MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Ritalinic acid | Ritalinic acid (Ritalinate) is the main inactive urinary metabolite of Methylphenidate. Methylphenidate has the potential for attention-deficit hyperactivity disorder and narcolepsy research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ritalinate. CAS No. 19395-41-6. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-W042214. |  |
| Ritanserin | Ritanserin (R 55667) is a highly potent, relatively selective, orally active, long acting antagonist of 5-HT 2 receptor , with an IC 50 of 0.9 nM, less active on Histamine H 1 , Dopamine D 2 , Adrenergic α 1 , Adrenergic α 2 receptors [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R 55667. CAS No. 87051-43-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10791. | |
| Ritlecitinib | Ritlecitinib (PF-06651600) is an orally active and selective JAK3 inhibitor with an IC 50 of 33.1 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PF-06651600. CAS No. 1792180-81-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-100754. | |
| Ritlecitinib tosylate | Ritlecitinib tosylate is an orally active and selective JAK3 inhibitor with an IC 50 of 33.1 nM. Ritlecitinib tosylate is used for inflammatory and autoimmune diseases research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PF-06651600 tosylate. CAS No. 2192215-81-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100754C. | |
| Ritodrine hydrochloride | Ritodrine (DU21220) hydrochloride is a potent and orally active β-adrenergic agonist. Ritodrine hydrochloride decreases preterm delivery and uterine contraction. Ritodrine hydrochloride has the potential for the research of preterm labor [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DU21220 hydrochloride. CAS No. 23239-51-2. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0452. | |
| Ritolukast | Ritolukast (Wy-48252) is an orally active aerosol leukotriene ( LTD 4 /E 4 ) receptor antagonist. Ritolukast can be used to inhibit the bronchoconstriction caused by aerosol LTD 4 in guinea pigs, with an ID 50 of 0.5mg/kg [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Wy-48252. CAS No. 111974-60-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-156978. | |
| Ritonavir | Ritonavir (ABT 538) is an inhibitor of HIV protease used to treat HIV infection and AIDS. Ritonavir is also a SARS-CoV 3CL pro inhibitor with an IC 50 of 1.61 μM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABT 538; RTV. CAS No. 155213-67-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-90001. | |
| Ritonavir metabolite | Ritonavir metabolite is a metabolite of Ritonavir, which is a HIV protease inhibitor. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Desthiazolylmethyloxycarbonyl Ritonavir. CAS No. 176655-55-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-G0009. | |
| Rituximab | Rituximab is an anti-CD20 chimeric monoclonal antibody used for research of certain autoimmune diseases and cancer. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-Human CD20 type I, Chimeric Antibody. CAS No. 174722-31-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P9913. | |
| Rituximab (anti-CD20) | Rituximab (anti-CD20) is an anti-CD20 chimeric monoclonal antibody used to treat certain autoimmune diseases and types of cancer [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 174722-31-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P9913A. | |
| Rivaroxaban | Rivaroxaban (BAY 59-7939) is a highly potent, selective and direct Factor Xa ( FXa ) inhibitor, achieving a strong gain in anti-FXa potency ( IC 50 0.7 nM; K i 0.4 nM) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 59-7939. CAS No. 366789-02-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-50903. | |
| Rivaroxaban EP Impurity I | Rivaroxaban EP Impurity I (Imp I) is the impurity reference for Rivaroxaban EP [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1151893-81-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-I0454. | |
| Rivastigmine | Rivastigmine (ENA 713 free base) is an orally active and potent cholinesterase (ChE) inhibitor and inhibits butyrylcholinesterase (BChE) and acetylcholinesteras (AChE) with IC 50 s of 0.037 μM , 4.15 μM, respectively. Rivastigmine can pass the blood brain barrier (BBB). Rivastigmine is a parasympathomimetic or cholinergic agent used for the research of mild to moderate dementia of the Alzheimer's type and dementia due to Parkinson's disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ENA 713 free base; SDZ-ENA 713 free base. CAS No. 123441-03-2. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-17368. | |
