MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Ponesimod | Ponesimod (ACT-128800) is a potent, selective and orally active agonist of S1P 1 , with an IC 50 of 6 nM in a radioligand binding assay. Ponesimod activates S1P 1 -mediated signal transduction with high potency ( EC 50 =5.7 nM). Ponesimod can protect against lymphocyte-mediated tissue inflammation [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ACT-128800. CAS No. 854107-55-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10569. |  |
| Ponezumab | Ponezumab (PF-04360365) is a humanised anti-amyloid IgG2 monoclonal antibody. Ponezumab reduces Aβ levels in the central nervous system and improves performance in mice in various models of learning and memory. Ponezumab can be used in study of Alzheimer's disease [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: PF-04360365; RN 1219. CAS No. 1178862-65-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99216. | |
| Pongamol | Pongamol (Lanceolatin C) is potent α-glucosidase inhibitor (IC 50 =103.5 μM) and has free-radical (DPPH) scavenging,antihyperglycemic, and antihyperglycemic activities [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Lanceolatin C. CAS No. 484-33-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-121811. | |
| Ponsegromab | Ponsegromab (PF 06946860) is a potent and selective humanized anti- GDF15 monoclonal antibody with anti-cachexia activity. Ponsegromab binds to GDF15 and prevents the binding of GDF15 to GFRAL , thereby blocking GDF15/GFRAL -mediated signaling. Ponsegromab can be used in the research of cancers [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: PF 06946860. CAS No. 2368950-15-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99241. | |
| Porcine dynorphin A(1-13) | Porcine dynorphin A (1-13) is a potent, endogenous κ opioid receptor agonist and is antinociceptive at physiological concentrations. Uses: Scientific research. Group: Peptides. Alternative Names: Dynorphin A Porcine Fragment 1-13. CAS No. 72957-38-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P0088. | |
| Porphobilinogen | Porphobilinogen could act as a phototoxin, a neurotoxin, and a metabotoxin. Uses: Scientific research. Group: Natural products. CAS No. 487-90-1. Pack Sizes: 1 mg. Product ID: HY-W013495. | |
| Porphyrin precursor | Porphyrin precursor is the precursor of Porphyrin for the synthesis of Porphyrin. Porphyrin is a large organic compound containing four modified pyrrole subunits interconnected to each other [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 149365-62-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-117544. | |
| Posaconazole | Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SCH 56592. CAS No. 171228-49-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17373. | |
| Posdinemab | Posdinemab is a humanized IgG1κ antibody, targeting to microtubule-associated protein tau ( MAPT ) [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: JNJ-63733657. CAS No. 2517973-04-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9995. | |
| Potassium 1,2-naphthoquinone-4-sulphonate | Potassium 1,2-naphthoquinone-4-sulphonate (Compound 16) is a 6-phosphogluconate dehydrogenase ( 6PGDH ) inhibitor with an IC 50 of 53 μM. Potassium 1,2-naphthoquinone-4-sulphonate can be used in the study of human African trypanosomiasis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 5908-27-0. Pack Sizes: 1 mg. Product ID: HY-W726137. | |
| Potassium 2,5-dihydroxybenzenesulfonate | Potassium 2,5-dihydroxybenzenesulfonate is a biochemical reagent that can be used as a biological material or organic compound for life science related research [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Potassium 2,5-dihydroxybenzenesulfonate. CAS No. 21799-87-1. Pack Sizes: 25 g. Product ID: HY-W104518. | |
| Potassium bromide, 99% | Potassium bromide, 99% is a salt, widely used as an anticonvulsant and a sedative. Potassium bromide is a redox reagent that can be used to remove peripheral membrane proteins in molecular biology [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 7758-2-3. Pack Sizes: 10 mM * 1 mL; 100 g. Product ID: HY-Y1673. | |
| Potassium chloride, for molecular biology | Potassium chloride, for molecular biology is a potassium chloride that can be used at the molecular level for protein extraction and solubilization. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 7447-40-7. Pack Sizes: 5 g; 25 g. Product ID: HY-Y0537B. | |
