MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Netoglitazone | Netoglitazone is a dual agonist of PPARα and PPARγ with antihyperglycemic activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MCC-555; Isaglitazone. CAS No. 161600-01-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100428. |  |
| Netropsin dihydrochloride | Netropsin dihydrochloride is a small-molecule MGB (minor-groove binder) and antibiotic, inhibits the catalytic activity of isolated topoisomerase and interferes with the stabilization of the cleavable complexes of topoisomerase II and I in nuclei. Netropsin dihydrochloride has antibacterial and antiviral activity [1] [4] [5]. Uses: Scientific research. Group: Natural products. CAS No. 18133-22-7. Pack Sizes: 1 mg. Product ID: HY-N6800A. | |
| Netupitant | Netupitant (CID-6451149) is a highly potent, selective and orally active neurokinin-1 (NK 1 ) receptor antagonist with a K i of 0.95 nM for hNK 1 in CHO cells. Netupitant has antiemetic affect [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CID 6451149. CAS No. 290297-26-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16346. | |
| Neuraminidase, Microorganism | Neuraminidase, Microorganism (Exo-α-sialidase) is an exosialidase, is often used in biochemical studies. Neuraminidase cleaves α-ketosidic linkage between the sialic (N-acetylneuraminic) acid and an adjacent sugar residue. Neuraminidase, derived from mucosal pathogens, is a virulence factor that modifies the host's response to infection [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Exo-α-sialidase. CAS No. 9001-67-6. Pack Sizes: 5 U; 10 U. Product ID: HY-P2988. | |
| Neurodazine | Neurodazine is a neurogenic inducer , serve as a promoter of neurogenesisin pluripotent cells. Neurodazine promotes neurogenesis by activating Wnt and Shh signaling pathways. [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 937807-66-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108439. | |
| Neurokinin A | Neurokinin A (Substance K), a peptide neurotransmitter of the tachykinin family, acts via the NK-2 receptor. Neurokinin A acts as a major mediator in human airway and gastrointestinal tissues [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Substance K; Neurokinin α; Neuromedin L. CAS No. 86933-74-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0197. | |
| Neurokinin A(4-10) TFA | Neurokinin A (4-10) TFA is a tachykinin NK2 receptor agonist[1]. Uses: Scientific research. Group: Peptides. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P0236A. | |
| Neurokinin A TFA | Neurokinin A TFA (Substance K TFA), a peptide neurotransmitter of the tachykinin family, acts via the NK-2 receptor. Neurokinin A acts as a major mediator in human airway and gastrointestinal tissues [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Substance K TFA; Neurokinin α TFA; Neuromedin L TFA; NKA TFA. CAS No. 2828433-19-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P0197A. | |
| Neurokinin B TFA | Neurokinin B TFA belongs to the tachykinin family of peptides. Neurokinin B binds a family of GPCRs-including neurokinin receptor 1 (NK1R), NK2R, and NK3R-to mediate their biological effect [1]. Uses: Scientific research. Group: Peptides. CAS No. 101536-55-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0242A. | |
| Neuromedin B | Neuromedin B (NMB) is a member of Bombesin (BN)-like peptide family in mammals. Uses: Scientific research. Group: Peptides. CAS No. 87096-84-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P0241. | |
| Neuromedin C (porcine) | Neuromedin C porcine (GRP, 18-27, porcine) is a bombesin-like neuropeptide that can be obtained from porcine spinal cord. Neuromedin C porcine exhibits a potent contractile activity on rat uterus in the characteristic manner of bombesin. Neuromedin C porcine has research potential for neurological-related diseases [1]. Uses: Scientific research. Group: Peptides. Alternative Names: GRP(18-27) (porcine). CAS No. 81608-30-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-103283. | |
| Neuromedin N | Neuromedin N is a potent modulator of dopamine D2 receptor agonist binding in rat neostriatal membranes. Uses: Scientific research. Group: Peptides. Alternative Names: Neuromedin N (rat, mouse, porcine, canine). CAS No. 92169-45-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-P0079. | |
