MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| N-Acetylprocainamide hydrochloride | N-Acetylprocainamide (Acecainide) hydrochloride is a class III antiarrhythmic, which blocks K + channels [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Acecainide hydrochloride; NAPA hydrochloride. CAS No. 34118-92-8. Pack Sizes: 5 mg; 10 mg; 50 mg. Product ID: HY-101433. |  |
| N-Acetylputrescine | N-Acetylputrescine (NAP) is an endogenous metabolite widely present in animals and plants. N-Acetylputrescine can be used as a biomarker for lung squamous cell carcinoma (SCCL) and Parkinson's disease (PD) for disease diagnosis [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: NAP. CAS No. 5699-41-2. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-W342604. | |
| N-Acetylputrescine hydrochloride | N-Acetylputrescine hydrochloride is a putrescine derivative. Uses: Scientific research. Group: Natural products. CAS No. 18233-70-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113100. | |
| N-Acetyltaurine | N-Acetyltaurine is a sulfonate that can serve as a carbon source or a nitrogen source, and an energy source for microbial growth (such as the NAT strain). Additionally, N-Acetyltaurine is also a substrate for the amidase enzyme, porcine kidney N-acetyl-β-alanine deacetylase [EC 3.5.1.21] [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 19213-70-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W587486. | |
| N-Acetyltyramine | N-Acetyltyramine is a quorum-sensing inhibitor (QSI) compound produced by V. alginolyticus M3-10. N-Acetyltyramine is capable of inhibiting the QS of C. violaceum ATCC 12472. N-acetyltyramine reverses resistance in Doxorubicin-resistant leukemia P388 cells [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1202-66-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-120504. | |
| NAcM-OPT | NAcM-OPT is an orally bioavailable cullin neddylation 1 (DCN1) inhibitor, which potently inhibits the DCN1-UBE2M interaction[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2089293-61-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-111505. | |
| Nacubactam | Nacubactam (OP0595 free acid) is a potent non-β-lactam-β-lactamase inhibitor with activity against class A and class C β-lactamases. Nacubactam (OP0595 free acid) acts as a penicillin binding protein (PBP) 2-active antibacterial, and gives β-lactamase-independent potentiation of β-lactams targeting other PBPs [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: OP0595 free acid. CAS No. 1452458-86-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-109008. | |
| NAD+ | NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. Uses: Scientific research. Group: Natural products. Alternative Names: β-DPN; β-NAD; β-Nicotinamide Adenine Dinucleotide. CAS No. 53-84-9. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0445. | |
| NADase | NADase is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Signaling pathways. CAS No. 9032-65-9. Pack Sizes: 10 g; 1 g; 5 g. Product ID: HY-P2940. | |
| NAD+-d4 | NAD+-d4 is the deuterium-labeled NAD+ (HY-B0445). NAD+-d4 is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: ?-DPN-d4; ?-NAD-d4; ?-Nicotinamide Adenine Dinucleotide-d4. Pack Sizes: 500 ?g. Product ID: HY-W654288. | |
| NADH disodium salt | NADH disodium salt (Disodium NADH) is an orally active reduced coenzyme. NADH disodium salt is a donor of ADP-ribose units in ADP-ribosylaton reactions and a precursor of cyclic ADP-ribose. NADH disodium salt plays a role as a regenerative electron donor in cellular energy metabolism, including glycolysis, ?-oxidation and the tricarboxylic acid (TCA) cycle[1]. Uses: Scientific research. Group: Natural products. Alternative Names: Disodium NADH. CAS No. 606-68-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-F0001. | |
| Nadifloxacin | Nadifloxacin (OPC7251) is a broad-spectrum fluoroquinolone antibiotic that is effective against acne vulgaris. Uses: Scientific research. Group: Signaling pathways. Alternative Names: OPC7251. CAS No. 124858-35-1. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-B0506. | |