| Potassium ferrocyanide trihydrate, 98.5% | Potassium ferrocyanide trihydrate, 98.5% is a biochemical reagent. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Potassium hexacyanoferrate(II) trihydrate. CAS No. 14459-95-1. Pack Sizes: 100 g. Product ID: HY-Y0416. | |
| Potassium hydrogen phthalate | Potassium 2-carboxybenzoate is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 877-24-7. Pack Sizes: 25 g. Product ID: HY-Y0037. | |
| Potassium osmate(VI) dihydrate,99% | Potassium osmate(VI) dihydrate,99% is a biological molecule. Uses: Scientific research. Group: Signaling pathways. CAS No. 10022-66-9. Pack Sizes: 100 mg; 500 mg; 1 g. Product ID: HY-Y0994A. | |
| Potassium sodium tartrate | Potassium sodium tartrate is a chemical compound belonging to the class of organic salts. It is commonly used as a food additive in the food and beverage industry, especially in baking. Potassium sodium tartrate, also known as Rochelle salt, has a variety of applications in industrial settings, such as the production of electronics and textiles. In addition to its uses in industry and food, it is also used in medical applications as a laxative and in some dental preparations. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 304-59-6. Pack Sizes: 50 g; 100 g. Product ID: HY-ER007. | |
| Potassium sorbate | Potassium sorbate (Sorbic acid potassium) is a highly efficient, and nonpoisonous food preservatives. Potassium sorbate generally is an effective inhibitor of most molds and yeasts and some bacteria [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Sorbic acid potassium. CAS No. 24634-61-5. Pack Sizes: 1 g; 5 g. Product ID: HY-N0626A. | |
| Potassium sorbate (Standard) | Potassium sorbate (Standard) is the analytical standard of Potassium sorbate. This product is intended for research and analytical applications. Potassium sorbate (Sorbic acid potassium) is a highly efficient, and nonpoisonous food preservatives. Potassium sorbate generally is an effective inhibitor of most molds and yeasts and some bacteria [1]. Uses: Scientific research. Group: Natural products. CAS No. 24634-61-5. Pack Sizes: 100 mg; 250 mg; 500 mg. Product ID: HY-N0626AR. | |
| Povetacicept | Povetacicept (ALPN-303), an Fc fusion protein of an engineered TACI domain, is a dual APRIL/BAFF antagonist. Povetacicept modulates B lymphocytes and pathogenic autoantibodies for the study of Lupus and other B cell-related autoimmune diseases [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ALPN-303. CAS No. 2490217-42-8. Pack Sizes: 1 mg. Product ID: HY-P990706. | |
| Povidone iodine | Povidone iodine (iodopovidone) displays excellent antibacterial activity which can against MRSA and MSSA strains with MICs of 31.25 mg/L and 7.82 mg/L, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: iodopovidone. CAS No. 25655-41-8. Pack Sizes: 5 g; 25 g. Product ID: HY-B2234. | |
| Povorcitinib | Povorcitinib (INCB54707) is a potent and selective JAK1 inhibitor that effectively reduces abscesses and inflammatory nodules. Povorcitinib is used to study cutaneous lupus erythematosus (CLE) and lichen planus (LP) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: INCB54707. CAS No. 1637677-22-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145588. | |
| Povorcitinib phosphate | Povorcitinib (INCB54707) phosphate is a potent and selective JAK1 inhibitor that effectively reduces abscesses and inflammatory nodules. Povorcitinib phosphate can be used to study cutaneous lupus erythematosus (CLE) and lichen planus (LP) (information extracted from patent WO2021076124A1) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: INCB54707 phosphate. CAS No. 1637677-33-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145588A. | |
| Pozanicline dihydrochloride | Pozanicline dihydrochloride (ABT-089 dihydrochloride) is an orally bioavailable nicotinic acetylcholine receptor ( nAChR ) agonist with a K i of 16.7 nM for binding to [ 3 H]cytisine sites [1]. Pozanicline is an α4β2 -selective nAChR agonist, which binds to rat brain α4β2 nAChR with a K i of 17 nM while binding to α7 nAChR is insignificant [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABT-089 dihydrochloride. CAS No. 161416-61-1. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-110160. | |
| Pozelimab | Pozelimab (REGN3918) is a fully human IgG4 anti-C5 monoclonal antibody. Pozelimab binds to C5 and C5 variants with high affinity and blocks complement-mediated hemolysis. Pozelimab can be used for the research of complement-mediated diseases [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: REGN3918. CAS No. 2096328-94-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99786. | |