| Neuromedin U-25 (porcine) | Neuromedin U-25 (porcine) is a uterus stimulating and hypertensive peptides [1]. Uses: Scientific research. Group: Peptides. CAS No. 98395-76-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P4682. | |
| Neuropeptide FF | Neuropeptide FF (NPFF), an octapeptide belonging to the RF-amide family of peptides, interacts with two distinct G-protein-coupled receptors, NPFF(1) and NPFF(2) and has wide variety of physiological functions in the brain including central cardiovascular and neuroendocrine regulation [1] [2]. Uses: Scientific research. Group: Peptides. Alternative Names: NPFF. CAS No. 99566-27-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1248. | |
| Neuropeptide SF (human) | Neuropeptide SF human augments paraventricular corticotrophin-releasing hormone (CRH) release and increases adrenocorticotropic hormone (ACTH) and corticosterone levels in the plasma. Neuropeptide SF human play a physiologic role in the regulation of such circadian functions as the activity of motor centers and the HPA axis, through the release of CRH [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Neuropeptide NPFF (human). CAS No. 192387-39-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1245. | |
| Neuropeptide S (human) | Neuropeptide S human, a neuropeptide, is a potent cognate neuropeptide S receptor (NPSR) agonist. Neuropeptide S human can be used for Alzheimer's disease (AD) research[1]. Uses: Scientific research. Group: Peptides. CAS No. 412938-67-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1389. | |
| Neuropeptide S (mouse) | Neuropeptide S (mouse) is a bioactive peptide. Neuropeptide S (mouse), as a neurotransmitter/neuromodulator of 20 amino acids, can be used for the research of arousal, anxiety, locomotion, feeding behaviors, memory and agent addiction [1]. Uses: Scientific research. Group: Peptides. CAS No. 412938-74-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1437. | |
| Neuropeptide W-23 (human) | Neuropeptide W-23 (human) (NPW-23), the active form of Neuropeptide W, is an endogenous agonist of NPBW1 (GPR7) and NPBW2 (GPR8) [1]. Uses: Scientific research. Group: Peptides. Alternative Names: NPW-23. CAS No. 383415-79-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1035. | |
| Neuropeptide Y (13-36), porcine | Neuropeptide Y (13-36), porcine is a selective neuropeptide Y 2 receptor agonist [1]. Uses: Scientific research. Group: Peptides. Alternative Names: NPY 13-36. CAS No. 113662-54-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1011. | |
| Neuropeptide Y(29-64) | Neuropeptide Y(29-64) is a 36 amino acid peptide, a fragment of Neuropeptide Y. Uses: Scientific research. Group: Peptides. CAS No. 303052-45-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1601. | |
| Neuropeptide Y (human,rat,mouse) | Neuropeptide Y (human,rat,mouse) is involved in Alzheimer's disease (AD) and protects rat cortical neurons against β-Amyloid toxicity. Uses: Scientific research. Group: Peptides. Alternative Names: Neuropeptide Y (29-64), amide. CAS No. 90880-35-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0198. | |
| Neurotensin | Neurotensin, a gut tridecapeptide, acts as a potent cellular mitogen for various colorectal and pancreatic cancers which possess high-affinity neurotensin receptors ( NTR ). Uses: Scientific research. Group: Peptides. CAS No. 39379-15-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P0234. | |
| Neurotensin(8-13) | Neurotensin (8-13) is an active fragment of Neurotensin. Neurotensin(8-13) results in a decrease in cell-surface NT1 receptors (NTR1) density. Uses: Scientific research. Group: Peptides. CAS No. 60482-95-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P0251. | |
| Neutral protease I | Neutral protease I (Dispase I) is a rapid, effective, gentle and neutral protease that can separate intact epidermis from the dermis. Neutral protease I can also separate intact epithelial sheets in culture from the substratum. Neutral protease I preserves the viability of the epithelial cells while cleaving the basement membrane zone region. Neutral protease I can also be used to prevent clumping in suspension cultures. Neutral protease I cleaves fibronectin and type IV collagen, but not laminin, type V collagen, serum albumin, or transferrin [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Dispase I. CAS No. 42613-33-2. Pack Sizes: 1 mg. Product ID: HY-131577A. | |
