MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Morniflumate | Morniflumate (UP 164) is an orally active nonsteroidal anti-inflammatory agent. Morniflumate can be used in the study of inflammatory diseases such as osteoarthritis, painful musculoskeletal disorders and soft tissue inflammation. Uses: Scientific research. Group: Signaling pathways. Alternative Names: UP 164. CAS No. 65847-85-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17488. |  |
| Moronic acid | Moronic Acid is a triterpenoid compound, which is an orally available anti-HIV agent with anti-inflammatory activity. Moronic Acid can inhibit viral replication, with an EC 50 value of <1 μg/mL. Moronic Acid can be isolated from Brazilian propolis [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: (+)-Moronic acid. CAS No. 6713-27-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N3242. | |
| Moroxydine hydrochloride | Moroxydine (ABOB) hydrochloride has multi- antiviral activities against DNA and RNA viruses including influenza symptoms, herpes simplex, varicellazoster, measles, mumps disease, hepatitis C virus, etc. Moroxydine hydrochloride shows high anti-grass carp reovirus (GCRV) activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABOB hydrochloride. CAS No. 3160-91-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B0420A. | |
| Morroniside | Morroniside has neuroprotective effect by inhibiting neuron apoptosis and MMP2/9 expression. Uses: Scientific research. Group: Natural products. CAS No. 25406-64-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N0532. | |
| Morusin | Morusin is a prenylated flavonoid isolated from Morus alba Linn. with various biological activities, such as antitumor, antioxidant, and anti-bacteria property. Morusin could inhibit NF-κB and STAT3 activity. Uses: Scientific research. Group: Natural products. Alternative Names: Mulberrochromene. CAS No. 62596-29-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-N0622. | |
| Mosapride | Mosapride is an orally active gastroenterokinetic compound. Mosapride is a 5HT4 agonist. Mosapride is a CYP inducer. Mosapride has a concentration-dependent inhibitory effect on Kv4.3 , and its IC 50 value is 15.2 μM. Mosapride can be used in the study of gastrointestinal diseases [1] [2] [3] [4] [5] [6] [7]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TAK-370; AS-4370. CAS No. 112885-41-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0189. | |
| Mosapride citrate | Mosapride citrate is an orally active gastroenterokinetic compound. Mosapride citrate is a 5HT4 agonist. Mosapride citrate is a CYP inducer. Mosapride citrate has a concentration-dependent inhibitory effect on Kv4.3 , and its IC 50 value is 15.2 μM. Mosapride citrate can be used in the study of gastrointestinal diseases [1] [2] [3] [4] [5] [6] [7]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TAK-370 citrate; AS-4370 citrate. CAS No. 112885-42-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0189A. | |
| Mosnodenvir | Mosnodenvir (JNJ-1802) is an orally active pan serotype dengue virus (DENV) inhibitor, with EC50 values ranging from 0.057 to 11 nM for four dengue virus (DENV) serotypes. Mosnodenvir blocks viral replication by inhibiting the formation of complexes between two viral proteins, nonstructural protein 3 (NS3) and NS4B, thereby preventing the formation of new viral RNA. Mosnodenvir exhibits picomolar to nanomolar antiviral activity in vitro and has antiviral efficacy in mice and non-human primates[1][2].. Uses: Scientific research. Group: Signaling pathways. Alternative Names: JNJ-1802. CAS No. 2890688-86-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153810. | |
| Mosperafenib | BRAF inhibitor. RG6344 can be used for the study of BRAF V600-mutant solid tumors, such as colorectal cancer (CRC)[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RG6344; RO7276389; B-Raf IN 2. CAS No. 2649372-20-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145120. | |
| Mosunetuzumab | Mosunetuzumab (BTCT-4465A) is a full-length, fully humanized immunoglobulin G1 (IgG1) T-cell-dependent bispecific (TDB) antibody targeting CD20 (B cells) and CD3 (T cells). Mosunetuzumab redirects T cells to engage and eliminate malignant B cells and can be used for the research of relapsed or refractory (R/R) B-cell non-Hodgkin lymphomas (B-NHLs) [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BTCT-4465A. CAS No. 1905409-39-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99033. | |