| Nadolol | Nadolol (SQ-11725) is a non-selective and orally active β-adrenergic receptors blocker and is a substrate of organic anion transporting polypeptide 1A2 (OATP1A2). Nadolol has the the potential for high blood pressure, angina pectoris and vascular headaches research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SQ-11725. CAS No. 42200-33-9. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-B0804. | |
| NADP | NADP is a coenzyme involved in cellular electron transfer reactions in biological metabolism, which is alternately oxidized (NADP+) and reduced (NADPH), and can maintain cellular redox homeostasis and regulate many biological events, including cellular metabolism. NADPH is a universal electron donor that provides reducing ability for synthetic metabolic reactions and redox balance. NADPH plays a multifunctional role in regulating inflammation, redox homeostasis, and synthetic metabolism processes [1] [4]. Uses: Scientific research. Group: Natural products. CAS No. 53-59-8. Pack Sizes: 50 mg; 100 mg; 500 mg. Product ID: HY-113325. | |
| NADP disodium salt | NADP disodium salt is the disodium salt form of NADP (HY-113325). NADP is a coenzyme involved in cellular electron transfer reactions in biological metabolism, which is alternately oxidized (NADP+) and reduced (NADPH), and can maintain cellular redox homeostasis and regulate many biological events, including cellular metabolism. NADPH is a universal electron donor that provides reducing ability for synthetic metabolic reactions and redox balance. NADPH plays a multifunctional role in regulating inflammation, redox homeostasis, and synthetic metabolism processes[1][4].. Uses: Scientific research. Group: Natural products. Alternative Names: Disodium NADP. CAS No. 24292-60-2. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-F0002A. | |
| NADPH | NADPH is an essential electron donor in organisms, providing reducing power for anabolic reactions and redox balance, with potential applications in electrosynthesis. The cellular NADPH homeostasis is associated with tumorigenesis. As a key factor in the cellular antioxidant system, NADPH can mediate cell death through its effects on oxidative stress. This approach, based on NADPH-regulated metabolism, holds promise for research in the field of cancer therapy [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 53-57-6. Pack Sizes: 50 mg; 100 mg. Product ID: HY-113324. | |
| NAD(P)H-Nitrate reductase | NAD(P)H-Nitrate reductase is isolated from Aspergillus niger that catalyses the reduction of nitrate to nitrite via a two-electron transfer. In plants, the electron donor for Nitrate reductase is NADPH is NADH:Nitrate reductase and a bispecific NAD(P)H: Nitrate reductase [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 9029-27-0. Pack Sizes: 1 U. Product ID: HY-P2996. | |
| NADPH tetrasodium salt | NADPH tetrasodium salt functions as an important cofactor in a variety of metabolic and biosynthetic pathways. NADPH tetrasodium salt is an endogenous inhibitor of ferroptosis. NADPH tetrasodium salt plays a vital role in the biosynthesis of agents, chiral alcohols, fatty acids and biopolymers, while also being required for lipid biosynthesis, biomass formation, and cell replication[1][2][3][4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2646-71-1. Pack Sizes: 50 mg; 100 mg. Product ID: HY-F0003. | |
| NADP sodium hydrate | NADP sodium hydrate is the sodium salt hydrate form of NADP (HY-113325). NADP is a coenzyme involved in cellular electron transfer reactions in biological metabolism, which is alternately oxidized (NADP+) and reduced (NADPH), and can maintain cellular redox homeostasis and regulate many biological events, including cellular metabolism. NADPH is a universal electron donor that provides reducing ability for synthetic metabolic reactions and redox balance. NADPH plays a multifunctional role in regulating inflammation, redox homeostasis, and synthetic metabolism processes [1] [4]. Uses: Scientific research. Group: Natural products. CAS No. 698999-85-8. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-113325A. | |