| Neutral Red | Neutral Red, a nitrogenous pH-indicator with a pK i of 6.8, is an indicator for the internal acidification of thylakoids. Neutral Red stains lysosomes red [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 553-24-2. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-D0166. | |
| Neutrophil elastase inhibitor 1 | Neutrophil elastase inhibitor 1 (Compound 5b) is a competitive, pseudoirreversible inhibitor for neutrophil elastase with an IC 50 of 7 nM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1448314-31-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-118177. | |
| Nevanimibe hydrochloride | Nevanimibe hydrochloride (PD-132301 hydrochloride) is an orally active and selective acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) inhibitor with an EC50 of 9 nM. Nevanimibe hydrochloride inhibits ACAT2 with an EC50 of 368 nM. Nevanimibe hydrochloride induces cell apoptosis and has the potential for adrenocortical cancer[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PD-132301 hydrochloride; ATR101 hydrochloride. CAS No. 133825-81-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100399A. | |
| Nevirapine | Nevirapine is a non-nucleoside inhibitor of HIV-1 reverse transcriptase used to treat and prevent HIV/AIDS; with a K i of 270 μM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BI-RG 587; NSC 641530; NVP. CAS No. 129618-40-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10570. | |
| Nexinhib20 | Nexinhib20 is an inhibitor that targets the interactions of Rab27a-JFC1 (IC50: 2.6 ?M) and Rac-1-GTP. Nexinhib20 can inhibit neutrophil exocytosis, adhesion, and ?2 integrin activation, and has anti-inflammatory activity. Nexinhib20 can be used in the research of diseases such as systemic inflammation and myocardial ischemia-reperfusion injury[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 331949-35-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125792. | |
| Nexturastat A | Nexturastat A is a potent, selective HDAC6 inhibitor. Nexturastat A has inhibitory for HDAC6 with an IC50 of 5 nM. Nexturastat A can be used for the research of multiple myeloma (MM)[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1403783-31-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16699. | |
| NF110 | NF110 is a P2X 3 receptor antagonist ( K i=36 nM) and inactive toward P2Y receptors stably expressed (IC 50 s > 10 M). NF110 blocks alphabeta-methylene-ATP-induced currents (IC 50 = 527 nM) in rat dorsal root ganglia neurons [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 111150-22-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-108671. | |
| NF279 | NF279 is a potent selective and reversible P2X1 receptor antagonist, with an IC 50 of 19 nM. NF279 displays good selectivity over P2X2, P2X3 (IC 50=1.62 μM), P2X4 (IC 50 >300 μM). NF279 is a dual HIV-1 coreceptor inhibitor that interferes with the functional engagement of CCR5 and CXCR4 by Env [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 202983-32-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-D0976. | |
| NF449 octasodium | NF449 octasodium is a highly potent P2X1 receptor antagonist, with IC50s of 0.28, 0.69, and 120 nM for rP2X1, rP2X1+5, P2X2+3, respectively. NF449 octasodium is a Gs?-selective G Protein antagonist. NF449 octasodium suppresses the rate of GTP[?S] binding to Gs?-s, inhibits the stimulation of adenylyl cyclase activity, and blocks the coupling of ?-adrenergic receptors to Gs[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 627034-85-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112461A. | |
| NF-56-EJ40 | NF-56-EJ40 is a potent, high-affinity, and highly selective human SUCNR1 (GPR91) antagonist with an IC50 of 25 nM and a Ki of 33 nM, and shows almost no activity towards rat SUCNR1. NF-56-EJ40 has high affinity for humanized rat SUCNR1 with a Ki value of 17.4 nM[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2380230-73-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130246. | |
| NF764 | NF764 is a potent ?-catenin (CTNNB1) degrader. NF764 reduces CTNNB1 protein levels in a proteasome-dependent manner. NF764 can be used in the study of cancer[1]. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 1 mg; 5 mg. Product ID: HY-161719. | |