| Motavizumab | Motavizumab (MEDI-524) is an anti-human RSV ( respiratory syncytial virus ) monoclonal antibody. Motavizumab can be used in respiratory syncytial virus infection in high-risk infants research [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MEDI-524. CAS No. 677010-34-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99209. | |
| Motesanib | Motesanib (AMG 706) is a potent ATP-competitive inhibitor of VEGFR1/2/3 with IC 50 s of 2 nM/3 nM/6 nM, respectively, and has similar activity against Kit, and is appr 10-fold more selective for VEGFR than PDGFR and Ret. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AMG 706. CAS No. 453562-69-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10228. | |
| Motixafortide | Motixafortide (BKT140 4-fluorobenzoyl) is a novel CXCR4 antagonist with an IC 50 vakue of ~1 nM. Uses: Scientific research. Group: Peptides. Alternative Names: BKT140 (4-fluorobenzoyl); BL-8040; TF14016. CAS No. 664334-36-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P0171. | |
| Motolimod | Motolimod (VTX-2337;VTX-378) is a selective Toll-like receptor 8 (TLR8) agonist, with an EC50 of approximately 100 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: VTX-2337; VTX-378. CAS No. 926927-61-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-13773. | |
| MoTP | MoTP is a specific platelet activating factor receptor antagonist and can induce melanocyte ablation. MoTP can be used for the research of cancer. Uses: Scientific research. Group: Signaling pathways. CAS No. 57055-82-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-114745. | |
| MOTS-c (human) | MOTS-c (human) is a biological active peptide. (Recent advances in high-resolution sequencing have led to the discovery of unique peptides derived from mitochondrial genome.1-2 Currently 8 peptides are identified: humanin, mitochondrial open reading frame of the 12S tRNA-c (MOTS-c), and six small humanin-like peptides (SHLP1-6). 1-2 All of these peptides are released into cytosol from mitochondria and associate with increased longevity and cell viability, reduced apoptosis, and other beneficial functions. 1-3 MOTS-c was found to reduce insulin resistance, decrease obesity, and promote homeostasis.). Uses: Scientific research. Group: Peptides. CAS No. 1627580-64-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P2048. | |
| Mouse IgG1 kappa, Isotype Control | Mouse IgG1 kappa, Isotype Control , a mouse monoclonal antibody, is an isotype control for mouse IgG1? antibody. Uses: Scientific research. Group: Inhibitory antibodies. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99977. | |
| Mouse IgG2a kappa, Isotype Control | Mouse IgG2a kappa, Isotype Control, a mouse monoclonal antibody, is an isotype control for mouse IgG2a? antibody. Uses: Scientific research. Group: Inhibitory antibodies. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P99978. | |
| Moveltipril | Moveltipril (Moveltipril calcium; MC-838) is a potent angiotensin converting enzyme (ACE) inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Moveltipril calcium; MC-838. CAS No. 85856-54-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116023. | |
| Moxetumomab | Moxetumomab, a recombinant CD22 -targeting immunotoxin, can be used for the research of hairy cell leukemia (HCL) [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1622075-65-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99034. | |
| Moxidectin | Moxidectin (CL301423) is an orally active macrolide (ML) anthelmintic for the prevention and control of heartworms and roundworms. Moxidectin is also a substrate of BCRP and P-glycoprotein (P-gp) in vivo, and is secreted into breast milk and effluxed from the host and parasite mediated by Bcrp1 and P-gp. This may be related to the presence of chemical residues in milk [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CL301423. CAS No. 113507-06-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-B0777. | |
| Moxifloxacin | Moxifloxacin is an orally active 8-methoxyquinolone antimicrobial for use in the treatment of acute bacterial sinusitis, acute bacterial exacerbations of chronic bronchitis, and community-acquired pneumonia [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 12-8039 free base. CAS No. 151096-09-2. Pack Sizes: 100 mg; 500 mg. Product ID: HY-66011A. | |
| Moxifloxacin-d4 | Moxifloxacin-d 4 is the deuterium labeled Moxifloxacin. Moxifloxacin is an orally active 8-methoxyquinolone antimicrobial for use in the treatment of acute bacterial sinusitis, acute bacterial exacerbations of chronic bronchitis, and community-acquired pneumonia[1][2]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: BAY 12-8039-d4 free base. CAS No. 2596386-23-9. Pack Sizes: 1 mg. Product ID: HY-66011AS. | |