| Poziotinib | Poziotinib (HM781-36B) is an orally active, irreversible pan- HER inhibitor, which effectively inhibits EGFR wt , HER-2 and HER-4 with IC 50 s of 3.2, 5.3 and 23.5 nM, respectively. Poziotinib (HM781-36B) also shows excellent inhibitory activities against mutated EGFRs, including EGFR T790M and EGFR L858R/T790M , with IC 50 s of 4.2 and 2.2 nM, respectively. Excellent antitumor activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HM781-36B; NOV120101. CAS No. 1092364-38-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15730. | |
| PP1 | PP1 is a potent, and Src family-selective tyrosine kinase inhibitor with IC 50 of 5 and 6 nM for Lck and Fyn, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AGL 1872; EI 275. CAS No. 172889-26-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13804. | |
| PP2 | PP2 is a reversible and ATP-competitive Src family kinases inhibitor with IC 50 s of 4 and 5 nM for Lck and Fyn , respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AGL 1879. CAS No. 172889-27-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13805. | |
| PP 3 | PP 3 (Compound 3) is an EGFR tyrosine kinase inhibitor with an IC 50 of 2.7 μM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 5334-30-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108484. | |
| PP58 | PP58 is a pyrido[2,3-d]pyrimidine-based compound that inhibits PDGFR , FGFR and Src family activities with nanomolar IC 50 values. Uses: Scientific research. Group: Signaling pathways. CAS No. 212391-58-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18622. | |
| pp60v-src Autophosphorylation site | pp60v-src Autophosphorylation site is a synthetic peptide. pp60v-src Autophosphorylation site can be used for various biochemical studies [1]. Uses: Scientific research. Group: Peptides. CAS No. 81493-98-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P3744. | |
| PPA | PPA is an ADC linker (US20060073528A1). PPA can be used for making antibody-drug conjugate [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 452072-22-9. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-141664. | |
| PPACK TFA | PPACK TFA is a plasminogen activator (rt-PA) inhibitor. PPACK TFA can inhibit changes in fibrin degradation products, plasminogen and alpha 2-antiplasmin. PPACK TFA also inhibits the binding of rt-PA to plasma protease inhibitors [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 157379-44-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122542B. | |
| PPADS tetrasodium | PPADS tetrasodiuma is a non-selective P2X receptor antagonist. PPADS tetrasodiuma blocks recombinant P2X1, -2, -3, -5 with IC 50 s ranging from 1 to 2.6 μM. PPADS tetrasodiuma blocks native P2Y2-like ( IC 50 ~0.9 mM) and recombinant P2Y4 ( IC 50 ~15 mM) receptors. PPADS tetrasodiuma is an inhibitor of the reverse mode of the Na/Ca 2+ exchanger in guinea pig airway smooth muscle [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 192575-19-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-101044. | |
| PPARγ-IN-2 | PPARγ-IN-2 (Compound 5a) is a PPARγ inhibitor. PPARγ-IN-2 inhibits TG accumulation in 3T3-L1 preadipocytes ( EC 50 : 0.106 μM). PPARγ-IN-2 inhibits high-cholesterol diet (HFC)-induced obesity and related metabolic syndrome, and reduces lipid accumulation in adipose tissue [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2682078-97-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-156010. | |
| p,p'-DDD | p,p'-DDD (4,4-DDD) is a major metabolite of p,p'-DDT. p,p'-DDD is an agonist at estrogen receptor α(ERα) and ER&beta. p,p'-DDD increases DNA damage, apoptosis and necrosis in peripheral blood. p,p'-DDD stimulates cell proliferation in SKBR3 cells. p,p'-DDD activates the AP-1 transcription factor. p,p'-DDD can affect sleep times of barbiturates and steroids [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 4,4'-DDD; p,p'-Dichlorodiphenyl dichloroethane. CAS No. 72-54-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg; 500 mg. Product ID: HY-B1984. | |
| p,p'-DDE | p,p'-DDE (4,4'-DDE), a major metabolite of persistent dichlorodiphenyltrichloroethane (DDT), is a potent androgen receptor antagonist, with an IC 50 of 5 μM and a K i of 3.5 μM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 4,4'-DDE; p, p'-Dichlorodiphenyldichloroethylene. CAS No. 72-55-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg; 500 mg. Product ID: HY-B1986. | |