| NFAT Inhibitor-1 | NFAT Inhibitor (VIVIT peptide) is an inhibitor of nuclear factor of activated Tcells (NFAT) that selectively inhibits calcineurin-mediated dephosphorylation of NFAT[1][2]. Uses: Scientific research. Group: Peptides. Alternative Names: VIVIT peptide. CAS No. 249537-73-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P1026. | |
| NF-κB-IN-11 | NF-κB-IN-11 (Compound 3i) is a NF-κB inhibitor. NF-κB-IN-11 inhibits TNF-α induced activation of NF-κB pathway, and inhibits nuclear translocation of NF-κB. NF-κB-IN-11 down-regulates the expression levels of phosphor-IKK, IκBα, and NF-κB p65. NF-κB-IN-11 has anti-inflammatory activity, and alleviates dextran sulfate sodium-induced colitis in mice. NF-κB-IN-11 (p.o.) shows a MTD more than 1852 mg/kg in mice acute toxicity assay [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2768833-35-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-155998. | |
| N-Formylcytisine | N-Formylcytisine is a cytisine-type alkaloid from the stem bark of Maackia amurensis [1]. Uses: Scientific research. Group: Natural products. CAS No. 53007-06-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N7625. | |
| N-Formylglycine | N-Formylglycine is an endogenous metabolite. Uses: Scientific research. Group: Natural products. CAS No. 2491-15-8. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-128735. | |
| N-Formyl-Met-Leu-Phe | N-Formyl-Met-Leu-Phe (fMLP; N-Formyl-MLF) is a chemotactic peptide and a specific ligand of N-formyl peptide receptor (FPR). N-Formyl-Met-Leu-Ph is reported to inhibit TNF-alpha secretion. Uses: Scientific research. Group: Peptides. Alternative Names: fMLP; N-Formyl-MLF. CAS No. 59880-97-6. Pack Sizes: 5 mg; 10 mg; 50 mg. Product ID: HY-P0224. | |
| N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys | N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys TFA (For-Nle-Leu-Phe-Nle-Tyr-Lys-OH TFA) is a formyl peptide receptor (FPR) agonist [1]. Uses: Scientific research. Group: Peptides. Alternative Names: For-Nle-Leu-Phe-Nle-Tyr-Lys-OH. CAS No. 71901-21-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P1591. | |
| NG25 | NG25 is a potent dual TAK1 and MAP4K2 inhibitor, with IC50s of 149 nM and 21.7 nM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1315355-93-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-15434. | |
| NG-497 | NG-497 is a selective human adipose triglyceride lipase (ATGL) inhibitor that targets the enzymatically active patatin-like domain of human ATGL. NG-497 has potential value for tumor research[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2598242-66-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148756. | |
| NGI-1 | NGI-1 (ML414) is a potent oligosaccharyltransferase (OST) inhibitor, directly targeting and blocking the function of the OST catalytic subunits STT3A and STT3B[1]. NGI-1 is a cell permeable inhibitor and can effectively reduce virus infectivity without affecting cell viability[2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ML414. CAS No. 790702-57-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-117383. | |
| N-Glycolylneuraminic acid | N-Glycolylneuraminic acid is a nonhuman sialic acid molecule synthesized in pigs but not in humans. N-Glycolylneuraminic acid works as a decoy receptor of N-Glycolylneuraminic acid-binding influenza A viruses (IAVs) [1]. Uses: Scientific research. Group: Natural products. Alternative Names: NeuGc; GcNeu. CAS No. 1113-83-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-128965. | |
| NGM-120 | NGM-120 is a CHO-expressed human antibody that targets GFRAL. NGM-120 contains huIgG1 heavy chain and huκ light chain, with a predicted molecular weight (MW) of 145.7 kDa. The isotype control for NGM-120 can refer to Human IgG1 kappa, Isotype Control (HY-P99001). Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2387417-06-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990635. | |
| NG-nitro-L-arginine | NG-nitro-L-arginine (Nω-nitro-L-arginine) is a NO Synthase inhibitor, with K i s of 0.61 μM (nNOS), 4.28 μM (iNOS), 0.72 μM (eNOS) respectively. NG-nitro-L-arginine inhibits endothelium-derived relaxing factor ( EDRF ) formation and release. NG-nitro-L-arginine inhibits portal-systemic shunting in portal-hypertensive rats, and increases blood pressure [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Nω-nitro-L-arginine; L-NOARG; L-NG-Nitroarginine. CAS No. 2149-70-4. Pack Sizes: 10 mM * 1 mL; 25 g. Product ID: HY-12115. | |