| Moxifloxacin Hydrochloride | Moxifloxacin Hydrochloride (BAY 12-8039) is an oral 8-methoxyquinolone antimicrobial for use in the treatment of acute bacterial sinusitis, acute bacterial exacerbations of chronic bronchitis, and community-acquired pneumonia [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 12-8039. CAS No. 186826-86-8. Pack Sizes: 50 mg; 100 mg; 500 mg. Product ID: HY-66011. | |
| Moxifloxacin (Standard) | Moxifloxacin (Standard) is the analytical standard of Moxifloxacin. This product is intended for research and analytical applications. Moxifloxacin is an orally active 8-methoxyquinolone antimicrobial for use in the treatment of acute bacterial sinusitis, acute bacterial exacerbations of chronic bronchitis, and community-acquired pneumonia [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 151096-09-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-66011AR. | |
| Moxilubant | Moxilubant (CGS-25019C;LTB-019) is an orally active BLT1 antagonist which inhibits LTB4 signaling with a potency of 2 - 4 nM. Moxilubant can be used for cancer research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CGS 25019C free base. CAS No. 146978-48-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-106929. | |
| Moxisylyte hydrochloride | Moxisylyte (hydrochloride) is (alpha 1-blocker) antagonist, it can vasodilates cerebral vessels without reducing blood pressure. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Thymoxamine hydrochloride. CAS No. 964-52-3. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-B1435. | |
| Moxonidine | Moxonidine (BDF5895) is an imidazoline type 1 receptor (I1-R) selective agonist and antihypertensive agent. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BDF5895. CAS No. 75438-57-2. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B0374. | |
| Moxonidine hydrochloride | Moxonidine Hydrochloride is a selective agonist at the imidazoline receptor subtype 1, used as antihypertensive agent. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BDF5895 hydrochloride. CAS No. 75536-04-8. Pack Sizes: 10 mM * 1 mL; 5 mg. Product ID: HY-B0374A. | |
| MP265 | MP265 (4-Chlorobenzyl carbamimidothioate hydrochloride) is a structural analogue of A22 but is less toxic. MP265 is a MreB inhibitor[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 4-Chlorobenzyl carbamimidothioate hydrochloride. CAS No. 544-47-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-131583. | |
| MP7 | MP7 (PDK1 inhibitor) is a phosphoinositide-dependent kinase-1 ( PDK1 ) inhibitor. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PDK1 inhibitor. CAS No. 1001409-50-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14440. | |
| m-PEG12-acid | m-PEG12-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2135793-73-4. Pack Sizes: 50 mg; 100 mg; 250 mg. Product ID: HY-135820. | |
| m-PEG12-amine | m-PEG12-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs [1]. m-PEG12-amine is also a non-cleavable 12 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1977493-48-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-140227. | |
| m-PEG4-NHS ester | m-PEG4-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Uses: Scientific research. Group: Signaling pathways. CAS No. 622405-78-1. Pack Sizes: 100 mg; 250 mg; 500 mg. Product ID: HY-124323. | |
| mPEG-amine (MW 2000) | mPEG-amine (mPEG-NH2) (MW 2000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: mPEG-NH2 (MW 2000). CAS No. 80506-64-5. Pack Sizes: 50 mg; 100 mg. Product ID: HY-140676. | |
| mPEG-amine (MW 5000) | mPEG-amine (mPEG-NH2) (MW 5000) is a modifier that can replace the sulfonic acid portion of the dye molecule to increase the water solubility of long-wavelength voltage-sensitive dyes (VSD) or Pittsburgh (PGH) dyes. mPEG-amine can also form amide bonds with carboxyl groups on the surface of microspheres under the mediation of EDC and Sulfo-NHS to form a PEG coating on the surface of fluorescent microspheres for large-scale rotational cytoplasmic flow studies [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: mPEG-NH2 (MW 5000). CAS No. 80506-64-5. Pack Sizes: 100 mg; 250 mg. Product ID: HY-140677. | |
| m-PEG-DMG (MW 2000) | m-PEG-DMG (MW 2000) is a PEG lipid for the preparation of liposomes and can be used in drug delivery studies [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 1019000-64-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-W440821. | |