| Rivastigmine metabolite | Rivastigmine metabolite (NAP 226-90) is an acetylcholinesterase ( AChE ) inhibitor which is produced in kidney. Rivastigmine metabolite is promising for research of Alzheimers Disease [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NAP 226-90. CAS No. 139306-10-8. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-W020576. | |
| Rivastigmine tartrate | Rivastigmine tartrate (ENA 713; SDZ-ENA 713) is an orally active and potent cholinesterase (ChE) inhibitor and inhibits butyrylcholinesterase (BChE) and acetylcholinesteras (AChE) with IC 50 s of 0.037 μM, 4.15 μM, respectively. Rivastigmine tartrate can pass the blood brain barrier (BBB). Rivastigmine tartrate is a parasympathomimetic or cholinergic agent used for the research of mild to moderate dementia of the Alzheimer's type and dementia due to Parkinson's disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ENA 713; SDZ-ENA 713. CAS No. 129101-54-8. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg. Product ID: HY-11017. | |
| Rivoglitazone | Rivoglitazone is a thiazolidinedione-derivative PPARγ agonist for the research of type 2 diabetes mellitus. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R-106056. CAS No. 185428-18-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-106181. | |
| Rizatriptan benzoate | Rizatriptan benzoate is the agonist for 5-HT 1B and 5-HT 1D. Rizatriptan benzoate has a peripheral vasoconstrictive effect, penetrates the intact blood-brain barrier, and inhibits pain neurotransmission in the central nervous system [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK 462. CAS No. 145202-66-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-B0206. | |
| RK-33 | RK-33 is an RNA helicase inhibitor against DDX3, and inhibits its helicase activity. Uses: Scientific research. Group: Signaling pathways. CAS No. 1070773-09-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100455. | |
| RK-682 | RK-682 is the inhibitor for protein tyrosine phosphatase ( PTPase ), heparanase , phospholipase A2 and HIV-1 protease. RK-682 inhibits the dephosphorylation of CD45 ( IC 50 is 54 μM) and VHR ( IC 50 is 2.0 μM), and thereby inhibits the ERK signaling pathway. RK-682 inhibits the cell viability of cancer cell MGH-U3, T24 and UROtsa with IC 50 s of 78.2, 43.2 and 145 nM, respectively, arrests the cell cycle at G1/S phase, inhibits the cell migration and autophagy in MGH-U3 and T24 [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 150627-37-5. Pack Sizes: 200 μg. Product ID: HY-135564A. | |
| RKI-1447 | RKI-1447 is a potent small molecule inhibitor of ROCK1 and ROCK2 with IC 50 values of 14.5 nM and 6.2 nM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1342278-01-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15755. | |
| RKI-1447 dihydrochloride | RKI 1447 dihydrochloride is a potent and selective ROCK inhibitor with IC 50 s of 14.5 and 6.2 nM for ROCK1 and ROCK2 , respectively [1]. RKI 1447 dihydrochloride suppresses colorectal carcinoma cell growth and promotes apoptosis [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1782109-09-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110339. | |
| RL71 | RL71 is a curcuminoid anticancer agent that exhibits potent cytotoxicity against a variety of ER-negative breast cancer cells. RL71 (1 μM) induces cell cycle arrest in the G2/M phase and induces apoptosis in SKBr3 cells. RL7 also decreases HER2/neu phosphorylation and increases p27. RL71 also significantly reduced the phosphorylation of Akt and transiently increased the stress kinases JNK1/2 and p38 MAPK. Furthermore, RL71 exhibited anti-angiogenic potential in vitro, inhibiting the migration of HUVEC cells and the ability of these cells to form tubular networks [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1195795-93-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-121605. | |
| RLY-2608 | RLY-2608 is an orally active first-in-class allosteric mutant-selective inhibitor of PI3Ka with anti-tumor activity. RLY-2608 inhibits tumor growth in PIK3CA-mutant xenograft mice models with minimal impact on insulin [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2733573-94-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153306. | |