| NH125 | NH125 is a potent and selective inhibitor of eukaryotic elongation factor 2 kinase (eEF-2K/CaMKIII) , also can induce eEF2 phosphorylation, with an IC 50 of 60 nM for eEF-2K [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 278603-08-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100576. | |
| (NH2)2bpy | (NH2)2bpy (4,4'-Diamino-2,2'-bipyridine) is an organic compound commonly used as a catalyst and complexing reagent. It can form complexes with other metal ions or organic molecules, and can play a catalytic role in some organic synthesis reactions. In addition, this compound is also widely used in some chemical analysis and detection methods, such as in biological analysis and electrochemical analysis. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: 4,4'-Diamino-2,2'-bipyridine. CAS No. 18511-69-8. Pack Sizes: 500 mg; 1 g. Product ID: HY-W004547. | |
| NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT hydrochloride | NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT (compound I) hydrochloride is a topoisomerase I inhibitor, which can be delivered to cells through conjugated antibody targeting, and has good ADC activity in vivo and in vitro[1]. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148819A. | |
| NH2-PEG3 | NH2-PEG3 (PROTAC Linker 35) is a PROTAC linker, which belongs to a polyethylene glycol (PEG) linker. NH2-PEG3 (PROTAC Linker 35) can be used in the synthesis of the PROTAC (β-NF-JQ1) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PROTAC Linker 35. CAS No. 6338-55-2. Pack Sizes: 1 g; 5 g. Product ID: HY-W007545. | |
| NH2-PEG5-C2-NH-Boc | NH2-PEG5-C2-NH-Boc (PROTAC Linker 17) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PROTAC Linker 17. CAS No. 189209-27-6. Pack Sizes: 100 mg; 500 mg; 1 g. Product ID: HY-W022240. | |
| NH2-PEG8-acid | NH2-PEG8-acid is a non-cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. NH2-PEG8-acid also is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 756526-04-2. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-W019798. | |
| NH2-UAMC1110 TFA | NH2-UAMC1110 TFA is a UAMC1110 (HY-100684) derivative that can be used in the synthesis of FAPI-QS. UAMC1110 is a fibroblast activation protein (FAP) inhibitor. FAPI-QS is a chelating agent that can be used to synthesize high tumor selectivity and high dose radiotracers for the diagnosis and treatment of tumors[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2990021-73-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-153552A. | |
| NH-3 | NH-3 is an orally active, reversible thyroid hormone receptor (THR) antagonist with an IC 50 of 55 nM. NH-3, a derivative of the selective thyromi-metic GC-1, inhibits binding of thyroid hormones to their receptor and that inhibits cofactor recruitment [1] [2] [3]. NH-3 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 447415-26-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141513. | |
| NHC-triphosphate tetraammonium | NHC-triphosphate tetraammonium is an active phosphorylated intracellular metabolite of ?-d-N4-Hydroxycytidine (NHC) (HY-125033) as a triphosphate form[1]. NHC-triphosphate tetraammonium is a weak alternative substrate for the viral polymerase and can be incorporated into HCV replicon RNA[1][2]. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-135867E. | |
| N-hexadecane-d34 | N-hexadecane-d 34 is the deuterium labeled N-hexadecane[1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 15716-08-2. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-W099580S1. | |
| N-Hexadecyltrimethylammonium hexafluorophosphate | N-hexadecyltrimethyl Ammonium hexafluorophosphate is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 101079-29-2. Pack Sizes: 1 g; 5 g. Product ID: HY-W099577. | |
| N-Hexanoyl-DL-homoserine lactone | N-Hexanoyl-DL-homoserine lactone is a bacterial quorum sensing molecule produced in the rhizosphere. N-Hexanoyl-DL-homoserine lactone, a bacterial quorum sensing signal, induces transcriptional changes in Arabidopsis and may contribute to tuning plant growth to the microbial composition of the rhizosphere [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 106983-28-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W045071. | |