| m-PEG-NHS ester (MW 5000) | m-PEG-NHS ester (MW 5000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: mPEG-SC (MW 5000); mPEG-Succinimidyl ester (MW 5000). CAS No. 92451-01-9. Pack Sizes: 50 mg; 100 mg. Product ID: HY-140698. | |
| mPEG-PLGA | mPEG-PLGA is a mucus-penetrating polymer. mPEG-PLGA is a raw material to prepare nanomedicine [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 743423-15-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-164077. | |
| m-PEG-thiol (MW 1000) | m-PEG-thiol (MW 1000) is a surface modifier that can modify DNA thiolation and is used in the synthesis of gold nanorods (AuNR). m-PEG-thiol (MW 1000) can load thiolated DNA onto AuNR, form a covalent bond with the surface of gold nanoparticles through the thiol group, and stabilize the nanoparticles by the steric hindrance effect of the polyethylene glycol chain, preventing aggregation and enhancing its biocompatibility. m-PEG-thiol (MW 1000) can also provide a platform for the subsequent coupling of biomolecules (such as DNA, antibodies) by replacing surfactants (such as CTAB) on the surface of nanoparticles, thereby exerting its activity in promoting the functionalization of nanomaterials[1][2]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: mPEG-SH (MW 1000). CAS No. 134874-49-0. Pack Sizes: 50 mg; 100 mg. Product ID: HY-W591476. | |
| MPEP | MPEP is a potent, selective, noncompetitive, orally active and systemically active mGlu5 receptor antagonist, with an IC 50 of 36 nM for completely inhibiting quisqualate-stimulated phosphoinositide (PI) hydrolysis. MPEP has anxiolytic-or antidepressant-like effects [1] [2]. MPEP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 96206-92-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14609A. | |
| MPEP Hydrochloride | MPEP Hydrochloride is a potent, selective, noncompetitive, orally active and systemically active mGlu5 receptor antagonist, with an IC 50 of 36 nM for completely inhibiting quisqualate-stimulated phosphoinositide (PI) hydrolysis. MPEP Hydrochloride has anxiolytic-or antidepressant-like effects [1] [2]. MPEP (Hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 219911-35-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14609. | |
| MPH-220 | MPH-220 is a selective and orally active inhibitor of skeletal muscle myosin-2. MPH-220 enables muscle relaxation. MPH-220 is anti-spastic agent that can be used in the research of spasticity and muscle stiffness[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2649776-79-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148516. | |
| MPI-0479605 | MPI-0479605 is a potent and selective ATP-competitive inhibitor of Mps1, with an IC50 of 1.8 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1246529-32-7. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12660. | |
| MPP dihydrochloride | MPP dihydrochloride is a potent and selective ER (estrogen receptor) modulator. MPP dihydrochloride induces significant apoptosis in the endometrial cancer and oLE cell lines. MPP dihydrochloride reverses the positive effects of beta-estradiol. MPP dihydrochloride has mixed agonist/antagonist action on murine uterine ERalpha in vivo [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 911295-24-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103454. | |
| MPP hydrochloride | MPP hydrochloride is a potent and selective ER (estrogen receptor) modulator. MPP hydrochloride induces significant apoptosis in the endometrial cancer and oLE cell lines. MPP hydrochloride reverses the the positive effects of beta-estradiol. MPP hydrochloride has mixed agonist/antagonist action on murine uterine ERalpha in vivo [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2863676-89-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103454B. | |
| MPP+ iodide | MPP+ iodide, a toxic metabolite of the neurotoxin MPTP, causes symptom of Parkinson's disease in animal models by selectively destroying dopaminergic neurons in substantia nigra. MPP+ iodide is taken up by the dopamine transporter into dopaminergic neurons where it exerts its neurotoxic action on mitochondria by affecting complex I of the respiratory chain. MPP+ iodide is also a high affinity substrate for the serotonin transporter (SERT) [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 36913-39-0. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W008719. | |
| Mps1-IN-3 | Mps1-IN-3 is a potent and selective MPS1 kinase inhibitor, with an IC 50 of 50 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1609584-72-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12401. | |