| RMC-5552 | RMC-5552 is a potent and selective mTORC1 inhibitor. RMC-5552 inhibits phosphorylation of mTORC1 pS6K and p4EBP1 with IC 50 s of 0.14 nM and 0.48 nM, respectively. RMC-5552 shows much lower pAKT inhibition (IC 50 of 19 nM), resulting in mTORC1/mTORC2 selectivity approaching 40-fold. RMC-5552 has anti-cancer activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2382768-62-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-132168. | |
| RMC-6236 | RMC-6236 (Compound A122) is a potent RAS(ON) MULTI inhibitor. RMC-6236 can be used in lung adenocarcinoma research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RAS-IN-2. CAS No. 2765081-21-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148439. | |
| RMC-7977 | RMC-7977 is an orally active triple-complex RAS inhibitor that can simultaneously bind to cyclophilin A (CYPA) (K d = 195 nM) and KRAS (G12V) (K d = 292 μM). It exhibits broad-spectrum inhibitory activity against KRAS, NRAS, and HRAS proteins and their various wild-type and mutant variants. RMC-7977 induces apoptosis by inhibiting the phosphorylation of ERK , CRAF , and RSK , as well as increasing PARP cleavage. This leads to tumor regression, reduces resistance in KRAS G12C cancer models, and demonstrates good tolerability across various RAS cancer models [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2765082-12-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-156498. | |
| (R)-Methanandamide | (R)-Methanandamide (AM-356), an analog of the endocannabinoid ligand Anandamide, is a potent CB1 agonist with a K i of 20 nM. (R)-Methanandamide also activates vanilloid (TRPV1) receptors [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AM-356. CAS No. 157182-49-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-101389. | |
| (R)-Mirtazapine | (R)-Mirtazapine ((R)-Org3770) is a R(-)-enantiomer of Mirtazapine with antinociceptive properties in an animal model of acute thermal nociception. (R)-Mirtazapine is a 5-HT 3 receptor antagonist. (R)-Mirtazapine is mainly metabolized by CYP3A4 [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (R)-Org3770; (R)-6-Azamianserin. CAS No. 61364-37-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-B0352B. | |
| RN-1 dihydrochloride | RN-1 dihydrochloride is a potent, brain-penetrant, irreversible and selective lysine-specific demethylase 1 (LSD1) inhibitor with an IC 50 of 70 nM. RN-1 dihydrochloride exhibits selectivity for LSD1 over MAO-A and MAO-B with IC 50 values of 0.51 μM and 2.785 μM respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1781835-13-9. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-110130. | |
| RN-9893 | RN-9893 is a potent and selective TRPV4 receptor antagonist with IC 50 values of 320, 420 and 660 nM for mouse, human and rat channels, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1803003-68-0. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-110270. | |
| RNase A, Bovine pancreas | RNase A, Bovine pancreas (Ribonuclease A) cleaves the 3' end of RNA to pyrimidine and actively cleaves RNA at each pyrimidine residue. RNase A, bovine pancreas catalyzes the hydrolysis of single-stranded RNA in the absence of metal ions or cofactors [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ribonuclease A; EC 4.6.1.18; RNase A. CAS No. 9001-99-4. Pack Sizes: 25 mg; 50 mg. Product ID: HY-129046. | |
| (R)-(-)-N-Boc-3-pyrrolidinol | (R)-(-)-Boc-3-pyrrolidinol is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 109431-87-0. Pack Sizes: 25 g; 50 g. Product ID: HY-W001294. | |
| RNPA1000 | RNPA1000, an antibiotic , is a potent RnpA inhibitor and inhibits RnpA-mediated cellular RNA degradation. RNPA1000 inhibits tRNA maturation with an IC 50 of 175 μM. RNPA1000 displays broad-spectrum antimicrobial activities and inhibits staphylococcal and all Gram-positive bacterial pathogens activity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 359600-10-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-12824. | |
| Ro15-4513 | Ro15-4513, imidazobenzodiazepinone derivative, is a partial inverse agonist of benzodiazepine receptor (BZR) [1]. Ro15-4513 is a potent ethanol antagonist [2]. Ro15-4513 has anti-anxiety effect [3]. Ro15-4513 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 91917-65-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103476. | |
| Ro 25-6981 | Ro 25-6981 is a potent, selective and activity-dependent NR2B subunit specific NMDA receptor antagonist. Ro 25-6981 shows anticonvulsant and anti-parkinsonian activity. Ro 25-6981 has the potential for the research of parkinson's disease (PD) [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 169274-78-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-13993. | |
