory effects against SKMEL-2 human malignant melanoma cells [1]. Uses: Scientific research. Group: Natural products. CAS No. 138-55-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N4114.
Picropodophyllone
Picropodophyllone, an aryltetralin lignan, is isolated from leaves of Podophyllum hexandrum , and has antifungal activities [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 477-48-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N7684.
Picroside I
Picroside I is the major ingredient of Picrorhiza scrophulariiflora. Picrorhiza scrophulariiflora is a high value medicinal herb due to rich source of hepatoprotective metabolites, Picroside-I and Picroside-II [1]. Picroside I is a promising agent for the management of asthma. Picroside I reduces the inflammation significantly at its higher dose. Picroside I also downregulates pSTAT6 and GATA3 expressions. Picroside I dose-dependently increases the serum levels of IFN-γ [2]. Uses: Scientific research. Group: Natural products. Alternative Names: 6'-Cinnamoylcatalpol. CAS No. 27409-30-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 20 mg. Product ID: HY-N0407.
Picrotoxinin
Picrotoxinin, a potent convulsant, is a chloride channel blocker. Picrotoxinin is a noncompetitive GABA A receptor antagonist, which negatively modulates the action of GABA on GABA A receptors. Picrotoxinin inhibits α 1 β 2 γ 2L GABA A receptor with an IC 50 of 1.15 μM [1]. Uses: Scientific research. Group: Natural products. CAS No. 17617-45-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-B1494.
Pictilisib
Pictilisib (GDC-0941) is a potent inhibitor of PI3Kα/δ with an IC 50 of 3 nM, with modest selectivity against p110β (11-fold) and p110γ (25-fold). Uses: Scientific research. Group: Signaling pathways. Alternative Names: GDC-0941. CAS No. 957054-30-7. Pack Sizes: 10 mM * 1 mL; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-50094.
Pictilisib dimethanesulfonate
Pictilisib dimethanesulfonate (GDC-0941 dimethanesulfonate) is a potent inhibitor of PI3Kα/δ with IC 50 of 3 nM, with modest selectivity against p110β (11-fold) and p110γ (25-fold). Uses: Scientific research. Group: Signaling pathways. Alternative Names: GDC-0941 dimethanesulfonate; GDC-0941 2 MeSO3H salt. CAS No. 957054-33-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-20180.
Pidotimod
Pidotimod is an orally active dipeptide immunostimulant with immunomodulatory properties on the adaptive and the innate immune responses. Pidotimod increases macrophage activity and humoral immune functions. Pidotimod can be used for the research of chronic bronchitis, chronic obstructive pulmonary disease (COPD), bronchiectasis, and chronic idiopathic urticaria,et al [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 121808-62-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0944.
Pifithrin-α hydrobromide
Pifithrin-α hydrobromide is a p53 inhibitor which blocks its transcriptional activity and prevents cells from apoptosis. Pifithrin-α hydrobromide is also an aryl hydrocarbon receptor (AhR) agonist. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Pifithrin hydrobromide; PFTα hydrobromide. CAS No. 63208-82-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15484.
Pifithrin-β hydrobromide
Pifithrin-β hydrobromide (PFT β hydrobromide) is a potent p53 inhibitor with an IC 50 of 23 μM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PFT β hydrobromide; Cyclic Pifithrin-α hydrobromide. CAS No. 511296-88-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16702A.
Piflufolastat
Piflufolastat (DCFPYL) can be used to the preparation of piflufolastat F 18 (DCFPyL F-18). piflufolastat F 18. Piflufolastat F-18 is an 18F-labelled diagnostic imaging agent. Piflufolastat F-18 can be used for positron emission tomography (PET) that targets prostate-specific membrane antigen (PSMA) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DCFPYL. CAS No. 1423758-00-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117756.
Pifusertib hydrochloride
Pifusertib (TAS-117) hydrochloride is a potent, selective, orally active allosteric Akt inhibitor (with IC 50 s of 4.8, 1.6, and 44 nM for Akt1, 2, and 3, respectively). Pifusertib hydrochloride triggers anti-myeloma activities and enhances fatal endoplasmic reticulum (ER) stress induced by proteasome inhibition. Pifusertib hydrochloride induces apoptosis and autophagy [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TAS-117 hydrochloride. CAS No. 2930090-28-9. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-19934A.
Pigment red 170
Pigment Red 170 is a commonly used commercial dye for bulk coloring of plastics and synthetic fibers and for surface coatings such as paints and inks. Uses: Scientific research. Group: Fluorescent dye. CAS No. 2786-76-7. Pack Sizes: 500 mg; 1 g. Product ID: HY-D0278.
Pigment Yellow 14
Pigment Yellow 14 is a fluorescent dye [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 5468-75-7. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-D0281.
Pigment Yellow 83
Pigment Yellow 83 is a yellow colorant [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 5567-15-7. Pack Sizes: 500 mg; 1 g. Product ID: HY-D0283.