| Mps1-IN-3 hydrochloride | Mps1-IN-3 hydrochloride is a potent and selective Mps1 inhibitor with an IC 50 value of 50 nM. Mps1-IN-3 hydrochloride can inhibit the proliferation of glioblastoma cells, and effectively sensitizes glioblastomas to Vincristine in orthotopic glioblastoma xenograft model [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2989453-29-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12401A. | |
| MPT0G211 | MPT0G211 is a potent, orally active and selective HDAC6 inhibitor ( IC 50=0.291 nM). MPT0G211 displays >1000-fold selective for HDAC6 over other HDAC isoforms. MPT0G211 can penetrate the blood-brain barrier. MPT0G211 ameliorates tau phosphorylation and cognitive deficits in an Alzheimers disease model. MPT0G211 has anti-metastatic and neuroprotective effects. Anticancer activities [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2151853-97-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-123976. | |
| MPTP hydrochloride | MPTP hydrochloride is a brain penetrant dopamine neurotoxin. MPTP hydrochloride can be used to induces Parkinsons Disease model. MPTP hydrochloride, a precusor of MPP + , induces apoptosis [1] [2] [3]. MPTP hydrochloride has been verified by MCE with professional biological experiments. Uses: Scientific research. Group: Signaling pathways. CAS No. 23007-85-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-15608. | |
| MQAE | MQAE is a chloride ion (Cl - ) fluorescent probe that can be used to measure chloride concentrations. The fluorescence intensity of MQAE decreases proportionally as Cl - ions increase. MQAE has high cell permeability and is suitable for fluorescence detection such as confocal microscopy and flow cytometry (Ex/Em=350/460 nm) [1] [2]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 162558-52-3. Pack Sizes: 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-D0090. | |
| MrgprX2 antagonist-1 | MrgprX2 antagonist-1 is an MrgprX2 antagonist extracted from patent WO2021092264A1, example E23. MrgprX2 antagonist-1 can be used for the research of inflammatory disorders of the skin[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2642162-06-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145191. | |
| MrgprX2 antagonist-2 | MrgprX2 antagonist-2 is an MrgprX2 antagonist extracted from patent WO2021092262A1, example E163. MrgprX2 antagonist-2 can be used for the research of inflammatory disorders of the skin[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2642346-30-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-145192. | |
| MRK-560 | MRK-560 is an orally active, brain barrier-penetrated ?-Secretase inhibitor, reducing A? peptide in rat brain and cerebrospinal fluid. MRK-560 decreases mutant NOTCH1 processing by selectively inhibiting PSEN1. MRK-560 can be used in studies of Alzheimer's disease and T-cell acute lymphoblastic leukaemia (T-ALL)[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 677772-84-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14174. | |
| MRK-740 | MRK-740 is a potent, selective and substrate-competitive PRDM9 histone methyltransferase inhibitor with an IC50 of 80?nM. MRK-740 is more selective for PRDM9 than other histone methyltransferases and other non-epigenetic targets. MRK-740 reduces PRDM9-dependent trimethylation of H3K4 (IC50?=?0.8?μM)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2387510-80-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114209. | |
| MR-L2 | MR-L2 is a reversible and noncompetitive allosteric activator of long-isoform phosphodiesterase-4 (PDE4), activates representative PDE4 long-isoform variants (PDE4A4, PDE4B1, PDE4C3, PDE4D5). MR-L2 suppresses PGE2-induced MDCK cell cyst formation with an EC50 of 1.2 ?M[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2374703-19-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-128358. | |
| MRL-494 hydrochloride | MRL-494 hydrochloride, an antibacterial agent, is a inhibitor of β-barrel assembly machine A (BamA) impervious to efflux and the outer membrane permeability barrier. MRL-494 hydrochloride can inhibits Gram-positive (MIC of 12.5 μM for Staphylococcus aureus COL) and Gram-negative (MIC of 25 μM for E. coli JCM158) bacterias [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2699937-04-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128773A. | |