| Ro 25-6981 Maleate | Ro 25-6981 Maleate is a potent, selective and activity-dependent NR2B subunit specific NMDA receptor antagonist. Ro 25-6981 Maleat shows anticonvulsant and anti-parkinsonian activity. Ro 25-6981 Maleate has the potential for the research of parkinson's disease (PD) [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1312991-76-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13993A. | |
| RO-3 | RO-3 is a potent, CNS-penetrant, and orally active P2X 3 and P2X 2/3 antagonist with pIC 50 s of 5.9 and 7.0 for human homomultimeric P2X 3 and heteromultimeric P2X 2/3 receptors, respectively. RO-3 shows selectivity for P2X 3 and P2X 2/3 over all other functional homomultimeric P2X receptors (IC 50 >10 μM at P2X 1,2,4,5,7 ) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1026582-88-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-19978. | |
| RO3201195 | RO3201195 (compound 1) is an inhibitor of p38 MAPK. RO3201195 inhibits WS cell proliferation with IC 50 value of 190 nM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 249937-52-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-118612. | |
| RO3244794 | RO3244794 is a potent and selective IP (prostacyclin) receptor antagonist, with a pK i of 7.7 and 6.9 in human platelet and recombinant IP receptor system, respectively. RO3244794 exhibits analgesic and anti-inflammatory potential [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 361457-01-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-164580. | |
| Ro 363 hydrochloride | Ro 363 hydrochloride, an effective inotropic stimulant, is a potent and highly selective β1-adrenoceptor agonist. Ro 363 hydrochloride is a cardiovascular modulator that reduces diastolic blood pressure and pronounces increases in myocardial contractility [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 250580-70-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-123268A. | |
| Ro 48-8071 fumarate | Ro 48-8071 fumarate is an inhibitor of OSC (Oxidosqualene cyclase) with IC 50 of appr 6.5 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 189197-69-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18630A. | |
| RO5454948 | Mirk-IN-1 (Dyrk1B/A-IN-1) is a highly efficient and selective inhibitor of Dyrk1B and Dyrk1A, with IC50 values of 68 and 22nM respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Mirk-IN-1; Dyrk1B/A-IN-1. CAS No. 1386979-55-0. Pack Sizes: 5 mg; 10 mg; 50 mg. Product ID: HY-12838. | |
| Ro60-0175 | Ro60-0175 is a potent and selective agonist of 5-HT 2C receptor. Ro60-0175 reduces self-administration [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 169675-08-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123838. | |
| Ro60-0175 fumarate | Ro60-0175 fumarate is a potent and selective agonist of 5-HT 2C receptor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 169675-09-6. Pack Sizes: 10 mM * 1 mL; 5 mg. Product ID: HY-103140. | |
| Ro 64-6198 | Ro 64-6198 is a potent, selective, nonpeptide, high-affinity, high cellular permeability and brain penetration N/OFQ receptor (NOP) agonist with an EC 50 value of 25.6 nM. Ro 64-6198 is at least 100 times more selective for the NOP receptor over the classic opioid receptors. Ro 64-6198 can be used for stress and anxiety, addiction, neuropathic pain, cough, and anorexia [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 280783-56-4. Pack Sizes: 10 mM * 1 mL; 5 mg. Product ID: HY-12844. | |
| Ro 67-7476 | Ro 67-7476 is a potent positive allosteric modulator of mGluR 1 and potentiates glutamate-induced calcium release in HEK293 cells expressing rat mGluR1a with an EC 50 of 60.1 nM [1] [2]. Ro 67-7476 is a potent P-ERK1/2 agonist and activates ERK1/2 phosphorylation in the absence of exogenously added glutamate ( EC 50 =163.3 nM) [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 298690-60-5. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100403. | |
| Robatumumab | Robatumumab (Sch 717454) is an anti-human IGF-1R ( insulin-like growth factor receptor-1 ) antibody. Robatumumab shows anti-tumor activity and anti-proliferative activity to cancer cells. Robatumumab can be used in osteosarcoma and Ewing sarcoma research [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Sch 717454; 19D12. CAS No. 934235-44-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99218. | |