PIK-75
PIK-75 is a reversible DNA-PK and p110α -selective inhibitor, which inhibits DNA-PK, p110α and p110γ with IC 50 s of 2, 5.8 and 76 nM, respectively. PIK-75 inhibits p110α >200-fold more potently than p110β (IC 50 =1.3 μM) [1] [2]. PIK-75 induces apoptosis [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 372196-67-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107834.
PIK-75 hydrochloride
PIK-75 hydrochloride is a reversible DNA-PK and p110α -selective inhibitor, which inhibits DNA-PK, p110α and p110γ with IC 50 s of 2, 5.8 and 76 nM, respectively. PIK-75 hydrochloride inhibits p110α >200-fold more potently than p110β (IC 50 =1.3 μM) [1] [2]. PIK-75 hydrochloride induces apoptosis [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 372196-77-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13281.
Piketoprofen
Piketoprofen is a non-steroidal anti-inflammatory reagent that can be used as a cream preparation for the study of soft tissue rheumatism. Piketoprofen-amide is a prodrug of COX-2 inhibitor [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 60576-13-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108297.
Pilaralisib
Pilaralisib (XL147; SAR245408) is a potent and highly selective class I PI3K s inhibitor with IC 50 s of 39 nM, 383 nM, 23 nM and 36 nM for PI3Kα, PI3Kβ, PI3Kγ, and PI3K&delta. Uses: Scientific research. Group: Signaling pathways. Alternative Names: XL-147; SAR245408. CAS No. 934526-89-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16526.
Pilocarpine
Pilocarpine is a selective M3-type muscarinic acetylcholine receptor ( M3 muscarinic receptor ) agonist. Uses: Scientific research. Group: Signaling pathways. CAS No. 92-13-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-B0726A.
Pilocarpine Hydrochloride
Pilocarpine Hydrochloride is a potent M3-type muscarinic acetylcholine receptor ( M3 muscarinic receptor ) agonist. Uses: Scientific research. Group: Natural products. CAS No. 54-71-7. Pack Sizes: 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B0726.
Pilsicainide hydrochloride (SUN-1165) is an orally active sodium channel blocker and potent class Ic antiarrhythmic agent [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: SUN-1165; Pilzicainide(hydrochloride). CAS No. 88069-49-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-101245.
PIM1-IN-1
PIM1-IN-1 is a potent and highly selective PIM1/3 inhibitor, with IC 50 s of 7, 5530 and 70 nM for PIM1, PIM2, and PIM3, respectively, inhibits the phosphorylation of BAD, a downstream target of PIM, with an EC 50 of 262 nM. PIM1-IN-1 shows no obvious effect on FLT3 or hERG binding. Antiproliferative and anti-cancer activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1417630-95-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111552.
PIM447
PIM447 (LGH447) is a potent, orally available, and selective pan- PIM kinase inhibitor, with K i values of 6, 18, and 9 pM for PIM1, PIM2, and PIM3, respectively. PIM447 displays dual antimyeloma and bone-protective effects. PIM447 induces apoptosis [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LGH447. CAS No. 1210608-43-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-19322.
PIM-447 dihydrochloride
PIM447 dihydrochloride (LGH447 dihydrochloride) is a potent, orally available, and selective pan- PIM kinase inhibitor, with K i values of 6, 18, and 9 pM for PIM1, PIM2, and PIM3, respectively. PIM447 dihydrochloride displays dual antimyeloma and bone-protective effects. PIM447 dihydrochloride induces apoptosis [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LGH447 dihydrochloride. CAS No. 1820565-69-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-19322B.
Pimasertib
Pimasertib (AS703026) is a highly selective, ATP non-competitive allosteric orally available MEK1/2 inhibitor [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AS703026; MSC1936369B. CAS No. 1236699-92-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12042.
Pimavanserin
Pimavanserin is a selective inverse agonist of the 5-HT2A receptor with pIC 50 and pK d of 8.73 and 9.3, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ACP-103. CAS No. 706779-91-1. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14557.
Pimavanserin hemitartrate
Pimavanserin (ACP-103) hemitartrate is a potent 5-HT 2A receptor inverse agonist with pIC 50 and pK i of 8.73 and 9.3, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ACP-103 hemitartrate. CAS No. 706782-28-7. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14557A.
Pimecrolimus
Pimecrolimus (SDZ-ASM 981) is a potent, nonsteroid and orally active calcineurin inhibitor with a K i of 117 nM. Pimecrolimus shows anti-inflammatory activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SDZ-ASM 981. CAS No. 137071-32-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-13723.
Pimelic acid
Pimelic acid is the organic compound and its derivatives are involved in the biosynthesis of the amino acid called lysine.Pimelic acid can be used in keratoconus research [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Heptanedioic acid; 1,5-Pentanedicarboxylic acid; 1,7-Heptanedioic acid. CAS No. 111-16-0. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-Y1139.