| PPI-2458 | PPI-2458 is a potent, orally active, selective and irreversible inhibitor of methionine aminopeptidase-2 ( MetAP-2 ). PPI-2458 can be used for arthritis and lymphoma research [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 431077-35-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-13731. | |
| PPM1A-IN-1 | PPM1A-IN-1 (Compound IV-4) is an inhibitor for PP2C Ser/Thr phosphatase protein phosphatase Mg2+/Mn2+-dependent 1A. PPM1A-IN-1 exhibits antibacterial activity against Mycobacterium tuberculosis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2919466-30-9. Pack Sizes: 1 mg. Product ID: HY-164220. | |
| PPNDS tetrasodium | PPNDS tetrasodium is a selective and competitive meprin β inhibitor ( IC 50 : 80 nM, K i : 8 nM), and also inhibits ADAM10 ( IC 50 : 1.2 μM). PPNDS tetrasodium is also a P2X1 receptor antagonist. PPNDS is an agonist for the ATP receptor of Paramecium. PPNDS tetrasodium potently inhibits polymerases from viruses. PPNDS tetrasodium can be used in the research of infection and cancers [1] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1021868-77-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-108675. | |
| PPOH | PPOH, a fatty acid derivative, is a selective cyclooxygenase ( COX ) inhibitor that inhibits arachidonic acid cyclooxygenase activity in renal cortical microsomes. In addition, PPOH acts on CYP4A2 and CYP4A3 with the IC 50 values of 22 μM and 6.5 μM, respectively [1]. PPOH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 206052-01-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119647. | |
| PPTN | PPTN is a potent, high-affinity, competitive and highly selective P2Y14 receptor antagonist with a K B value of 434 pM. PPTN exhibits no agonist or antagonist effect at the P2Y1, P2Y2, P2Y4, P2Y6, P2Y11, P2Y12, or P2Y13 receptors. Anti-inflammatory and immune activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1160271-30-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-110322A. | |
| PPTN hydrochloride | PPTN hydrochloride is a potent, high-affinity, competitive and highly selective P2Y14 receptor antagonist with a K B value of 434 pM. PPTN hydrochloride exhibits no agonist or antagonist effect at the P2Y1, P2Y2, P2Y4, P2Y6, P2Y11, P2Y12, or P2Y13 receptors. Anti-inflammatory and anti-immune activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1992047-65-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110322. | |
| PPZ2 | PPZ2 is a diacylglycerol (DAG)-activated TRPC3/TRPC6/TRPC7 channel activator with activity in promoting neuronal development and survival. PPZ2 activates recombinant TRPC3/TRPC6/TRPC7 channels in a dose-dependent manner without affecting other TRPC channels. PPZ2 elicits cation currents and calcium ion (Ca(2+)) influx in cultured central neurons. PPZ2 is able to induce BDNF-like neurite outgrowth and neuroprotection, an effect that disappears after TRPC3/TRPC6/TRPC7 knockdown or inhibition. PPZ2 also increases the activation of the calcium-dependent transcription factor cAMP response element binding protein. The effects of PPZ2 suggest that calcium signaling mediated by activation of DAG-activated TRPC channels plays an important role in its neurotrophic effects [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 896203-18-2. Pack Sizes: 5 mg. Product ID: HY-111527. | |
| PQ-10 | PQ-10 is a potent inhibitor of Phosphodiesterase 10A ( PDE10A ) with IC 50 and ED 50 of 4.6 nM and 13 mg/kg, respectively. PQ-10 induces patterns of brain glucose metabolism which can be a potential translational biomarker. PQ-10 has the potential for researching psychiatric disorders like schizophrenia [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 927691-21-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18078. | |
| PQCA | PQCA is a highly selective and potent muscarinic M1 receptor positive allosteric modulator. PQCA has an EC 50 value of 49 nM and 135 nM on rhesus and human M1 receptor , respectively. PQCA is inactive for other muscarinic receptors. PQCA has potential to reduce the cognitive deficits associated with Alzheimer's disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1144504-35-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-118342. | |
| PqsR/LasR-IN-3 | PqsR/LasR-IN-3 (Compound 7a) is a potent inhibitor of PqsR and LasR systems in P. aeruginosa. PqsR/LasR-IN-3 also inhibits hERG with the IC 50 of 109.01 μM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2581109-51-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-146329. | |