| NADP sodium salt | NADP sodium salt is the sodium salt form of NADP (HY-113325). NADP is a coenzyme involved in cellular electron transfer reactions in biological metabolism, which is alternately oxidized (NADP+) and reduced (NADPH), and can maintain cellular redox homeostasis and regulate many biological events, including cellular metabolism. NADPH is a universal electron donor that provides reducing ability for synthetic metabolic reactions and redox balance. NADPH plays a multifunctional role in regulating inflammation, redox homeostasis, and synthetic metabolism processes[1][4].. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Sodium NADP. CAS No. 1184-16-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-F0002. | |
| NAD sodium | NAD (β-Nicotinamide Adenine Dinucleotide) sodium is an analogue of NAD. NAD sodium can be reduced to β-nicotinamide adenine dinucleotide (NADH) during coupling with reactions which oxidize organic substrates. NAD sodium can be converted to β-nicotinamide adenine dinucleotide (NADH) and passes to the inside of mitochondria that indirectly generates ATP [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: β-DPN sodium; β-NAD sodium; β-Nicotinamide Adenine Dinucleotide sodium. CAS No. 20111-18-6. Pack Sizes: 500 mg; 1 g. Product ID: HY-B0445A. | |
| Nafamostat mesylate | Nafamostat mesylate (FUT-175), an anticoagulant, is a synthetic serine protease inhibitor. Nafamostat mesylate has anticancer and antivirus effect. Nafamostat mesylate induce apoptosis by up-regulating the expression of tumor necrosis factor receptor-1 ( TNFR1 ). Nafamostat mesylate can be used in the development of the pathological thickening of the arterial wall [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FUT-175. CAS No. 82956-11-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-B0190A. | |
| Nafcillin sodium monohydrate | Nafcillin sodium monohydrate, an antibiotic, is a reversible inhibitor of β-lactamase. Nafcillin sodium monohydrate can be used for the research of staphylococcal infections [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 7177-50-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0555A. | |
| Nafetolol | Nafetolol (K 5407), specifically effective on cardiac (β1)-adrenoceptors, is an orally active β blocking agent, with a t 1/2 of ~ 2 h in dogs [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: K 5407 free base. CAS No. 42050-23-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-118770. | |
| Nafoxidine | Nafoxidine, a nonsteroidal estrogen antagonist, is shown to possess antitumor activity against breast cancer. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Nafoxidene. CAS No. 1845-11-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145716. | |
| Naftazone | Naftazone is a naphthoquinone derivative, it can be used for the research of venous insufciency. Naftazone protects blood vessels, increases venous tonicity and capillary resistance, and improves lymphatic and venous circulation [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 15687-37-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-108011. | |
| Naftidrofuryl oxalate | Naftidrofuryl oxalate (Nafronyl oxalate salt) is a drug used in the management of peripheral and cerebral vascular disorders as a vasodilator, enhance cellular oxidative capacity, and may also be a 5-HT2 receptor antagonist. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Nafronyl oxalate salt. CAS No. 3200-6-4. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B1107. | |
| Naftifine hydrochloride | Naftifine hydrochloride is an antibiotic. Naftifine hydrochloride has antifungal activity against dermatophytes, aspergilli, Sporothrix schenckii , and yeasts of the genus Candida. Naftifine hydrochloride can be used for the research of superficial dermatomycoses inhibition [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 65473-14-5. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-B0518A. | |
| Naftopidil | Naftopidil (KT-611) is is a selective alpha1-adrenoceptor antagonist, with K i s of 3.7 nM, 20 nM and 1.2 nM for the cloned human α 1a -, α 1b - and α 1d -adrenoceptor subtypes, respectively. Naftopidil has antiproliferative effects. Naftopidil can be used for the research of prostate hyperplasia [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KT-611; BM-15275. CAS No. 57149-07-2. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B0391. | |