| MRS1220 | MRS1220, a highly potent and selective human A3 adenosine receptor (hA3AR) antagonist with a Ki of 0.59 nM, has therapeutic potential for the research of diseases of the central nervous system[1]. MRS1220 reduces glioblastoma tumor size and blood vessel formation in vivo[2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 183721-15-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103190. | |
| MRS 1523 | MRS 1523 is a potent and selective adenosine A3 receptor antagonist with Ki values of 18.9 nM and 113 nM for human and rat A3 receptors, respectively. In rat this corresponds to selectivities of 140- and 18-fold vs A1 and A2A receptors, respectively. MRS 1523 can exert antihyperalgesic effect through N-type Ca channel block and action potential inhibition in isolated rat dorsal root ganglion (DRG) neurons[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 212329-37-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-121119. | |
| MRS 1754 | MRS 1754 is a selective antagonist radioligand for A2B adenosine receptor with very low affinity for A1 and A3 receptors of both humans and rats[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 264622-58-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14121. | |
| MRS2179 tetrasodium hydrate | MRS2179 tetrasodium hydrate is a competitive P2Y1 receptor antagonist, with a Kb of 102 nM and a pA2 of 6.99 for turkey P2Y1 receptor. MRS2179 tetrasodium hydrate is selective for P2Y1 over P2X1 (IC50=1.15 μM), P2X3 (12.9 μM), P2X2, P2X4, P2Y2, P2Y4, and P2Y6 receptors[1][2]. MRS2179 tetrasodium hydrate inhibits platelet aggregation[3]. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 1 mg; 5 mg. Product ID: HY-101308A. | |
| MRT199665 | MRT199665 is a potent and ATP-competitive, selective MARK/SIK/AMPK inhibitor with IC50s of 2/2/3/2 nM, 10/10 nM, and 110/12/43 nM for MARK1/MARK2/MARK3/MARK14, AMPK?1/AMPK?2, and SIK1/SIK2/SIK3, respectively[1]. MRT199665 causes apoptosis in MEF2C-activated human acute myeloid leukemias (AML) cells[2]. MRT199665 inhibits the phosphorylation of SIK substrate CRTC3 at S370[3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1456858-57-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-120877. | |
| MRT-2359 | MRT-2359 is a potent, orally active and selective GSPT1 depressant (IC50: >30 nM and <300 nM) that specifically induces apoptosis dependent on protein translation. MRT-2359 exhibits significant and preferred anti-proliferative activity in a variety of cancer cell lines, especially MYC-driven cell lines, such as non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC) with high expression of N-Myc or L-Myc. MRT-2359 inhibits the growth of drug-resistant NSCLC and SCLC cells, making it suitable for cancer research[1][2][3][4][5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2803881-11-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153356. | |
| MRT67307 | MRT67307 is a dual inhibitor of the IKKε and TBK-1 with IC 50 s of 160 and 19 nM, respectively [1]. MRT67307 also inhibits ULK1 and ULK2 with IC 50 s of 45 and 38 nM, respectively. MRT67307 also blocks autophagy in cells [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1190378-57-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13018. | |
| MRT68921 | MRT68921 is a potent inhibitor of ULK1 and ULK2, with IC50 values of 2.9 nM and 1.1 nM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1190379-70-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-100006. | |
| MRT68921 dihydrochloride | MRT68921 dihydrochloride is a potent inhibitor of ULK1 and ULK2, with IC50 values of 2.9 nM and 1.1 nM, respectively[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2080306-21-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100006A. | |
| MRT-83 | MRT-83 is a potent antagonist of Smo , with an IC 50 in the nanomolar range. MRT-83 also blocks Hedgehog (Hh) signaling. Uses: Scientific research. Group: Signaling pathways. CAS No. 1263131-92-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18287. | |
| MRT-83 hydrochloride | MRT-83 (hydrochloride) is the potent antagonist of Smoothened ( Smo ) receptor. MRT-83 (hydrochloride) inhibits the Hedgehog (Hh) signaling pathway and BODIPY-cyclopamine binding to human Smo. MRT-83 (hydrochloride) has the potential for researching cancer disease [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1359944-60-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18287A. | |
| MRTX0902 | MRTX0902 is an orally active and potent SOS1 inhibitor with an IC 50 of 46 nM (WO2021127429A1; Example 12-10) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2654743-22-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145926. | |
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