| N-Hexanoyl-L-homoserine lactone | N-Hexanoyl-L-homoserine lactone is a short-chained N-acyl homoserine lactone (AHL). N-hexanoyl-L-homoserine lactone is also a mediator of bacterial quorum-sensing regulation. N-hexanoyl-L-homoserine lactone promotes lipid accumulation in algae. AHL is an intercellular communication signal molecule in the quorum sensing system of Gram-negative bacteria and a medium for mediating information exchange between eukaryotic plants and prokaryotic bacteria. AHL can affect bacteria activities, such as biofilm formation, pigment synthesis, and antibiotic synthesis [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 147852-83-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-133685. | |
| NHSF | NHSF is a protein cross-linking agent [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2292112-27-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-159008. | |
| NHS-SS-biotin | NHS-SS-biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 122266-55-1. Pack Sizes: 25 mg. Product ID: HY-140129. | |
| N-Hydroxyphthalimide | N-Hydroxyphthalimide is a kind of biological materials or organic compounds that are widely used in life science research [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 524-38-9. Pack Sizes: 50 g; 100 g. Product ID: HY-Y0396. | |
| N-Hydroxypipecolic acid | N-Hydroxypipecolic acid (1-Hydroxy-2-piperidinecarboxylic acid), a plant metabolite and a systemic acquired resistance (SAR) regulator, orchestrates SAR establishment in concert with the immune signal salicylic acid. N-Hydroxypipecolic acid accumulates systemically in the plant foliage in response to pathogen attack. N-Hydroxypipecolic acid induces SAR to bacterial and oomycete infection[1][2][3]. Uses: Scientific research. Group: Natural products. Alternative Names: 1-Hydroxy-2-piperidinecarboxylic acid; NHP. CAS No. 115819-92-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-N7378. | |
| N-Hydroxysuccinimide | N-Hydroxysuccinimide (HOSu; 1-Hydroxy-2,5-pyrrolidinedione) is an activated ester commonly used in bioconjugation technologies such as protein labeling with fluorescent dyes and enzymes, chromatography supports, beads, nanoparticles, and microarrays Surface activation of glass slides, and chemically synthesized peptides [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: HOSu; 1-Hydroxy-2,5-pyrrolidinedione. CAS No. 6066-82-6. Pack Sizes: 5 g; 10 g. Product ID: HY-Y0623. | |
| N-Hydroxysulfosuccinimide sodium | N-Hydroxysulfosuccinimide (sodium) is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 106627-54-7. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-W002213. | |
| NI-42 | NI-42 (compound 13-d), a structurally orthogonal chemical probe for the BRPFs, is a biased, potent inhibitor of the BRD of the BRPFs ( IC 50 s of BRPF1/2/3=7.9/48/260 nM; K d s of BRPF1/2/3=40/210/940 nM) with excellent selectivity over nonclass IV BRD proteins [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1884640-99-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101121. | |
| NI-57 | NI-57 is an inhibitor of bromodomain and plant homeodomain finger-containing ( BRPF ) famlily of proteins, with IC 50 s of 3.1, 46 and 140 nM for BRPF1, BRPF2 (BRD1) and BRPF3, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1883548-89-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19537. | |
| Niacin | Niacin (Vitamin B3) is an orally active water-soluble B3 vitamin that is an essential nutrient for humans. Niacin (Vitamin B3) plays a key role in energy metabolism, cell signaling cascades regulating gene expression and apoptosis. Niacin (Vitamin B3) is also used in the study of cardiovascular diseases [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Nicotinic acid; Vitamin B3. CAS No. 59-67-6. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0143. | |
| Niacin (standard) | Niacin (Standard) is the analytical standard of Niacin. This product is intended for research and analytical applications. Niacin (Vitamin B3) is an orally active water-soluble B3 vitamin that is an essential nutrient for humans. Niacin (Vitamin B3) plays a key role in energy metabolism, cell signaling cascades regulating gene expression and apoptosis. Niacin (Vitamin B3) is also used in the study of cardiovascular diseases [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Nicotinic acid (standard); Vitamin B3 (standard). CAS No. 59-67-6. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-B0143R. | |
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