| NAI-N3 | NAI-N3 is a RNA acylation reagent that enables RNA purification. NAI-N3 is a dual-function SHAPE (selective 2-hydroxyl acylation and profiling experiment) probe (RNA structure probe and enrichment)[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1612756-29-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103006. | |
| Naldemedine tosylate | Naldemedine (S-297995) tosylate is an orally active μ-opioid receptor antagonist (PAMORA) [1]. Naldemedine tosylate shows potent binding affinities ( K i =0.34, 0.43, 0.94 nM, respectively) and antagonist activities ( IC 50 =25.57, 7.09, 16.1 nM, respectively) for recombinant human μ-, δ-, and κ- opioid receptors [2]. Naldemedine can be used in opioid-induced constipation (OIC) research [2]. Naldemedine tosylate is predicted to bind to 3CL pro encoded by SARS-CoV2 genome [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: S-297995 tosylate. CAS No. 1345728-04-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-19627A. | |
| Nalidixic acid | Nalidixic acid, a quinolone antibiotic , is effective against both gram-positive and gram-negative bacteria. Nalidixic acid acts in a bacteriostatic manner in lower concentrations and is bactericidal in higher concentrations. Nalidixic acid inhibits a subunit of DNA gyrase and topoisomerase IV and reversibly blocks DNA replication in susceptible bacteria [1]. Uses: Scientific research. Group: Natural products. CAS No. 389-08-2. Pack Sizes: 10 mM * 1 mL; 5 g; 10 g. Product ID: HY-B0398. | |
| Nalidixic acid sodium salt | Nalidixic acid sodium salt, a quinolone antibiotic , is effective against both gram-positive and gram-negative bacteria. Nalidixic acid acts in a bacteriostatic manner in lower concentrations and is bactericidal in higher concentrations. Nalidixic acid inhibits a subunit of DNA gyrase and topoisomerase IV and reversibly blocks DNA replication in susceptible bacteria [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3374-5-8. Pack Sizes: 50 mg; 100 mg. Product ID: HY-B0398A. | |
| Nalidixic acid (Standard) | Nalidixic acid (Standard) is the analytical standard of Nalidixic acid. This product is intended for research and analytical applications. Nalidixic acid, a quinolone antibiotic , is effective against both gram-positive and gram-negative bacteria. Nalidixic acid acts in a bacteriostatic manner in lower concentrations and is bactericidal in higher concentrations. Nalidixic acid inhibits a subunit of DNA gyrase and topoisomerase IV and reversibly blocks DNA replication in susceptible bacteria [1]. Uses: Scientific research. Group: Natural products. CAS No. 389-08-2. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0398R. | |
| Nalmefene | Nalmefene is a long acting opioid ( MOR and DOR antagonist), and a partial KOR agonist. Nalmefene is used for opioid overdose and alcohol dependence [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 55096-26-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107744. | |
| Naloxegol oxalate | Naloxegol oxalate (NKTR-118 oxalate; AZ-13337019 oxalate) is a μ-opioid-receptor antagonist. Naloxegol oxalate inhibits opioid binding in μ-opioid receptors in the gastrointestinal tract and effective for alleviating opioid-induced constipation [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NKTR-118 oxalate; AZ-13337019 oxalate. CAS No. 1354744-91-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-A0118A. | |
| Naloxonazine dihydrochloride | Naloxonazine dihydrochloride is a specific μ-opioid receptor antagonist with an IC 50 of 5.4 nM. Naloxonazine dihydrochloride also shows anti-leishmanial activity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 880759-65-9. Pack Sizes: 5 mg. Product ID: HY-101011. | |
| Naloxone | Naloxone is an antagonist of Opioid receptor. Naloxone alleviates opioid-overdose-induced respiratory depression. Naloxone may cause pulmonary edema and cardiac arrhythmias [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 465-65-6. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-17417A. | |