| Robenacoxib | Robenacoxib is a nonsteroidal anti-inflammatory and analgesic agent. Robenacoxib is a selective COX-2 inhibitor [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 220991-32-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-118078. | |
| Robenidine hydrochloride | Robenidine hydrochloride is an anticoccidial agent which is also active against MRSA and VRE with MIC 50 s of 8.1 and 4.7 μM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 25875-50-7. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B2157. | |
| Roblitinib | Roblitinib (FGF-401) is an orally active and highly selective FGFR4 inhibitor with an IC 50 of 1.9 nM [1]. Roblitinib has antitumor activity [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FGF-401. CAS No. 1708971-55-4. Pack Sizes: 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-101568. | |
| ROC-325 | ROC-325 is a potent and orally active autophagy inhibitor with a strong anticancer activity. ROC-325 induces the deacidification of lysosomes, accumulation of autophagosomes, and disrupted autophagic flux. ROC-325 also induces renal cell carcinoma apoptosis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1859141-26-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103706. | |
| Rocatinlimab | Rocatinlimab (AMG 451) (KHK4083) is a fully human, non-fucosylated, immunoglobulin G1 (IgG1) anti-OX40 monoclonal antibody. Rocatinlimab can be used for the research of atopic dermatitis (AD) [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: AMG 451; KHK4083. CAS No. 2431972-52-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99955. | |
| Rochelle salt | Rochelle salt is an organic-inorganic compound commonly used as a catalyst and complexing reagent. It can be used to catalyze or promote certain chemical reactions, and is widely used in batteries, pharmaceuticals and food industries. In addition, this compound is also used as a substrate or intermediate in some biochemical reactions. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: L-Tartaric acid potassium sodium salt tetrahydrate; Potassium sodium tartrate tetrahydrate; Sodium potassium tartrate tetrahydrate. CAS No. 6381-59-5. Pack Sizes: 25 g; 100 g. Product ID: HY-Y1332. | |
| Rociletinib | Rociletinib (CO-1686) is an orally delivered kinase inhibitor that specifically targets the mutant forms of EGFR including T790M, and the K i values for EGFRL858R/T790M and EGFRWT are 21.5 nM and 303.3 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CO-1686; AVL-301; CNX-419. CAS No. 1374640-70-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15729. | |
| Rociletinib hydrobromide | Rociletinib hydrobromide (CO-1686 hydrobromide) is an orally delivered kinase inhibitor that specifically targets the mutant forms of EGFR including T790M, and the K i values for EGFRL858R/T790M and EGFRWT are 21.5 nM and 303.3 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CO-1686 hydrobromide; AVL-301 hydrobromide; CNX-419 hydrobromide. CAS No. 1446700-26-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15729A. | |
| ROCK2-IN-6 hydrochloride | ROCK2-IN-6 hydrochloride (Comp A) is a selective ROCK2 inhibitor, can be used for ROCK mediated diseases, autoimmune diseases and inflammation research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2762238-94-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156592A. | |
| ROCK-IN-1 | ROCK-IN-1 is a potent inhibitor of ROCK , with an IC 50 of 1.2 nM for ROCK2. Uses: Scientific research. Group: Signaling pathways. CAS No. 934387-35-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-U00351. | |
| ROCK-IN-5 | ROCK-IN-5 (compound I-B-37) is a potent inhibitor of ROCK , ERK , GSK , and AGC protein kinases. ROCK-IN-5 has the potential for proliferative, cardiac and neurodegenerative diseases research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 692870-25-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-153011. | |
| Rocuronium Bromide | Rocuronium Bromide (ORG 9426 Bromide) is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia, to facilitate endotracheal intubation and to provide skeletal musclerelaxation during surgery or mechanical ventilation. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ORG 9426 Bromide. CAS No. 119302-91-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-17440. | |