| PR-104 | PR-104 is a selective hypoxia-activated DNA cross-linking agent and can be used for the research of multiple tumor xenograft models. PR-104, as a nitrogen mustard pre-proagent, is converted efficiently to the more lipophilic dinitrobenzamide mustards alcohol PR-104A [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 851627-62-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-16405. | |
| Practolol | Practolol is a potent and selective β1-adrenergic receptor antagonist. Practolol can be used for the research of cardiac arrhythmias [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 6673-35-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119802. | |
| Pradefovir mesylate | Pradefovir mesylate is a good substrate for liver CYP3A4. Pradefovir is converted to 9-(2-phosphonylmethoxyethyl)adenine (PMEA) in human liver microsomes with a K m of 60 μM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Remofovir mesylate. CAS No. 625095-61-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-112690A. | |
| Pradigastat | Pradigastat (LCQ-908) is a selective and orally effective diacylglyceryl acyltransferase 1 (DGAT1) inhibitor with IC 50 at 0.157 μM. Pradigastat is primarily used to study diseases associated with abnormal triglyceride metabolism. Pradigastat has anti-obesity and anti-diabetic effects. Pradigastat inhibited BCRP, OATP1B1, OATP1B3 and OAT3 activities with IC 50 of 5 μM, 1.66μM, 3.34μM and 0.973μM, respectively. In addition, Pradigastat has antiviral activity and can inhibit hepatitis C virus replication in vitro [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LCQ-908. CAS No. 956136-95-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-16278. | |
| Pradofloxacin | Pradofloxacin, a third-generation fluoroquinolone antibacterial agent [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 195532-12-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W753904. | |
| Praeruptorin A | Praeruptorin A is a main bioactive constituent of Peucedanum praeruptorum (also known as Bai-Hua Qian Hu). Praeruptorin A exerts anti-inflammatory effects in vitro through inhibition of NF-κB activation [1]. Uses: Scientific research. Group: Natural products. CAS No. 73069-27-9. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N6065. | |
| Pralatrexate | Pralatrexate is an antifolate and is a potent dihydrofolate reductasean (DHFR) inhibitor with a K i of 13.4 pM. Pralatrexate is a substrate for folylpolyglutamate synthetase with improved cellular uptake and retention. Pralatrexate has antitumor activities and has the potential for relapsed/refractory T-cell lymphoma treatment [1] [2] [3] [4]. Pralatrexate is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 146464-95-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10446. | |
| Praliciguat | Praliciguat (IW-1973) is a potent and orally active soluble guanylate cyclase stimulator, enhances NO signaling, acts as a vasodilator. Praliciguat (IW-1973) stimulates sGC in HEK-293 cells with an EC 50 of 197 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IW-1973. CAS No. 1628730-49-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109039. | |
| Pralidoxime chloride | Pralidoxime chloride is a potent reactivator of acetylcholinesterase (AChE). Pralidoxime chloride reactivates nerve agent-inhibited AChE via direct nucleophilic attack by the oxime moiety on the phosphorus center of the bound nerve agent. Pralidoxime chloride is an antidote for organophosphate poisoning [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 2-PAM chloride. CAS No. 51-15-0. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B1200. | |
| Pralidoxime iodide | Pralidoxime iodide is a potent reactivator of acetylcholinesterase (AChE). Pralidoxime iodide reactivates nerve agent-inhibited AChE via direct nucleophilic attack by the oxime moiety on the phosphorus center of the bound nerve agent. Pralidoxime iodide is an antidote for organophosphate poisoning [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 94-63-3. Pack Sizes: 10 mM * 1 mL; 25 mg; 100 mg; 250 mg. Product ID: HY-B1738A. | |
| Pralsetinib | Pralsetinib (BLU-667) is a highly potent, selective RET inhibitor. Pralsetinib (BLU-667) inhibits WT RET, RET mutants V804L, V804M, M918T and CCDC6-RET fusion with IC 50 s of 0.4, 0.3, 0.4, 0.4, and 0.4 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BLU-667. CAS No. 2097132-94-8. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-112301. | |