| Naloxone benzoylhydrazone | Naloxone benzoylhydrazone (NalBzoH) is a mixed agonist/antagonist. Naloxone benzoylhydrazone is a prototypic κ3-opioid receptor agonist, and a partial agonist at the cloned μ and δ opioid receptors , and an antagonist at opioid-like NOP receptors. Naloxone benzoylhydrazone has potently analgesia effect [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NalBzoH. CAS No. 119630-94-3. Pack Sizes: 1 mg. Product ID: HY-107743. | |
| Naloxone hydrochloride | Naloxone hydrochloride is an antagonist of Opioid receptor. Naloxone hydrochloride alleviates opioid-overdose-induced respiratory depression. Naloxone hydrochloride may cause pulmonary edema and cardiac arrhythmias [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 357-08-4. Pack Sizes: 100 mg; 500 mg. Product ID: HY-17417. | |
| Naloxone methiodide | Naloxone methiodide is a peripherally restricted, nonselective, and competitive opioid receptor antagonist. Naloxone methiodide does not penetrate the blood-brain barrier [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 93302-47-7. Pack Sizes: 1 mg. Product ID: HY-137279. | |
| Nα-Benzoyl-L-arginine 4-nitroanilide hydrochloride | Nα-Benzoyl-L-arginine 4-nitroanilide (hydrochloride) is aarginine derivatives. Uses: Scientific research. Group: Peptides. CAS No. 21653-40-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-137529. | |
| Naltrexone | Naltrexone is an antagonist of Opioid receptor. Naltrexone inhibits cell proliferation in vivo. Naltrexone reduces tumor growth by interfering with cell signalling and modifying the immune system [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 16590-41-3. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-76711. | |
| Naltriben mesylate | Naltriben mesylate is a potent δ2-opioid receptor antagonist and a TRPM7 activator. Naltriben mesylate shows K i values of 0.013 nM, 19 nM and 152 nM for δ, μ and κ receptors, respectively. Naltriben mesylate enhances glioblastoma cell migration and invasion. Naltriben mesylate can be used in research into neurological diseases and cancer [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 122517-78-6. Pack Sizes: 5 mg. Product ID: HY-101302. | |
| NAMI-A | NAMI-A is a ruthenium-based agent characterized by selective activity against tumor metastasis, inhibiting adhesion and migration. Uses: Scientific research. Group: Signaling pathways. CAS No. 201653-76-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-19376. | |
| Namilumab | Namilumab (AMG203) is a human IgG1 monoclonal antibody that binds with high affinity to the GM-CSF ligand , potently neutralizing GM-CSF. Namilumab can be used for the research of rheumatoid arthritis [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: AMG-203; Anti-Human CSF2 Recombinant Antibody. CAS No. 1206681-39-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99307. | |
| Namodenoson | Namodenoson (CF-102) is a selective A3 adenosine receptor ( A3AR ) agonist ( K i =0.33 nM). Namodenoson displays 2500- and 1400-fold selectivity over A1 and A2A receptors respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CF-102; 2-Cl-IB-MECA. CAS No. 163042-96-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12365. | |
| Nampt activator-3 | NAMPT activator-3, a NAT derivative, is a NAMPT activator with an EC50 of 2.6 ?M and a KD of 132 nM. NAMPT activator-3 effectively protects cultured cells from FK866 (HY-50876)-mediated toxicity. NAMPT activator-3 exhibits strong neuroprotective efficacy in a chemotherapy-induced peripheral neuropathy (CIPN) mouse model without any overt toxicity[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2790481-63-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148948. | |
| Nampt-IN-1 | Nampt-IN-1 (LSN3154567) is a potent and selective NAMPT inhibitor. Nampt-IN-1 inhibits purified NAMPT with an IC50 of 3.1 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LSN3154567. CAS No. 1698878-14-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12971. | |
| Nampt-IN-15 | Nampt-IN-15 (Example 3) is an Nampt inhibitor. Nampt-IN-15 shows cytotoxicity against BxPC-3, HepG2, L540cy and MOLM-13, with IC 50 s of 38.5 nM, 8 nM, 8.5 nM, 7 nM respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2222981-61-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-402237. | |