| Rodatristat | Rodatristat (KAR5417) is a potent tryptophan hydroxylase 1 (TPH1) and TPH2 inhibitor with IC 50 s value of 33 nM and 7 nM, respectively, and shows robust reduction of intestinal serotonin (5-HT) levels in mice [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KAR5417. CAS No. 1673568-73-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-120083. | |
| Rodatristat ethyl | Rodatristat ethyl (KAR5585) is a first-in-class oral tryptophan hydroxylase 1 (TPH1) Inhibitor with nanomolar in vitro potency. Rodatristat ethyl reduces the level of 5-HT and significantly reduces pulmonary arterial hypertension (PAH) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KAR5585. CAS No. 1673571-51-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101124. | |
| Rofapitide tetraxetan | Rofapitide tetraxetan (FAP-2286) is a potent and selective FAP-binding peptide with a mean IC 50 value of 2.7 nM for binding to FAP. Rofapitide tetraxetan can be labeled with radionuclides for diagnostic applications. Rofapitide tetraxetan has antitumor activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FAP-2286. CAS No. 2581741-18-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-147057. | |
| Rofecoxib | Rofecoxib is a potent, specific and orally active COX-2 inhibitor, with IC 50 s of 26 and 18 nM for human COX-2 in human osteosarcoma cells and Chinese hamster ovary cells, with a 1000-fold selectivity for COX-2 over human COX-1 (IC 50 > 50 μM in U937 cells and > 15 μM in Chinese hamster ovary cells). Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK 966. CAS No. 162011-90-7. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-17372. | |
| Roflumilast | Roflumilast (APTA-2217) is a selective PDE4 inhibitor with IC 50 s of 0.7, 0.9, 0.7, and 0.2 nM for PDE4A1 , PDEA4 , PDEB1 , and PDEB2 , respectively, without affecting PDE1, PDE2, PDE3 or PDE5 isoenzymes from various cells. Uses: Scientific research. Group: Signaling pathways. Alternative Names: APTA-2217; BYK 20869; B9302-107. CAS No. 162401-32-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15455. | |
| Rogaratinib | Rogaratinib (BAY1163877) is a potent and selective fibroblast growth factor receptor ( FGFR ) inhibitor. Rogaratinib inhibits FGFRs with IC50s of 11.2 nM (FGFR1), <1 nM (FGFR2), 18.5 nM (FGFR3), 127 nM (VEGFR3/FLT4), 201 nM (FGFR4), respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY1163877. CAS No. 1443530-05-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100019. | |
| Roginolisib | Roginolisib (MSC2360844; IOA-244) is a potent, orally active and selective PI3Kδ inhibitor, with an IC 50 of 145 nM. Roginolisib shows highly selective against a panel of 278 additional kinases [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MSC2360844; IOA-244. CAS No. 1305267-37-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135827. | |
| (R)-Olacaftor | (R)-Olacaftor ((R)-VX-440) is a Cystic fibrosis transmembrane conductance regulator ( CFTR ) modulator. (R)-Olacaftor has good potential for the study of cystic fibrosis (CF) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (R)-VX-440. CAS No. 1899111-41-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-112267A. | |
| Rolapitant | Rolapitant (SCH619734) is a potent, selective, long-acting and orally active neurokinin 1 (NK1) receptor antagonist with a K i of 0.66 nM. Rolapitant does not interact with CYP3A4. Rolapitant shows potent anti-emetic activity in a ferret emesis model [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SCH619734. CAS No. 552292-08-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14751. | |
| Rolapitant hydrochloride hydrate | Rolapitant hydrochloride hydrate (SCH619734 hydrochloride hydrate) is a potent, selective, long-acting and orally active neurokinin 1 (NK1) receptor antagonist with a K i of 0.66 nM. Rolapitant hydrochloride hydrate does not interact with CYP3A4. Rolapitant hydrochloride hydrate shows potent anti-emetic activity in a ferret emesis model [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SCH619734 hydrochloride hydrate. CAS No. 914462-92-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16436. | |
| Rolipram | Rolipram is a selective phosphodiesterases PDE4 inhibitor with IC 50 s of 3 nM, 130 nM and 240 nM for PDE4A, PDE4B, and PDE4D, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (R,S)-Rolipram; (±)-Rolipram; ZK 62711. CAS No. 61413-54-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16900. | |
Would you like to list your products on USA Chemical Suppliers?
Our database is helping our users find suppliers everyday.