| Pramipexole | Pramipexole is a selective and blood-brain barrier (BBB) penetrant dopamine D2-type receptor agonist, with K i s of 2.2 nM, 3.9 nM, 0.5 nM and 1.3 nM for D2-type receptor, D 2 , D 3 and D 4 receptors, respectively. Pramipexole can be used for the research of Parkinson's disease (PD) and restless legs syndrome (RLS) [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 104632-26-0. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-B0410. | |
| Pramipexole dihydrochloride | Pramipexole dihydrochloride is a selective and blood-brain barrier (BBB) penetrant dopamine D2-type receptor agonist, with K i s of 2.2 nM, 3.9 nM, 0.5 nM and 1.3 nM for D2-type receptor, D 2 , D 3 and D 4 receptors, respectively. Pramipexole dihydrochloride can be used for the research of Parkinson's disease (PD) and restless legs syndrome (RLS) [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 104632-25-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17355. | |
| Pramipexole dihydrochloride hydrate | Pramipexole dihydrochloride hydrate is a selective and blood-brain barrier (BBB) penetrant dopamine D2-type receptor agonist, with K i s of 2.2 nM, 3.9 nM, 0.5 nM and 1.3 nM for D2-type receptor, D 2 , D 3 and D 4 receptors, respectively. Pramipexole dihydrochloride hydrate can be used for the research of Parkinson's disease (PD) and restless legs syndrome (RLS) [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 191217-81-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-B0410A. | |
| Pramiracetam | Pramiracetam (CI-879 free base) is a PREP (prolyl endopeptidase) inhibitor. Pramiracetam improves cognitive impairment caused by traumatic brain injury. Pramiracetam can be used in the study of neurodegenerative diseases [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CI-879 free base. CAS No. 68497-62-1. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-17455. | |
| Pramlintide | Pramlintide is a polypeptide analogue of human amylin. Pramlintide, an antidiabetic agent, is antineoplastic in colorectal cancer [1]. Uses: Scientific research. Group: Peptides. CAS No. 151126-32-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P0058. | |
| Pramlintide acetate | Pramlintide acetate is a polypeptide analogue of human amylin. Pramlintide acetate, an antidiabetic agent, is antineoplastic in colorectal cancer [1]. Uses: Scientific research. Group: Peptides. CAS No. 187887-46-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P0058B. | |
| Pramocaine hydrochloride | Pramocaine hydrochloride decreases the permeability of neuronal membranes to sodium ions, blocking both initiation and conduction of nerve impulses. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Pramoxine hydrochloride. CAS No. 637-58-1. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-B1319. | |
| Pranazepide | Pranazepide (FR120480) is a cholecystokinin-A receptor antagonist [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FR120480. CAS No. 150408-73-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-105257. | |
| Pranidipine | Pranidipine (OPC-13340) is a potent, long acting 1,4-dihydropyridine calcium channel blocker with antihypertensive activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: OPC-13340. CAS No. 99522-79-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19664. | |
| Pranlukast | Pranlukast is a highly potent, selective and competitive antagonist of peptide leukotriene s. Pranlukast inhibits [ 3 H]LTE 4 , [ 3 H]LTD 4 , and [ 3 H]LTC 4 bindings to lung membranes with K i s of 0.63±0.11, 0.99±0.19, and 5640±680 nM, respectively. Uses: Scientific research. Group: Natural products. Alternative Names: ONO-1078. CAS No. 103177-37-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0290. | |
| Pranoprofen | Pranoprofen is a non-steroidal anti-inflammatory agent ( NSAID ) for the research of keratitis or other ophthalmology diseases. Pranoprofen inhibit COX-1 and COX-2 enzymes, thus blocking arachidonic acid converted to eicosanoids and reducing prostaglandins synthesis [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 52549-17-4. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B0336. | |
| Prasinezumab | Prasinezumab (PRX 002) is a humanized IgG1 monoclonal antibody directed against aggregated α-synuclein. Prasinezumab has the potential for Parkinson's disease research [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: PRX 002; RG 7935; RO 7046015. CAS No. 1960462-19-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99405. | |
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