| Nampt-IN-5 | Nampt-IN-5 is a potent nicotinamide phosphoribosyltransferase (NAMPT) inhibitor. Nampt-IN-5 also inhibits CYP3A4 activity and has cellular IC 50 s of 0.7 nM and 3.9 nM against A2780 and COR-L23, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2380013-17-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130606. | |
| NAN-190 hydrobromide | NAN-190 hydrobromide is a serotonin receptor 5-HT antagonist. NAN-190 is a selective antagonist of 5-HT 1A [1] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 115338-32-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-19818A. | |
| Nanaomycin A | Nanaomycin A is the first selective DNMT3B inhibitor with an IC50 of 500 nM. Nanaomycin A, a quinone antibiotics, reactivates silenced tumor suppressor genes in human cancer cells[1]. Nanaomycin A inhibits in vitro growth of the human malaria parasite Plasmodium falciparum with an IC80 value of 33.1 nM[2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 52934-83-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103397. | |
| Nanatinostat | Nanatinostat (CHR-3996) is a potent, class I selective and orally active histone deacetylase (HDAC) inhibitor with an IC 50 of 8 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CHR-3996. CAS No. 1256448-47-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13432. | |
| Nangibotide TFA | Nangibotide TFA (LR12 TFA) is a synthetic peptide and TREM-1 receptor inhibitor. Nangibotide TFA inhibits NF-?B and NLRP3 inflammasome activation and reduces the release of pro-inflammatory factors (such as IL-1?, IL-8). Nangibotide TFA inhibits Apoptosis. Nangibotide TFA reduces excessive inflammatory responses and protects tissues (liver, lung) from damage. Nangibotide TFA can be used in the researches for myocardial ischemia-reperfusion injury, septic shock, acute lung injury, osteoarthritis, and acute liver failure[1][2][3][4][5]. Uses: Scientific research. Group: Peptides. Alternative Names: LR12 TFA. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P3211A. | |
| Napabucasin | Napabucasin (BBI608) is a STAT3 inhibitor which blocks stem cell activity in cancer cells. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BBI608. CAS No. 83280-65-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-13919. | |
| Naphazoline hydrochloride | Naphazoline (Naphthazoline) hydrochloride is a potent α-adrenergic receptor agonist. Naphazoline hydrochloride reduces vascular hyperpermeability and promotes vasoconstriction. Naphazoline hydrochloride reduces the levels of inflammatory factors (TNF-α, IL-1β and IL-6), cytokines (IFN-γ and IL-4), IgE, GMCSF, and NGF. Naphazoline hydrochloride can be used for non-bacterial conjunctivitis research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Naphthazoline hydrochloride. CAS No. 550-99-2. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0446. | |
| Naphazoline nitrate | Naphazoline (Naphthazoline) nitrate is an α-adrenergic receptor agonist. Naphazoline nitrate reduces vascular hyperpermeability and promotes vasoconstriction. Naphazoline nitrate reduces the levels of inflammatory factors (TNF-α, IL-1β and IL-6), cytokines (IFN-γ and IL-4), IgE, GMCSF, and NGF. Naphazoline nitrate can be used for non-bacterial conjunctivitis research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Naphthazoline nitrate. CAS No. 5144-52-5. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-111326A. | |
| Naphthalene-2,3-Dicarboxaldehyde | Naphthalene-2,3-Dicarboxaldehyde (2,3-Naphthalenedicarboxaldehyde), a phthaldehyde derivative, is a fungal ASADH inhibitor (K i : 45 ?M). Naphthalene-2,3-Dicarboxaldehyde inhibits the growth of C. albicans CAF2-1 with IC 50 of 58.2 ?M and MIC of 12 ?g/mL [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 2,3-Naphthalenedicarboxaldehyde; Naphthalene-2,3-dialdehyde. CAS No. 7149-49-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-W016288. | |
| Naphthol AS-BI phosphate | Naphthol AS-BI phosphate is a substrate for acid and alkaline phosphatase and can be used in fluorescence assays. Naphthol AS-BI phosphate is a kind of biological materials or organic compounds that are widely used in life science research [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 1919-91-1. Pack Sizes: 50 mg; 100 mg. Product ID: HY-131475. | |
| Naphthol AS-MX phosphate | Naphthol AS-MX phosphate (NASTRp) is a small molecule inhibitor of the CREB (cyclic adenosine phosphate reaction element binding protein)- CBP (CREB binding protein) transcription factor complex. Naphthol AS-MX phosphate shows antitumor activity against lung cancer cells, inhibiting tumor cell proliferation ( IC 50 =3.701 μmol/L), colony formation, and anchored independent growth in soft AGAR. Naphthol AS-MX phosphate can be used in the study of KRAS mutated lung cancer, especially for KRAS mutated lung cancer with poor chemotherapy resistance and prognosis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NASTRp. CAS No. 1596-56-1. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-104067. | |
| Naphthol AS-TR phosphate disodium | Naphthol AS-TR Phosphate disodium is a water-soluble dye commonly used as an enzymatic substrate in various biochemical assays to detect alkaline phosphatase activity. Naphthol AS-TR Phosphate disodium has unique chemical properties that allow it to be hydrolyzed by alkaline phosphatase, forming a colored product that can be detected spectrophotometrically. This makes it a useful tool for monitoring enzyme activity in biological samples such as serum or urine. Uses: Scientific research. Group: Signaling pathways. CAS No. 4264-93-1. Pack Sizes: 100 mg. Product ID: HY-130767A. | |
| Naphthol green B | Naphthol green B is an iron-complex dye. Naphthol green B can be used in wool dyeing, silk dyeing and polyamide dyeing. Naphthol green B can be used to fabricate electrochemical sensor for the detection of H 2 O 2 [1] [2]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 19381-50-1. Pack Sizes: 25 g; 50 g; 100 g. Product ID: HY-W110905. | |
| Naphthoquine phosphate | Naphthoquine phosphate is a potent and orally active antimalarial agent. Naphthoquine phosphate has thorough killing function for various schizonts of plasmodia , including resistance of P. falciparum to Chloroquine [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 173531-58-3. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-17036. | |
| Naporafenib | Naporafenib (LXH254) is a potent, selective, orally active, type II BRAF and CRAF inhibitor, with IC 50 values of 0.072 and 0.21 nM against CRAF and BRAF, respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LXH254. CAS No. 1800398-38-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-112089. | |
| NAPQI | NAPQI is the toxic metabolite of Acetaminophen (HY-66005). NAPQI is also an inhibitor of enzymes in the vitamin K cycle. NAPQI is rapidly detoxified by glutathione (GSH), but in situations of GSH deficiency, excess NAPQI reacts with cysteine residues in proteins, causing cell death and toxicity in the liver [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 50700-49-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-W017464. | |
| Napropamide | Napropamide is an amide herbicide. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Napropamid. CAS No. 15299-99-7. Pack Sizes: 10 mM * 1 mL; 500 mg; 5 g. Product ID: HY-B1972. | |
| Napropamide (Standard) | Napropamide (Standard) is the analytical standard of Napropamide. This product is intended for research and analytical applications. Napropamide is an amide herbicide. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Napropamid (Standard). CAS No. 15299-99-7. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1972R. | |
| Naproxen | Naproxen is a COX-1 and COX-2 inhibitor with IC 50 s of 8.72 and 5.15 μM, respectively in cell assay. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (S)-Naproxen. CAS No. 22204-53-1. Pack Sizes: 10 mM * 1 mL; 500 mg; 5 g; 10 g. Product ID: HY-15030. | |
| (±)-Naproxen | (±)-Naproxen ((Rac)-Naproxen) is a racemate of Naproxen (HY-15030). Naproxen is a COX-1 and COX-2 inhibitor with IC 50 s of 8.72 and 5.15 μM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (Rac)-Naproxen; 2-(6-Methoxynaphthalen-2-yl)propanoic acid. CAS No. 23981-80-8. Pack Sizes: 10 mM * 1 mL; 1 g. Product ID: HY-15029. | |
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